LOCUS       DBEJNA010000001        94073 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEJNA010000001 DBEJNA010000000
VERSION     DBEJNA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 94073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.01"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..1209)
                     /locus_tag="ACL3JB_000001"
     CDS             complement(<1..1209)
                     /locus_tag="ACL3JB_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684826.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMN"
     gene            complement(1212..1952)
                     /locus_tag="ACL3JB_000002"
     CDS             complement(1212..1952)
                     /locus_tag="ACL3JB_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684827.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            complement(1967..3574)
                     /locus_tag="ACL3JB_000003"
     CDS             complement(1967..3574)
                     /locus_tag="ACL3JB_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0684828.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKSQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            complement(3571..5511)
                     /locus_tag="ACL3JB_000004"
     CDS             complement(3571..5511)
                     /locus_tag="ACL3JB_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HGR0684829.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            complement(5544..8153)
                     /locus_tag="ACL3JB_000005"
     CDS             complement(5544..8153)
                     /locus_tag="ACL3JB_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0684830.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            complement(8332..8469)
                     /locus_tag="ACL3JB_000006"
     CDS             complement(8332..8469)
                     /locus_tag="ACL3JB_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0684831.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(8671..9258)
                     /locus_tag="ACL3JB_000007"
     CDS             complement(8671..9258)
                     /locus_tag="ACL3JB_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0684832.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            complement(9261..9494)
                     /locus_tag="ACL3JB_000008"
                     /pseudo
     CDS             complement(9261..9494)
                     /locus_tag="ACL3JB_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(9507..9887)
                     /locus_tag="ACL3JB_000009"
     CDS             complement(9507..9887)
                     /locus_tag="ACL3JB_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0684833.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(9880..10220)
                     /locus_tag="ACL3JB_000010"
                     /pseudo
     CDS             complement(9880..10220)
                     /locus_tag="ACL3JB_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10234..10482)
                     /locus_tag="ACL3JB_000011"
                     /pseudo
     CDS             complement(10234..10482)
                     /locus_tag="ACL3JB_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(10482..10652)
                     /locus_tag="ACL3JB_000012"
     CDS             complement(10482..10652)
                     /locus_tag="ACL3JB_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684834.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            complement(10839..11207)
                     /gene="rplL"
                     /locus_tag="ACL3JB_000013"
     CDS             complement(10839..11207)
                     /gene="rplL"
                     /locus_tag="ACL3JB_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0684835.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(11283..11783)
                     /gene="rplJ"
                     /locus_tag="ACL3JB_000014"
     CDS             complement(11283..11783)
                     /gene="rplJ"
                     /locus_tag="ACL3JB_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0684836.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(11822..11957)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(12033..13292)
                     /locus_tag="ACL3JB_000015"
     CDS             complement(12033..13292)
                     /locus_tag="ACL3JB_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0684837.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPSGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(13594..15342)
                     /locus_tag="ACL3JB_000016"
     CDS             complement(13594..15342)
                     /locus_tag="ACL3JB_000016"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684838.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGRVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKRAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(15344..17068)
                     /locus_tag="ACL3JB_000017"
     CDS             complement(15344..17068)
                     /locus_tag="ACL3JB_000017"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684839.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(17126..18064)
                     /gene="msrB"
                     /locus_tag="ACL3JB_000018"
     CDS             complement(17126..18064)
                     /gene="msrB"
                     /locus_tag="ACL3JB_000018"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0684840.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(18359..19228)
                     /gene="thrB"
                     /locus_tag="ACL3JB_000019"
     CDS             complement(18359..19228)
                     /gene="thrB"
                     /locus_tag="ACL3JB_000019"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0684841.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(19230..20516)
                     /locus_tag="ACL3JB_000020"
     CDS             complement(19230..20516)
                     /locus_tag="ACL3JB_000020"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0684842.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(20667..21404)
                     /gene="mecA"
                     /locus_tag="ACL3JB_000021"
     CDS             complement(20667..21404)
                     /gene="mecA"
                     /locus_tag="ACL3JB_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0684843.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(21604..22638)
                     /locus_tag="ACL3JB_000022"
     CDS             complement(21604..22638)
                     /locus_tag="ACL3JB_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0684844.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(22667..24100)
                     /locus_tag="ACL3JB_000023"
     CDS             complement(22667..24100)
                     /locus_tag="ACL3JB_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0684845.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(24116..25102)
                     /locus_tag="ACL3JB_000024"
     CDS             complement(24116..25102)
                     /locus_tag="ACL3JB_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0684846.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(25104..26207)
                     /locus_tag="ACL3JB_000025"
     CDS             complement(25104..26207)
                     /locus_tag="ACL3JB_000025"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0684847.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(26197..27042)
                     /locus_tag="ACL3JB_000026"
     CDS             complement(26197..27042)
                     /locus_tag="ACL3JB_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0684848.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDILPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(27321..28595)
                     /gene="psr"
                     /locus_tag="ACL3JB_000027"
     CDS             complement(27321..28595)
                     /gene="psr"
                     /locus_tag="ACL3JB_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0684849.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(28592..29440)
                     /gene="pheA"
                     /locus_tag="ACL3JB_000028"
     CDS             complement(28592..29440)
                     /gene="pheA"
                     /locus_tag="ACL3JB_000028"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0684850.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(29437..29913)
                     /locus_tag="ACL3JB_000029"
     CDS             complement(29437..29913)
                     /locus_tag="ACL3JB_000029"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0684851.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(29906..31189)
                     /gene="aroA"
                     /locus_tag="ACL3JB_000030"
     CDS             complement(29906..31189)
                     /gene="aroA"
                     /locus_tag="ACL3JB_000030"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0684852.1"
                     /translation="MKLKTNISHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVVTIQGVGMDGLKAPQNALDMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTIPLKKMGVSISGQTERDLPPLHLKGTKKLAPIQY
                     ELPIASAQVKSALMFAALQAQGESVIIEKECTRNHTEDMLQQFGAHLSVDGKKITVRG
                     LQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(31281..31619)
                     /locus_tag="ACL3JB_000031"
     CDS             complement(31281..31619)
                     /locus_tag="ACL3JB_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0684853.1"
                     /translation="MSNIYDSANELSRGLRELPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(31630..32733)
                     /locus_tag="ACL3JB_000032"
     CDS             complement(31630..32733)
                     /locus_tag="ACL3JB_000032"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0684854.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQAMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVVK"
     gene            complement(32743..33909)
                     /gene="aroC"
                     /locus_tag="ACL3JB_000033"
     CDS             complement(32743..33909)
                     /gene="aroC"
                     /locus_tag="ACL3JB_000033"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0684855.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(33919..34986)
                     /gene="aroB"
                     /locus_tag="ACL3JB_000034"
     CDS             complement(33919..34986)
                     /gene="aroB"
                     /locus_tag="ACL3JB_000034"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0684856.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(35005..35859)
                     /locus_tag="ACL3JB_000035"
     CDS             complement(35005..35859)
                     /locus_tag="ACL3JB_000035"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0684857.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(35849..36526)
                     /gene="aroD"
                     /locus_tag="ACL3JB_000036"
     CDS             complement(35849..36526)
                     /gene="aroD"
                     /locus_tag="ACL3JB_000036"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0684858.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(36523..37686)
                     /locus_tag="ACL3JB_000037"
     CDS             complement(36523..37686)
                     /locus_tag="ACL3JB_000037"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0684859.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(38370..40004)
                     /locus_tag="ACL3JB_000038"
     CDS             complement(38370..40004)
                     /locus_tag="ACL3JB_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684860.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(39985..40734)
                     /locus_tag="ACL3JB_000039"
     CDS             complement(39985..40734)
                     /locus_tag="ACL3JB_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684861.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETFSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            40913..42367
                     /locus_tag="ACL3JB_000040"
     CDS             40913..42367
                     /locus_tag="ACL3JB_000040"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0684862.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEGLVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(42456..45074)
                     /gene="alaS"
                     /locus_tag="ACL3JB_000041"
     CDS             complement(42456..45074)
                     /gene="alaS"
                     /locus_tag="ACL3JB_000041"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0684863.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDCEGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(45096..45581)
                     /locus_tag="ACL3JB_000042"
     CDS             complement(45096..45581)
                     /locus_tag="ACL3JB_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0684864.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(45856..46095)
                     /locus_tag="ACL3JB_000043"
     CDS             complement(45856..46095)
                     /locus_tag="ACL3JB_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684865.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(46348..47418)
                     /locus_tag="ACL3JB_000044"
     CDS             complement(46348..47418)
                     /locus_tag="ACL3JB_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0684866.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(47415..48188)
                     /locus_tag="ACL3JB_000045"
     CDS             complement(47415..48188)
                     /locus_tag="ACL3JB_000045"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0684867.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(48185..48991)
                     /locus_tag="ACL3JB_000046"
     CDS             complement(48185..48991)
                     /locus_tag="ACL3JB_000046"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0684868.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDEMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(48972..50129)
                     /locus_tag="ACL3JB_000047"
     CDS             complement(48972..50129)
                     /locus_tag="ACL3JB_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684869.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(50289..51194)
                     /gene="murB"
                     /locus_tag="ACL3JB_000048"
     CDS             complement(50289..51194)
                     /gene="murB"
                     /locus_tag="ACL3JB_000048"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0684870.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(51306..52058)
                     /locus_tag="ACL3JB_000049"
     CDS             complement(51306..52058)
                     /locus_tag="ACL3JB_000049"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0684871.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDASIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(52068..52799)
                     /gene="budA"
                     /locus_tag="ACL3JB_000050"
     CDS             complement(52068..52799)
                     /gene="budA"
                     /locus_tag="ACL3JB_000050"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0684872.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            52941..54212
                     /locus_tag="ACL3JB_000051"
     CDS             52941..54212
                     /locus_tag="ACL3JB_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0684873.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCLLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(54232..55047)
                     /locus_tag="ACL3JB_000052"
     CDS             complement(54232..55047)
                     /locus_tag="ACL3JB_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0684874.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQTGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(55204..55857)
                     /gene="phoU"
                     /locus_tag="ACL3JB_000053"
     CDS             complement(55204..55857)
                     /gene="phoU"
                     /locus_tag="ACL3JB_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0684875.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(55869..56627)
                     /gene="pstB"
                     /locus_tag="ACL3JB_000054"
     CDS             complement(55869..56627)
                     /gene="pstB"
                     /locus_tag="ACL3JB_000054"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0684876.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(56640..57443)
                     /gene="pstB"
                     /locus_tag="ACL3JB_000055"
     CDS             complement(56640..57443)
                     /gene="pstB"
                     /locus_tag="ACL3JB_000055"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0684877.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(57454..58338)
                     /gene="pstA"
                     /locus_tag="ACL3JB_000056"
     CDS             complement(57454..58338)
                     /gene="pstA"
                     /locus_tag="ACL3JB_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0684878.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(58328..59245)
                     /gene="pstC"
                     /locus_tag="ACL3JB_000057"
     CDS             complement(58328..59245)
                     /gene="pstC"
                     /locus_tag="ACL3JB_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0684879.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(59245..60123)
                     /gene="pstS"
                     /locus_tag="ACL3JB_000058"
     CDS             complement(59245..60123)
                     /gene="pstS"
                     /locus_tag="ACL3JB_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0684880.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(60697..62001)
                     /locus_tag="ACL3JB_000059"
     CDS             complement(60697..62001)
                     /locus_tag="ACL3JB_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0684881.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(62002..62775)
                     /locus_tag="ACL3JB_000060"
     CDS             complement(62002..62775)
                     /locus_tag="ACL3JB_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0684882.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(62765..63043)
                     /locus_tag="ACL3JB_000061"
     CDS             complement(62765..63043)
                     /locus_tag="ACL3JB_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0684883.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(63043..63444)
                     /locus_tag="ACL3JB_000062"
     CDS             complement(63043..63444)
                     /locus_tag="ACL3JB_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0684884.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(63654..64271)
                     /locus_tag="ACL3JB_000063"
     CDS             complement(63654..64271)
                     /locus_tag="ACL3JB_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0684885.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(64261..65034)
                     /locus_tag="ACL3JB_000064"
     CDS             complement(64261..65034)
                     /locus_tag="ACL3JB_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0684886.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(65045..65782)
                     /locus_tag="ACL3JB_000065"
     CDS             complement(65045..65782)
                     /locus_tag="ACL3JB_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0684887.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(65787..66917)
                     /gene="hemW"
                     /locus_tag="ACL3JB_000066"
     CDS             complement(65787..66917)
                     /gene="hemW"
                     /locus_tag="ACL3JB_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0684888.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(67001..67390)
                     /locus_tag="ACL3JB_000067"
     CDS             complement(67001..67390)
                     /locus_tag="ACL3JB_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0684889.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(67363..67789)
                     /locus_tag="ACL3JB_000068"
                     /pseudo
     CDS             complement(67363..67789)
                     /locus_tag="ACL3JB_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(67790..68578)
                     /gene="lgt"
                     /locus_tag="ACL3JB_000069"
     CDS             complement(67790..68578)
                     /gene="lgt"
                     /locus_tag="ACL3JB_000069"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0684890.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGFRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(68571..69506)
                     /gene="hprK"
                     /locus_tag="ACL3JB_000070"
     CDS             complement(68571..69506)
                     /gene="hprK"
                     /locus_tag="ACL3JB_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0684891.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(69636..69812)
                     /gene="rpsU"
                     /locus_tag="ACL3JB_000071"
     CDS             complement(69636..69812)
                     /gene="rpsU"
                     /locus_tag="ACL3JB_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0684892.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(69892..70401)
                     /locus_tag="ACL3JB_000072"
     CDS             complement(69892..70401)
                     /locus_tag="ACL3JB_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684893.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSEADMEEMV
                     NYIINHYEE"
     gene            complement(70479..71186)
                     /locus_tag="ACL3JB_000073"
     CDS             complement(70479..71186)
                     /locus_tag="ACL3JB_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0684894.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHVVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            71337..72365
                     /gene="queA"
                     /locus_tag="ACL3JB_000074"
     CDS             71337..72365
                     /gene="queA"
                     /locus_tag="ACL3JB_000074"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0684895.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(73026..73415)
                     /locus_tag="ACL3JB_000075"
     CDS             complement(73026..73415)
                     /locus_tag="ACL3JB_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0684896.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(73469..74176)
                     /locus_tag="ACL3JB_000076"
     CDS             complement(73469..74176)
                     /locus_tag="ACL3JB_000076"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0684897.1"
                     /translation="MFRRNLNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRFEKDETKDRSENHVTIDGEDGYVTTTRTYDVNPETGHVTE
                     KVTVDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(74875..75426)
                     /locus_tag="ACL3JB_000077"
     CDS             complement(74875..75426)
                     /locus_tag="ACL3JB_000077"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0684898.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKVYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(75724..76548)
                     /gene="nadE"
                     /locus_tag="ACL3JB_000078"
     CDS             complement(75724..76548)
                     /gene="nadE"
                     /locus_tag="ACL3JB_000078"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0684899.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKNFV
                     LGISGGQDSTLAGRLAQLAIEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(76545..78005)
                     /locus_tag="ACL3JB_000079"
     CDS             complement(76545..78005)
                     /locus_tag="ACL3JB_000079"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0684900.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLCNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(78121..78609)
                     /locus_tag="ACL3JB_000080"
     CDS             complement(78121..78609)
                     /locus_tag="ACL3JB_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0684901.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(78599..78808)
                     /locus_tag="ACL3JB_000081"
     CDS             complement(78599..78808)
                     /locus_tag="ACL3JB_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0684902.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(79194..79922)
                     /locus_tag="ACL3JB_000082"
     CDS             complement(79194..79922)
                     /locus_tag="ACL3JB_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0684903.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTIMMNTSNDLFIKAIELLPFYSLPLFVVSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(79938..80808)
                     /locus_tag="ACL3JB_000083"
                     /pseudo
     CDS             complement(79938..80808)
                     /locus_tag="ACL3JB_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(81164..81892)
                     /locus_tag="ACL3JB_000084"
                     /pseudo
     CDS             complement(81164..81892)
                     /locus_tag="ACL3JB_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(82138..82449)
                     /locus_tag="ACL3JB_000085"
     CDS             complement(82138..82449)
                     /locus_tag="ACL3JB_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR0684904.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(82464..83750)
                     /locus_tag="ACL3JB_000086"
     CDS             complement(82464..83750)
                     /locus_tag="ACL3JB_000086"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR0684905.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESFEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            84347..84916
                     /locus_tag="ACL3JB_000087"
                     /pseudo
     CDS             84347..84916
                     /locus_tag="ACL3JB_000087"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            84924..86114
                     /locus_tag="ACL3JB_000088"
     CDS             84924..86114
                     /locus_tag="ACL3JB_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0684906.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(86629..87621)
                     /locus_tag="ACL3JB_000089"
     CDS             complement(86629..87621)
                     /locus_tag="ACL3JB_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0684907.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            87781..89535
                     /locus_tag="ACL3JB_000090"
     CDS             87781..89535
                     /locus_tag="ACL3JB_000090"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684908.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            89519..91240
                     /locus_tag="ACL3JB_000091"
     CDS             89519..91240
                     /locus_tag="ACL3JB_000091"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684909.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            91251..91880
                     /locus_tag="ACL3JB_000092"
     CDS             91251..91880
                     /locus_tag="ACL3JB_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0684910.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            91781..92338
                     /locus_tag="ACL3JB_000093"
     CDS             91781..92338
                     /locus_tag="ACL3JB_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0684911.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            92326..93690
                     /locus_tag="ACL3JB_000094"
     CDS             92326..93690
                     /locus_tag="ACL3JB_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0684912.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKKLSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        29184 a        19829 c        16627 g        28433 t
ORIGIN      
        1 attcatatca tctattaaaa tatcctctaa agagtagtat attaaagcca taattttaat
       61 gttaagtaaa aatgcaatta atgaagtaac aaatgtcaaa aatatagcct caccaacttt
      121 aatcttaacc atctggtaat tagaagttcc taaaatttca aattgctgaa tctcaatcct
      181 ttcttgatgc gatgacaaaa atgcaattga aataatattt gcaagtacta tcaaaattgg
      241 tgctcctaca tagacaataa atgccacttt tagctctaaa tcactgtcat cttgaaattg
      301 agatagtata ttctgagaaa tcatttgaaa actagaaatt agtaatatag ctcctgtaat
      361 tgcagcactg atagatttta tataaggctt acgatatagt aaattccact tcgaaacaat
      421 gaacataaaa ttatttctaa atataattat agaaagtagt ttgataaaac atgactgtat
      481 aaaaggagat aattgataaa taatcacaat atctaagatt acaatattga atattatctg
      541 ggccttcgct aaaattgtgc tatcttggaa aatttgttgc aaagaaagca accagataac
      601 actaaaacca gccaatagca gtattctttt tactattgaa agaacatgcc ttattttaga
      661 actcttccta tttctaatct tcttgaacgt ataaaagcaa ccacttagaa aggctaaaaa
      721 tgaaatcaac actactgtaa tgatacatcc aacagcactc gtttgaaatt ggatatcagg
      781 taatatattt tccccgaaaa agtattgtaa aaaataataa taatttgacg taacaaatat
      841 agagcataga tatgcaataa aactaataat cgaggaaatg ataaaaatct gtccccccac
      901 aagaaatgat agttgaagga gacttgctcc caacacctcc agaagttcgt aatcatctct
      961 aaaaatttca accaacatat ttattatgtt agagagcaca aagaataatg ttactcctcc
     1021 gaatactatc ggaaacataa aaattggttt aggatctgga agtccgacaa atacttgcga
     1081 attattctca acattaatta ccccattaac agccaatccc ataactaaac tcgaaacaaa
     1141 aattactggt gaaacgccta accattgttt cttattatgt aaaaattgat agtaaactaa
     1201 tctgagcatc tctattcctc cgtagttgat tgtacctcta agattttata caactcttcc
     1261 ccgctaggtc tatgaagttc tttgaaaatt tttccatctt tcaatattaa tgcacgatca
     1321 gttttcgagg ccaattctat atcgtgcgtt accataatta cacacttacc cgcccctact
     1381 aactctctca ataattcaaa aattacttca cgagaaacgc tgtctaaagc cccagttggc
     1441 tcatcagcaa atattatatc actatcagca ataaccgctc tagctatagc aaccttctgt
     1501 tgttctccac cagacagagt tccaacaaaa tcgtttaagc cagcattaaa cttcattctt
     1561 ttgagtaagt tttctacatt tttaatagtt aatttttttt gtgataatcg caaaggaagt
     1621 gctatatttt ctattaccgg cagggaaggt attaaattgt atgcttgaaa tataaaagat
     1681 acttcgttac gtcttatact tgacaatttt gcatttctga ttttataggg gttgattcca
     1741 tttaaaatta cttccccact tgttggttca agcaaactag aaatacattt taataaagtt
     1801 gactttccag aaccactaat tcctagaata cttataaatt ctcctctcga agcagaaaga
     1861 gaaacatttt tcagcacttg caacgtttta ttatttccta gtaaaaattg atgatacagc
     1921 cctttcactt ttaatatata atctttatcc atattcttgc ctccaatcac ttaattttga
     1981 aaagtgttcc attttccaat ttatatatat cagtgtatct cttgtcattt aagtcataat
     2041 gatgtgaaac ttcaataaat gaaataccta aattgaacag aatatcatgt atggaatttg
     2101 aattatcatt atctaaatta gctgatattt cgtcaaataa gtacacttta ttatttctaa
     2161 tcagagctct agctaaagct attttttgtt tttgacctcc agacaaatta ctaccatttt
     2221 caccacattg ataatttagt atatctatct tttctaattc ttcatataga tttacctttt
     2281 ttaacacctc aattatctga tcatctgaaa aatattcatt ttgaaataaa gttacgttct
     2341 cacgaatagt agtgtcaaaa atatatggtg tctgatcaac tgttggtatt gaatctgaac
     2401 tctttttccc atgtgataac aaatttacat aacctttttg tgactttaaa gaaccattaa
     2461 ttaaatttaa aatcgttgtt ttcccactac cagaagttcc tgttaataat accctaaatg
     2521 gtgacttaaa tgagaagtca atacttaatt tattttctgg tgtaatagaa tatacaacat
     2581 ctttcatgtg tatctcatct attgatgaag tatacagtcc gttattatca tgttcagcgt
     2641 ctataaaatt cttctctcca cttaagtatt ttaaaaacgg tttccttaaa tctttggttg
     2701 tatttatctt atttaatgaa taggcaattg attgtatcgg ccctaaaact ttatcgtttg
     2761 ctaagaaaat acctatcagt tcactaaaag aaaggctttt atgataaatt acaaaataac
     2821 atcctacaac caagggaact agaaagcaaa aacctgaaat tagtactgca accaattttg
     2881 aaagaacctc tgatcgtttc aaattaaaag tagaatcttc tagtttatcc aactttttat
     2941 ccgacaaact aattatttct ttagtaacag aataagattt taatgtctta aaaccattaa
     3001 aaatttcttt tattatgtga gtatactctg cattgctgtt agagtactca ttagctgaat
     3061 tagacaacat cttcttcata aagacaggta ctataatcgg caatgctgat aatacaataa
     3121 atattattga aactaggaag tttaaataaa gcataaaact tagagagacg atgaacaaca
     3181 atattgaaga aattatttca aaaatttgtc taaaatagtt ttcttcgatt aatctcaaat
     3241 catttgacaa aactgaaata atagatgagt aatctttaac catttcagaa gaaagatact
     3301 gttctctaaa atatccttgt ttaattttta catttatatc tttcgttatt gatgcttccg
     3361 ttacttctaa atagtaattt gatatataga ttgctgacca acccagaata cttatagcac
     3421 caaatcttag aacgtcagaa aatgaggaag tctgatttaa actacctgca tatacaataa
     3481 ttcctgagag caagacacca ttaaacgaag atagaaatat taaaatcccc attaatataa
     3541 gtttagtctt ttttataaat tttaaataat tcataagtta ttccttccca cttcttcaaa
     3601 gaaataattt aaagtatcaa tcattaagag aacatctgat ggagtaaaac ctccatgacc
     3661 agctgctttg tttaaataca acaaactttt aactccaata gaatttaatt tctttgacca
     3721 ctctatcact tcgttattat taatatatgg gtctttctca cccaaaatat taactataac
     3781 agtatttgag tctcgtgcct tttcaatatt ttgcataggc gaatatgact ttatataagc
     3841 ctttacttca gggtctctaa tatctcccca ctctgctatt tcggtcttag aaagaggatc
     3901 atttggattc tgaagtgtat cataaggatt tataaatggc gaaaataaga gaatgctttg
     3961 caataaattt ttttcctcgt tcaacaccgc accagcaatt attccacctg cactagaagt
     4021 tattaaacct aatcgcttac tgtcaattac atcattttcc cttaaataat ttactccctc
     4081 aataaaatct ctgatagaat tccatttgtt taacgccttt cctgagcgat accattcacc
     4141 acccaaatag cctccacctc ttacatgaac tatagcataa ataaaacctg catctattat
     4201 agataacata atttcatcta aatcagaatt atcattctta ccataagccc catagacact
     4261 tagaatacat ttttttcttc ttgggagctc atccgtatct tcacttttcc aaaataaaga
     4321 aatcggtatg cttacatcat aactgtcttt tttagtccaa atcaccttag aaaaatattt
     4381 agtattattc gattttatga tgggtctttc aaattcagtt tttaatgtat tttctattaa
     4441 atcaaaacta agtatttttt cgtaaaaagt tctcctctct aaaaacagaa gaacacgatc
     4501 agaaaatgaa ttttcataaa gtgttgtctt ttcatcaaat gttatcttat taacactcaa
     4561 ctccctcaaa ctattatttt taaatgtagc aagataaaag acggaattcg ctgcgtttga
     4621 acagtctaaa aggatataac gtcctataca gtgaactctt ctagccctat cttgatatgg
     4681 tatagtaata gaaactctgt ctcccgaaga agtttccctt agaattagtt gatctttctt
     4741 ttcttcagtt gaagagagcc caagaaagta ctgtgctttt tctgtactaa atagagcgat
     4801 atctctaggt gttggggcta ccgtttctgt gtaagagtgt ctaacaaaac ccgtccggtc
     4861 gaaactgtat agaaaaatcc tgcctttctg aaagtctact gactttacaa aacaattatt
     4921 gctatcaatg tggactattt ttaatcgaaa agagcattcg ttttcttcaa acagttcctc
     4981 ttctgtaaag ctatcaaaag atttatagaa taacttactt ggcctcccgt actctttgga
     5041 gcgagtatac ataacaccga atttacccaa atagaacgaa ctttctactg aaatatcttc
     5101 aatgataaat aactcttcca tagtatattt ttttattcca attaaattag tgctacgcag
     5161 tgaggataca accaaaacta tataactctc atcagatgaa atcctaacat cctgtaagat
     5221 actatcatct ggcaaagtat atttttccac atcaaagaca attttaagtg aatttgaatt
     5281 gtctaaactg gaagaactaa ccttaggaat ccagtcatta tcttcgacat accattcctt
     5341 tattacacca gtattgggta tactccaatt atcaaattgg taccaatatc gccctctcct
     5401 aaatatcaaa gaattccatt tttttaattc ctgaaatgat gaagagatag acctcttata
     5461 gtgtgttttt tcctgtattg tatttaaaaa tatttcatta ctctgattca caagtatgac
     5521 cccttaataa tggtatctaa atattatatt tgaggaagaa tcgtcaattt attatccatt
     5581 attgatacca atccaattgc aacacccgca aatcccgaag caatatctgt tgttatcttt
     5641 aaaccattat ctcccgcaat aacaaatcct tcttcaatta cacacaaata tctataaagt
     5701 tgttcaatta atttcttttg tcctgaaaag ttatcatcga tatcactata tatattatta
     5761 gcaacttcaa gaccacaaaa tccgttaaat aaacctggta atacacaaaa aactacatca
     5821 gttgccctct ctaaagaagt taaatatttt aagtatttgc ttgacaagat ttctttattt
     5881 ctattaataa gtaaaagcag gccagcactt ccagttgcta gatatggtag taatctatga
     5941 ccttggctgt actgcaatga attattacta tctactttat aagcaactaa ttctttatct
     6001 acagccaatt ctagaccatt tttatagata ctttcaccag ttaatttata agcttcaccg
     6061 aagagccaag ctacccctgc gtgaccatat agtaatccac caaaattctc ataaggatca
     6121 ttactctgaa catcactagc gccaacttta caaaaagttt ctggattttc tatataattt
     6181 aaagtatatt ctctaagcct aattagtatt tcttctccta gtttattatc aatttcccct
     6241 ttactaagaa aatacagtcc aaccagtaaa attccagcct gcccactata taaattttta
     6301 ttttgtgaat tctcaaatat ctctataaaa tgagttgtaa aaagttcaac tgcccgatct
     6361 atctccccaa attcataaat gagccagatt gtaccaattt taccatcaaa aagaccagaa
     6421 agggacgatt tcttaaaatt atttactgcc tcattaataa cctgtgttcg aatctcataa
     6481 tagtcatcaa acttgaaatt ttttactttc ttagctagtt gttgataact ccaaaggata
     6541 gctaaatctg aaaacgcaat tccttgatta aaattcagac cataataatg aactgggaag
     6601 aatcttgatt gaaattcttt acgccactgt ccataagtta gcgtaaaccc tctcaataat
     6661 tttataataa aatcttgtat atcttgctca ctctcgatag ttctaatctc atgcatgggt
     6721 tttaaaactt ttttcctgga aatattctca atctgtggac atttagaatc tagatatgac
     6781 aataaacttt ctacataatc tatatgttct cttgtataac ccaaagactc aaatagtttt
     6841 tttccttcta tcctggtttg acttacatag ttgtatgtca aatccgatgt agttactagt
     6901 ggcatgtata aataatgagc tatttgtcta ataccatacc aatctatctc actgggaagt
     6961 gtttctcgcc atgctctaaa accaggggct gcaactttat gtacaacttt ttcatcattt
     7021 gaaaagacag cctgttccca gtctattata ctaatctcat cttcatcctt aaccaagata
     7081 tttcctaaat gtaaatcttg atgatataca ttttcagaat gaaacttatt cgttaaatcg
     7141 atgagttttt ctactatctt tgaaactctc aatagataat ctttggtctt atcaacaact
     7201 tcatataaag gaaaattatt ggtaacccat ctatttagtg gaacgccctt catatgttca
     7261 attcctaaga aggtgtgctc ccagatctta ccgtgccagt atattttagg cgtctcactc
     7321 cattcattta gaatttttag tgctttgcac tccgaagcta atttctctga agaataagta
     7381 ccatcaaatc ctagacctgt atacggtcta gcctctttta aaattatttt tttcccatct
     7441 tcttttagcc tagcattata tatcccacca ctgtttgaaa atctaattgc attatctata
     7501 ataaagggaa agtctccctg ttttttatct ttcttgtcaa gccatttatt caaaaagtca
     7561 gggggcacta taccttttgg aattttaaat actggtaaac gttcatcttt aacaacttca
     7621 tcgccaacaa ttaattcatc aatagcaacc ttcttttcat catcccttga cggcctaaac
     7681 acaccatacc tcagatatat tggtgcttca tcccaacgtt tatcgcttaa aatatatggc
     7741 ccattatatt gctttaaggc actttctaac ctttgcaaaa ccgactctaa ttcattttga
     7801 tttggataac atgtaataaa tttaccagaa aatcctcgac taaccaattt cccgtttcgc
     7861 atgataaatt tgtcttctgt actaagatgt ttaaatggaa ttcgcatttc atggcaaatt
     7921 tttgctacat cttgtaacaa ttcatgtgaa ctgttatact ctgaactaat gtgtattttc
     7981 cacccttgtc tttcaacaaa ttttccaata gggtattgat aaacccactc atcattattc
     8041 attacttcgt gccaattaaa aggcagactt acttggtact ttatgctagt atctgtacta
     8101 taatcattat tagtgaaaaa gaaaggatgc tccaaattga aattataatc cataacaaaa
     8161 tctccaagaa attttatcaa acttaatata tctatagcta gacagactta tttaaataaa
     8221 aagggagaat cctttggatt ctccccatat aagcactaac attccaacgt gcacatattg
     8281 gaacgacatc cataactcca gagaatctct aaagtttaca atttaaatga attaacaatt
     8341 ttcccaacta aaagcactcc agttaccgca acgatttgta ctgaatgtac taaatcgcat
     8401 tccatcaact tcatctgttt cgtcaacttg aacagatact aattgaagat ttaatacttc
     8461 ttctgccata gctagctcct actatttaaa tttttgggat taagtacttt atccaccctc
     8521 attatactct ctccaccagt aaaatgcaag caattataca atgttgtcac atagaaaata
     8581 atgtttccgt aacttttcaa agtaacttcc atctctctcc caaaactgga agttagtttt
     8641 agaagttacc taaaaatcag gtcacctatt ttaaaaaagc agcaaactat aaactagtag
     8701 gttccacacc aaatgtagtc ccatactgcc ccataagtca gatttatagc gcaccatacc
     8761 taaaaacatc ccaagtgaaa catacaaaca ccaagctaga atggttcctg tatgatgtgc
     8821 taaggcaaat aaaacacttg tcaaagcaac tctgatatct aattttctga ccaaattcca
     8881 taaaatttct cgatacagaa attcttcaac catactcgca ttgattaaga acaataaaaa
     8941 tgaaaaccaa ggaatttgat gttgaaggcc aattaagttt gcttgattcg tgcttccttg
     9001 agcatgaatc agactaaaac atagacttat aatcagtagg ctaacaaatt caacaccaag
     9061 ccatttcatc ctagatttca tattgacctt atgcgcttgt ttgcgttggc catacatcca
     9121 taaaaaagaa atgagtgacg aaccatagag aatctgtagt atagttaact caccgataca
     9181 aagaaatttc aataagtata gagataccaa taggacattt acttgttgga atatataaac
     9241 tggaattatt cttttcatag ttacctccga aataaatctt cataatctaa atctaatacc
     9301 tgcacaatcc tttctaccca tggactttga ggcattcatt gttccatctt ctagtggcga
     9361 atcttttgat acaaacgatt caattcactt ggatagtgaa actctcccgc aaacattttt
     9421 ctggttaact caatccagct gatatttctt tcagccaaaa taatggacaa gttctcccaa
     9481 aatcgttcag ccatattgct tctcctttag ttagataaat aatgtgtttg cgccatgtaa
     9541 atcaattgtt tcgtatctct tggcaataga gctctagcct cttccaaatt cagacttgga
     9601 taaactcgct tatttgaaac cgcaagagga agtctgatgg ttagttcagg attttttaaa
     9661 attatctcaa cgaaatccgt taatcttaga ttgtcacggt tcttaaatcg taataaattg
     9721 ggagataaaa actcaaaaca atctgaagaa tagctcatca tctcaattaa tttgtccttt
     9781 gtcatttcag aaactgaatg acaagatacc tctatgccat agttttggaa gaaatctaaa
     9841 agaagttgat ttctttgtct atttttactt agatagagat caatcatggg agacctccca
     9901 aagattcggt tccatttgat attctgacac gattaaggaa tctaataaat taaggaatct
     9961 aataaatttg cgaagttaat cggtttcttg tcttcatcat aagcttttac agttacttgg
    10021 gttgtaagta ttccctcttt tccctcggct cgatagcctt gtccatataa aacaaaaacg
    10081 agattttgat gatcatctac aaaggcatca accccattct ttatgtcttg actttcaagg
    10141 aattccataa cgttttgaag ataggattcg taaaatagtg ggtagttatg ttttttatgg
    10201 taatcatcta aaaatgtcac ttcaaactca catggagagt aattttgact ttgaacagcc
    10261 taaaagtgcc atcaaatttg aattggaata aatcaaataa atagccccat cctcatcaat
    10321 ccaacctttg ctcaaagaca actccaaccg atcttttaaa actgagtaaa ccaccttaac
    10381 ctccagtttc atattcttat accgttcact ctcaaataaa agtttgggga gcttataata
    10441 acgctctgat gtctgatatt gattagcggt aatacgcttc attattgtcc ctccaagact
    10501 aaaattccaa catttccaaa ttcatcaaat cggattaaac ctacttgttc catttcatca
    10561 actaactgag ttgcttttac aatatcaact cccatgatag tcatgagatg actcttcacg
    10621 aattgacgtg atgactgtcc ttccttttgc ataattacct ccgaaacaca aaaaaagggg
    10681 tagacaatct agtgtctacc cccgaaagtt tattaaaaca aaaatcctgc caaagaattt
    10741 ttggcaggaa accaaatcaa tttatcagtt tctatcaatc gcttatcgct ctcaaagact
    10801 ggtaaatagg gattccgcaa tcaaattgcg atactctatt atttaagagt aactgaagct
    10861 ccagcttctt ccaatttagc tttgatttct tcagcttctg cagttgcaac gccttcttta
    10921 acaagtgctg gtgcaccgtc aacaagttct ttagcttctt taagaccaag accagtgatt
    10981 tcacgtacaa ctttgataac gccaactttt ttgtcgcctg cagatgtcaa ttcaacgtcg
    11041 aatgaatctt tagcagcacc agcatcagct gcatcagctg cagcaacagc tacaggagca
    11101 gctgcagtta caccaaattc ttcttcgata gcttttacaa ggtcgttcaa ttcaaggatt
    11161 gaagcttctt taatttcagc aataatgttt tcaatgttca atgccattgt tatttcctcc
    11221 aaataagttt taaattttat aatagttttt ttcgtagcta ggctacgctg tgtagcttaa
    11281 gattaagccg cgtcttcttt gctttctgca accgctttga ctgcaagagc aacgttgcgc
    11341 actggcgctt gaagtacaga aaggagcata gaaagaagtc cttcgcggtt tggaagagtt
    11401 gcaagtgcaa gaatctcttc tttagatgcg acagcgcctt cgattgcacc acctttaatt
    11461 tcaagtgctt cagcgttttt agaaaagtcg ttcaagattt tcgctggtgc gataacatct
    11521 tcattagaaa atgctactgc agatggtcca acaaatacag atgcaagatc ttcaagacca
    11581 gctttttcag ctgcacgacg caagattgag tttttaataa ctttatactc aacttcgctt
    11641 ccacgaagct cacgacgaag aactgtatct tgctcaactg tcaaaccacg agcgtctaca
    11701 acgacgatag atgcagcagc tttcattttt tcagctacta cgtcaactag ttccgctttt
    11761 ttagcaataa ttgcttcact cattagtgtg ttcacctccg taattatttt gcttggggaa
    11821 tttttcaaaa agaaaaacgc gcccaaacct agacacgaaa gtacaatacg cttcttttta
    11881 catgatacgt tttgtcctcg gtaggatatt tatgagtcga gctcccctac tgtcttaggc
    11941 agttttttta aaccgtatat aagtatagca tagtcaaaaa aagaatgcaa gatttttgca
    12001 aacttttttt aaaatttttc gtaatttttc ttttaaagtt ctactgtcag gacttgacct
    12061 tgcttaacaa cctgttctcc ggcgatataa acatcatcta catcactaga tttaactgca
    12121 taaaccaggt gagacagcat attttcctga ggttggagat gaattttccc ttgtggttga
    12181 atgaccagaa aatctgcttg cttgccgact tccagacttc ctatctgatt ttccattcca
    12241 aggaccttag ccccttcgat tgtcagtacc ttgagagctg tttcgattgg aaactggctg
    12301 gcatccccac ttttcatctt ctgaagaaga gctgcagtcc ttccttcctc aaacatatct
    12361 agattgttat tggaagcaac cgagtcagtc gcaattccga ctgctactcc cgctttttgg
    12421 agctggataa ttggagcaat tcctgatgcc agtttgaggt tactgatagg attgtgggcg
    12481 atagccactt gagaagatgc caagcgttca atttctctct cgtttaattc gaccccgtga
    12541 gcaaatacgg acggatgatc taaataaccc agttcttcaa gaaaagcaag ggggcgtttg
    12601 ccgtatcgtt tgaggataat tcctgactcc tccttggtct ccgccacatg gacatggagc
    12661 ggaatattta gctcttttgc catttccaaa ctcgcttcca gcaagtctct actgcagcta
    12721 tacggagaat gaggtgctac cataaccttg aaatttggat ttttatattt taagatttca
    12781 tctatgatgg atcgagttct gcttatagtc tcagcagttg tttctgtctc tgaagaaaag
    12841 agagtcggag aaaaataaca acgcatcttg gaagttttca ccacctgata aatttgctgg
    12901 atatccacac cactgggatt atacatatcg ttaaaggttg ttgttcctga ctggagcatc
    12961 tctgtcaagg cttctttgac cgcattggta gtcatgtcgg gagtaaactc agattctgct
    13021 ggccagatat agtcattgag ccattcatgg agattgctgt catctcggat ccctctcaga
    13081 cctgtcattg cagaatgggt gtgacaattg accaaaccag gcataatcca agctccctga
    13141 tagtctataa tctgctcagc ttgttctaaa aacgctggct tatcttgacc gacatagacg
    13201 atttgagaat ccttgactgc taagattcca tcaagataaa catggaaatt ttgatcacaa
    13261 gtcacgatat ttacatgctg aaagactttc attgtaggct ccttttctaa aagacaagtt
    13321 gtactctctt caaaccactt cagattcact ttgccgtagg tgtggttact gacttcgtca
    13381 gttctatctg caacctcaaa acagtgtttt gagctgactt cgtcagtctt atctacaacc
    13441 tcaaagctgt gctttgagca acctacggct agcttcctag tttgctcttt gattttcatt
    13501 gagtattaca gtgaacaatt tttctagcta ttgtaacaaa aaagtcactc gaaggcaact
    13561 tttttcgtcc ataaactttc aaaagagaat cgcttattca gaactaaaag ccgcagcttt
    13621 ttgcatttgg taatacttac cctttctatc catgagttct tgatggttac catattcaac
    13681 aatatcacca tctactaaga caagaattaa atccgcatcc tgaatggttg acaaacggtg
    13741 agcaatgatg aagcttgtgc ggcccttcat gagttttgca aaggcatcct gtaccagcac
    13801 ttctgtccgt gtatcaatgg aagaagttgc ctcgtctaag ataagaatct ttggaatagc
    13861 cagaaagact cgggctatgg tcaagagctg agcttggccg acagagagag attctccagc
    13921 attttccaac ttggtatcgt atccctgtgg aaactgttgg atgaaaaagt ctgcattagc
    13981 tgctttggca gcagcaatta cttgctctcg actggcttca ggattgccaa aggcaatatt
    14041 atcatgaatg gtcccttgtg tgagccaggt ttcttgaagc accataccaa actgctgtct
    14101 caatgatact cgtgtataat cataaatgga ttgcccatcc agcaagatat ctcccgagct
    14161 aatgggataa aaacgcataa ggagattgat aagagttgat tttccagcac ctgtcggacc
    14221 aacgatggct accttactac cagctggaat atcgatagac aagtccttaa tcaaaatttt
    14281 ttcaggatgg tagccaaaag agacatgttt aaaggaaata gctctcttaa cttggtcact
    14341 ggtcaagact tccttacctg tttcagccac ttcagggcta tctaagactc catagatacg
    14401 ctctacgcaa gccagagcac tttgcaactc agctagcact gaagaaatat cgttaaaggg
    14461 cttggtgtat tgctgaacat agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga
    14521 acccatcatg atacgataag ctcctactcc agctaaaagg gcataaatga gtgcatttac
    14581 aaagcgagtc gaaggattga ccgttgaaga ataaaagatg gctgactgag aatagcctga
    14641 gtagttgtca tgagcctcac gcaatctttg gataaactct gtttgagcat tgaaggactg
    14701 gattatagtc tgctggctaa gcgattcttc aatcaactgg gtctgaatcc ccctcgtctc
    14761 tgtttgcttc tggaagagat gataggatct cttggcaata aagcgtgaaa tcaccatgga
    14821 cagtggcgtc aacagcaaga ctaagagagt catgaggaga tgaatttgga gcatggctag
    14881 aatactaacc aaaatcatca aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc
    14941 agctgccaac tgttcgatgt ctgtggttac acgactaacc atctctccac taccttgcct
    15001 atctacaaag gcaatcggta accgatggag tttatggatg attcgctccc gtaaatctct
    15061 ggtataagag aagattagac gattatagag gagaggattg gcccattgta ctagagtatt
    15121 tcctattacc accaagagca tctggagaaa aatctgccaa aaaactggtg atgaaccagc
    15181 cactaggact tggtcaatga cccgcccaat cagaataggt aggtaaattg ataagccaac
    15241 ttgggcaata gttcctagaa aggctaggaa aaggaggaaa ggatggcttg ctaaatctac
    15301 ggctaaacgt ttgagcgtct ggtttacagt ttgtcgtttc attctagtcc tcctttccat
    15361 gttgggatgc attgatttca caatagactt ggctggattt catcaagtca tcgtgcttgc
    15421 caacagctag caactcacct ttttccaaga ggagaatctg gtccgccatc tgtaaagttg
    15481 aggttcgttg agagatcaaa attaagctcg tgtttggaaa attttctcta atagctttca
    15541 agagcttgga ctctgtaatg gtatccagtg ccgaggttgc atcatctagg atgagaaacg
    15601 gagcttggcg caagactgct cgggcgatag acaatctttg tttttgtcca cctgagaaat
    15661 ttcgcccccc tgcctcaact agagcatcca agagtccttc cttttcactg acaaaatcct
    15721 tagcttgcgc aatctccaag gcctgccaga gttcctggtc agatacttct tgattgaaac
    15781 ctagagtcaa gttggaacga atggttcctt taaagagttc gaccttttga ggtacatagg
    15841 caatccaaga ccgccactgc tccaaattaa gaggactacg tccattttga taaaggtcaa
    15901 tgttcccctt gtctactgga taaagtccaa gtaagagttg caccaagctt gatttaccag
    15961 aaccagtccc cccaatgata ccaaggattt gtccttgagt catatcaaag gaaatgtctc
    16021 tcagagaagg ctgggccgca tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc
    16081 gaccactggt aacttgcttt tgttctaatt ctgaatggat gttttcggga gattccgcaa
    16141 agacctcctc gattctcttg gctgagatat aggactggtt gagggaattg atcagcatgg
    16201 caagcttgac caattccacc aaaatctgta agaggtaatt gataagagca atgagagcac
    16261 cttgactgag cactcctcct tgaattgaaa tatagccttg ccagataata acgagaagag
    16321 ttccattgac aatcagatag gtcagaggtg ttaataaact agaccagaaa cctgtctttt
    16381 cttgtaatct agcataaact tggttaaggg tttgaaaaat ctgtaactct cgtttttctt
    16441 gaccaaaagc acgaataacc cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt
    16501 ggtccgtttt ctttctgaga ctactgtaga gaggattgac caatcgagat aaccctacaa
    16561 tgacaatggt caaaatggca accatgacta agaaccagaa agtcaactca gctgagattc
    16621 gataagccat aaaaatggca ccaaaaacga taatgggcgc tcgcaaaaag agacgcagga
    16681 attgattgat accagtctga atctggtagg tatccgaagt caagcgagtg accaaactag
    16741 aagttgtcag acggtctctg ctgtccttgg acaaggaaag aatatgacga taaagatcgt
    16801 ttgtcaattc cttagcaaag cctactgctg cctttgctga gtaaaattga gctatcaagg
    16861 ccactaaaac gccaattact gcaaagataa ggagcaggcc aatctgcatc cagagatgac
    16921 cttgatctcc ctgaggtaaa gattggtcaa caatcccagc aatcaccatg ggaaccaaga
    16981 gctcaaaaac agcttctaac agcttgaaca agggggctaa aattgattcc ttgatgtagg
    17041 gtttgaagta agataatagg tgtttcataa atcccttcta ttcatattct agaaatgaag
    17101 aaagtgggaa gccccactct ctgttttatt tgtttaagta aggcaataga tagccatatc
    17161 ctgctttttc catctcatcc ttggccacaa agcgtaaaga agcagaattg atacagtaac
    17221 ggaggccgcc taactcccgc ggtccatctg tgaaaacatg acccaagtga gcactgcctg
    17281 aacgagaacg aacttcaatt cgctccattc catggctcag atccttgtaa taatgaatca
    17341 actctttgga aatcggacgg ctaaaacttg gccaaccaca acctgaagca aacttatcct
    17401 tggcaaaaaa gagtggctca cctgtcgtaa tatctacata aatcccctct tcaaaggttt
    17461 ggtcataggc attggtaaat ggagcctctg tagcagcttc ttgtgtgaca cgataagact
    17521 cttcagatag actggccttc aacacctctt gactaggctt ttcatagttt gctgcatcaa
    17581 tcaatggctt atcagcatcg gtcacatcga tatgacagta acctgaagga ttcttcctga
    17641 gataatcttg gtggtagtct tcagccagga tgtagtggcg taattgctcc acttctactg
    17701 caatctttcg acccagcatg cgttcctgct cctgtaccac tgtgtagata gctggcaaat
    17761 ctgcttcatc ctgataataa atcccagttc gatattggcg accacggtca ttcccttgtt
    17821 gattgataga tagaggatcg ataactcgga aataataaag taaaatctct ctgagtgaca
    17881 cttccttctc atcgtaaatc acttggaccg tttctgcatg gtctgtttcc ttgatcaact
    17941 ggtaattggt cgtttcgact tgaccattag cgtagccaac actggtttct agcactccag
    18001 aaatgcgtga aaaatattcc tctaggcccc aaaaacaacc acctgctaga taaatttctg
    18061 ccatctttat ttctccttta tcacgttttt aactaatact cttcgaaaat ctcttcaaac
    18121 cacgtcagcg tcaccttacc gtatatatgt tactgacttc gtcagttcta tccacaacct
    18181 caaaacagtg tcttgagctg acgtcgtcag ttctatccac aacctcaaaa cactgttttg
    18241 agcagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aaacttcttt
    18301 tcacaaaaag gatatgaaac cctctggtca agagtttccc catcctatct tctattcttt
    18361 attttgcttc tacacggaca ccttgggtat caactctcaa gtcatgcagt tttcctttga
    18421 aaggttgctt ttccaattct gccttaattg ttggcatctt gtcatgagaa gccagaacca
    18481 taactgtcgg cccagcacca gaaaggtagg ttgcataggc cccattttct ttggtcactt
    18541 gcttaatcat cgcaaattct cttaccaagt cctgacgata gcgctcatgg aagaggtctc
    18601 cctcgattgc ttgcccagcg gtcaccatgt ctcctgccaa caaggcagca accgctacat
    18661 tggcgataga acttgcagca acagcttcct tataagataa ttttttaggc aagacactac
    18721 ggctgtcgcg agtacgtaat tcatagtttg gaatgtaagc tagaaaatca cactctggaa
    18781 agtctgctac gatagcagag acttgccctt caacagaact tgcaataacg agattaccat
    18841 aaatggctgg agccacattg tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt
    18901 catggtctga taagttgagt tgacccagtt ggttggctag ttcaatccca gcaacgataa
    18961 ccgagctgga agaacccaaa ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc
    19021 ttggttgcaa gtctggtaca atttgcaaag cgattttgag caagagatta cgctcatcat
    19081 gtggaatcca tttgccaatc tggtgttcaa tcagccactc atctcgttct tcgcagacct
    19141 caatttgaag atacttggtt acagctacac cgaccgagtc aaaacctggc ccgatattgg
    19201 cactggttgc aggtacaata atcttcatct tattctccta gcaccttgaa ggtattcaaa
    19261 aggtcgaatt ctgaaacctt cttcaattca gctgagacat tttcaagctg ggctttatta
    19321 atcttgtgtg tgatgataac gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt
    19381 tgcttaaagg aaatatcttg agcattgaag atttcagcca acttcaagac ctgacctttt
    19441 gagtctagag ccaagattga gaaatagtag tttgctttga catcttcagg atttgccaag
    19501 accaagtcac ggctatattc gttgaagtct ttgccaatag taccatcatt caaacgacga
    19561 acgatacgga caatatcagc tacaacactt gttgcagttg gtttttgacc agcacctggt
    19621 ccgtagtaca tagactcacc aataccgata gattctacaa agacagcgtt cattacgcca
    19681 ttcacactag caagtgggtg cgctttaggt aggaaggttg gagtcacttc tgcagcaata
    19741 cctgaagaag tttcctcaat agaaccaacc aatttcacta cgtaaccaag ctcttgagct
    19801 acagctacgt cttctggtgt gatattgcgg attcccttgt gggctacatc atcaaaggca
    19861 atcttcatgc caaaggcaaa ttggctcaaa ataaccatct tgtaggctgc atcaatccca
    19921 tctacgtcat tcgtcggatc gctttctgca aatcctagac gttgtgcttc cgcaagagca
    19981 tcatcgtaag accagccttc ttccaccatc ttggtcacca tgaagttgga agttccgttg
    20041 actactccaa gcacgcgcgt aattttatca gaagccaagg aatttgctaa agtacgaaga
    20101 attggaatcc caccagcaac tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg
    20161 atttctagca attctgcgcc atggacagct aaaaggtcct tgttagcagt aacaacgtgt
    20221 tttccagctt ccaaggcacg agtgataaag gttttagcag gctcaatacg ccccatcaat
    20281 tccactacga tagtaatatc ctggtctgat aaaatatcat ccacattggt tacaaagtta
    20341 aagtcattcc ctgctgcaag caagcgattt ttttcatctt catccttgac caatacctta
    20401 gcaactttga tatctgaatg tgctgattga ttgatttttc ctccattttc ctttaggagg
    20461 aaaggcacac cacttgcaac ggtaccaaat cctagtaaag caattttaac tgtcatcttt
    20521 atctcctcga aattttctaa tatagccatt ataacagaat tttgtgaaaa ttcctattat
    20581 agtaaatcac tatttcagta taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa
    20641 atctgaaaat agctttccag aaaggattag ccgatttttt gcagattgag cactgcatcg
    20701 tgactcatca agacttgacc atactcttgt aagactgagc gactgatatc actatcgtct
    20761 gcaaactcgc gcatacgggc caacagccaa gctggatatg ggcttggatg attttcaata
    20821 tccactaaaa tggtcaaata atagcgctcg ttcattttgt agagttcaga agtttccatt
    20881 tcaaaagtca ctgtcttggc aaaagctacc aagtcagcca acttagcaaa agaaaggatg
    20941 tagtagatgt aaggttcttt cttactctca gcttcttgtt cagcttgctc ttgctcttct
    21001 tccttggctt caacttgctc aagagattga atggcttcga tatcatcctt ggttttgtct
    21061 gcgatgcttt tttccagggt tttgataaat tcatctggag acatttgagc caattcttcc
    21121 atatctggca aatccgataa gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc
    21181 acaaagacat ctaccttatc aggttttgga gtcacacgga agctcaacat gcctgtatcc
    21241 agaaagctat caggcatctc tagctcatcc aagatagcat aaaagaactc ttctgttttt
    21301 tcttgaggaa cgagaaagtc agcaatctcc attccacgat ccatcaaatc ctctaaagac
    21361 atcgtgattt ttaaagttgt atcactaatt tgtttcattt tcattgctag taacctcata
    21421 ctttcagttc tatctattat actagatttt tacgatttta tcaaaagaag gctcctctat
    21481 acggatagat tttccctagg gtctttctat aggagactcc aaaagaaaat ttctgcagac
    21541 agatagaaaa agccttcaaa atcggctaag agccgatttt gaagacctta tacatcagaa
    21601 tacttataat ttaaaggttg ctacaccgag gatagaacga tttaagtttc tgagaatttg
    21661 aagactttgc tcaaatttct tataacgagt cactccgtac tcttcaacaa gaaggactgt
    21721 atctctttcc aaaagagatg atacatcctg taaatctaca aaatgcattc cttttaaagc
    21781 ttcttgactc tgtttcaatt tatctaagat agctttattt gagctaacga tggtcaattc
    21841 ctgtccagta tttttgtatg acaaaacatc tgctaggtta gcaattgttg taatctctgt
    21901 tacaaaatca atttgatact gagaaaaatc acctactcta ttgattgttg gattaaagag
    21961 ataaactaac acatttccca tcacaaccaa aatcacacaa accactccaa taacaactaa
    22021 acgaagaatc agatttttca catttaagcc aagcgctgtt tcaccatttg cgttcaattc
    22081 tttagagttg atggtttcca gtttttcaat tttcacattt gcataggcat gtttaaattt
    22141 ctcaatcaac ccatcaattt ttttctctaa caagtcattg gcatctttac ttgatgtcaa
    22201 aattttcaca ccaacccctg catcgtcaat catatagtag acggtcaatt ttttccacca
    22261 atagtcattc gttgaatttt tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt
    22321 tttcaactca ctgggttcta catcattgaa aagataagct ccattcaaat taccatcaat
    22381 caatttccca taaaaatcac tataaccacc aatttgatga ttcaaaatcg ttttggccga
    22441 ctcttttgga ggagtgattt tatagataag ataagttgaa taacttgttg tatctttgac
    22501 agtgttttta ttcctaactg ctttaattgt aaatggtaca gcaatgagag caaataaagc
    22561 gatgagagct aaaatatttg cttttcgctt tttataaaga tttgcaaaca aatcagctac
    22621 tgaataatgt tcaaacatga tttttttctc ctttgtttag tagatactag ttttcctttg
    22681 taagcatttt tgctacaaat ataatcacaa gaacaattcc ccagaattgc attgtaaata
    22741 aattgaagaa actttctgaa aagctgcttc ttggcataaa gaatagatta ttcaagatga
    22801 gtagggataa agcaaatagg attgtccttg agcgataggc tacttgcagc atggctataa
    22861 ataatacgcc gagtaagaaa ctaagcagaa agactccaat cataccatag tcggtataca
    22921 actccatgat ataactactt ccgataccat gccctttcaa gtattccttg ttcaagacaa
    22981 gataggatag attgtgggca taactattac tatcaatagc tagttccaca ctattggttg
    23041 tatgttcaaa ggcttttcct ccgaaaatgg ctcccaaact cccccttgca aaataatcaa
    23101 gaacaggacc aaaagtaaaa ttacggaaat ctcggtaagg gaggctactg ttaaatagaa
    23161 aacctcgagc cagaacacca aaactagtcc cttgtttata gataaagtca agtaagatat
    23221 cccagaaacc tgtatgggaa acttggacat tatcccgtac ataattgagt actcccatcg
    23281 ctaacatgag aataggagaa cctacaaaaa tcgctaactt ttctttaaac ccaatccatt
    23341 ttcctttttc agtttgctcc cgcataaagt aataaacaaa agcaaataaa atacttaaaa
    23401 taaagggatt tcgtgtccca attgccaaat gaatagtatt agctgcaata aaggagacaa
    23461 gcactgctgt ggcctgcaat ttctttggct tggttgccag atacatacac attgcataga
    23521 ccgtaaaggt agacaaaatg taggtaaaat aaggcagttt actttcaaaa tttgcatagt
    23581 aggcatagta ggaagtctgc aaacgataca agagccgttc aaataaccga atgaaataga
    23641 aaggataagt tagaagaaaa actcctagtg atacaaagcg taaccgcttg atataaacct
    23701 cttttagaga atttcctata tttgctactt ttattttctt cctagctatg aagtaacgag
    23761 ccagaatgcc tcctgtggtc aagcccagaa tcgaaatcat gacaactata aaggcaaaac
    23821 gataggctat tggatgatag gtatccaaag caccatccct aaaataatca atggtcggtc
    23881 ttgataccag aaatacaaaa atggttaaat agaaaataaa atggattaag taatacttga
    23941 tatcattcca acaagcaatt aagctactaa ccaacaagaa caataaagta gaaagtaagc
    24001 taacattatt attattaaac agatacacaa ttccacttac tagcgtcaag gcataactga
    24061 ctatggtcaa actaaataat aatcgtttcc catcaatcac ttggtcaccc ccgttctaat
    24121 gtaatttttt agatttttca atatttttca gtaataagaa tcgatataag gaaatattta
    24181 tgaatagggc caaagcacta attcttctcc ccttacggaa aattggattc ctagaaatag
    24241 caaaggcatg gccttttaaa aaacgatgaa tctgagaata ggcttcaaac tgtttatact
    24301 gatcatctag caacatctta tccagaataa agaagtgggc ataggccaat ctgaaaaaag
    24361 cgacctcttt caagtcagga tagtttttca caacttcatt ataaaacttt tggtagatat
    24421 caatataggc taaatccttc tctgcatagg gtttggtcgt aatactatcc cctctatgga
    24481 aatagtaata atagggttta gtattaacca catacttctt ggccaacttg attaaatcaa
    24541 aatggtaata ggcatcttcg taaatcaacc ccttaggaaa ggatagggca gttgcaatct
    24601 gtctcttgat tagcttattg caaatcgtcc caggtatttt ttcacctatg aggtattcct
    24661 ttagaaatgt ttgagaatca cagacaaaat agtcatcctg attggctgac tgtgggcttt
    24721 catcattagc atagacattc atgacaccac agctcgaaac atccgcatct tcttgaacta
    24781 attgctcata taagctctga atcatttctg gatggatata atcatctgag tcaataaaaa
    24841 tcagataatc cccgtgagcc tgcttcatcc catcatttcg tgcttgcgac aatccttcgt
    24901 tctttttatg aagcactgac accctgtcat cttgttcagc gattgaatca cacaagcgac
    24961 cactttcatc tgttgcacca tcatcaacaa gaataatttc cagattttga taggtctgct
    25021 tctgaatgga agctatcgat ttttctaggt actgcgccac attatagact ggcacaatca
    25081 cactaattaa tgcagtttcc atgctactcc tctaatagtt tttctacttg ttcgatttgt
    25141 tttgtaattg taaattgttg aatgaattgg ctagcctcat cgacatcaaa gtttgaggca
    25201 gaagtcatgt aattagtaat cgcctgagct gcctcttgat tgctctcaat gatttgtcca
    25261 aatcgtcctt cttgggataa ttcctcagcc cctccaacgt ccgtagagat aaaagggagt
    25321 cccagactca aggcctccac atacactcca ggaaaacctt cttgtttaga catagacaaa
    25381 agaactttcg tctgagatag atactgataa ggattttttt gataaccaag gaaatgtaca
    25441 tagtcctcaa tcccatactc tttgactcgt tttttcagtt cctcttccat atcaccagcc
    25501 ccgataaaat agagatgata gttttttccc tcttggtgta ataatcgtat cacttccact
    25561 acacggtcag aacccttatt ttcctcaatc cgtccgatag tacagatact ttgaggagca
    25621 atctcgatat cgatcttctc ttgagatttt tctagaatag tctgaaaatc atatccattg
    25681 tagattgtct gtaatttaga agtataatct ggataaactt ccttgataga attgctggtc
    25741 ttttttgaaa tccctacaat tgtattcgca gcatccaact ggcttctatg tgattctctt
    25801 ttagagctat ccttaagaag ttcttcaata cttccatgaa tccaagatat cttcttgact
    25861 tctcttcttt tagagaacaa cagtggtgga ttcataatgg taaaagaaac ttcaacatca
    25921 taatcatctt ttacaagcaa acgacgagtc agtcttggaa aataaattct cattctccac
    25981 aaaaaagctc gtaaccatct ggtttggcga taatcttgaa gggattttaa aatgcgtaca
    26041 tgctttggaa cagattcata tcccttgtca aagtgctcca tttcaagaat atcaatatca
    26101 tacttttctg gatccagatt tgaaacaatg gttgatagaa tcttctctgc accacctcca
    26161 agagaaaaag accacataaa aaataagatt tttttcttag ccaccatatt ctcccttgta
    26221 ttctgtataa gacttatcca tatcagcgat gacagcatca tgatgcggta cctgcttgtc
    26281 tgctggtgga ggcgtcatat aatccccaaa agcagttctg agatagacat catagccgat
    26341 tggaataggc atctctgttc cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat
    26401 tgggtacttg tttctcatgt agccaggacc tgagcataat tctgtaatgc catcacaatc
    26461 agccaaatca tacttagtca tttctttctc agcttttttc cagatgcgat aacggagaga
    26521 ttttggagtc aaacccagta aaatgcgact tccccatttc atgagagcac catgcttttc
    26581 tggaatagtt tgcgcacaaa agagtgaata aatcaaggcc caacgaacct gttttttccg
    26641 ctcagctgga tttttcggat aataatccaa aggcaaaata tccaaggcca gaccatgtgg
    26701 caaatccaaa tcctgctgat aaggcttgat acaggtggtt tccttgtcac gaatggtaat
    26761 aaaaagatta cgatcaacaa aatccttgtg actctttgac aagaaataac gttcatctgc
    26821 ataacgaggc cataattctg ctaatttctc ataatcttta cgaggcataa aaaagtctag
    26881 gtcgtcgtcc caaggaataa atcccttgtt tcgaagggca ccaatagcgc ctccgccaca
    26941 gagataacag agcaaatcat gttctttaca aaaggccaca aaatattcag ccatctccag
    27001 actacgagcc tgaattgctt ttaaatcagt catattgttc attattcttt ctatcgtatc
    27061 gtttcattat accacaaaca aggggtgaaa atctattgca gactgtaaaa aatcaaagcc
    27121 tgactgctat ccaaatagct atcaaacttt gatttttctg tcttatactc ttcgaaaatc
    27181 tcttcaaacc acgtcagctt caccttgccg taggtatagg taactgactt cgtcagtctt
    27241 atctacaacc tcaaaactgt gtttttagca gcctgcggct agcttcctag tttgcacttt
    27301 gattttcatt gagtattatc ttatctcaag cccatttgag cgagcttggt ttgatatttg
    27361 ttttgatcaa ccagcaagcc caagcctcca taaacatcat aggcatctac ccagtcaccc
    27421 agttctggaa tcgtcaattt ttcaatacca ttttttgctc catccaaaac agataaaccg
    27481 tttgttagga ggaaagtata gggtacgttg gttgaggtca tagcaaaaac ctttccaaga
    27541 gcttcagaac cagtgaaaag tttagtggga tctttaattt gctctaaaat tgctgttaaa
    27601 acttgttgct gtctttttgt acggccgtaa tccgcctcat catcatcacg gaaacgagca
    27661 taattgagca gggtcgagcc attcatctgc tgttttccga ctttaatggt ttgggttgga
    27721 gactcagtct cggtagcata taaatcatct ccgactgtag cttctgttag gggacgccca
    27781 ttcaatgttg aaaattgagc atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct
    27841 gtggcaaagg cctggaaatc aaccaaggcg tagtacttaa tgtccaagtc aaaattatct
    27901 ttcaagactt ggcgaaccat ttctgcccct ttttgcccct cttgttctcc taactcgtag
    27961 gctacgttta acttgttatc tgtctgtttt ctaccgttaa tcacttgact ataaccatct
    28021 atatagacca aattatcacg catgaaactg actagcttca ttttcttatc tgagcccccg
    28081 acatttaata ccataataga gtcagttcgt gtctcaacac tgttctggcc gattcgacca
    28141 tcagtaccca tgattaaaat attaactcca tctctagtgt cctgaccatt aaagacttct
    28201 acttgagctg cccgggcatc agcagttttc tttgcgctag catcttggta accacgcaaa
    28261 aacatgaata ccatggccaa agccacacag accaaaagtg aaaaaatcac cataaaaatt
    28321 cgtttaagac ggagcttccg tcttttcttt tttggaggga aagagagtgc ttgtgatttg
    28381 gattgtgagc gactccggtt cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt
    28441 tccaagctag agctactatt tcccctagca agagttagct tttcttgcaa ataggcaaac
    28501 tcattttttt ctctctcatt gaggtagtga atatttttta gcaaataatc ataacgcaac
    28561 tgctcatgat gacttaaggg attttcttta ctcatcttct ctcctttcca tggtctgata
    28621 ttggataaat aggataggca cccagaattt tatactggat tccaatcgct tctaattctt
    28681 tttgggcaaa gtggaccaag tccttatcgg tataatccac atcgataatg aaaaagtatt
    28741 cacccagtgc tgtcttgagt ggacgacttt caatttttgt caagtcaatt cctcgccaag
    28801 caaaggtcga cagggcctta taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca
    28861 aactcatctt ttcagtttgt gcttgcaagg gaatactagg cttttcagct cctagaaccc
    28921 agaaacgtgt gaaattggct tccatttcct gaatatcctc ggcaatcagt tccaatccat
    28981 attcttcagc agaacttcta ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa
    29041 taaaacgggc cgcataagct gtactagctg ttacctcgat ttgagcctct ggatattgtt
    29101 catcgatgaa tttctttcct tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct
    29161 tagtatggcc tggaaccacc atcaactgct gatgaatagg ctgaacgatt tctgctactg
    29221 cttggatgtg agcctgatga aaaagatagt ccaaggtttc atgaacacta ccctcaatag
    29281 aattttcaac tggcaccaca gaatagttca ctaatccttg ctcataagct ttgatgacat
    29341 ctgtaatgtt ggcaaaagcc tgcaattcct catgaggaaa agctgtctgc acaacgtggt
    29401 gtgaaaatga tcccttggga cctagataag ctattttcat cttagttcct ctataatttc
    29461 ctctgggctt agcttggtca catccaaaac ccgactagcc acttcctcat accaagcctg
    29521 tctttcttga aaaatagcta ctagttcttc cttgctatta tttagaaaaa gcggtcgctg
    29581 attgtcctta tcagctgcga tacgtaggta gagggtttca aaatctgctt tcaggtagat
    29641 gttatctgta ttagtcttga gtaagtcacg atttctctga gaaataacca ctcctcctcc
    29701 agttgacacg acttggtctg tttgtagtaa atcagctagg acttctgatt ctacatgacg
    29761 aaaggctgct tctccctttt cagcgaaaaa attcgcaatg gacataccta ggcgcttctc
    29821 aatcagagca tccatatcaa ggtaattagg gtccaagcct cttgcaatag tcgattttcc
    29881 agcccccata aaccctaata acaccttagc catgaatcaa gctctccaaa tcatcaaaga
    29941 aactaggata gctggtattg atggcttctg cacggtcaag ctccacctct ccatctgcaa
    30001 ccaagagggc tgcgatagct gtcatcatgc cgatacggtg gtcaccaaac gtattgactc
    30061 tagcaccgtg aagagctgat ttccctttga taatcatccc atctgccgta ggagtaatat
    30121 ctgctcccat actatttaag gcgtctgcca caacctgaat acggtctgtt tccttgacct
    30181 tgagctcctc agcatccttg ataactgtta caccttgggc ttgagtcgca agcagggcaa
    30241 taatgggcaa ttcatcaatc aaacgtggaa tcaaagcgcc accaatctct gttcctttca
    30301 agtcagaaga ctcaacaatc aaggtagcag atttagcgac tggatcgatt tcagttattt
    30361 ccaattttcc acccatggca cgaatgacat caataatacc ggtgcgagtt tcgttgatcc
    30421 ccacattctg cagcactaga cgagaatttg gaacaatcaa acctgcgacc aaccaaaagg
    30481 ctgcactgga aatatctcct ggaacaacca ccttttgtcc tgtcagtttt tgaagtcctc
    30541 ggactgtgat tttcttgcca tccacactta aatgagcacc aaattgttgc agcatatctt
    30601 cagtatgatt acgggtgcat tctttttcga taatcactga ctctccctga gcctgcaagg
    30661 ccgcaaacat caaggctgac ttgacttggg cagaggcaat tggcaactca tactgaatag
    30721 gtgctagttt tttcgtccct tttaagtgaa ggggaggcaa gtctcgctca gtttgccctg
    30781 aaatgctaac gcccattttt ttcagtggaa tcgtcacacg gtccatagga cgtttggaaa
    30841 gactatcgtc tccgaacatt tctacttcga agtctgcacc agcaaggaca cctgaaatca
    30901 ggcgaatcga ggttccagaa tttcccatat caagggcatt ttgtggagct tttaggccgt
    30961 ccataccgac accttgaatg gtaacaaccc catctttatc ctcaatctct acaccaagat
    31021 cacgaaagac ctgcatggtt gaaaggacgt cttcaccccg caaaatatca taaaccttgg
    31081 tctctccctc agctaaactt ccaaagataa tggaacggtg gctgatagac ttgtcacctg
    31141 ggacgcggat actgccatgt aagtggctaa tgtttgtttt tagtttcata ctggacctca
    31201 tacttgcaat acttttacct attttatcat aaaaagccag aaattcctta aaaattcctg
    31261 actttaggat agttattttc ttattttagc aattctgaaa ctggttcgaa aacaattttt
    31321 tcaatgtcag aaaggtaaat ggccaattgt tgttgcttag taaagaattc tgacaagagg
    31381 ctatttcctt gaatctgctt gccaaagcct tccatcttag cttggaagga cgcatctggc
    31441 atttgacctg tctgtgctag tttttgaatt tcctcttgaa aggcaagata atctgtaaag
    31501 attttgcttg cctcagcatc tgctgcaatc gcatctttag ctgctttgac agccttgtat
    31561 tctggtaatt cgcgtagacc gcgactaagt tcgtttgcac tatcgtaaat atttgacatg
    31621 attttctcct tatttgacaa cgactgtgta gtcggtattt tctgttatga gatgctcagc
    31681 tctttccaag tcttgagcat ttttaaatga aatttgtaga atcccgtgaa tatcctcacg
    31741 gttttcctcg ttgatatgaa tattgaccaa ggaagttcca cgtagtagtt ccaaaatcct
    31801 caagatgaca tcttcttcat cgggaacgtc gacatagagg tcgtaagaac tatccacacc
    31861 tccacgctta tggatttcca tggcctgacg ttgttcacgc gcttggttaa aaaagttcca
    31921 aatttgctct tcatctccct tactaatggc ctgaccaatc gcttccaaac gttccttgaa
    31981 atcctcaatt ctatccagaa tgatctcgct attggacaag agaatggagg tccacattcc
    32041 tggctcgctt tccgcaattc gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc
    32101 catctcatgc tcttgagcat agaccgcagt ctgctccatg agactagaag ccaaaatatg
    32161 aggaaaatgg ctaatctgag aagtgacacg atcatgctcc ttggcatcaa tctcgataaa
    32221 acgagcatga agacctgaaa gcagatcctt catttcctta agcgtgtcct gacttgtcag
    32281 gcttgaaggt gtaaagatat aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc
    32341 ccctgtcttg tgactaccag ccatgggatg ggccccgaca aagcgaacag acttgccagc
    32401 caaatactgc tccgccgcat ccacaatggt tgacttggtc gaaccagcat ctgaaataat
    32461 aacgccttct cgcaaatcca aattggccaa ctccttaatg aaagcaatag tttgtttgat
    32521 tggcaagctg aggataatga catctgccaa aggagcaaaa ctagcaaaat catccgttgc
    32581 acggtcaatc ataccttctt tcaaggcgat atctctcgaa gcttgactac gattataacc
    32641 taaaatttca taatctggat gatcgcgttt gataccaagt gccatagagg ctccaatcaa
    32701 cccaagacct gcgatataga ttgtttttgc cataggaact ccttaatagt tctttgtata
    32761 gtctcggtgt ttggctaccg cttcttttag ttcctcaaga ttatctgatg agaatttttc
    32821 gaggatttct tgcgccagaa ccgttgctac aactgcttcc atgaccattc ctgcagctgg
    32881 aagagcagtc ggatcacttc tctccacggt tgccttgtaa ggttcgtggg tttcgatatc
    32941 cacactcata agaggtttat aaagagtagg aatgggtttc atgaccccac gaacaacgat
    33001 gggttgccca ttagtcatac caccttcaaa accacctaga ttattggtac ggcgagtata
    33061 accgtcttct ttagaccaga gaatttcatc cataacttgg ctgcctttac gataaccagc
    33121 ctcaaagcca agaccaaatt ccaccccttt aaaggcattg atagagacaa cagcttgagc
    33181 caatcttgca tccaattttc tatcccattg gacataggaa ccaagaccaa ctggaacgcc
    33241 tccgacgact gtctccacaa ccccaccgat ggtatcacca tcacgtttga tttggtcaat
    33301 atagtccttg atttcctgtt ctcgttcttg gttgacaata gaaacttcag actgggcagc
    33361 tctttgctta atttcagcga ctgtcagatt ttcaggaaca tctatttcct taccaccaaa
    33421 gaccacgaca tggttggcaa tctccatatc cagctcagcc aagaggcgtt tggctactgc
    33481 accaactgcc acccgcatgg tggtttcacg agctgatgaa cgctccaaag aatttcgcaa
    33541 atcatcaaaa cggtacttaa tccccccaac caaatcggca tgacctgggc gaggatgagt
    33601 aattttccgc ttgcttttaa ggcggtcttc aatgtcctcc gcagacatga tgtccagcca
    33661 tttctggtgg tccttattga tgacatccat agtaataggc gcccctgtcg tcttcccgtg
    33721 gcgaacaccc gaagtaaaga caacctggtc actctcaatc ttcatacgac caccacgacc
    33781 gtagccaccc tgacggcgtc taagatcctc attgatatcc tcagctgtca atggaagtcc
    33841 agctggaatt ccctcaataa tagctgttag acgggggccg tgtgattctc ctgcagttaa
    33901 atatctcata cactctcctt attttaccaa gtagtctttc atctcttcca gagaaactgg
    33961 gtgaatggtc gctgaaccaa gctctggcac caagaccaat ttcaaggtgt taccacgcgc
    34021 tttcttgtca tgagtaagag cctgataaag cttgtcaact ttccaatttt catagtcaac
    34081 aggcaagccg aatttctgac acatctctgt gatagattgg gtaatgccag ctggcatgag
    34141 gcctttttcc tcagcaacct tggaaatctg taccattccc atggcaacag cctctccatg
    34201 catgaccttg ccataaccgg cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt
    34261 gaggtaaaga cgaataccat tgtccaactc atcttcaacc accatcttgc gcttcacctg
    34321 acaagaatgt tcaatcaagg tctctgcatg ttccaaaata ctctcaacag aaccattcag
    34381 tcccgtcaag agagcccaca gttctggatc ctcaatcaag ccatacttga taacttcacc
    34441 catcccttca atcaactctc tttttccgag ggtttcaaga acaagtggat caatcagaac
    34501 cccatctggt tgggcaaagg tccccaccat atttttagca aatggtgtgt taacgcctgt
    34561 ctttccaccg atagaagaat caacctgagc tgtcaaacta gtcggaatct gaacaaagtg
    34621 aataccccgc atataggtag aggctacaaa gccagccagg tccccaacaa cgccaccacc
    34681 aagagcaacg attccatcgc tacgagtcag accttgcttg actagaaatt catagacttt
    34741 ctgaacagta gttaaattct ttctttcttc accttctaag aaatcaaaaa cagctacctg
    34801 aaaaccagca tcttctaggc tgagcttgac cttctctgca tagagagagg ctacatggtt
    34861 atctgtcaca atgactacct tttgcggttg ccagagttct cgcaaccact gaccagcctg
    34921 ggccatacaa cctttttcaa tctgaatatc ataaggatga tgaggaatat cgattctgat
    34981 tttcatagga gagtctccct ttctttattg gtatttttct gttaaagact gccaaatctc
    35041 ttctgtcggc atttccttgc ctgtccacag ttgaaaagct tctgcagctt gatagagcaa
    35101 cattcccaga ccattgactg ctggattgcc ctgacttcta gcccatttca aaaacggtgt
    35161 ttcaaagggt tggtatatga tatctgcaac taagagagtt tctggtaaga ctatgttttc
    35221 aggaacagga gaggattggc catccatgcc cacactggtg gcattaacta gcaaatccga
    35281 ctcggcaatc cttgcttgca gttcagaaac atattctaaa gcacacaaat ccactttaaa
    35341 gcctgtctgc tcctgtaact tgtctaggta aggtcttgtt ttttccatag aaacggaacg
    35401 aacaaagacc gaaatctgac tgacgccatc caaaatagcc tgtgccaaga ttgatttagc
    35461 cgcaccacct gcacccagca gggtcatctt tttacctgaa attgtaaaag aaggcaagca
    35521 cttaaaaaat cccttgccat ctgtattata tccaattaaa ttgccattct cattgacaac
    35581 cgtattaacc gcaccaatca agcgcgcttc atcgcttagc tcatccaaat aaggaatcac
    35641 ctgctcctta tagggcatgg acagattgat gccaaacatc tggtagcgac gaatattggc
    35701 cactgtttct gccaagtcac tcgcttcaat ctcccaagcc acataagcac cgttggtagc
    35761 tgtcgcctca aaggctctat tgtggatgaa gggagaaata gaatgcttaa taggattggc
    35821 aacaactgca gctaaacgtg tatagccatc aagcttcatc caaaatctcc ctgatttttt
    35881 tcatgctagc tagagaaatc tgcccagggg cactaacctc atccagactg gcaaaagacc
    35941 aactcgaacc agtcacatcc gcagtgatac gagagacctt gcccacctta cccatagaaa
    36001 tggtcacata ttcctgttca ggattgaggg ttttaaagcc tcgtgtatag ttcatcaagt
    36061 ctaagacatc ctgctccgtg tgagccatca ccgcaacctt aacaagtttt ggatttagga
    36121 tcgtcaactc tgacaagatt tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac
    36181 tcaaaacaag atttgggaag tccagcattt cctcaaaaac atccttgtag ctatagtact
    36241 caaaatcaat atagtctggt tgatagagtt gcgcaacttc cttgattaga tggatatact
    36301 cttctggaga aaggtcgatt tctccacctt cggagcgagt tcgtagcgtg aaaaccaact
    36361 cacggcctgc gaatttttca aaaatggctg gagctacctg caaaatcgct tctttaggca
    36421 gatagtcggc acgccattca atgatgtcgg catccaggta cctcgtggca tccagagcct
    36481 gagcctcctc taaacttctt ggcattactg aaacgattaa tttcatttac taaccttcat
    36541 actaatcacc ttgaggtaat tactactttc atctttttta ttataggcaa aatctgctgg
    36601 aagaccatat ttgtttaaaa tctggtaact tcttcctgca aagcctttat caatttgttc
    36661 tgtaaatttc tggcgggaaa cattggcagc attggtactg gcaatgataa tccctcccgg
    36721 atttaaaatc tcaagactct gggaaatcaa cttgtgataa tccttggcca cagagaaagt
    36781 ttgtttttta ttccgagcaa agctaggcgg atctaggaca atcacatcgt aggtcaagtc
    36841 tttgcgtttg gcatatttga aatactcaaa gacatccatg actataaaac gatgctcgtc
    36901 tgtgctgagc ccatttgcct gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag
    36961 atcaacagaa gttgtctggc tagctcctcc catggccgca gctactgaaa aagccgctgt
    37021 gtaggaaaac atattgagca aggatttacc catagccaag ccgtcaacta aactaccgcg
    37081 aacctcatgc tggtctagga aaattcctgt catcaaacca tcattcataa agacttgata
    37141 caggacacca ttttctaaaa cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc
    37201 agattcatag tccaaacctt taaagcggat tttctcataa gcccctaaaa cctcagggaa
    37261 aacctgtcta aaggcttctg atatagtctg acgaatctga taaacataag agttatacca
    37321 agaaaagacg gcgtagttgc cataaaggtc cactgtcaga cccccaaagc catctccctc
    37381 ttgattaaag agacgatagg tagttgttaa atcatcttga tagtaggcgc ttctcttttc
    37441 tttggctttt ctaaacaacg tttcaaagaa agcttgattg aaggccacct tgtctttgct
    37501 gacaaaccag cccaagccct tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc
    37561 ttcctgaccc tgcacctcta cttcctgatc cttaagattg acattctcaa gatcactggc
    37621 ttctagtaaa actagcccct tagcaagctt cttttcaacc cttttgctga ctcttattct
    37681 attcataact accattatat caaactttta gacaattctc aaaaaagaaa ctacccttgc
    37741 ttttttactc ttcttttaaa aaatggtata ctagacttcc tgcaaaacta ggaagtaaat
    37801 gtgtaagaat cacaataaaa aatgctcttc cgtcttggag gagcattttt tttatcaacg
    37861 aaaatcaaat agcaaactat gaaactagcc tcaggttaac tgtgatatta taggtagaga
    37921 ggttgtatca gcaatatgtg tctgtcaaat ttagtgacaa aggtagtaga agaaagatga
    37981 ataaataaat cagcttcagt agatatctgg aaaatttgat tttatagaga agccttttgt
    38041 tacaaactca atatactatc aataaataat attatagaag caacaataat tataatttca
    38101 cctatctgca tcattctatt tcgaattcta aatatatgtt ctatcaagaa tacttggaac
    38161 acacacatta taggaattaa cgtttttgaa attgaaaaat atccaaataa ataaactata
    38221 aacaacaaaa atagaactat gttatatttc ttattcaaaa cattcctccc tatatttttg
    38281 attaccaatc ttaatcattt acaactacat tctaacaaac tataaaagcg tttgtcgaat
    38341 tgaatttatc aagcaagcga ccaaccagct catctttttt ctatttctgc caatatgcgt
    38401 gacaggtaat aatgatagcc aaaaatagca agagcaagca ggaggataag agctcctact
    38461 cccaagctga tggcaaggat agtggagaga gactgaacca agaatatgct cccaattaca
    38521 agggccatca ggattgcact ataaataaac aataaaacta tggcgactat gccatttgaa
    38581 cgattcacca ggtccgtaat gctactccaa ttggttgaca gatttttaac gtccttaaag
    38641 taatggtggc aagaaaggat gacactggca aggatccatg ccacaataag gtaaatcatc
    38701 gaaatgatgg gcaagcctag atatagagaa agaccaagca aagtcagaac tggtaaaaag
    38761 gactggacag catatataat ccaaaatttc actttcacat aacgagcaaa gtcaaagggt
    38821 aaactcttaa gaaaatcaac attttccctc tccaaggaca aggcaattga atgcaggctg
    38881 gtgatattgt tattgacaac tgctataaag agagctataa aaaacaaggg taaccagtat
    38941 ggaggatgaa tgtctggaac tatctgagaa tctcggattt tggaaatcag accgatcatc
    39001 atgagataag gaaagaaagc acttgtaaaa agcactgtaa ccacgccagt accctgtccc
    39061 aagagggtga ggtggtagcg taaaaccatg cgaaaaaatc cctttttagt ggttgaaatt
    39121 ctctccttgc tgcgacgttc ttttttgacc ttatcctcac tattaagcag gatcacgtca
    39181 taaaaacgag gaaggacctt ctttttggtc agataaagca ggaagagagt tagtcctatc
    39241 caagcgagca gacccactaa ggcttctgtc gaaaaaggct ccactgctat tttgtaaaag
    39301 atatgaagag gataaaggag aaatggaatg tctctaactt tgtcaacaat acttccaaaa
    39361 gtcgactgaa gaaagaagat aaatattaaa ggtatgagaa ctcctatccc aatcatcaca
    39421 ttcgaaaaaa tagactgata ctttctgaag accctagtct gagccaagaa atgtactgcc
    39481 actaccatca ctaaagtaac agagacaaat aataaggtca aggacagtag catcaaaggc
    39541 aaacccaacc acagagaagg tgctagccta atgtatagga ccagaaaata agctaggatt
    39601 ggtacaattc cagctagagc tggcaagagg acagacagac ctttggccat tataatctct
    39661 gattctttaa aggcataggg cctataggag gccaggtcct tactctcata aaagacattg
    39721 taaaatgcag tgaaagaagt tgaaaaggcc agcaccagta aaatagcaac catcgtacta
    39781 aaaaaacttg gcatttcctc aaaaggaaaa cgaaaggcta tatttataaa catgaaaagc
    39841 atcaagagac tggaaaaaat gtaagaactt aggactctag cggaaacatt tacttttttt
    39901 ccagtatttt tagcttgctt ctttcgtagg ttagccagat tagcttcttg agatgaatag
    39961 aggatattga tatcaactaa ttttttaatg accttgagac gcatctgaaa cctcctcttt
    40021 tctaccagca agactaaggt agatactttc caaagactgg tctgggtaat cttttctcaa
    40081 gtcctctaca ctaccacaat aaatcaaatg cccctttttc aaaatggcaa tccgatcaca
    40141 gacttgctct gccacctcta ggacatgagt tgaaaacaag actgtcttcc ctttttgtgc
    40201 atgttccttc atcatctgtt tcaaatcaaa ggcagcctgg ggatccaaac cagtcaaggg
    40261 ttcgtccaag acccaaatat caggatcaga caagagtgcc ccgatgacaa aaactttctg
    40321 acgcattcca tgagaaaagg tttcaataac ctgataacga ttttcagcaa aatcaaaaac
    40381 gttcaatagc ctagctagac tagtctccaa gtcagagcta gtcagatcat aggatgaggc
    40441 gatcaattcc caaaattcat tggccgttaa acgtaaaaat aagtcaggcg agtctgctac
    40501 gtagccaatc tttcgtttga tcgccaagcg attttccgat aactcctgac catctaccaa
    40561 aatacgacca ctgctgggtg aaatgatact gactagggat tttatggtgg tcgattttcc
    40621 agccccatta tgaccaatca agcccataat ctctccattt tcaatctgca aattgagatt
    40681 actcaaggcc tctttatcac catacaactt actaacattt tgaaattcaa tcatgggatg
    40741 actcctatct ttatctgtat tatacatcgc tatactagca ctttgataca aaaaaatcaa
    40801 tactttattt taagtagtta aaatagtttc cttctatctt acgcaaacgt ttgctccgag
    40861 agatacttta tgatagaata aagaacaaga ttgacaagta agaggaaaca tcatgcaaaa
    40921 tcaaacactc atgcaatact ttgaatggta tctgccccac gacggtcaac actggacgcg
    40981 tctggctgaa aatgctccac acctagctca tctggggatc agtcacgtct ggatgccacc
    41041 agccttcaag gcaaccaacg aaaaagatgt cggctatggg gtctatgact tatttgactt
    41101 aggagagttc aaccaaaaag ggactgtccg caccaagtat ggtttcaaag aagactatct
    41161 tcaagccatt caagccctta aagcgcaggg aattcaacct atggccgatg tagttctcaa
    41221 ccacaaggct gctgctgatc acagggaagc ctttcaggtt attgaagtgg atcctgtaga
    41281 ccgtacagtt gaacttggag aacccttcac catcaatggc tggactagtt ttaccttcga
    41341 tggtcgccaa gatacctaca atgacttcca ctggcactgg taccacttca caggtacaga
    41401 ctatgatgcc aaacgccgta aatccgggat ttacctaatc caaggagaca acaagggctg
    41461 ggctaacgag ggattggtcg ataacgaaaa cggaaactac gactacctca tgtatgccga
    41521 cctagacttt aaacatcctg aagtcatcca aaacatctat gactgggctg attggttcat
    41581 ggaaacgact ggtgtagctg gtttccgttt ggatgccgtt aagcatattg actctttctt
    41641 tatgcgcaat ttcatccgcg atatgaagga aaaatacggt gacgatttct atgtttttgg
    41701 tgaattttgg aacccagaca aggaagccaa tctggactat ctcgaaaaaa cggaagaaca
    41761 ctttgacctt gtcgatgttc gtctccacca gaatctcttt gaagccagtc aagctggcgc
    41821 aaactatgac cttcgtggca ttttcacaga tagcctggtt gaactcaagc ctgacaaggc
    41881 tgtgactttt gtcgacaacc acgataccca acgaggacaa gcccttgagt ctaccgttga
    41941 agaatggttc aagccagcag cctatgccct cattttgtta cgccaagacg gccttccatg
    42001 tgtcttttac ggagactact atgggatttc aggccagtat gctcaagaag atttcaaaga
    42061 aatccttgac cgcctcctag ccatccgaaa agatttggcc tatggagaac aaaatgacta
    42121 ctttgaccat gctaactgta tcggttgggt acgttcaggt gctgaaaatc aatccccaat
    42181 cgcagtcttg atttcaaatg accaagaaaa cagcaagtca atgtttgtcg gtcaagaatg
    42241 gactaatcaa acctttgtag atttacttgg taaccaccaa ggtcaagtta caattgatga
    42301 ggaaggttat ggacaattcc ctgtctcagc tagatccgta agtgtctggg cagtcaatac
    42361 catctaatag ctcataataa ccaagctagg tccaagcgga tttggctttt ttgtagtcaa
    42421 aaaagaccta cccaaatgga tagatcttta cttgattaca atttacctgc tactgcatcc
    42481 aataattctt ggatcttagc ttggttgctt cctcctgcca tggccatgtc tggtttacca
    42541 ccaccacgtc catcgatgat tggtgctaat tctttgacaa ggtttcctgc atgaaggtct
    42601 tttgtcttgc ttgctacaag gacattgact ttgtcaccga tagcggcaac taggacaaga
    42661 agatcagagt agtctttttg tttccagtta tctgcaaaag tacgaagggc accggcatcg
    42721 gatacagaca cttgactagc aatgtaacga tgaccgttga cttccttaac atctttgaag
    42781 atatcgcctg cggctgcagc tgcggctttt tctttcaact cagcattttc tttttgaagt
    42841 tgacgaagtt gttcttgaag tccttctacc ttgtgaggta cttccttgac ttgaggtgct
    42901 ttcaaggttg ctgcgatagc tttaagagca tcctcttgtt cacgataggc ttcaaaggct
    42961 tccttaccag tcactgccaa gatacggcga gttcctgaac cgattccttc ttctttgaca
    43021 attttgaaga gaccaatctc agaagtgttg tcaacatgag taccaccaca aagttcaata
    43081 gagtagtcac cgatagtcac gacacgaact tccttgccgt atttctcacc aaagagggcc
    43141 atagctccca tttctttagc agtgtcaata tccgtttcaa ctgtcttcac ttcaagtgct
    43201 tcccaaattt tctcgttaac ttgctgttca atcgcacgaa gttcctcagc agttactgct
    43261 tggaagtggg taaagtcaaa gcgaaggaat tcaacttcgt taagagatcc tgcctgtgtt
    43321 gcgtggtttc caaggatatt gtgaagggca gcgtgaagca aatgagtcgc agtgtggttt
    43381 ttcatgacac ggtgacggcg attgctatca attgccaagg tatattcttg gttcaaggca
    43441 agcggtgcaa ggacttcaac tgtatgaagg gcttgaccat ttggggcttt ctgaacattg
    43501 gtcacagtag ccacaacctt acctgactca tccaagattt gtccgtagtc agctacctgt
    43561 ccacccattt cagcataaaa tgacgtttcc gcaaagataa gagaggcagt tccttctgaa
    43621 acagctccta cttctgcatt gtcagcaacg atagctacca atttagaaga caattggcta
    43681 gcattgtagt tgaagacact ttctacagtg atgttttgaa gagtttcatt ttgcataccc
    43741 attgagccac ccttgacagc tgacgcacgc gcgcgttctt gctgttcttt catggctgct
    43801 tcaaaacctt cacagtctac agtcatacca gcttcttcag caatttcttc agtcaattca
    43861 actgggaatc cgtatgtatc atagagttta aagacatctt gaccagcaat gacagattga
    43921 cctttttctt tcaagtctgc cacaatgcct tgggcaaagt gttgacctga gtgaagggta
    43981 cgggcaaatg attcttcttc gctcttaacg attttctcaa taaagtcacg tttctcaagc
    44041 acttctgggt agtagctttc catgattttt ccaacagttg gaacaagttt gtaaaggaaa
    44101 ggctcgttga tacccaattt ttgaccatgc atagaagcac gacggagaag acgacgaaga
    44161 acataaccac gaccttcatt tcctggaagg gcaccatcac cgatagcaaa tgaaagagaa
    44221 cgaatgtggt ctgcgataac cttgaagctc atgttgtcgc catcttggtc ataaacctta
    44281 ccagacaatt tctcgacttc acggataatc ggcataaaga ggtccgtttc aaagttggtc
    44341 ttagcccctt ggataacagc caccaaacgc tccaaaccag cgcccgtatc aatgttctta
    44401 tgtggcaatt ccttgtattc gctacgagga acagcagggt ctgcgttaaa ttgtgacaaa
    44461 acgatgttcc agatttcaat ataacggtcg ttttcaatat cttctgcaag caggcgaaga
    44521 ccgatatttt ctgggtcaaa ggcttcccca cggtcaaaga agatttctgt atctggtcca
    44581 gaaggtcccg caccgatttc ccagaagttg tcctcaattg gaatcaagtg acttggatcc
    44641 actcccactt caatccagcg gttgtaagaa tctttatcgt ctggatagta ggtcatgtaa
    44701 agtttttcag cagggaaatc aaaccattca gggcttgtca aaagctcata agcccaagtg
    44761 atagcttcgt cacggaagta atccccgata gagaagttcc ccaacatttc aaacatggta
    44821 tggtgacgcg cagtcttccc tacgttttcg atgtcgttgg tacggatagc cttttgggca
    44881 ttggtaatac gtggattttc agggataatg gtcccgtcaa agtatttctt aagggttgct
    44941 accccagagt tgatccacaa aagagttggg tcatttacag gaaccaaact tactgatggt
    45001 tctactgagt gacctttggt cgcccagaaa tcaagccaca tttggcgtac ttgtgcacta
    45061 gatagttgtt tcatattgtc tccttattca cttgtttaat gtgattggct ttccagcatt
    45121 tccacatagt caatcgcgac acagagggaa atgactaggt ctgcataagc gtcctcaaga
    45181 accgttacgg tataggtaga ggtcagatgg aagagttcct tcttaatttc cgcaatcaac
    45241 tgatcgcgat catccagcaa tttgaaattc aaatcccaga tattgccctc gatacgaaga
    45301 cctagattat caaactcata cttatctcgc caaaaggtca acttcttacg aatgacaaaa
    45361 ctcgagccat cccgaagctg aatctcaaaa cgaggaagca aggtcaagat ttctttactg
    45421 atctgactga cttgttcacc agccgcatca tagatggtaa aagttttggg aatcttaaaa
    45481 aatgatccct ccacctgata ggcaatttct cccctgtcat ccttgatagc gaagcgttcg
    45541 cctccaagac gaaacttttg tttgacaaga aatgttttca tcaacacctc caaaaatcaa
    45601 aagacaagct catatcacga agggcgaaaa accgcggtac caccttcatt caatgaactt
    45661 gtcattctct tgttcttatg caattgtatg attgagtagc atgacttcct agcttagatg
    45721 gctcgcagca ccgccatttc tctggactaa gacaagtgaa aatcaattct caactttctt
    45781 attatatcgt ttttttaatc ttgcgtcaac tggaaatgat ctccgttgaa ttagaccaat
    45841 tccctacatc tctgattact ttttcaggat atattttttc ttactgccgt ttttcttttt
    45901 atcccaaatt ttcatattac taaacacagc tactagaata tttccaaata taaaggtgcc
    45961 tatcacccaa tatatggact cagttgttag gtattgtcga tccaagccat cctttaaatg
    46021 gaatagtata gcagtttggt taacaatcat aaaggttggc cagaaacttt tgttgaaaaa
    46081 agtagacatt ttcattattt gttgccgctt tctgtaaggt taatactcaa taaaaatcaa
    46141 aaagcaaact aggaagctag cctcaagctg tacttgagta cggcaaggca acgctgacgt
    46201 ggtttgaaga gtataggctt agtatactac taggcaagca aataagcaaa taaacaacta
    46261 gaatagaaaa agatagggct ctaaaaactg acttctattc cttaaaaacg aaccagcttg
    46321 actgattcgt cttcttacat ttatctccta cttccgatac attttaaact gtaggaagag
    46381 gtcgctatat ttccctgtcc atttatggtc aaatttctca taaacttcta ggtgtttcat
    46441 ggtttcaaca tcgggataga aggccttatc ttcctttgtt tcctctggga gcaattcctt
    46501 cgctggtagg tttggtgttg aatagccgac atactccgca ttttggagag cattttcagg
    46561 tttcaacata aagttgataa aggcataggc tgagttttgg tttttaactg ttttgggaat
    46621 gaccatattg tcaaaccaaa gattgctggc ctctgtcggt accacataac gtagattttc
    46681 atttttttct aacatttggc tggcttcacc agagaaggtc acgccgattg caacattatt
    46741 ctgaatcata tagcccttca tctcgtccgc aacgatagcc ttgatatttg gagtcagttt
    46801 gtagagctta tccactgtct cttccaactg ctgcagatcc ttggagttga ggctgtagcc
    46861 gagggaattg agtcctagtc ccagcacctc acgcgcccca tcaaagagca tgatagaatt
    46921 cttatactcc ggcttccaaa ggtcatccca atgctcaggc gcttcatcta ccatggtttc
    46981 gttgtagaca attcctaagg ttccccagaa gtaagggatg gagaatttat tacctgggtc
    47041 aaaggactgg ttgagaaact ctggtccgat attttcgatt ccttcaattt ttgaataatc
    47101 aagcggaacc aagaggtctt cgtccttcat cttgttaatc atgtattcac ttggaatggc
    47161 aatatcgtag gtcgttccac cctgctttat cttagtgtac atggcttcgt tggagtcaaa
    47221 agtctcgtac tgaacttgaa ttcctgtttc ttctgtaaac tgagtcaaga gttcaggatc
    47281 gatatagtct ccccagttat agataaccaa tttttgacta tctcgactat tgattttact
    47341 atctaaatga gtcgcaattc cccacaagac aaggataatc gctgcaattc ctgctaaaaa
    47401 tgaatagatt tttttcatgc ttgctcctcc ttctcacgag agataaagta ataacctaca
    47461 actaggataa tactaaagag aaagactaga gcagacaggg cattgatttc taaggaaatc
    47521 cccttgcgag cacgagagta aatctcgact gatagggttg aaaagccatt tcctgttaca
    47581 aagaaggtca cggcaaagtc atctaacgaa taggtgaagg ccatgaaata accagtaatg
    47641 atagacggag tcaggtaagg aagcatgatt tccttgaaca tctgaaattg actagctccc
    47701 aagtcatagg ccgcatgaat catgtcgcca ttcatttcct tgagtcgagg caagaccatc
    47761 aagaccacga taggaatgga gaaggccacg tgactagata gaacggtcaa aaagccaagt
    47821 gaaaacttga gttgggtaaa gagaatcaag aagctagcac caatcataac gtcaggcgca
    47881 accatgagga tattattgag tgatagaaag gcttcttggt atttcttacg agactggtag
    47941 atgtaaatgg caccaaaagt cccgataatg gtcgctatca aggctgatag gaaggccaag
    48001 aaaaatgtct gagccaaaat cagcatgagt ctcccatctc caaacatggt ttcaaagtga
    48061 gtccagctaa aacctgtaaa gctattcata tcatcaccag cattaaaggc atagccaatc
    48121 aagtaaaaaa tcggcaggta gaggaccaga aagaccagtc ccagataaag gttggcaaat
    48181 tttttcatcg ttctctcctt tccttagtca cccacatggt gatgaacatg gtcaggatga
    48241 gaatcacacc gatagttgaa cccataccat agttgtcatt ggttagaaaa ttctgctcaa
    48301 tagccgtccc caaggtgata acgcggttcc caccaatcaa acgggtcagc atgaagagac
    48361 tcaaacttgg gataaagacc gactgaaccc cacttcgcac accgttcata gatagaggga
    48421 agatgacatg acggaaggtc tcccacttag ttgcaccaag gtcgtaacta gcattgatga
    48481 gattattatc catttcgtct aagacattga aaatcggcaa aatcataaag gggagctcga
    48541 tgtagcttgc gacaaagata aatgagaaat cagtaaatag caactgctgt gaaccaattc
    48601 cgataaattc caagaattgg ttaatagagc cattctgacc aaaaatcccg ataaaggcat
    48661 aagccttaag aagaaggttg atccaagttg gcagaataat cagcataatc cagagttgac
    48721 ggtgtttgag acgggtcaaa aagagggccg tcggataact gataagcagt gtcacaaagg
    48781 tcacaatgcc tgcataaagc actgagttga aactcatttt aagataggtc aagttttgtg
    48841 acgcaaagta agatttgtaa ttttctaaac tgaactggcc ttcgatgttg aaaaaggatt
    48901 gaccgaaaat caagaccaag ggtgccaata caaagagcgc aatccaaagc atgtagggta
    48961 ctacaaagag tttagagctt gttttcttca tctctttcct cctcgattgc attgatcaaa
    49021 cctgcttctt gctcttcgat ttccacgtat tcttcgatac gagcatcgaa ctcttcttcg
    49081 gtttcattga gacgcatgat gtggatgtct tctgattcaa agtccagacc gatttcctca
    49141 cccacgatgg ccttacgggt tgagtggatc atccattcat ttccaagttc gtcataggcg
    49201 ataatttcat aatgaactcc acggaagagc tgggtgtcga ccttaacttg gagcttgcct
    49261 tcttcaggaa gggtaatgcg caagtcctct ggacgaataa cgacctcaac aggttcattt
    49321 ggcttcatcc caccatcaac cgcttcaaag cgtttgccgt taaattcgac caagtagtcc
    49381 tcaatcatgg tacctggcaa gatgtttgac tccccgataa aggtggcaac aaagtggttg
    49441 attggctcat cgtagatgtc cacaggggtt ccagactgga caatctcgcc atcattcata
    49501 acgaaaatcc agtcactcat ggcaagagct tcttcctgat cgtgagtgac aaagacaaag
    49561 gtaatgccca atcgttgttg taattcacgc aattcgtact gcatgtctgt tctcaatttc
    49621 aagtccagcg ctgataaagg ctcgtccaac aagaccacac ggggttggtt gatgatagca
    49681 cgggcgatgg ccacacgctg acgttgtcct ccagaaagtt tgcggatgga acgtttttca
    49741 taaccttcca actgaaccat cttgagaact tccgctacac gctgctcgat ttctttctta
    49801 tcaattttac gcaagcgaag tggaaaggca acattttcaa acacattcat atgtgggaac
    49861 aaggcatagg attggaagac ggtatgtacg tcgcgcttgt tggttggaat atcattgata
    49921 cgaacaccgt ctagcatgat atctcctgtc gtcgcatcca gtaaacctgc aataatgttt
    49981 aggatagttg atttccccga accagatgca cctagaaggg tgtagaattt cccttcttcc
    50041 aactcaaagt tgatgtcttt gagaaccttg gtgttgctgt cttcaaaaac tttagagacg
    50101 tttttgaatt cgataattgg ttttttcaat tggcataaat tccttctttt tcatagatta
    50161 accgatcggg gctctgtcag gtccccacta cctcttgcag ggagtaaaac cacctgcata
    50221 catcttcgct accgataggc tttcatcccc tttccatgac atagcagcag cttttcaaat
    50281 acagcttcct acttgctttc acccaagatc cggacttctc tttcaagcgt aatacctgag
    50341 tgttccttga ctttttcgat aaccgattgg atcaagtcct cgtagtcttt ggccgttcca
    50401 tctgcgacat tgatcataaa tcctgcatgc ttttctgaca cttctacgcc accgatacga
    50461 tagcctttca agccagcttc tgaaattaac tgacctgcaa aatgcccgac tggacgctta
    50521 aagaccgagc cacaagatgg gtattccaaa ggttgcttga gttcacgtag gtgcgtcaag
    50581 cggtccattt cctgcttgat aacctgatgg gttcctgggg ctagggcaaa tttaactgac
    50641 aagacaactg caccagactc ctgaatagct gaatggcggt aaccaaaagc caagtcttta
    50701 gcagacaggg tttcgatttc tccatccttg gtcaagacct tacaagactg caagatgtga
    50761 gcaatctcgc caccataggc acccgcattc ataaagacag caccgccaac gcttcctgga
    50821 ataccacaag caaactcaaa gccagtcaaa ctatgacgga gggcaatgcg agttgtttca
    50881 atcaagttag ccccagcttc tgcttcaatg gtatagccat caacagaaac gttattgagc
    50941 ttgtcacaca agatgacaaa tccacgaatc ccaccatcac gaacgatgat attgcttgca
    51001 ttgccaagaa ccatccaagg gatattttct tggttggcaa atttcacaag gcgcgccaac
    51061 tcaaaacgat ttcgtggaaa gaccaaataa tcagcctctc cacctacttt tgtataacta
    51121 tagctatgca agggttcctt aaaacggata tcaattcctt ctaagatttc aagcattttt
    51181 tctcttacag acatgtcact cttcctttta caaaattcat tccattatac catttttaga
    51241 gacatttgac gaccataaaa ataccttgtt tggattttgc ataagaaaaa gagtttcccc
    51301 cctttttatg attttttaca aaagatttcc ttggttccat aggcgaccag aacgagctcc
    51361 agtgctagaa tcacttcaac caagactgga tttgtcaacc agcctacttg gaaaagagat
    51421 ggtgccagat caaagaaggc atgcaagcca taggctgcta ggagataaat ccatttcttc
    51481 tggcgaacag cttggtaaac ccaaactgtc aaaagtaatt ggaaaccaag cgccaagatt
    51541 cgctcaaaac caagcaaata aatctgccag accgaaagtg actgaatggt ttttaacata
    51601 ttttcagaca gtaattgcat aacctgtgga ttctgagttt gaactgccga aagaacgatg
    51661 taaagattga gtaaactaat aaggcctaga aaaatcaact ccaagccacc atgccctagg
    51721 ccataggcca aggcatctgc cttttccaaa cttctctttt tctccaacca tttgaagaaa
    51781 acaagacgag ccgtttcctc aaaaaatgct gccatggcta ggccatagat aatatagata
    51841 agcggatgat cttgcaagag ggcaatacta gcgtcttttt gagggtgcaa aatcaagata
    51901 tgcaccagtt tttccaaaat ctgcgaagag acaaagaaag cgactgcacc caagcccaag
    51961 acagctagat taatctggta tttctttttg gcaaaccaaa tgcttcctat cagaaaagct
    52021 agcaacagca acatggtaat aatgatatga atggtcattt tcttctccta ttctgccttt
    52081 tcaatatctt ttttcatctc gtcaacattg aacttagcaa acaagtattg acggtcttgg
    52141 actgggaaac gttggtccaa ctggtcaact gctcccacct cgataatgcc ttccttgatg
    52201 acaaaatcca tgacatgtcc accgaaggtc aaatcatctg atatgaagtg cagatggtag
    52261 cctgccacac tgaccccatg gaaaatctca ggcgtccaga aaccaacaat agtccccgca
    52321 acattgtcac gactatattc cggttgatgg gttgcgacat cagcaaactt ggtatcgggt
    52381 gttgacttag gaatcatacg cacatgcata tgtaaaaatt ccccccgaat cttgatagag
    52441 cggaaaagat tttccccatc ataataagac tcaattcgtt ctttcaattc cttgtctgtc
    52501 atctcaaagc gctggcggaa aatgacctct gcctgatgcg gtaccactgc agcgtaagga
    52561 ataagggcat ctggtgacac ttccacaatt tctggctggt ctcctgaccc tttggcctga
    52621 taagccttgc catccaagac aatcaattcc ccatcaatgg aatccaaggt tcccaaacca
    52681 aggtcaccat gttctagcaa ttctcctact gtcatagtac caccataaag gccagccatc
    52741 aaggctccaa gagtattgta ttgaaataat ttcactggtt cctgcacgtt cttatccatt
    52801 cactttcttg tctgttattc tataaatctt actcctaagt ataccacatt tgcccctaga
    52861 tgtgaacgag agaaacgctc tagacattgc caagaaggaa aaaaaagggt acaatgtaac
    52921 aaaatcaagg gaggtctgga atgaagaaac aaagcaagta caaagaggtc gtttcctatc
    52981 tgaaaaatgg tatcgagtct ggacgatttc cgacgggtag tcgcctgcct tctatccgtc
    53041 aactgagcct tgactttcac tgcagcaagg acaccattca acgagccctg ctggaattac
    53101 ggcacgaaca atacctctat gccaagcctc agagtggcta ctatgtatta gaacaagggc
    53161 aacatcaaga cctagaaatc gaggttaccg acgaacatgc cagtgcctat gacgatttcc
    53221 gactctgtgt caatgaaacc ttgattggcc gagaaaacta cctcttcaac tactatgaca
    53281 atcaagaagg attagaagac ctaagacagt ccattcacaa actcctcttt gagcaagctc
    53341 tctactgcaa ggctaaccaa ctagtactga cttctggaac ccaacaagcc ttgtttatcc
    53401 tctctcaaat atcctttcct agacaagcca aggaaatctt ggtggaacag ccaacctacc
    53461 atcgaatgaa tcgcctcttg attgcacagg ggctggacta tcaaacgatt gaacgaggca
    53521 ttgatgggat tgacttggag gagctggaag gccacttcaa aacaggaaaa attaagtttt
    53581 tctacaccat tcctagattt cactatcctc tgggacattc ctattctgag caggacaaac
    53641 gatctattct taacttagct gccaagtatg atgtctatat cgtagaggac gattatctgg
    53701 gtgatttgga ctccaagaag ggccaaacct tccactatct tgatacagag gagcgtgtca
    53761 tttatatcaa gtccttctcg accagccttt ttcctgccct tcgtattaca gcactcattc
    53821 ttccaaatgc tatcaaagaa gcatttgtgg cctacaaaaa tatcctagac tacgacagca
    53881 acctcattat gcaaaaggcc ctgtcactct atattgacag tcaattgttt gaaaaaaatc
    53941 gtttggctcg cttgaccaat catgaatctt accaaaaaca aatcgaggaa aggataacta
    54001 aaacaccttg tctccttcct cattatcccc tacacgatgg tttattgcta gacctgagac
    54061 agtatcctaa aatcgccagt ctcaaacaca gtcaaccggg cttggacttc tttgaagagg
    54121 cctatttaag tacctgtcct tatcaatttg ccaaggtgtc cctagacaat ctggaaaatg
    54181 ttttaaacta tttaaaagca gaattggaat gacatccaac tctgcttttt cttattcttc
    54241 aacttcagtt agacttgctg ctttttcaag atagctttgg taagttcctt catccttaag
    54301 tttttggatg accttgtcta ccacttcttt caaatcatca ctattttttc taagagcaac
    54361 ggcattggcg tcgccgtcct tcatcttcaa gctgacagtt gcgacagcta agccagcgtt
    54421 tttagcagca taactaagtg caacaggctc atccatatga acagcatcta tttttccagt
    54481 ctgcaattca ttgactgctt cacccatatt agttagggaa gttaattgaa cttttggcaa
    54541 ttgttccttg accattgatt ctggaacagt ccctttttgg gctgcaatat tagcactttc
    54601 taggctagtt aaatccttgt atttttccac atcagcctta cgaaccaaga aactaatctt
    54661 gttttcatag tatgggattg aaaaatcaaa gacttctttt ctctcgtcag tagcactaat
    54721 tcctgcaact gctaggtcag ccttaccagt ttgaagactg gtcaaaacat tgtcaaaact
    54781 catgcttgag atttccaact taaccccaag ttcatcagcg atagcctgag ccatgtcgat
    54841 gtctgcaccg actacctggt tctttccatc aaccaatgat tgaaattcaa agggtgcata
    54901 gtcaggactg gttgccacaa ctaatttccc tttttgtttg atagcatcca cagcagactg
    54961 agaaccatta gaacctgact gacaagctac taagaagaaa cttgcaagaa aattacataa
    55021 aacaaatatc catttttttg atttcataaa taaacaacct ctctgttaat tttgtataat
    55081 tataacgata tccaagttac ttgtcaagtg ttttttaaat ttttatctca aaaatatttt
    55141 ttcgttcaaa aaaaggagcc atcagttgat ttcaagctcc tttttataca gaattaaact
    55201 attttatagt tcgacaatct tacctgtttc aaagtagaca acccattcac agatattttt
    55261 agcatagtca ccgatacgct ccaagtagga aataacttgg aaataatcac gacccgtaac
    55321 aatggcttct ggatttttct taatctcttc agtcgcaagg tcacggatag tttcaaaata
    55381 gtggttaatt tgctcatcca tggaggccac ccggtatgcg tcgtcaacag aaccattaag
    55441 ataaagatca agtgctgctt caacaacgct tttaacttca cgtcccattt ttttaatttc
    55501 ttcctctaca gctggaatgc gctcttcccc cttcatacgg atggttgcct gggcaatggc
    55561 tacagcgtga tcccccatac gctccacatc tgatacagcc ttaaggacag tcaagactgt
    55621 acgcaaatct tgagagactg gttgttggag tgcgatcatt tcaaatgatt tcttttccag
    55681 tttcacttcg tattcattta cttctgcatc atcttcgatg acctcttttg ccaggtcacg
    55741 gtcatgcgtg acaaaagcac gtaccgtacg attgatttgt gagagcactt cttgtcccat
    55801 agcgtagaac tggttatgta atttctctaa atcttcttca aattgagatc gtaacatctt
    55861 tcatctcctt atccaaattt tcctgtaata tagtcttccg tttccttgtg ttggggatca
    55921 aggaacatct gcttggtatc attaaattca atcaaatctc catctaggaa aaatcctgtc
    55981 ttatcagaga tacgtgaagc ttgctgcatg gaacgggtta ccagaagcat ggtgtacttg
    56041 tcttttagac catacaaggt ttcctcaatt ttaccagctg aaatcggatc caaagccgaa
    56101 gttggctcat ccaagaggat gattttagga ctagttgcca agacacgggc cacgcagaca
    56161 cgctgctgtt gaccacctga caatccaata gctgaatcat atagacgatc cttgacctca
    56221 tcccagatag aggcaccttg caaggctttt tctacggctt catccagaac ctgcttatcc
    56281 ttaattccat tgatacgaag cccgtagaca acattctcat agatagtcat agggaaagga
    56341 ttaggttgtt ggaaaaccat tccgatttcc ttacgtaatt caaccgtatc tgtacgcgga
    56401 ctgtagatgt tgtgaccatt gtacaccacg gatccagttg tggtcacctc tggattgaga
    56461 tctcccatgc ggttgagaga cttgaggagg gttgacttcc ctgatccaga tggaccaatc
    56521 aaggctgtaa tttccttagg ttggaaagat agggaaacac tattcaaagc cttcttttta
    56581 ttataataaa cggacaggtc tgatacctgt aaaatcgcat ctgtcatacg gtttcctttc
    56641 taaccaaagt gaccagatac atagtcattg gtggactgta gcttggcatt ttggaaaata
    56701 gttgcagtct tgtcatactc aatcaaatca cccaagtaaa agaagcctgt atagtcactt
    56761 gcacgagcag cctgctgcat attatgcgtt acaatgatga tggtaaagtt tttcttgagc
    56821 tcaaacatgg tctcttctag ttgcatggtc gcaatcggat ccaaggctga ggctggctca
    56881 tccattaaga ggatatctgg cttaacagag atggcacgag cgatacagag acgttgttgc
    56941 tgaccacctg ataaggtcaa ggctgacttg tggagatcgt ctttaacctg atcccagagg
    57001 gcagcctgac gaagggaggt ttctacgatt tcatctagga cttgcttatc cttaactcca
    57061 gcacgttcat gcgcaaaggt aatattacgg taaattgact tagcaaatgg attggggcgt
    57121 tgaaaaacca ttccaatgtg tttacgcatt tcataaacgt tgatttctgg acggttgaca
    57181 tcaattccac gatagagaat ctgcccagtt actttagcaa tatcaatagt atcattcatg
    57241 cgattgagac tgcgtaagta ggtagatttc cccgatcccg acgggccaat caaagctgta
    57301 attttatttc tttcaaattg catatcaatc cccttaatgg attcattttt accatagtaa
    57361 acatggacat ccttagtaga aagggctact ttttcttcag gaaaggtaag gatatgcttc
    57421 tcatcccagt tatatgttga catggcttct cctttaggca gcggttaatt tcttgtgtag
    57481 atagcttccg aacttacgag ctccaaagtt aaaaatcagg ataaagatca ggagcacagc
    57541 ggcagaacct gctgatacaa tggttccatc tggaatagtg ccttcactat tgactttcca
    57601 gatatggaca gccaaggttt ctgcttgacg gaagatagag atggggctag tcacactgag
    57661 gatattccag ttagaccagt caagagctgg cgccgattgc cctgctgtat agatcagagc
    57721 tgcagcttcg ccaaagatac gaccagatgc caagacgaca cccgttacaa tacctggaag
    57781 cgcttctgga ataacaacat gaaccactgt ctcccagcga gaaatcccaa gagccagacc
    57841 agcctcacgt tgggtatggt gaacgtgttt caaactatcc tctacattac gcgtcatctg
    57901 aggcaagtta aagactgtca aggccaaggc acctgaaatg attgaaaatc catactcaaa
    57961 ctggactaca aagatcaagt aaccaaagag acccaccacc actgatggta aagaggacaa
    58021 gatttcaata caagtccgca caaagttggt aacaggacct tttttagcat attcagccaa
    58081 gtaaatccca gctcccatag aaagaggtac agaaataatc aaggtaatga ccaataggaa
    58141 aaaggaattg taaagctgaa tgccaatccc accacctgct tgaaaagcag aagaccttcc
    58201 agtcaagaaa gaccaagaga tatggggcaa gccccgaacc aagatataga gaatcaagga
    58261 agccaagatt gtcacaatga tgctagcaat cgtatagagg acagctgttg caagtttatc
    58321 taatttctta gcgcgcataa tttttctttc ctctttcttt cgtaatcaat ttaatcacac
    58381 tgttaaaaac taagctcatc aagagcagta ccaaggccag tgaccagaga acattattat
    58441 ttacagttcc catgacagtg ttcccaattc ccatagttaa tatagaagtt aaagttgcag
    58501 ctggtgtggt caaggaagtt gggataacag ctgagtttcc gacaaccatc tggatagcta
    58561 gagcctcacc aaaggcacgc gccatcccaa agaccactgc agtgaaaata ccagaacggg
    58621 ccgccttcaa gatcacacgc cagatagtct gccagcgagt ggctcccata gcgaaactgg
    58681 cttcacgata ataacgagga accgcacgca agctatccgt tgtcataaag gttacggtcg
    58741 gcaaaatcat gacaaagagg acggaaatcc ctgacaaaat cccaaaacca gtcccaccaa
    58801 agacactgcg aacaaaggga acgacgactt gcaagccaat aaatccgtac actactgaag
    58861 gaatcccaac caggagttca atagctggtt gcaaaatctt cgcccctttt ggtgatactt
    58921 cggtcataaa aactgctgca ccaatagcaa agggtgttgc gataagggct gagagaatgg
    58981 taacgataaa ggaacccaaa atcataggaa gggcaccaaa ttctttacta gaaggattcc
    59041 aagttcctcc caaaagaaag tcaaagatat tcacaccatt gacaaagaag gtcgacaagc
    59101 ctttttgcgc tacgaaaacc aaaatcatgg ccacaaggat gactatcaaa gaaagacagg
    59161 caaaggtcaa accttttcct aatttctcca gacgagaatt ctttgatgga agcaacattt
    59221 tcttagctaa ttcttcttga ttcattattg tctcccttcc aacactgtca cagttccggc
    59281 agcatctttt tcaaccttca tttccttaat cggaatatac ttcaatcctt tgacaatccc
    59341 ttcttgggtc tcatccgaga gaacaaaatt gagaaattct gcagctaact cattgggctg
    59401 ccccaatgta tacatatgct cataagacca caagggccaa ttattactac ttatattttc
    59461 tggacttaag tcatagccat tcaacttcat gcttttgacc gaatcatcta tataggtaag
    59521 agataaataa gagatagctc ctggactttt tgatacgatt gattttaccg ctccatttga
    59581 atcctgctcc tgactttgca tggcagactg accttccata atgacagtat caaaggtagc
    59641 acgagagcca gagccggctg cccgattgat aacagagatg ggtaagtcct taccaccaac
    59701 ctctttccaa ttggttacct cacctatgaa gatttgacga agttgctctg tcgttaggtt
    59761 atcaacatca acctccttat tgacaatcag agccaagcca gctaccgcga ccttgtggtc
    59821 aacaagagca gaagcatcaa ttccgtcttt ttcctcagca aatacatctg agtttcctat
    59881 atcaactgcc ccagactgaa cctgggacaa gcctgtacca gaacctcccc cttggacatt
    59941 gaccgttttt ccaacatgga tcgtgccaaa ttcatctgcc gctacttcaa ccaagggttg
    60001 caaggcagtt gagccaacag ccgttatgga ttctccacga tcaatccagc tagcacagcc
    60061 tactaaacaa gccgtcagcc aaaaagcgat aagagacaga gcaagctttt ttcttttttt
    60121 cactgttttt ctcctcgaaa ataattatga atactgtgaa ttttttaagt agttctttat
    60181 gagttgacgc atgaattctt accaaatttc tgcgcaattg attatttata taatataggc
    60241 tatattactc tttcctaacc tccttttttc atatgtggat aaaatctctt gtctatccct
    60301 tcccccattg tcacccatta tagtcatttc gtgtctcttt ttcccctttt taatgcaagg
    60361 gaaattactc ttcttagatg ataatccaaa agctagaaag gtatctcaaa cctctctact
    60421 ctcccagact agtttacaac taaaagaaaa agattctatt ttatgagaaa tctagtttac
    60481 aagcggtaag aacgctaata actaaacttc ttgtactctt tgaaaatctc ttcaaaccaa
    60541 tgttttgagc tatctatggc tagcttccta gtttgctctt tgattttcat tgagtagtaa
    60601 aactacatgt aatggcaatc aagatatcaa gaatcatcct actaaaaaaa tccatacttt
    60661 cactataaca tagaataaga tatttgacta gcattttcat ttgaatctga ggccttttgg
    60721 aaaataattt ttcaaaacat ttccagtaac ctttgcaaag cccaagccat tgcctttaac
    60781 caaaacttgg taccaaccat ttggcagact ttctgccagc tgaacggttt ctccagccgc
    60841 atacttgaca aacgcttctt ggccaatttc aaccgactgt tcgacctgac tcggtttcaa
    60901 ggctaaacca agagcgaaac tgggctcaaa gcgtttcttc ttaaaagtac ccagatgcag
    60961 tccattgcga gcaatcttga gcttccctaa atctggcaaa agttctggca agagataaag
    61021 ctggtctcca aaaatctgca agatacccgg tagattgacc ttcaaatggt tttgggcaaa
    61081 ttcctgccac aaggcaactt gttcacggct gaggttactc ttacttgcct taaatttagg
    61141 agctggattg ttacccttaa actgtagatg ggcaacaaac tgaccctctc ccttaaactg
    61201 atgagggtac atccgagccg tttctggcag gtcaatacca gctaccattc cattgatatg
    61261 ctctactggc aacaagtcaa aatcatactc ttccagcaac caattgacaa tctcttcgtt
    61321 ttcctcgggt gcccaggtac aggtcgaata aaccagacga ccaccttcag ctaacatggt
    61381 cactgcatcc tccagaattt ctctttgcaa gctagcacat tgactcggat aatctaagct
    61441 ccaatagtcc atagcatcag gttgcttacg aaacattcct tcaccagagc aaggggcatc
    61501 aagaacgatt aagtcaaaat agcctttaaa gaccttgacc aagcggtcgg cagattcatt
    61561 ggtcaccacg acatttgtcg ctccaaaacg ctccatgttt tcaaccaaaa tcttagcccg
    61621 tttgcttgaa atttcattgg aaacaagtag cccctcccct gctagatagg ctgccagttg
    61681 agttgatttg ccccccggtg cagcagccaa gtccaagacc ttcataccag gactgggttg
    61741 ggctacttga gccaccattt gagcagcagg ttcttgcgaa taaactaaac ctgtagcatg
    61801 ctcaggcgat ttccctgaaa ccttcccata gtggccccaa ggggtttgag taatggcatc
    61861 agaaaaggaa agttgctctt cttttaaggg attgacccga aaggccgaaa ccgcttcctc
    61921 ctcaaaagag gcaagaaaat ctcttgcctc atctcctagt atctctttat atttttcaac
    61981 aaatccttct ggaaatttca tttaagttct tttcctttcg taaatatagg actgaatttc
    62041 ctcctgcatc tcaagaggca ccatcatgac cggctgtctg gtttgaaaat caggagcttc
    62101 accaaaaagg gtcacaaccc gatagcccag actttcccct aaaatactag ctgcggcata
    62161 atcccatggt tgcagataag tgagataggt caacaaacgc cctgacaaaa tcttggcaaa
    62221 actaatggcc gcacttccat agacacgaac accaagaacc gatcggctca aatcagccag
    62281 cccccattca ttggtttcca gcataccact attccctgca atgagaaaat ctccaagtgg
    62341 tttagtttta aaaggagcta ggggcctatc atttagacaa actggaaatt ccccaccacc
    62401 gtggtaacaa tcccctttga ccacatcata aatcagacca aactgtccct gaccattttc
    62461 aaaataagcc atcataacag caaaatcttc ctgctgggct acaaaattat tggtaccatc
    62521 aatgggatca atgacccaaa ccttgccctc ttgaaccgag gctcgcagac aaccttcttc
    62581 agcacaaatc ttatcctcag gataacggga caaaatctca ccaaccaaga gttcctgaac
    62641 ttctttgtcc agtctggtca ccaaatctgt tggagaggac ttggtttcaa cacgcaagtc
    62701 ttcctgcata tggtcaagaa tgtactgacc tgctttctta acaagctctt tagcaaattc
    62761 aaatttactt tccaagagaa atctttcctt cccctttttc tttggcagcc tgaactgctc
    62821 ggtaaagtga atagccacta accgtttcaa attctcgtcc caaacgtttc tcttcgctct
    62881 tgcttggcac gaccgctttg aatcccttat aggagtccag taacttttta gcctctactt
    62941 tgccttcata ggcagcttca acatcattaa aaaaagaaag cactgaagca agttcttcag
    63001 tgctccacga caaatctagt gggtaactat actgtttgtt cattaactaa taccagctct
    63061 cattcttgct tcttttagtt cttgcttacg ataactacga gggagaaaag cacgaatctc
    63121 atcttcatta aaaccgattt gcatacgctt ggcatcaata ataattggac gacgcaaaag
    63181 actaggatac tgctcaatca aatgaagcaa ttccgatacc gaaatactct ctacatcaat
    63241 attcaatttt tgaaaaattt ttgaacgagt tgaaatgatg tcatcagtac cattttcggt
    63301 caaggaaagg atgtgttgca attcttttct tgttaaagga ctggtcataa tattgtgttc
    63361 cacaaaggga accttatgtt tttctaacca ggccttagcc ttacgacatg atgtacagct
    63421 cggtgataga aatagtgtaa tcatgctttt ctcttcttat ctatactttg ctacttctat
    63481 tatacaaaaa aataaggcgc ttgactaggg atttttagaa aaaaagccta ttttttcagg
    63541 aaaaataggc tgtttgcgaa cgattgacac aattggattt ggttaattca ctcttaacga
    63601 tggttttaaa cgatatatat atttatatat gtaaattaaa aacatctttc ctttcacttc
    63661 ctacgacttt tcagacacag atagccaaag aagttttcat agagggcaaa aaagaggagg
    63721 aaggcatgaa gaaagaaggt ctctggcaaa atcataataa caggatcctt ggctggatca
    63781 aaaagccagg tatcatctcc cacaaagaga atttgatgga aaagagtaaa gaattggtca
    63841 aaaccaatca aaactccccc aagtccaatc attacaggta aaactactag agccaggaga
    63901 ctttttcgat aaagagacaa aaagtccttt ttcacaatcc tattgacaaa gacatagaaa
    63961 cttggcagtg tcactagagc tactagctga accaaatgaa agagattctt gaccactgcg
    64021 aaatggtgca gaccagctgc tgacgaacga aaatcaggca tctgtaagac ctgactaaaa
    64081 ggattggtca gataattcat caagatatga aaattgtatt gaatggtttc tggttttaga
    64141 tagactcgat tcgttaagtt tagccactga atctccatag gatagaaaat ccaagccaga
    64201 taaatggtca gaaggatgga gagggagagg agaaagagca tagagcccca aaagatcaat
    64261 ttagttttca tcaaaatccc actccgcaag gctagaaacc acatgtgtcg gtgcgattgg
    64321 caggccagct acttcttctg ccttagtaaa acctgtcgtc accaagagcg ttggaatgcc
    64381 attgtcaatc ccagcccgaa tatcagtcaa ataattgtcc ccaaccatga ttaactcttc
    64441 acgttccaaa cctaagtgct caaccgcctt gtccataatg atggcatttg gttttccgat
    64501 ataaaccggc ttcactcgtg tcgctacttc aagcagcgta atcagtgagc cagcacctgg
    64561 caaaagaccg cgttccgtcg ggatgttgag gtcaggattg gttccgataa aatgggcacc
    64621 cttttgaata gcaagagttg ctgtggcaaa tttttcatag tcgacttgcc aatccagacc
    64681 aactaccacg taggcaggtt tttccttgtc ttccacataa ccagccgcct tgatggcttc
    64741 cttgagtcct gcttctccga cgacatagac ggtcttttca agccccaaat cattcatata
    64801 gtcgatggtt gccaaagtcg ctgtgtagac agtcgatagg ggcgtatcga tattaaaatt
    64861 ctgagccaac atctccttaa cactctctgg agtgcgggtt gtattgttgg ttacaaagag
    64921 atagggaatg tcccgctttt gcaattcatg aacaaaagtc tctccagcag ggattcggtc
    64981 tttcccctta taaatggttc cgtctaaatc aattaaatag cctttatatt tcatctattt
    65041 ctccctaagc cttttttatt tcttgccaag taatgattgc ttgggcattg ataaccccat
    65101 cacttgtaat ttcatgcttg ctttccagtc cagtccgttc aacagccgat gtaatcaccc
    65161 cacctggtcg aacttccttg acatacttga ggttgatttt cttgggaata tagtgggtca
    65221 aaaaatccgc tcccatgacc tcaaaaatcc agtccaagta tttactgtta ttgacatgac
    65281 cattcatatc caagtcgtaa aaacgaacat ggtaatcctt gctgatcggt tcttccaagg
    65341 actcatactt cggtccacgg ataagttttt tatcaaaatc agactggtaa ggagccacaa
    65401 tctcaggttc aacaacatgg acttttcgac tgtcgcggtc catgagaaca aaggtcgcca
    65461 tcatgtggat gagctcctgc tccgcttcat tataaatagt aaagcgacgg tagcaaaaaa
    65521 gtcgattgta gctcaaggct tccgtttcga tggtaatttc ttccgcaaaa cgaggcaaac
    65581 gaaccacctc aatatcatat tctacgataa tccagaccag attatattct tccaaaatgg
    65641 ccttatcact aactcccagt tcaatcgact gcatccctga aacttgcagt gacagcaaaa
    65701 tcacatctgg aagtttgata tgaccgttca tatcagccat atcaaaagga attttcattt
    65761 tcatttgata agttaagccc atgatcctac tccaaaataa atcgttctgc tacagtatct
    65821 cccaaaaaga gacctctctt tgtcatgcga acgtggtcac cctcaatctg catgaggcct
    65881 tgttgaacca aatctctgac aatttctcca taaagtccag caaaagactg tccaaatttt
    65941 tcctcaaatc gcgccatgga aaccccggat ttcttgcgga gtcccaagaa catttcttct
    66001 tccatttgct ccttttgact caggtgatct tctgtaatac aagcattgcc ttcctcaacc
    66061 gcactgagat aatgacgaat gggaccatga tttttatagc gtactccatt gacataacca
    66121 gatgcccctg caccaatacc atagtattca gcattgtccc agtacatgag attatgacga
    66181 ctttcaaaac cgggtttgga gaaattagaa atctcataat gctcaaaacc cgctcgctcc
    66241 agctctgcaa tgatgtactc aaacatctcc gcttctagtt cctccttagg cagaggcaat
    66301 ttcccacgtc gcatccggtt cataaagacc gtatggtttt ctaaaatcaa actatacaaa
    66361 ctcatgtggg gaatatccaa tccaatggct ttagccacat tttcctttac ttgctccatg
    66421 gtctgaccag gcagagcata aatcaaatca atggagatat tgtcaaaacc agccagtttc
    66481 aggcgatcga tattttcata aatatccttc tccaaatgac tgcgcccaat ctttttcaac
    66541 atcttatcat caaaggtctg gacacctagc gaaacacgat tgacagccga atttttcaaa
    66601 acagctatct tatccgcatc caaatcgcct ggattggctt caatggtcaa ctcttctaag
    66661 acagacaagt ccaagttttt agtcaagcca ttcagtaaaa cctccagttg cggagccgac
    66721 agggctgtcg gtgttccacc accgatataa agggttgaca acttttcaat atcataagaa
    66781 cgaaactctt ccagcagatg ctctaaatag ctgtcgactg gctgattttt gatgaagacc
    66841 tttgaaaaat cacaataata acaaatctgg gtacaaaatg ggatgtgcac ataggctgac
    66901 gttggttttt tctgcatagt aattattata ccacaaagac tagattccag ataaaaatca
    66961 ccatccccag atacatagtc cgttcggaga tggtgatggt ttattcttct gttatatcaa
    67021 tcacaatctc ttctgagtca tcaagagctt cggctttttc ttgccattgt tccttgagat
    67081 tatttaattg attttttgat gcttctgtcg cttgaaaagc ataggattta gcttgagcaa
    67141 gtatactgtc cacagtgatt tcacctgact caacctgttc ttttgttttc agaacaaaat
    67201 ctgtagcctg ctccttaact tctgtcagtt tttcacagac ttgctccttg gcatactccg
    67261 gatcttctct caaatcatct agaaaatctt gagcctgact gcaaacttgt ttgcccttat
    67321 cacttgttaa aaacaaggca agagctgcac ctgaaacggt tcctaaaagg attgaggata
    67381 atttacccat aaggattctc cttttttatt ttttgaaaaa tttacttgca agacgaagag
    67441 ctgacagact tgcaccagtc ttgagtgttt ttgaaccagc tgatgaagct ttcttgctca
    67501 agacacgcgc atggtcattg aggtctgaaa cagatagaga taaatctgca acagcactga
    67561 agagtggatc aatcgtagcc accttgacat tgatatcatc tgccaagaca ttgaccttag
    67621 ccaacaactc attggtgtga tgcaaggtca catccacatc tgaagtcaag gttttaatcg
    67681 tcttttctgt ttcatcgatg acacgaccaa gcttttgtac agtaatgatc agatagacca
    67741 aaaagacaat caaagctagg gcaacaagaa tatatgcaac ttctaacatt tagttttcct
    67801 cctctgtaat atagtaaggg gccttctttc gattttgata aataacgatc attataccga
    67861 gaccgataag gacaactgac agccattggg acactcgaaa gccgaagaac atgagactat
    67921 ctgttcgcat accttcgata accatacgac cgaaaccata ccaaatcaag taaaaggccg
    67981 tgatatgacc tcgtctgaga ctcttccatt tccgtctaaa aatcagaatc aaggcaaagc
    68041 caagcagatt ccatagagac tcataaagga aagtcggttg acggtagctc ccctcaatat
    68101 acatctggtc acggataaag ccaggtagat aatccagatt atccactgtt gcaccataag
    68161 cttcttggtt aaagaaatta ccccaacgcc ccaaactttg agcaatcata acgctaggcg
    68221 ccgcaatatc tagaaaatcc caagtattga tgagtttacg gtcagcaaag atatagagca
    68281 caagagcccc agttatcaaa ccaccgtaaa tggccaaacc accattccaa atggcaaaaa
    68341 tctctcctaa attctgacta tagtaatcaa atcggaaaat aacatagtag agacgagctc
    68401 ctaaaatagc caagggaaag gctactaaga taaaatctaa aatatcgtct ggtatgatct
    68461 tctttctagg tgcttctttc atggtcaaat aaaccgcaag aatcaagcct gtcacaatac
    68521 ataaggcata ccaacgaatg gctaggggtc ctagttgaat agcaattgga tcaagcattt
    68581 tgcacctcat ttcgagcgat tagacttgtc agtcgttcgt cgaacaaacg ggtcgcatca
    68641 aagcccattt ccttggcacg ataattcatg gcagctgcct caatcacaac agagatatta
    68701 cgacctgttt taactggaat acgaatacga ggaatggcta cgccagaaac ttcaagttcc
    68761 tctgcattat ttccaagacg atcaaaggtc ttatgcgtat cgtaattttc caaatagaca
    68821 gcaagctgaa cctgtgaaga atccttgaca gcactcgcac cgtagagact cataacatcg
    68881 ataataccaa ccccacgaat ttcaatcaag tgtttcaaaa tttcagctgg ttcaccccag
    68941 agagtaatct catccttggc aaagatatcg acacggtcat cggctaccaa acggtgacca
    69001 cgtttgacaa gctcaagacc tgtctcgctc ttaccaattc cactatctcc ctgaatcaag
    69061 acgcccatcc cataaatatc catcaagaca ccgtgcacac tggtacgttc tgccaaacga
    69121 gaatccagat agctagataa ctctccagat aaacgactgg tagctgcacg gctggttaaa
    69181 atagcaatct tacattctct agcagccttt aacatctcct ctggaaccac caaaccacgg
    69241 gcaacaatga ctgctggtgt ctcaggtaga aacatttttt tcaaaacttc ataacggctg
    69301 ttggaaggca tgctgatcag ataagaccac tccttcatcc ccaaaagttg aatccgctct
    69361 ggtgtatagt agtcaaaata gcctgtcatt tcaagaccag gtcgcgtaat atccgctgta
    69421 ttgatttcct tttcaagcaa ttctggttca ccatagacaa tgtctagtct aagcttttca
    69481 atcacttctt ttactaaaac cgacatcatt tcctccttca aatgagttct tctctctatt
    69541 atatcaaatt gtaggaggaa gtttcagatt tttgcaggct ttggagtatt tatttaaaag
    69601 aaaaaggact agatttctct agcctttcat ttcaattaga attttttacg tttacgagct
    69661 acttctgatt tacgtttacg ttttacagaa ggtttttcat agaattcacg tttgcgtgtt
    69721 tcttgaagag taccagcttt agtaaccgca cgtttgaaac ggcgaagtgc gtcgtcaaga
    69781 gattcattct tacgtactac tgttttagac atttttttca ctcccttcaa gttcaagatc
    69841 tattctattt tacacgtaaa aggaataatt gtcaagagga aactaagttt tttattcttc
    69901 ataatgatta ataatatagt tcaccatctc ctccatatct gcttcagata aaggtaattc
    69961 ccagtttgtt gtttccattt taagaaaagc atcactgact ttagttattg tatagcaatc
    70021 tttaaaaatt ggaatttttt tagattgttc aaataagatg cctattctat catataagac
    70081 gtgaagttct ttactatttg gatcaatatc aaaagactgt aaagagatta agatgtcatt
    70141 tcctttatat gacaaatcaa tccacatgtg atttgataaa tcatatggcc tagataatct
    70201 actacccgag gtgtactttt tatttcctcc gcctcctgaa tattgatttc ttgtggtata
    70261 tggtttatct tttgacttag taaaaagaaa attcccctcc ttatctttct tttttgtaat
    70321 gaagcctatt atactttttc tttcttccgt tctagcactc ttatatgctt cttttatttt
    70381 taaaaattct tctttattca tgtgtcctcc taaagttaag ttgaagtttt atatgtctaa
    70441 aaccactcac tccaaagagc aagcggttct tatacttttt atttttcgag taagctaagc
    70501 gcttcagcat ctgcgatgat ggttacatca gggtgatttt ggaggctact tgcaggtagg
    70561 ttctcagtca ctgggccaga tactgttccg gcaatggctt ctgctttcga ctcaccgtaa
    70621 gcaaaaagaa taatagactt ggcatccaaa atgtttttaa tccccattga aatagcttgg
    70681 gttgggacgt cttcaatctt ggcaaagaag cgtgcattgg cttcgatagt agactggtca
    70741 agttctacta catgcgtttg actgtcaaat ggagtaccag gctcattaaa gccgatatgc
    70801 ccattgcgac cgattcccaa gatttggagg tcaactggat ggtcagccaa aatttggttg
    70861 tagcgttcaa cttcagcttc agcattgtcc ttaacaccac gaggcaagaa actttcttta
    70921 aatggttttt ggttgaacaa gttttcttgc atgaagtaac gataagactg tggattgtcc
    70981 ccatcaaggc ccacatactc atcaaggttg acactggtta gatttgaaaa atcaaggtca
    71041 ctctcaacaa tttccttgta aaattcaagt gggctacttc ctgtcgcaag tcctagagtt
    71101 tgagctccat tagccaattt ttccttcaaa atctcaaaag caacttttcc accttgaact
    71161 tggttttcaa ctttaataac tttcatcttt tcatcctcca tttctgtcta tatttattat
    71221 atggtataga ccaatttttg tcaagtgaaa acgatttaat ttctaaaaaa agagcgtcca
    71281 aacttgaaac gtgttataat ggataggatt agaacttaga aagaatgaac aaatatatga
    71341 atacagctga ttttgatttc cacttgccag aggaattgat tgcccaaacg ccccttgaaa
    71401 aacgtgatgc ctccaaactc ctcatcgtca accgtgagac aggagaaatg caagataaac
    71461 atttccactc tattattgat atgctggaac ctggtgatgc ccttgtcatg aacgacaccc
    71521 gagttctccc tgcccgcctc tatggtcaaa aagtggagac aggaggtcat gtggaacttc
    71581 tcctccttaa gaacactagt ggagacgagt gggaagttct ggctaaacct gccaaacgcc
    71641 tcaaggtcgg tactcgtatc agctttggtg atggccgcct cagcgctgtc gttacagaag
    71701 aattgaccca cgggggacgc attgtccgct ttgaatacca aggaattttc ctagaagtct
    71761 tggaaagtct gggagaaatg cctctgccac cttatatcca cgaaaaatta gatgaccgtg
    71821 aacgttatca aaccgtctac gccaaggaaa gcggctctgc tgcagcaccg actgctggtc
    71881 ttcacttcac caaagaactg ctggcagaaa tccaagctaa gggtgttcat ctagtctatc
    71941 tgactctcca tgtcggactc ggaaccttta gacctgtttc tgtggataat ctggacgaac
    72001 acgaaatgca ctcagagttc tatcaacttt ctgaggaagc tgctgccacc cttcgctctg
    72061 tcaaagaaaa tggtggtcgc gtcatcgctg tcggaaccac ttctatccgc accttggaaa
    72121 ctattggttc caagtttgat gggcaaatcc aagcagattc tggttggacc aatatcttta
    72181 tcaaacctgg gtatgagtgg aaggtcgtgg atgccttctc aaccaacttc catctgccaa
    72241 aatcaactct ggtcatgttg gtttctgcct ttgcaggccg tgaattagtc ttagatgcct
    72301 accaccatgc catccaagaa cactaccgct tcttcagttt tggtgacgcc atgtttattt
    72361 attgagaaag aatttctcta attcttctaa taccaataaa tcgctaagat attatttcaa
    72421 agaacatcta caattgaaac tctagctagc tgtagaagac gcctagtaca ttgaaattaa
    72481 aatgcttccc cctagcttcg aaaatattgc catagattgc gttgactctc caaattgatt
    72541 catctatatt ttatttcagc ttcctatatt ttcttcgctg tttgtaaatc aaaatgcaag
    72601 acacatgagt agcaccatat ttgttactct tatctgtcct ctcaagagac tattatgagt
    72661 tatttcagaa tcattcacta ctttgaccct gactctcctt agtctcaaaa tcaaagactt
    72721 atactcttca aaaatctctt caaaccgcgt caacgtcgcc ttggattata tatgtgactg
    72781 acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgc gactagtttt
    72841 ctagtttgct ctttgatttt cattgagtat taaacaaaaa gtgaacaaat ctgaattcta
    72901 atgtacagaa gactaggctt gttcactttt ttatagtcgc tataagatga ccttatctat
    72961 agctttttat atataattat atattcagac atactattat caattttgtc gcagggagga
    73021 atctgttaac gcacccattc accattatca ttgactctat agccatctat acttgtattg
    73081 accgctaact cacccgatgt atttacataa taccatttac caccaacttg gaaccattga
    73141 ttgactttca tagaaccgtt gctgttgagg tagtaccatg aaccattaac ttgtacccaa
    73201 cctgttgcca tggaaccatc agtattataa aaataccaca taccattttc ttgtttccag
    73261 cctgttgttg gagcaactgc tttagctggt tctactgcta catctgttcc ttggttagat
    73321 gtaacagata caggatacga aggaatagat gattgctcag gaacaacaac tttttcaggt
    73381 tctctcgtcc ctctccttat acgtcttttt accatctctt tagtaatttg acgagaagta
    73441 gtttcttcaa ttgttccatc acgttcatct acagtataga ttgtagtaag agtaatttac
    73501 caatttctcc tacttcttct acttcttgac ttttatcaag agttgggcca tcgagatatt
    73561 ctgtttcgat tgaaatttct tggacaagaa cttggggctt ggttcctttt ttaacaactc
    73621 ttgtttgaga gtcttctttt tgacttaaag tactctcagt tacttgtcca ctctttccat
    73681 ctacatcata agttatcgtt gtaactgttt tcccattctt tcctagagta atctcttgct
    73741 cctgtcctgc agaaaggtca ttgtctgctt catatttagt agcaaatgga acaagaactt
    73801 cttcaacctt gcttttagct ggaactttga taactgtatc cgtggcttct tttctatcaa
    73861 cagtaacctt ttcggtaaca tgaccagtct ctggattaac atcgtaggtc cttgtcgtgg
    73921 ttacatagcc atcctctccg tcaattgtaa catgattttc actacggtct tttgtttcat
    73981 ctttttcaaa acgaattcgc gtacttgaaa ttttcttggt tactacctta ggtttagtcg
    74041 ctacttttac aataatatcc ccattgtcag cgtcatcata ctctattccc tcttctttat
    74101 ctctagtatc atctctgaca tattgaatcc catcagcagc atgagcaaaa cttgtattca
    74161 gattcctcct aaaaataaag ttagcccgat taccgcagaa ccaaaaatct ttccgagttt
    74221 acgtattgca tagcgcttat tagtattaga ttttgccatt acatcctact tctagtatag
    74281 catcttttct atcaaacgtt aaacaatata ctttatatat aaaatagact tagaatgata
    74341 tatttactat tgaactaaca ctttaactat atcgtaatca atctcatata taaaggattg
    74401 cagacatctg atctaaatac atgctaatat atttagatac aaacattcca acttgataat
    74461 tttcactcat ctttcatcat tccttacaca acgatgcagt ataaatagaa tagttttctc
    74521 atcagaatga gactatttta atattagata atttgataga aaaacataaa taaaattggt
    74581 tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac agctaggatt
    74641 acactataaa aagtacatta ccacctgttc ggctggagaa cctagtcgat tagctccctc
    74701 ttagttacaa gcttcaagcg attttttaac taatactaaa ccagattaaa gaaggaacta
    74761 gagcatctgt cttgtaataa tcaatatgct attttaaaat tgcaaataaa cttggaatgc
    74821 taattattat atttacaata aatagttgac ttcgatagaa acagaaaata gaattcaaca
    74881 ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc tctctacacc
    74941 attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac ctgaagctgg
    75001 gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa aacaaaagtc
    75061 caagacagct ttcaaggcct ctgtcatcat accatgtccc cagtaaacct tgcctagcac
    75121 atagccgatt tcacagctta aatcagcctc gtctatctta acgatgctga tatctcctat
    75181 cacttgctct gggttttctt ttagacaaat ggcccatttg taatagttga gattagtata
    75241 ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg acatcaggat ggggatccca
    75301 ggtaacatag gtcaaattct cagcggatga agcccaattt tgaaacatag cttctgcatc
    75361 actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg taccgataga
    75421 tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc tcaactcagt
    75481 aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc tggtttgaaa
    75541 tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac gatgaaatcg
    75601 aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg gttcaagatc
    75661 ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct ccaatggagg
    75721 tttttactcc caaaagtcat caaatacggt gatgggtaag tggcgtttgt gttggccttt
    75781 gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta
    75841 gtcgtcaatc tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc
    75901 ttcttctagg tctgctgttg ggattttttc ataaagggct ggctctgcgc caagtttctg
    75961 caagagctgt tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc
    76021 gtcaccaaac ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac
    76081 cgctccgcta tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat
    76141 attccccttg ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatagc
    76201 atcagctgac tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc
    76261 tttttgagca tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt
    76321 gtagctgtcg tctcccgttt cagctcgcag ttcttctata gctaattgcg ccaaacgtcc
    76381 tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca aagtttttta ggaagggatg
    76441 ttttttcaga tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat
    76501 cactggtttg acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct
    76561 tcaccaaggg cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca
    76621 cgtgccaaat ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac
    76681 ttgtcaaatt ctttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact
    76741 aatattcctt ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc
    76801 ttcttgatgt atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc
    76861 acaccatcat aagtgatgta gtcaccttct gacttgcctt tttcacgact ggtaatgcgc
    76921 cacacctgct tcttacctgg cgtcgacact ttttccgcat tattagacag cttaatcgta
    76981 ttgcgcatct gaccagtttc atcttcaatt gcaacaatct tgtaaaccgc cccaagagcc
    77041 ggctggtcat aggctgtaat cagcttggta cccacacccc agacatcaat cttggccttt
    77101 tgcatcttga ggttaaggat ggtattttca tctagatcat tagaagcata aatcttagcc
    77161 tctgtaaatc cagcctcgtc cagttgctga cggactttct tagaaatgta agcaatatcc
    77221 ccagagtcaa tccgcacacc cataaagtta atctgatcac ccagttcacg cgccacctga
    77281 atggcagctg gtacaccgat gcgaagggta tcataggtat ccacaagaaa gacacaattt
    77341 ttgtgggtcg cagcgtaagc cttgaaagcc tcatagtcat tgccataaac ctgcaccaag
    77401 gcatgggcat gggttcccaa aacaggaatg tcaaagagtt tacccgcacg cacgttgctg
    77461 gttccattgg cgccaccaat caccgctgca cgtgttcccc agatggccgc atccatttct
    77521 tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga
    77581 gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc
    77641 aactgacatt gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa
    77701 tccccttctt gggcagaacg aacggtcaac tccaacttga aattgcaaag gtaatccaag
    77761 aacgccccat gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag
    77821 tcttcaagat agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa
    77881 ggctgttggc ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag
    77941 taaacctgca tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga
    78001 tacatacttt tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt
    78061 attccaataa attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag
    78121 ctattctcca ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc
    78181 atagctctta agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat
    78241 gacccaagca gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa
    78301 ttgataattc tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa
    78361 aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga taacgggcgc gattgaaaaa
    78421 gtaaaatgtc cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc
    78481 taatactgaa atgatataag ataggagcga caaagcaatg cagatataga aactttcaga
    78541 tcccgcttta ttgaacagtt gttcttctct ttcgtctagt aattgataat aataaaatct
    78601 atttttcatc ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa
    78661 tagactggca gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct
    78721 ggcgtgtcac cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag
    78781 ctaattttaa ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct
    78841 actcttaaaa aatccaaaac caacacaagc tatcagctat ttattataac cccattaatt
    78901 tgcactccag tattatcttc agacgaaaat cagtatttta ggttgtttga aataaatttc
    78961 ctagtttact cttttatttt tatttagtat tagctttagt agaatctttt aaacgagttt
    79021 ttattgctta tatttcttgt ttagtttagt tggtttcata tcactattat ataatgcttt
    79081 tggaaatgag cctagtataa gtcaaaaacg tgttgaatag tgaaagcagg agcataccaa
    79141 gatgactgat ttttttactg tattttaggt atgcaaaata atactaaatg aaactaaaat
    79201 gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt agtgattagc
    79261 acaagatact gactaataga catcgtattt gaaaccacaa atagaggtaa agaataaaaa
    79321 ggaagaagtt caattgcttt gataaacaaa tcattactag tattcatcat aatcgtattt
    79381 aatatattag ggataaagag tagtaaagct actaaaatac caaataccaa gccacttttc
    79441 aatttgtata aatagaaaat gtaagataat agaaaataaa acaggactaa caaaattgta
    79501 ttgactacaa tagctactat aaaatctaat cctaaatcac ctggaatacc caacttactt
    79561 actatgacta gtaacacaat gccattcaaa gcataaataa tggaaactga gatggcatat
    79621 agaaaattag acaagacgta aatcatccga ttcttctgtt gattataaaa caaacttacc
    79681 gtattgtggg aaaaatctct actaataact cgattagcat gtataacagc cattaacata
    79741 ccgagcatag cataaaagtt tgaaatatgc ttaataccaa gcgatgtctc ttgagtcttt
    79801 agaataaaga atgtaagcaa tatcggcggt ataaacgaga taagcaaact gagatatatt
    79861 acgcctgatg aatataaatt tcttatattt tccttaagaa aattcaattt atttaatttc
    79921 atgattataa ccttccttta ttttgaacga tttaagtaaa tatctttaag cgtctctttt
    79981 ttagtttcaa aatcaactac tttaatagag ttttcgttaa aaaatttaaa aagctcacta
    80041 ctttgaatat tcccagacat agtaattctc agtccctctt cctgaacaat atccccaaat
    80101 tcttgtttgg taatgaaaat gtctctatct gtagctgatg aaaaagctat ctcaaacaag
    80161 aaattatgac tatcttttcc tactttttga aatgtcaaaa gcccgctctc caagaaaaga
    80221 accctctcac aaatttcttc aatgtcttct aatttatgac tcgatattaa aattcccacg
    80281 ttttcattta aagctaattt ttttagaacc gctaaaacta tttgtgatga ttcaatatct
    80341 aaaccattag tcggttcatc taaaatcaat atatcaggtt tcgtaacgag agttagaagc
    80401 aaagctaatt tttgttttgt acccaaagaa taggtcttta cttttttatt aatagactga
    80461 gtcaaatcta actcttggat caaacttcta aatctttctt gattgtagtc aacaccatat
    80521 aaatttgaca aatattttaa attctctaaa cctgttttag ataaaaataa ttttggttct
    80581 tcgattaaat acccaatatt atcactgctt ataatattac ctgaagtcgg ttgattattc
    80641 tgaacaagaa ttttcatcaa cgtactctta ccaactccat ttctccctac tagaccaaca
    80701 atttcaccct tgttaagtgc aaaatttata tctttgagaa tgattgaatg accataatgc
    80761 ttacttacat ttataactta cattttttat tcctccatta atattcatgg tttgctcttt
    80821 gattcttatt gagtttaaaa agttgcgcct ctttttaaca acattatatc atatatctaa
    80881 cttaatgcaa tatataaatg tcattttgta aaattttatt aacaaaaaac tctctacaac
    80941 aaaataatag agagttttct gcttattaat ttttttcaaa atatctaaac atcacttctt
    81001 tgtttaattt gataggcttt gatacctaag ctccgacttt atcacttaaa aaataaaaaa
    81061 ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg tttaagtgtt
    81121 gtatatggag ctttgcataa ttttttaaaa ctaaacaact acattaaaca cgaactgtga
    81181 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    81241 ctcctgattg aacgggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    81301 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    81361 aacctggacc ataaaactca acttggtccc cttcgttaat gacatttcgt tgacgaatag
    81421 ttgctgtttg tgccgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    81481 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    81541 tagccagttc acgttgggca accttccaca tctcgtccac caagtcttgt ttgatagctt
    81601 caaacttttc aggactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    81661 ttaatacata gtgaatagac tccatacgtc cttcgatttt tagactgtcc acaccatttt
    81721 caatcatatc tggaatgtgg tcaatcatag acatgtcaac ggctgacatt gaaaattctt
    81781 ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    81841 acttccaacg gcatgactga gaacatccac cacggttggc atcacgcata ctctagacgg
    81901 attgttttga caattctaat cttttagact ttgcataata actgttaaac agttgaaaat
    81961 tgacccagtt ttaacaagta gtcaaaatac cagataaagg aaaaaagtct ttaaaatctt
    82021 aaaaacgcat agtatcaggt attgaacaat cttgatatta tgcgttttat tgtgggaaga
    82081 tttacttcat tttctcttgg aattgagttt tctcctactt caaaactaga tgatttgcta
    82141 tttaaaatag cgttccttat gattttggca acctggatta aagcgagaaa aacaaaaggg
    82201 gcaacttaag ctttctttat attgcttata tgttagtagt tttagacaaa caccacataa
    82261 aataggctta tcctgtatca aagataaggg atacggctca aaagggtgat tttctaatga
    82321 atcatgacac cgataacaag cataatactt tttacaatca tagcattgta aagcaataat
    82381 atccagcttg ctatggtaat gaatgcatct tgtttgctta tccactaaga aaccctgtgc
    82441 ctctatcatt tccttttcct ttcttaagct cgaactgtga cgctggttcc atcttcctta
    82501 taaagattga tgagtccttc ttttaatgca cgaaccatgt ctcctgattg aacgggttga
    82561 ggcaccttaa tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg
    82621 gcatcatgca aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca
    82681 acttggtccc cttcgttaat gacatttcgt tgacgaattg ttgctgtttg tgccgcatca
    82741 tcataagaaa ccacttcagc gacaaacttg tactcaggga ttttacggcg agcaccaaac
    82801 aactgctcat tttcagatgg tataccgtag tagaaacctg ttgccaattc acgttgggca
    82861 accttccaca tctcgtccac taagtcttgt ttgatagctt caaacttttc aaaactttca
    82921 agataggcat ccacagccgc cttgtagcag ttggttactg ttgatacgta gtgaatagac
    82981 ttcatacgtc cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg
    83041 tcaatcatag acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa
    83101 ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga
    83161 gaacatccac cacggttggc atcacgcata ctcatgtggt ttgaaagagt acaacgtcca
    83221 gagtatgaaa tacacatagc tccatggaca aaggcttcaa tttcaacatc tgtacgtttg
    83281 cggatttcag ctaattcttc cattgaaacc tcacgcgcta aaacgacacg agtcaagcct
    83341 agctctttcc agaactcaag ggtttcatag ttagtggcac tggcttgggt agaaaggtgg
    83401 atttcaaggc ctggtgcttc agtcgctgca atcataatca aggctgggtc agatacgata
    83461 actgctgcaa tcccgatatc acgcagttta cggaaccact caccagcacc agcttcattt
    83521 ccttcgtgca taaccatatt agccgctaca tagaccttgg caccatactt ggccgcaaac
    83581 tgcacgcctt cttccatctg ttcgaaagta aagtttcccg cacggctacg aagaccatag
    83641 gcctgaccac cgataaagac agcatctgct ccatactgaa cagctacctt tagcttctct
    83701 aaagtccctg caggtgataa aacctcagga cgttttaatg tttttgtcat aatttctcct
    83761 atttgcaata taaaagtttg acatttttcc ttctcatttt atagtaaata aaggataaaa
    83821 tcaagcctag acggattgtt ttgacaattc taatctttta gactttgcat aataactatt
    83881 aaacagtcga aaattacccc agttttaaca agtagtcaaa aagtctaaaa aagtaaaaac
    83941 cagtatccca agatactgac tcgtaaaaat atataaatta gtccttagat gactactccc
    84001 actctgttgc tcctataatg gaaaaggatt gatacagtct agaatatcgc ttttttattt
    84061 attattatga tataaaactg ttagaattga ttttttgttt tatacccaaa tatgaataga
    84121 gacgtagcta ataagttgaa taacatattt ggaaaaatga gaaatagcaa tattactaga
    84181 acttttagaa acaatcaata tttaaaaaga aaaaagctca aagaatttat taaaccatgt
    84241 tataatagat atagctataa ttttatttat aacaagagga tagaaatgac cgaattagaa
    84301 agaaaaaatc gaaaaattag ctaagaaata ttctgataac ttaaacatca aagttcaaga
    84361 gagagttcgt gaaatggcaa atgataataa gagccattat ttgatataca gagttttagg
    84421 tatttcattt gaagaaggag aaaatatcga tttgtatcaa aataaaggtc gttttttata
    84481 caaatatgct ggttcatttt tagaagaagc tgcagtacta tcctttaacg aaaaatttgg
    84541 tacagaaaat acttaaaaag ttaacattcc taattctgaa agtacaaaac ctaagacttt
    84601 tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa ataaaatggt gggatgcaac
    84661 tacagatgga gaccatataa ctaaagaaca cactagaata aaagttattc ataacaaagg
    84721 atatatacca attcggttaa tgttctacta tccaaataga actcaagcta taaaaattca
    84781 gcaaacttta gaaacattgt ataacggtat tggagggaaa tattatggag attctgcctg
    84841 ggaacattta agagcagtga ccggtattga tttacttagt attctaacag atattgcaaa
    84901 taaaaaacag gggtaaaatc aaaatgacag tattaaaagg agataactta gaaatattaa
    84961 aaactattga atcctcaagt attgatttaa tctatatgga ccctcctttc tttacacaga
    85021 aaacccaaaa attatctaat aacaaaaata ttatgtattc attcgaagat acgtggactt
    85081 cgattgagga ttacaaagaa tttttgtctg taagattaga agaatgcaaa agagtgctaa
    85141 aaaatagtgg cagtattttc gttcattgtg ataaaattgc aaatcatcat attagattaa
    85201 ttttagataa tatctttgga gcagatatgt ttcaaagcga aattatatgg aactataaac
    85261 ggtggtctaa ttcaaaaaag ggattattga acaatcatca aaacatttac ttttattcaa
    85321 agtcaaaaga ttttaaattt aatacaattt ttacagagta ttcttctact acaaatatcg
    85381 accaaatact agtggaacga aaacgagatg gaaactctaa aactatatat aaggttgata
    85441 ataatggtaa ctatattcta gcaaaagaga aaaatggagt tcccctttca gatgtttgga
    85501 atataccatt tcttaatcca aaagctaaag aaagagtagg ttatcctaca caaaaaccta
    85561 ttctgttatt agaacaaatt ataaagattg ctactgataa aaatgatata gttttagacc
    85621 cgttctgtgg aagtggaact actttagtag cctccaagat tttgaataga aattatatgg
    85681 ggattgattt atctgaggaa gctatcaata taactcagca acgtctggaa aatgttataa
    85741 aaacaagttc aaatttattg aataaaggaa tcgaagcata tagaaccaaa actgaggaag
    85801 aggaaaacat tcttaaatta ttacaggcaa aaattgttca aagaaataaa ggaattgatg
    85861 gttttttacc taaacatttt caaaaaaaac cgatacctat aaaaattcaa aaaaataatg
    85921 aatgtctgaa tgagagtatc tctttattac agaatgctat aaactccaaa aaacttgatt
    85981 ttggagtagt tataaaaact cattcagata atttattatt tgattttgat acgattcctg
    86041 aaaatataat agtagttgac cattttgaac ttacaatcga aaaatggtta agtaaaagtc
    86101 aacagttact atagtttgca aattatttac agaaagaaca aaaaatgctc tgaaacactg
    86161 atttcaaggc attttttgtt agtttaaaat tactcccatt cttcttttcc aaacatacaa
    86221 tatatccaaa accattcaaa atactagatt ctatttttta taatatcact aaatccacct
    86281 aattatagga cgttttcaga tttttagtcc cgtcccagtc ccagtaccgg agaaatattg
    86341 ttttaatata atatctcttt ttgtcttcta agctcttaaa agcaaaagaa caagtaaaga
    86401 gtcaagacaa ggataaaaag tccatattag ggcaaataaa aagctttaag acagatgaca
    86461 aatctaagtc aaataagaaa gaccatagca aaggtgcaga gagataaata ttggcggtct
    86521 tcggactgcc tttatttttt tatccatttt tcaaatcaaa tttattcaga ctatatatgc
    86581 acatatacac ttaaattcat ataaaaacat ggcttgtaaa aaattacttt aatcacaata
    86641 atcgcattta aaattgtgat gtttgcaagc taaattacgg acttcacttg gaagttttcc
    86701 cttgtatctt ttataataga tagaaaattt gctggcagat gaatatccaa cagattctgc
    86761 tatctctttt ataggtagtt cagtgtttaa aagaagagtt tcagctacat tcattctttt
    86821 tctttgagtg tactctgtaa tgctttgaca atatttttcc ttaaataaat tttttaattt
    86881 agtaccactc attttagata ttttttcaag cgtgccttga tttacattcg ttgcaaaatg
    86941 atcatctaag aatcttgcta catcttcaag tgctttatca tcatcaattt caattttata
    87001 tttttttcta tttaagtatg tgtcaattac tatacttatc cattcatttg cctttgcttt
    87061 aaagaaaaaa tcagcggcag gagcgtccat cttacaattt aatatttcca ttgccactct
    87121 ttctaaggcc tttgtaagta ttatttgatt cggttgaagc aaggttgaat aaaaagattc
    87181 tggattaatg ttaatagatg ctaaatgttt ttctattagc tcttttttaa aaccaatgga
    87241 aacagcaaga taacaacaat tctcgtgtaa taaaaaaaca aaatcatctt ttatattatc
    87301 aaaatcaaaa gtacataaag agtttgcggt aatagtttga tacggattaa acttttctcc
    87361 gtttgcactg acaatgtaac ttgaataaat tgaaacatag tctgacatac tataagtgct
    87421 attttgaact acttcctctt tgatataaaa atcatgtata tcgataatga agctgcctcc
    87481 ttcataaaac caatataggc cttctgcata agttgaattc tcttttttcc aacaaaatgt
    87541 atgacctgca cttgaatact tctcattgtt tttacattca tctactttca tataatcttt
    87601 tacaaaatca taatatgaca taacacacta tcccttttag acaatattcc aattagcctt
    87661 attaattcaa aactattgta ttagtaatta taacagatgt ataatagaaa agcaatgata
    87721 gatattatca attaagcgaa tttatatcta aaagggatat taaagaaagg agatatgctt
    87781 atgaagattt acaaaaaact atttgcttat gtccaagata agaaatatct tggggttttg
    87841 gccataattt tttctgctat atctgctcta cttacagtat atggatatta tttaatctac
    87901 aaatttctag ataagttaat aattaattca aatttatccg gtgcagagag tatagcatta
    87961 aaatctgtta ttacactaac aagtggagcg atattttatt ttgtctcagg aatgttttca
    88021 cacatcttgg gatttaggct tgaaacaaat ttaagaaaaa ggggaattga tggcttagag
    88081 aaagcaagtt ttaggttctt tgacttaaat ccatctggtc aaataagaaa gatcatagat
    88141 gataatgcag cacaaactca tcaggtggta gcacacatga ttcccgatag ttctcaggca
    88201 ataatcacac ccgtacttgt acttgcactt ggctttatag taagtataag agttggcata
    88261 attttgcttg ctcttactat aattggcggc ttaattttag gggcaatgat gggcgagcaa
    88321 gaatttatga agatatacca agaatcccta tctaaactaa gtgctgaaac tgttgagtac
    88381 gtgagaggaa tgcaagttgt aaaaatattt aaagcaaatg tagagtcttt taaaagcttt
    88441 tataaggcga taaaagatta ctcaaagtat gcttatgatt attccctatc ttgtaaaagg
    88501 ccttatgttt tgtatcaatg gttatttttt ggactgattg caattttaat tattcctata
    88561 gtttatttta tgactagctt agctagcgca aaggtgattt tacttgagct tatcatgatt
    88621 ttatttttat caggagttct ctttgtttca ttcatgagaa tgatgtggta ctccatgtat
    88681 atttctcaag gaaattatgc agtagatact ttagaggcgc tttacgaaga tatgcaaaaa
    88741 gacaaattag tgcatggtaa tatcaataat tttaaaaact ataatataga atttgagaat
    88801 gttagctttg cttataatga taaagctgtc attgaaaatt tatcctttaa tttagaagaa
    88861 ggaaagtcct acgcacttgt cggttcatct ggatcaggca aatcaacagt agcaaaactt
    88921 atatcaggtt tttataatgt taataaagga agcataaaga taggcgggat agcaataagt
    88981 gaatattctg acgaagcctt aattaaagcc atttcctttg tttttcaaga ttcaaaatta
    89041 ttcaagaaga gcatttatga taatgtagct ttagctaata aagatgcgac gaaagatgac
    89101 gttatgagag ccttaaaatt agcaggatgc gatttaatat tagacaaatt cccagaaaga
    89161 gaaaatacaa tcataggctc aaaaggtgtt tatttatccg gtggagaaaa acaaagaatt
    89221 gcaattgcta gagcaatttt aaaggattcc aaaattatta ttatggatga agcatcagca
    89281 tctattgacc cagataacga gtttgaattg caaaaagctt ttaaaaatct tatgaaggat
    89341 aaaacagtta tcatgattgc acacaggcta tctacaatta aagaccttga tgaaattatt
    89401 gtcatggata gtggaaaaat tatagaaaga gggtctgaca aagaattaat gtcaaaagat
    89461 acaaggtata agagcctgca agagatgttt aacagtgcga atgaatggag ggtttcaaat
    89521 gaaagagttt tataaaaaaa gatttgctct tacagatgga ggagcaagaa atttaagtaa
    89581 agcaacactg gcttcatttt tcgtttattg tataaacatg cttcctgcca tattacttat
    89641 gatttttgct caggaagttt tggaaaatat gggcaaaagc aatggctttt atatagtatt
    89701 ctcagttttg actttgatag caatgtatat tttgctttct atcgaatacg ataaattata
    89761 taacacaacc tatcaagaaa gtgcagattt aagaataagg acagcggaga atttatcaaa
    89821 attacctcta tcttactttt ctaaacatga catttccgac atttcacaaa caatcatggc
    89881 tgatattgaa ggcatagagc atgcaatgag ccactcaata ccaaaggtgg gcggcatggt
    89941 actgtttttc ccattaatat ctgtaatgat gctagcgggc aatgtcaaga tgggtttagc
    90001 tgtaattatc ccatctattt taagctttat atttatacct ttatctaaaa aatatcaggt
    90061 taatggacag aatagatatt atgatgtctt aagaaaaaac tcagaaagct ttcaagaaaa
    90121 tatcgaaatg caaatggaga ttaaagcata taatttatcg aaggatatta aagatgactt
    90181 atataaaaaa atggaagata gtgagagagt acacttaaag gcggaagtaa ctacaatttt
    90241 aactttgtct atatcttcaa tatttagctt tatatctctt gctgttgtga tatttgtcgg
    90301 cgtaaatcta attattaata aagagataaa ttctctctac cttataggat atttactagc
    90361 tgctatgaag ataaaagact ctttagatgc atctaaagag ggcttgatgg aaatatttta
    90421 tttatcgccc aaaatagaaa gattaaaaga aattcaaaat caagatttac aagaaggcga
    90481 tgactatagc ttaaaaaaat ttgatattga tctaaaagat gttgagtttg cctacaataa
    90541 agacgcaaaa gttttaaatg gtgtaagttt taaagctaag caaggagagg tcactgcttt
    90601 ggtaggtgca agtggctgcg gtaaaacaac tatcttgaaa cttatatcaa gactttatga
    90661 ttatgacaag ggacaaatct taatcgatgg caaagatata aaagaaatat caacagaatc
    90721 tctttttgat aaggtctcta tagttttcca agatgtggtt ctctttaatc aaagcgttat
    90781 ggaaaatatt agaatcggaa agcaagatgc aagtgacgaa gaggttaaaa gagcagcaaa
    90841 acttgcaaat tgcacagatt ttatagaaaa aatggataaa ggtttcgata cagttattgg
    90901 tgagaacgga gctgagctat caggaggaga aagacaaaga ttatcaatag ccagagcctt
    90961 cttaaaagat gcgccgatat tgatcttaga tgagataaca gcaagccttg atgttaacaa
    91021 cgagaaaaag attcaagagt ctttaaataa tttagttaaa gataaaactg ttgtaatcat
    91081 ttcacataga atgaaatcca tagaaaatgc agacaagata gtagttcttc aaaacggaag
    91141 agtagaaagc gaaggtaagc atgaagagct tttacaaaaa tcaaaaattt acaaaaattt
    91201 aatagaaaag acaaaaatgg cagaagaatt tatttattag gaggactaca atggataata
    91261 aaaaattaaa agtaaaagat ttagtaagca tcggtgtttt tggcgtaatt tattttgcct
    91321 tcatgtttgg agttggtatg atgggcttga ttccaatatt gttcttaata tacccgacag
    91381 tattagccat agttgcagga actgttgtta tgttatttat ggctaaggtt caaaagccat
    91441 gggcactatt tatatttggt atgatatcac cacttgtgat gtttgcagct ggtcatacct
    91501 acgtagttgt ggttttatca cttatagtaa tgataatagc agaattaatt agaaagattg
    91561 gtaattataa ttcatttaaa tacaatatgc tttcttatgc aatcttcagc acatggatat
    91621 gtagctcttt aatgcaaatg cttttagcaa aagaaaaata tatggagtgg tctttgatga
    91681 cgatgggaaa agattatgtt gatgtgttag aaaagttaat aacttatcct catatggctt
    91741 tagtagcctt aggtgctttc ttaggaggaa ttcttggagc atatataggc aaggctctat
    91801 tgaaaaaaca cttttcaaat ggattatatt gtgtgggata ctttactcct tgcctaattt
    91861 tatggtgcta tctgaattaa accctatagt taagatgttt ttgagtatac ctattgttat
    91921 tagaatgttt attttaccat ttatggcagc aagctttatg ataaagacct cggatgtagg
    91981 cgcaataatt tcatcgatgg ataagcttaa gatttcaaag aatgtatcca tacctattgc
    92041 ggttatgttt agattcttcc catcttttaa ggaggagaag aaaaacatca aaatggctat
    92101 gagagtaaga gggataaatt ttaaaaaccc agtcaaatat cttgaatatg tttctgtgcc
    92161 actactcatt atatcatcta atatatcaga tgacattgca aaagcggcag aaacaaaggc
    92221 aatagaaaat ccaattgcca agaccagata cattcgcgta aagatacagc taattgattt
    92281 tgtttatgtt ttagcggttg ctggacttat tgtgggaggc ttaatatggt tgaaataaaa
    92341 aatttaagtc ttgattatgg tgaagagcat atattagatg atatatcact atccatagcc
    92401 gagggagagt gcgtgctatt tacaggaaaa agtggaagtg gtaagtcatc tttaataaat
    92461 tcaatcaatg gactagctgt aaggtatgat aacgcaaaga caaagggcga aataattatt
    92521 gatggtaaga atataaaaaa tttggaactt tatcaaatct caatgcttgt ttcaactgtt
    92581 tttcaaaatc ctaagacata tttttttaat gtcaatacga cattagaatt attattttat
    92641 ttggaaaata tcggtcttgc aagagaagag atggacaggc gtttgaagga tatgcttgag
    92701 atattcccga taaaaaatct tttgaacaga aatatattta atctatccgg cggtgaaaaa
    92761 caaattcttt gcattgcagc ttcttatata gcaggtacaa agattatagt tatggatgag
    92821 tcttcatcga atttagatat taaaagcata agtgttttgg caaagatgct aaagatatta
    92881 aaagagaaag gcataagcat aattgttgca gagcatagaa tttattattt gatggacata
    92941 gttgaccgtg tatttttaat agataaagga aagcttaaaa aaacttatac tagaagtgaa
    93001 tttttaaagc tagataaaaa tgaattaaat gctttaagtt taagagataa aaaattaagt
    93061 aaattaaaag ttccttattt aaaagaaggt ggagagtatc agataaaaaa tcttagctac
    93121 aaatttactg atgatgagtg cttaagctta aaagatattt cgttcaagct tgggaaaatt
    93181 tatggcataa taggatccaa cggacgagga aaatcaacgc ttttaagatg tttaataggt
    93241 cttgagaaaa aatcaaaaga agaaatttat tttaagggag agaagctatc taaaaaagaa
    93301 agactcaaaa actcttcact tgttatgcaa gatgtaaatc atcaattatt cacagatgaa
    93361 gtattcaacg agcttagatt aggagtaaag aattttgatg aagaaaaggc gaaaatcatt
    93421 ttaaaagatt taggcctgga cgaatttatt gaaaggcatc cgatgagttt atcaggaggg
    93481 caaaagcaaa ggcttgcaat agcatctgtt atgtgcaaga attctccatt tgtctttttt
    93541 gacgaacctt caagtggtat ggattattcc aatatgataa aaatatctga actgattaat
    93601 aagtataaaa ccatggataa aataattttt attgtttccc atgatataga atttttaaat
    93661 gaagtggcag atgaaatttt tgaattataa aatagagtct gttaaacatg tctatagaac
    93721 tggtaaattg tctaaaaatt taaaagatac taacacatat tgatatttat tagaaaatta
    93781 acttcaggat ttttacagta tttataaact ttataatatg tatttatagt attaataatt
    93841 tccatatctt tagggaaatt ctttatttac ttaccataat taaagagatg agagataaat
    93901 atcggcagtc ttcggactgc ctttattttt ttacttaatt taatgcagta aatcatacga
    93961 ttgaaaggaa tctgctttat atgctataat taggtagtta atctatacat ttagaaaggt
    94021 aaaatataga attggagaat gatatgggat tttcatataa taaattgtaa ccg
//
LOCUS       DBEJNA010000002        92454 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEJNA010000002 DBEJNA010000000
VERSION     DBEJNA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 92454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.02"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            148..804
                     /locus_tag="ACL3JB_000095"
     CDS             148..804
                     /locus_tag="ACL3JB_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0684913.1"
                     /translation="MPTALGYVSIDLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            794..1117
                     /locus_tag="ACL3JB_000096"
     CDS             794..1117
                     /locus_tag="ACL3JB_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGR0684914.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1221..2051
                     /locus_tag="ACL3JB_000097"
     CDS             1221..2051
                     /locus_tag="ACL3JB_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0684915.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2205..3059
                     /locus_tag="ACL3JB_000098"
     CDS             2205..3059
                     /locus_tag="ACL3JB_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0684916.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNAITIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3159..4532
                     /locus_tag="ACL3JB_000099"
     CDS             3159..4532
                     /locus_tag="ACL3JB_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0684917.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4525..5586
                     /locus_tag="ACL3JB_000100"
     CDS             4525..5586
                     /locus_tag="ACL3JB_000100"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0684918.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5588..6280
                     /locus_tag="ACL3JB_000101"
     CDS             5588..6280
                     /locus_tag="ACL3JB_000101"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0684919.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6310..6879)
                     /locus_tag="ACL3JB_000102"
     CDS             complement(6310..6879)
                     /locus_tag="ACL3JB_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0684920.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7014..7628
                     /locus_tag="ACL3JB_000103"
     CDS             7014..7628
                     /locus_tag="ACL3JB_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0684921.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7606..9276
                     /locus_tag="ACL3JB_000104"
     CDS             7606..9276
                     /locus_tag="ACL3JB_000104"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0684922.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9288..10574
                     /locus_tag="ACL3JB_000105"
     CDS             9288..10574
                     /locus_tag="ACL3JB_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0684923.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10626..11159
                     /locus_tag="ACL3JB_000106"
     CDS             10626..11159
                     /locus_tag="ACL3JB_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0684924.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11237..11707
                     /gene="nrdI"
                     /locus_tag="ACL3JB_000107"
     CDS             11237..11707
                     /gene="nrdI"
                     /locus_tag="ACL3JB_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0684925.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12000..13262)
                     /locus_tag="ACL3JB_000108"
     CDS             complement(12000..13262)
                     /locus_tag="ACL3JB_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0684926.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13572..14030)
                     /locus_tag="ACL3JB_000109"
     CDS             complement(13572..14030)
                     /locus_tag="ACL3JB_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0684927.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14027..14467)
                     /locus_tag="ACL3JB_000110"
     CDS             complement(14027..14467)
                     /locus_tag="ACL3JB_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0684928.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15051..15917
                     /locus_tag="ACL3JB_000111"
     CDS             15051..15917
                     /locus_tag="ACL3JB_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0684929.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYRVNQLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYIADITE"
     gene            16067..16201
                     /locus_tag="ACL3JB_000112"
     CDS             16067..16201
                     /locus_tag="ACL3JB_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684930.1"
                     /translation="MRSLFKKIVAVLVIGLILLGIARTPQVHKIARGIDPGPANGQAL
                     "
     gene            16640..18070
                     /locus_tag="ACL3JB_000113"
     CDS             16640..18070
                     /locus_tag="ACL3JB_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0684931.1"
                     /translation="MQILISEVNVTSFGITREILKKMDFNFSKMGSEEAKFLIFPELP
                     RGGELSLTARQSYDSQLRYSMLPRVEDIMKKIVNQLREHLKILDIELSDLSYLSEGDQ
                     FILKELSSHVKINIKITPIKKIRYVYEDIFLNQSAEELHELGLKYLSAGDLWASKKIF
                     TYLVNKYDNRRDVFKLATTYNMLLETEKAEYYYNLYKHDGKVDHIVAANYMLAMLYAR
                     HHPKYLQDDQKAIVLLNEAYDLIKDKVTLESIFNRNGYALLLFKMGKVEETIILLKRC
                     LNQIKQLDNSSSSVVLHESVLWFNLYQCYVTIGDNTNSRKTFYILKNMDPLFIEYYLE
                     YSRNLLETDVENFLEFIESMPHHSNNFAEKYSLLGYYFRGTAKSLEYFSKAFELSNRT
                     FSFWYDITYELTEFNLYNEAYNNLPLLNNKLYELNDEDLLNYILISAEIFYNLDRLDE
                     FKRTIEIGYRIFPDSESIKEIIENAE"
     gene            18067..19242
                     /locus_tag="ACL3JB_000114"
     CDS             18067..19242
                     /locus_tag="ACL3JB_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0684932.1"
                     /translation="MKRYKTLFIKYPDSFQFLVFNILFYLSMSLSRSVHSIWFDLNGS
                     LLNYSISYSAMAFSGMFAGILGRRINYFNLRNLIRIGVILYSIGLLLRLFPNDWLISL
                     ISGLISGIGAATIILLLRTWAVGIGKEKDRVVTISLKRFSSSLGTSIGGILSGILLYC
                     LIYFFHSMAYPIVLASASMLCLVTFFCIPKIDSFVDKSERAERILESSNYMKKRIIFF
                     GIFSGLIASIFSPYLPVILRRQEISEVFIGPVLTILSLLTIYFSSIFSSRKVDNHKQG
                     YYILSELLISILTLLFSFHLKYYLVITILIIRVFFVNLSSITQELMELSIYPKEKISY
                     FYGISQTSYFIGDTLGGFIGGWLFNQDMKYSIYLFSVLLLFNAVLFNRFYLRNNKNS"
     gene            complement(19376..20433)
                     /locus_tag="ACL3JB_000115"
                     /pseudo
     CDS             complement(19376..20433)
                     /locus_tag="ACL3JB_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681261.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21004..22953
                     /gene="mutL"
                     /locus_tag="ACL3JB_000116"
     CDS             21004..22953
                     /gene="mutL"
                     /locus_tag="ACL3JB_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0684933.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGYGISHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(23278..23745)
                     /gene="ribE"
                     /locus_tag="ACL3JB_000117"
     CDS             complement(23278..23745)
                     /gene="ribE"
                     /locus_tag="ACL3JB_000117"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0684934.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(23746..24951)
                     /locus_tag="ACL3JB_000118"
     CDS             complement(23746..24951)
                     /locus_tag="ACL3JB_000118"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0684935.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(24971..25606)
                     /gene="ribE"
                     /locus_tag="ACL3JB_000119"
     CDS             complement(24971..25606)
                     /gene="ribE"
                     /locus_tag="ACL3JB_000119"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0684936.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(25591..26691)
                     /gene="ribD"
                     /locus_tag="ACL3JB_000120"
     CDS             complement(25591..26691)
                     /gene="ribD"
                     /locus_tag="ACL3JB_000120"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0684937.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(26826..26940)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27097..27690
                     /gene="ruvA"
                     /locus_tag="ACL3JB_000121"
     CDS             27097..27690
                     /gene="ruvA"
                     /locus_tag="ACL3JB_000121"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0684938.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            27700..28263
                     /locus_tag="ACL3JB_000122"
     CDS             27700..28263
                     /locus_tag="ACL3JB_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0684939.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWRGLK"
     gene            28260..28937
                     /locus_tag="ACL3JB_000123"
     CDS             28260..28937
                     /locus_tag="ACL3JB_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0684940.1"
                     /translation="MMSNKNKGILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(29092..30123)
                     /locus_tag="ACL3JB_000124"
     CDS             complement(29092..30123)
                     /locus_tag="ACL3JB_000124"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0684941.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFKNDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(30378..31061)
                     /locus_tag="ACL3JB_000125"
     CDS             complement(30378..31061)
                     /locus_tag="ACL3JB_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0684942.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(31073..32017)
                     /locus_tag="ACL3JB_000126"
     CDS             complement(31073..32017)
                     /locus_tag="ACL3JB_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0684943.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            32149..34980
                     /gene="uvrA"
                     /locus_tag="ACL3JB_000127"
     CDS             32149..34980
                     /gene="uvrA"
                     /locus_tag="ACL3JB_000127"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0684944.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            34973..36034
                     /locus_tag="ACL3JB_000128"
     CDS             34973..36034
                     /locus_tag="ACL3JB_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0684945.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKVGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            36166..36564
                     /gene="spx"
                     /locus_tag="ACL3JB_000129"
     CDS             36166..36564
                     /gene="spx"
                     /locus_tag="ACL3JB_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0684946.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            36630..37199
                     /locus_tag="ACL3JB_000130"
     CDS             36630..37199
                     /locus_tag="ACL3JB_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0684947.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            37286..37552
                     /locus_tag="ACL3JB_000131"
     CDS             37286..37552
                     /locus_tag="ACL3JB_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0684948.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            37556..37975
                     /gene="ruvX"
                     /locus_tag="ACL3JB_000132"
     CDS             37556..37975
                     /gene="ruvX"
                     /locus_tag="ACL3JB_000132"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0684949.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGKFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            37991..38296
                     /locus_tag="ACL3JB_000133"
     CDS             37991..38296
                     /locus_tag="ACL3JB_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0684950.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            38654..39904
                     /locus_tag="ACL3JB_000134"
     CDS             38654..39904
                     /locus_tag="ACL3JB_000134"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0684951.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLDIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            39988..40419
                     /locus_tag="ACL3JB_000135"
     CDS             39988..40419
                     /locus_tag="ACL3JB_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0684952.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPAQQNTNTANAGG
                     NQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVT
                     FDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            40565..42097
                     /gene="cls"
                     /locus_tag="ACL3JB_000136"
     CDS             40565..42097
                     /gene="cls"
                     /locus_tag="ACL3JB_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0684953.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            42175..42318
                     /locus_tag="ACL3JB_000137"
     CDS             42175..42318
                     /locus_tag="ACL3JB_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684954.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            42355..43893
                     /locus_tag="ACL3JB_000138"
     CDS             42355..43893
                     /locus_tag="ACL3JB_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0684955.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            44013..46220
                     /gene="nrdD"
                     /locus_tag="ACL3JB_000139"
     CDS             44013..46220
                     /gene="nrdD"
                     /locus_tag="ACL3JB_000139"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0684956.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLVDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            46232..46372
                     /locus_tag="ACL3JB_000140"
     CDS             46232..46372
                     /locus_tag="ACL3JB_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0684957.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            46416..46922
                     /locus_tag="ACL3JB_000141"
     CDS             46416..46922
                     /locus_tag="ACL3JB_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0684958.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            46915..47505
                     /gene="nrdG"
                     /locus_tag="ACL3JB_000142"
     CDS             46915..47505
                     /gene="nrdG"
                     /locus_tag="ACL3JB_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0684959.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            47502..48119
                     /locus_tag="ACL3JB_000143"
     CDS             47502..48119
                     /locus_tag="ACL3JB_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0684960.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTSAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTAGLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            48385..48693
                     /gene="rpsJ"
                     /locus_tag="ACL3JB_000144"
     CDS             48385..48693
                     /gene="rpsJ"
                     /locus_tag="ACL3JB_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0684961.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            48910..49536
                     /gene="rplC"
                     /locus_tag="ACL3JB_000145"
     CDS             48910..49536
                     /gene="rplC"
                     /locus_tag="ACL3JB_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0684962.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            49561..50184
                     /gene="rplD"
                     /locus_tag="ACL3JB_000146"
     CDS             49561..50184
                     /gene="rplD"
                     /locus_tag="ACL3JB_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0684963.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            50184..50480
                     /locus_tag="ACL3JB_000147"
     CDS             50184..50480
                     /locus_tag="ACL3JB_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0684964.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            50498..51331
                     /gene="rplB"
                     /locus_tag="ACL3JB_000148"
     CDS             50498..51331
                     /gene="rplB"
                     /locus_tag="ACL3JB_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0684965.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            51435..51716
                     /gene="rpsS"
                     /locus_tag="ACL3JB_000149"
     CDS             51435..51716
                     /gene="rpsS"
                     /locus_tag="ACL3JB_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0684966.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            51728..52072
                     /gene="rplV"
                     /locus_tag="ACL3JB_000150"
     CDS             51728..52072
                     /gene="rplV"
                     /locus_tag="ACL3JB_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0684967.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            52085..52738
                     /gene="rpsC"
                     /locus_tag="ACL3JB_000151"
     CDS             52085..52738
                     /gene="rpsC"
                     /locus_tag="ACL3JB_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0684968.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            52742..53155
                     /gene="rplP"
                     /locus_tag="ACL3JB_000152"
     CDS             52742..53155
                     /gene="rplP"
                     /locus_tag="ACL3JB_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0684969.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            53165..53371
                     /gene="rpmC"
                     /locus_tag="ACL3JB_000153"
     CDS             53165..53371
                     /gene="rpmC"
                     /locus_tag="ACL3JB_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0684970.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            53396..53656
                     /gene="rpsQ"
                     /locus_tag="ACL3JB_000154"
     CDS             53396..53656
                     /gene="rpsQ"
                     /locus_tag="ACL3JB_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0684971.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            53682..54050
                     /gene="rplN"
                     /locus_tag="ACL3JB_000155"
     CDS             53682..54050
                     /gene="rplN"
                     /locus_tag="ACL3JB_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0684972.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            54128..54433
                     /gene="rplX"
                     /locus_tag="ACL3JB_000156"
     CDS             54128..54433
                     /gene="rplX"
                     /locus_tag="ACL3JB_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0684973.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            54457..54999
                     /gene="rplE"
                     /locus_tag="ACL3JB_000157"
     CDS             54457..54999
                     /gene="rplE"
                     /locus_tag="ACL3JB_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0684974.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            55017..55286
                     /gene="rpsN"
                     /locus_tag="ACL3JB_000158"
     CDS             55017..55286
                     /gene="rpsN"
                     /locus_tag="ACL3JB_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0684975.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            55571..55969
                     /gene="rpsH"
                     /locus_tag="ACL3JB_000159"
     CDS             55571..55969
                     /gene="rpsH"
                     /locus_tag="ACL3JB_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0684976.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            56161..56697
                     /gene="rplF"
                     /locus_tag="ACL3JB_000160"
     CDS             56161..56697
                     /gene="rplF"
                     /locus_tag="ACL3JB_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0684977.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            56781..57137
                     /gene="rplR"
                     /locus_tag="ACL3JB_000161"
     CDS             56781..57137
                     /gene="rplR"
                     /locus_tag="ACL3JB_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0684978.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            57155..57649
                     /gene="rpsE"
                     /locus_tag="ACL3JB_000162"
     CDS             57155..57649
                     /gene="rpsE"
                     /locus_tag="ACL3JB_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0684979.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            57663..57845
                     /gene="rpmD"
                     /locus_tag="ACL3JB_000163"
     CDS             57663..57845
                     /gene="rpmD"
                     /locus_tag="ACL3JB_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0684980.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            57990..58430
                     /gene="rplO"
                     /locus_tag="ACL3JB_000164"
     CDS             57990..58430
                     /gene="rplO"
                     /locus_tag="ACL3JB_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0684981.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            58443..59753
                     /gene="secY"
                     /locus_tag="ACL3JB_000165"
     CDS             58443..59753
                     /gene="secY"
                     /locus_tag="ACL3JB_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0684982.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            59904..60542
                     /locus_tag="ACL3JB_000166"
     CDS             59904..60542
                     /locus_tag="ACL3JB_000166"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0684983.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQNINDVFSDIEKVLTNLK"
     gene            60659..60877
                     /gene="infA"
                     /locus_tag="ACL3JB_000167"
     CDS             60659..60877
                     /gene="infA"
                     /locus_tag="ACL3JB_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0684984.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            60902..61018
                     /gene="rpmJ"
                     /locus_tag="ACL3JB_000168"
     CDS             60902..61018
                     /gene="rpmJ"
                     /locus_tag="ACL3JB_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0684985.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            61036..61401
                     /gene="rpsM"
                     /locus_tag="ACL3JB_000169"
     CDS             61036..61401
                     /gene="rpsM"
                     /locus_tag="ACL3JB_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0684986.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            61419..61802
                     /gene="rpsK"
                     /locus_tag="ACL3JB_000170"
     CDS             61419..61802
                     /gene="rpsK"
                     /locus_tag="ACL3JB_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0684987.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            61845..62780
                     /locus_tag="ACL3JB_000171"
     CDS             61845..62780
                     /locus_tag="ACL3JB_000171"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0684988.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            62792..63178
                     /gene="rplQ"
                     /locus_tag="ACL3JB_000172"
     CDS             62792..63178
                     /gene="rplQ"
                     /locus_tag="ACL3JB_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0684989.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            63443..63709
                     /locus_tag="ACL3JB_000173"
     CDS             63443..63709
                     /locus_tag="ACL3JB_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0684990.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            63719..65056
                     /locus_tag="ACL3JB_000174"
     CDS             63719..65056
                     /locus_tag="ACL3JB_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0684991.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMEGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            65300..65992
                     /locus_tag="ACL3JB_000175"
     CDS             65300..65992
                     /locus_tag="ACL3JB_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0684992.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(66095..67747)
                     /locus_tag="ACL3JB_000176"
                     /pseudo
     CDS             complement(66095..67747)
                     /locus_tag="ACL3JB_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(67737..68827)
                     /locus_tag="ACL3JB_000177"
                     /pseudo
     CDS             complement(67737..68827)
                     /locus_tag="ACL3JB_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(68840..69961)
                     /locus_tag="ACL3JB_000178"
                     /pseudo
     CDS             complement(68840..69961)
                     /locus_tag="ACL3JB_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(70548..71324)
                     /locus_tag="ACL3JB_000179"
     CDS             complement(70548..71324)
                     /locus_tag="ACL3JB_000179"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0684993.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            71446..72192
                     /locus_tag="ACL3JB_000180"
     CDS             71446..72192
                     /locus_tag="ACL3JB_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0684994.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            72205..73185
                     /locus_tag="ACL3JB_000181"
     CDS             72205..73185
                     /locus_tag="ACL3JB_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0684995.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            73380..73700
                     /locus_tag="ACL3JB_000182"
     CDS             73380..73700
                     /locus_tag="ACL3JB_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0684996.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            73746..74054
                     /locus_tag="ACL3JB_000183"
     CDS             73746..74054
                     /locus_tag="ACL3JB_000183"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0684997.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            74071..75369
                     /locus_tag="ACL3JB_000184"
     CDS             74071..75369
                     /locus_tag="ACL3JB_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0684998.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            75520..77958
                     /locus_tag="ACL3JB_000185"
     CDS             75520..77958
                     /locus_tag="ACL3JB_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0684999.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            77977..78645
                     /locus_tag="ACL3JB_000186"
     CDS             77977..78645
                     /locus_tag="ACL3JB_000186"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0685000.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            78663..79751
                     /locus_tag="ACL3JB_000187"
     CDS             78663..79751
                     /locus_tag="ACL3JB_000187"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0685001.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            80206..82707
                     /gene="leuS"
                     /locus_tag="ACL3JB_000188"
     CDS             80206..82707
                     /gene="leuS"
                     /locus_tag="ACL3JB_000188"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0685002.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLDVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            82846..83688
                     /locus_tag="ACL3JB_000189"
     CDS             82846..83688
                     /locus_tag="ACL3JB_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685003.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            83744..84439
                     /locus_tag="ACL3JB_000190"
     CDS             83744..84439
                     /locus_tag="ACL3JB_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0685004.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            84451..84867
                     /locus_tag="ACL3JB_000191"
     CDS             84451..84867
                     /locus_tag="ACL3JB_000191"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685005.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(85682..85774)
                     /locus_tag="ACL3JB_000192"
     CDS             complement(85682..85774)
                     /locus_tag="ACL3JB_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0685006.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            85908..86906
                     /gene="ruvB"
                     /locus_tag="ACL3JB_000193"
     CDS             85908..86906
                     /gene="ruvB"
                     /locus_tag="ACL3JB_000193"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0685007.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            86887..87459
                     /locus_tag="ACL3JB_000194"
     CDS             86887..87459
                     /locus_tag="ACL3JB_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGR0685008.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            87690..88448
                     /locus_tag="ACL3JB_000195"
     CDS             87690..88448
                     /locus_tag="ACL3JB_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0685009.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKYLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEVALQEAILAYNRRHRRFGGV"
     gene            88457..89260
                     /locus_tag="ACL3JB_000196"
     CDS             88457..89260
                     /locus_tag="ACL3JB_000196"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0685010.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            89282..90541
                     /gene="rseP"
                     /locus_tag="ACL3JB_000197"
     CDS             89282..90541
                     /gene="rseP"
                     /locus_tag="ACL3JB_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0685011.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            90554..92407
                     /locus_tag="ACL3JB_000198"
     CDS             90554..92407
                     /locus_tag="ACL3JB_000198"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0685012.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
BASE COUNT        28195 a        16510 c        20050 g        27699 t
ORIGIN      
        1 tcagttctat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
       61 tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat gaaagaaaaa
      121 ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt cagtatcgac
      181 ctggcctgtg ggactatcgg tgcgccctat gtgacacctg ttgagatggg cttgatgagt
      241 ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt ggttcaagct
      301 cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt tttgttgagt
      361 ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg tatgtctagt
      421 atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac agacaaggta
      481 aatcctatgt ggatgcacgg aaacaatctt aacagctatg tggcttggtt tgtggggaca
      541 gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgg cttggatttt
      601 gccctggttg ggatgtttat tggtattttt gcttcgcaat ttcagattat gcaaagacgg
      661 attcctgtcc gcaatctgct cattatccta gcagttgttg cggtgtcctt ctttttgctc
      721 ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga cgctacttgg ttgtagcatg
      781 ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct ctggcttggt
      841 gacttggatt ctccgtatga ttcccttcat cttagtcaag tataagggct tgcctgcaat
      901 cgttgagcgt tttttgaagt tcttgcccgt ttccattatc tttgccttga ttctttcaag
      961 cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa tggctagact tcttagccgt
     1021 ctttccaaca gcttgggtag cctttcgcta ccgcaatcta gtcggaacag ttctctttgg
     1081 agtggtcttg attgccatct tgcgtttggt cttttaaatt acccataaaa aaaacttatc
     1141 acagagatag atatcatata atggcgtaaa tgctcttttt ctgttaagat tataaggtat
     1201 tctattttgg aggaaatgac atgaaaaaaa tcgttaaata ctcatctctt gctgccctag
     1261 gacttgttgc tgcaggtgtg cttgcggctt gctcaggggg tgctaagaaa gaaggagaag
     1321 cagctagcaa gaaagaaatc atcgttgcaa ccaatggatc accaaggcca tttatctatg
     1381 aagaaaatgg cgaattgact ggttacgaga ttgaagtcgt tcgcgctatc tttaaagatt
     1441 ctgacaaata tgatgtcaag tttgaaaaga cagaatggtc aggtgtcttt gctggtcttg
     1501 acgctgaccg ttacaatatg gctgtcaaca atcttagcta cactaaagaa cgtgcggaga
     1561 aatacctcta tgccgcacca attgcccaaa atcctaatgt ccttgtcgtg aagaaagatg
     1621 actctagtat caagtctctc gatgatatcg gtggaaaatc gacggaagtc gttcaagcca
     1681 ctacatcagc taagcagtta gaagcataca acgctgaaca cacggacaac ccaactatcc
     1741 ttaactatac taaggcagat ttccaacaaa tcatggtacg tttgagcgat ggacaatttg
     1801 actataagat ttttgataaa ataggtgttg aaacagttat caagaaccaa ggtttggaca
     1861 acttgaaagt tatcgaactt ccaagcgacc aacaaccgta cgtttaccca cttcttgctc
     1921 aaggtcaaga tgagttgaaa tcatttgtag acaaacgcat taaagaactc tacaaagacg
     1981 gaacgcttga aaaattgtct aaacaattct tcggagatac ttatctacca gcagaggctg
     2041 atattaaata atttcttgaa atcatccatt ctgagtaaga tgggtgattt ctcagttttt
     2101 agggatatag ttttaaacta tatatctgat tatctaataa caatttgtga aatcaaacaa
     2161 attgtgagat actagtacgg tattattttt aaggagaaag aatcatgaaa atcaaaaaat
     2221 ggcttggcct agtagccctt gctacagtcg caggtttggc tcttgcagct tgcggaaact
     2281 cagaaaagaa agcagacaat gcaataacta tcaaaatcgc aactgttaac cgtagcggtt
     2341 ctgaagaaaa acgttgggac aaaatccaag aattggttaa aaaagacgga attaccttgg
     2401 aatttacaga gttcacagac tactcacaac caaacaaagc aactgctgat ggcgaagtag
     2461 atttgaacgc tttccaacac tataacttct tgaacaactg gaacaaagaa aacggaaaag
     2521 accttgtagc gattgcagat acttacatct ctccaatccg cctttactca ggtttgaatg
     2581 gaagtgccaa caagtacact aaagtagaag acatcccagc aaacggagaa atcgctgtac
     2641 cgaatgacgc tacaaacgaa agccgtgcgc tttacttgct tcaatcagct ggcttgatta
     2701 aattggatgt ttctggaact gctcttgcaa cagttgccaa catcaaagaa aatccaaaga
     2761 acttgaaaat cactgaattg gacgctagcc aaacagctcg ttcattgtca tcagttgacg
     2821 ctgccgttgt aaacaatacc ttcgttacag aagcaaaatt ggactacaag aaagcacttt
     2881 tcaaagaaca agctgatgaa aactcaaaac aatggtacaa catcattgtt gcgaaaaaag
     2941 attgggaaac atcacctaag gctgatgcta tcaagaaagt aatcgcagct taccacacag
     3001 atgacgtgaa aaaagttatc gaagaatcat cagacggttt ggatcaacca gtttggtaat
     3061 aagaaacagg gaggtgggag agagaattcc acctcttgct tttgtataga gcacggagtg
     3121 taaagaagac tattcgttca tagaaaggta gagagaatat ggtttttcct agcgaacaag
     3181 aacagattga aaaatttgaa aaggatcatg tagcccagca ttattttgag gttttgcgta
     3241 ccttgatttc taagaaatca gtctttgccc agcaggttgg actcaaggaa gtcgcaaatt
     3301 atctgggtga gattttcaag cgtgttggag ctgaagtgga gattgatgag agctatacag
     3361 cgccctttgt catggcacat ttcaagagtt cgcgtccaga tgccaagacc ttgattttct
     3421 ataaccacta tgacactgtg ccagcggatg gggatcaggt ctggacagag gatcctttta
     3481 cgctttcggt ccgcaatggc ttcatgtatg ggcgtggagt tgatgacgac aagggtcata
     3541 tcacagctcg cttgagtgct ttgagaaaat atatgcagca ccatgatgat ttacctgtca
     3601 atatcagctt tatcatggag ggagcggagg aatcggcttc aacagaccta gataagtatt
     3661 tggaaaagca tgcagacaaa ctccgtgggg cggatttgtt ggtctgggaa caagggacca
     3721 aaaatgcctt ggaacagctg gaaatttctg gtggcaataa ggggattgtg acctttgatg
     3781 ccaaggtaaa aagcgctgat gtggatatcc actcgagtta tggtggtgtt gtggaatcag
     3841 ctccttggta tctcctccaa gccttacagt ctcttcgtgc tgcggatggc cgtatcttgg
     3901 ttgaaggctt gtacgaagaa gtacaagagc ccaatgaacg agaaatggcc ttgctagaaa
     3961 cttatggtca acgaaaccca gaggaagtta gtcggattta tggattggag ttgcctctct
     4021 tacaggagga gcggatggcc tttctaaaac gtttcttttt cgagccagcg cttaatatcg
     4081 aaggaatcca gtctggttat caaggtcagg gtgttaagac tattttacct gcagaagcca
     4141 gtgccaagct agaggttcgt ctggttccgg gcctagaacc gcatgatgtt ctggaaaaaa
     4201 ttcggaaaca gctagacaaa aatggctttg ataaggtaga attatactat accttgggag
     4261 agatgagcta tcgaagcgat atgagcgcac cagccattct caatgtgatc gagttggcca
     4321 agaaattcta tccacagggc gtttcagtct tgccgacgac agcggggaca ggacctatgc
     4381 atacggtctt tgatgcccta gaggtaccaa tggttgcatt cggtctagga aatgccaata
     4441 gccgagacca cggtggagat gaaaatgtgc gaatcgctga ttattacacc catatcgaat
     4501 tagtagagga gctgattaga agctatgagt agagatatta tcaagttaga tcagatcgat
     4561 gtgacttttc accaaaagaa gagaaccatt acagcggtta aggatgtgac cattcacatc
     4621 caagaagggg atatctacgg aatcgttgga tattctggag cagggaaatc aacccttgta
     4681 cgggtgatta acctcttgca aaaaccatct gcagggaaaa ttaccattga cgacgatgtg
     4741 atttttgacg gcaaggtgac cttgacggca gagcagttgc gtcgtaaacg tcaagatatc
     4801 ggaatgattt tccagcattt taacctgatg agccaaaaga cagcagagga gaatgtagcc
     4861 tttgccctta aacactctga actcagcaag gaagaaaaga aggctaaagt agctaagttg
     4921 ttggacttgg ttggtttggc agatcgtgct gaaaactacc cttcacaact atctggaggg
     4981 caaaaacagc gtgtggcaat tgcgcgtgcc ttggccaatg atccaaaaat cttgatttca
     5041 gacgagtcaa cttctgccct tgatccgaag acaaccaagc agattttggc cttgttgcaa
     5101 gatttgaacc aaaaattagg cttgactgtt gtcttgatta cgcatgaaat gcagattgtc
     5161 aaagacattg ccaaccgtgt tgcagttatg caggatgggc atttgattga agagggtagt
     5221 gtgcttgaaa tcttctcaaa ccctaaacaa cctttgactc aagactttat ctcaacagct
     5281 acaggtattg acgaagccat ggtcaaaatc gagaagcaag aaatcgtgga acacttgtct
     5341 gaaaacagtc tcttggtgca actcaagtac gctggagctt caacagacga gccacttttg
     5401 aatgaattgt acaagcatta ccaagtaatg gctaatattc tctatgggaa tatcgaaatt
     5461 ctcgatggta ctcctgttgg agaattggtg gtggttttgt caggtgaaaa agcagcgttg
     5521 gcaggtgccc aagaagccat tcgtcaagca ggtgtacaac taaaagtatt gaagggagta
     5581 cagtaagatg gaatcattga ttcaaaccta tttaccaaat gtctataaga tgggttgggc
     5641 tggtcaggca ggctggggaa cggctatcta cttaactctt tatatgacag ttctttcctt
     5701 cattatcgga ggcttcttgg ggctagtggc aggtctcttt ctcgtcttga cagcgccagg
     5761 tggtgtcttg gagaataaag tcgtattctg gattttagac aaaattacct caatttttcg
     5821 tgcggttccc tttatcatcc tcttggcaat cttgtcacca ctttctcact tgattgttaa
     5881 aacaagtatc gggccaaatg cagcccttgt cccactttct tttgcagtct ttgccttctt
     5941 tgcccgtcag gtgcaggttg tcttggctga attggatggc ggtgtcattg aggcggctca
     6001 agcgagcgga gcgactttct gggacatcgt gggtgtttac ctatcagaag gtcttccaga
     6061 tttgatccgt gtgacgactg tgaccttgat ttcccttgtt ggggaaacag ctatggccgg
     6121 tgcggttgga gctggtggta tcggtaacgt agccatcgct tatggattta accgctacaa
     6181 tcacgatgtg accatcttgg caaccatcat tatcattttg attatctttg caatccaatt
     6241 cttgggagat ttcttgacta agaaattgag ccataaataa aaaagagccg tgtggctctt
     6301 tttaactgat cagattttct gggcaaattt tttactcaag gcttgtccaa tcaaggcacc
     6361 cactagggct ccgatgacaa tacttgcgat aaatagaagg acagttccag ggtttggagt
     6421 gaccatgata cggtcgatat attcttggga ttttcctctt gccagaagag tagccatata
     6481 ggctttgggc gcaatccaca taagcaagat tggtcctgtt gtactaaagg cgaaaataat
     6541 gaaagaaagg aagttctttg ttttgtcctt gtattttcct aaatgagcta cttcatctgc
     6601 taggaggcca cagataattc caggaaggaa ggaaccagca ccgtgtttag ttcccaagaa
     6661 aaagaaggca atgacaaggc cgatagtggt aatggctcca aagcgcggaa cttttgcgac
     6721 taggatcata tagacgctac cgccgacaag ggcagtaaag gcaggcgcat aaaacatgtt
     6781 tccagtttgg tcaaagagat tgcccaaaag gacaccaatc cccatgcaga ggaagtaaag
     6841 aactgcaaaa agcagtgtag ttaagataga ttttttcatg aattgtctcc tgataatttt
     6901 ttcacaattc tcattgtacc acggtttggt gggattgtaa atggatacta gaagtttttg
     6961 aaaacgcttg aaatatgata taatggtttc atagttattt ttaggggaat atcatgggta
     7021 gatttttaga ctttgtcttt aatcgtttct ttttagggat gattgcgaca gccttctttt
     7081 ggctattaac tttagcagga gggattatcc ttggtctagc gccggctagt gccaccttga
     7141 tgagcttata tgcagaacat ggttatagct ttcgggaata cagtttgaag gaggcttggt
     7201 ctctttacaa gcaaaatttt gtctcaagca acctgatttt ctatagcttt ttaggtgtgg
     7261 gtctagtttt gacctatggt ttgtatctct tggtgcaatt gcctcatcag accattgttc
     7321 atttgattgc gacccttttg aatgtcctag tagttgccct gatctttttg gcttatacag
     7381 tatctttaaa attacaagtt tattttgcct tgtcctatcg aaatagtctc aaattatcct
     7441 tgattggcat ctttatgagt ctagcagctg tggccaaggt tctccttggg actgtgctac
     7501 ttgtagcaat tggttactat atgcctgccc tgctattttt tgtaggaatt gggatgtggc
     7561 atttctttat cagtgatatg ttggaacctg tctatgaaat catccatgaa aaattggcga
     7621 caaaatagaa tgaagcagtt ttggctacat acgcttctaa gaacctatag ttcagtgatg
     7681 atcattatca ttgcgagttt tgcaatctta ctctcttacg ctgactggga ttcacgtgaa
     7741 aaggaagccc agagagtagc ccagcgtgta actgctagaa cagtgagtga aattgaatat
     7801 taccatagag agtcaaccca gatagctcag gctttagttg aaaaccaagc tcgtattgag
     7861 ggaatctata aatactttag ccttagcatg ccagactatt tttactggca attagagcgg
     7921 aaagcttcgc cttatatatc agtctctctg tatgaaaatg ttgatgacct ctatgttcga
     7981 aatgattttg taactggggt ggccattgct tttcaagatt acaaggaagt ctatgtttct
     8041 actaaagaca aacgtagtgg agaaaaaatc agggctgagg atttcaaacc agcaggaaat
     8101 agttttgcca ttccagtgtc agatccagtg tcagatcaag acttaggagt gatttacatc
     8161 tccttggatc ctgctgtttt ataccatgcc attgataata ctagaggtca tactccgatg
     8221 gcagtaacag tgacctcacc ttttgatacg gagatttttc atatgggtga gacagttgat
     8281 aaggagagtg aaaattggct agttggctta acttctcatg gttatcaggt tcaggtggca
     8341 gttcccaaaa actttgtttt acaaggaacg gtgaccagct ctgctttgat tgtgggcttg
     8401 agccttctct ttattgtcat tctttatctg actttgaggc agacctttgc taattatcaa
     8461 aagcaggtag tggatttggt ggattccatc caagctattg cccaaggaca agaaggtctt
     8521 cgcattgata cgcttgaaaa ggatcaggaa ttgctcctaa tcgcggagac gaccaatgat
     8581 atgttggatc gattggaaaa gaatatccat gatatttacc agttagaact cagtcaaaaa
     8641 gatgccaata tgcgggcctt gcaggcgcaa atcaaccctc acttcatgta taatacgctg
     8701 gagttcttgc gtatgtacgc agtcatgcag agtcaagatg agttggcaga tatcatttat
     8761 gaattcagta gtctcttgcg taacaatatt tccgacgaaa gagagaccct cctcaaacag
     8821 gaattagaat tttgccgtaa atacagctat ctctgcatgg ttcgctatcc caagtccatt
     8881 gcctatggtt tcaagataga tccagagtta gagaatatga agattcccaa gtttaccttg
     8941 caaccgctgg tagaaaacta tttcgcgcat ggtgttgacc acaggcggac agataatgtg
     9001 attagcatca aggctcttaa acaggatggg tttgtggaaa ttttggtggt cgataatggt
     9061 agaggaatgt cggctgaaaa gttggcaaat atccgagaaa aattaagtca gaaatatttt
     9121 gaacaccaag ccagctacag tgatcaaagg cagtctatcg ggattgtcaa tgtacacgag
     9181 cgttttgtgc tctattttgg agaccgctat gccattacta tagagtctgc agagcaagcc
     9241 ggtgttcagt atcgtattac aattcaagat gagtagaaag ggagaaaatg tataaagtat
     9301 tattagtaga tgatgagtac atggtgacag aaggtctgaa gcgtttgatt ccctttgata
     9361 agtgggatat ggaggtcgtc gcaacagcca gtcatgccga tgaagctcta gaatatgttc
     9421 aggaaaatcc tgtcgatgtc atcatttccg atgtcaatat gccagacaaa acagggcttg
     9481 atatgattcg ggagatgaaa gagatcttac cagatgctgc ctatatcctg ctctcaggtt
     9541 atcaggagtt tgattatgta aaaagagcaa tgaaccttag tgtggtggac tatttggtca
     9601 agcctgttga taaggtagag ctgggaaatc tgctggagaa gattgcaggt cagctcggcg
     9661 agagagggaa gaaaagtcag actcttagtc aagaattaga cgaggctgga tttgttagtt
     9721 atttagggga taaggagaat tggtggatag gtctatccaa ggaaaaacaa ggttccttca
     9781 ccattcccta ctatgtcttg ggccaagact ggcagatttt catttctgac caacccctag
     9841 atggtttagt cgttacacct tttgaagctc cttatcaaga acactttgaa cgctggaagc
     9901 tgaatgctga gaaaaccctc ttttacggtt ctgtaaattt gcagcagtct gagagtctct
     9961 ttgcctatta cgaaccgatt tatagggtta tcattcaggg aaatctcaat caaatcgtag
    10021 aagagttaaa tctcttggag aaggtagttc ttgaaaatac gccgcgtgtt ccgattacta
    10081 aacagctttt tattcagttt gtcatggatg ttttccattt atttgaacat ctcaaagctg
    10141 atgacctgac agacatcgtc aaaaccattc atgctattca atccttcgat gaattggttc
    10201 cttatatcaa ggaaactctg agcagctttt tcggtcaata ccgtatgaat gaaaatgtgg
    10261 tcagtgtgct ggaagtcatt ggtcgtgatt accaaaaaga gctttccctc aaggatatca
    10321 gtaaggctct ctttatcaat cctgtctatc tagggcagtt gattaagcgt gaaaccgatt
    10381 cgacttttgc agagttacta aacaaacaac gtattaaggc tgcccaacaa cttttgcttt
    10441 caactagtga cagcatcgaa gatatttgtt atgctgttgg ttacagtaac cttggatatt
    10501 tctataaagt tttccgaaaa ttgtgcggaa aatcgccaaa agcctaccga aaacaggtag
    10561 aaactatact ataagatttg tattccttta caaaaggtgc tataatatta tcaggaggtc
    10621 ctatcatgaa aaagaaacca atttatctat gggtcttgct aatcttgtct gcccttattt
    10681 cagttccgtc tctgtttgga attgtgagtc ccttgcctag taaagaagcc cttcgtgctg
    10741 ctcagaaaca agttgcaggg gtcaatgctc agcaattaga agaccagctt aattatacct
    10801 atagagtagc agaagcatct cattctattt ttaatgttgc tttgattgtg ctatctacta
    10861 ttttagtggt cgtagcgatt gtcttccttg ttcgtaaaaa tttgcaatat gcaaactata
    10921 cttacgttgg ctatgttttg ttagctatta ttggttcgat ttatggctat gttggtttac
    10981 aagacgctgt gcagttggtt caagatgaga gcatgcgttt gacagtgagt attggctcaa
    11041 aagctgttag cattttctat atcgtcatca atgttctctt cctagccctt gtcttctata
    11101 agatgtggcg acaacagaaa gccttggcag aagaagagga aacagaagag cttacctaag
    11161 tattgacaaa aaagaactat caagatacaa tcttggtagt tgttttttga ttatagataa
    11221 aatcatggag gtacatatga agacaatttc tttagtttat attagtttga gtggcaacac
    11281 tgaaagtttt gtgacgcgct tgaaagacta tctcttgtcc cagtacaaag ggattgaggt
    11341 tcaaaagatt catatcaagg atttggtcaa ggaaggcaaa aatttctatg aaatggacca
    11401 tccctatgtc gcttttttgc cgacctatct cgaaggtggg aatggcgtgg ataacggaga
    11461 tgttgagatt ttgacgacac cggtgggaga ttttattgcc tatggtaaca atgctagtaa
    11521 gtgttttggt gtggttgggt caggaaatcg taactttaat aaccaatact gcctaacagc
    11581 caagcaatac agtcaacgct ttggcttccc tgtattggct gactttgaaa tgcgaggcat
    11641 gctggaagat atcaaacatg tcgcagctat tatcgcagat ttgtatgagt tggaaaagga
    11701 gaattaatac tcaatgaaaa tcaaagagca aactaggaag ctagtcgcag gttgctcaaa
    11761 gcacagcttt gaggttgcag atagagctga cgtggtttga agagattctc gaatagtata
    11821 aagttcttat aagaggtggt tgaagttgtt caactgtttt ttgagtataa acagtcttta
    11881 agaacgtaaa aaagcataag ttcaggtctt caaaaccttg ttcttatgct ttttatcata
    11941 gaaatatttg ctgaattttc tcttgaaatg aaaccttatc ttcatctcgc gcttgtccct
    12001 taccctgctt ttccgattgc gagtgcgtag ataaagaaga tggcgaagcc aaagaggaaa
    12061 atcaatcccg caatggcaag gtgtttgagc caagaaggaa gatttttgtt ttcacgcgtt
    12121 accaaggcgt aattcaaaag agcaaagaaa ggtgttgtca ggaaagatcc aatcatggca
    12181 aagcggagca tggttgaaac ctgaccagcg aagaacttga taatgacgat accgatgata
    12241 gcagtgatgg tcatccagat gttcaaagat ttacgattgt cctctttttg actgattagc
    12301 agtcggagag attcctgatt aacgcgagaa tagccatcga taacagttat aactgttcca
    12361 aagatacaga ggaaggcaat aaaggtaatc aagtaacggg accattcgcc aagaacagag
    12421 gcatacatgc ccacgaattg agagatgtat ttggctgaag cagcttcaac cgcctgccct
    12481 gtaggatact gaatcagtgc tcccagtgcc acaaagaaga cggctaggat agctgttcca
    12541 atataaccag tgttaaagtc aaacagagcg tcttctgtgt taaagttgac ggtctttctc
    12601 ttttcagctg accaaagtga attgatggct gaaatttcaa taggagccgg catccatcct
    12661 aggagggaga cgatgaaggg cagagctgcc atttgccaag gtgtcttctc gacaaaatca
    12721 gaactgtatt ctggatgctt gaccgccgca atgataactg caagaacagt cgcaatggtt
    12781 aaggcagaca taatccattt gaccatgccg tctaaaagtt tgtagcctcc aaagagtagc
    12841 atagcccaaa tgattgcaac gagaatgagg gaccactgag taatgctaag tccaatcatt
    12901 gggaaggcac tggcgatgat agctgagcac agaatggcaa caccagccgt gttgaccata
    12961 gccgaaaaga cattgagaat aaagaaaatc cagagataga gttttccttt ttcggcataa
    13021 ccttcaacca aagtctttcc agtatcagct gtgtattcag caccaaaacg gaaaaatgga
    13081 tatttaaaga cattggctaa gatgaccaag agaagtagag accaaccgta agaaccgcca
    13141 gcttgagttg aggatacaat gtgggaacct ccaacagcgg cagttgccat taggattcca
    13201 ggtcccattg cttttagctt gcttgcccag gttgattgat ttaaggaaat agcttgcgac
    13261 atgataaata ctcctttttg aattttcaga ataatctgta tatgcaatct atattctaca
    13321 aaaaattttg gaaaaatgca agaatatttt gaaaaaagat agaaaattta caaagaaaat
    13381 ctgaaataac tgttatgata tagcagattg aaactagaat agtacacctt tgcttctaaa
    13441 acattgttag aaatcgattt gactgtcctg atcgatttat cctgttctta tttcatttca
    13501 ctatagtaag gtgcagcagg ataaagaaaa accgagaagt ttctttctcg gatttgctta
    13561 ttatgaggtt cctattttct atgctccaag agttgattga tgtgatctac ttttttagcc
    13621 tctcttttat agagaatagc ccagatgatg agatagacaa tcgcaaactc gataatgagc
    13681 tggaggtaga aaatccagtg gaaggggaac caaccagcaa gagttgctag tgggacaaag
    13741 ccagccagca taaggaagaa atgagtcaga gtggcacgaa gcatgctcca gtcacggctg
    13801 aataagcggt tgccaaagtt gaagagcata ccgatggctg cccagataag tgtgcagtag
    13861 agcaagacca gggcaccgtg aacctgatgc tgatccatca cttggccgat gagagagtag
    13921 ggatttagtg gtgcgtaggt atttggtgca taaatgagtg aaaagaggat ggagaggatg
    13981 aggccgataa gaacaccggc agctgcatcg tgaaatactt gttttttcat agttctaatt
    14041 tctccttgat ggtttttaga taacggcgtg aagagtaggt gaagctttcg tttttcaaga
    14101 aaatttctac cagaccgttt ggcgtgagct tgaggtgaga gatggaatcg atattgatga
    14161 tttctgattg ggaaatttgg ataaaattgg ttggcaagag tttaagaacc tgatagagtc
    14221 gcaaatcaat gctgtaggtc tgactcgcgg tttctgctag aaccttccga ttctcgatat
    14281 agaagcgctg aatcttgcca atctcaacta gatagacctg atcatcgatt ttccctttga
    14341 ttttttctct ttggtccaga ttttctgcga actcgatgac tttctgaact ttatctgtcg
    14401 gctgaggtgc ttggacaatc agcttttcct cctcgtaagt ctcactaatc tgtaattcta
    14461 ctttcataaa tttctctcct tgtttttcat acaaaattaa tctcacttct tgtacacctt
    14521 tattaatact cttcaaaaat ctcttcaaac cacgtcagcg tcgtcttgcc gtaggatagt
    14581 tgttgacttt gtcagtttta tctacaacct caaaacagtg ttttgagctg tctgcgccta
    14641 gctttctagt ttgctctttg atttttattg agtataccac tattttactc cctctggcaa
    14701 ggtactttgt ctatgtggag ggattgggct cctatgtggt ggagcttttc tgttctttct
    14761 gaaatatggt ataatagcac taatcaattt ctaggaaaat agatacagaa aggggctgaa
    14821 agaactaggg gaacagttgt aattagaagg tgataggtat gaaaagtggc gttgaagctg
    14881 gataagttta taaagagttt gaatgaagaa atgaaaagta aataagttga tgatgaattg
    14941 caaaaataga ttttatatac aatttgtatc tttcgaatca ttgatttgaa ttttagattt
    15001 aatcatgtta caattaaaac tgaaatcaaa tagaagagga aaatgcaaac gtgggcacac
    15061 tattagcaac aagattaaaa aatagacgga aagaattaaa aatgtctcag cgagaactag
    15121 ctgaaggtat ctgtaaacag gggcaaatca gtcgattaga gagcggagag tttacccctg
    15181 gagcggattt cctgcatgcc cttgctaaga agttaaaagt cagtatggat tatttttttg
    15241 atgagcaggt tgtagagaaa gttgaggagt tatcggaatt taagaaatta gcacagacat
    15301 ttattacaaa tcgcaattat gagtctttga aatatatata tgaattggag aatgtaaaag
    15361 ctcaccgcct atctttagca gataaaatct acatggaatg gataaaatct ctgatagatt
    15421 tttattttta cggacagaaa gaagatgcga ttgtacgatt agagggggta ttatcacagt
    15481 taagtgtatc tgatttgaac tatctccaag tttcaaacac cctattcaat ttttactatg
    15541 atattggaga tttaggtcgt ttcaataaaa ttcgtgaaaa actagagtat cgagtaaatc
    15601 aactcaattt gagtacaatc gaagagttag agctatctat taagtttaac tacaacgttt
    15661 gtcgttatct atggttacag aaaaatattg aagaagctat tactaaaatt acagctacta
    15721 taaaacaatg taaggcatac agaacgaatt atcttttggc tgatttgtac ttattgatgg
    15781 gaaacgtaag tgaaaatttc tcttctaaaa gttcagtgaa agaatatttt gagacagctc
    15841 atttccttta caaattagag gaaaacatgt caatggcttt gaaagttgag cattacattg
    15901 cagatataac agaataatga atacggtgtt caagtgagca tcgtttttca aacccagttt
    15961 agatacaaaa aagtatcaaa caaaaaaaaa taaaaaaaca ttataaaaat acttgacaag
    16021 ctaattttga agtgataaaa taaatgcaag aaaaaaggag aggtatatga gaagtttatt
    16081 taagaaaata gttgctgtat tagttattgg attaattctg ttagggattg cgagaacacc
    16141 ccaagttcat aagatagcta gagggattga tccaggtcca gcgaatgggc aagctctcta
    16201 actgttcaga ctaatctata acgacattat gaggtttgat aagatttctc ctcaccagat
    16261 aaaaatctta aattttataa tagagggaga aattaaattg aagtttaaga agaagagctt
    16321 aaagcctaag aaaattcgtt ttgtactagg ttacaatggc ggtgataaat aagtacaagt
    16381 atgtatttgt ttttattaag aatctaagat taaatcttag attcttaatt ttttattaga
    16441 ttttataata tttattctaa aaataataga caagtataat ttatattata tgatatactc
    16501 atctgattta cttttaagct acttagttga aaacgaaaaa ttgatcagaa ttcgttagat
    16561 ttcagtaaat ctggataatt attgtatcga gtatgaatat tttgaaaaaa agaagaattt
    16621 tatgtatttg gagaagaaaa tgcaaatatt aatttctgaa gtaaatgtaa ctagttttgg
    16681 aattacaaga gaaattttaa agaaaatgga ttttaatttc tcaaaaatgg gtagcgaaga
    16741 agctaaattt ttaatttttc cagagttacc tagaggaggt gagctaagtt taactgctcg
    16801 tcaaagttat gatagccagt taaggtattc gatgttacct agagttgagg acatcatgaa
    16861 gaaaattgta aatcaactta gagaacattt aaaaatttta gacattgagc taagtgattt
    16921 aagttattta tcagagggtg atcaattcat attaaaggaa ctatcaagtc atgtaaaaat
    16981 aaatattaaa attactccaa taaaaaaaat acgttatgta tatgaagata tctttctcaa
    17041 tcaatcagca gaggaattac atgaattagg attaaaatat ttatcagcag gtgatttatg
    17101 ggcttctaaa aaaatattta cttacttagt aaataaatat gataatagac gagatgtttt
    17161 caaattagct acaacttata atatgttatt ggaaacagaa aaagcagaat actactacaa
    17221 cctatacaaa catgatggaa aagttgacca tattgtggca gcaaactata tgcttgcaat
    17281 gctctatgca cgccatcatc ctaaatacct tcaagatgat caaaaagcta ttgtattatt
    17341 gaatgaagcg tatgatttaa ttaaagataa agtgacatta gagagtattt ttaatcgaaa
    17401 tgggtatgcc ctactattat ttaaaatggg caaagtagag gaaacaatca tattattaaa
    17461 acgttgttta aatcaaataa aacaattaga taactctagt tcttcggttg ttcttcatga
    17521 aagtgtactt tggtttaatt tatatcagtg ctatgtcact ataggtgaca atactaattc
    17581 tcggaaaact ttttatattt tgaaaaatat ggatccgctt tttattgagt actatctaga
    17641 atattctaga aatcttttag agacagatgt cgaaaatttt ctagaattta tagagagtat
    17701 gccacatcat tctaataatt ttgctgaaaa atattcgctc ctaggctact attttagagg
    17761 tactgcgaaa tcattagaat attttagtaa agcttttgaa ttgtcaaata gaacgttttc
    17821 tttttggtac gatataactt atgaactaac ggagtttaat ctttacaatg aagcatacaa
    17881 taatttacct ttattgaata ataaattgta tgagctgaat gatgaagact tactaaatta
    17941 tattttaatt tcggcagaaa ttttttataa tttagacagg ttggatgaat ttaaacgaac
    18001 tatagaaatt gggtatagaa tttttcctga ttcagaaagt attaaagaaa ttatagagaa
    18061 tgccgaatga aaagatataa aactctattt ataaagtatc ctgattcttt ccagttttta
    18121 gtttttaata ttctgtttta tttatcaatg tcactttcta ggagtgttca ttcaatttgg
    18181 tttgatttga atggaagttt actgaattat agtatttcat attcagcaat ggctttttca
    18241 ggaatgtttg ctggaattct aggcagaaga attaattatt ttaatttaag aaatctgata
    18301 agaataggag taatactata ttctatcggt ttattattga gattatttcc taatgattgg
    18361 ttgatatcat taatctctgg tcttatctca ggtattggag cggcaacaat aattctttta
    18421 ttgcgaacat gggctgtcgg aataggaaaa gaaaaagaca gagtagttac gatttcctta
    18481 aaaagatttt ccagcagttt aggaacttct attggaggga tattgtcagg cattttgcta
    18541 tattgcttaa tatatttttt tcatagtatg gcgtatccta ttgttttagc ttcggcaagt
    18601 atgctatgtt tagtaacttt cttttgtatt cctaaaattg acagttttgt tgataagagt
    18661 gaaagagcag aaagaatctt agaatctagt aattacatga aaaagagaat aatctttttt
    18721 ggtatcttct caggtttaat tgctagtata ttttctcctt atctacccgt tattttaaga
    18781 cgtcaagaaa tatcagaagt ttttattggg cctgttctaa ctattttaag tctattaaca
    18841 atttatttct cttccatatt ttcaagtaga aaagtagata atcataaaca aggatattat
    18901 attttatccg agttgttgat ttcgatactt actttattat ttagttttca tttaaaatat
    18961 tatttagtaa taacgatatt gattattaga gtattttttg taaacctatc atcaattaca
    19021 caagagttaa tggaattatc aatttatcca aaggaaaaaa tttcatattt ctatggcatt
    19081 tctcaaactt cctattttat aggtgatact ctgggaggat ttattggagg ttggctattt
    19141 aaccaagata tgaaatacag tatttatctg ttttctgtgt tattattatt caacgctgtg
    19201 ttatttaaca gattttactt acggaataat aaaaattctt aagggacctc taaaaaaaac
    19261 agaagattaa aatacagtaa aaaaatcaac taaaatagtc ccaaagtaaa gaaatacttg
    19321 aacctatttt agctggtttt cttttttttc acctctaatt gaggattatt ctattttagg
    19381 gtatactccc ccatgttttc aaccctaatc gttggatttg ttcgaaacga cagatattat
    19441 acaacaaatt tgtcaaaatc acattcgttt ttgtacgcgc taatccaatt cctctaaaat
    19501 gacttccttt catcgtattt ttaataacac caaaaacatg ttccacacga cagcggatac
    19561 gagaaataga ctgattgata cgcttatcca aatcagtcaa ggttttattt cgaaaagcac
    19621 tatcatcaaa gatcggctcc ttactctcac acaactcttc caagacgcga gaatcgtgaa
    19681 tattagcaga agtaatctca aatttcttga ttagttttga tttttggtcg atactaatac
    19741 tcaatgaaaa tcaaagagca aactaggaag ctagacgcaa gttgctcaaa acactgtttt
    19801 gaggttgcag atagagctga cgtggtttta atttgatttt cgaagagtat aatatgattt
    19861 gtataaccaa agtaagttgg ttctccctag tccatcctgt atccctatct ttttgagaag
    19921 gcttcgctgt attccaatct gtcggaatct ttcctttttt gatttgttga ttctcttctc
    19981 gtgtattgcg ttgtttaggg gattctacaa atggggcatc tactatctgt ccctgatgag
    20041 ctaataagcc tttttctgct agtgttagat aaaattactc agataattct tgttctttct
    20101 ctgatttggt caagcgttct ctatacaacc agatggtttt tgcatcatgt actttacatt
    20161 catcacaacc tgtggaatga cgaaatgaca gacgatgaaa gagttgatat tccatcgcat
    20221 catctgataa attatggaga tgttggatca agagcacctt aaatatcatg aaaaaatcat
    20281 gcggagggag tccgcctttt gatggtttct aaaaatctgc tcaagaatag gtctaatttg
    20341 ctcccaatcc attgccttat ctaagccttc caatggattg cccattgaac tcaattttga
    20401 tagtgtttgt tcatcatcta taaaaaattc catcgcctaa cctagcttac ctctatctct
    20461 agtatctcat gttttacgat ttttttgggt ttttagaggt gcccttaaat tcgttcatta
    20521 atgttacgag actggccgaa aattagtctc taaataaaac cacacagtga tttcagtctt
    20581 gaatccaatc aaactgaaag aagcactatg tggtttttga atagtgggct agattcttga
    20641 tcaatttggt gagattcatg gtaatcgccc aataacgagg tatattgaaa aatctacaga
    20701 ctagagaact cactgatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
    20761 actttagtcc atggtaaata agcctctaaa acatctttat ttacgagagt ctcctcgcct
    20821 agctttctag tttgttcttt aatttttatt gagtatacca ctattttact ccctctggca
    20881 agggactttg tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc
    20941 tgaaatatgg tataatagca ctaatcaatt tctaggaaaa tagatacaga aaggggctga
    21001 aagatgtctc atattattga attgccagag atgctggcaa accaaatcgc ggctggagag
    21061 gtcattgaac gtcctgccag tgtggtcaaa gagttggtag aaaatgccat tgacgcgggc
    21121 tctagtcaga ttatcattga gattgaggaa gctggtctca agaaggttca aatcacagat
    21181 aacggttatg gaatttccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt
    21241 aagataaaaa atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc
    21301 ttgccttcta ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt
    21361 catggaacca agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt
    21421 cctgtgggaa ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag
    21481 tatatgaaga gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc
    21541 ttggcccatc ctgagatttc tttcagcttg attagtgatg gtaaggaaat gacgcggaca
    21601 gctgggactg gtcaactgcg ccaagctatt gcagggattt acggtttggt cagtgccaag
    21661 aagatgattg aaattgaaaa ttctgaccta gatttcgaaa tttcaggttt tgtgtccttg
    21721 cctgagttga ctcgggctaa ccgcaattat atcagccttt tcatcaatgg tcgttatatc
    21781 aagaatttcc tactcaatcg tgctatttta gatggttacg gaagtaagct catggtaggc
    21841 cgttttccac tggcagtcat tcacatccat atcgacccct atctagcgga tgtcaatgtg
    21901 catccaacca agcaagaggt gcgaatttct aaggaaaaag aactgatgac gctggtctca
    21961 gaagctattg ccaacagtct caaggagcaa accttgatac cagatgcctt ggaaaatctt
    22021 gccaaatcga ccgtgcgcaa tcgtgagaag gtggagcaga ccattctccc actcaaagaa
    22081 aatacgctct actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat
    22141 tatcaggtag aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg
    22201 gaccgattga ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac
    22261 cagctagacc atccagagtt agatcttgct agcatcgata aggcttatga caaactggag
    22321 cgagaagaag catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat
    22381 ctctttgccc aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg
    22441 gtcaagtacg aggagtaccg tgaaagcatt ggcaatgttg accaaagcca gcagcaactc
    22501 ctagtgccct atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg
    22561 cctctcttag aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta
    22621 cgtgaacatc ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc
    22681 gacatgctcc ttttgaccaa ggaagtttct atcaagaaat accgagcaga gctggctatc
    22741 atgatgtctt gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga
    22801 caactcctct atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct
    22861 gttttggtgc attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat
    22921 cacaccagtc tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt
    22981 tcaaaatcaa aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat
    23041 catggaaata gttacttcat tttttcctaa ttcttttcga aactcttttt aaacgacgtc
    23101 agttttatca gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac
    23161 atcgaagttg tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca
    23221 gagtattaaa ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta
    23281 tgcgtctaat gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc
    23341 cttatttcct gctttagtac cagctcgttc tatggcttgt tcaattgtat ctgtcgttag
    23401 cacaccaaac ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac
    23461 ctcgctacat acataatcat aatgacttgt atttcctcta atgacagctc ccaagcagat
    23521 aattgcatca tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc
    23581 tcctggaacc caggctacct cgatatcttt ctcgtttaca ttctctcttt tgagattatc
    23641 tagtgctcca gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc
    23701 tattttaata ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat
    23761 atttaaaatg tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt
    23821 ggcttctatt tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc
    23881 aaccttgtca ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat
    23941 ttgtgctcca atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc
    24001 aagcgtatcc atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat
    24061 tcctcgtccc tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt
    24121 catagcttta tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt
    24181 taaacattcg gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat
    24241 aagagcaaga tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc
    24301 gtatctagta ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct
    24361 atattcttgt aattctttga tggtaattag tggaatgttg tgtttcttcg aaaactgaat
    24421 taaatcatct gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca
    24481 ctcttttagt ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc
    24541 tagaacacca cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga
    24601 gggtgttata tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat
    24661 acctgtggtc gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt
    24721 attgttttca accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat
    24781 acaaattaat cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg
    24841 tgcagaacaa attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag
    24901 tcgtcccttc tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt
    24961 atcctttctg ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag
    25021 agttatccat cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac
    25081 tcccgacttg tttactctta agaatggttt gttccaaggt atgagggata acagatactg
    25141 aaaagtttac tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc
    25201 ctttttcaac tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat
    25261 tatcatcttt ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt
    25321 gacccccaag tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt
    25381 ttaatagagt aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt
    25441 gatggttgaa atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat
    25501 ggatatccgt taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct
    25561 gtattctttc aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc
    25621 actttctatg agatagtcat ttcctatttg agaaaaagca taaggtttca atctaatagc
    25681 gtcatttggc aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat
    25741 ttttggtgca atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt
    25801 cattagactg cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat
    25861 taaactcgat aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg
    25921 attttgatat agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat
    25981 atcatttgct gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat
    26041 gatacggata ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat
    26101 aacagtattg actcccacca taattgcact aacatagtgt cgtaactgat gcacatgctt
    26161 tcttgcttct tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc
    26221 cattgacatt gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa
    26281 actttttatt aagttaagac actcattttc taaaattcca acagtaactt gaagattatt
    26341 ttcctcaagt atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat
    26401 gactactctt gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa
    26461 gtgacaacag ggttcaagtg ttacataaag cgtcgctccg acaggggatt ctctacagtt
    26521 tttaagagca tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat
    26581 gatgtgatta tcttttacaa taactgcgcc gaccatagga ttgggattga cgtaaccagc
    26641 ccctttttgt gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc
    26701 tccaaaaaaa atataccttg aataggggac tactcaaggc atacaaaaga aaacttatgc
    26761 gattaacaaa aatactctga aatgacaagt aatcatttca gagcacgcaa aaagcacaaa
    26821 tatactttta tcttctttca tccagactat actgtcggct ttggaatttc accaaatcat
    26881 gcctttcggc tcgtgggcta taccaccggt agggaattac accctgccct gaagatagtt
    26941 attcaattac agatgattat agtacttaat tttgaatatg tcaacagata aataccgatt
    27001 gtttttgata tactgtattt gtgataatcg attctcgctc ctcggataaa gaaaatatga
    27061 tatactagat aaacgaaata agagagaagg aatactatgt acgcatattt aaaaggaatc
    27121 attaccaaaa ttactgccaa atacattgtt cttgaaacca atggtattgg ttatatcctg
    27181 catgtggcca atccttatgc ctattcaggt caggttaatc aggaggctca gatttatgtg
    27241 catcaggttg tgcgtgagga cgcccatttg ctttatggat ttcgctcaga ggatgagaaa
    27301 aagctctttc ttagtctgat ttcggtctct gggattggtc ctgtatcagc tcttgctatt
    27361 atcgctgctg atgacaatgc tggcttggtt caagccattg aaaccaagaa catcacctac
    27421 ttgaccaagt tccctaaaat tggcaagaaa acagcccagc agatggtgct ggacttggaa
    27481 ggcaaggtag tagttgcagg agatggcctt cctgccaagg tcgcagtgca agcaagtgct
    27541 gaaaaccaag aattggaaga agctatggaa gccatgttgg ctctgggcta caaggcaaca
    27601 gagctcaaga aaatcaagaa attctttgaa ggaacgacag atacagctga gaactatatc
    27661 aagtcggccc ttaaaatgtt ggtcaaatag gagcagagaa tgacaaaacg ttgttcgtgg
    27721 gtcaagatga ccaacccgct ctacatcgcc tatcatgatg aggagtgggg tcagcccctc
    27781 catgatgacc aagcattgtt tgagttgttg tgtatggaaa cctatcaggc aggcctgtct
    27841 tgggaaacgg tactcaacaa acgccaagct ttccgagaag cctttcatag ctatcaaatt
    27901 cactcagtcg cagagatgac tgagactgaa ttggaagcca tgctggagaa tccagctatc
    27961 attcgaaata gagccaagct ttttgctaca cgcgctaacg cccaagcctt tctacagtta
    28021 caggcagagt acggctcttt tgatgcctat ctttggtctt ttgttgaggg gaaaactgtc
    28081 gttaacgatg ttcctgatta tcgccaagcc ccagctaaaa cacccttatc tgagaaatta
    28141 gccaaagatc tcaaaaaacg aggcttcaag ttcacaggcc cagtcgccgt attgtctttt
    28201 ctacaggctg cagggctagt tgatgaccac gagaatgatt gtgagtggag aggtcttaaa
    28261 tgatgtctaa caaaaataag ggaattctga tttttgcgat tctctataca gtcctcttta
    28321 tgtttgatgg cgttaaattg ctggcttctt taatgccatc tgccattgca aattatcttg
    28381 tttatgtagt tttagctcta tatggctcct tcttgttcaa ggatagattg atccaacaat
    28441 ggaaggagat tagaaagact aaaagaaaat tcttctttgg cgtcttaaca ggatggctct
    28501 ttctcattct gatgactgtt gtctttgaat ttgtatcaga gatgttgaag cagtttgtgg
    28561 gactagatgg acaaggtcta aatcagtcta atattcaaag tacctttcaa gaacaaccac
    28621 tactgatagc tgtttttgct tgtgtcattg gacctctggt agaagaatta tttttccgtc
    28681 aggtcttatt gcattacttg caggaacggt tgccaggttt actaagcatt attctggtag
    28741 gacttgtttt tgctttgact catatgcaca gtttggctct atcagagtgg attggtgcag
    28801 ttggttactt aggtggaggc cttgcctttt ctattattta tgtgaaagaa aaagagaata
    28861 tctactatcc cctacttgtt cacatgttaa gcaacagcct ctccttaatc attttagcta
    28921 tcagtatagt aaaatgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc
    28981 taacaatgtt ttagaagcag aggtgtacta ttctagtttc aatttactgt aatatgtgat
    29041 gaaaatgcca gtaatgatac cgagaaaaaa gctgagaaac ttttcccagc tttatttgtt
    29101 atagtcaaag cgaatgactt gttcctgtgc atctacatga gcatggaccc caaagggtac
    29161 aattgctctt ggagttgcgt ggccgacatt cagattatag acaatcggga tattgctgtc
    29221 aatgatatcc aatagtgcct ctttatagtc gtcatggaaa gtttcatcca taggttttcc
    29281 gaccaagagt ccattgatga ccgcgaatat gccagtgtcc tttaaagtta gcaacatctt
    29341 tttgaagtct tctggcttag gcttttcttc gcttgtttcg agcaagagga ttttcccttc
    29401 ccagtctgac aagtcaggga aaagtttgta tttttggcag agctccgtgc tatctgcgta
    29461 tcgagagttg tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga ttttcccctc
    29521 gaattgggcc cttccttgca acaagtcaaa acctgtattt gtatgactga cacgaggtgt
    29581 tcccagggcc gtgggactaa aatcagttcg ttcctcatac caaacgtcac tagggcggat
    29641 ttctgaaatt cttcccgtct caatcaattc tttaaagtag tgaaggctat aggctagcat
    29701 ttctttgtct aattcacaaa tgtctgctaa aaaggattga ccataaaaag tcttgattcc
    29761 taatttatgc aacatgaggt ggttcatggt tgtatccgag aagccaagaa aaattttttg
    29821 tttgataacc ttttggagtt ggtcattttt aaaaagataa ggtagcaagc gataggtatc
    29881 gtctccaccg atggcacata ggatcatgtc gatgctatca tcagaaaagg catgaatcaa
    29941 atcctctgca cgagcttcag gatggtcctt gataaagtct aatcctttta acgaatgggg
    30001 caaaaagatg ggattgagtc ccagatcctt gagacgttgg atacccaagt ccacttcgtg
    30061 tttgacaaaa tcctctccga taatgccact agataaacta acaataccaa tagtagaaac
    30121 catatctcat cctcctagaa atagattgag cctattttat cacaaaatat aagagaaagc
    30181 tatgtgggat ttcagaagaa tacttttaat actcttcgaa aatctcttca aatcacgtca
    30241 gttttatttg caacctcaaa gctgtgcttt gagcaacctg cagctagctt cctagtttgc
    30301 tctttgattt tcattgagta taactcaaaa aagtaagtga aaaagcaacc gcacctgcag
    30361 ttgcttttat cgttttctta ttcttgatag cgtgttggtc ctgcacttgc actacggata
    30421 ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg ctgctccaat aatagctagt
    30481 ggcaatggat ccagtactgg gttaaggcta gctggtagga agcttgttgc aaagaagaca
    30541 agcaaccaaa ggaacataga agctaggata actagtacag atttccagaa aggtggacgt
    30601 tgactgcgat ccatatctgg tccatagtat tggtaaacaa agtagtacat caagtagaag
    30661 gcaaatccac caaccagtcc aactaataga agagtaatca atccatagcc gaaagcttga
    30721 tctgccgcaa agaaggttgt gagggcgctg acaagggcaa agaggctagt gatgaaaaga
    30781 gctgagtcca taatcatcag ttttgggtca tcattttctt ttggatgctc tttttcgtac
    30841 tgctctttga cagtgaagct atgagcccaa tgagttggtg cgccgtatag ggaacgggca
    30901 gttgtacctt tagattgctc ctcaaggatt tggggaatga cttcctcaaa aatagtctgg
    30961 atttcagcgt ctgttttccc atctttgatg aattgttggg tagcaatgtg gacaaactct
    31021 tggtttttct tagttaattt ttgtagatca atttgagaca taggaactcc tcttagaacc
    31081 attttttatg gatgagatag agagtgagcg agacactcat agcaaaggcg ataaagacga
    31141 ttaaccagaa ggcatttggc tctccgttta ggggaatttc attatcctta aagttcatcc
    31201 cgtaggcaga aaagaccatg gttgggatgg acatgacgat ggtcacaagg gccaaggttt
    31261 tcatgatgtt gttctggttg ttagaaatga tagaggcaaa ggtctctgtc atagaatgca
    31321 agacgtttcc ataaatatct gccatctcga tggcctgttg ggtttcaatc agggtgtctt
    31381 caagcaggtc ttcgtcctca aggtatttct tgatattgct ggttgaactg gtcaatttct
    31441 taatcacgcg ctcatttgtt ttgagggagg ccttgaaata gacgatagtt ttttccaatt
    31501 ccatgagctc aatcaattct tcattacgag ttgattgatg cagttgactt tcgatttgtt
    31561 cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg cgataaagaa
    31621 tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga cggttgataa
    31681 agacatcaag gacaggtagt ggttccaaac acgtagtgat aatggtttcc tcagtgatga
    31741 taataccaag cgggatggtt acgtagtagg tgcggttatt tctttcctcc gtgaccggca
    31801 cgtctacgat aatcagggta tactcgtctt caatggtaat acgagacatt tcttccgcat
    31861 cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt tcgagtgatt
    31921 cattttgagt cggattgacg agattgatcc aagtacccgg ttcaagcgta tcgatctctt
    31981 taaattcagt tgttgtagag agaaaaactt gtttcatatc ccttatcctt tctcattttt
    32041 cagatttttt cacactgtac tattatacta caaaatcggc cttttgggta atagaatctc
    32101 actttttttg gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa
    32161 attgtcattc atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga
    32221 gacaagttgg ttgtcgtgac tggcttgtca ggttcaggga agtccagtct ggcttttgat
    32281 actctctatg cggagggaca acgtcgctat gtagagagtt tgtctgccta cgctcgtcag
    32341 ttcttgggaa atatggaaaa accagatgta gatgccattg atggtctcag cccagctatt
    32401 tccatcgacc agaaaacgac tagtaaaaat cctcgctcga cggtgggaac gacgactgaa
    32461 atcaatgact atctgcgtct cctctacgca cgtgtgggga cgccttactg tatcaacgga
    32521 catggagcta tcaatgcttc ttctgtggag caaatcgttg ataaggtttt ggagttacct
    32581 gaacgccagc gcttgcagat cttggctcct gtcatccgca agaaaaaagg ccaacataag
    32641 agtgttatcg agaaggttca gaaagacggg tatgttcgtg ttcgtgtgga tggggaagtc
    32701 tatgatgtga ccgaagtgcc agagttgtct aagagcaagc aacacaatat cgatgtcgtg
    32761 gttgaccgta ttgttatcaa ggagggcatt cgtagccgtc tctttgattc cattgaagct
    32821 gcccttcgta tcgcagaagg ttatgtcatt atcgacacca tggacgactc ggagttgctc
    32881 ttctctgagc attatgcctg tccagtttgt ggatttactg tcccagagtt agaacctcgt
    32941 ctcttctctt tcaatgctcc ctttggctct tgtagtgagt gtgacggctt ggggattaag
    33001 ctggaggtgg atactgattt ggtagtgcca gatgccagca aaaccttaca tgagggagcg
    33061 ctggcacctt ggaatcctat ctcatccaac tactatccaa acatgttaga gcaggccatg
    33121 aaagtctttg gagtggctat ggataagcct tttgaggacc tgtcagaaga agataagaac
    33181 ttgattctct acggctcaga tggtaaggaa ttccatttcc attatgaaaa tgaatttggt
    33241 ggtgtgcgcg atatcgacat tccgtttgag ggagttatca ataatatcaa acgtcgttac
    33301 catgaaacca atagcgatta cactcgcact cagatgcgtc tctacatgaa tgagctgacc
    33361 tgcggaacct gtcaaggcta tcgtctcaat gaccaggcct tgtctgtccg tgtgggcggc
    33421 cagcaagggc cacatattgg agaaatctca gacctgtcta tcgctgacca cttggacttg
    33481 gtgagccagt taactttgtc tgaaaatgaa gccatcattg ctcgtcccat tctcaaggaa
    33541 atcaaggatc gtttgacctt ccttaataat gtgggtctta actatctaac cctgtcacgt
    33601 tcagcaggaa ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt
    33661 tccaacctat caggtgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg
    33721 gacaatgacc gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc
    33781 gtggtggaac acgacgaaga taccatgcgt gaagctgatt atctgattga cgttggtcct
    33841 ggtgccggtg tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc
    33901 aacagcaagt ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa
    33961 gagcgccgtg tcggaaatgg tcgttttatt gaagtgacag gagcgcgtga gaacaacttg
    34021 caaaatgtca cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt
    34081 tcagggaaat cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac
    34141 cgtaattcag acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt
    34201 ttgattgata ttaaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat
    34261 acaggagttt ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga
    34321 ggctacaaga aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca
    34381 ggtgacggga ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa
    34441 gtttgccacg gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat
    34501 atttcgcagg tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg
    34561 aaaattcaac gcaaactcca gaccatcaag gatgtaggtc taggctatgt gaccttggga
    34621 cagccagcta ccaccctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc
    34681 cacaaacgct cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat
    34741 acagaggaca ttgctcgcct gctcaaggtt ttagctcgct ttgtagacgc cggcaataca
    34801 gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg
    34861 ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta
    34921 gctgccaacg aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa
    34981 acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa ctagatggta tcatcatcaa
    35041 caatcttaaa aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat
    35101 cagccgtgac cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga
    35161 aaccagtggt tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt
    35221 taaggacatg aacttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca
    35281 ccgtatgcag gcagcttttg caggtttgaa cttgcttcca caaactcagt ttgtggaagg
    35341 tcttcgtatg attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc
    35401 agaccaagct ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg aaattgagat
    35461 tgccaacttc cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac
    35521 gatcctagct agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt
    35581 ggagttggga gaagccatca ccatggactt cggctgtctc tatgaccact atgtcagtga
    35641 tatgacccgg actatctatc tagggcatgt tagcgatgag caggcagaga tttacaatac
    35701 ggttctaaaa gctaaccaag ccttgattga ccaagctaag gtaggcttag gtttccgtga
    35761 ctttgacaaa atccctcgtg atattatcat tgaggcaggt tatggtgact actttactca
    35821 cggcattggc cacggtattg gtctggatat ccatgaggaa ccctacttta gtcagacttc
    35881 tacagaaact attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg
    35941 caaatatggc gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt
    36001 gaccctagct ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa
    36061 atgacgaaaa aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta
    36121 taatagacta aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat
    36181 acagtctcaa gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta
    36241 agttataaag aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt
    36301 ctaaccaaaa cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa
    36361 gcccttggag tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa
    36421 acaccgagaa ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac
    36481 aaggaagacg atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa
    36541 gcacgtttgc gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta
    36601 ttttaatttc aaaaagaaag aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt
    36661 tcctttttgt cctggttggt tgcggacaga aaaaagaaac tggaccagct acaaaaacag
    36721 aaaaagatac gcttcagtcg gcattgccag ttattgaaaa tgctgagaag aatacagttg
    36781 taactaagac tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta
    36841 cttacaaaga caagactttt ttgagtctaa ctatccaaca aaaacgtcca gtctctgatg
    36901 agttgaagac ttatattgac caacatggag tggaggaaac tcaaaaagct cttcttgaag
    36961 cggaggagaa ggataagtct atcattgaag ctcgtaaact ggcaggtttc aaacttgaaa
    37021 caaaactatt gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg
    37081 atgtcaagaa ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga
    37141 aaaatgaacc aagcaaatat atttcagata gattggcaaa tggcgcgaca gaacaataga
    37201 aaatccaaat aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac
    37261 tattctaagg aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt
    37321 ggacgattcc aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa
    37381 cgataagggt tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc
    37441 ctacgttcct cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat
    37501 cgttgaggaa ttggttcgct actacctcaa agggcaagga gtcgatctat aacctatgag
    37561 aattatggga ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg
    37621 ttttacagct caagggcttg aaatcatcca gataaatgaa gaacaaggca aatttggttt
    37681 tgaccgcgtt aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc
    37741 taaaaacatg aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa
    37801 gctagaagag ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc
    37861 tgctgagcgc atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat
    37921 tgataagtta gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa
    37981 aggagaggct atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact
    38041 agtagatgag caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga
    38101 agaatttggt aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg
    38161 acaagttgaa atccaagctt actcattcat tgaaaatgaa gatggaacag aaggcgaatt
    38221 gcaaccaatc ccagaagact cagaagacga atggaacatg attgaagaag tcttcaacag
    38281 ctttatggag gagtgataca gtctgggaga ctgtatcagc ccaactccca gaaatgggga
    38341 agagttggaa cgtccagtgg atgtttttag cccagttcct ttaaataaga gagaactggt
    38401 aggttcgggg ggacgttttt agccctgcgc tagaaattag aaacgcaggt agtctgagaa
    38461 actgtatcag cccaactccc agaaatgggg aagggttgga acgtccagtg gatgttttac
    38521 tccacgttaa tattcatagt tgctagtgat tagctaacca ggtaagaggt cgggacgaaa
    38581 atcctggcct tgtttttatt agtaaccata ctttaatgcg ataattgatt ggacttttgt
    38641 caaggagatg tgtatgtttg aagtagaaga atggctccat agtcggattg gtttaaattt
    38701 tcgatcaggt ttgggccgaa tgcagcaagc ggtggatttg ttaggaaatc ctgagcagtc
    38761 ttaccctatt atccacgtaa cagggactaa tgggaaagga tctaccattg cttttatgag
    38821 ggaattattt atggggcatg gcaaaaaagt tgcgaccttt acctcccctc atatcgtctc
    38881 tatcaatgac cgaatctgca ttaatgggca acctatagca gacgcagact ttatccgttt
    38941 ggctgatcag gtcaaggaga tggagaaaac gcttctgcaa actcctgacc agttgtcctt
    39001 ttttgaattg ctgaccttgg ttgcttttct ttattttagg gagcaagagg tggatttggt
    39061 tttattagaa gtgggaattg gtggcttact tgacacgacc aatgtggtaa ctggagagct
    39121 tgctgtcatc acctccattg ggcttgatca tcaagaaacc ttgggtgata gtctagaagc
    39181 aattgcagag cagaaagctg gtattttcaa ggctggtaag aaggcagtga ttgcgaaatt
    39241 gcctccagaa gctaggctta tctgtcagaa aaaagccgaa tctttagctg ttaaccttta
    39301 tcaggcaggt caagattttt taatgctgaa tggtgatttt tcaagctctt tactaaatct
    39361 ttcacagctg gacataggct tagaaggagt ctatcagcag gagaatgcag ccttggcgtt
    39421 gcaaactttt cttcttttta tgggagaagg aaaggaagct gttgatgaac aggctgtaag
    39481 aaaggccttg gaacagaccc attgggctgg tcgcttggag cgtattcgcc cacagattta
    39541 cttggatggt gctcataacc tccctgcctt gactcgcttg gttgagttta tcaaagaaaa
    39601 agagcaggaa ggttatcgac ctcaaatcct ctttggatcc ttgaaacgta aggattatca
    39661 agggatgttg ggttatctga ctgaaaattt acctcaagtg gaactcaaga tgactggctt
    39721 tgactatcaa gggtctttgg acgagacaga tgtaacaggt taccatgtaa ttccctctta
    39781 ccgagaattt atcagcagtt tcgaagaaag ggcagacgct caagacttgc tgttcgtaac
    39841 agggtctctc tattttatct cagaagtacg gggctacctg ctggaccgtg agcagataaa
    39901 ttgaccccct tttttgaact tgttatacta ggggaattgc tggttagaga aaatttctct
    39961 aaattggtag cagaaaggaa atccatcatg aaattaaaaa gattcacact ttctcttgct
    40021 tctctagcaa gttttagtct cttagtagct tgttcacaaa gagctcaaca ggttcaacag
    40081 cctgctcaac agaataccaa tactgcaaat gcagggggta accaaaatca agcggctcca
    40141 gtacaaaacc aacctgttgc tcagccgacc gatattgatg ggacttatac tggtcaggat
    40201 gacggagacc gtatcacttt agtggtaact ggaacgactg gtacatggac tgagctcgaa
    40261 tctgacgggg atcagaaagt caaacaggtt acatttgatt cagcaaatca acgcatgatt
    40321 attggcgatg atgtcaaaat ttacactgta aacggtaatc aaatcgtcgt agatgatatg
    40381 gatagagacc catcggacca aatcgtttta actaaataag actatgcaag tagaaagggc
    40441 tggatttttc agccttttta cttttaccta gaaaataatc ataaatactt gccttctacc
    40501 gaatacctgc gttatactag tatcaattac ttgtttttag cattcaaact atcaaggagg
    40561 ggatatgaaa tataggaaat ttcaattatt gatgtccaag tatggcttta gtctttcgat
    40621 tatgttactt gaactttgtc ttgtttttgg tctctttctt tatttaggac gcatggctcc
    40681 cattttatgg attactgtcc tcattctact gagtatcatc acaatcattt cgatagtcaa
    40741 ccgtaatacg actcctgaga ataaggtaac ctggttgtta gtagcctttg tgccagtatt
    40801 tggtcccttg ctctatctga tgtttggtga aaggcgattg tccaaaaaag aaatcaaaca
    40861 actgaagaag ctaggctcta tgcatttcca agaagcaaat agccagctac taaaagagaa
    40921 attaaaagaa agtgacaagg cagcttatgg agtcatcaag tccttattga gtatggatac
    40981 caatgctgac atctatgatc aaactgcctc tacatttttt cctaacggag aagctatgtg
    41041 gaaaaagatg gtagaagatc ttaaaaaggc tgagaaattt attttcttgg aatattacat
    41101 tatagaagaa ggtttgatgt ggaatcgcat actagatata ctagagcaaa aggtagctca
    41161 gggtgtagag gttaagatgc tctatgatga tatcggctgt atggctactt taacaggaga
    41221 ttatgcacat cgacttcgtc agctgggcat cgaggcccat aaattcaata aagttattcc
    41281 tcgtttgaca gtggcttata ataacagaga tcatagaaaa atattgattg ttgatggtca
    41341 gatagcctat actggtgggg tcaatctggc agatgagtac attaaccacg tcgagagatt
    41401 tggttattgg aaggatagtg gaattcgctt agacggacta gcagtaaaag ctctgacacg
    41461 cttatttttg accacttggt acattaatcg aggagaaatt agtgattttg atcaatatca
    41521 tttagaaaat cattctatcc cgagtgacgg tttaaccatt ccatacggaa gtggacccaa
    41581 gccaattttt cgagcgcagg tagggaaaaa agtttatcag agtttaatca atcaagcaac
    41641 agaatcggtc tatattacga caccttattt gattatagat tatgatttaa cagagacaat
    41701 caaaaatgca gctatgagag gggtcgatgt tcgaattatc accccttaca taccagataa
    41761 gaagttcatt cagttagtca cgagaggagc ttatcccgac cttctttctg ctggtgttcg
    41821 gatttatgag tatagtccag gttttattca tagtaagcag atgttggtag acgaagattt
    41881 tgcggtggtg gggacaatca atctcgacta ccggagcttg gtacaccatt atgaaaatgc
    41941 agtcttactc tataaaactc cttctataag ggaaatcgcc cgagattttc gaaatatatt
    42001 tgcagattct caggaagtct atcctcattc tatcaaaacg agctggtatc aaaagcttgt
    42061 aaaagaaatc gcccagctat tcgcccctat cttataagaa atctagaact taggatacaa
    42121 accagaccta tttttcttgt cttttacgaa tagaaagaaa gaggagggga attcatgcta
    42181 actaaggaag aagtgaatga tatgattgag ttcaaacaga cacatttaca ccgctttcgg
    42241 gaaattgaaa cctttgtgaa actatgcaaa aaatcactca aacagccatc gcaagctgac
    42301 aatcctagga ctttttgata tactaagaca gataaattga acaggagaaa cgatatgagt
    42361 gtgtatggta gagtagaaga agttcataag gagaatcgtg aacctctaga ataccaaatc
    42421 gaacaagaat cgcatcatcg tgaatcaagt cgtcttcctt tggtgaaaat tttactatgg
    42481 agtacgcttg taacggggat aactctagga gtgccgctat tactcgactt aatgagtgca
    42541 caagaagtgc aggattttta tgcaggttgg gcgcttcatc agacagggaa gatttacagc
    42601 gactattatg gaagtcaagg tttgctttat tatttgctga cttacgtgag tcagggcgga
    42661 tttttctttg ccatctttga gtggttagcc ttggtagcag gaggattttt cctttttaga
    42721 tcagcggaca ccttgacaga gcaaggagac caagctggac atctggtgac tattttttac
    42781 atgctagtta caggtcttgc ttttggtgga ggctatgcga ctcttttagc gcttcctttc
    42841 ttattcgcag cctttagttt agttgcggct tacctaagca atccaagcca tgataaggga
    42901 tttgtacgga ttgggctagc tttggcaggc ggatttttct ttgctccctt atcatcgctc
    42961 ctgtttattg ctgtagtgag tttaggcttg ttggtcttta accttgggca tagacgtttt
    43021 gtgcatgggt tttatcagtt tcttgcagtg gctttaggtt tttcacttgt cttttatcca
    43081 actgcctact atagtgctgc aacaggaagt tttggggatg cgattagtgg tattcgttat
    43141 cctattgaca gtattcgctt tgattttact tctaaaattt tagagaatat gtttttttat
    43201 ggcttgttgt cccttggttt gggatttgtg gtttgtatct ttttaggtct ctttcaatcc
    43261 aaacccttta aactatacgt catttcggtt cctgcaagtc ttgtggtaat tttaggtttg
    43321 attttacttt tcttttcaca agagcctctg cacgcttctt atttgatggt cgtcttccct
    43381 gttttcctac ttttattggt aaccaatatt aagagtcaac agagggggcg tagtgctaga
    43441 agaagccgaa gagaaacgcc agttagccta tggagtcgtt tcttcaaagg aaatctatat
    43501 ctgctagttt ttgggtttgt ctatcttttg tctgttcctt ttttgatgaa gtttgtcctt
    43561 tatccagtac cttatcaaga acgtaatcgt cttgctgatt tggtaaaaga ggagacaaat
    43621 acggaagatg ctatctatgc atgggatgat actgcgactc tttatcgtaa gagtgagcgc
    43681 ttgtcgccat cggcgatttt gtccccgttg cactatacag caactgagga aaatcgtaat
    43741 aagttactta atgacttgaa agaaaaacaa cctaaggtga ttgtggtaaa tgacaaggtg
    43801 gtagtctggt ctgaagtgga aacactctta aaagaaaatt accaacaagt aaagactgat
    43861 tactcagagt ttaaagtcta taaaattaaa taaccaaatc aatatcttgt gtatttttaa
    43921 aaattttagg atttttaaca caagatattg atttttcttt ttagagtggt ataatacttt
    43981 ttagaaagaa cattttagaa aagagcatgc gtatgattgc actagaagaa aaaattacaa
    44041 ttttgccaac tctcttcgtc gagaaacgag atgggagacg tgttgtattt gatgtggaca
    44101 agattgacaa ggctctccac aaggcggctg acaaggttat ggatgtgaca cccctggttg
    44161 aaaaacgcct caatgatctg actgagcgaa ttattacaga aattcatagt cgctttccac
    44221 agggaattaa gatttacgaa attcaaaata tcgtagaaca tgaactcctt gaagccaaag
    44281 aatatgcgct ggctgaggag tatattactt atcggacaca gagggatttt gagcgctcaa
    44341 aagcgacgga tatcaacttt agtattcata aacttctcaa caaagaccag acagttgtca
    44401 atgaaaatgc taataaagac agtgatgtct ttaacactca gcgtgatttg acagcaggga
    44461 ttgttgggaa atcaatcgga ctgcaaatgc ttcctaagca cgtagccaat gcccaccaaa
    44521 agggggatat ccactatcac gatttggact acagtcccta tacccctatg accaactgct
    44581 gtttggttga ttttaagggt atgttggaaa atggttttaa gattggaaat gcagaggtag
    44641 agagtcccaa gtctatccag actgcgacag cacagatttc tcaaatcatt gccaacgttg
    44701 cttctagcca gtacggtggc tgttcagctg accgtatcga tgaaattttg gcgccttatg
    44761 cagagaagaa ctatcaaaaa catctcaaag atgcagaaga gtgggtattg cctgaaaaac
    44821 gggaagatta cgcttggaag aaaacgcaaa aggacatcta cgatgccatg caatctcttg
    44881 agtatgaaat caatactctc ttcacttcaa atggacaaac accttttact tcgttaggtt
    44941 ttggtctggg aaccagtcgt tttgaacgag aaattcaaaa agctatttta aacattcgaa
    45001 tcaagggtct tggttcagaa caccgtacgg ctatctttcc taaacttatt ttcactctga
    45061 aaagaggcct taatttagag gaaggaactc ccaactacga catcaagcag ttggctcttg
    45121 agtgtgcaac caaacggatg tatccagatg ttttatctta cgataagatt gttgacttga
    45181 caggatcctt caaggtgcct atgggttgcc gttctttcct ccaaggatgg aaggatgaaa
    45241 atggtgtaga agtcaattca ggtcgcatga atctgggtgt tgtgacggtt aatctgcctc
    45301 gtattgctct tgagtctgaa ggtgatatga ataagttctg ggaaatcttc aacgagcgaa
    45361 tgaatatcgc agaagatgct cttgtttacc gtgtcgaacg cactaaagag gcgacaccag
    45421 caaatgctcc tattctttat cagtacggtg cttttggcca tcgtctaggt aaagaagaaa
    45481 gtgttgacca gctctttaag aatcgtcgtg cgaccgtttc gctgggctat atcggcttgt
    45541 atgaagtagc gacagttttc tttggtaaca gctgggaaag taatccagat gctaaggaat
    45601 tcacgctaga catcattcac gatatgaaac gccgtgtaga agagtggtca gaccaatatg
    45661 gctaccattt ctctatctac tcaacaccat ccgaaagtct gacagaccgt ttctgccgac
    45721 tagatataga caagtttggc tctattcctg atatcacaga caaggaatac tacaccaact
    45781 ctttccacta cgatgttcgt aaaaatccaa caccgtttga aaaattggac tttgagaaag
    45841 tctatccaga agcaggtgcg tcaggtggtt tcatccatta ttgtgagtat ccagtccttc
    45901 agcaaaatcc aaaggccttg gaagctgtct gggattatgc ttatgaccgt gtaggctatc
    45961 taggcaccaa tactccgatt gaccgttgct acaagtgtga ctttgaaggg gattttgaac
    46021 caactgagag agggtttgct tgtccaaact gtggcaatag cgatcctaaa acagtagacg
    46081 ttgttaaacg gacttgtggc tatcttggca atcctcaagc aagaccgatg gtcaacgggc
    46141 gtcacaagga aatcgctgcg cgtgtcaaac atatgaatgg ttcaacgatt aaaatagctg
    46201 ggcatcaagt aacaaattag aaagaaatga aatggggaaa tatcaactag acgataaggg
    46261 gcgcgcacaa gtgacccgtt atcacgagaa atactctaaa ggtggagctg gtaagaaaga
    46321 acgcttgctt agcttcagag aacaattttt aaacaagaac aagaaaaaat aaaagtgaga
    46381 gccagctctc gcttttctca tagtgggagg taaggatgga attacgcaga ccaagattag
    46441 cggataagaa agctgtttta gatatgatga cagagtttga aaagagccaa tcagcccatg
    46501 atggaggatt ttgggataca gagaactttg tgtatgaaga gtggttggaa agcaatcagg
    46561 aacaggaaat ggggattaat ctgcctgaag gatgggttcc tgcaattcag ttagtggctt
    46621 tttctgagaa aggtcaagca gttggatttc ttaatctccg gttgcgcctc agtaactttc
    46681 tactagaaga aggtgggcac attggctact ccatccgtcc atctgaaaga ggcaagggtt
    46741 atgcaaaaga gactctccgt cagggcttgc aagttgctaa ggaaaagaac atcaagaaag
    46801 ctctggtgac ctgtagcgtg aataatcctg ctagcagagc agtcattcta gcaaatggtg
    46861 gaatatttga ggatgctcac aatggagtcg agcgttattg gatagaggta gcgaatgaat
    46921 aatccaaaac cacaagaatg gaaaagcgag gaacttagtc aaggtcgtat cattgactac
    46981 aaggccttta actttgtgga cggcgaaggc gtgcgcaact ctctctatgt atcaggctgt
    47041 atgtttcact gcgagggatg ttataatgtt gcgacttggt cttttaatgc tggcattccc
    47101 tatacagcag aattagaaga gcagatcatg gcagaccttg cccaacccta tgttcaaggc
    47161 ttgactttgc tgggagggga accttttctc aatactggca ttctcttgcc tctagttaaa
    47221 cgcatccgaa aggaattgtc agacaaggac atttggtcct ggacgggcta cacttgggaa
    47281 gaaatgatgt tggaaactcc agataaactg gaactcttat cattgattga cattcttgtc
    47341 gatggacgat acgatcgaac taagagaaat ctcatgctcc agtttcgagg ttcgtccaac
    47401 caacgaatta tcgatgtgca aaaatcgctc aaaagtgggc aagtagtgat ttgggacaag
    47461 ctcaatgacg gaaaagaaag ctatgaacag gtgaagagag aatgaagaaa aaagacttag
    47521 tagatcaact agtctcagag atcgagacgg ggaaagtcag gacactggga atatacggtc
    47581 atggagcttc aggtaaatca acctctgcac aggaattgta ccaagcttta gattctacta
    47641 cagtaaattt gctagaaaca gatccctata tcacctcagg acgccatctg gtagtaccca
    47701 aggacgcgcc gaatcaaaag gtgacagccg gtctgccagt ggcgcatgaa ctggagagtt
    47761 tgcagagaga tatccttgcc ttgcaggcga gtatggatgt cttgacaatt gaagaacctt
    47821 ggaaggctag tgaggtcttg tctggagcca aaccaatttt gattgtcgaa gggatgtctg
    47881 ttggctttct acccaaggaa ctctttgaaa aaaccatctg tttctacacg gatgaggaga
    47941 ccgaattaaa gcgacgcctt gctagagata cgactgtgag aaatcgtgat gcatccttta
    48001 tattggctag ccatcagatg agacgggagc agtatctgcg atactataaa gaaactgagt
    48061 ctaaggcgga tatcttagtg gatcaatcag aagataaatt tgatgtcaag aggacttaac
    48121 ttatgtatag aagaaatata gaagaaaatc cctaatttta gaaagaaaaa gtaggaaaac
    48181 agtttcatcc caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca ggggatttgt
    48241 gttattctat tatggtgctg taaattacag ccttagtttt gatgcaagag gttgcgacac
    48301 gctcggttgc attgccacgc aacaccgtgt cggttttctt gtggagctag cctattatct
    48361 taaatagacg aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg tttgaaagct
    48421 tacgaacacc gtacgcttga cacagcggct gcaaaaatcg tagaatcagc tactcgtaca
    48481 ggtgcacaag ttgcgggtcc aatcccactt ccaactgaac gtagcctcta cacaatcatt
    48541 cgtgcgactc acaaatacaa agactctcgc gaacaatttg aaatgcgtac acacaaacgt
    48601 ttgatcgata tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa attggatctt
    48661 ccaagtggtg taaacgtaga aatcaaactt taatctaaaa tataagagag cagaggctgg
    48721 tgtttcaatc taattgaaca cgggctaaac ttggtgtgaa aaagataaac ttcctcgcgt
    48781 ctgctagaca ctgtgtcagt ttcctatttt cacgttgagt ttgacgccct ttgtatctta
    48841 gacttgagca taaaaaacgc tcgttaaaaa ctttttgaat aaaaaatata gaaaaggaac
    48901 tattttctca tgacaaaagg aatcttaggg aaaaaagtgg gaatgactca aatcttcact
    48961 gaagctggcg aattgatccc tgtaacagtt attgaagcaa ctccaaacgt tgttcttcaa
    49021 gttaaaactg ttgaaacaga cggatacaac gctatccaag ttggtttcga tgacaaacgc
    49081 gaagtattga gcaacaaacc tgctaaagga catgtagcga aagctaacac ggctcctaag
    49141 cgcttcattc gtgaattcaa aaacgttgaa ggcttggaag ttggtgctga aattacagtt
    49201 gaaacattcg cagctggaga cgttgttgac gtaactggta cttctaaagg taaaggtttc
    49261 caaggtgtta tcaaacgcca cggacaatca cgtggaccaa tggctcacgg ttctcgttac
    49321 caccgtcgtc caggttctat gggacctgtt gcacctaacc gcgtattcaa aggtaaaaac
    49381 cttgcagggc gtatgggtgg cgaccgcgta acaattcaaa accttgaagt tgtacaagtt
    49441 gttccagaaa agaacgttat ccttatcaaa ggtaacgtac caggtgctaa gaaatctctt
    49501 atcactatca aatcagcagt taaagctggt aaataataaa gaaaggggaa atcagtcaca
    49561 atggcaaacg taacattatt tgaccaaact ggtaaagaag ctggccaagt tgttcttaac
    49621 gatgcagtat ttggtatcga accaaatgaa tcagttgtgt ttgatgtaat catcagccaa
    49681 cgcgcaagcc ttcgtcaagg aacacacgct gttaaaaacc gctctgcagt atcaggtggt
    49741 ggacgcaaac cgtggcgtca aaaaggaact ggacgtgctc gtcaaggttc tatccgctca
    49801 ccacaatggc gtggtggtgg tgttgtcttc ggaccaactc cacgttcata cggctacaaa
    49861 cttccacaaa aagttcgtcg cctagctctt aaatcagttt actctgaaaa agttgctgaa
    49921 aacaaattcg tagctgtaga cgctctttca tttacagctc caaaaactgc tgaatttgca
    49981 aaagttcttg cagcattgag catcgattct aaagttcttg ttatccttga agaaggaaat
    50041 gaattcgcag ctctttcagc tcgtaacctt ccaaacgtga aagttgcaac tgctacaact
    50101 gcaagtgttc ttgacatcgc aaatagcgac aaacttcttg tcacacaagc agctatctct
    50161 aaaatcgagg aggttcttgc ataatgaatt tgtatgatgt tatcaaaaaa cctgtcatca
    50221 ctgaaagctc aatggctcaa cttgaagcag gaaaatatgt atttgaagtt gacactcgtg
    50281 cacacaaact tttgatcaag caagctgttg aagctgcttt cgaaggtgtt aaagttgcca
    50341 atgttaacac aatcaacgta aaaccaaaag ctaaacgtgt tggacgttac actggtttta
    50401 ctaacaaaac taaaaaagct atcatcacac ttacagctga ttctaaagca atcgagttgt
    50461 ttgctgctga agctgaataa tctaaggagg aaatatcgtg ggaattcgtg tttataaacc
    50521 aacaacaaac ggtcgccgta atatgacttc tttggatttc gctgaaatca caacaagcac
    50581 tcctgaaaaa tcattgcttg ttgcattgaa gagcaaggct ggtcgtaaca acaacggtcg
    50641 tatcacagtt cgtcaccaag gtggtggaca caaacgtttc taccgtttgg ttgacttcaa
    50701 acgtaataaa gacaacgttg aagcagttgt taaaacaatc gagtacgatc caaaccgttc
    50761 tgcaaacatc gctcttgtac actacactga cggtgtgaaa gcatacatca tcgctccaaa
    50821 aggtcttgaa gtaggtcaac gtatcgtttc aggtccagaa gcagatatca aagtcggaaa
    50881 cgctcttcca cttgctaaca tcccagttgg tactttgatt cacaacatcg agttgaaacc
    50941 aggtcgtggt ggtgaattgg tacgtgctgc tggtgcatct gctcaagtat tgggttctga
    51001 aggtaaatac gttcttgttc gtcttcaatc aggtgaagtt cgtatgattc ttggaacttg
    51061 ccgtgctaca gttggtgttg tcggaaacga acaacatgga cttgtaaacc ttggtaaagc
    51121 aggacgtagc cgttggaaag gtatccgccc aacagttcgt ggttctgtaa tgaaccctaa
    51181 cgatcaccca cacggtggtg gtgaaggtaa agcaccagtt ggtcgtaaag caccatctac
    51241 tccatggggc aaacctgctc ttggtcttaa aactcgtaac aagaaagcga aatctgacaa
    51301 acttatcgtt cgtcgtcgca acgagaaata atattaaact agtcgcttaa gcaactagta
    51361 aatccgccag ctcggtagcg ctccatagga gtgcaagccg ctgtggtaca acatttaaag
    51421 gagaaaatat aaaaatggga cgcagtctta aaaaaggacc tttcgtcgat gagcatttga
    51481 tgaaaaaagt tgaagctcaa gctaacgacg aaaagaaaaa agttattaaa acttggtcac
    51541 gtcgttcaac gatcttccca agtttcattg gttacactat tgcagtttat gacggacgta
    51601 aacacgtacc tgtttacatc caagaagaca tggtaggcca caaacttggt gaatttgcac
    51661 caactcgtac ttacaaaggt cacgctgcag acgacaagaa aacacgtaga aaataaggag
    51721 aacataaatg gcagaaatta cttcagctaa agcaatggct cgtacagtac gtgtttcacc
    51781 tcgtaaatca cgtcttgttc ttgataacat ccgtggtaaa agcgtagccg atgcaatcgc
    51841 aatcttgaca ttcactccaa acaaagctgc tgaaatcatc ttgaaagttt tgaactcagc
    51901 tgtagctaac gctgaaaaca actttggttt ggataaagct aacttggtag tatctgaagc
    51961 attcgcaaac gaaggaccaa ctatgaaacg tttccgtcca cgtgcgaaag gttcagcttc
    52021 accaatcaac aaacgtacag ctcacatcac tgtagctgtt gcagaaaaat aaggaggtaa
    52081 aatcgtgggt caaaaagtac atccaattgg tatgcgtgtc ggcatcatcc gtgattggga
    52141 tgccaaatgg tatgctgaaa aagaatacgc ggattacctt catgaagatc ttgcaatccg
    52201 taaattcgtt caaaaagaac ttgctgacgc agcagtttca actattgaaa tcgaacgcgc
    52261 agtaaacaaa gttaacgttt cacttcacac tgctaaacca ggtatggtta tcggtaaagg
    52321 tggtgctaac gttgatgcac tccgtgcaaa acttaacaaa ttgactggaa aacaagtaca
    52381 catcaacatc atcgaaatca aacaacctga tttggatgct caccttgtag gtgaaggaat
    52441 tgctcgtcaa ttggagcaac gtgttgcttt ccgtcgtgca caaaaacaag caatccaacg
    52501 tgcaatgcgt gctggagcta aaggaatcaa aactcaagta tcaggtcgtt tgaacggtgc
    52561 agatatcgcc cgtgctgaag gatactctga aggaactgtt ccgcttcaca cacttcgtgc
    52621 agatatcgat tacgcttggg aagaagcaga tactacatac ggtaaacttg gtgttaaagt
    52681 atggatctac cgtggtgaag ttcttccagc tcgtaaaaac actaaaggag gtaaataacc
    52741 aatgttagta cctaaacgtg ttaaacaccg tcgtgaattc cgtggaaaaa tgcgcggtga
    52801 agcaaaaggt ggaaaagaag tagcattcgg tgaatacggt cttcaagcta caactagcca
    52861 ctggatcact aaccgccaaa tcgaagctgc tcgtatcgcc atgactcgtt acatgaaacg
    52921 tggtggtaaa gtttggatta aaatcttccc acacaaatca tacactgcta aagctatcgg
    52981 tgtgcgtatg ggatctggta aaggggcacc tgaaggttgg gtagcaccag ttaaacgtgg
    53041 taaagtgatg ttcgaaatcg ctggtgtatc tgaagagatt gcacgtgaag cgcttcgact
    53101 tgctagccac aaattgccag ttaaatgtaa attcgtaaaa cgtgaagcag aataaggaga
    53161 aggcatgaaa cttaatgaag taaaagaatt tgttaaagaa cttcgtggtc tttctcaaga
    53221 agaactcgcg aagcgcgaaa acgaattgaa aaaagaattg tttgaacttc gtttccaagc
    53281 tgctactggt caattggaac aaacagctcg cttgaaagaa gttaaaaaac aaatcgctcg
    53341 tatcaaaaca gttcaatctg aagcgaaata atagactagg gaaggagaaa tttcaatgga
    53401 acgcaataat cgtaaagttc ttgttggacg tgttgtatct gacaaaatgg acaagacaat
    53461 cacagttgta gttgaaacaa aacgtaacca cccagtctat ggtaaacgta ttaactactc
    53521 taaaaaatac aaagctcatg atgaaaacaa tgttgccaaa gaaggcgata tcgtacgtat
    53581 catggaaact cgcccgcttt cagctacaaa acgtttccgt cttgtagaag ttgttgaaga
    53641 agcggtcatc atctaatcaa acctgaaagg agaaaactga aatgattcaa acagaaactc
    53701 gtttgaaagt cgcagacaac agcggtgctc gcgaaatctt gactatcaaa gttcttggtg
    53761 gttcaggacg taaatttgca aacatcggtg atgttatcgt ggcatctgta aaacaagcta
    53821 ctcctggtgg tgcggttaaa aaaggtgacg ttgttaaagc agttatcgtt cgtactaaat
    53881 caggtgctcg tcgtgctgat ggttcataca tcaaatttga cgaaaacgca gcagttatca
    53941 tccgtgaaga caaaactcct cgcggaacac gtatctttgg cccagttgca cgtgaattgc
    54001 gtgaaggtgg cttcatgaag atcgtgtcac ttgctccaga agtactttaa tttttaggaa
    54061 caaactagtc ccctagcttc aagctagggt gcccttatgg gcgtaagaaa aatcaaggag
    54121 aaacctaatg tttgtaaaaa aaggcgacaa agttcgcgta atcgctggta aagataaggg
    54181 aacagaagct gttgtcctta ctgcccttcc aaaagtaaac aaagttatcg ttgaaggtgt
    54241 taacattgtt aagaaacacc aacgtccaac taacgagctt cctcaaggtg gtatcatcga
    54301 gaaagaagca gctatccacg tatcaaacgt tcaagttttg gacaaaaatg gtgtagctgg
    54361 tcgtgttggt tacaaatttg tagacggtaa aaaagttcgc tacaacaaaa aatcaggcga
    54421 agtgcttgat taatcacgaa ggaaaggaga agtataatgg caaatcgttt aaaagaaaaa
    54481 tatcttaatg aagtagttcc tgctttgaca gaacaattca actactcatc agtgatggct
    54541 gtgcctaaag tagataagat tgttttgaac atgggtgttg gtgaagctgt atcaaacgct
    54601 aaaagccttg aaaaagctgc tgaagaattg gcacttatct caggtcaaaa accacttatc
    54661 actaaagcta aaaaatcaat cgccggcttc cgtcttcgtg aaggtgttgc gatcggtgca
    54721 aaagttaccc ttcgtggtga acgtatgtac gaattcttgg ataaattggt atcagtttca
    54781 cttccacgtg tacgtgactt ccacggtgtc ccaacaaaat catttgatgg acgcgggaac
    54841 tacacacttg gtgtgaaaga acaattaatc ttcccagaaa tcaacttcga tgacgttgac
    54901 aaaactcgtg gtcttgacat cgttatcgta acaactgcta acactgacga agagtcacgt
    54961 gcattgctta caggccttgg aatgcctttt gcaaaataat ataggaggta aatctaatgg
    55021 ctaaaaaatc aatggtagct agagaggcta aacgccaaaa aattgttgac cgttatgctg
    55081 aaaaacgtgc tgcattaaag gcggcagggg actacgaagg tttatctaaa ttacctcgca
    55141 acgcctcacc gactcgttta cataatcgtt gtagggttac ggggcgccca cattcagttt
    55201 accgcaaatt tggtctgagt cgtatcgctt ttcgcgaact tgcgcataaa ggtcaaattc
    55261 ctggtgtaac aaaggcatct tggtaattta agatatcaag agcgtcaaaa ctccaagtaa
    55321 aaataggaaa cttgacgaag aaactaaagt ttctaggaaa gtttatcttt ttcacacaga
    55381 gtttagcccg ggttcaattg ggcttgccaa tttgaacacg agctacagct ttggcaaaaa
    55441 agaccaattt gctttggagc attgcttctg cattaaattg tctatttttg ctcgtgctgt
    55501 tacgctcttt gtatcatgta ttaactagca agtgcaactt gcaaactact agtaagagga
    55561 gaaaaacaaa atggttatga ctgacccaat cgcagacttc ctaactcgta ttcgtaatgc
    55621 taaccaagct aaacacgaag tacttgaagt acctgcatca aacatcaaaa aagggattgc
    55681 tgaaatcctt aaacgcgaag gttttgtaaa aaacgttgaa atcattgaag atgacaaaca
    55741 aggcgtcatc cgtgtatttc ttaaatacgg accaaatggt gagaaagtta tcactaactt
    55801 gaaacgtgtt tctaaaccag gacttcgtgt ctacaaaaaa cgtgaagacc ttccaaaagt
    55861 tcttaacgga cttggaattg ccatcctttc aacttctgaa ggtttgctta ctgataaaga
    55921 agcacgccaa aagaatgttg gtggtgaggt tatcgcttac gtttggtaaa atcaagatac
    55981 aaagctcgta aagaacaaag caaaattagg aagttggaga agtttgttta caaacaagcc
    56041 aacttatcta ttttgcacag ttcttagagc gtgttcagtt cagctcttga actaaataag
    56101 tatctgaacc ccgtgaaaac tggccgttct ggcctgacaa tttaacagga gaaaataaac
    56161 atgtcacgta ttggtaataa agttatcgtg ttgcctgctg gtgttgaact cgctaacaat
    56221 gacaacgttg taactgtaaa aggacctaaa ggagaactta ctcgtgagtt ctcaaaagat
    56281 attgaaatcc gtgtggaagg tactgaagta actcttcacc gtccaaacga ttcaaaagaa
    56341 atgaaaacta tccacggaac tactcgtgcc cttttgaaca acatggttgt tggtgtatca
    56401 gaaggattca agaaagaact tgaaatgcgt ggggttggtt accgtgcaca gcttcaagga
    56461 tctaaacttg ttttggctgt tggtaaatct catccagacg aagttgaagc tccagaagga
    56521 attacttttg aacttccaaa cccaacaaca atcgttgtta gcggaatttc aaaagaagta
    56581 gttggtcaaa cagctgctta cgtacgtagc cttcgttcac cagaaccata taaaggtaaa
    56641 ggtatccgtt acgttggtga attcgttcgc cgtaaagaag gtaaaacagg taaataatgt
    56701 tgagtggttg atcatcaacc accaacctat tttccaactt tgtgcatagc acacgattta
    56761 aaactaaaga ggtgaaaact gtgatttcaa aaccagataa aaacaaactc cgccaaaaac
    56821 gccaccgtcg cgttcgcgga aaactctctg gaactgctga tcgcccacgt ttgaacgtat
    56881 tccgttctaa tacaggcatc tacgctcaag tgattgatga cgtagcgggt gtaacgctcg
    56941 caagtgcttc aactcttgat aaagaagttt caaaaggaac taaaactgaa caagccgttg
    57001 ctgtcggtaa actcgttgca gaacgtgcaa acgctaaagg tatttcagaa gtggtgttcg
    57061 accgcggtgg atatctatat cacggacgtg tgaaagcttt ggctgatgca gctcgtgaaa
    57121 acggattgaa attctaatag gaggacacta gaaaatggca tttaaagaca atgcagttga
    57181 attagaagaa cgcgtagttg ctgtcaaccg tgttacaaaa gttgttaaag gtggacgtcg
    57241 tcttcgtttc gcagctcttg ttgttgttgg tgaccacaat ggtcgcgtag gatttggtac
    57301 tggtaaagct caagaagttc cagaagcaat ccgtaaagca gtagatgatg ctaagaaaaa
    57361 cttgatcgaa gttcctatgg ttggaacaac aatcccacac gaagttcttt cagaattcgg
    57421 tggagctaaa gtattgttga aacctgctgt agaaggttct ggagttgccg ctggtggtgc
    57481 agttcgtgcc gttgtggaat tggcaggtgt ggcagatatt acatctaaat cacttggttc
    57541 taacactcca atcaacattg ttcgtgcaac tgttgaaggt ttgaaacaat tgaaacgcgc
    57601 tgaagaaatt gctgcccttc gtggtatttc agtttctgat ttggcataag aaaggggata
    57661 aaatggctca aattaaaatt actttgacta agtctccaat cggacgcatt ccatcacaac
    57721 gtaaaactgt tgtagcactt ggacttggca aattgaacag ctctgttatt aaagaagata
    57781 acgctgctat ccgtggtatg attacagcag tatctcactt agtaacagtt gaagaagtaa
    57841 actaatgaag ttttagggga tgtgcactgt accatcccct aaaactagat atagtcatct
    57901 atgatgacat cgtataggcg agttgatggg ggagacaacc ttttctccct tatcggcgct
    57961 agcattttac aaaagaggag aaaataaaaa tgaaacttca tgaattgaaa cctgcagaag
    58021 gttctcgtaa agtacgtaac cgcgttggtc gtggtacttc atcaggtaac ggtaaaacat
    58081 ctggtcgtgg tcaaaaaggt caaaaagctc gtagcggtgg cggagttcgc cttggttttg
    58141 aaggtggaca aactccattg ttccgtcgtc ttccaaaacg tggattcact aacatcaacg
    58201 ctaaagaata cgcaattgtg aaccttgacc aattgaacgt ctttgaagat ggtgctgaag
    58261 taactccagt tgttcttatc gaagcaggaa ttgttaaagc tgaaaagtca ggtattaaaa
    58321 ttcttggtaa cggtgagttg actaagaaat tgactgtgaa agcagctaaa ttctctaaat
    58381 cagctgaaga agctatcact gctaaaggtg gttcagtaga agtcatctaa gagaggtgac
    58441 ctatgttttt taaattatta agagaagctc ttaaagtcaa gcaggttcga tcaaaaattt
    58501 tatttacaat ttttatcgtt ttggtctttc gtatcggaac tagcattaca gttcctggtg
    58561 tgaatgccaa tagcttgaat gctttaagtg gattatcctt cttaaacatg ttgagcttgg
    58621 tgtcggggaa tgccctaaaa aacttttcga tttttgccct aggagttagt ccctatatca
    58681 ccgcttctat tgttgtccaa ctcttgcaaa tggatatttt acccaagttt gtagagtggg
    58741 gtaaacaagg ggaagtaggt cgaagaaaat tgaatcaagc tactcgttat attgctctag
    58801 ttctcgcttt tgtgcaatct atcgggatta cagctggttt taataccttg gctggagctc
    58861 aattgattaa aactgcttta actccacaag tttttctgac gattggtatc atcttaacag
    58921 ctggtagtat gattgtcact tggttgggtg agcaaattac agataaggga tacggaaacg
    58981 gtgtttccat gattatcttt gccgggattg tttcttcaat tccagagatg attcagggca
    59041 tctatgtgga ctactttgtg aacgtcccaa gtagccgtat cacttcatct atcattttcg
    59101 taatcatttt gattattact gtattgttga ttatttactt tacaacttat gttcaacaag
    59161 cagaatacaa aattccaatc caatatacta aggttgcaca aggtgctcca tctagctctt
    59221 accttccgtt aaaggtaaac cctgctggag ttatccctgt tatctttgcc agttcgatta
    59281 ctgcagcgcc tgcggctatt cttcagtttt tgagtgccac aggtcatgat tgggcttggg
    59341 taagggtagc acaagagatg ttggcaacta cttctccaac tggtattgcc atgtatgctt
    59401 tgttgattat tctctttaca ttcttctata cgtttgtaca gattaatcct gaaaaagcag
    59461 cagagagcct acaaaagagt ggtgcctata tccatggagt tcgtcctggt aaaggtacag
    59521 aagaatatat gtctaaactt cttcgtcgtc ttgcaactgt tggttccctc ttccttggtg
    59581 tgatttccat tttaccgatt gcagctaaag atgtatttgg tctttctgat gttgttgcct
    59641 ttggtggaac aagtctcttg atcattatct ctacaggtat cgaaggaatc aagcaattgg
    59701 aaggttacct attgaaacgt aagtatgttg gttttatgga cagaacagaa taaaagtatt
    59761 tactgaatca gtaaatgctg agagagtgga ggtttaaact ctgacatttg taagagttgg
    59821 atctcccctc ttctattttg tttttaaata ggggtgaaaa gactttttgc ttctatttaa
    59881 aaataaaata aggagatcaa atcatgaatc ttttgattat gggcttacct ggtgcaggta
    59941 agggaactca agcagcaaaa atcgtagaac aattccatgt tgcacatatc tcaacaggtg
    60001 atatgttccg cgctgcaatg gcaaatcaaa ctgaaatggg tgttcttgct aagtcatata
    60061 ttgacaaggg tgaattggtt cctgacgaag ttacaaatgg aatcgtaaaa gaacgtcttt
    60121 cacaagatga tattaaagaa acaggattct tattggatgg ttacccacgt acaattgaac
    60181 aagctcatgc cttggacaaa acattggctg aacttggcat tgaactagaa ggtgttatca
    60241 atattgaagt gaaccctgac agccttttgg aacgtttgag tgggcgtatc atccaccgcg
    60301 taactggaga aactttccac aaggtcttta acccaccagt tgactataaa gaagaagatt
    60361 actaccaacg tgaagatgat aagcctgaga cagtaaaacg tcgtttggat gttaatattg
    60421 ctcaaggaga accaatcatt gctcactacc gtgccaaagg tttggttcat gacatcgaag
    60481 gtaatcaaaa tatcaatgat gtcttctcag atattgaaaa agtattgaca aatttgaaat
    60541 aaagcgtttt tcacacttgc aaaaatccgc tacaaatgtt atactgagat agtctgactt
    60601 ataattgttg tctctgtgtc tagaggcatc gaatcgaaat ttatggaggt gcttttgcgt
    60661 ggcaaaagac gatgtgattg aagttgaagg caaagtagtt gatacaatgc cgaatgcaat
    60721 gtttacggtt gaacttgaaa atggacatca gattttagca acagtttctg gtaaaattcg
    60781 taaaaactat attcgtattt tagcgggaga tcgtgttact gtcgaaatga gtccatatga
    60841 cttgacacgt ggacgtatca cttaccgctt taaataatcg aaaaacttgg agggataaga
    60901 aatgaaagta agaccatcgg tcaaaccaat ttgcgaatac tgtaaagtta ttcgtcgtaa
    60961 tggtcgtgtt atggtaattt gcccagcaaa tccaaaacac aaacaacgtc aaggataaga
    61021 tagaaaggag aaaacatggc tcgtattgct ggagttgata ttccaaatga caaacgcgta
    61081 gtaatctcat tgacttatgt ttatggtatc ggacttgcaa catctaagaa aattttggct
    61141 gctgctggaa tctcagaaga tgttcgtgta cgtgatctta catcagatca agaagatgct
    61201 atccgtcgtg aagtggatgc aatcaaagtt gaaggtgacc ttcgtcgtga agtaaacttg
    61261 aacatcaaac gtttgatgga aatcggttca taccgtggta tccgtcaccg tcgtggactt
    61321 cctgtccgtg gacaaaacac taaaaacaac gctcgcactc gtaaaggtaa agctgttgcg
    61381 attgctggta agaaaaaata atataggagg taaaagtctt ggctaaacca acacgtaaac
    61441 gtcgtgtgaa aaagaatatc gaatctggta ttgctcatat tcacgctaca tttaataaca
    61501 ctattgttat gattactgat gtgcatggta atgcaattgc ttggtcatca gctggtgctc
    61561 ttggtttcaa aggttctcgt aaatctacac cattcgctgc tcaaatggct tctgaagctg
    61621 ctgctaaatc tgcacaagaa cacggtctta aatcagttga agttactgta aaaggtccag
    61681 gttctggtcg tgagtcagct attcgtgcgc ttgctgccgc tggtcttgaa gtaacagcaa
    61741 ttcgtgatgt gactccagtg ccacacaatg gtgctcgtcc tccaaaacgt cgccgtgtat
    61801 aatcatcgca ttacactgct tttcgtttaa gagggagtaa ctaaatgatc gagtttgaaa
    61861 aaccaaatat aacaaaaatt gatgaaaata aagattatgg caagtttgta atcgaaccac
    61921 ttgaacgtgg ctacggtaca actcttggta actctcttcg tcgtgtactt ctagcttctc
    61981 taccaggagc agctgtgaca tctatcaaca ttgatggtgt gttacatgag tttgacacag
    62041 ttccaggtgt tcgtgaagac gtgatgcaaa tcattctgaa cattaaagga attgcagtga
    62101 aatcgtacgt tgaagacgaa aaaatcatcg aactggatgt tgaaggtcct gctgaagtaa
    62161 cagctggtga cattttgaca gatagcgata ttgaaattgt aaatccagat cattatctct
    62221 ttacaatcgg tgaaggttct tctctaaaag cgactatgac tgttaacagt ggtcgtggat
    62281 atgtacctgc tgatgaaaat aaaaaggata atgcaccagt tggaacactt gctgtagatt
    62341 ctatttatac accagttaca aaagtcaact atcaagtgga acctgctcgt gtaggtagca
    62401 atgatggttt cgacaaatta acccttgaaa tcttgacaaa tggaacaatt attccagaag
    62461 atgctttagg gctttcagca cgtattttga cagaacatct tgatttgttt acaaatctta
    62521 ctgagattgc taagtcaact gaagtgatga aagaagctga tactgaatct gacgaccgta
    62581 ttttagatcg tacgattgag gaactggact tgtctgtgcg ttcatacaac tgtttaaaac
    62641 gtgccggtat caatactgtg catgatttga cagaaaaatc tgaagcagag atgatgaaag
    62701 tacgaaatct tggacgcaag agtttggaag aagtgaaact caaactcatt gatttgggtc
    62761 ttggattaaa agataaataa aggaggaata catggcttac cgtaaactag gacgcactag
    62821 ctcacaacgt aaagcaatgc ttcgcgattt gacaactgac cttttgatca acgaatcaat
    62881 cgtgacaact gaagctcgtg ctaaagagat ccgtaaaact gttgaaaaaa tgattactct
    62941 aggtaaacgt ggtgatttgc atgcacgtcg tcaagcagct gctttcgtac gtaatgaaat
    63001 cgcatctgaa aactatgatg aagcaactga taagtacact tctactacag cacttcaaaa
    63061 attgttctca gaaatcgcac ctcgttatgc tgaacgtaac ggtggataca ctcgtatcct
    63121 taaaactgaa ccacgtcgtg gtgatgcagc gccaatggcg atcatcgaat tagtataaaa
    63181 tcatcaattt tgttgagtgt tatgatgatg gagtcttgtg ctcttagtct agctctggtc
    63241 taccgctagg atttcggtcc tagcgggaac actcatcata agttgggata gtagacgctt
    63301 gtttacgaaa ttgttttttt cttaagaaca acttcgtaag caggcgtttt tgagtatttt
    63361 cgttagaatt atgctatact atttgaaaag aatcctgttt aatgttaagg tttcttattt
    63421 taagaagaat tggagtttac ttatgaaagc cattataact gttgttggta aagataaatc
    63481 tggaattgtt gcaggtgttt ctggtaaaat tgcagaatta ggattgaata ttgacgatat
    63541 ctctcaaact gtcttggatg aatattttac gatgatggct gttgtatcta gtgatgaaaa
    63601 gcaagatttt acctatcttc gtaatgaatt tgaagctttt gggcaaactt tgaatgtaaa
    63661 aatcaatatt cagagtgcag cgattttcga agctatgtat aatatctagg aggtcatcat
    63721 ggatattaga caagttactg aaaccatcgc catgattgag gagcaaaact tcgatattag
    63781 aaccattacc atggggattt ctcttttgga ctgtatcgat ccagatatca atcgtgctgc
    63841 ggagaaaatc tatcaaaaaa ttacgacaaa ggcggctaat ttagtagctg ttggtgatga
    63901 aattgcggct gagttgggaa ttcctatcgt taataagcgt gtatcggtga cacctatttc
    63961 tctgattggg gcagcgacag atgcgacgga ctacgtggtt ctggcaaaag cgcttgataa
    64021 ggctgcgaaa gagattggtg tggactttat tggtggtttt tctgccttag tacaaaaagg
    64081 ttatcaaaag ggagatgaga ttctcatcaa ttccattcct cgcgctttgg ctgagacgga
    64141 taaggtctgc tcgtcagtca atatcggctc aaccaagtct ggtattaata tgacggctgt
    64201 ggcagatatg ggacgaatta tcaaggaaac agcaaatctt tcagatatgg gagtggccaa
    64261 gttggttgta ttcgctaatg ctgttgagga caatccattt atggagggtg cctttcatgg
    64321 tgttggggaa gcagatgtta tcatcaatgt cggagtttct ggtcctggtg ttgtgaaacg
    64381 tgctttggaa aaagttcgtg gacagagctt tgatgtagta gccgaaacag ttaagaaaac
    64441 tgcctttaaa atcactcgta tcggtcaatt ggttggtcaa atggccagtg agagactggg
    64501 tgtggagttt ggtattgtgg acttgagttt ggcaccaacc cctgcggttg gagactctgt
    64561 ggcacgtgtc cttgaggaaa tggggctaga aacagttggc acgcatggaa cgacggctgc
    64621 cttggccctc ttgaacgacc aagttaaaaa gggtggagtg atggcctgca accaagtcgg
    64681 tggtttatct ggtgccttta tccctgtttc tgaggatgaa ggaatgattg ctgcagtgca
    64741 aaatggctct cttaatttag aaaaactaga agctatgacg gctatctgtt ctgttggatt
    64801 ggatatgatt gccatcccag aagatacgcc tgctgaaacc attgcggcta tgattgcgga
    64861 tgaagcagca atcggtgtta tcaacatgaa aacaacagct gttcgtatca ttcccaaagg
    64921 aaaagaaggc gatatgattg agtttggtgg tctattagga actgcacccg ttatgaaggt
    64981 taatggggct tcgtctgtcg acttcatctc tcgcggtgga caaatcccag caccaattca
    65041 tagttttaaa aattaagaaa ataggagaaa ttttaagttc tatttaagat tagatgtgta
    65101 tactataatc attaaataaa gacctcctaa tattatttga aacagataac actgaattag
    65161 tttgaatttg attttcatct aatatcttta tttaatgaac tcctaaactt tttcataata
    65221 atctccttca aaagtcgcct gtatgggtgg cttttatttt atcattcatg atataataga
    65281 agcaaacgga ggacggaaaa tggtaaaagt acgattgtat ttggtacgtc atggcaagac
    65341 catgtttaac acgattggtc gcgcgcaagg ttggagcgat actcccttaa ctgctgaagg
    65401 tgaacgaggg attcaagagt taggaatcgg tttgcgagaa tctgatctac agtttgagcg
    65461 cgcttattcg agtgattctg gtcgtaccat tcagaccatg ggaattatac ttgaagaact
    65521 tggcttgcag gggaaaatcc cttatcgcat ggacaagcgt atcagagaat ggtgtttcgg
    65581 tagttttgat ggagcctatg atggcgatct tttcatgggc attattcctc gtatctttaa
    65641 tgtggaccac gttcaccaat tgtcttatgc tgaactggct gagggcttgg tagaggtcga
    65701 tacagctggt tgggctgaag gttgggaaaa actcagtggc cgaatcaagg aaggctttga
    65761 aataattgca aaagaaatgg aagatcaagg tggaggtaac gcccttgttg tcagccatgg
    65821 aatgactatt ggaaccattg tttatctgat taatggcatg catccgcatg gtctagataa
    65881 tggtagcgtg acgattcttg aatatgagga cggtcagttt agggttgaag ttgtcggtga
    65941 ccgtagttac cgagagctag gacgtgagaa gatggaagaa ggctctattt aatcagtcta
    66001 gacttgcttg ccatgagcta gggatttgat aagaatatca agataagaaa aaacagccga
    66061 gggtactcct ttcggctgtt tttgatgtgg aaaactaaag tgtaatgcta ttgcttttag
    66121 agattttcat aaacaagagc aaggaaccta ctgttagaac agtcaggata gttgacaagg
    66181 ctgcggctac accgtaattt cctctgagaa cctctgtata aatagctaca gtcattgttc
    66241 ttgttttgac attgtagagg aggatagagg atagaagtag agagttctga aatcagtgtg
    66301 acccaagata ggatggctcc agaaataata cccgatagca tcattggagt tgtaatctta
    66361 gcaaaggtat tgagacgact acttcctaag ctttcagcag cttcttcaat acttggtgct
    66421 atttgttgta agctagcaac agatgagcga atagtatacg gtaatcttct gacagataga
    66481 gacataatca agatgaaagc agtccctgta atcataagaa atccacttcc aaatagacca
    66541 gtattgaagg aagaaatgaa ggcaatccct agaacggttc ctggtacaat ataaggtacc
    66601 atactgaggc tgtcaattaa gtttgtaaac aaattccgtt ttctaacggc taggtaggag
    66661 ataaatgtcg caaatagaac aactagaact aaggcaatca aagggatacg aatggtattg
    66721 aaaatagcag atcccatacg attgaaagct agcttgtaac tgtttggaga ataaccttta
    66781 aaaaatacca tacctgatgt ttttaggaaa gaggtataaa ttaagtagat ttgaggtaaa
    66841 acagagataa agataattcc gtagactgtt gcataaatgg cagccatttt tccttttgta
    66901 gtttttttag gctcaattgg atggagcaga ttcatgctga aactgtagcg gtttgcaatg
    66961 tgtttttgga taaggaaaat tgccaaggca atgataatcg ccataattgc aaaagcagaa
    67021 tttcctccaa cctcgctaat aaattgggta taaatcagga cagggaaagt ccgatatcct
    67081 tcgccaatca acataggcgt tccaaagtct gagaatgctc tcataaatac aagcaaggag
    67141 ctgctagtaa ggttggaact agaagaggta aaacaaccgt tacgataggt ttaaatccga
    67201 aggaccccat gctttcagct gcttcaagta gagaattgtc aatactgttc attgttccag
    67261 caacatatag aaataccagt gggaatagtt gcagtgtaaa gacaagtaca attcctttga
    67321 atccataaat atcgatagct ggaagatgaa gggcatttgt caaaaattta gtgatgaccc
    67381 catttcgtcc cagcaagaga acccaggagt aggctcctac gaaaggagct gacatggaag
    67441 caatgataat caatatttgt agaaatttct tccccttgaa gtcatacata gagaagagat
    67501 aagctaatag ggttcctaca actaaggaag tgacagtagc ggtaatggaa accctgaaac
    67561 tgttgactag tgtctcagag tagtaggctt tactaaagaa agtgacaaaa ttagctagtg
    67621 agaattgtcc ttcatgtata agtgcttgct tgagcacggt aatgatagga taaacgagaa
    67681 agacaagata ggtaagaaag aggaagaaag aggaggctgt ccaaatattt agttttttac
    67741 gttccatggt tgactccttt tatcaggttt tgggaaccat ctgcagaaaa gatgtttaat
    67801 ttttgcgtat tgattcgtag acgaatacga ttgccttttt gtagttcttc ttcaaaagtt
    67861 gattcttcac taacttgaat ttttgaggca aaacctgtct caatgaaata ctccgtattt
    67921 agtccaagat agacgctatc gctaatagtt ccttcaatat ctccagattc atctttgata
    67981 aactcttcgg gacgaatgct tacatgaata gcttgctcct caacctgatc aagagctggc
    68041 attcgaaggg catagccatc tgaaaagacg atataagcgc cgtcgctccg tttttcaaga
    68101 ttggcaggga taatatttgt gcgtccgata aaggttgcca caaactcatt agctggttta
    68161 tgatagagtt cttttggtcg gccgatttgt tggatcaccc catctttcat aacagcaatt
    68221 tgatctgaaa tagccatggc ttcttcttgg tcgtgggtta cataaacagt tgtaattccc
    68281 acttcgtgtt ggatttctcg gatggcttga cgcatatcca agcgaagttt ggcctccaga
    68341 ttactaagtg gctcgtccat gaggagaaca cttggattaa ccgctaaggc gcatgccaag
    68401 gtgacacgtt gttgttgtcc accactgagt ttatcgggct ttcgatccgc atattgagca
    68461 atttgcatga gttcaagata cttgttggtc tgttgaatca attcttcttt tggaaccttc
    68521 ttttgcttaa gaccaaaagc aacgttgtct cggacagtca aatgtgggaa aatagcgtag
    68581 ttttggaaaa ccatcccgat attgcgtttg ctgggttcca tattattgat ttttgtatca
    68641 tcgaagtaaa attctccatc tttgatactg ttgaaacctg caatcatacg aagaagggtc
    68701 gttttcccac atcctgaagg tccaagaagg gtaaagagac ttccttttgg aattgtaatg
    68761 ttcaaattct caataacagg gacatcgtgg tagatttttt ggcgttaata attttgatct
    68821 cactcatagt gaaccttttt tactgtttag attggatatc tgtaaagact tcgttgtatt
    68881 tcttaacgat atctgattta ttcttgatga cataatcata atcttcagtg agtgttttga
    68941 ttttgtcaat tggtttcatg ttttcgcttg ttttagcatt tttacgaaca ggacggttag
    69001 tagtggttgt accaagtgta tcttgtactt cttgagagat aataaaatcg ataaatttct
    69061 tgtcattttc catattttta gcttttttaa cgatagcagc actagcaggt aggaagacgg
    69121 ttccttcttt tggatagact actttaatgt tagctccgtc atttaagagt ttaactgctg
    69181 gatcctcata agagagacca acagccattt ctccatcaac gactgcttta tagacaccag
    69241 atgaacttga accgatttta tagtgtattg aaactagaat agtacacctc tacttctaaa
    69301 acattgttag aaatcgattt gactgtcctg attaatttgt cctgttctta tttcatttca
    69361 ctatgccatc aataagtgtg aaaagatctt ttacataaga ccaagcctta tcatctttgt
    69421 aaccaccttg agcttgtagc atatttgtta attgagcaaa ggcgctagaa gagtttgctg
    69481 ggtcagcagt tgcgattttt tcttttagtt caggtttgag aagatcgtta tatccttcga
    69541 tgttcatgcc tttagttaaa tcagggtgga cgattaaaac actaccatct agtgtataag
    69601 gagtagagaa gccagttgtg ttttgatatt ctttgataac attatcattt tcttttgaag
    69661 tatagttttc aaagagttct ccgtgggtag tatattgtgt ataagaacca ccaaagataa
    69721 catcagctac aggaacttct ttttctgact ctagtttttt gaaaagttct ccagtaccag
    69781 cttgaatcag ttctactttg ataccatatt tttcttcaaa ggcaggaata gttgctccaa
    69841 ttaagccctc tgagtttggt gaataaacga ctagcgaacc gccgtctcct ttatcagatg
    69901 aactgtcatc ggcagattca ttagaagaac aagcagcata atacatccat ttctttttca
    69961 tgatggatac ctccgttgtg ttatttaagt ttattttaaa acaatgtaag cgtttttaaa
    70021 acatacaatt ctattctata gtgtattgaa tctataacag tacactttga ctgctaaaat
    70081 atttctataa attaatttga ctttcctgat agagatgttc acatcttatt tcaattcact
    70141 atattagagt aaaattctct acaaaaagaa gaatagccta ttttactatt cttctgagtg
    70201 atttcaattc ctttggggaa atatggagat actttttaaa tcctgacaaa tggttgtttc
    70261 tttttctaaa tcggtgatac tgtatcggag aatgcgcgtg aggtcacaaa ggctgcgata
    70321 gagcttctat ggagaatttc tttttggaga gattttttaa aggaatgaga catccgctac
    70381 ctccttggaa ggtttttttg tgataagtat agcagtttaa aaattctaga gcaaggtaaa
    70441 atagaaaagg tttggctaaa attttttagc taaacctttt gaaaagttaa gtatgtatta
    70501 tagatgcttg ttatctgcaa atagctagag catttcaagg aaataaacta gaaataacaa
    70561 ttaatatggt ggttcagaaa taccttttga taatcaataa gatcttcagg atgaagtgcg
    70621 ttgattccat ccatttcata tttccgattt aataaacgat atttgttttc accaaattga
    70681 tgaaaaggga gtagttgaac ttggtcgata tttaatgagt taaatagagt agcgaatttt
    70741 tctgcatcct ctaaactatt gttaaaatta ggaataactg ggattcttaa aacgatagtt
    70801 ttattttgtg aaaaagcata atgaatgttt ttaataatca tttgattaaa aaccccagtc
    70861 acttttttat gttttataga attataatgt tttaggtctg tgtagataaa atccacatat
    70921 tgaattaaat caataaattt ttcatgatca acaaaggcag tagtttcaat ggcagtgtgt
    70981 atgtgatgtt ctttagctga ttttaagatg gctttagcaa attcaaactg agcaaatatt
    71041 tcacctcctg ataaagttaa acctccaccg gattcttcgt aaaattcttt gtcttttaat
    71101 acctctgtaa taatttcttc tacagtcttt tcttcaccga ctaaggtgaa tttctctcgt
    71161 tgagcatctt tcattttttc aggtttcatt ctttgagatt caggattaga acaccatgga
    71221 cagcgcagag gacatccttt taaaaaaaca gttgtacgaa tacccgggcc gtcatgaatt
    71281 gaaaagtgtt gaatattaaa aataattcct ttagatattt ccataagagt tcctcctctt
    71341 cataagtcta tcctatcaca aaaacgaaag aaaaacaatt acgaacgaaa ggttaattta
    71401 ttgttttttg ctttttattt tggtagaata aaacggaggt gtaaaatgaa aagattggaa
    71461 caaattatta aattagtatc agaatatgaa aagatcgacg ttaatacatt atcggaaaaa
    71521 ttaaatgtat cgaaagtaac gattagaaaa gatttagata aattagagtc aaaaggttta
    71581 ttacacagag agcatggata tgctgtatta aatagtggag atgacttaaa tgtacgtttg
    71641 tcaattaatt atgaaattaa gagaaaaatt gttcaggaag cagtaaaatt ggtgtcagat
    71701 aatgaaacaa taatgataga atctggatcg acctgtgctt tacttgctga ggaaatttgc
    71761 aagcaaaaaa gaaatgttac gattgtaaca aattcatttt ttatagcaaa ttttgtgaga
    71821 gcttatgatt catgtcgtat tattgttctt ggtggagagt ttcagaagga ttcacaggtt
    71881 actgtgggac ctttattaaa agaaatgata cagacttttc atgtgcatca agcttttgtt
    71941 gggacagatg gttacgataa agagatgggc tttacaggaa aagatttaat gcgcagtgag
    72001 gtagttcaat atatttcagc agcgtcggat aaagtcattg tactaactga ctcaagtaaa
    72061 tttgataaaa ggggtacagt aagaagattt gctttaagtc aagtctatga agtaataaca
    72121 gacgaaaaac tttctaaaca aaatatagct acattagaaa atgctgggat aatggttaag
    72181 gtagtttcgt aagaggttaa gtgtatgaat caagatagga ataaactgct ctctaaaatt
    72241 gcttatctgt attatattga aaacttaaat cagtcacaaa tagcagcaaa attaggaatt
    72301 tatagaacct ctattagtag aatgttaaca gaagcaagga atgcaggaat tgttaaaatt
    72361 gaaatagaga attttgatac caatatgttt aagttggaaa attatgtaaa agaaaaatat
    72421 ggtctggaaa gtttagaaat tattccaaat gaatttgatg ataatccaac aattttatct
    72481 gaaagaattt ctcaagttgc agcaggtgtc cttaggaatc taattgatga taatatgaaa
    72541 attggctttt cttgggggaa aagtttaagt aatttagtag atttaattca cagtaaaagt
    72601 gtccgaaatg ttcacttcta tcctctagca ggtggtccta gtcacataca cgctaaatac
    72661 catgtgaata cactgattta tgaaatgtct agaaaatttc atggagagtg tacatttatg
    72721 aatgcaacga ttgtgcaaga aaataaattg ttagcagatg gtattttgca atcaagatat
    72781 tttgaaaatt tgaaaaatag ttggaaagat ttagatatag ctgtagtcgg aattggtgat
    72841 tttagcaata aaggaaagca tcaatggtta gacatgctta cagaggatga ctttaaagaa
    72901 ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat tttttgattc aaaaggtaaa
    72961 gaagtctatg aaaacttaca ggaaagaacg atagcaatct ctttggaaga tttaaaaaat
    73021 attcctcaaa gtttagctgt tgcttacggt gatacgaaag tatcttcgat tctttctgtc
    73081 ttgcgtgcta atttagtaaa tcatttgatt acagacaaaa atacaatttt aaaagttttg
    73141 gaagaagatg gggatttgac ttttagagag attctaggtg agtgaaaatg atagactgat
    73201 tcagtttatc atttttcttt ttagttgatt gcacatttgt gcttatataa acaaaaatag
    73261 tttatctgtt gtttttggat tgacaacttt attatgtagt tgtattctat agttacaaaa
    73321 gaaaatttta aaatttcaaa tgaaaaaagc tttttacata gtgaaatgag gaggaattta
    73381 tggaaattat tgttccagat caaattatca tgggtttaat tttatatgct ggcgatgcga
    73441 aacaacatat ttataaagca ttagattaca taaagaacgg tacatgtgaa cgatgtgaag
    73501 aagaaatcca gttagctgat gcagccttat tagaagctca taatctacaa acaaaattct
    73561 tggcacagga agcgtctggt acaaagacag aaattacagc tctctttgtt cattcacaag
    73621 atcatctcat gactagtatg acggagatta atttaatcaa agaaattatt agtttgagaa
    73681 aagaacttca taaaaaataa tactagagta ttatcattgt tattaacata gaggaggaaa
    73741 acataatggt gaagattggt ttgttttgtg cagcaggttt ttctactggt atgcttgtaa
    73801 ataatatgaa aattgcagcg caatctagtg gagttgaggc agaaatagag gcgttttctc
    73861 agtctaaatt agcggattat gcgccaaata tagatgttgc actattgggt ccacaagttg
    73921 cttatacatt agataaatca aaagaaattt gtgataagtg tgatgttccg atagctgtta
    73981 ttccgatgat ggactatggt atgttagatg ggaaaaaagt attagatttg gccctatctt
    74041 tgattagtgg gtaagaaaag gagatttatt atgtcaaaga tggatgttca gaaaatcatt
    74101 gcaccgatga tgaagtttgt gaatatgcgt ggcattatag ctctaaaaga tgggatgtta
    74161 gcaattttgc cattgacagt agttggtagt ttgttcttga ttatgggaca attgccgttc
    74221 gaaggattaa ataagagcat tgctagtgtt tttggagcta attggacaga gccgtttatg
    74281 caagtatatt caggaacttt tgctattatg ggtctaattt cttgtttttc aattgcctat
    74341 tcttatgcta agaatagcgg agtagaggct ttaccagctg gagttctatc tgtatctgca
    74401 ttctttattt tgctaagatc atcttatatc cctaaacaag gtgaggcgat tggggacgct
    74461 attagtaaag tttggtttgg aggccaagga attatcggtg ctatcattat aggtttggta
    74521 gtaggaagta tttatacctt ctttataaag agaaaaattg ttattaagat gccagaacaa
    74581 gttccacaag ctattgcgaa acagtttgaa gcaatgattc cagcatttgt aattttctta
    74641 tcttctatga ttgtatatat tttagcgaag tcattgacta atggcggaac attcatagaa
    74701 atgatttatt ctgctattca agttccgttg caaggtttaa ctggatcttt gtatggtgct
    74761 attggaattg cattctttat atcatttttg tggtggtttg gtgttcatgg gcaatcggta
    74821 gtaaatggag tagtgacagc tctgctttta tctaatcttg atgctaataa agctatgtta
    74881 gcctctggta atctatcatt agaaaatggt gcacatattg ttactcaaca atttttagat
    74941 tcatttttaa ttctatcagg ttcagggatt acgtttggtc ttgtagttgc catgcttttt
    75001 gcagcaaaat caaaacaata ccaagcctta ggaaaagttg cagcttttcc agcaatattt
    75061 aacgtaaatg agccagttgt atttggattt ccgattgtca tgaatccagt tatgtttgta
    75121 cctttcattc ttgttcctgt acttgcagct gtgatagtat atggagctat tgcaacaggt
    75181 ttcatgcagc cattctcagg ggtaacattg ccttggagta caccagctat tctatcagga
    75241 tttttggtgg gtggatggca aggtgttgtg actcagttat tagtattggt gatatctaca
    75301 gtggtttact ttccattctt taagatacaa gatcgtttag cttaccaaaa tgaaatcaaa
    75361 caatcttaga ggtatttgtg tgttactgtt aaactcacac atttgtgcta aaaattagag
    75421 agttaaaatt tttctagtta aaagcttgaa aatttctata aaaatcggta ttatattttc
    75481 gaaagaaata aaaatatttt cgaaagaaag gtgcttacga tggtaaatac agaagtagca
    75541 agaacaacaa tcaagacaga atattttggc agccttactg aaaggatgaa caaatatcga
    75601 gaagatgttt taaataaaaa accttatatt gatgctgaga gagcagttct agcaacacgc
    75661 gcctatgaac gatacaagga acaacctaat gtcctaaaac gtgcatatat gctgaaagaa
    75721 attttggaaa atatgtctat ctatattgaa gaagaatcta tgattgcggg aaatcaagct
    75781 tcttccaata aagatgctcc tatttttccg gaatatacgc tagaatttgt tctcaatgag
    75841 ttagatcttt ttgaaaagcg tgatggagat gttttctata ttacagaaga aacaaaagaa
    75901 caacttagaa gtattgctcc gttttgggaa aataataatt tacgtgctag agctggtgcc
    75961 ttattacctg aagaagtgtc tgtttatatg gaaacaggat tcttcggtat ggaaggtaag
    76021 atgaattctg gagatgctca cttagcagtt aactatcaga aacttttgca atttggttta
    76081 agaggttttg aagagcgggc tcgtaaagca aaagtagctc tagatttaac agatccagca
    76141 agtattgata aatatcattt ttacgactct atatttatcg taatcgatgc tattaaagta
    76201 tatgcaaagc gctttgttgc tcttgctaaa agtttagccg aaaatgcaaa tcctaaacgt
    76261 aagaaagaat tacttgagat tgcagatatt tgctctagag tcccatatga accggcaact
    76321 acttttgcag aagctattca atcagtttgg tttattcaat gtattttaca aattgaatct
    76381 aatggccact ctctttcata tggccgtttt gatcaatata tgtatccata tatgaaggct
    76441 gatttagaaa gtggtaaaga aacagaagat agcattgttg aacgtctgac aaatctttgg
    76501 attaagacaa ttacaattaa taaggttcgc agtcaatcac atacattttc ttcagcagga
    76561 agtcctttat atcaaaatgt tacaattggt ggacagactc gagataagaa ggatgctgtt
    76621 aacccattat cttatttggt attaaaatca gttgcacaaa cccatctacc gcaacctaat
    76681 ctaactgtac gttaccatgc aggtttagat gctcgtttca tgaatgagtg tattgaagtg
    76741 atgaaacttg gttttggtat gcctgcattt aataatgatg agattattat tccttctttt
    76801 attgcaaaag gagtattgga agatgatgct tatgattaca gtgccattgg atgtgttgaa
    76861 acggcagttc cagggaaatg gggctatcgt tgcacaggta tgagttatat gaacttccct
    76921 aaggttctac ttatcacgat gaatgatgga attgatccgg cttcgggtaa acggtttgca
    76981 ccaagctttg gtcattttaa ggatatgaag aacttttctg aattagaaaa tgcttgggat
    77041 aaaacactaa gatatttgac acgaatgagt gttattgttg aaaattctat tgatttatca
    77101 ttggaacgag aagttcctga tattctatgt tcagcattga ctgatgattg tattggtcgt
    77161 ggaaaacacc ttaaagaagg tggagcagta tatgattata tatcaggatt gcaagttgga
    77221 attgcaaatt tgtcggattc gttagctgca attaaaaaat tggtgtttga ggaagaacgt
    77281 ataagcccaa gtcaactttg gcatgcactg gaaacagatt atgccggaga agaaggtaag
    77341 gtcattcaag aaatgttgat tcatgatgca cctaagtatg gtaatgatga tgattatgct
    77401 gacaaattgg ttactgctgc ttatgacatt tatgttgatg aaattgctaa atatcctaat
    77461 acacgttatg gaagagggcc tattggagga attcgttatt caggaacatc ttctatatca
    77521 gccaacgtag ggcagggacg tggaacatta gcaactccag atggacgcaa cgcgggtaca
    77581 ccgttagcag agggttgttc accatcacat aatatggatc aacacggccc tacatctgtt
    77641 ttaaaatctg tttcaaaatt accaacagat gaaatcgtag gtggggttct cttaaatcag
    77701 aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat taaaactaat tgctttgtta
    77761 cgaacattct ttaatcgttt acatgggtac catattcaat acaatgttgt ttccagagag
    77821 acgttgattg acgctcagaa acatcctgaa aaacacagag acttaattgt tcgtgttgca
    77881 ggatactctg cattcttcaa tgttctttct aaggcaaccc aagatgacat tataggacgt
    77941 actgagcata ctttgtaaaa taaagaggtt ctttttatgg aatttatgct tgacacatta
    78001 aatttagatg agattaaaaa gtggtctgaa attttgccgc tagctggggt aacttcaaat
    78061 cccactattg caaaaagaga gggttctatt aatttttttg aacgaatcaa agatgtaaga
    78121 gaattgattg gctctacacc ctctattcat gttcaggtga tttctcaaga ttttgaaggc
    78181 atcttaaagg atgctcatga aattcgaaga caagcaggag atgatatatt tatcaaagta
    78241 cctgttactc cagctggatt acgtgcaata aaggtgctaa aaaaagaggg ctaccatatc
    78301 actgcaacag ctatttatac agttattcag ggattattag ctatcgaagt aggagcggat
    78361 tacctagctc catattataa tagaatggaa aatctgaaca ttgattcaaa ttctgtcatt
    78421 cgtcaattag ctcttgctat tgatagacag aactctccta gtaagatttt agctgcatcc
    78481 tttaaaaatg tagcacaagt aaataatgct ttagctgcag gtgcgcatgc tgttacagca
    78541 ggagcggatg tttttgaatc agctttcgcc atgccatcta tccaaaaggc ggttgatgat
    78601 ttttctgacg attggtttgt tattcaaaat agtcgttcca tttagataga gaggaaatac
    78661 atatgagaat ttttgctagt ccttctagat atattcaggg ggaaaatgcc ttgtttgaaa
    78721 atgccaaatc aattttggat ttgggaaatt gccctattct attatgcgat cagttggttt
    78781 atgatattgt tggaaaacga tttgaagatt acctacatag gtatggtttc catattgttc
    78841 tggcgctatt taatggtgaa gcttctgaca atgaaatcaa tcgagttgtt gccttggctg
    78901 agaaagaaaa ttgtgatagt attatcggtc ttggtggggg aaagacgatt gatagcgcaa
    78961 aagctattgc agatttgatt gaaaagcctg ttattattgc tccaacaatt gcatcgaccg
    79021 acgcacctgt atctgcttta tctgttattt atacagatga aggtgcattt gatcattatc
    79081 tattttattc taaaaatcca gatttagttt tggttgatac aaaagttatt tcacaagccc
    79141 ctaagcgttt attagcgtct ggtattgcag atggtttagc aacttgggtt gaggcgcgtg
    79201 cggttatgca ggcaaatgga aaaactatgt tgggacaaca gcaaacattg gctggagttg
    79261 caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg tttacaggct atggcagctt
    79321 gtgaagctaa agtggtgaca ccagcattag aaaatattgt tgaagctaat actttattga
    79381 gtggtctagg ttttgaaagt ggaggattag ctgcggcgca tgcaattcat aatggtttta
    79441 ctgcattgac aggtgacatt catcatttaa cacatggtga aaaagtagct tatggaactt
    79501 tagtacaact attattggaa aatagaccta aagaagaact tgataagtat attgagtttt
    79561 acaaaaaaat tggtatgcca acaactctaa aagaaatgca tttggatcaa gttggatatg
    79621 atgatttaat aaaagttggt aaacaagcaa ctatggaggg tgagacaatt catcagatgc
    79681 cgtttaagat ttcgccttca gatgttgctc aagctattat cgctgtagat gcctatgtaa
    79741 attcaaaata aacaataagg actactgttt tccaaatggt agtcttttat tgatccctgt
    79801 attgaattct atagaagatt gaaataggat gagaacaaat cgattgggaa agtaaaatta
    79861 atttctataa atgttttagc aattgtttcg tactatttca gattcagtct actatatgtt
    79921 cttcataaat caaaaagcga cataggttgt cggctattta ttgtgaatac attaattagc
    79981 attccagttt tatcttcggt ctaaaataag tattttgtgc tatacgagat aagcttcttg
    80041 acttactcct tgatttactg cataacaatg ggataaaaag tgggagatag agcaattcat
    80101 agtcatcaaa attaatgaga tacagtatac agtttttcct ttaaacacat ttcaaattcc
    80161 ctcaaaaatg gtataatagt aacatcacaa aattggagag agaccatgag tttttacaat
    80221 cataaagaaa ttgagcctaa gtggcagggc tactgggcag aacatcatac atttaagaca
    80281 ggaacagatg catcaaaacc taagttttat gcgcttgata tgttccctta tccgtctgga
    80341 gctggtctgc acgtaggaca cccagaaggt tatactgcaa ccgatatcct cagtcgttac
    80401 aaacgtgcgc aaggctacaa tgtccttcac ccaatgggtt gggatgcttt tggtttgcct
    80461 gcagagcaat acgctatgga tactggtaat gacccagcag aatttacagc ggaaaacatt
    80521 gccaacttca aacgtcaaat taatgcgctt ggattttctt atgactggga tcgtgaagtc
    80581 aacacaacag atccaaacta ctacaagtgg actcaatgga ttttcaccaa gctttacgaa
    80641 aaaggcttgg cctatgaagc tgaagtgcca gtaaactggg ttgaggaatt gggaactgcc
    80701 attgccaatg aagaagtgct tcctgacgga acttctgagc gtggaggcta tccagttgtc
    80761 cgcaaaccaa tgcgccaatg gatgctcaaa atcacggctt acgcagagcg cttgctcaat
    80821 gacttagatg aactagattg gtcagagtct atcaaggata tgcaacgcaa ctggattggt
    80881 aaatcaactg gtgccaatgt aactttcaaa gtaaaaggaa cagacaagga atttacagtc
    80941 tttactactc gtccggacac acttttcggt gcgactttca ctgtcttggc tcctgaacat
    81001 gaattagtag acgctatcac aagttcagag caagcagaag ctgtagcaga ctataaacac
    81061 caagccagcc ttaagtctga cttggctcgt acagaccttg ctaaagaaaa aacaggggtt
    81121 tggactggtg cttatgccat caaccctgtc aatggtaagg aaatgccaat ctggattgca
    81181 gactatgtcc ttgctagtta tggaacaggt gcggttatgg ctgtgcctgc ccacgaccaa
    81241 cgtgactggg aatttgccaa acaatttgac cttccaatcg tcgaagtact tgaaggtgga
    81301 aatgtcgaag aagctgccta cacagaggat ggcctgcatg tcaattcaga cttcctagat
    81361 ggactcaaca aagaagacgc tattgccaag attgtggctt ggttggaaga aaaaggctgt
    81421 ggtcaggaga aggttaccta ccgtctccgc gactggctct ttagccgtca acgttactgg
    81481 ggtgagccaa ttccaatcat tcattgggaa gatggaactt caacagctgt tcctgaaact
    81541 gaattgccgc ttgtcttgcc tgtaaccaag gatatccgtc cttcaggtac tggtgaaagt
    81601 ccactagcta acttgacaga ttggcttgaa gtgactcgtg aagatggtgt caaaggtcgt
    81661 cgtgaaacca acactatgcc acaatgggct ggttcaagct ggtactacct ccgctatatt
    81721 gatccacaca atactgagaa gttggctgat gaggacctcc tcaaacaatg gttgccagta
    81781 gatatctacg tgggtggtgc agagcatgct gttcttcact tgctttacgc tcgtttctgg
    81841 cacaaattcc tctatgacct cgatgttgtt ccgactaagg aaccattcca aaaactcttt
    81901 aaccaaggga tgattttggg aacaagctac cgtgaccacc gtggtgctct tgtggcaacc
    81961 gacaaggttg aaaaacgtga tggttccttc ttccatgtag aaacagggga agagttggag
    82021 caagcgccag ccaagatgtc taaatcgctc aagaacgttg ttaacccaga cgatgtggtg
    82081 gaacaatacg gtgccgatac ccttcgtgtt tatgaaatgt ttatgggacc actcgatgct
    82141 tcgattgctt ggtcagaaga aggtttggaa ggaagccgta agttccttga ccgagtttac
    82201 cgtttgatta caagtaaaga aatccttgcg gaaaacaatg gtgctcttga caaggtttac
    82261 aacgaaacag tcaaagctgt tactgagcaa attgagtctc tcaaattcaa cacagctatt
    82321 gcccaactta tggtctttgt caatgctgct aacaaggaag ataagcttta tgttgactat
    82381 gccaaaggct ttattcaatt gattgcacca tttgcacctc acttggcaga agaactctgg
    82441 caaacagtcg cagaaacagg tgagtcaatc tcttatgtag cttggccaac ttgggacgaa
    82501 agcaaattgg ttgaagatga aattgaaatt gtcgtccaaa tcaaaggaaa agttcgtgcc
    82561 aaactcatgg ttgctaaaga tctatcacgt gaagaattac aagaaatcgc tttagctgat
    82621 gaaaaagtca aagcagaaat tgacggtaag gaaatcgtga aagtaattgc ggtaccgaat
    82681 aaactcgtta atatcgtcgt taaataacga gtttattagc tctatctgcc accttcaata
    82741 gtccactgga ctattgaagc caactaaatt agttaacatt gttgtgaaat aaaaagaagt
    82801 aactctagag tatgaacttt agagttactt ttagaatagg tcagaatgaa tagattagtg
    82861 aacgatagca ggaagtgtga aattttatta tttaagattt ctattattgt agtgtcagtt
    82921 atagtattag taatgtcaat agtgggtgca tattatttta aaaattgtct ttgggacaag
    82981 gaaagtttaa atttgacact cactttagac actctctttg cagtttttat tactttcttt
    83041 agtttttcaa atgataaatc aagcaatatt tttggaatat ctccaaatga aattataagg
    83101 acacagtctg aagtgtatca atttttattt acaaaatctt ttgcaactct attaatagtg
    83161 acaaatttgt tatccattat tcattatttt ggagccaaaa atttaatagt ttcttttaat
    83221 gaaacttatc ctcgtattca atccagtgtt ggtatcatgt ggctaccact gtttggtatt
    83281 ctgataatct attttatttg gctcttaata gagggattaa aatatatcag aaaaataaat
    83341 tatattattc aaaataggga aataatctat ttttattcgc aggtaaaagt tgtagataaa
    83401 cttactgatt ctgaatcgaa aaaatacggt gaatatattg atttgtacga atcgtgtcgt
    83461 cagaacaatt taagtgttct acttaacttt cttcaaaatt cggatgataa acgaggagtt
    83521 attgctagta actcagtgag aattatgttt gaatctttgg ataaagcaga ccaaattgcg
    83581 gccctgaata tttgtagaaa ctatgtagca cgagaaaatg ttttaaataa agaagatgca
    83641 gaaaaattgt taaatgaaat tgataaaaaa cttgaaatta gcagatagga caattcaaat
    83701 agagttgagt aaaaagtttg aaaagtgaaa caaggagaaa gctatgccag taaatgaata
    83761 tggtcagatg attggtgagt caatggaagg ttatacaccc ggtgcactgc cttctattga
    83821 tttcttagaa gggcgttatg ctaggataga ggctctctcg gtagaaaaac atgcggagga
    83881 tttgctagct gtttatggcc cggatactcc tcgggagatg tggacctatc tttttcagga
    83941 gccagtagca gatatggggg agctggttag ccttttaaat cagatgttgg ctcgtaagga
    84001 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggaa ctttttctct
    84061 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
    84121 gctaaggggt acacggatag gaactgaggc tcagtatctc ctagctcgct atatttttga
    84181 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
    84241 agttgcggag cgtttgggat ttgtctatga aggaaccttc cgccaggcgg tggtttataa
    84301 ggggcgtacg agagatacgg attggttgtc tatgattgat atggactggc ctcaagtcaa
    84361 agatcgtttg gaaacatggc tgcgtcctga aaattttgat aaaaatggac agcagtacaa
    84421 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
    84481 aagctagagg atgttttgca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
    84541 ccagagatgc tggagcatgc cttatcgcat tcattagtaa tttatctggc acttgatggt
    84601 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt ttttgtacag
    84661 gatttgattg ttttaccaat ctatcagcgt caagggattg gtagtgccct aatgaaagag
    84721 gccttaaaag attacaaaga tgcttatcaa gtccagctag tgacagaaga gacagaaaaa
    84781 aacgtgggat tttatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
    84841 atgacttggg cgaatcgaga aaaataacaa aacttgtttt ttcttaagca aaatttaagg
    84901 atggtctagt attatataat cattaaataa agacctccta actttattta ataaaatcct
    84961 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
    85021 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaaggtag
    85081 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
    85141 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
    85201 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
    85261 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
    85321 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
    85381 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
    85441 gagaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
    85501 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
    85561 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
    85621 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
    85681 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
    85741 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
    85801 ggtgtagcag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
    85861 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
    85921 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
    85981 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
    86041 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
    86101 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
    86161 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
    86221 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
    86281 gtgctatgga ggacttctac atcgatatta tgattggggc tggtgagggt agtcgtagtg
    86341 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
    86401 ccaatccgct acgggcacgt tttgggatta caggtcatat ggagtattat gctcatgctg
    86461 atttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc acccatgagg
    86521 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
    86581 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt tatcgatgat gttattaccg
    86641 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
    86701 tccttcgcac catgattgag atgtacggtg gtggccctgt cggattagga actctttctg
    86761 tgaatattgc cgaggagcgt gagactgtag aagacatgta tgagccttac ttgattcaaa
    86821 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
    86881 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
    86941 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
    87001 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
    87061 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
    87121 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
    87181 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
    87241 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
    87301 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
    87361 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
    87421 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
    87481 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
    87541 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
    87601 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataatgaa
    87661 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
    87721 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
    87781 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
    87841 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
    87901 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
    87961 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
    88021 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
    88081 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
    88141 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
    88201 caggtgacat cacagaggaa ttgattggca actatctctt tacccagcat ttgcctaagt
    88261 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
    88321 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
    88381 acgaagtggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
    88441 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
    88501 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
    88561 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
    88621 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
    88681 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
    88741 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
    88801 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
    88861 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
    88921 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
    88981 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
    89041 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
    89101 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
    89161 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
    89221 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
    89281 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
    89341 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
    89401 gggacctaaa atttttgctc acattggcaa ggatggaacg gcctatacca ttcgaatctt
    89461 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
    89521 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
    89581 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
    89641 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
    89701 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
    89761 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
    89821 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
    89881 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
    89941 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
    90001 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
    90061 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
    90121 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
    90181 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
    90241 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
    90301 tggaattgag aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
    90361 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
    90421 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
    90481 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
    90541 atcgaggaat attatgaaac aaagtaaaat gcctatccca acgcttcgcg aaatgccaag
    90601 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
    90661 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
    90721 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctccag cccttcttag
    90781 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    90841 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    90901 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    90961 gcccaagtat cgtgatgaaa aacgcccgcg taatggactt cttcgtacac gtgagtttat
    91021 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    91081 gtacaaagca gcttatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    91141 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    91201 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    91261 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    91321 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    91381 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    91441 agatgttaaa tcaattgatg aagttgcagc cttcctcaat gttccagaag aacaaacgat
    91501 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    91561 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    91621 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    91681 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    91741 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttactgc
    91801 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    91861 ccttaacttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    91921 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    91981 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    92041 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    92101 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    92161 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    92221 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    92281 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    92341 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    92401 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt ttta
//
LOCUS       DBEJNA010000003        90582 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEJNA010000003 DBEJNA010000000
VERSION     DBEJNA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 90582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.03"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..109
                     /locus_tag="ACL3JB_000199"
     CDS             <1..109
                     /locus_tag="ACL3JB_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0685013.1"
                     /translation="EDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
     gene            complement(226..573)
                     /locus_tag="ACL3JB_000200"
     CDS             complement(226..573)
                     /locus_tag="ACL3JB_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0685014.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAALVLDFYRMK"
     gene            complement(684..2459)
                     /gene="spxB"
                     /locus_tag="ACL3JB_000201"
     CDS             complement(684..2459)
                     /gene="spxB"
                     /locus_tag="ACL3JB_000201"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0685015.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2666..4909)
                     /locus_tag="ACL3JB_000202"
     CDS             complement(2666..4909)
                     /locus_tag="ACL3JB_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0685016.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFFCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4919..5290)
                     /locus_tag="ACL3JB_000203"
     CDS             complement(4919..5290)
                     /locus_tag="ACL3JB_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0685017.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKNPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5301..5696)
                     /locus_tag="ACL3JB_000204"
     CDS             complement(5301..5696)
                     /locus_tag="ACL3JB_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0685018.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5880..5978
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6062..6853
                     /gene="thiD"
                     /locus_tag="ACL3JB_000205"
     CDS             6062..6853
                     /gene="thiD"
                     /locus_tag="ACL3JB_000205"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0685019.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGVAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7063..7695)
                     /gene="thiE"
                     /locus_tag="ACL3JB_000206"
     CDS             complement(7063..7695)
                     /gene="thiE"
                     /locus_tag="ACL3JB_000206"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0685020.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7688..8491)
                     /locus_tag="ACL3JB_000207"
     CDS             complement(7688..8491)
                     /locus_tag="ACL3JB_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0685021.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8491..9015)
                     /gene="thiW"
                     /locus_tag="ACL3JB_000208"
     CDS             complement(8491..9015)
                     /gene="thiW"
                     /locus_tag="ACL3JB_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0685022.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9020..9712)
                     /gene="tenA"
                     /locus_tag="ACL3JB_000209"
     CDS             complement(9020..9712)
                     /gene="tenA"
                     /locus_tag="ACL3JB_000209"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0685023.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9723..10373)
                     /locus_tag="ACL3JB_000210"
     CDS             complement(9723..10373)
                     /locus_tag="ACL3JB_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0685024.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10375..11760)
                     /locus_tag="ACL3JB_000211"
     CDS             complement(10375..11760)
                     /locus_tag="ACL3JB_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685025.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11761..12321)
                     /locus_tag="ACL3JB_000212"
     CDS             complement(11761..12321)
                     /locus_tag="ACL3JB_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0685026.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12583..12671)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12880..13509)
                     /gene="thiE"
                     /locus_tag="ACL3JB_000213"
     CDS             complement(12880..13509)
                     /gene="thiE"
                     /locus_tag="ACL3JB_000213"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0685027.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALRGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13511..14293)
                     /gene="thiM"
                     /locus_tag="ACL3JB_000214"
     CDS             complement(13511..14293)
                     /gene="thiM"
                     /locus_tag="ACL3JB_000214"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0685028.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            14395..14577
                     /locus_tag="ACL3JB_000215"
     CDS             14395..14577
                     /locus_tag="ACL3JB_000215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685029.1"
                     /translation="MKIKEQTRKLTADCSKHCFEVVDRTDEVSNHTYGKVKLTWFEEI
                     FEESYLIKFVNIMSLL"
     gene            complement(14574..15242)
                     /locus_tag="ACL3JB_000216"
     CDS             complement(14574..15242)
                     /locus_tag="ACL3JB_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0685030.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15457..15545)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15799..16935)
                     /gene="lctO"
                     /locus_tag="ACL3JB_000217"
     CDS             complement(15799..16935)
                     /gene="lctO"
                     /locus_tag="ACL3JB_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0685031.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKDEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17559..19049)
                     /gene="lysS"
                     /locus_tag="ACL3JB_000218"
     CDS             complement(17559..19049)
                     /gene="lysS"
                     /locus_tag="ACL3JB_000218"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0685032.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19189..19323)
                     /locus_tag="ACL3JB_000219"
                     /pseudo
     CDS             complement(19189..19323)
                     /locus_tag="ACL3JB_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            19539..20219
                     /locus_tag="ACL3JB_000220"
     CDS             19539..20219
                     /locus_tag="ACL3JB_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0685033.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLETISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            20179..20856
                     /locus_tag="ACL3JB_000221"
                     /pseudo
     CDS             20179..20856
                     /locus_tag="ACL3JB_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
     gene            20857..21614
                     /locus_tag="ACL3JB_000222"
                     /pseudo
     CDS             20857..21614
                     /locus_tag="ACL3JB_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21626..21868
                     /locus_tag="ACL3JB_000223"
     CDS             21626..21868
                     /locus_tag="ACL3JB_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGR0685034.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYATILN"
     gene            21910..22491
                     /locus_tag="ACL3JB_000224"
     CDS             21910..22491
                     /locus_tag="ACL3JB_000224"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0685035.1"
                     /translation="MSVDAANRAEYLISNKVDITLANFTVTDERKKQVDFALPYMKVS
                     LGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLD
                     GRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQKDNQELLDFINKDIEKL
                     GKENFFHKAYEKTLHPTYGDAAKADDLVVEGGH"
     gene            complement(22571..23218)
                     /locus_tag="ACL3JB_000225"
     CDS             complement(22571..23218)
                     /locus_tag="ACL3JB_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685036.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23215..23913)
                     /locus_tag="ACL3JB_000226"
     CDS             complement(23215..23913)
                     /locus_tag="ACL3JB_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685037.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23923..24674)
                     /locus_tag="ACL3JB_000227"
                     /pseudo
     CDS             complement(23923..24674)
                     /locus_tag="ACL3JB_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24674..25438)
                     /locus_tag="ACL3JB_000228"
     CDS             complement(24674..25438)
                     /locus_tag="ACL3JB_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685038.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGTVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25534..25656)
                     /locus_tag="ACL3JB_000229"
     CDS             complement(25534..25656)
                     /locus_tag="ACL3JB_000229"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685039.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWNPDSY"
     gene            complement(26117..26749)
                     /gene="pyrE"
                     /locus_tag="ACL3JB_000230"
     CDS             complement(26117..26749)
                     /gene="pyrE"
                     /locus_tag="ACL3JB_000230"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0685040.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFTDAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26783..27484)
                     /gene="pyrF"
                     /locus_tag="ACL3JB_000231"
     CDS             complement(26783..27484)
                     /gene="pyrF"
                     /locus_tag="ACL3JB_000231"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0685041.1"
                     /translation="MREHRSIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27717..28916)
                     /gene="divIB"
                     /locus_tag="ACL3JB_000232"
     CDS             complement(27717..28916)
                     /gene="divIB"
                     /locus_tag="ACL3JB_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0685042.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEIEESES
                     KEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(28926..29984)
                     /locus_tag="ACL3JB_000233"
     CDS             complement(28926..29984)
                     /locus_tag="ACL3JB_000233"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0685043.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(29988..31340)
                     /gene="murD"
                     /locus_tag="ACL3JB_000234"
     CDS             complement(29988..31340)
                     /gene="murD"
                     /locus_tag="ACL3JB_000234"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0685044.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31444..32085)
                     /locus_tag="ACL3JB_000235"
     CDS             complement(31444..32085)
                     /locus_tag="ACL3JB_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685045.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32087..33505)
                     /locus_tag="ACL3JB_000236"
                     /pseudo
     CDS             complement(32087..33505)
                     /locus_tag="ACL3JB_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            33672..35018
                     /locus_tag="ACL3JB_000237"
     CDS             33672..35018
                     /locus_tag="ACL3JB_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR0685046.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADVYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDENLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFFKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            complement(35208..35816)
                     /locus_tag="ACL3JB_000238"
                     /pseudo
     CDS             complement(35208..35816)
                     /locus_tag="ACL3JB_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(35887..36186)
                     /locus_tag="ACL3JB_000239"
                     /pseudo
     CDS             complement(35887..36186)
                     /locus_tag="ACL3JB_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(36550..36804)
                     /locus_tag="ACL3JB_000240"
     CDS             complement(36550..36804)
                     /locus_tag="ACL3JB_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0685047.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(36824..38665)
                     /gene="typA"
                     /locus_tag="ACL3JB_000241"
     CDS             complement(36824..38665)
                     /gene="typA"
                     /locus_tag="ACL3JB_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0685048.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            38827..39552
                     /locus_tag="ACL3JB_000242"
     CDS             38827..39552
                     /locus_tag="ACL3JB_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0685049.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(39592..39819)
                     /locus_tag="ACL3JB_000243"
     CDS             complement(39592..39819)
                     /locus_tag="ACL3JB_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685050.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(39908..40288)
                     /locus_tag="ACL3JB_000244"
     CDS             complement(39908..40288)
                     /locus_tag="ACL3JB_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0685051.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(40288..40557)
                     /locus_tag="ACL3JB_000245"
     CDS             complement(40288..40557)
                     /locus_tag="ACL3JB_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0685052.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            40621..41529
                     /locus_tag="ACL3JB_000246"
     CDS             40621..41529
                     /locus_tag="ACL3JB_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0685053.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(41583..42338)
                     /locus_tag="ACL3JB_000247"
     CDS             complement(41583..42338)
                     /locus_tag="ACL3JB_000247"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0685054.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(42359..43288)
                     /gene="rnz"
                     /locus_tag="ACL3JB_000248"
     CDS             complement(42359..43288)
                     /gene="rnz"
                     /locus_tag="ACL3JB_000248"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0685055.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(43303..43926)
                     /locus_tag="ACL3JB_000249"
     CDS             complement(43303..43926)
                     /locus_tag="ACL3JB_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0685056.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(43919..45157)
                     /gene="hflX"
                     /locus_tag="ACL3JB_000250"
     CDS             complement(43919..45157)
                     /gene="hflX"
                     /locus_tag="ACL3JB_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0685057.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(45150..46034)
                     /gene="miaA"
                     /locus_tag="ACL3JB_000251"
     CDS             complement(45150..46034)
                     /gene="miaA"
                     /locus_tag="ACL3JB_000251"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0685058.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRREQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            46155..46325
                     /locus_tag="ACL3JB_000252"
     CDS             46155..46325
                     /locus_tag="ACL3JB_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0685059.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(46373..47212)
                     /locus_tag="ACL3JB_000253"
     CDS             complement(46373..47212)
                     /locus_tag="ACL3JB_000253"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0685060.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLKTNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(47309..48268)
                     /locus_tag="ACL3JB_000254"
     CDS             complement(47309..48268)
                     /locus_tag="ACL3JB_000254"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0685061.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KSLGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(48395..49273)
                     /locus_tag="ACL3JB_000255"
     CDS             complement(48395..49273)
                     /locus_tag="ACL3JB_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR0685062.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGTFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGAYYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGA
                     YYLKSNGKMAQGEWVYDATYQAWYYLKSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGG
                     RYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFD
                     KFSNDAAQYAIDHLDD"
     gene            complement(49323..49940)
                     /locus_tag="ACL3JB_000256"
     CDS             complement(49323..49940)
                     /locus_tag="ACL3JB_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0685063.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQYLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIISDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(49941..51662)
                     /gene="pabB"
                     /locus_tag="ACL3JB_000257"
     CDS             complement(49941..51662)
                     /gene="pabB"
                     /locus_tag="ACL3JB_000257"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0685064.1"
                     /translation="MHRKTVIDFRTLGERYTFIQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAENYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     KIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     KHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(51723..57275)
                     /locus_tag="ACL3JB_000258"
     CDS             complement(51723..57275)
                     /locus_tag="ACL3JB_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0685065.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSVESAPVEEVGGAVDSKTDEQAPVKSESQPSDKPAEES
                     KVEPSVEPVAPREDEKAPTAPVEPEKQPEVPEETVEPKEETKTAKGTQEKGKEGQAPV
                     QEVHPEYKVTTGTVEKSIESELDFTTDVVPDDTKYVGDEVVENPGSKGVQVTKTTYET
                     VEGVETDKVLSTSTEVTKEPVNQQVIRGTKPIEGTLIEESLEKIPFKEVVKEDDQLKK
                     GLEVVAQEGKEGQKKITKTFNTIKGVKTEDAPKVTEEILEEPQDKILKRGTKSFEKPV
                     LTITEIESKDLKRTSDVKYSLENPSKAAIKSITLTLKKGDEIVKTLNVSPEDLTTTLT
                     DLQYYKDYKLETKMVYDRGEGDEEEVLKEEPLRIDLKKVEIKDIIRTDLIKYENQVET
                     DETRLTSVPTDLSNYYLKVTSNDHKTNLLAVQKIEESTIDGKQVYKVIAVADNLVQRN
                     VDNRFEETYTYYIEKPKASQAGIFYDFEELIQAIQTNPAGEFKLGQSMSARNVVPKGK
                     SYITSEFTGKLLSDGDKRYAIHNLEHPLFDKIKAGTVKNINFENIDIDLSNQDNIAAI
                     ANEISGTTRIENIKAIGTITARNNVAGFVNNIKEDATLENVAFIGSINSAGNNSTVGG
                     IAGSNYMGFVNRAYVDATITANNANASMLVPFVQYKAHSWLSGTKGKLTNSVAKGILD
                     VKNTKYVGGITSKTWPYGAVQDNVTYAKVIKGQEIFGSNDVNDGDANPFVSNLFGVIG
                     YSSSEDGTGKDNKNKNKLKHLSKSEADAKVASFNITAAKFVSEPYELNKLNNVSSREA
                     AYESIQDYNADYKLAYKNIEKLQPFYNKDFIVNQANKLDKNNKLNTKEILSVTPMNNN
                     NFVTDLGDANKIIVHYADGTKDYFNLSSSDEGLSNVREYTITDLGIKYTPNIVQKDHS
                     ALINGIVNILSPIELQSNPIYQKLGRTGSNRVNAIKDLYLEESFDHVKANLNILVTKL
                     VENEDHQLNNSSAAQQMILDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPD
                     FYGKNVSVLDRLIEIGSREDNIKGHRTYDAFSEIISKTTLSENLVNFLNYNRRLFTAD
                     VNIYDWFKKATEGNVYIAERASEVDEIKAAKYKVWDNLQSATHRKMILPLLNLNKSHV
                     YLISNYSAMAVGTAEKLGHSSFDGIKNQIEKAADSYRNYFDFWYRLSLDKVKNMLVKN
                     TVTPLWEGYQAPGGWPDKYGKRNNKEDYAPLRELFGPIGKYYGNNGTGAYAVIWDNPL
                     DTRTEVNYIALSMIDEFGISVYTHETTHVNDRAIYLGGYGRRSGTHAEAYAQGMLQTP
                     VPSTWFDEYGALGINMTFYRPNDGNQWYITDPKTLKTREDIDNYMKGYIDTLSLLDYV
                     EGDAVISKHDDKLNQLWFKKVDPIERTVGSKDQYDKVRNMSSDDWKGITLNSVNDLVD
                     NNLMTNRMMNNNIYKPEVFDPGIAYVGIKMMNSIYAGNTSEGAPGAVTFKNNAFRLWG
                     YYGYDKGFLGYASDKLKSQANKEGKQFGDQYIIQKISDGRFQSFADFKKEYYKELLEK
                     ANAGFTPFTIDGETIHNYDELKSLFAKALEEDMVTNKVNGKLVQVKEKVYKKLLQQTN
                     SFKTSIFK"
     gene            complement(57297..57860)
                     /locus_tag="ACL3JB_000259"
     CDS             complement(57297..57860)
                     /locus_tag="ACL3JB_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0685066.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(57976..59667)
                     /locus_tag="ACL3JB_000260"
     CDS             complement(57976..59667)
                     /locus_tag="ACL3JB_000260"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0685067.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFEANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(59664..60401)
                     /locus_tag="ACL3JB_000261"
     CDS             complement(59664..60401)
                     /locus_tag="ACL3JB_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0685068.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(60624..61736)
                     /gene="msrB"
                     /locus_tag="ACL3JB_000262"
     CDS             complement(60624..61736)
                     /gene="msrB"
                     /locus_tag="ACL3JB_000262"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0685069.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(61747..62313)
                     /locus_tag="ACL3JB_000263"
     CDS             complement(61747..62313)
                     /locus_tag="ACL3JB_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0685070.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(62333..63043)
                     /gene="ccdA2"
                     /locus_tag="ACL3JB_000264"
     CDS             complement(62333..63043)
                     /gene="ccdA2"
                     /locus_tag="ACL3JB_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0685071.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(63254..64114)
                     /locus_tag="ACL3JB_000265"
     CDS             complement(63254..64114)
                     /locus_tag="ACL3JB_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0685072.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(64293..66347)
                     /locus_tag="ACL3JB_000266"
     CDS             complement(64293..66347)
                     /locus_tag="ACL3JB_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0685073.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(66359..66613)
                     /locus_tag="ACL3JB_000267"
     CDS             complement(66359..66613)
                     /locus_tag="ACL3JB_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685074.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(66606..67163)
                     /locus_tag="ACL3JB_000268"
     CDS             complement(66606..67163)
                     /locus_tag="ACL3JB_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0685075.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(67147..68103)
                     /locus_tag="ACL3JB_000269"
                     /pseudo
     CDS             complement(67147..68103)
                     /locus_tag="ACL3JB_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            68195..68554
                     /locus_tag="ACL3JB_000270"
     CDS             68195..68554
                     /locus_tag="ACL3JB_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0685076.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            68932..69009
                     /locus_tag="ACL3JB_000271"
     CDS             68932..69009
                     /locus_tag="ACL3JB_000271"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685077.1"
                     /translation="MLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            69390..69620
                     /locus_tag="ACL3JB_000272"
     CDS             69390..69620
                     /locus_tag="ACL3JB_000272"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0685078.1"
                     /translation="MNERYQNLKAKECQALLSPQDRQIFAQRKIDVEPVFGQIKACLG
                     YKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(69868..76569)
                     /gene="bgaA"
                     /locus_tag="ACL3JB_000273"
     CDS             complement(69868..76569)
                     /gene="bgaA"
                     /locus_tag="ACL3JB_000273"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0685079.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQIFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAKLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDSYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(76657..76803)
                     /locus_tag="ACL3JB_000274"
     CDS             complement(76657..76803)
                     /locus_tag="ACL3JB_000274"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685080.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSNHIYGKATLTKFELD
                     FRRV"
     gene            complement(76829..78304)
                     /locus_tag="ACL3JB_000275"
     CDS             complement(76829..78304)
                     /locus_tag="ACL3JB_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0685081.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(78352..78657)
                     /locus_tag="ACL3JB_000276"
     CDS             complement(78352..78657)
                     /locus_tag="ACL3JB_000276"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0685082.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            complement(78695..79171)
                     /locus_tag="ACL3JB_000277"
     CDS             complement(78695..79171)
                     /locus_tag="ACL3JB_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0685083.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYAYIAEATA"
     gene            complement(79798..86217)
                     /locus_tag="ACL3JB_000278"
     CDS             complement(79798..86217)
                     /locus_tag="ACL3JB_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0685084.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            complement(86749..86946)
                     /locus_tag="ACL3JB_000279"
     CDS             complement(86749..86946)
                     /locus_tag="ACL3JB_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685085.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFLQLWNPQNPCQILIKKLE"
     gene            complement(86931..87209)
                     /locus_tag="ACL3JB_000280"
     CDS             complement(86931..87209)
                     /locus_tag="ACL3JB_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0685086.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(87248..88033)
                     /locus_tag="ACL3JB_000281"
     CDS             complement(87248..88033)
                     /locus_tag="ACL3JB_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685087.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(88035..88853)
                     /locus_tag="ACL3JB_000282"
     CDS             complement(88035..88853)
                     /locus_tag="ACL3JB_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685088.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(88855..89847)
                     /locus_tag="ACL3JB_000283"
     CDS             complement(88855..89847)
                     /locus_tag="ACL3JB_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685089.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(90248..90493)
                     /locus_tag="ACL3JB_000284"
     CDS             complement(90248..90493)
                     /locus_tag="ACL3JB_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685090.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
BASE COUNT        26726 a        19666 c        16201 g        27989 t
ORIGIN      
        1 ggaagatgtc atgaatcaac ttcaagatgt catacaagga ctggagaagg aggtgataaa
       61 gtccatcgtt aatcggagat ggactagaat gctttttgaa agcagatgag tattatatgc
      121 aatttcttta tataaaaaga ccggattgct ccgatctttc aatagttcat attctcaatt
      181 tctattttaa aaatagctaa ggttaacgtc aaatgactac gcgacctatt tcatacgata
      241 aaaatcaagc actagagcag caggtccttg aactaataag gactctgttc cccaatcggt
      301 tacagttggt ccgtgtaaaa cctttatacc aagctcgttc aaccgtttgt agttctggtc
      361 tacatcctca acctcgatat gaataatgat tcctgactga aagttttcca aaggaaccaa
      421 atgattttgt gacaacataa ggcagtgact accaatcgta aactgagcaa aaccatcatc
      481 agcataatct gcctttttat ccaagatatg ctccaagtca gcacagactt ggggaacatt
      541 tgaaacgata atatctaatt gatttaaatt catttactct cctccataaa aagaccggat
      601 tgctccgatc ttttaaagtt ctgctctatg aaaatcaaag aataaagtct acaagtttca
      661 tatttgattt tcggcgagag gaattattta attgcgcgtg attgcaatcc ttcttcttcc
      721 aagaagagac ggaatggtac gagttcttct gcttcgtatt tttccttgaa ggctttgata
      781 gcttcttctg agtgaagttt tggatccaat tcaagtactt ctactggaag tggacggtgt
      841 tgagtgatgc gagcatcgat gacaacagtt ttaccttctt tgttcaattt aacagcttct
      901 gcaacaactg catcgatgtc ttcgatacgg tcaactgtga atccaacagc tccttgagct
      961 tccgcaattt tagcgtagtc agcgtttgtg aagtctacac caaacaagtg tttgtttgta
     1021 tcttcgtatt tgttcttgat gaagccgtac tcagcatttg agaagacaag gttgataact
     1081 ggaaggtcgt attgaacgtt tgtgataacg tctgggtagc acatgttgaa tgctccgtca
     1141 cccatgatgt tccatacttg gcgatctgga ttgtctttct tagcagcgat accaccagga
     1201 agggcaatac ccattgtcgc aaagagtgga gatgtacgcc acatgttctt aggtgtcatg
     1261 tgaaggtgac gagtagatgt ttgagtagtg ttacctacgt cgattgagta gatagcgtct
     1321 tgatcagcat gtttgttgat tgcattgtaa acttgataca attgcaattc accctcagtt
     1381 ttaccttcga gtttgttcat gtaatcacgc cagttttggt tgttcttaac gtttgcacgc
     1441 caccatggag ttgattcaac tgggtttact ttgtcaagga tagctttagc tgcttgacca
     1501 gcatcaccaa ggattgaagc gtcaagggca tgacgtttac caagtttgta agggtcgata
     1561 tcgacttgga taaatttttc agtgttcttg aatgcttcgt aaacttcagc aaatgggaag
     1621 tttgaaccaa ggaaaagaac tgtgtctgct tcaaagacca cttcgttggc tggtttccaa
     1681 ccaacacggt aagcagaacc tgtcaaacct tcatagttcc attcgaaagc ttcaaagttt
     1741 ttaccagttg tgatgattgg tgctttgatt ttacgtgaca attcagtaat cacttcacca
     1801 gctttaacac caccaaatcc agcatagata actgggcgtt cagcattgtt caagatttca
     1861 acagctttgt cgatttcaac ttcgttcaaa gcaggagcga tgaatgagcg ttcgtatgaa
     1921 cctgaaccgt agtatgagtt ttcgtcgatt tcttggaaac cgaagtttac tggaatttca
     1981 acaacagctg gacctttttt agaaactgca gcacggcagg cttcgtcaat tacttttggc
     2041 aattgctcag cgtaagctac acgtttgttg taaacagcga taccgttgta cattgggttt
     2101 tggttaagct cttggaaagc atccatgttc aattcgttaa ctggacgtga tccaaggatt
     2161 gctaggaatg gagtgttatc catagctgca tcgtaaacac cgttaatcaa gtgagtcgca
     2221 cctggaccac ctgaaccaac tgcaaccccg attgagccgc cgaatttagc ttgcataacc
     2281 gctgcaagag cacctgtctc ttcgtggcga acttgtaaga agcggatatc tttgtcttca
     2341 gccaaagcgt ccatcaatga gctgagtgtt cctgatggga taccgtagat tgtatctacg
     2401 ccccatgttt tcaatacgtt aagcattgct gcagatgcag taattttccc ttgagtcata
     2461 atgataactc tccttcaatt tttttagact tggagaatac gattacatag aattggaaac
     2521 gttctccaaa tttttactat tccactgtat catatttatg ctgacttttc taaaaatctg
     2581 ctcaaaactc tctattctct attctaatac agttttgaaa gtgtcgtcat ttctgtttta
     2641 taacaaaaaa atctagtcat tacttttagt ctattttact aaaatttaac agaagggaac
     2701 tggtcagaac agatacagaa ctaaaggcca tggctagacc tgccaattct gggttgagag
     2761 ccagtccaac acctgaaaag actcctgctg caatcggaat tccgacaaca ttgtagataa
     2821 aagcccagaa aagattgagc agaatacgat gaaaggtttt cttactcatg tcgaaggcac
     2881 gcaccactcc taaaagatta ttggttgtca acaccaaatc tgctgactcg atggcgatat
     2941 ctgttccagc tcccatagca atccccacat ctgctacact aagggcagga gcgtcattga
     3001 tcccatcacc aacaaaggct actttacctg actgttgcag tttatggatt tcatgggctt
     3061 tttcttctgg caagacgcct gcaatgacct cttcaattcc gatttgatct gcaatagcac
     3121 gcgccacacc agcattgtct cctgtcagca tgactgtccc gagaccacgt ttttttagct
     3181 gactgatggc tagcttagca tttttcttag gaatatcttg caaagcaagc aagcctttga
     3241 tttcattgtc aacagctaag aacacaactg tcttagcttc tttttctagt tcttctagtt
     3301 tatcttgata agtattagaa atatccatgc catccagcat tttagcattt ccaagtaaaa
     3361 cttgttttcc attgattcgc cctgaaacac ctttcccgtg caaggcctga aaattttcaa
     3421 cagtttgaaa ctcaagtcca gcttcactcg ctcgcttaac gatagcctca gccagtgggt
     3481 gttgagaagc atcttccaag gaggctgcca atccaaacac ttctacttcg tcgccgatga
     3541 catctgttac cacaggtttc ccttccgtca aagtcccggt cttatcaaag acaagggttt
     3601 gaactttctg gatttcctgt aagacagttc catttttgag gagaaccccc atcttggcac
     3661 tacgtcctgt ccccaccata agggctgtcg gtgttgcaag tcccaaggca caaggacagg
     3721 cgataatcaa aaccgccact ccgtagagaa gagaggacac aaagctagct ccaagcacaa
     3781 ccacactatc cctgagcaag acgaaccaaa cccaaaaggt catgattcct aaaatgacaa
     3841 ctactgggac aaaaatccct gaaatcttat ccgtcaagtc ctgaatcggc gcacgacttg
     3901 tctgagcttt cttcacaaaa tccacaatct gagccaaaac agtctctgag ccaacttttt
     3961 ctgctctaaa gacaagcgtt ccactatgat tgatggttga gccaatgaca gtatctccaa
     4021 ctgtcttgtc cacaggcaga ctctcacctg tcaccatgga ttcgtcaata ctagagacac
     4081 cttctactac gacaccatca acagcaatct tttcaccggg acgcactcga atcaggtcgc
     4141 ctaccttgac ttgttccaaa ggaacttgga cataactatc atcactcaag acttctgcgg
     4201 ttttagcttg caagtccagt aatttctcca cagcttggga cgtatttttt ctcatttttt
     4261 cctcaaaaac tgctcccaaa agaacgaaaa agaggataaa tccagcactt tcgaagtaaa
     4321 cagggagacc agcaaagaga gcaactaggc tatagaaata agccactaga gttcccagcg
     4381 caaccaaggt atccatgttg gcattgtgct ttttaaaact ggcccaagca ctctggatat
     4441 atggcttacc tgcaactaac ataataggcg ttgttgctag aaaggttccc caatgcatga
     4501 cttgatgact aatgctacct gtcaacatcc caatcatgag aatcacaaga ggcacagtaa
     4561 agatactagt aatccaaaaa cgttgcagga gagatagaga ttttcgagtc ttctcaacga
     4621 ctgtatagct tcccttttgc atcttcatgc cacaaaaaaa ttcatgtcgc cctaattctt
     4681 gaggtgtaaa acgaatgact ttctcctcat ctacgccgat tggttccaag ataccttctt
     4741 cttcaaacag aatttcctta taacagtttg aaggagtagc acgatgaaag gtaatctcag
     4801 ctggaattcc cttttgaagc tggatatggg ctggatgata gcctttttca gatcggatac
     4861 ggattttttg aatgccattt tctaagcttg ctttcacaat ttctgtcata gtctccacct
     4921 actctacaat catcttgccg tgcatcatgt tcataccaca agcaaagcca aattctccag
     4981 cctgttcagg cgtgatttcc actacatact cttcccccat tggcaggttc gtatgtacac
     5041 caaaatctgg aaaaacaatt tgatccagac atggtgaagg atccttgcgg tcaaagacaa
     5101 tgcgggctgg cactgatttc ttgaggacaa tcaactcagg agtatagcct cccatgactt
     5161 ccactcgaat ctcttggtat ccgttttttt gctgggcttt ttgtccagat ttttcaggat
     5221 ttttgaaaaa ccaaaacaag ataaacgcga taagggcaat acaaataatg gttacaatac
     5281 tatttaacat gacgtctcct ttacatacaa ttacatctta cttctgttac agcacttgat
     5341 ttcttctctg aaatcacagc ttccaagtct tccaagtcag tctgagtaaa ttcacattct
     5401 acaatcaagt cagccaacaa attcctaatc ctacgggaac aaaccttgtc tttgatatct
     5461 tggacaagta aatcccgact ttggtctaga gttaaaagcg ctgaataaac aaaggacttg
     5521 ccttcttttt tccgagtcaa acactctttc tcaactagac gagccaaaag tgtctgaacc
     5581 gtggacttgg accagtcaaa ccgctctgcc aaaaccctaa tcaaatctgt actggtctgc
     5641 tccccctgca tccaaataat cttcatgacc tgccattctg catctgaaat ctgcattacc
     5701 atacctccaa aatctacatt tgtcaattac actcaacagt atactcccaa aatctacatt
     5761 tgtcaattat agaaataata ttttcttcga aaaatagaat tttaatcatt tgaaaaacga
     5821 tttgcagtca aatattacta tataaacaat aaaaatatgc tatactaaag aaaaaagaaa
     5881 acaaccacta ggggtgcgta aagctgagat taacgactgt tagatccctc tgactcaatc
     5941 taggtaatgc tagctgatgg aagtggaaat gataatgggg actagcagtc ttctattgcc
     6001 tttctaaaac agactagctt gttcttaaga atacaaactt cagttggttg ggaggtttta
     6061 gatgacttat ttacccgttg ctttgaccat tgcagggact gaccctagtg gtggtgctgg
     6121 cattatggca gatttaaagt cattccaagc gagagatgtc tatggagtgg ctgttgtaac
     6181 cagtcttgtc gctcaaaata ccagaggtgt tcagctaatc gagcacgttt ctcctcaaat
     6241 gttgaaagcc caattggaga gtgtcttttc tgatattcca cctcaggctg taaaaactgg
     6301 aatgttggct actactgaaa tcatggaaat catccaaccc tatcttaaaa aactggattg
     6361 tccctatgtc cttgatcctg ttatggttgc tacaagtgga gatgccttga ttgactcaag
     6421 tgctagagac tatctcaaaa caaacttact acctctagca actattatta cgccaaatct
     6481 tcctgaagca gaagagattg ttggtttttc aatccatgac cccgaagaca tgcagcgtgc
     6541 tggtcgcctg attttaaaag aatttggtcc tcagtctgtg gttatcaaag gcggacatct
     6601 caaaggtggt gctaaagatt tcctctttac caagaatgaa caatttgtct gggaaagccc
     6661 acgaattcaa acctgtcaca cccatggtac tggatgtacc tttgctgcag tgattactgc
     6721 tgaactagcc aagggcaaga gtctttacca ggcagttgat aaggccaagg cctttatcac
     6781 aaaagctatt caagatgccc ctcaactcgg tcatggttct ggtccagtca accatacaac
     6841 ttttaaagat taagaaaaaa aactctctag ttcccacttt aagggaatta gagagttttt
     6901 atactcttcg aaaatctctt caaactacgt cagcttccat ctgcaacttc aaaacactgt
     6961 tttgagctga cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg
     7021 actagctttc tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg
     7081 caactttgtt aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg
     7141 tacaacagct acaccagcta tgccagtgcc cataagctga tcaatattct ccgaagtcaa
     7201 gccaccaata gcaactattg gaatggcaac cgtttggcaa attgttttca aggttgaaat
     7261 cagggtgatg ggtgcatttt ccttggtggt tgtcggaaaa atggctcctg tccccaagta
     7321 atctgcacct gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag
     7381 gattttttca ggacccaaga cttgtcgggc aaccgaaact gggagttcgt catctccaat
     7441 atgcagacca gcagcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg
     7501 tacctgataa gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt
     7561 tgtgagattt ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac
     7621 ttttgcaaga aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag
     7681 tgcttctcta ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta
     7741 ggagcgaaag ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa
     7801 ctattttctc agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag
     7861 tctttccttg gctgagaaaa acggctgtta aggctccaac caaatctcct gtccctgtta
     7921 tccagtctaa ttctgcacag ccatttccca gtacagcgac ctgatttttc gaaacgacga
     7981 ggtccttggg acctgtgact aagaaagaca taccatgata ggtctgacac cagtctttca
     8041 agacttgaag caaatcctcc gtttcttgat ctttagcact cgcatcgacc ccaacgccgt
     8101 ggtgctttaa tccaacaaga cttcgaattt ctgacatgtt tcctttaagg accgtaggtc
     8161 tatagtctaa aaggtctctg actaagctct tacgaatgga tgaagctgtt acgccaaccg
     8221 catctactac cattgggaga caaacttgag ctgcataaga agctgctata cggattgctt
     8281 tctccttctc agctgacaaa tgccccaaat tgatgaagag agcctgactt tgcttagtaa
     8341 aatcaagaac ctcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc
     8401 catttgccag catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc
     8461 ctataggaaa gggatttgta aattcctgca tcagtctatc ctttcactaa agaaatatcc
     8521 ctgcactttt ttaaagaatt cctgcttgat taaaaatcga aaggcaataa aggaaatcgc
     8581 tgtaccaatc aaggttgctc cgaaaaatcg aggcgtgtag ataaaccagc taagcttagc
     8641 agctgatcct gtaaagagta ccataacagg ataggaaaca atagaaccaa taatacctgt
     8701 tcccacaatt tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc
     8761 tgctagaagg gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt
     8821 catacggata aaggctgtca ctgtagccat ggccaaggca taaacaggtc ccatcatgat
     8881 tcccgctaga atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg
     8941 tgtaaggact acatcaaggg cagtcatcat agataaaatg gtcaatttgt gaacttgtag
     9001 ttggtgcttt ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc
     9061 atgtctggtg ttggtaagcc atctcccaaa acttggcttc catatgaaca ctgatgtgga
     9121 aggcatctag cattttttgc ttatctgtct catcactttc tcgatagagc tgattgacca
     9181 gtgctccctc ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt
     9241 gttgatagag aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata
     9301 accaaggaca aggaagcaag cttgcaaaag ctatggctaa gttcggttct gcaaattgcc
     9361 tataaatatg agaaatgtaa tgataacagg ttggagcgat tggatgttgc tccatttcct
     9421 ggtcgttgat ttccaattcc ttgaaaaatt gttggcgaat aaataactca ccctccacta
     9481 aaccctgagc attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca
     9541 aaagatgata gatttctgag aaagccttca gatagtaggc atcctgaatc aggtaatagc
     9601 ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg
     9661 aagcctgcca agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc
     9721 ctttataaaa atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt
     9781 tttttaggaa tataaaaagt ccgatagcta ttcttcaact gtgcatgttc gtcatatccg
     9841 tgagcagata gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta
     9901 ctgtaaatca agggcgacca aaaatgtagt ttttgaccac gtaataggca agcttctttg
     9961 agggacttga tttcttgctg aatgagagga aaagaattga ataccacaat caaggcatag
    10021 gaccaagagc gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata
    10081 gaggaaacaa agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact
    10141 gcctgtgaag catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg
    10201 gcaagtatga tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata
    10261 caaaatgcga ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat
    10321 aaaatcagca agaagagact gataatcggt gtctgggttg ctactttgac catactatct
    10381 cacctcccct tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt
    10441 cacatgccga agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg
    10501 gtctaaacga tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca
    10561 cttgcaaaaa taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat
    10621 cacggaagcc ttactggtca agatggtcag gagctgaaga attttttgct gaccaccact
    10681 taattgatag ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa
    10741 aatccgctga tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac
    10801 tcggataaac tgcttctcag cttcctgaac aacaccagtc agatcacgat acaaactctt
    10861 tttctttttc aggaccgaac ccttccatgc aatgcgcccc ttatactttt gaaattgaag
    10921 aatagaccga aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc
    10981 ttgatagaat gtgaaatcag caattgaaaa gagggggcga tttccaaact cacaagtcgt
    11041 tctatccata tggaatagtt ccgggctaga agcaacttcc tttgaagcaa cctgtgtcat
    11101 ctcataggaa gggatttgaa acacttccct tagttttccg tctcttagct caaccatatg
    11161 gtcgatatag gctttatagt cagataaatc atggtcgcac aaaataactg tctttccatc
    11221 aagagccaac tcttttagaa tctccaatat ctcgattctg ctcttgcggt caatggaagc
    11281 aaaaggttca tccaagagat agaccctagg attcatggca aagaggacag ccagcgctgc
    11341 tttttgcttt tccccacctg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg
    11401 acattgctgg acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt
    11461 ctccaaggtg aaaatcagct cctcaaacaa gctctccatg gtaaattgat gattgggatt
    11521 ttgaaagaga atgccaacct tctggacacg tgcgatgata gaaagttgac tgacctcgct
    11581 cccatctatc aggacttgac cactataggg aagagaactg acttgagcaa tgacttgaaa
    11641 aaggctggat tttcctgaac cactgctccc aactaacaag gtaaaggctt gcgcatgaaa
    11701 agtaaaatca aacggctcag agaagattgg ggactgaatc gctcgtagtt ccagacccat
    11761 ctatgctttt cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat
    11821 ggtacagaag aaataaacag aaataaaacg taccacaagt aaggaaagga caaacggaag
    11881 ggaaaaggcg tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc
    11941 aatactatta gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc
    12001 aaattcactt cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct
    12061 accataaagg acttcagcaa gcgcagctag cacttctcca atcgttgcac ttccgactct
    12121 cggaacaaag atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt
    12181 ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc
    12241 tgaaccaacg aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt
    12301 taactgccat tttttcaaca taaaaaactc ctttttttaa agaaaagtgg ggcactcaag
    12361 aagaccgacc taaatacttt gtatagcaga ctgaatttag aacagtacac aagaatgcta
    12421 aaatatttct agaaattaat ttgaattttc taattgattt gttcgcatct tatttcaatc
    12481 tactatatca tcttcatcca gtttcgtaaa agaaaaaact ctaattacag atacgaatta
    12541 gagttcagct tacaagatta gacagttctt ttcgacatac gaaaaaaaca tttcacattt
    12601 cccttcgcca gtcttaactg tatcaggttc aatgggtatc atctcagcct aaagcacccc
    12661 aaatgccttt attatttaat tatgtgatta ttataacaca cattttatac tagttcaaga
    12721 aattgaactg gaaatacagc cttgcactca caaagacagc agatctttct tttgcaaaaa
    12781 acaaatgacc tgtttgatga attagctatt caagctgaat ctagacatag ttttttaaaa
    12841 aaggaaaatc ctacttactt agaatccaag gatagatatc tattgttcac tcatttcccg
    12901 aacagttttt tctatatttt ttgcatacga tattgccgaa atgattgaaa cgccgtcaac
    12961 attggtcttc ataatgtctt taatatgttt cgtctgtatc ccaccaattg caactaaggg
    13021 catttgtggc aatagttttc tcatcaattt aacaccttca taacctatag caccaccagc
    13081 atcatccttt gactgggtat caaatacagg accaacacca acataatcta catattcaac
    13141 ttttgattgt tgaaattctt cctcgttttt tatagaaaga ccaattattt tatctggcat
    13201 caattttcta atttcatcaa caccaatatc atcttgacct acatgtacgc catcagcgtc
    13261 aatttccatt gccaaatcga tatcatcatt aacgataaac ggcacattgt attttttaca
    13321 aagttcttta atttggatag ctagctcaag tttttctaag ccttctaaag caccctcacc
    13381 tttttctcga aattgaaata aggttatacc acctcttaag gcttcctcaa cgactgtata
    13441 tagatttttt ccttggcaag tagtcgttcc acaaataaaa tatagtttta gtaattcttt
    13501 atgaaacatc ttacttcact cttttgaatt cctttacatc ttcatctgta atctcgtata
    13561 aggcatttat aaattcaact ttaaatgtcc caggaagatg tccatttgga cgtttttctg
    13621 ccatttctcc agcgatattg taaaccaaca ttgctgtttc taatgatttc aattcttgac
    13681 ctttttctag tccgataaag cttgctacca ctgcccctaa taaacatcca gttccaataa
    13741 cttttggcat catggcacta ccattatgaa tcgttaccac ttctccattt accgcaatag
    13801 catccacttc acctgttact actattggaa tattgaactt ctcatttgct gctagagcaa
    13861 tctcgtcaat attatctact cccgcactat ctactccttt agatgccaca tctattccta
    13921 ctaaagaggc aatctctcca gcattccccc taatcgcagc tagtttgtaa ttgttgatta
    13981 aatcatctgc tacttttttt ctatattctc ctgctccaca ggctacagga tctaaaacta
    14041 ctgggacatt atatttctct gcaattttca gagcagcttg gtataatttc caattttcat
    14101 ctgtcaatgt tcctatgttt attaataaac caccagcata ctttaacaaa tcctctaaat
    14161 ctgctggaaa ctcactcatg gctggtgagg cgcccagtgc tactaatcca tttgctgtga
    14221 aattttttac tacatcattg gtgatacaaa tgaccaatgg tgctttttct tttaataatt
    14281 ttaaacttgt catattgaaa tccttccttt tcactttata cgatctactg atttcgattt
    14341 atttctatct ttcgttaaga atttttttca tttacattga atgatttata ctcaatgaaa
    14401 atcaaagagc aaactaggaa gctaaccgca gattgctcaa aacactgttt tgaggttgtg
    14461 gatagaactg acgaagtcag taaccatacc tacggcaagg tgaaactgac gtggtttgaa
    14521 gagattttcg aagagtctta cctcatcaaa tttgtaaata tcatgagcct tctctagaca
    14581 tcgtaaccaa tatcaaaaaa agctaattct aaagcgactg cttgattcca tcgttgctga
    14641 agttctgtca aatcttctcg atttttaccg acacgattga gttcgtcaac cagaaattga
    14701 acccactctg caaagaaagg acctctgtgg agattgatcc attccgaatg aatatagact
    14761 tcaggtagag ccaaatcttt agaaccccag tctaaataga gaccttctgc aatgaccagc
    14821 ataaccaaaa gatgggcata gtctgatgaa gccactgccc aatacattag atcctgaaag
    14881 gcttttgtta cagggtgcaa agtcacttct agatagtcat tctctgctac ttttaactct
    14941 ttaaaagcct tttggaaata accatcttca tctgcttcaa gaaagcctag ttgcttggca
    15001 aaacgaagct tggattcaag tttatctgcg tgagctacgc aggcacccag catggataag
    15061 aaggcatcaa agaagtgata atcttgaatc agatagtcct ttaagacctt attctcaatt
    15121 gtccccgcaa aaagttcctt aacaaaacga tgattgattg cagcctgcca atccttctga
    15181 ctgcttttta ataattctcc aacagtcaaa cctggctgaa atgcatagtc ttgtgtttcc
    15241 atatttactt ctcctctctt tacttgttag taattaataa aacaccaaga aatatcaagc
    15301 aaaatcgtaa ttccacttga tccttttaaa acacatcgag agtatttgca gagagctaac
    15361 taaacaagcc tatccagttt atataaacaa aaaactccaa ttacaatcaa gaattagagt
    15421 tgacttacaa gattagaccg ttcatttcac catacgaaaa aactgttcac atttcccttc
    15481 gccagtctta actgtatcag gttcaatggg tattatctca gcctaaagca ccccaaatgt
    15541 ctctattatt taattactga accagtatag caaaaaatga aagccctagc aagatatttg
    15601 accgaaaaat atctttatat ataatatatt gaaactggaa tagtacacct ctacttctaa
    15661 aacattgtta gaaatcgatt taactgtcct gattaatttg tcctattctt atttcatttt
    15721 attatagttt tcgatagcga tttattcttc caatacacga agaaaaacct ccacattcag
    15781 tggaggcaat ctgttttatc aatacaattt taagtcacga gggtcaactg ggaaggttgg
    15841 gttgtatgga ttgtgacgga gcttaaagtg tttgacatct tcaatggtct gagctccaga
    15901 caattgcata actgtcttca attccgcatt caagtgttca aagacttgac gcacaccgac
    15961 actaccaccg agagccaagc cataaataac agggcgacca atagctacca agtctgctcc
    16021 tgaagccaag gctttaaaga cgtgttgacc acgacgaaca ccagagtcaa agacaatcgg
    16081 cacacgtcta tcaactgctt ctgccacttc ttgaagcgag tcaaaggcag ctggtccacc
    16141 gtcgatttga cgaccaccgt ggttggttac ccagatacca gaagctcctg cagcaagcga
    16201 acgttcaacg tcctcacggc attgtggtcc cttgacatac acaggaagac cagagtattc
    16261 agcgataaat tctacatcgc gtggagacaa gcgttgttta gctgatttgt aaacaaagtc
    16321 cattgattta ccagcacctt ctggcaggta ttcttcaaca atcggcatgc caactgggaa
    16381 gacaaaacca ttacgcttat ccacttcacg attcccccct acagtagcat ctgccgtcaa
    16441 gacaatcgct ttataacctt catccttcac acggtccatg atgtggcggt tgataccgtc
    16501 atccttacta aagtaaaatt gaaaccaatg aggtgtccct tgaagggctt cagaaatctc
    16561 tggaaggtca acagtagagt aagaactggt tgtataaaga gaaccaaact catgcacacc
    16621 acgcgcagtc gccacttccc cctgttcatt tgccaattta tgagccgcaa caggtgccat
    16681 aatgattggc gaagatagtt tttcacctgc aaattcaatc tctgtacttg gattttcaac
    16741 atcgcaaagt gtatgaggaa cgatgagttt gtggttaaag gcgcggatat tctctcttaa
    16801 agtgaaagta tcttccgccc cactagcgat atagccaaat gctgctttag gaataacttg
    16861 ttgcgccatt ggctccaaat cataggtatt gatgaagtct acatgacctt ctgcattgct
    16921 tgttttgtat gacataaact gtcctcctcg attaagtaag cgtttgcttt ttactataca
    16981 actataataa ctcttttttc aatcattttc aagagttttg cttaaaaacc atcttatttt
    17041 ttcatacaat atactagccc tactttcctt aaactctaaa ccttagtcta tattaagtga
    17101 atcgttgaga ttttttgctg ccaggcattt gaactacttt tttatttgct gattctatct
    17161 actaatacta taaaaaacaa gtgaataaga caccagaaca tcctctaata ggacctatgg
    17221 acttatatca gtcccatata tactgtttaa gcaagatact atcctagttg acgctaactt
    17281 cctatcccac ttattaattt tttatttata gtgaatctga acaaatcaat tggggaatcc
    17341 aagtcaattt ctagtacttt ttgaaaagtt tcagcgtact atcgtaaaat gaaataaaac
    17401 atgcacaaat tgattaggga atttaaacca atttctaaca atgtcttaga aatcaaagtg
    17461 tactatttca atttcaatac actacacttc attttctcct taaattcagt ctctttttga
    17521 ataaaaaaat cctctggtaa gagccagagg ataagaattt atttcattgt tgggaagagc
    17581 aatacatcac ggatagttgt tgtatcagtg aggagcatgc agagacggtc gataccgatt
    17641 cccaaaccac ctgttggtgg cataccgtat tcaagagctt caatgtagtc atagtcgatt
    17701 cctgtcgctt catcatcacc aagttctttg gctttagctt gggcttcaaa acggctaagt
    17761 tggtcgattg ggtcgttgag ctcagtaaag gcattaccgt actccttagt catgataaag
    17821 agctcgaaac ggtcagtaaa gcgttggtct tcaggatttt tcttagcgag tggagataca
    17881 gctactggat gtccatagac aaaggttggt tggattaaag tttcttcaac aaactcttca
    17941 aagaaggcat tgatgatgtg accaacctca gtgtagtgtt tctcaactgg aactttcttc
    18001 tcagcagcga tagctttagc ttcttccaaa gtcatgtctt gccagaaatc gacaccagta
    18061 atttctctga tagcatccac catatgaaca cgcttaaatg gttcgttaat cttgatttca
    18121 gtaccttgat agttgactgg gccatcgccc ttaactgatt tagcagcatg ttggataatg
    18181 ccttccgtca agtccatgat atcttggaag tctgcataag cttggtaaac ttcgatagaa
    18241 gtgaactcag ggttatgagt agcatccatt ccttcgttac ggaagatacg cccaatttca
    18301 tagacacgtt ccataccacc cacgataagg cgttttaagt gaagctcagt cgcgatacga
    18361 agcaccatgt caatgttttg ggcattgtgg tgggtgataa atggacgggc agcagcacca
    18421 ccagcttcgt tgtgaagaac aggtgtttcc acttcaagga atcctttttg gtcaaggtaa
    18481 cgacggattt cagagatgat ttttgaacga gtgacaaaac gttcaaagct ttcacgatta
    18541 gaaatcaagt caaggtaacg tttacggtaa attgtttcaa cgtctgtcaa accatggaat
    18601 ttctcaggaa gaggacgaag agccttagac aagtgtgtga tgtgggttgc cttgatagag
    18661 agttctccca tatccgtacg catcacttca ccttcgacac caaggaagtc accaagatct
    18721 gcttttttga agatttcgta gttttcttca ccgacagcat ccttacgaac gtagatctga
    18781 atctggcctt cgcggtcttg aaggtgggca aaaccaactt ttcctttacc acgtttggtt
    18841 atcaagcgtc ctgcgatagt agctgtttcg tttttatcgt gtaattgttc tttatcgagg
    18901 ttggcatatt tatcttttaa ttcttgtgaa tttgcagtac gttcaaaacg ttttccgaaa
    18961 ggatcgattc cttgttcgcg gagcgcagcc attttttcac ggcgaacgat ctgctggtca
    19021 tttagttctt ccatatgttc tgtagacatg ggatcctcct agttttactc aaaattgaat
    19081 acgatgagtc attttttgcg atactcccat tttatcataa ataagcaaga aattcacgga
    19141 taatctttaa aaactaaaaa gaacctgacg ctaaaatcac tggaaagaag tgaaagtatc
    19201 tcccgcccca ctagcgatat agccaaatgc tgctttagga ataacttgtt gcgccattgg
    19261 ctccaaatca taggtattga tgaaatctac atgaccttct gcattgcttg ttttgtatga
    19321 cataaaatgt cctccttaat aagtaagcgt ttactttgta tattataaaa atatcttaac
    19381 tcttttttca aaacttttca aatattttgt ttggaaattt cagaaatttt atgtctatgg
    19441 taaaaaatcc ttataacggc aataaaaaat agatattatc caaagaagat tttaagtgct
    19501 acaataactg tattatttct agatgggagg ttctattttt ggattggtcc attgttgaac
    19561 aatatctacc actatatcaa aaggcattct ttctgacctt gcatattgca gtttggggaa
    19621 ttttgggatc ctttctgctc ggtttaatcg ttagtatcat ccgacattat cgaatccctg
    19681 ttttggcgca agtagcgaca gcctacattg aattgtcacg taatacgccc cttttgattc
    19741 aactcttctt tctctacttc ggtcttcccc gaatcggcat tgtcctatct tcagaagtct
    19801 gtgcaacgct tgggcttgtc tttttaggag gctcctatat ggcagaatct ttccgaagtg
    19861 ggctggaaac catcagtcaa acccagcagg agattggcct cgctattggt ctgacacctc
    19921 tacaggtctt tcgctatgtg gttcttccgc aagcaacagc ggtggcactc ccctccttta
    19981 gtgccaatgt cattttcctt atcaaggaaa cctctgtttt ctcagcagtg gctttggccg
    20041 acctcatgta cgtcgccaag gatttgattg gtctctacta tgagacagac attgcgctag
    20101 ctatgttggt agttgcttat ctgatcatgc tgctacccat ctcactggtc tttagctgga
    20161 tagaaagaag gacccgccat gcaggattcg ggaatccaag tactctttca aggaaataat
    20221 ctcctgagaa tcttacaggg gttgggcgtt acgattggga tatccatcct gtctgtcctc
    20281 ttatccatga tgttcggaac agtcatggga atcatcatga cctcccattc tagaatcata
    20341 cgatttttaa cacgattgta tctggacttt atccgtatca tgccccagct ggtgctactc
    20401 ttcatcgttt actttggctt ggctcgaaac tttaatatca atatctcagg tgagacttca
    20461 gctattatca tttttaccct ctggggaaca gctgaaatgg gagacttggt acgtggagct
    20521 atcacttctc tccctaaaca tcagtttgaa agtggatagg cactcggctt gactaatgtt
    20581 caactttact accacatcat catcccacaa gtcttaagaa gactgctacc gcaggctatc
    20641 aatcttgtca ctcggatgat taaaaccact tcattagttg ttttgattgg ggttgtggaa
    20701 gtgaccaaag ttggacaaca aatcatcgat agcaatcgcc tgaccatccc aactgcttca
    20761 ttttggattt atggaaccat tctagtctta tatttcgcag tttgctaccc tatttccaaa
    20821 ctatccactc acttagaaaa acattggaga aactaaatgt ctgaaactat cttagaaatc
    20881 aaggaactaa aaaaatcctt cggagacaat cccatcctcc aaggactttc tctagaaatc
    20941 aaaaaaggga agttgttgtc atcctagggc catctggttg tgggaaaagt accctccttc
    21001 gttgcctcaa cggcttagaa agtattcaag gtggagatat tcttctggat ggtcagtcta
    21061 tcgttgaaaa taaaaaagat tttcacctag ttcgccaaaa gattggcatg gtctttcaaa
    21121 gttatgaact ctttccccat ctggatgtct tacaaaacct catcctaggc cctatcaaag
    21181 ctcaaggaag ggacaagaaa gaagtaacgg aagaagcttt gcaattacta gagcgtgtcg
    21241 gtttgctgga taaacaacat agctttgccc gtcaattatc tggtggacag aagcaacgtg
    21301 ttgcaattgt ccgtgccctc ctaatgcatc cagaaatcat cctttttgac gaggtgactg
    21361 cttcgctgga tccagaaatg gtgcgtgagg tgctggaact tatcaatgat ttggcccaag
    21421 aaggccgtac catgatttta gtaacccacg aaatgcagtt tgcccaagcc attactgacc
    21481 ggattatctt cctcgaccaa gggaaaatcg ctgaagaagg aacagctcaa gccttcttta
    21541 ccaatctgca aaccaaacga gcccaggaat ttttaaacgt ctttgacttt agccaattcg
    21601 gctcatatct ataaaggaga ttcttatgaa actattcaaa ccactcttaa ctgttttagc
    21661 acttgccttt gcccttatct ttatcactgc ttgtagctca ggtggaaacg ctggttcatc
    21721 ctctggaaaa acaactgcca aagctcgcac tatcgatgaa atcaaaaaaa gcggtgaact
    21781 gcgaatcgcc gtgtttggag ataaaaaacc gtttggctac gttgacaatg atggttctta
    21841 ccaaggctac gctacgatat tgaactaggg aaccaactag ctcaagacct tggtgtcaag
    21901 gttaaataca tttcagtcga tgccgccaac cgtgcggaat acttgatttc aaacaaggta
    21961 gatattactc ttgctaactt tacagtaact gacgaacgta agaaacaagt tgattttgcc
    22021 cttccatata tgaaagtttc tctgggtgtc gtatcaccta agactggtct cattacagac
    22081 gtcaaacaac ttgaaggtaa aaccttaatt gtcacaaaag gaacgactgc tgagacttat
    22141 tttgaaaaga atcatccaga aatcaaactc caaaaatacg accaatacag tgactcttac
    22201 caagctcttc ttgacggacg tggagatgcc ttttcaactg acaatacgga agttctagct
    22261 tgggcgcttg aaaataaagg atttgaagta ggaattactt ccctcggtga tcccgatacc
    22321 attgcggcag cagttcaaaa agacaaccaa gaattgctag acttcatcaa taaagatatt
    22381 gaaaaattag gcaaggaaaa cttcttccac aaggcctatg aaaaaacact tcacccaacc
    22441 tacggtgacg ctgctaaagc agatgacctg gttgttgaag gtggccatta actcttaaaa
    22501 gggactggat tttaagctcc aatccctttt taagatttta cctataacat cctgagtcta
    22561 tctaagatgt tcaatctgaa cacagtgtac atactttatc ttctattgca tatactttat
    22621 cacataagat acgaatatcc tcttcactat gactagcaat caaaattgtt gtcccttttt
    22681 cactagagag ctttctaaac aatgttctca tattttctac acttgattta tccaaggcat
    22741 tcataggttc atctagtaaa agaatagagg gattctccat aattgcttga gcaatcccta
    22801 gctttttcct catacctagc gaataagttt taactttctg gtctttttgc tcatatagac
    22861 caactatttt cagtgtatca ttgatttcct gattaccaac tactcctcgt atgcttgcca
    22921 aatattgtaa attcttaaag ccactataat aatttataaa accaggttct tcaatcaaag
    22981 ctcccaaatt agctggaatt tttctctcag gaacaatatt ttccccattg attaacactt
    23041 ctccataaga cggactatat aaaccagcta ttaatttaaa caatacactt ttccctgagc
    23101 cattcgcacc agtaattcct ataatttccc cctgtttaca actaaagtta aggttttgaa
    23161 aaacacatgt cttttttaat ttcaactcaa tattttttaa tatgattatt tcattcattc
    23221 tataaacctc ctcttttgac gagtgaaata gaaaatgctt tgaaaaagaa agactaaaaa
    23281 tagcaactga agaaataaat ctcgtcctat atctccattc cctcgattca aaatataaaa
    23341 tagataatta gttcgatttc ctacaaatag accaccaaac acaatcatga gtaaaaagaa
    23401 actaacgcaa gcaaagttca tttgtacatt cgctcctagt gcgtataaca taaagcaaaa
    23461 caagactaac acacaagcat tcaaagaatc aactataaac aaaactccta tatcccagtt
    23521 tggtaactgt aacataaatt gaatcactag aacttttacc atgattaaaa tgagtccata
    23581 aagaaaacag gtccaaatct gatacctaat ccagagctta atagaagaaa atcgaatcac
    23641 ttccataaag aaatcggatg ctcttctacg atatacaact gctagaaaaa atgtatgaat
    23701 aataaaccaa tgaagcaacc atatagataa gactaaaaaa gagttttgac tcagattagg
    23761 cccttttaaa atttctataa caagtctatc atttccttct aaccaatacc ataatcctaa
    23821 acaaatcaat atccaaaaaa gaacataacc ccaaaagtac ttggtataga ttatctgatt
    23881 caacctccac atgtgactac ttaactttcc catttccaac ttttacactc tcctccagtt
    23941 tctatgaaca gaaaatacag tcaatggaat tatgatagat agtaatgtaa gccaataaat
    24001 caatgcatac ggattggaat ttaccatata ctgaaaaatt ggcaataatc caattatccc
    24061 attgtccaac tgataaatcc agaataagga ttctacaaat aaaaaagtaa acagaaatac
    24121 taagctcatg tttgattttt taaaccaaga aaaactgcta atagtaagta aggataaaaa
    24181 gaaatagtat gctatataag agaaaaaaaa tcctataaag aaactagcat tgtttgcaat
    24241 acttatacca taaaattctc ttaaaaaatc aacctccttt atctccaaag agaagctaaa
    24301 accattacta aatgcaatta gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt
    24361 actaagagct gctaatttga aactaaaact ggtaaagtgc ttaattgatt tcagacgaat
    24421 gcgacactcc aacctattaa aatagttatt catcaaataa aaaaagaaca atatatatgt
    24481 gaacggaaag caatatactc cagtcgtcat atcttgaagt aaaactaaga tccattctaa
    24541 tacatttgga tggattgaat attggcgaca gcgcaataaa tatactgtac tagataaaac
    24601 acaggatagc agtaatataa ataaaccaat actgataaaa aatctttttt gtaaaattga
    24661 acaaattgtt tcattatacg tagtcctctg aatgtagaaa aaatgtacca taaacaacca
    24721 aacaactaac aaataaaata aaagcaagat gcccactaac taaggaaaga ctgatatctt
    24781 tctgatatcc caaagctaat gttgtcacag gttctaagta agatagccct aaaatagccc
    24841 aaaaaatacc accaaccatc atataggcaa ctgggatgaa aatagctcct atttttttct
    24901 tcactagcaa agcactagct agtccaaaaa tagagaacac agtgccccaa actccatacc
    24961 agagagtcgt tacaagacta tagagaaact gattggaatc aaataattct tttaaggcac
    25021 cactataatc tccaatataa atttcctgat aaggagtcac taaaagatta attcctaata
    25081 ataataaata ggggagaaaa aagactagaa aagaagaaat aattacagta ctacccacaa
    25141 tagccagata cttcttttta gaaattcgac acaattgtgc tgttagaaaa tgactctcag
    25201 catcctctat tatctgacta gaatagggca gtgtacagat aagtgcagct actaggctaa
    25261 tcggtgaaaa tcctcgaata gaagaagcgg caaaaaaaat cgataaacct tcaattttat
    25321 aaataccatt gaaagcaagg aaatttccta aactcatgca aagaagggtc aaaaataaag
    25381 acatataaaa tcgaggtgat tgaacgactc gtacaagatt acaaatgaaa aattccatcc
    25441 ttactcctcc ttataataaa aatagggtgt agcattcttt tttcatgcta cacccacaat
    25501 caaccatctc taaggcttac tctgacaagt aagttaataa gaatctggat tccaagaacc
    25561 tgaagtatga attcttacat gatttccaaa ttgtggcgcc atagctaatc tagtaccaga
    25621 accaatataa ttgtcaccac ctccattata gtacatgaca atcctagagc cagaccccaa
    25681 tgaatatacc ggggtaatat ctgacccact ataggcgcta cgaatagagg tatttaacct
    25741 tttaccgcca ccagtgctgt cattattatt aattccagca gaggcgtttt ctttctcaag
    25801 ctcactagtt gtatccgaac cccaacgcgg cgacgttaaa tcataatctc caatctgtct
    25861 agctaaaact gtagggagaa acaaactaga tgcaattgta actacgcaaa aaaggaatat
    25921 atttttcttc ttttcatgac atcgtcctct taagaagtga taaacaagat agttgattga
    25981 tcaatttgat acatattaca ttttcattat atcaataaaa gaaagcgttg tcaattattt
    26041 tatttaaaat attgtcatat tttaaataaa atggtaaaag agactcggta gcctcgtctc
    26101 tctttatctt actgacctaa ccttcttgcc aattttcttg gtcttcttta aagcgtttta
    26161 gaagatcaag gccctctggc gtgatgtaac cttcttcttg ggctagatgg ataagctcgc
    26221 tatagtttga aagcgtcaca agtttaacac cagcatctgt aaagttctta tctgcttttg
    26281 gcaattggta gctgaaaatc gctacaactc caagtacatc tgctccttct cgcttggctg
    26341 ctgctacagc ttcaagaact gaaccacccg ttgaaataag gtcttcaacc actaccattt
    26401 tttgaccttg agctacgcga ccttcgattt gattaccagc tccgtggtct tttggtttgc
    26461 tacggatgta ggcaaaaggc aagtccatct tatcagcaat aatggctccg tgtggaatcc
    26521 ctgctgttgc agttcctgca atcacttcta cttcaggaaa ggcttctttg atagcttcca
    26581 caaaaccatt ttcaattagg gtacgagttt ctggataggc tagtgtcaca cgattatcag
    26641 tgtaaatcgg tgacttgata ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa
    26701 cggcttggat tttcaagagg tggctagcga tatctttagc aagtgtcatg gtattctcct
    26761 tttatttttc taatctagtt ctttaattcc agtcctgtgt ccattcatcc ttgatggcat
    26821 gataagctgc aacaggatcc tcagcttggg taatgggacg tcctactacg atatagtcac
    26881 tgccgatttg ataggcatca gcaggtgtca tgactcgttt ttgatctcca actgcaacac
    26941 cagctggacg aatccctggt gtcagacaga taaaatctgg attggtagcc tgcttgatga
    27001 cttgtacttc ctgagccgag caaacaacac catccaagcc agcttcagct gtcttcttgg
    27061 catagtgaat cacagactct tgcagactgg tttggatatt ttgaaactcc tgcatctgag
    27121 cttctgacgt tgatgtgagc tgagttacag cgatcaattt agcttgactt ccaagacctt
    27181 cacgcgcagc cttcatcatc tctacaccac cagccgcatg aacattggtc atatccacac
    27241 caagctgaga taggatcttc atggctgact tgactgtatt aggaatgtca tgaagtttga
    27301 gatccaaaaa gacactatga cccaaacctt ttaagtagga cacaatctca ggccccgctg
    27361 cgtaataaag ctccatccct accttgagat aaaggctttc ttctgctggg aaaagagcta
    27421 aaaattcctt gaccgcctca aaactaggaa aatcaagagc aatgattgaa cgatgttctc
    27481 gcataggttt ctccttttac ctttactagt gagagagtct ggccaacaga agccacgaaa
    27541 aaaggaacct gccaacagca aggttccacg aaaaatgggt agtctccacc ctttcaccgt
    27601 ctaaccttag ctgcctctct ggactgcttt aaaggttttc tattattcta ttatttctac
    27661 tagcacttgt caagtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag
    27721 cgacgcgatg aacgctgggt cgtttggttt cgattgctct cttcctcttg ttttttctgt
    27781 tcttcttctt gttttttctc agcttccttg gcctcttgtt tggctttttc ctcagcttcc
    27841 ataattaatt tatccgccac agtgtaactg taaattccag cttccatgtc aatcacactc
    27901 ggttctgaca attgtggctt aatcttactg taatatggca gtttcttact catttcagat
    27961 agaggaacca agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc
    28021 ttgcttgggg ctaattccac cttttggata gccgccttga gttctgggct aatttgagca
    28081 agttctgaga caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt
    28141 tctggtaaac tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga
    28201 taatgatttt caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg
    28261 aacttagttg gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc
    28321 tgcttttcat attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg
    28381 cctgaagcct gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct
    28441 ttcatggtcg cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga
    28501 aataaaatcg tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt
    28561 tcctttatag cctttttagc aagcttttta tcctgttcct ccttctcttt agactctgat
    28621 tcttctatct cttctttttc tttgtcagcc tctgaggatg ccactttttc ttcagactct
    28681 tccttagctg attctgaatc ttcctggtct gtttcactct cctggtcctg tttatcctct
    28741 gacttctcag attcttctcc cattcgagct tgtctttcct tttccttctc ctcagctaga
    28801 gccgcctctt cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat
    28861 aactctttca attcttcgag ggtttctttg tcctcatttt tcttatcttt tgacatttac
    28921 tttccttatg ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc
    28981 ttagaagctt tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc
    29041 tcttccaaac tatccaaggt caaatcgctt tcttgaaggt cttctgcata gccttttttt
    29101 acaaagtaag ctgcattttc aatctggtca ccacgactag cttcacgacc aagcggcaca
    29161 atgacatgca attttgctat cgccaagagc tcaaaaatcg tattggcacc acctcgtgtc
    29221 acaacaatat cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga
    29281 aaaagatttt gcctcaactc attcagacta gaatctccag ttagattgat aatattgtag
    29341 cgctctgtta gttctttctt atggtctgtc accaattggt taaagacacg agcgcctgca
    29401 gaaccgccga caaacaatac agttggcaat ttgggattaa agtgggtttg aatatccacc
    29461 aattcatctg gttctggagt gtttttgtcc gaaaccttgg tcaccgctcc cacatgctcg
    29521 accttagcca aactcgaagc ttgttcaaag gttgaataca tcttagtcgc aaatttatag
    29581 gcgattttat tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct
    29641 gacacacgcg cagcgataac aggcggtact gagacaaagc ccccctttga aaaaagggtc
    29701 tgtggacgca gtcgcaacat gataaagagc gattggacga ttccccagcc aactttgaag
    29761 acgtccagca tattttgcca agagaaatag cgacgcaatt tcccagtcgc aatagaatgg
    29821 aaggtgacat ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg
    29881 atatagtgga cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta
    29941 acgtgtccaa ccgtcccccc acctgtaaag acaatttttt tcatatttta ttcttttaac
    30001 tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag
    30061 ctggcattgg caggactaag aagaaccaca tctccttgag tcgcaagttc ataggcctta
    30121 cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc
    30181 cgtttgacac gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct
    30241 ggcaccaatt cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg
    30301 ctgttgtcaa atcctgataa ggctttttga gtagccaaga tattagttga tttactgtcg
    30361 ttatagaatt taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg
    30421 aaggctgaaa gagtttcctt gatggtttga ttgtccacat cacgaagctt ggctacagca
    30481 atagtcgcaa gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc
    30541 atgactactt caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt
    30601 tcaagtgttg aaaatggtac aacagtggct tctgtcttgg aagtcaagtc ttttgccaag
    30661 tcttgattaa agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac
    30721 ttggctgcta catattccga aaatgaccca tggtagtcga tatgagttgg catgaggttg
    30781 gtaataaccg caatctctgg atggaattct tgaacaccca tgagttggaa agaagaaagt
    30841 tccataacaa gcgtgtcctt atctgatgct atttgagcaa cctgactagc tggatagccg
    30901 atattccctg ataaaagacc atgttgccca gcagcagtca aaacttcccc aatcatagtc
    30961 gttgtggttg tcttaccgtt cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa
    31021 taagccaatt ccacctcagt caagactgga attcccttgg ccaaagcctt ttcaatcatg
    31081 ggattgttgt aggggatacc tggatttttc accataaggg caaactcttc atccaagagt
    31141 tccaaaggat ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgggcagct
    31201 ggattgtcct cgaaaggttt cccatcattt actgtcacaa tggcacctag cttgtccaac
    31261 aaacgagctg cagattcacc agacttggcc aagcctaaaa caaggacttt cttattttta
    31321 aattgatcta ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt
    31381 tatggaaata aaaaagccac aaagtgtgtt tgtgactctt tcttctaact gaatcttacc
    31441 atatcatcta tgtgataaat cggtaactcg aatgacctga tccacttgct cccaaatcag
    31501 aggattatgg gtcgcaataa taatggtccg attcggattt tttaaagatt ctaggatgga
    31561 aagtaattcc tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa
    31621 aggtggatcc tttaaaatta tcttcgctag tgcaacacgt tgtgcttctc ctcctgataa
    31681 ctcaaatata ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt
    31741 catcaaagag attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt
    31801 ctctttgacg gtttggcttt caattaagcc aaaatcttga aataagtatc ctaagtaatc
    31861 tctaaagaaa acagaaggct taatgtcctt aagagaagtg ccatcatata tgatttgccc
    31921 tttgtcatat ggctctaatc gtccaatcat attcaagagt gttgtcttac cacagccact
    31981 tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga agattcgtat ctgaaaatag
    32041 ctgacggctt ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca
    32101 taattgtcat agaaacacga gattctttct gcgcttgacg gtaaagcgtc aaaactgcac
    32161 taactagaaa gaccaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa
    32221 agagactagc accaaataca aaactggcaa attggctaac catatactga gcatgtgttt
    32281 caaaaaatcg taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat
    32341 atagaagatt gacagaataa aagagtaaca aggaactggc tattccaaca atagctccta
    32401 agattaaagt tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc
    32461 cttctttaag ataggatact tgctcataaa ttccagcttt cttcaagagt tctagcccac
    32521 tctcatatcc tttgataaag agttgttttc cagcattgat agaccaacta gataaggata
    32581 taaaactatc acctgtagaa gtcggcgtga atacaactaa aatcggatca gtcaaatact
    32641 gagtagatac gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat
    32701 aactaacgtg cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc
    32761 cataataact caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat
    32821 gttctgggag caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct
    32881 cagcatctac cacgaccttt tccttgtcca aataactggg actaacatag agcgtattag
    32941 catctggact ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa
    33001 aatggagcag attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa
    33061 aggcatacca cttgctctga ttttctgtat cttttcctct atcacctaag ccaaaggaaa
    33121 tctggtaata gtctgctctg tcctgccatg cttgttttga aatttcaagt tctttcaatc
    33181 gttggtaaga cgtcaaacct gtcttaacag cgtagcctac tgtaaaaaca gctactaact
    33241 gacacaatag ggttaaagcc atcaagcgtt taaggggtaa tcttccctta ataacgggaa
    33301 ctaatgcttt gtaactcaaa ctcattaggt aaaggagcat tagtaaaatt gaaatcgcca
    33361 ataaaaacaa cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa
    33421 acaaaccttg actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa
    33481 ggagccactt gatatcagta gataaacccc aattattcac ccctaatcta aaaaccatcc
    33541 agaatccttg ccttagctta gatcctggat ggtttctttt ttcacccaat gggtgttttt
    33601 tactagacaa aaaagagttt cccctttatg gtataagtgt agaaaaaaac acaaaaagaa
    33661 aggaaactca tatgaacagt ttaccaaatc atcacttcca aaacaagtct ttttaccaac
    33721 tatctttcga tggaggtcat ttaacccagt atggtggtct tatctttttt caggaacttt
    33781 tttcccagtt gaaactaaaa gagcggattt ctaagtattt agtaacgaat gaccaacgcc
    33841 gctactgtcg ttattcggat tcagatatcc ttgtccagtt cctctttcaa ctgttaacag
    33901 gctatggaac ggactatgct tgtaaagaat tgtcagctga tgtctacttt ccaaaattgt
    33961 tggaaggagg gcagcttgct tcacagccaa ccttatcccg ttttctttcc agaactgacg
    34021 aggaaacagt ccatagtttg cgatgcctca accttgaatt ggtcgaattc tttttacagt
    34081 ttcaccagct aaaccaactc attgtagata tcgattctac ccatttcaca acttatggca
    34141 agcaagaagg tgttgcttat aacgcccact atcgtgctca tggctatcat cctctttatg
    34201 ctttcgaggg gaagacaggt tattgtttca atgcccagct tcgtcctggt aatcgttatt
    34261 gttctgaaga ggcagacagc tttatcacac ctgttttaga acggtttaat caacttctct
    34321 ttcgaatgga tagtggcttt gcgaccccaa aattatacga tttaattgaa aaaacagggc
    34381 aatactacct cataaaactc aagaaaaata ctgttctgag ccgtcttgga gacctttccc
    34441 tcccttgccc acaggatgag aacttaacca tcttgcccca ctccgcctac tcagaaactc
    34501 tctatcaagc aggatcttgg tcgcacaagc gtcgtgtctg ccagttctct gaacgaaaag
    34561 aaggaaactt gttctacgat gttatttctc tcgttacaaa tatgacgagt ggaacaagcc
    34621 aagaccagtt tcagctttat cgtggacgtg gtcaagccga gaatttcatc aaggagatga
    34681 aggagggatt ttttggcgat aaaacggata gttcaacctt aatcaaaaac gaagttcgta
    34741 tgatgatgag ctgtatcgcc tacaatctct atcttttttt caaacatcta gctggaggtg
    34801 acttccaaac tttaacaatc aaacgcttcc gccatctttt tcttcacgtg gtgggaaaat
    34861 gtgttcgaac aggacgcaag cagctcctca aattgtctag tctctatgcc tattccgaat
    34921 tgttttcagc actttattct aggattagaa aagtcaacct gaatcttcct gttccttatg
    34981 aaccacctgg aagaaaagcg tcgttaatga tgcattaaag aacagtcgag atgaaaaaat
    35041 cgtgtgacgc accaagggag gagtctgccc ttttgaggaa atctagcgag gaaaaacgat
    35101 actggaacag cagaaagtaa aactgacctc atgaggagga agaaagtggc tcatgaggtc
    35161 aggggttttg taagttacat ctagttgaga gaggtatgaa tgatttggga taaagaatcc
    35221 cccatgatgg ataagagagt ctgaccagaa aagagtttta tacctgctgc tctcatttcc
    35281 ttaatccgag tgataatcac taaagcaaag aaagataagc caaatattgc taaactaatt
    35341 aaaataaggg gatttagtaa tattcgaaaa gcaagaaaat agggcggtat ctttcggtca
    35401 gcacttgctt tataacccaa atctcctaat ttatcggcaa gcttttcttt cgtcaaggag
    35461 cctgacaaaa ggagataact atttagcgga tcactacgtt cacgactttc ttggctagct
    35521 tcttggaatt cttttggtaa agttccctga ccataagttg cataagtaaa gtgagtcgtc
    35581 ccatccttac tcggctctac aattcttcta gctattaaac tctgttctga gtttgcaaaa
    35641 ttctccaatt cctgttcaaa tacctcacgc gtcggttcct gagtatcttt tttgacacga
    35701 agtaaagaaa cggaatcata gcttgcatat aaatattgtg gcgcacgtaa gacaataatc
    35761 caagcaagga agaagctgag aaaaaaagtt gataataata tgaatagttt cttcatagta
    35821 gactccttgt aaacaaaatt ccccctgtaa tttcttacaa ggggaacgat ttaaatcaat
    35881 gaacgattag tcataatcac agtaaaatgc tacttgttct ccccatttag tccaaatcca
    35941 tgcataggag gtttttccag caggagcttc tcctttatca gaatgaccat cccatctgct
    36001 cacgatggat gaataatgat attttttacc atgatagtaa tttgaaaaag cctaaccacc
    36061 tcctgaacct tctccatatg tccatactcc tccatctgga tattatacag cagctgatgc
    36121 agctcccaat aatgtaaaac ttgaaataag agctagagca agtaatctat gttttttcgt
    36181 tttcatttta ttttttcttt caaaaaaatc acaccttgag caacaatgca acaaaataaa
    36241 tcctcctctc tcttttattg aaaccgcttt cttgtgtgat aagaataaca tttttattat
    36301 ttgttgtcaa ggaaaaaatc gaatttttta gatgttttac tatattatct ctatgaataa
    36361 tattatatag tagttttatt tcaaaataat atgcaaccag tactaaccaa atataaaata
    36421 gatgccatta acgaatttta ttcaagtttt tcccattcat actatacaag caaaagagat
    36481 ggtgttaact aaaaagcaat tcaaactatt ataaaattcc tagcaaaaag agagccgaaa
    36541 ctctcttttt tatcttcttt tacttttttt gactggcatg agtgtgatgt ctctaacact
    36601 aaagtaagct aggatcaaca tggctattgc taggaatatt tctgttggta attgaaaaat
    36661 tttcagaaaa gatagaacca ataaaatcaa gagtgccact aaaatacata ccatagcgac
    36721 gatattgact gtccctttaa tgctttctgg tgtcgcaaat acatagagta ggagcagtaa
    36781 aattcctagg actaaataga ccatctttct ctctttctag ctcttattca gctgattttt
    36841 tcttcttatt agctttctca cgctctgctt tgttaaggat ttgtttacgc aaacggatag
    36901 actcaggcgt tacttccatg tactcatcgt cgttcaagaa ctcaagagac tcttcaagtg
    36961 tcaagatacg aggcgtcttg ataacagctg tttggtcctt agtagctgaa cgaacgttgg
    37021 tcatttgttt tgccttcgtg atgttaactg tcaagtcatt ttcacgagag ttttcgccga
    37081 tgatcattcc ttcataaacc tcagtacctg ggttgacaaa gatcgtacca cgttcttcga
    37141 tagacatgat tgagtaagtt gtagccttac cagcatcgat agaaacaagg gcaccacggt
    37201 gacgtccacc aatttcccct ggaatcaatg gcaagtattg gtcgaaggta tggttcatga
    37261 taccgtaacc acgagtcatt gacaagaact cagttgagta tccaatcaaa ccacgcgctg
    37321 gaacaaggaa gaccaaacga gtttgaccat taccagttga aatcatatcc aacatttcac
    37381 ctttacgttc agaaaggctt tggataacag acccttggta ttcttctgga gtgtcgattt
    37441 gtacacgttc aaatggttca catttaacac cgtcgatttc ttttacgata acttctggac
    37501 gagatacttg aagttcatag ccctcacgac gcattgtttc gataaggatt gacaagtgca
    37561 attctccacg tcctgaaaca gtccatttat ctggtgaatc agttgggtca acacgaaggg
    37621 aaacgtctgt ttgcaattct gcctgcaagc gttcttccac cttacgagaa gttacccatt
    37681 taccttcttt accagcaaat ggtgagttgt tgaccaagaa agtcatttga agagttggct
    37741 catcgatgtg taggattgga agagcttcta ctgcatctgt cggagtgatg gtttcaccga
    37801 caaagatgtc ttccatacct gaaacggcaa tcaagtcacc cgctttggct tcttggattt
    37861 cacgacgttc caaaccaaag aaaccgaaga gttttgtaac acggaagttt ttagttgtac
    37921 cgtcaagttt agaaagggta acttggtccc caaccttaac tgtaccacgg aagacacgac
    37981 cgataccgat acgtccaacg aagtcattgt agtccaaaag tgacacttgg aactgcaaag
    38041 gctcatctga gttatctact ggagctggga tatggtcgat aatcgtgtca aagattggtg
    38101 ccatagtcgc ttcttggtca gctggatcat ctgacaatga agaagttccg ttgatcgctg
    38161 aagcataaac cactgggaaa tcaagctggt cgtcatctgc accaagctcg atgaaaagtt
    38221 ccaagacttc atccactact tctgctggac gagctgatgg cttatcgatt ttgttaacaa
    38281 ccacgattgg gacaaggtct tgttccaagg cttttttcaa tacgaaacga gtttgtggca
    38341 tggttccttc ataggcatct acgaccaaga caacaccgtc aaccattttc atgatacgct
    38401 caacttctcc accaaagtcc gcgtgtcctg gtgtgtccat aatgttgata cgagttccgt
    38461 tgtaagcaac ggcagtattt ttagcaagga tggtgattcc acgctctttt tcgatatcgt
    38521 ttgagtccat agcacgctct gccaattcag tacgtgcatc aagcgtttct gattgtttca
    38581 ataattcgtc aaccagggtt gttttaccgt ggtcaacgtg ggcgataatc gcaatgttac
    38641 ggatatcttc tcttaatttt gtcatgattt cctctataat attcaaaatt tattttctaa
    38701 ctgaacgatt ataccataat ttcaaataaa taacataact caagcaagtg taaatgtttt
    38761 cactccgctt ttcttttcac gtcaagcctt ttcaaagcaa gcgacttatg ataagatagg
    38821 cacagtatgc gtttagataa tttattagcc caagaaaaag ttagccgaaa ggccatgaag
    38881 caagcactcc tcagagggga aattctagtc gatggttgcc cagcccgatc cctagctcaa
    38941 aatatcgata caggactaca agaactcctt tttcaggatc gaatcattca aggctatgaa
    39001 cacacctatc ttatgcttca taaacctgct ggtgtcgtta cagccaacaa agacaaggaa
    39061 cttccgaccg tcatggacct gcttccatct gacatccagt ctgacaagct ctatgccgtt
    39121 ggccgactgg accgagatac aacgggactc ctcctcttga ccgataacgg tcccttgggc
    39181 tttcagctcc tccatcccca atatcatgtc gataagactt accaagtcca ggttaatgga
    39241 cttctaacac ctgaccatat ccaagccttt caaaagggaa ttgtcttttt agatggtact
    39301 gtctgtaaac ccgcaaaact agagattcta tctgcaagtc cctccctcag tcaagcctct
    39361 atcaccattt cagaaggaaa atttcatcaa atcaagaaaa tgttcctctc ggttggtgtt
    39421 aaggtgacta gcctcaaaag aatccaattt ggggacttca cattgaaccc agatttagca
    39481 gaaggtaact accgcccttt gaaccaaaaa gagttacaaa tcattaaaaa ctatttagag
    39541 atgagtcgat aaaacaaaaa aagctttaaa actaaagctt ttttctttta tttaccgaaa
    39601 aattaaggcg attgctacaa tccagttaac tacagaaatc acaattccta agatattaag
    39661 aatcttttct attttatagt ctaattgtga ctctttttgg tatgaaatag ccaagaccaa
    39721 tcctatgata cccaaaatca ggcctacaat tggaaataac aaaccaagaa taatcgacaa
    39781 gatacccaca aaaagtggat ttttcttctt ttctttcatg ttctaagaac tccttaaatt
    39841 ttatacaaat taattatact ataaaacaat atcttcatcc tatcattcga ctaatttgga
    39901 aataaggtta gctagtcttc actttccctt tccaagaatc caagccataa gaaaggatat
    39961 aaatctcaga aaaaccttgt tttttcaagt aaagagctgc atttgtaact cgttgcgcac
    40021 gttggttttc gtagagaagg acaggtttat ctttacgaag ggctgcaaga ctagttttca
    40081 actgacttga aggaatattg cgtgcaccaa ggatatgttt tctgtggaat tctgctgggt
    40141 cgcgcaaatc aatcaattga cccgtacgaa tcaaggcttc aaactcctca ttgtccacaa
    40201 ttttagccgc acggcgaata cgaagatagt taaagcccat ccacgccaac attgctagta
    40261 taagtgccca caaaatccaa gtaaccatta gttcttttct ccatttttct caatataatc
    40321 caattctacc ttgtgctctc tgcgaagaac tgcttctgcc tctagatagt ctaatttatc
    40381 catcaaccct gcatcgtaaa tccgagatag ttccaacttc atcagttcaa tatcatataa
    40441 tcgttttccc atgtaaacaa taataccaaa tcgtttgagg aattgctgca catcatagaa
    40501 tgttttcata agactcattc tagcaaaatt ttgtgttttt ttcaagaaga gactcacaca
    40561 atgctcctta ttttcctatc ttctttagcg attctaaggc aagtatggta caataaaaac
    40621 atgagaattc aacaattaca ttatattatc aaaatcgtcg aaactggctc catgaatgag
    40681 gcagccaagc aactctttat cactcagcca agtctctcca atgcagtgcg agatttggaa
    40741 aatgaaatgg gcattgagat ctttatccgc aatcccaagg gaatcacctt gacccgtgat
    40801 gggatggagt ttctctctta tgcccgtcag gttgtcgagc agacccagct tctggaggaa
    40861 cgctataaaa atcctgtcgc ccaccgcgaa ctctttagcg tttcgtctca acactatgcc
    40921 tttgtggtca atgcctttgt ctctttgctc aagaaaagcg atatggagaa atacgaactc
    40981 ttccttcgtg aaactcggac ttgggagatt atcgacgacg tcaagaactt ccgcagtgag
    41041 gtcggggtcc tcttcttaaa cagttacaac cgtgatgttt taaccaagat gctggatgac
    41101 aatcacctgc tagcccacca tctcttcaca gcgcaaccgc atatctttgt cagcaagacc
    41161 aaccctctgg caaagaaaga caaggtgaaa ctgtctgatt tggagaattt cccttacctc
    41221 agctatgacc aagggacgca caactccttc tacttttcag aagagattct ttctcaagaa
    41281 caccacaaga aatccattgt ggtcagtgac cgtgccaccc tctttaatct cttgattggt
    41341 ttggatggtt ataccattgc gacagggatt ttgaacagca acctaaacgg agacaatatc
    41401 gtttctatcc cactggatat tgatgacccg attgagctgg tctatatcca gcatgagaaa
    41461 accagcctat ctaagatggg cgaacgcttt atcgactatc tactagaaga agttcagttt
    41521 gatagttgag aaatgataag aaccaatatg taggctagca acaacctgca cattggttct
    41581 ttttacttat aattaaaagt ttcccctgcc aacttatcag ctagcttggg aaagagagta
    41641 taaaacttat gggctaggtt caacaaaatc gggagattga gttctcgttt atttttgcct
    41701 ataatcttga caatcttttt agccactgca tctgcctcta agaggaagcg gtcaaccgat
    41761 ttaagataag ttccatctgg gtcagcttgg tcaaaaaatc ctgttcggat tggacctgga
    41821 ttgactgttg tcacatagac tccatagggc ataagttcga gtcgcagagc atttgaaaaa
    41881 ccaatagccg caaacttggt cgctgagtaa agactagact tgccagtagc tattagacct
    41941 gccatgctga cgatgttgat gatatgccct ttgctgcttt ccttcatacg agccgcaagg
    42001 tgacgagaca gattcatcag ggcaaaggta ttgacctcaa acatctggtg aatatcttta
    42061 tcagcaatct ggtcaaatcc ctcaaaaatc ccgtaaccag cgttgttaat caagacatca
    42121 atcttgccat agcggagata aagatcagtt accagagctt ctagggctga atcgtcggta
    42181 atatcaattt caatcaattc tgcatgggaa taatttccgt agagttgggc taatttttcc
    42241 ttatttctac caagcaagat gagttgatca ttgggcagga gtttgaccat ttcttgagct
    42301 agaccaccgc tagctccggt aatgagaata gtaggcatac ttatcctttc tgtgactgct
    42361 agatttccac ttcttccaag tctttgacca catggacatt ttcaaaaatt gtggcagcgt
    42421 ctttcttgag tttgcttata tcttttgaga ggaaacgggc actgatatgg ttgagtagga
    42481 ggcgtttggc acctgcttct accgctactt gtgcagcttg catattagtt gagtgaccat
    42541 ggttacgagc aattttttca tcacccttgc cataagtgga ctcatgaact aggacatctg
    42601 cattgacagc cagacgcaca ctggcatccg tttttcgagt gtctcctaaa atagtgataa
    42661 tcttacctgg acgtggcgct gagatatagt ctgctgcctt gatttcagtt ccgtcttcca
    42721 aaacaagatc ctggccgttt ttgattttac caaaaagcgg gccgaacgga acaccagcag
    42781 ccttgagttt tttagcatcc agcgtccctt ctagatcctt ttgcatgaca cgatagccaa
    42841 cacagaaaat agtgtggtcc agctcctctg catacacagt gaatttatcg gtttcaagaa
    42901 ttttacccag agaatcttgg tcaaactcat ggaaatgaat gcggtagggc agacgagaac
    42961 ctgacacacg aaggctggtt aagacaaatg acttgattcc ttgaggtccg tagatttcca
    43021 aatctgtctg ctcttcattg gcctgaaagg cacggctaga aaggaaacct ggcaaaccaa
    43081 aaatgtggtc tccatgcaga tgggtaataa agattttgct gaccttacgt ggtcgaattg
    43141 tggtttccag aatgcgattt tgcgtacctt ctccacagtc aaagagccaa acttcgttaa
    43201 tctcatccaa aagtttcagg gcgagacttg aaacgttgcg ggctttagag ggctgaccag
    43261 cccccgttcc taaaaattga atatccattc gatactttct aattaatcaa tatataacat
    43321 ggctgtgcgg ttttccgatc ggaaatagcg tttgccagaa aaagcagcag cttcttgcaa
    43381 taaatcctct tggctgtagc ctttgagacg ttttcgacca tcagccaatc tttccaaatc
    43441 agtcaaagct gtgagacttt ctaggctgac aacttcctcg tcctcgacag gcttcatgta
    43501 aatcttacca gactcttcaa agactaattg atgggggaaa atttgcgcaa tttcaaagag
    43561 caagtcatcc gagattttct cctcattttc agagaaaatc cgaccaaagc cgtcactctc
    43621 ataacaaaaa ccaaaggatt taccagacag attaagccga ataaaagact tattttctag
    43681 ggtgaaactt ggctcagtat tgtaaagatt cagttcctga ctgagttctg caaaataatc
    43741 cgtcgcagcc tgaggacttt ttttctgata gagttctgca aagtaggcat taacaacact
    43801 tggcggaggt gtaataagtg ttaactgctc ctgctctgtc ttaccagcta gaagctgatc
    43861 cagatagacc ttgtccagac ttgtataacc tccatacttt agagccaaag ttttaatatc
    43921 agtcataaaa ttcttctaac ctccatttat ttttctcgga aatgtagcct gtaatcactt
    43981 cgccgtcttc ctgataatca cgttcttcca gaattgcaac actctctaaa tcatgaatct
    44041 tgtaggactt tgaaaaaggc actcgcaggg taaatgcttc aaaaatttcc ttaatcttat
    44101 ctagcaataa tgcttgcaag ttttcacgac tgtcctcaga cttggcagaa atgagggtat
    44161 atggcgtttg agtaggcgtg aaatcctcca ccaaatccgc tttattataa agcgtcaagt
    44221 gaggaatatc ttccatgtcc aggtctttca tgatggagag aaccgttttt tcatgctcct
    44281 cgtggtaagg attgctagca tcgataacat gaaccagaag gtccacatgc ttgctttctt
    44341 ccaaggttga cttgaaactg gacaccaact ctgtcggcaa atcttggata aagccaacgg
    44401 tatctgtcaa agttacttgg agattgcctc ctagatgaat actcttggtt gtcgcatcca
    44461 gagtcgcaaa gagctcatct gcttcatact gggtcttact ggtcaagatg ttcatgatag
    44521 ttgatttccc agcattggta taaccaatca aaccaatctt aaaggtgcta gactccaaac
    44581 gtttttctct gacagtcgca cgatttttct caaccacctt aagctggcgc tcgatatccg
    44641 tgatttgatt gcgaacgcta cgacggttca gctccagttg gctttcacca ggaccacggg
    44701 aaccaattcc ccctgcctga cggctgagca taatcccctg accaaccaag cgaggcaaga
    44761 ggtatttgag ttgggctagg tggacttgga gcttcccttc atggcttcga gcccgcatgg
    44821 caaagatatc caaaatcaac tgcatacggt caatgacctt aacaccgaga acttcctcta
    44881 gattgacatt ctgccttggg gtcagacggt tgttgacgat gacagtagtg atttcttctg
    44941 catccaccat aagcgcaatc tcttccaact taccagagcc gacgaaggtc ttggaatcat
    45001 atttttcacg tttttgtctg tagctatcta caacgactgc ccctgccgtt ttcgctaaac
    45061 tagccaattc ttccatggag aggtcaaaac tgtccatacc ctgcaattcc acaccaatca
    45121 gcaggacccg ctcctctttt ttctccgttt caatcatcta aaaactcctc tatctggctt
    45181 aaaatgcggt cttgtacacc agattctcca atctgataaa aggtgacctg catgcgatta
    45241 cggaaccagg tcagctgacg cttggcaaaa cgacgagtag cctgtttgag actctcacga
    45301 gcttcctcca aggtctgctc tctacggaaa taaggaaaga gttccttata gccaattcct
    45361 ttagcagcct gtacattagg ggaatggtca aacagccact tggcctcatc caaaagccca
    45421 gcctcaaaca tcaaatccac tcgatggttg atacgctcat aaagttgact acgttcatca
    45481 tccaagcaga taatcagcgg ttcatacaag gtctcttgat tttccaaatc ctgaccaaaa
    45541 tgggcaattt ctaaggcacg catagcacga cgacgattaa actggggaat ctcaaggcct
    45601 gcttgctcca ccaaatgggc taattcctca tctgaatatg gctccaaact agctcgataa
    45661 gctaaaatct cctcatgagg agtctcccca cctaggtggt aaccttctag caagctctgg
    45721 atataaagtc cagtcccacc ggcgataatg gctagcttgc cacggctgtg aatatcctca
    45781 atagtcatct tagcttctga aacaaaatca aaagccgagt aagactcggt tatctctcta
    45841 acatcgatta aatgatgaag aacagctgcc tgctcttctg gactagcctt ggccgtccca
    45901 atatcaagtc ctcgatagac ttgctggcta tctccactaa ccacttcgcc attaaaacgc
    45961 tttgcaactt caatagctag agccgtcttt ccaacagcag tcggtccaac aatcacaatt
    46021 atttttgttt tcatcttttt tccttgaaaa attcccattt tttcgttact attattataa
    46081 cacaaaaagg tcagtcagaa aaatgtgacc tcttgaggag gctggctgat tgagaatata
    46141 aaggaggaag actcatggct aaaggattcg ctaaaggtct tgtaacaggt gtcgcaggaa
    46201 ctgtcgctgc cgttgcaggt gcagtatacg catttaaaaa gaaagtaatc gaaccagaag
    46261 agcaaaaagc agctttcatc gaagaaaacc gtaaaaaagc agctcgtcgc cgcgtatcac
    46321 gttaagaaac aaaagaagtt gggattattc tcaacttctt ttttctattc ttttaaatag
    46381 ctaggtcaaa cttcaactgt ggcttaacag ggtcataatc caccaactca aaatcttctg
    46441 ctttgatatc aaagaaatta gtcccatcag gaacatttaa aaccaagcgt ggttggcagt
    46501 ttgacggctc ccgacggagc aattcctgag cttgttcaaa ttgattatca tagatatgga
    46561 ggttgttgat gaagtagaag aacttcccaa ccttccagcc aaaatgtttg gcaatcatca
    46621 tctgcaaagc cacatactgc atagcgttga tgtggtgggc caccagcata tcattggagc
    46681 gctgggtcaa ggtcgcatcc agatagattt ccccatcaac acgccgaaca tcaaacatgg
    46741 tctgaaaggc gcacgggagc agcccatctg tttcttcgaa agcttggtaa tcccagagag
    46801 aaataatatt gcggcggttc caaggattgg ttttcaactg tttgagaagc ttattgataa
    46861 tgtcgtgttt cttaacaacg gcaccatagc gctcaccaat ggttcccgtg tctccaactt
    46921 cccagtcatt ccagtagtga acattgtact tgtcattaag cacttctaag ctatttgact
    46981 ggtcttggta aatccagaga acttctttga tggcggattt gattgcaatg ggacgcaagg
    47041 ttgtgatagg aaattctcct ttagataagt cgtactcgga aaaggcacca gttacatact
    47101 tggaattagc aacagtccca tccttgtact taggacgagc ctgctctgag aaaacacctt
    47161 cctttagaat gcgttcaata ttctctttaa aaatcgtatc tgcttttgtc atttactctc
    47221 acctcattca ttgtcctaac tagtatagca taaaaaataa aagaggaaca ttactaactc
    47281 taggttagca ttttcctctc tcattatctt attgcaatac aagtgatgct gctccgataa
    47341 ctccagcgtc atttcctaga gttgcaagag ctaatttagt agatgtgcgt acttgtggga
    47401 aagtattttc gtcatagact ttttgaacac cttgtagaag gaattctccc gcagctgaca
    47461 caccaccacc gatgacgatt gttgatgggt ttaggattga accaatgtta gcacaagcga
    47521 ttcccaagta acgtgagaag ttacggtaaa caatcaaagc aaggtcgtct ccttcttttg
    47581 cgagatcaaa gacagtctta gcagttactt cttctccgtt atcaatcaag cgtttcaagg
    47641 ctgcatcgcc ttcgtattca tcggcatagc gacgagtcaa gttgacaatt cctgttgcag
    47701 aagcgactgt ctcaagacag cctttcttac cgcaagtaca tgagattggc tggtcaaagt
    47761 caacagtgat gtgaccaagc tcacctgctg caccagcaac accgtgaagc aatttgcctt
    47821 ctgcgacgat accgccacca acaccagtac cgagtgtcat aaagacaaca tctggttggt
    47881 tatcaccagc acccatccag cgctcaccaa gagctgctac gttggcatca ttatcgatga
    47941 aaaatggaat gcccaaagat ttttcaatct tttgtttgat tggttgaagg gttttccagt
    48001 tcaagttgta ggcaccgata acagtccctt tgtcacggtc aaccacacct ggtgatccca
    48061 ttccaatgcc ttggaagtcc gctgctgcca atccaagcaa gtccaaacga tgttgaatag
    48121 actcaatcat atcatcaacg atatgacttc cctcatccaa aatgttggtc ttgattgacc
    48181 attttccttg gatttctcct gctgttgtta agattgcaaa tttgatagaa gttccaccaa
    48241 ggtcaatccc aataatcttt tgactcatca tattctcctt tttcattgtg tagtaattga
    48301 aaatgcttac agtactagta tatcaaaatc cattcactta tgcaaaggtt tgcgtaaatg
    48361 aattataagg aattttttcg cctaccagta tctgttaatc atctaaatga tcaatggcat
    48421 attgagctgc atcatttgaa aatttatcaa aatcagaagt taattgtcta tacatacgtt
    48481 tttttgacat atggaataac gaattataac tttttgcttt tcctaaagca gcagaatatt
    48541 cactattgct atcattacta gaagaagctg tacttgcttg accttccttc caaactccgt
    48601 cagcaccaac ataataacgt ccaccatcaa cccattcatt gacagccatt ttaccatccg
    48661 attttagata gtaatttcct tgccatgtac tgtaagcata agaaccatct gatttcaagt
    48721 aataccaagc ttgataggtg gcatcataaa cccattcacc ttgtgccatt ttaccgtttg
    48781 atttaaggta ataagctcct tgccatgcat tgcgagcata agaaccatct gatttcaagt
    48841 aataccatgc ttggtaagaa gaatcataaa cccactcacc ttgtgccatt ttaccgtttg
    48901 atttaaggta ataagctcct tgccatgcat ttttcactag atttccattt ccatcaaaat
    48961 agtaccaaga accgtcctgc ttaacccaac cacttgctgt ggatgaagtt gtatcagttt
    49021 gagttgtagc cgcttgtttt gctttaaaag tacccttagg agcatttttc aattcgcaag
    49081 ccacaccatc atgatcgcgg tctaacttgg cagaataacc aggttctccc tcatgaagat
    49141 ccgaatatcc attagcccaa gcttccttac aactcgaaaa atgaatgttt tcctctgcta
    49201 acacaggttg tgaaaacaag gctaaaattg gcaacgtcac cagactcatt tttaaaaata
    49261 gacgtttatt catttctttc tcccataatt atgatatcga tttcaatatt attttatcaa
    49321 acttatttca gcaattcaag gaaacttctg gtcttttcta caaactcctt tggttttgcc
    49381 ttattcaaga catgagggcc atctgagata atctgaaatt gggattctga tattagttta
    49441 tgaagacttc tcatagaact aagattcggt ttatctttga taccacaaat tagtaaggtt
    49501 ggataagggc aagttcctgc tatatccgtt aaatcaagtg tcttcaactc ctcagaaact
    49561 ccgaccataa gagccttgtc tgctccctgt ttttcaaata ctcttttggg aagtagttta
    49621 aaaatcagca actgaagata aaataggata ttccctgcta atttaagcgg gcatcctgac
    49681 agaatcaaag ctcgaagatt tggtaaatcg taactggaaa gttctagtgc cagggcagca
    49741 cctaaggaca atccaatcaa aacaaaaggt tctgtctctt gagctaggta ctgataaact
    49801 cgctccttag cttgttgata gttactaact ccagaaggaa ataactcgat agcctcagaa
    49861 ggataatctg tcagtagatt ccgaacttct ttccaagact ctgctgactg ccctaaccca
    49921 tgcaaaaata tcagtttcat ctagttctcc tcaaggctta gttcatacaa gcctctcact
    49981 gcattacagc cgtaaatagc ttctgcttgg gctaaatctg ccaaggtcaa gactttctct
    50041 tctacctgtc ctgtttctag caaatactga cggtaaattc ctggcaagat tccaagtcgg
    50101 ataggcggtg tgtagagttt tccagcgatt ttcagaacca aatttcctat agaggtttca
    50161 agcagttctc ctgacttatt gtggtaaatc ttctcttgtt ctcctaggct caaatgcggt
    50221 cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag cagcttcctg aaggcagact
    50281 tgggcctgac aaaagcttgt actgagaggg gttaatactt gacgattgac ttctatctct
    50341 ccagatttgc taaggctgat tcgcaagcgg taatcttgat tagcttcaca atcctgacac
    50401 tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag gaaaggcaaa ataacgacta
    50461 gcttttctca gtctttccag atgtttatct tcaaacagca ggttcttctg gctgatttcc
    50521 cctgtcgtaa tcagttggaa gcgagcttgt ttacgataaa gaactgctgc cttttgatga
    50581 acctctcggt attcagattc ccatgtgcta tcccaagtaa tccctccgcc aactccataa
    50641 atagcttgac ctttgtgaag ttgaatggta cgaatggcca cattaaaaat ccgtcgtcca
    50701 tttggaagca agagaccaat cgttccacag tagactccac gcggttgagg ctccaagtcc
    50761 ttgataatct ccattgtcgc aattttcggt gcacccgtta tggaaccaca aggaaagagt
    50821 gagcggaaga ttttaacaag gtccacatcc tctcgcaact gactcttgat ggtcgaagtc
    50881 atctgccaaa cagttgaata ctgctctacc tggcacagac gctccacgtg ctcgctccca
    50941 acttcagaaa tacggttcat atcattgcgc aagagatcca caatcatcat attttcagag
    51001 cgatttttgg gatcctgttc caaccaactg gcctgttcaa gatcttcttg gtcagttacc
    51061 ccacgctgag tcgtcccctt cattggtcgt gttgtcaact cgcgatcatt ttgctcaaaa
    51121 aagagctctg ggctcatgga aatcactgcc atctcgtcat gttccacata ggcattgtag
    51181 cccgcttcct gctctaccac catacgattg tagatggcaa aaggattggc acttaacttt
    51241 tgcttgagtt ggacggtgta gttgacctga taggtgtctc cctgcctcaa gtgatggtgt
    51301 atctgggcaa tggccttttc atagttctct gcagacgtta cttcctgcca atttgagggc
    51361 aaatcaatat cctcataagt cagaggaata ggggaggtct ctaccctatc atgaacagta
    51421 aagtaaagca ggtactctcc cagtagggga tccttgtgaa ctgctaattt ttcctcaaaa
    51481 gcaggtgcag cctcgtagct gacatacccc accacataat aaccttgctc ttggtagctt
    51541 tccacttgtg ccagcaaatc tgccacttct tctacatttc tcgttttcaa ctctttaata
    51601 ggctggataa aggtatatct ctcccccaaa gtcctaaaat caatcactgt ttttctatgc
    51661 ataccttaag tatagcataa aataagaaaa ccctcatccg caaagcagat gagagatttc
    51721 aattatttaa agattgaagt tttaaagcta tttgtttgtt gaagaagttt cttataaact
    51781 ttttctttta cttgcacaag tttaccatta actttattag taaccatatc ttcttcaaga
    51841 gctttggcaa ataatgattt taattcatca tagttatgaa tggtctcacc atcaatagta
    51901 aaaggagtaa aaccagcgtt ggctttttct aacaattctt tataatattc tttcttaaaa
    51961 tcagcaaacg attggaatct gccgtcagat attttttgta taatatattg atctccaaat
    52021 tgtttccctt ctttattagc ttgagatttt aatttatctg aagcatatcc taagaatcct
    52081 ttatcatagc cataatatcc ccagagtcta aatgcattat tcttaaatgt aacagcaccg
    52141 ggtgcaccct cacttgtgtt acctgcatag atactattca tcattttaat tcctacatag
    52201 gcaatacctg gatcaaatac ttctggctta tatatattat tattcatcat acgattagtc
    52261 atcagattat tatcaactaa gtcattaaca ctgtttaatg ttattccttt ccaatcatca
    52321 gaactcatat ttcgaacctt gtcatattga tcttttgacc ctacagtgcg ttcaatagga
    52381 tcaactttct taaaccacag ttgatttaat ttatcatcat gtttactaat gactgcatca
    52441 ccttcaacat aatcaagaag agacaaggta tctatataac ctttcatata attatcaatg
    52501 tcttctcttg ttttaagagt cttcggatcg gtaatatacc actgatttcc atcatttgga
    52561 cgatagaaag tcatattaat tcccaaagca ccgtattcat caaaccatgt acttggtact
    52621 ggtgtttgta acattccttg tgcataggct tctgcatgag tccctgagcg acgtccatat
    52681 cctcctaaat agattgcacg atcattaaca tgagtagttt catgtgtata aacagagatt
    52741 ccaaactcat caatcatact taatgcaata taatttactt ctgttcgcgt atccaaagga
    52801 ttatcccaaa taactgcata agcacctgtt ccattgttac cataatactt accaataggt
    52861 ccaaacaact ctctcaatgg ggcatagtct tctttattat tcctcttacc atacttatca
    52921 ggccatccac caggtgcttg ataaccttcc caaagaggag ttactgtatt tttgactagc
    52981 atattcttaa ccttatctaa agataatcta taccaaaaat caaagtaatt tcgataactg
    53041 tccgctgctt tttcgatctg attttttatt ccatcgaagg agctatgccc taacttttct
    53101 gctgttccaa cagccattgc actataattc gagattaaat acacatgtga tttatttaga
    53161 tttaataatg ggagtatcat cttccgatga gtagcagatt gtaaattatc ccaaacttta
    53221 tatttcgccg ctttaatttc atcgacttcc gaagcacgct ccgctatata gacattccct
    53281 tctgtagctt tcttaaacca atcataaata tttacatctg cagtaaatag tcgacgatta
    53341 taatttaaaa agtttaccaa attttctgat aaggttgtct tagaaataat ctcgctgaaa
    53401 gcatcatatg tccgatgacc ttttatatta tcttctcttg aaccgatttc aattaatcta
    53461 tctaatacac ttacattttt accatagaaa tctggtttga ataacattaa ttctttaatg
    53521 ttaacatcac cgaatttaac accgtagtaa cggtttaagt atgttaaacc taataatagg
    53581 gcagctttat ttttctcaac tttatcaaga atcatttgtt gagctgcaga tgaattattc
    53641 agttgatgat cttcattttc aactaattta gttactaata tgtttaaatt agcttttaca
    53701 tggtcaaaac tttcttctaa ataaaggtct ttaattgcat ttactctatt agaccctgtt
    53761 ctgccaagtt tttggtaaat tggattagat tgaagctcaa tagggcttaa gatatttacg
    53821 ataccgttaa ttaaagcact atgatctttt tgaacgatat taggtgtata tttaatacct
    53881 aagtcagtta tagtgtattc tctaacatta cttagacctt catcactaga agataggttg
    53941 aagtagtctt ttgttccatc agcataatga acgataattt tgtttgcatc acctaaatca
    54001 gttacaaagt tattattgtt cataggagta accgatagaa tctctttagt atttaacttg
    54061 ttgttcttat ctagtttatt agcttgatta acgataaaat ctttgttata gaatggttgt
    54121 agtttttcaa tattcttata agcaagttta tagtctgcat tataatcttg aatagactcg
    54181 taagctgctt cacgactgct aacattattc aatttgttca attcataagg ttcacttacg
    54241 aatttagcag cagtaatatt gaaactagca acttttgcat cagcctcaga tttagataag
    54301 tgttttaatt tatttttgtt tttattatct ttaccagttc catcttcaga agagctatat
    54361 ccaataactc caaataaatt agacacaaaa ggatttgcat ctccatcatt aacatcgttt
    54421 gaaccgaata tttcctgacc tttaataact ttcgcatatg ttacattatc ttgaaccgct
    54481 ccatatggcc aagttttaga ggttattcca ccaacatatt tagtattttt aacatcaaga
    54541 ataccttttg ctacagagtt tgtaagtttt ccttttgtcc ctgatagcca gctatgagct
    54601 ttatattgaa cgaaaggaac aagcatactt gcatttgcgt tatttgctgt aatagtagca
    54661 tcaacgtagg ctctattaac aaaccccata tagttagaac cggcaatacc tccaactgtt
    54721 gaattattac cagcagaatt tatactaccg ataaatgcca cattttctaa agtagcgtct
    54781 tcttttatgt tatttacgaa cccagcaaca ttatttctag ctgttatggt tccgattgct
    54841 ttgatatttt ctatacgtgt cgttccactg atttcatttg ctattgcagc gatattatct
    54901 tgattagata aatcaatatc aatattttca aaatttatat ttttaacagt tccagcctta
    54961 atcttatcga ataaaggatg ttccaaatta tggatagcat agcgtttatc accatcactc
    55021 aatagtttac cagtaaactc tgaagtaata taagatttcc ctttaggaac aacgttacga
    55081 gcgctcatgc tttgacccag tttaaattca ccggcaggat ttgtctgaat ggcttggatc
    55141 aattcttcaa agtcgtagaa aataccagcc tgactagctt tgggtttttc aatatagtag
    55201 gtataagttt cttcaaagcg attatcgaca ttacgttgga ccaagttatc cgctactgct
    55261 attaccttgt agacttgttt tccatcaatt gttgactctt caattttttg aaccgctagt
    55321 agattggtct tatggtcatt agaggtaact tttaaataat aatttgacaa atcagttggc
    55381 actgaagtca atcgagtttc atcagtttca acttggtttt catatttgat taaatccgtt
    55441 cttataatat cttttatttc aacttttttg agatcaattc ttagcggttc ttctttcaga
    55501 acttcttcct catccccctc accacggtca taaaccatct ttgtttcaag tttataatcc
    55561 ttgtagtact gcaaatctgt cagggtagtt gtcaagtctt ctggtgaaac attcaaggtt
    55621 ttgacaatct catcaccttt tttcagagtt agggtaatag atttaatggc tgccttactt
    55681 ggattttcta aactatactt aacatctgaa gtacgcttca aatccttaga ttcaatttct
    55741 gtgatggtca acactggttt ttcaaagctc ttggtaccac gtttcaaaat tttgtcttga
    55801 ggttcctcaa ggatttcctc tgtaactttt ggagcgtctt ctgttttaac tcccttaatg
    55861 gtattaaagg tcttggtgat ttttttctgg ccttcttttc cttcttgagc tacaacttct
    55921 aagccttttt tcagttggtc atcttcttta acaacttcct taaatggaat cttttcaaga
    55981 ctttcttcta taagagttcc ttcaattggt tttgtaccac ggattacctg ttgatttaca
    56041 ggctccttgg tcacttccgt actggttgaa aggactttgt ctgtttccac accttccact
    56101 gtttcgtaag ttgttttcgt aacttgaact cctttagaac caggattttc aactacttcg
    56161 tcacccacat attttgtgtc atccggaact acgtctgttg tgaaatctaa ttcactttca
    56221 atagacttct caactgtacc tgttgttact ttatattctg gatgtacttc ttgtactggt
    56281 gcttgacctt ctttgccttt ttcttgcgta cctttagctg ttttagtctc ctcttttggt
    56341 tctacagttt cttcaggaac ttctggttgc ttttctggct caactggtgc cgttggtgcc
    56401 ttttcgtctt ctcttggcgc gactggttct actgatggtt caacttttga ttcctcagct
    56461 ggtttgtctg atggttgact ttccgatttg actggtgctt gttcatctgt ttttgaatca
    56521 actgctccac ctacttcttc aactggagct gattctactg aatcttcttt cccctcttct
    56581 actttaggaa gggtgtcgtc agtaggtttt acctccgatt ttggttcttc ctttggactt
    56641 tcttctgttc taggtgcttc ttcttttgga gcttcctctg tctctactac ttggttttct
    56701 gtcctagctt gctcctgatt tgttgttgat tgaggagtct caacttcgac tacagtcacc
    56761 tctccaggtt ttgctgaggt ttcttctaaa acagtgtcca agccaagcgt tttgaggatg
    56821 tcacctgata gataaccaac atagcgatag ccatccattt caacaacacc ctctcgacta
    56881 gccagcgcta gggtcgcaac tgggtctaca gcccctgcac taggaagaac taccaatccc
    56941 atagctccaa ctagaaagac gctagcaatt ttctttctct tgtagattaa aagcaagctc
    57001 ccaacagtca gcaaaccaaa agctgtcaaa acagatgctt ctgtccctgt ttgaggcaac
    57061 tgatcttttt gatacaccaa accatataca acttcattcc tgtcaggctt tcctgtctga
    57121 attaaatctt tagcttcttg tgaaataatc tctttattta catagtgata ggtggctgcg
    57181 tccactacag aaggagccat caaaaggctt ccaagaaata cagagcctac aactccctta
    57241 atcttacgaa ttgaaaaacg gtctttttta aacactttta tctcctttat tcattctcaa
    57301 gacttcctaa tagcatcttg cggatagtgc gcacgcgcac ctccgattaa ttttggacga
    57361 ctagccagtg ccgttacatg ggcatgacca atctctctca aaatagggcg aatcggaacc
    57421 tgaacatgct tgacatgcat gccaattgca gtgtctccga tatccaatcc agcatgagcc
    57481 ttgataaatt caacctcaac tggatcctgc ataaacttaa aggctgccaa ctgccccgaa
    57541 cctcctgcat gaagagtagg atggacactg acaatttcca gatcaaactg ctctgccacc
    57601 tgacgttcaa caacgagagc ccgattgaca tgctcacaac cttgaactgc taaatggata
    57661 cctctactac ctagaatacc caagatagtc tccactatca gctcaccaat ctcttgactg
    57721 gattctttcc caatctgacc acctagcacc tcactagaag atagacctaa aacaaaaagg
    57781 gccccctgct tcaaattggt cttttctaaa acatcttcca ctacctgacg tgtttctctt
    57841 tgaatctgtg tctcgttcat ctctgttacc tctgttgtca ctcttctatc ataccgtttt
    57901 ttcttgtttt tagcaagata gacaacctag aaagtttgcc caattacgca taaaactccc
    57961 agaattgact gggagttagc tagtttctat tctatttata tatatttcaa ctttcgtccc
    58021 tttttggggt ctagaatcaa tcttcatctg gtaattggct tcaaaatgaa gtttgagccg
    58081 ttgatcgaca ttttgaagac caactccccc acgtttgagt tgactttgac tactatcacc
    58141 agcatcttgg aagccaacgc catcatcctc aatacggatg accaatcccg aatcctgttt
    58201 ctggacagaa agtttaatat ggccctgacc ttccttttcc ttaatgccat ggtaaagagc
    58261 attttctaca aggggttgta ggaccagctt gggtaagact aaattatcaa aggcaacatt
    58321 ttcattaatt tcatattcca gcttatctcc atagcgttgt ttctggataa agagatactg
    58381 gcggacatga ttgatttcgt cagagagaca aatcaagtcc ttgccttgat tgagcgccaa
    58441 gcggaaatag gttgccaagg acttggtcac ctgcaccact cgctgactat catgaaattc
    58501 agccatccag atgatggtgt ccaaagtgtt atagaggaaa tgtggattaa tctggctcga
    58561 aagggcttga agttggtact gacgggtcgt ttcttcctgg ctacgaatag ctaccatcaa
    58621 ctgatcaatc tgatccaaca tggcattaaa ttggcgagtt acttctctca gttcataggc
    58681 accaacttcc ttggcacgaa gattttgagc accagaagca atttccaaca tggtttctct
    58741 caaatccttc aaaggagcaa tccagcgttt aagactgaac cacactaagc agagacaaac
    58801 aagaagagat gtgacactgg ccccaagcaa ggtccacaag agctgactcc gaacctggtc
    58861 taacttttcc aatgatgaca cgccaagtac cgtccaatca gttcctgcaa tcttctcttg
    58921 actgacgtag gatttgtgac caggagtata accctgacct gtctcgatgt agggtttcat
    58981 agcctccatt ttgctagacg aactataaac tgtgtgttga ggatggtaga caaattcatg
    59041 gttttcattg ataatgaagg caaagccctg ctgccccaac tggagttgat tgagataggc
    59101 ttccagagtt tcataagaaa tatccaaacg aagcacacca agattggctc cctttgcatc
    59161 aacaagttct tgagtgacag aaatgaccca ctgactatct gatttacgag ctggagtcaa
    59221 aacaggcata gctccctgat gaatggcctt ttggtaccaa tcctcagcca tcatatcaga
    59281 ggaagttttc atctgcacac tgtcatctgt agaaatgacc tgaccagatt tggtcaccag
    59341 cacaacagtt ttcaagtcct tatctgactt caagatggtc aaaaacaaat ctcggattcc
    59401 ctcgaccttg tcttgactgg gattctcagc ataggccaga acatccgtct gctgggtcaa
    59461 accagtcgag gtggtttcta gttttttgat ataagactga ataaagtggc tagtctggct
    59521 gatggtcgtt tggctgttgc cctcaatggt ggcctcaatg gctgaagaac ttgattgata
    59581 gtagaaagtt ccaaccagag ctaggagaat gagaaagacc agaaagatgg aaataaccat
    59641 tctaactaaa agagaagaac gcttcatcgg tcttctccct tcttaaactg acgaggtgtt
    59701 acacctgcaa tctgcttaaa acgttgggta aaatagttca tatcttcaaa accaaccttc
    59761 tctgcgatct cataaatctt caaatctgta gttaaaagca agagcttggc ttgtttaaca
    59821 cgttctctca ccagataatc ctgaaaaggc aagcccaact ctttcttaat caaggaactc
    59881 agataggtcg gactaaaacc taagtcactg gctaaagact ttaaactaaa ttggctatca
    59941 gccagatgag actggatttt ctgggccatg tttccttcaa acctattagt caataaatct
    60001 tgtaactgct cttctttctc ttccttgtct agtttttgtt tgattttccc caacatttcc
    60061 tcaatatcct gacgagaaaa gggtttgagt aggtagtcgt ccacacctag tttgacagca
    60121 gacaaggcat aatcaaaatc atcgtaacct gttaaaaaga ccaaatgaac ctgaggatag
    60181 gtttctcgta ccagactggc caactggatg ccatttagat gaggcatgtt gatatcggtt
    60241 aaaatgatat ctggcacctg cttttggatc aattcccaag cctgccttcc attttcagcc
    60301 tgaccgatga tttccatatc gtaggctgct acattgacca gtttagtcaa accttgtctt
    60361 accagatatt catcttctac gattaagatt gtgtaggtca tgatctgctc ctttaccact
    60421 tactagtatc agtatagcaa aattctcctc taactgctta ggaaagacct cttatactca
    60481 ataaaaatca aaaagtaaac taggaagata gccacaggtt tctcaaagta ccgctttgag
    60541 gttgtagata aaactgacgg agtcagtaac cctacatacg gtaaggcgac gctgacgtgg
    60601 tttgaagaga ttttcgaaga gtattaatca acataatcta gtaaataagc gtagcctttt
    60661 tcttccattt ggtctttggg aataaagcgg atagagaggc tattgataca gtaacgtaag
    60721 ccgcccttgt cctgtggacc atccgtaaag acatgcccaa ggtgagaatc tcctactcgg
    60781 ctccgcactt ccatacgcgt catattgtag gacttatctt ccttgtaggt gacaacatct
    60841 ggactgatgg gttgggtaaa actaggccag ccacaaccag actcaaattt gtcttttgat
    60901 gaaaagagag gttccccagt tgctatatcc acatagatac cggattcaaa tttatcccag
    60961 taacggtttg agaaagctcg ttctgtttga ttttcctggg taactgcata ctcctcaggt
    61021 gacagggtct ttttcaattc ctcatcactt ggttttggat atttgctggc atcaatgaca
    61081 ggataggccg cctgattaac attgatatgg cagtagccat ttggattttt cttgagatag
    61141 tcttgatggt aatcctcagc caccacaaaa ttcttcaagt tttccttttc aactgctaga
    61201 ggttgatcgt atttcttagc cacctcatca aagacttggt taatcacttc caaatccttg
    61261 tcatctgtgt aataaacacc agtacggtac tgggtcccca catcatttcc ttgtttattt
    61321 ttgctggttg gattgataat gcggaaatag tgaagcagga tttccttgag agaaatttgc
    61381 ttggcatcat aggtgacatg gacggtttct gcatgacctg tttggttaat caattcgtac
    61441 ttggttgttt ctcctctacc atttgcatag cctgaaacgg catccgtcac cccgggaacg
    61501 cgtgagaaat attcctccac tccccagaaa caacctccag ctagataaat ttcgtgcaag
    61561 tctgcgtctt tactaatttc tgtttttttc actgcttttc ctccttggct aactgccgcc
    61621 ttttcaattt gcgaggcatc tgtctgccct gcatttcgta tcaatagaac atagaaaccg
    61681 gttatggcta gaaaaaatac tcctagcaac aagaagattt ttaacttatc attcataaga
    61741 cacctcctag gctaattcct tcaaagtttg caaaattgca tctttttcca tgaatcctgg
    61801 atgtgttttg accaacttgc cttctttgtc tataaaggct tgggttgggt aagaacggac
    61861 accataagtt tccaaaagtt tgcctgatgg gtcaactagg actgggagat ttttataatc
    61921 caatccctta taccaattct taaagtccgc ttcagattgc tctcccttat gtcctggtga
    61981 cactactgtc aagaccacat agtcatcacc agcttcttta gcaatctcat ccgtatctgg
    62041 aagactagcc agacagatgg aacaccaaga agcccagaat ttgagataga ctttcttgcc
    62101 cttgtaatca gataaacggt aggtcttgcc atctactccc atcaattcaa aatcagccac
    62161 ctctttccct ttagctgcgc ttgttttact agctgtctgc tccgtcttca tttcatcttt
    62221 cgtttggtgt tcactagtca cggacttgcc tgaacaagcc gtcaaacaaa ggagcgaacc
    62281 tgctccaaga acacatgttt gccatttttt catattgata ttcctttcca ttttattcaa
    62341 ataattgact taaaattgaa gcatttccaa acagaaccaa gagtcccatc acaataatga
    62401 gaaaaccacc cacttttttg aggattccga gatagggatg aagttttcgg aaatgtttca
    62461 aaacataact agaggtcaga gctagaagca agaatggtag cgccaagccc agcgtataca
    62521 ccaacatgag accagctccc tgccaagctc ctgaaccacc tgaagccgcc aaggccaaaa
    62581 cagaccccag aaccggcccc acgcaaggcg tccaagcaaa actaaaggtc aagcccaata
    62641 aaaatgcctg actatagccc ttaccatttt gcccctgtcc ttgcagttgt agcctctttt
    62701 ccttataaag ccccttaaag tgtagaatct ccatttggtg caaaccaaga aggataataa
    62761 ttgccccagt aagatattgg aaccaagaag cataaagcaa atcgcctaaa aaaccagctc
    62821 catagcccaa caaaataaat ataaaggaaa ttcctgctat aaaggccaga gttcgtaata
    62881 aactagtaac tgagattgaa aatttgccgc tagaagcctg agcaccatcc ttatcatcta
    62941 gtaacactcc tgtatagacc ggtaacaaag gtaagataca aggagaaaag aaggatagaa
    63001 tccctgccaa aaagacactt agaaaaaaga aaatatgacc cataaagttc ctcctatcat
    63061 tttattgata gatttattat actccttcca ttttcgaaaa aacagggaca atgatagggg
    63121 aaaataggaa tttaatcaga tgatttagaa atcttggaca aaaactatac aaaaaactgt
    63181 caaagcacaa aagcgcatag tatcaaggtt ctataaagtt ttgatactat gcgcttttgt
    63241 aatggataaa tagttagtct tttttaaaga ccggatcttt caaactctgc atactggcat
    63301 tgataaccgc gcctaggata acaattttag caatcaagat aaaccaaaac atcataacaa
    63361 caagaagaac ggaacctaaa attcggacat ccaccaaatg atggacatag taattgagat
    63421 aactagagaa cagagttagt aaacctaaaa tcactaagag aacaaaggca ctgcctggta
    63481 gggtatagct aattttcctg ttagatagat tgggaagaaa ataataaagc atgaccaaga
    63541 tagcaaagag gagggcgtaa atcagaggac ctgccaaccc ttgtaaagcc tgatagataa
    63601 tgccatcttt tgtccaataa tgagcaagta aagccaaaat catctgacca aataagatca
    63661 aaaacaaggc aaacgcaaag aggagctgca agccaaaact gactaggaga cttagcatct
    63721 gatgggaaat aagtccacga ctcttttcga cgccataagc cttgttaaaa gctttttgca
    63781 agaaattcat agattttgaa aaactccata acgccgataa aacagaaaaa ctcaataaac
    63841 ctgttgaagg ttgcgtcaaa acttctctgg ctattttttc cacaccttca tagaggcttg
    63901 ggggcagaac gtctttcata aagcacagaa attctcccac aggaatctga aaatagggga
    63961 ggatattgac caccaccaaa agcaggggga aaatcgaaat caaccaatag taggctactg
    64021 cgacactggt caactcacta tctgatgctt gataataatg caaaaaagct tttaataaag
    64081 gcttgtctat cagctctttc caccactttt tcatgtcata ctccttcatt tataatctta
    64141 tactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc aaagccctgc
    64201 tttgaggttg tagatgaaac tgacgaagtc agtcacatat ataatccaag gcgacgctga
    64261 cgtggtttga agagattttc gaagagtatt aactaatttc ttcttaccaa ttccaccata
    64321 tcatacggca gggtattggc agcttccttc aaggaatagt tctctaagtt atttacattt
    64381 tgtcgtaatt tcttggcata cttagtcgta atcaatcgtt tttcttcgta ttcgaaaatc
    64441 aacttgcgct ccagataata gcctctcagc atttcatcga tattgttggg tttgacacga
    64501 ttgataaccc gttcgacaaa ggcaccactg ctgataatag ctgtttctcg aagacgagac
    64561 tcctgcataa aactaatcaa agagcgtctg tagactccct tcaggttttc caaactttca
    64621 ataatcatct ctgtattggc aagatagagc tctgcaattt ggtcataatc aagagcacgg
    64681 agacggcttt gctccttgtc cttccagcta cggaaggtct ttccaagagt aaaaacttca
    64741 tgaaggagaa aacgtaaaat cctcaaggaa acaagaaaat aataggtcag tcttgaggca
    64801 agtttacgat tgattccttg ttctatattt ttcagataac gttggtaaac tcggtaagca
    64861 cgattgctaa tgttcccctc ttcataggcc tgttccaaac catcactttc aatactaaga
    64921 atcaagagtt tcaaagcagc ccaatcttct tgatcatcct ggttttcttg gcttaaaatg
    64981 agattttcaa tacgtccatg ataattgtca atagccgcat agaggggaag tttatttctg
    65041 gtgtcttcca actctttttc caactctagc gttacttcat tcaaaatggc gatatgcatg
    65101 agataatcct tgctttcttc ctcttcatca gaaagatgag gcaagaccaa gagacctgtt
    65161 aaaaagctga caagcgtcac acctgcaaca aggaaaagca aaagaggata ctcctgttct
    65221 agattacttg gtatcaagag aatcgtagca atcgacaccg ttcccttaac acctgaaaag
    65281 gtcaagagaa acatgtcctt catatactta tttagctttt tcttgaggcg tcgggttcta
    65341 taggcataat agccatagat cataataaaa cgaatgacaa agaggacaaa ggtaagggcg
    65401 atgagagata gcaataaaag tagaggatta tagattggat tggtcaagat aggttctgct
    65461 atcatttcca actccatccc taaaatcaca aagacagaac cgttgagcat aaaggtcact
    65521 gtatgccaga ccgtctcggt caccgtatcc acttgggctt cgaggagcgt gattttcttg
    65581 aagcgacttg cctttaaaat tccagcaact acgacggcaa taatacctga aacatgaact
    65641 tcttctgcca gaaagaaggt cactagaggc aaactcaatt ctaataaaag ttcactggca
    65701 atatccgttg cgcgcacact tagcaagaag gtatggagga agcggttggt catggccgtt
    65761 aaaaatccaa ttaaaaaacc gcctaggatt gaaaagatga gcgaactgct agcttgcccc
    65821 agagaaaaag ctccagttgt ccaagctgtc aaagctacct gaaaagccac caaaccagaa
    65881 gcatcattca agagtccttc gcccttaaga atattggaca cgcgcttagg aaagctaaaa
    65941 cgctccgaaa gagaggcaaa ggccaccaag tccgtaggac caagggctgc cccaacagcc
    66001 aagcaagctg ccaagggaag gctgaaccaa agaagatggg ccaagccacc caaactcaag
    66061 gtcgagataa aaatcactgg aaatatgaga taaacaatga ttcgccagtg ttttaaaata
    66121 gccgtaacat ctgcttcttc agcctctcgg aaaagcaagg gtccgataac cagtgccaaa
    66181 aacaactccg tattaaggtg aaagtcagta ttgggtaaaa agagaccaat cacaattccc
    66241 aaaagaatct gcaccaaagg gagaggcaaa aagggcagga gcttattggt tgtacttgag
    66301 acaatcaaaa ccagtaaaaa taggatgagg taaatcagta attccacgca cgtcctcctt
    66361 aatctttttt acaacaggat tcaaatatct ccttctgctc tttgattttt tggtcaatct
    66421 tggaacagtc tttgtgctca atttttctct ggcaccgttc catttcaaga gcaactaatt
    66481 ttttcttgat tttaagcatt tttttgctca tatgcgcttg gtctagcacg cccaccgatc
    66541 gttcgtggtg ggttgattca acaaaattct ggcgcatggc atccagcttt tcgtgtaggt
    66601 attgtttatc catgtctgta tctctctaat ttttcaatca tcactaaaaa cggcgggttg
    66661 ttgacttggt ttaaagttcg gtaaatggca gctgtgtact cttgttggtt caactggatc
    66721 acaaaatcca agacagcatc tctctcgaga tcgcctcctt catgaccata gtaaatcata
    66781 atagcaattc gtccaccttt gacaagtaag ccacatagct tttctaatgc ctcaatcgtt
    66841 gtctgcggtc gggtgatgac agacttatca gctgacggca aatagcccag attaaaaatc
    66901 cctgccttag cttttatcac aaactggtcc agtgtctcat ggccttgcaa gattaactgg
    66961 gcatttgtca agtcagcctg atgcaaacgc tcttgggtct tttccaaggc ttgcttctga
    67021 atatcaaagg catagacttg cttggctagc ttggctaaaa aaagcgtgtc atgaccattt
    67081 cccatagtcg catccactac gacatcctct tttgtcacga cctcagccaa aaaatcatgt
    67141 gccatctcaa gtggtctttt cattttcaaa ctcctgtttt acagccttgc atccttgaac
    67201 acttccacga cgtcgcatct ccatctcaat gctgttgaga gcttcccatt tattgaggct
    67261 ccacataggc ccaagcagca tatccctagg cgcatctcct gtaattcgat ggatgacgat
    67321 atgtttggga ataatttcca gttggtcaca gatgaccctg acatattcgt cctgactcat
    67381 caattgtaaa cgcccctcat ggtaatctcg ttgcatacga gtatttgtca taagatggag
    67441 caaatgcagt ttaatccctt gaatatcgtt atccgtgaca caacggcgga cattttcaac
    67501 catcatctca tgggtttcac caggcaaacc attgatcaaa tgggaaacaa tctcaatttt
    67561 tggatacttt ctcaaacgct tgaccgtttc cacctacaat tcataagaat gcgcacggtt
    67621 aatcaggtca gaggttgctt cataagtagt ttgcaagccc aattcaaccg tcacatgcat
    67681 gcactccgat aactcagcca aatattcgat ggtttcgtct ggtaaacagt ctgggcgcgt
    67741 tccaatattg attcctacca cacctggctc attgatagcc tgttcataac gctctcgaat
    67801 aacttccacc ttttcatggg tgttggtaaa attttgaaaa taaaccagat acttctgaac
    67861 atctggccac ttacgatgaa taaagtcaat ttccttataa aattgctcac ggataggcgc
    67921 atctggtgcc acaatggcat ctccagaacc ggaaaccgta caaaaagtac agcctccatg
    67981 agccacagtt ccatcacgat tgggacagtc aaatcccgca tcaataggga ctttaaaagt
    68041 cttttctcca aagagttttc gataataatc attcaaggta ttataagatt ttataacttt
    68101 cattataaca aaaatcaccc acaatctcaa aagcctgact ttcctataaa ttcctctgtt
    68161 tctcgtttcc attagccttt ttttatgata caatatgggt atgattttaa tgaaattagc
    68221 atctatttta ttattgatac tgaccttagt cgtctgcatt atcctaacca aactttttag
    68281 attaaaaaaa ctaggacgaa actttgcgga tttggctttt ccagtcttgg tatttgagta
    68341 ttacttgatt acagctaaaa cctttaccca taatttcctc cctagactgg ggctagccct
    68401 ctcgttccta gccattattc tcgtcttttt cttccttttg aaaaaacgca gcttttacta
    68461 tcctaaattc atcaaattct tctggcgtgc aggattctta ttaaccctta tcatgtatat
    68521 agaaatgatt gttgaattgt tcttaatgaa atagtcgaat ccctaagcat tttctaggga
    68581 tttttgcttt ctctacaaaa tagtatagac aataacacta tacaatttta tacaaagaaa
    68641 agagtctggg acaatagtct cttatatcca aaaaggcaac ggatttgccg ttgctttttt
    68701 gcatggttac gatagtcttg gtaaaataga attgcttaat aaaccattta gaaaggctat
    68761 cccatgcata ttcactataa cacaaatcaa acaactttac cactagaaat cagttccttc
    68821 ttaccacaag accatctcgt ctttactatt gaaaaagtgg tgaatacctt ggaggaacgt
    68881 cacttctacg ccttctatca tgcctttggt cgcccgtctt atcaccctaa aatgcttgta
    68941 tctactcttc tatttgccta ttcacaaggg attttctctg gtcgaaaaat tgaaaaatgg
    69001 aagagttagt gaccttagat tgtttgttta ttgacggaac taagattgaa gccaatgcca
    69061 acaagtatag ttttgtgtgg aagaaaacga cagagaaatt ctccgccaag cttcaagaac
    69121 agatacaagt ctattttcaa gaagaaatca ctccccttct gattaaatat gccatgtttg
    69181 ataagaaaca aaagagaggg tataaacagt cagctaaaaa cttagcgaat tggcactata
    69241 atgacaagga ggatagctac atacatcctg atggctggtg ctatcgtttt caccatatca
    69301 agtaccagaa aacacagaca gactttcaac aggaaatcaa ggtttactac gctgatgaac
    69361 ctgaatcagc ccctcaaaag ggactgtata tgaacgaacg ctatcaaaac ttgaaagcta
    69421 aagaatgtca ggcgctttta tctccccaag atagacagat tttcgctcaa cgcaagattg
    69481 atgtggaacc tgtctttggg cagataaagg cttgtttggg ttacaagaga tgtaatctga
    69541 gagggaagcg tcaagtgaga attgacatgg gattggtact tatggccaat aacctcctaa
    69601 aacatagtga aatgaaataa gaacaggaca aatcgataag gacagtcaaa tcgatttcta
    69661 acaatgtttt agaagtagaa gtgtactact ctagtttcaa tctactatac aataagagaa
    69721 cgactcaaaa ttaaaaagct agagttccgc aattggaaat atctagcttt tttgtggttg
    69781 agaactattt tgttccagac tctttatctt ctatttagga caagagtttt tctttggtct
    69841 ttaatgataa agaaggtatc aaaatttcta gtcttctttt ttacctttag taactactaa
    69901 tcctgcactc aaacctagaa gagctaaacc tgctgctact gctgcttggc ttgccgcact
    69961 acctgtattt ggtaactggg ctttattagt ttgactagct tcacttgaat caattggttt
    70021 tgtatctgct ttttctgaca cttgtggttt tttagcttct tgagctactg gtttggttcc
    70081 aaccaagacg atgcggtctg tcggagcttc taccacttca cggagttttt cttccttact
    70141 tccatcagga ttaatcgctg taaagatacg ttctttacca gtttttcctt cttgttctac
    70201 acgagtttca cctagataca gtgttgaatc ttttttctca actgtcttgt aggccaaatc
    70261 tttttcaaca aattcgagtt ttggaagatc ttcttgtaca gcagcaactg tcttctcaga
    70321 aactggtttt tccttagtca agtggatacg gtattccttg acttgttttc cactttctga
    70381 aacgaggcga acaagtactg gaaggctatc ttctccacta tctaccacag ttgaagctac
    70441 ttgattgttt tcttcaactg agacttttgg ccgttgacct ttataggtaa tttgatagtc
    70501 ttgacgattt tcagcgaaat cagcaagttc ttttccatct acaagaatct tcgattgcgt
    70561 gctttcttga ggcaattcac ttggtgcaag gaaggtcatc tcaatcatcg caacaccgct
    70621 cttatctgct ttacgctcca tacgccatct catagctttg gctttgacag ctttaaatgt
    70681 tacgttgatt tcatcaccag ctgcgatgtc tttatccgca cgataaggca cagcttccca
    70741 attttctgga ttgttgaatg gatggtctgc gtcgtaggct tggtagtttg aatagtaggt
    70801 tggcacttca aactctggac cgacatagcg ttctaaaacg agtttagttg gtgcatccgt
    70861 accactatct gcaaagaagt gaagtttggc ttgagcaaca gtccgttcta caatcttacc
    70921 attttcacgg aagatcacac ccgctgatac ttctggatta gaagatggtg ttggtgacca
    70981 gtttgtccaa cgacgatttt ctgaatgatc tccgtcattg agatagtcaa cgcggtcatg
    71041 agagtttttg tcaatatcat ttgttgctga agcaaaggcc tggttactgt tttcatcata
    71101 gttagggtta tctgaaagag cctcaccaag tttgtctgtc actcgtacag tgacctcagc
    71161 aacaaggtca ctaccaagga cacggcctcg aatagtaaat tgacctgctt ttgtcagatt
    71221 ttccgctgga acttcttccc attcaactgt caggtctttt gtttcgtagc tgtctttacc
    71281 tgtgaagtaa actggaacct tagtcggcaa ttcaagtgct tgacctactt gtagcaagcg
    71341 agcttgttta accgcagcaa ctggtttatg agaaagtaag ttcttatcct tagtgaagtg
    71401 cagacggtat tctcctaaga tatcgccatt ttcagctttc gcgatgacac gaactggctc
    71461 accttcacga acgcttggaa cgacggtagc gagaccattg ttgctaacac ttgctgtgac
    71521 tgccggaact tttccatcta cagactcaag gtagtagtct gtcaaatcag ggttgaagtt
    71581 tgctaagtct ttgccgtcaa cttggattct tgtttgtcct tgcttggctg ccgcaacttg
    71641 tttcgcaaag atttgtacct ctgtgataga cgttccacgc ttgttatctg ctttaaccat
    71701 gcgaatacga acagcatagg tttcaacttt atcaaagcta aagtggttca tttctccagc
    71761 cttgagttta gcaggggctt ttagattagt aactggtttc cagttggcag aatcattaaa
    71821 gacatggtcc tcattaccaa caaaactagg gtttttagga gctgttggga cagtcttgcc
    71881 aacataatac tcaatcacat aagacttcgg tgcaccaact ccatggtctt cgtggaatcc
    71941 gacacttaga ttatcaacgg agcgtttgct caagatacct gaatctccaa acagaacacc
    72001 gactgaagct tctggattac tacgattcca gtttgtccaa cgattggctg gttggttatt
    72061 gtaggaaatg agcttgtcat taacatttga aactgggtcg cttggatttg aatctgaagc
    72121 aaaggcaagt ggcaattctg aaccggtcca ttggtcagaa atgtttgcac cttgctcagt
    72181 ttgagcagat acgcgaacat gaagtttagt tgttaattga gtaccttcta agcgaccatt
    72241 aactgtaaag acaccttcct tagcgtattg ctctggacga atcgcatccc atgcaacctt
    72301 agctgatgaa acgtgaccat ttgaatcata tgtccgaacg ctttctggta attgtggtgc
    72361 ttctgcgatt ggagttgtca cactgacttc ttcaactgaa acgatacctt ctacagagac
    72421 ttttgcacgc gcttcaaggt caattccttc aactttacct agtacttcaa atatttgata
    72481 ggagtctagt ttttctttcg gaatagcttg ccaagtgact ttatgagttt tagggaaacc
    72541 tttgtcatac tcaactgtta ctgttgctgg aagacttggt tcctgatgca aatctgtgac
    72601 tacatttaca ggacggatag attgcgcaat cttcttctca gtattggctt ggatagtgag
    72661 ttcaacttgg cctttagctc cctcatattc agcgttcaga gtgactgctc ctggcttatg
    72721 caactcaagc attcctttac gaattgcgac ttccccttca ccacttgtag agaaggttac
    72781 tttatcagct ggtaatacag cttgcgttcc atcttgatag tgagctcgaa ccgacaattt
    72841 gacagtttgg tcttctttga gactgtcagc tttttccact tgcaagctca agtgagcaat
    72901 ttttggcgct tcttcaagga attgaattgc ataggtttga agagggccac catctttagg
    72961 ctgaataaag atgctcgcac gcatgccgtt tgctgcgctt gcttgaagaa ctgtcacatc
    73021 agcattttca gcacttgctg tgacttctgg caattgggca ccataagata gagtacgata
    73081 ttgcattggt tgtcgactag taagacctgt tactgcttca cctccaacag taacagttgg
    73141 cactacaggt gctgcaggat tgccttcttc taccacaagg gttgcatgaa ttggttgacc
    73201 ttctaaataa ccggtcgctt gaatacgaga acctggaatt gctaacttag ctttatcttc
    73261 ttcggcaatc tcccacttgt ccacttcata ctcttgtaca cttccatcag tcaaaacata
    73321 ggaaacagat ttgtctacag aattcaagtt agtatttgga gcaatacgtt tcacaactgg
    73381 tagctctgat ttaagagcaa tcacttctac acgagcttct acttctcgtc cgtcagccat
    73441 acctttcacc gttacaatac caggcttgct cacatctact aaagaccagg ttacaggacg
    73501 ttctgcacga ctaccatcac tgtatacaaa cggaacagtg gtaggcattt caggtgcctc
    73561 tccaataatg gtctgtactt ttggcacctc tgtccccaaa acagtctttt cttgtccttc
    73621 tttcttacca gtaaagacag tgacttggtt cgatttcaag agatcagagt gggcagtaag
    73681 ggtgaatttc cctgcttgtt cagttgattt gacaatggca acacctttac cattaaatgc
    73741 tttacgaatc caagaaccat ctgcttgcgc cttatagcgt tcacggctgg cttgttctcc
    73801 gttatctaca ccgaccagtt gaccttggcc atgcaattgg aagcgaacca gattattagc
    73861 agttggaacc acattcccct ggctgtcaac aatttcatag tagatgtaag tcaagtcttt
    73921 tccatctgct gcaatcgcat ggtcttcctt aataagacga actgccgctg gcttaccagc
    73981 agtcgtaatc ttatctcgag caatttcctt gccagattca tcacgagcaa ttgcttccaa
    74041 ggtacctggt tgataggcaa ctttccattc aagataaagt tcattagcat ttgcaccttc
    74101 ttggtaagtc cgcccatcgc tggtttgttt tttattgaaa gtcttaagac caagagattt
    74161 tccattcaag aacaattcta cactagaagc attcgaataa gcacgaactg gaatcttacc
    74221 ttctgagtca gctactttgg atgctaattc tttgttttcc cagttccagt gaggaagaag
    74281 gtgtaccatc ggtttcttct taacagaaac ccattggctt tggtagagat agaagtcatg
    74341 ttttggaatg ccggctgtat ctacgatacc aaagtaagag ctcttaacag gagtttgatt
    74401 ttggttgtgc catggtgtag gttcaccaat atagtccgta cctgtccaga taaactgtcc
    74461 agcatagcca gcgttgtcac ggtcaaaagt ccatgaagcg gttgctgttt tcccccaacc
    74521 cacacgatca tttccataat ctgactgttc ataattacgc tcaggtccat tgctatgttt
    74581 caattcacgt tcagggcgat agtaacttcc acgtgtacgg gttgctgatg atgtttctga
    74641 accgtaaatc aaccattttg gatgcttagc tctaagggct ttgtaattat cttcagaata
    74701 gttaaatcca acagcatcga gttcatcagc aattttctca tgccctccgc taccattacc
    74761 gaaacggaat ttatctgctc ccatggtaac atagcgagtc ttatcaacat ccttgataac
    74821 cttgaccaaa cgtttaacag ttgctaaaga gtgggcatca ccattagctt cacctatttc
    74881 attaccaatt gaccacatga agatagcagg gttgtttttg cctctttcga ccatggtacg
    74941 taggtcaaaa tcagaccatt tttcaccttt tcgagcttct gggtgagtgg catctttttc
    75001 aaagaaacgt ccatagtcat aaggtttctt gccaccatac caagtatcaa aagcctcttc
    75061 ctgaacgagt aaacctagtt ctgctgcgat ttgcaaggtt tgctcactag cagggttgtg
    75121 ggttgtacgg atggagttaa ctcccatctc cttcatttgt ttgagacggc gatattctgc
    75181 tttatagttt tcttctgctc caagcgcccc atggtcgtgg tgcaaggata ctccatggaa
    75241 tttaatacgt tcaccattca aagagaaacc ttcatttgga gtccagtgat agtaacggta
    75301 accaaacaaa tccttcttag catcaaccaa ttgaccgtca cggtaaacac gcgtaatcaa
    75361 ttcgtacaag gcaggtttgt catttaaaac ggtccagagt tttggtcttt caacttctaa
    75421 aatcgcatct aggcttgttg attcatgtgc ttttaaggta cgactcgctg tacgaactaa
    75481 gcctgttaca gcatgaccac ctcgttcaac gatttgatat tcggctacaa gttcatggtc
    75541 tttgtcgtcc gtattgacga ttttgctggt cacatgagtt tcaaccttgc catgttgttg
    75601 ttcttcaagt tttggtgtta aaatagttgt cccatttttc tcaacatgca ccttatctgt
    75661 cacttgtaaa gtcacatcac gatagatacc acttcctgaa taccaacggc tacttggctg
    75721 tttgttgact gcatggacag caatcacatt ctcacgacca tctttgtgaa ggtatttggt
    75781 gatatcgtat gagaactggt tataaccatt tggataatgc cccactaact gaccattgac
    75841 ataaacttga gaatccatgt agacgccatc aaaagtaagg cgaacatttt tcttgaggtc
    75901 tttttcatct agtttgaaag tcttgcgata ccaagcttcc ccaccgttga gctgtccacc
    75961 ttcattttgt gcaggagatt catgatcgaa atcgttaaag atactccagt catacggtaa
    76021 atctaatttt ttccacgtag atacgtctgc atcaggttta atggcttcct tagaatttgc
    76081 attgagttta aagtaccaat tttgattaaa atccactttc ctgtcttcaa tcatttgatt
    76141 cacttcttca tttgttacag ctttagcatc ttccttgagc ggtttttctt gacttgaagc
    76201 ttgtgattct atccttggag ctttttcttc cggtttagca gacacttttt cctcttttgg
    76261 agttacggct tcatcttctt tcttctcaga tgcaatagcc tcagttgaac taggttcact
    76321 ttgttctgtc ctttcaacta catttttagt ttccaaagct ttatcagcct tttcttctac
    76381 tatcattttt tcctctttag gtttctcagc agtatgagta ataagtgttt catccgcata
    76441 aactacagat tctccagcta tatttcctcc taatagaact gcacaagtcc caatcattac
    76501 tgagcaagct cccacagcaa acttacgaat gctataaact cttttccgat tccaatggcc
    76561 tttccccata aaaccctcct tatattatat ttagtgcagt tagctactac caaagcccaa
    76621 gtggtataca tggtatgaca acctagtttc aacaatttac actctgcgaa aatccaattc
    76681 aaacttcgtc agtgtcgcct tgccgtagat atgattactg acttcgtcag tttcatctac
    76741 aacctcaaaa ctgtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt
    76801 cattgagttt atattttata ggagcgcatt attttgcttt tgctgcgtac tcttcgttac
    76861 gtttgatcat ttgttttctg taccaagcaa agataccgat atagaataca aggaagacta
    76921 ctgcaccaag gattgctttg atatcaccag ttgtagtgtt accaattgtc caaccaagaa
    76981 gtttttcgat tggtccttca agagtagagt gagtaatcaa ttgagtttgg ctcacacctt
    77041 ctgggaaggc acctacacct ttagcaagtt ctgttgcaaa tggtgcaata agtgtacctg
    77101 aaagaaggaa gagtggcaac aagagtgttc cgaagataat catacggagc aatttaccac
    77161 gagttacaac caagagagct ggagtaacac ccatagcgat gatacctgca agtggcaaga
    77221 taccatttcc aacttttgaa agaagcactg cttcaatcaa catgattggt gcaagtacgt
    77281 tggcacaagc ccagatttca gcacgaccag cgatgaatgg ccagtcaaga ccgatattga
    77341 atttacgtcc ttgaagacgt ttagtagcaa cgtttgtaat accttgtgat agtggttcta
    77401 cggctgcgat gaaccatgaa ccgataagtg agaagagttc caaagataca ccggcagtca
    77461 aaccaagaga caaccatcct ttgataacaa gacgccattt atctgcatct gcaacacctg
    77521 caattggatg tggagttccc ataataccga taacgatacc aaggatgaaa ccgatgaaaa
    77581 atttagatcc ccagaaaccg attttcttgt tcaatttagc agcatcaaag tcatatttat
    77641 caaggcctgg gaagaatttt tcaaaaatct tatccaaaac catgataact gggttcatca
    77701 tgtagttcat gtgagttgat gtcattggtg atgaacttgg ggcgttaaga aggtcatcaa
    77761 atgtaggttt catcaagtca gagttgataa ttttcaacac accgacaagg acgatagctg
    77821 ctgtagcaat aaagagtgaa accccttgac tcacaccatt gttatcagca taccatttaa
    77881 tcaagagacc tgtgatagac aagtgccaga tatcaaagat atcgacatca agtgtatcgg
    77941 ttttcttcat agcaagcatc actacgttga caatcaacat gatgagcaag aagtatagtg
    78001 tccaagcaga accccaagtg attgttgcga gtggtgccca accaacgtcg gtaatactca
    78061 attggatacc agtgttttca acgaattttg caagtgatgc tgagaaagca ccatttagca
    78121 taccgatgat agcaccgata cctgtaagag cgatggcaag tttgatacca ccttcaagcg
    78181 ctttggagaa tttcactcca aaaagtaaag ccaatactgt caaaatgatt aacatgatga
    78241 caggtccacc catttctaaa atgggattga aaacctttcc gattaggtca aagattgcat
    78301 ccataacagt tcctcccttt tttatgttat atgaatgtta acaaattaga attagcttaa
    78361 tccgtgttct ttaatagctg cttcaatatt gtcaaatact ggagcgctca ttgctgggat
    78421 acggaataag attggcccag cttcgataac tgggatacct ggttcaaaac caaggtctgt
    78481 tgcagcgatt ggtgtaaaga tatcgtaacc tttcataagg tcttcgttta catctttcac
    78541 catgactgca tcacagtgaa catcataacc acggtttgaa agttcttctt ctagagcact
    78601 tttaatttgg tgacttgagt taacacctgc accgcaggca gcaagaattt taatcatttg
    78661 gatttcctcc gattttattt tttaatagac aagattaagc ggttgcttca gcaatgtaag
    78721 cataaagggc ttctggttca gaaatttttg ataggtcttc aagatgacca tttcctgtga
    78781 agaagtccat taactgagca agaatgttcg tttgacttga acttgagtta ttgatgataa
    78841 agaagagcaa ggatacttct acttccttat ctggcgcaat catattatgg aaagtcaccg
    78901 gtttctctaa tcgaacgacc acaacttttt cagccaaatt atgaacaata tctgtgtgag
    78961 gaatcgctac atttggcaag tcctttccta gaaattccat atctaaacca gttggaaatg
    79021 acttttcacg cgtgatcaag gcttcacgat aagttggagt gacaatttct cgttcttcca
    79081 acaagcttgc tacctgatca aagagttgtt cttgattatc cgcttctaag caaaacacaa
    79141 ggtttttgtc aaagaaataa tctaatacca taaggttttc ccttctttcc attaacttta
    79201 tgccataagt ataacactat atgaaaccgt tgtcaattac tttctgttct tttttgtctc
    79261 tttttttata tttttgtttt gtttatagtt tgttatataa aaacaaacac acaaacaaat
    79321 actccaagca tttttgctgt tctaatattc aatgaaaatc aaagagcaaa ctagaaagct
    79381 agccgcaggt tgttcaaaac actgttttta ggttgtagat agaactgacg aagtcagtga
    79441 tcatatcgta accgtccaat agacttcgtt attgggcggt tacgaaaaac ttccttccaa
    79501 ataaaaagga attaagcaac caaacgctac ttaattcctt gaaattgtct catcacctct
    79561 attagccttt aaattttgat agactctatt ttctaatcaa tatgaccaat attgtcaata
    79621 ctaacccttt caatcaattc attagttatc taaactaagt ccattaataa ctccaaatag
    79681 tatcaatagt gaagtaaact aaataattga gttataaatg gctgttttca caaaactatg
    79741 tcatcacctc actatctaat ctcagtacat aaaccatttt tttctatagc ttttatctta
    79801 atcttgattt tttttcttca atccaagaaa aattcctact ataaacatta ttccggcagc
    79861 taatagtgtc tgggctccgc ttgctgttcc agtttttggc aacttattag gattgttagt
    79921 agttgattta ctactgatat tgtttttatc aagaactgta gctgtaacat ccttagttga
    79981 atcagatttt tgtgaatgat cttctctttg taaatcctct tttctgtgac tttcatttaa
    80041 ttgactatgg tttacttgtg ggttatcttt ctttttcgat acatcaaaag taggtttatt
    80101 ttcttcctcc tttttctcct ctattttctt gaatacaggt tttataaagg tatcttttga
    80161 tagattaata acatagccag cgtctttttt accttcgaaa ccagaaattt cccaaccatc
    80221 aaattggtat cctttttcta attcaccctt ataaacaggt aaaataaaat cttcttccga
    80281 cactatcgtt gaactcattt cttttccatt ttgaatggtc acagttaccc tatgaggttt
    80341 taattcactt acctctcccg tatctttatt taaaatgaat tcttttacgg ttgtatttct
    80401 tgcaaaatct tttacaacaa tcttaatgtt tagtgtcttg tctgttattt gtttaatatc
    80461 atcaaatgat gtatattctt ttccatttat ataaatatgt tgttcttgaa tctcaccatc
    80521 gaatccatta tttcttttat cattgatgtt aaagactaca gattttccat cagcatattc
    80581 gatactagta tttcccttag gatcaatgtt tacttcgggt ttaacattat catataaaaa
    80641 ctgatagtgg actccaactg ctttagcatt caaattgcta tagccagttt gaagataaac
    80701 atttccatcc atatctgtta ccttatctgg aaatccgttt gctttatagt ctttcattcc
    80761 ccagtccatg atgtcaccgt ctttaacatt cagcttaata ttaaaatctc tagtgttatc
    80821 aatgtgtaaa tctccgtaga ttaaataatt atctacaacc gattcattaa ctctcaattc
    80881 ccagttaaaa ccacccttat cagaaatctt acctcttaaa taaaattctg gatttcgtac
    80941 ataaatttta ttagatttag atggattaaa gtagttctta tccattgaaa ggtttactgg
    81001 tttggtatca ataaataaca tggagccatc ttcttttata gcttctacat tggacttatc
    81061 ctctccagtg tattctttat catccttacc aaataataca agtttagaag aatctgtcac
    81121 aagatttccg tctttatcga tagcttcccc tttatcgttc attttaaatg taaacacttg
    81181 ataccttata atgttaaagc cgtccaaagc cgacattaat acagcttggg tacttcttcc
    81241 atcttcaaca tttctactat cagcataaat tgttgtttct gaaaggactc ttagattagg
    81301 attggccttt tgtatttttg ctatatcttc cttgctatag actccatttc cttctaacat
    81361 atccgttttt ccaggattat aggtagtcac ttttagtgca tagccttttc ttagaatgat
    81421 gttatccttt aacagatatt gttgtttttc tgaatcagaa tagattttac cagattccat
    81481 tttagttaaa ttgtctggtt tgttttttga aagatctcct tcccctaatt ctatgacatt
    81541 cccataactt gatacatagg gatattctga tttagtttcc ttaatttttt caggcattct
    81601 aattttaatt tcagcttttt tctgatcatt atctttaaca aataatctca tatctcctgc
    81661 aaaagctaat ccatccacaa tatcattaat attagcgtat agatcaaatg tcatcgtttt
    81721 tgagtggaaa tcatacttgg tcgctttgat ttctatagat ttatagttat tcccataata
    81781 taccttggca tttttagaaa cattacttat ctttccaaga atttcaaagt gtccatcttt
    81841 agacggactt agaacaccat aaatttttga tttgatttcg tcaagtttct cagtttcata
    81901 ttctagatca gtcccatcat cgtaggctat tatatttcct ttatcatcgt atttataatc
    81961 acgctctact gttcttgttc caccatttac aaagtcgtct tcttgcttat atttcttttt
    82021 aatgagtttc tttaggtctt tattttcaaa gtctctaatt gttgaaatag ttttatgaat
    82081 attaaagaga gattttcctt cgatagactg attatctact aaaaggttat tttccacctc
    82141 agctgtctct ttgtttaggc tatcatcttt aacatttttt aaattcttaa atttagattc
    82201 aggaatttcg ccaagctttt ggtatttaga tgaatcctga tcaggatcta ctagataata
    82261 ggaaatcatc cctttttcat cagcttgatt agcaaattta atcctatgga ttttggtaaa
    82321 gttgcttgct ccatctaggg cgattacttc gatgattttt cctcttagat ctcctgctcc
    82381 gctaatttca tagatagtat tcccatcttt atcaagcttc ctatttcttc cttgaccctc
    82441 acctgcataa gttacttcaa gatttttctc aacctctcca tcttcattaa caagagcagc
    82501 tcctgcatac cacacctcat ttgcaatctc atcaaatttt tcaggatgtt ctttttgatc
    82561 tctagcaaat aaagtttcat tcttgtattg atcttttacc ttgtgataag tatcctttgt
    82621 gattagctta attttttcag gatttgaaaa atcaaccgaa acaatcttag gggctgtgtt
    82681 atcaattttt acaggaatat aggaaacctg ccatgggtaa tctttagtta atctatattt
    82741 aaatttatag aaatattgac cttccgcaat cggttcaaat tgtcctcgta tcttagtagc
    82801 tggatcttgg ttatccttac tttctggggc attttcttct ctacctcttg ggttatagat
    82861 gagtccatcc catttcaagt caccccaaac ttttagtttg gatgatttga tacccttagc
    82921 gtcatttccc ttagaattta gaattcctct tatgaagtgc tctcttgata caactttaag
    82981 gtctttttgg ttttctcctt ctttgttggt gtttacaatt gaaattagtc cttcttctgc
    83041 acttcttaga acaagtggag atggagttag tcctctttct agttgagcat cttgaggatt
    83101 tccatttgaa tctaaaggat aaatgttagc aatcttagaa ccactagtgg attctgcatg
    83161 aacaccttgg ttgttaaagg caaataagtc tggatcttga tctagagatg ttctattttt
    83221 atcttttcta ttttggataa ctcctgctgg attaaattta tctataccat gttctccacc
    83281 aatcccctta tttaaggttc ctggaatttt tggtttaccg tcatcatcat aaccttccat
    83341 tgtttttgat tttgatcctt cttcccaagc ccatttatca aggattggtt cgtggttcca
    83401 attcccagca aatcccatta ggggcattga taaagatggt tggaagtcgg ttttcttgcc
    83461 attggagctt aatgcttcca tttcttctac tgactcaaaa tgaataaatg attctacaaa
    83521 tttattttta tttttagcct ccccaacatt tataaccgca tttaaatcaa agctagaatt
    83581 tgcccctata gtgaaagtgt catgctcaaa tgtaatattt gcccctttga ctttttctgg
    83641 atgaatttct ggaacaattt gcttaccatc tggagatttt tcatctttat atgtttcatc
    83701 cagttttagt ctgtcagtta gagaatctgt agtcaccgct gatgctgaaa ctttaaaggt
    83761 taaaggcctg ttggatgtat tgtgaagctt aattgtaaag tattttttat caccttttat
    83821 ttctttaaga gaaatggaac catatgaatt taccaaacct ttagaatccg tgtttttgaa
    83881 agtcgctaca acttcatttc tcaaagcgtt ggccacatta attagccccg ccccctgctg
    83941 tctaggtgat gcaaagtatt gacttttttc tttccaagaa gttgcatcca tcataggtct
    84001 tgcagtattt tgtagggcta tttttgtaag acttgtaagg tctattttat catcaccttt
    84061 aagatttttt aatacgggtt tttcaagcat ttccttcaat tttggtcgaa tcaaaacagt
    84121 agaagctgct acgattggag tcgccatact agttccggac atatagccat aagttgattt
    84181 gccattaata acattaagcg tggatttaat atttttacca ggtgctgaaa catcgggttt
    84241 taaaagtaaa tctattcttg gcccccaaga tgtggatcct gctggaacga tgatatcttc
    84301 tttatagagt tctttgtctg tgtcaggtgc aaacttaaag tcaatctctt tttcgtcacc
    84361 tacattcggt ttgttggaat taaaactttc catatcaatt ggatagtatt gctccaattt
    84421 atctttaaaa tcttctttat tatttctttt gacttcagtt tttttatcag gattaatcat
    84481 gttccatagc tttacaccat catctcctga aattgaaaac acttgacttt tagtaccttc
    84541 atccgcttca tatcccatag ctggaagctc tgtccaatta tctctattgt agtaatttac
    84601 agtatttaca accataatgg cgcgtgcacc cttatccata gcttttttaa aagcattttt
    84661 taaatccttt gtataaattc tatccattac tgcaattttg cccctaagat ccaaacctat
    84721 caaatcttgg tcttgcccct tgcctatata tacaaatttt aatttactag gagcttttgt
    84781 tccatcttca tttgttgtga ttttattctt atcgaaaaag gcccctatat ttctgtattt
    84841 aaaactttgt cctccaatgt taaccttatc aaactcaact gtttgatttt tagcagaagc
    84901 gaccgctatc gcatcttcat gtgctgcagt tcgtgttaca tttccagtgt cggtcatttt
    84961 cagatgatta tttgctacta aatcccatga agaacttgaa gcagaagtcg catagttacc
    85021 cgtagcgaca accattggaa tgcctgcttt tcttaatgcc ctaatagctt gccaatattt
    85081 ctcacctaca agacctgttc ctgtaaaacc agatgatacc gaaacaacat caacgttgtg
    85141 tttgatagaa tcttcaatag catgaaacat tgtttcatca cccgcaaacc cagatcctgc
    85201 gtcagaatac attttataag agaaaatttg tgcattaggc gcaattccat ctatgccgtt
    85261 aaagtttttg atatcttgtt cagtatcatt tccagcaaga atccctgcaa tatgcatccc
    85321 atgtgggtca aaataatccc ttccatcatc atatttttct acagtgattt tgccaccatt
    85381 ataataattg aacgcatgag ggattttatc actcaaccaa taatttttat cagttccttt
    85441 taagtcttct tttttaaatc tcattgaggc tttggcatca tcatcgattc tcatagcctt
    85501 atgcctataa tctgttccag tatcgatatt tgaaatgacc atacctctac catcaaaatt
    85561 tttcccaaac ggagcattga tagactttag gtaatcaata gcttcctcaa ctccaatttc
    85621 ctttctggca tgattcatca tgggttggac tttttgtgcc ctttcaaccg atgtaatacc
    85681 ttctatttgt ttaattttat tcagattatc ttgagttgtt tcaatagcac caccgttaaa
    85741 aattctatca taagtatata aaacttttgt attcttaaga ctggatagct ccttgattgc
    85801 tttttctcca gattctttat ctttaaattc agcaatatag acaactttat cttctttttt
    85861 gggattttct gtgtttttat tcacaaatga gtccgtatga tctccttggg atttattgga
    85921 attttcttct ttgatttttg cttcttcatt gctagtttta gtgtctatca caggattttt
    85981 actaacaact tctttttcct caataattgt tgttttcttt tcttcagtat cctgtgaagt
    86041 ttccatagca ctatggatat cttcatgttt ctctttattt tctgctactt tttctttatc
    86101 agagatgctt aaagcatctt cagagctaga tgtgtctgct aagactacct cattaggggc
    86161 ataggctgct aaaataactg cagctgtggt taatgacaat actgtacttt ttttcatttt
    86221 aattccttac atatttatat aacttccaat agataataaa ctttaacttt gctagccttt
    86281 gttataaaaa gttttactaa gtattatcta ggaaatagag tagtacattt atatataatt
    86341 gttatctctc cataaaaaca gtatatcatt taaaaaaaat taattcaaga aaaattaata
    86401 cacattaatt tattttttaa tatatgttaa aaaataatgc aaaagtttcg tacttaacag
    86461 ggatacatta taagcacatt cataccatca aaaatagtag caataaactt gaacaactac
    86521 cagaaacacg aaaacaggca taattgatga aatatcagcg ctattaaaca atataaataa
    86581 ccgctaagaa taaggcttaa cggttatctt ctacctatct attttttcaa atcctcagtc
    86641 gtttatctac ctataaccta ggctttacga gtgccttgct ctaccaacta agctaaatcg
    86701 gcgattacac ttacagtata gcactctgag aatagatgtc aagtaatatt attcaagctt
    86761 tttaatcaaa atctgacaag gattttgcgg attccatagt tgaagaaaaa tctctaactt
    86821 tttaaagcca agacctcgat aaaagtcatt tgttcgatca taatctttat tagaaccttc
    86881 tgccactgtt ttgacctgca gataaccaac ttttttacga gcttcactct ctaaagtagc
    86941 aagcaattgg ctcccaattt ttctaccttg ataagctttt ttacgccgag acaatcaatc
    87001 tctgcacaat cttcactcga ataggataag cttacaaatc cagtcaaatc actctcctga
    87061 taggcggtcc aaacttgcag tgtcgtggtt ccttctatat aggcttgtgt gctttctggg
    87121 attccaaacc attctggcaa atccttcaaa acctcagcta caactgcctt tttttgattt
    87181 tcatccttga cttcttcaat tacaaacatc ataagtttct ttcttgattt tagtcttact
    87241 ttagctttta cgaacccgca ctttcgtagg aatctaagcc cttatcccaa agtttaaggg
    87301 aaataacaaa gaaaaccaga gaaatcaaca tcaaacctcc tacgttaaag aacacatcct
    87361 tttcctgtaa gaaatagcta gctggataat aggctgtaaa ggcgaaaggc acgataaagc
    87421 taatcaacca acgaagaaga gaattgtaaa tagaaatcgg atacttagca aagtcattga
    87481 acatatagaa gatgtaaatc atggcgcctg actgcttagt ccaaaaggcg atactggctg
    87541 ttgcgatttt aagagaagta taaatcaagg tcgcaaaagg aatacaaact aggaaaagca
    87601 ggaattttgg aagagtccaa acaatgctgg tcactgttgt tcccaataaa ataccaccga
    87661 ctaagagttc acccaaggca tcaatctgaa aggtttcaac taggatgtga aagagaggat
    87721 tgatgggacg agtcagatac ttgtcaaact ctccttttcg gactaggcgt tgccctagtg
    87781 cccagagatt gtcaaaaaag agatggtcca ttcccttggg aatcaaggaa aatccataaa
    87841 tgaaagctat ctcttgaaag gtccagcctt ctaggaatgg aatatgttga aagatgacat
    87901 tgagaaacaa gagattcaag ccttgagcca gaaagactcc caagacacca accacaaaat
    87961 ccaccttata ttccatgatt tgtttgatgt attgtctgat aaaaatcaga tgcattcgtt
    88021 gatatttttt catactaacc tccttgaatg gtgataaagg actggacccg tttccaaatc
    88081 aactgagaca atcccaccat cactaagagc cagaagaact gcaaaaggag tgcctgaaga
    88141 atctgactgg catcgtattt tccaacaatg atcataactg gagtataaat caaggatgaa
    88201 aaaggcaaaa aggaaagaat atctgaaaca acctttggaa agaatgccaa gggaatcaaa
    88261 ctccccgaca taaaagccac tatggaagtc ttaagtaggt tggaacccca aagattttta
    88321 aacacaaagg ctgaaaatcc aaagcaaata ttaaagaaaa agttaatcag ataggcgagc
    88381 gttaagctaa aaagataaag gacagttaat cctagcacct ctacaatacc ttgacccgat
    88441 atgattttca tcaagacaat gacacttaaa aatggaaggc caacgctgat aaaaatcaac
    88501 cacttggaac caagctcggt gaaaagatag gaggccgcaa aatgcactgg tcgcaacaaa
    88561 cgcatgataa tggagccatc cttgacctcc tccccaatca taaaggacga atcggatcta
    88621 gtcagaagat tggtcacaaa actcatgatg atgtagaggg tgatatccgc catactgaag
    88681 ccctgaatca aagactcttg cgaagaatca aagacagcct tccagagata aaaggccaca
    88741 aaagccccca tgacatcgcc aatccgatag agaataaagt tgactcggta agtaatcaac
    88801 tcctgaaccc ctgcattgat aaagggttta taacgtctcc acaatttgat catcctagag
    88861 ctcctttcgg tagaagcgac ggataatatc ctcaatatcc gtatccacca tcttcaaatc
    88921 gcggatttca aaatcagaca gggtttgctt gataatgtca gctgactggt agcgagaact
    88981 atcaaattca atgttgaggc tgtttccttg tctatcaatg gtcatatcag acagaccttc
    89041 atagtgagag acgagatgac tttgacctgg tagcagttca aaagagagag tcttcatctt
    89101 accaaaggtc tccttgagtt ggctcaccgt tccatcaaaa atctcttgcc ccttgtcaat
    89161 catgaaaatc cgatcacaaa gttgctcaat atcactcaaa tcgtgagtgg tcaaaagaat
    89221 ggtagtttct tcctcttgat tgatctgagt aattgcccga cgaatattat ccttaaccga
    89281 aacgtccaaa ccaatggtcg gctcatctaa aaaaagaacc ttgggattgt ggagcaagga
    89341 ggccgcaata tccgcccgca tccgttgtcc cagtgaaaga gtccgcacgg gatccttgat
    89401 aaagtccttc aaatccaaga cttcattcaa aaagtccatg cgcttatgaa agagcgagtt
    89461 tggcacatca taaatctctt ttaagacagt gtaggtctct tgcagagcca aatcccacca
    89521 tagctgggtg cgttgtccaa agactacgcc aatatctttg acataatctt gccgattgtc
    89581 ctggggaatc ttgccgttaa tccgacaaaa accagatgtt ggtttcaaaa ttcctgtcag
    89641 cattttaatg gttgtcgact tcccagcacc atttgccccg ataaatccta aaatctgccc
    89701 ttttggaacc tcaaaggtca aatccttgac cgcttcaaag gtctgctttt caggatgaat
    89761 aaaggagcgc aaagccccct tcaagcccgg ttccttaaca gtcttcacaa aatttttctg
    89821 aagatgttcc acttctatca ttgccatatc tatctcccta tcgtaaggaa tagcaacatt
    89881 gtgtttttaa ctacaaatat tctaaatcct tgctttctac accttctaca ttttattact
    89941 acaaaaggct ttataccaac ctattatagt ccaataaaaa acgaaatgca agcgtttgcc
    90001 tatggattgt gaaattagga tttctctcat aaaataatac ttttaatcaa aaattctgtt
    90061 taatagttta aattaccaac ctacttatct tctcaccaga gggcggtatt aactttgatc
    90121 ataaaatcgg atactccctc tatccagaaa atatgctcag aatgattgtc tctaaacaat
    90181 acctgctctt ttacctcatt catgaaaaag aagtccatac cctgagaatt atcaactcac
    90241 gcatcgacta cctaaaccaa ctcgaccacc tctttcgtac atgtaggaaa ctattttcct
    90301 cacaaataat ctcattataa aatccaataa atttttttag ctcacttgaa tattttcttt
    90361 gtatcgtttt atcagcttca atctgatcta gacttgttac cttggaacga cttgaaataa
    90421 cctttataaa ataacactta aggctttcat catctcgtat aaatttttca atagtgatat
    90481 aaaaagcttt catattctgt ttgtaatcag atatcaattg attaatttta tcattctgat
    90541 gaagattcga taccataata tatagcggat tgaaataaga tg
//
LOCUS       DBEJNA010000004        83045 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEJNA010000004 DBEJNA010000000
VERSION     DBEJNA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.04"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..306
                     /locus_tag="ACL3JB_000285"
     CDS             <1..306
                     /locus_tag="ACL3JB_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078495769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0685091.1"
                     /translation="SASASTSASASASTSASASASTSASASASTSASASASTSVSNSA
                     NHSNSQVGNTSGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
     gene            367..2451
                     /locus_tag="ACL3JB_000286"
     CDS             367..2451
                     /locus_tag="ACL3JB_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0685092.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIISQTYKNIEIVVVNDGSTD
                     ASGEICKEFSEMDHRILYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIEQDYVET
                     LYKKIVEYQADIAVGNYYSFNESEGMFYFHISGDYYYEKVYDNVSIFENLYETQEMKS
                     FALISACGKLYKARLFEQLRFDMGKLVEDGYLNQKVYLLSEKVIYLNKGLYAYRIRKG
                     SLSRVWTEKWMHALVDAMSERITLLANMGYPLEKHLAVYRQMLEVSLANGQASGLSDT
                     AIYKEFEMKKRLLNQLTVQESSEKKAIVLAANYGYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKTDISYTVFLRYFIADFVQEDK
                     ALYLDCDLLVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDVTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEIINQFARLGKTILSFENTKTYEAGQEVYAVDQV
                     QAMIEKLREISK"
     gene            2758..3972
                     /locus_tag="ACL3JB_000287"
     CDS             2758..3972
                     /locus_tag="ACL3JB_000287"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGR0685093.1"
                     /translation="MNTKSIVFNADNDYVDKLETAIKSICCYNNCLKFYVFNDDIASE
                     WFLMMNKRLKTIQSEIVNVKIVDHVLKKFHLPLKNLSYATFFRYFIPNFVKESRALYL
                     DSDIIVTGSLDYLFDIELDGYALAAVEDSFGDVPSTNFNSGMLLVNVDTWRDEDACSK
                     LLELTNQYHETAYGDQGILNMLFHDRWKRLDRNFNFMVGMDSVAHIEGNHKWYEISEL
                     KNGDLPSVIHYTGVKPWEIISNNRFREVWWFYNLLEWSDILLRKDIISRSFEELVYSP
                     KAHTAIFTASCEMEHVEYLIENLPEVHFSILAHTYFASSVVALLRYSNVTIYPCFSPF
                     DYRKILDNLDFYLDINHYKEVDNIVSVVQQLSKPIFTFENTSHDIGNQTNIFSSTEPN
                     KMVEAIRQFIGE"
     gene            3977..4255
                     /locus_tag="ACL3JB_000288"
     CDS             3977..4255
                     /locus_tag="ACL3JB_000288"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0685094.1"
                     /translation="MADELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGGVHYFCRL"
     gene            4263..4853
                     /locus_tag="ACL3JB_000289"
     CDS             4263..4853
                     /locus_tag="ACL3JB_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HGR0685095.1"
                     /translation="MEHDALDRLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDD
                     SLEVIEGKAIMDREGVEEVRNGNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVL
                     LRASRIVYLNRCVYWYRVGLSDTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHI
                     LIYKNRLQRVIAKLEEQNMQFTEIYRRMMEKLSLLP"
     gene            4882..5892
                     /locus_tag="ACL3JB_000290"
     CDS             4882..5892
                     /locus_tag="ACL3JB_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0685096.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAEFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLFVDAIYHLG
                     VE"
     gene            5902..8346
                     /locus_tag="ACL3JB_000291"
     CDS             5902..8346
                     /locus_tag="ACL3JB_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HGR0685097.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDVVALYNNWQEHLAF
                     NDKPAVIHFTTYRKPWTTLIANRYRDLWWEFHDLEWNQILQHHIGEFEMTSPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGFESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHVDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            8377..9597
                     /locus_tag="ACL3JB_000292"
     CDS             8377..9597
                     /locus_tag="ACL3JB_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0685098.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            9606..10802
                     /locus_tag="ACL3JB_000293"
     CDS             9606..10802
                     /locus_tag="ACL3JB_000293"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGR0685099.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKTEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFVTEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVVKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNLPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMFVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELISLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            10802..11704
                     /locus_tag="ACL3JB_000294"
     CDS             10802..11704
                     /locus_tag="ACL3JB_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0685100.1"
                     /translation="MSELISVVVPIYNTGKYLVGCVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGAAQAKNMGISVAKGEYITIVDSDDIVKENMIET
                     LYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNS
                     SAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSG
                     SIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTD
                     TEEYKDICFRLKLFFDAEQRNGKS"
     gene            11761..12978
                     /gene="secY2"
                     /locus_tag="ACL3JB_000295"
     CDS             11761..12978
                     /gene="secY2"
                     /locus_tag="ACL3JB_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HGR0685101.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            12988..14568
                     /gene="asp1"
                     /locus_tag="ACL3JB_000296"
     CDS             12988..14568
                     /gene="asp1"
                     /locus_tag="ACL3JB_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HGR0685102.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHYIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            14552..16087
                     /gene="asp2"
                     /locus_tag="ACL3JB_000297"
     CDS             14552..16087
                     /gene="asp2"
                     /locus_tag="ACL3JB_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HGR0685103.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            16084..16524
                     /gene="asp3"
                     /locus_tag="ACL3JB_000298"
     CDS             16084..16524
                     /gene="asp3"
                     /locus_tag="ACL3JB_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HGR0685104.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            16517..18889
                     /gene="secA2"
                     /locus_tag="ACL3JB_000299"
     CDS             16517..18889
                     /gene="secA2"
                     /locus_tag="ACL3JB_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HGR0685105.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            18901..20412
                     /gene="gtfA"
                     /locus_tag="ACL3JB_000300"
     CDS             18901..20412
                     /gene="gtfA"
                     /locus_tag="ACL3JB_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HGR0685106.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            20405..21742
                     /gene="gtfB"
                     /locus_tag="ACL3JB_000301"
     CDS             20405..21742
                     /gene="gtfB"
                     /locus_tag="ACL3JB_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031647 - regulation of protein stability
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HGR0685107.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGTCFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHYPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKTTYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLCYPNVALY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYVAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            21744..21923
                     /gene="asp4"
                     /locus_tag="ACL3JB_000302"
     CDS             21744..21923
                     /gene="asp4"
                     /locus_tag="ACL3JB_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HGR0685108.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            21928..22152
                     /locus_tag="ACL3JB_000303"
     CDS             21928..22152
                     /locus_tag="ACL3JB_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HGR0685109.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(22388..23341)
                     /locus_tag="ACL3JB_000304"
     CDS             complement(22388..23341)
                     /locus_tag="ACL3JB_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0685110.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23409..24618)
                     /gene="sstT"
                     /locus_tag="ACL3JB_000305"
                     /pseudo
     CDS             complement(23409..24618)
                     /gene="sstT"
                     /locus_tag="ACL3JB_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24757..25317
                     /locus_tag="ACL3JB_000306"
     CDS             24757..25317
                     /locus_tag="ACL3JB_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0685111.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            25374..26282
                     /locus_tag="ACL3JB_000307"
     CDS             25374..26282
                     /locus_tag="ACL3JB_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0685112.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            26297..26824
                     /locus_tag="ACL3JB_000308"
     CDS             26297..26824
                     /locus_tag="ACL3JB_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0685113.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            26827..27933
                     /gene="yqeH"
                     /locus_tag="ACL3JB_000309"
     CDS             26827..27933
                     /gene="yqeH"
                     /locus_tag="ACL3JB_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0685114.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            28148..28459
                     /gene="yhbY"
                     /locus_tag="ACL3JB_000310"
     CDS             28148..28459
                     /gene="yhbY"
                     /locus_tag="ACL3JB_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0685115.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            28511..29140
                     /locus_tag="ACL3JB_000311"
     CDS             28511..29140
                     /locus_tag="ACL3JB_000311"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0685116.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQLVLDYIEKEGLY"
     gene            29140..29733
                     /gene="yqeK"
                     /locus_tag="ACL3JB_000312"
     CDS             29140..29733
                     /gene="yqeK"
                     /locus_tag="ACL3JB_000312"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0685117.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            29734..30234
                     /locus_tag="ACL3JB_000313"
     CDS             29734..30234
                     /locus_tag="ACL3JB_000313"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0685118.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEGWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            30247..30600
                     /gene="rsfS"
                     /locus_tag="ACL3JB_000314"
     CDS             30247..30600
                     /gene="rsfS"
                     /locus_tag="ACL3JB_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0685119.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            30709..31449
                     /locus_tag="ACL3JB_000315"
     CDS             30709..31449
                     /locus_tag="ACL3JB_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0685120.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNVLNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            31459..32556
                     /locus_tag="ACL3JB_000316"
     CDS             31459..32556
                     /locus_tag="ACL3JB_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0685121.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAQQNFGRVPIRIETN"
     gene            32794..33048
                     /locus_tag="ACL3JB_000317"
     CDS             32794..33048
                     /locus_tag="ACL3JB_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR0685122.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            33052..33306
                     /locus_tag="ACL3JB_000318"
     CDS             33052..33306
                     /locus_tag="ACL3JB_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGR0685123.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            33497..35110
                     /locus_tag="ACL3JB_000319"
     CDS             33497..35110
                     /locus_tag="ACL3JB_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0685124.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            35240..35866
                     /gene="gmk"
                     /locus_tag="ACL3JB_000320"
     CDS             35240..35866
                     /gene="gmk"
                     /locus_tag="ACL3JB_000320"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0685125.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            35891..36205
                     /gene="rpoZ"
                     /locus_tag="ACL3JB_000321"
     CDS             35891..36205
                     /gene="rpoZ"
                     /locus_tag="ACL3JB_000321"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0685126.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            36271..38667
                     /locus_tag="ACL3JB_000322"
     CDS             36271..38667
                     /locus_tag="ACL3JB_000322"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0685127.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVFGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            38680..39615
                     /gene="fmt"
                     /locus_tag="ACL3JB_000323"
     CDS             38680..39615
                     /gene="fmt"
                     /locus_tag="ACL3JB_000323"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0685128.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDNRYEILAVATQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            39608..40921
                     /gene="rsmB"
                     /locus_tag="ACL3JB_000324"
     CDS             39608..40921
                     /gene="rsmB"
                     /locus_tag="ACL3JB_000324"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0685129.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGIEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            40936..41676
                     /locus_tag="ACL3JB_000325"
     CDS             40936..41676
                     /locus_tag="ACL3JB_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0685130.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFRTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            41673..43652
                     /gene="stkP"
                     /locus_tag="ACL3JB_000326"
     CDS             41673..43652
                     /gene="stkP"
                     /locus_tag="ACL3JB_000326"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0685131.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            43767..44525
                     /locus_tag="ACL3JB_000327"
     CDS             43767..44525
                     /locus_tag="ACL3JB_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0685132.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            44527..44976
                     /locus_tag="ACL3JB_000328"
     CDS             44527..44976
                     /locus_tag="ACL3JB_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0685133.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            45038..45664
                     /locus_tag="ACL3JB_000329"
                     /pseudo
     CDS             45038..45664
                     /locus_tag="ACL3JB_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            45732..45980
                     /locus_tag="ACL3JB_000330"
     CDS             45732..45980
                     /locus_tag="ACL3JB_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685134.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            46111..47283
                     /locus_tag="ACL3JB_000331"
     CDS             46111..47283
                     /locus_tag="ACL3JB_000331"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0685135.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            47283..48557
                     /locus_tag="ACL3JB_000332"
     CDS             47283..48557
                     /locus_tag="ACL3JB_000332"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0685136.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNDQEYTVPYVTEEPSVVAAASYAIKIIKRTGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(48592..49557)
                     /locus_tag="ACL3JB_000333"
     CDS             complement(48592..49557)
                     /locus_tag="ACL3JB_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0685137.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(49538..50992)
                     /locus_tag="ACL3JB_000334"
     CDS             complement(49538..50992)
                     /locus_tag="ACL3JB_000334"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGR0685138.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            51369..53252
                     /locus_tag="ACL3JB_000335"
     CDS             51369..53252
                     /locus_tag="ACL3JB_000335"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0685139.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            53399..54286
                     /gene="scrK"
                     /locus_tag="ACL3JB_000336"
     CDS             53399..54286
                     /gene="scrK"
                     /locus_tag="ACL3JB_000336"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0685140.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(54606..55223)
                     /locus_tag="ACL3JB_000337"
     CDS             complement(54606..55223)
                     /locus_tag="ACL3JB_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0685141.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(55638..55851)
                     /locus_tag="ACL3JB_000338"
                     /pseudo
     CDS             complement(55638..55851)
                     /locus_tag="ACL3JB_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(56219..56410)
                     /locus_tag="ACL3JB_000339"
     CDS             complement(56219..56410)
                     /locus_tag="ACL3JB_000339"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685142.1"
                     /translation="MKIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            56533..57426
                     /locus_tag="ACL3JB_000340"
     CDS             56533..57426
                     /locus_tag="ACL3JB_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685143.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLADKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            57423..58622
                     /locus_tag="ACL3JB_000341"
     CDS             57423..58622
                     /locus_tag="ACL3JB_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685144.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(58975..59742)
                     /locus_tag="ACL3JB_000342"
     CDS             complement(58975..59742)
                     /locus_tag="ACL3JB_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685145.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(59759..60454)
                     /locus_tag="ACL3JB_000343"
     CDS             complement(59759..60454)
                     /locus_tag="ACL3JB_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685146.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(60459..60824)
                     /locus_tag="ACL3JB_000344"
     CDS             complement(60459..60824)
                     /locus_tag="ACL3JB_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0685147.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            60964..61437
                     /gene="nrdR"
                     /locus_tag="ACL3JB_000345"
     CDS             60964..61437
                     /gene="nrdR"
                     /locus_tag="ACL3JB_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0685148.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            61438..62607
                     /locus_tag="ACL3JB_000346"
     CDS             61438..62607
                     /locus_tag="ACL3JB_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0685149.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKIQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            62608..63504
                     /gene="dnaI"
                     /locus_tag="ACL3JB_000347"
     CDS             62608..63504
                     /gene="dnaI"
                     /locus_tag="ACL3JB_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0685150.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            63501..64214
                     /locus_tag="ACL3JB_000348"
     CDS             63501..64214
                     /locus_tag="ACL3JB_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0685151.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYPVFGMAL
                     GVPNQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            64228..65538
                     /gene="der"
                     /locus_tag="ACL3JB_000349"
     CDS             64228..65538
                     /gene="der"
                     /locus_tag="ACL3JB_000349"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0685152.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            65627..65962
                     /locus_tag="ACL3JB_000350"
     CDS             65627..65962
                     /locus_tag="ACL3JB_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685153.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            66102..66437
                     /locus_tag="ACL3JB_000351"
     CDS             66102..66437
                     /locus_tag="ACL3JB_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685154.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            66622..67413
                     /locus_tag="ACL3JB_000352"
     CDS             66622..67413
                     /locus_tag="ACL3JB_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685155.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVSYMVLEKYEDNV"
     gene            67406..68047
                     /locus_tag="ACL3JB_000353"
     CDS             67406..68047
                     /locus_tag="ACL3JB_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685156.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            68051..68683
                     /locus_tag="ACL3JB_000354"
     CDS             68051..68683
                     /locus_tag="ACL3JB_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685157.1"
                     /translation="MRLEIINGQKIYRKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            68711..68998
                     /locus_tag="ACL3JB_000355"
     CDS             68711..68998
                     /locus_tag="ACL3JB_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685158.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITLAILPIFGN"
     gene            69144..71657
                     /gene="secA"
                     /locus_tag="ACL3JB_000356"
     CDS             69144..71657
                     /gene="secA"
                     /locus_tag="ACL3JB_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0685159.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMTALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            71738..72769
                     /locus_tag="ACL3JB_000357"
     CDS             71738..72769
                     /locus_tag="ACL3JB_000357"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0685160.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            72771..73802
                     /locus_tag="ACL3JB_000358"
     CDS             72771..73802
                     /locus_tag="ACL3JB_000358"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0685161.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            73847..74209
                     /gene="acpS"
                     /locus_tag="ACL3JB_000359"
     CDS             73847..74209
                     /gene="acpS"
                     /locus_tag="ACL3JB_000359"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0685162.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            74199..75302
                     /gene="alr"
                     /locus_tag="ACL3JB_000360"
     CDS             74199..75302
                     /gene="alr"
                     /locus_tag="ACL3JB_000360"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0685163.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPSGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            75321..77336
                     /gene="recG"
                     /locus_tag="ACL3JB_000361"
     CDS             75321..77336
                     /gene="recG"
                     /locus_tag="ACL3JB_000361"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0685164.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRIQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            77652..78632
                     /locus_tag="ACL3JB_000362"
     CDS             77652..78632
                     /locus_tag="ACL3JB_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0685165.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            79482..79709
                     /locus_tag="ACL3JB_000363"
     CDS             79482..79709
                     /locus_tag="ACL3JB_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685166.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            79997..82894
                     /gene="nanA"
                     /locus_tag="ACL3JB_000364"
     CDS             79997..82894
                     /gene="nanA"
                     /locus_tag="ACL3JB_000364"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0685167.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNNQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        25171 a        14928 c        18558 g        24388 t
ORIGIN      
        1 tcagcttcag cgtcaaccag tgcttcggct tcagcgtcga caagtgcatc ggcttcagca
       61 tcaacgagtg cgtcggcttc agcaagtacc agtgcgtcag cttcagcaag tacatcagtt
      121 tcaaattcag caaaccattc gaactcacaa gttggaaata cttctggatc gacaggtaaa
      181 tcccaaaaag aattgcctaa tacaggtact gagtcgtcaa ttggatctgt gttacttgga
      241 gttctagcag ctgttacagg tattggattg gttgcgaaac gccgtaaacg tgatgaagaa
      301 gagtaagaca acctgtaaag ttaggctaaa ctaactcgcg cacataaatc aaggagaaaa
      361 ttgctagtgg atgataaaat tacggtcatt gtaccagtat acaatgtaga aaactatctg
      421 aggaaatgtc tagatagtat tatttctcaa acatataaaa atattgagat tgttgtcgtt
      481 aatgatggtt ctacggatgc ttcaggtgaa atttgtaaag aattttcaga aatggatcac
      541 cgaattctct atatagaaca agaaaatgct ggtctttctg ccgcacgaaa caccggtctg
      601 aataatatgt ccggaaatta tgtgaccttt gtggactcgg atgattggat tgagcaagat
      661 tatgtagaaa ctctatataa aaaaatagta gagtatcagg ctgatattgc agttgggaat
      721 tactattctt tcaacgaaag tgaaggaatg ttctactttc atatatcagg agactactat
      781 tatgagaagg tatatgacaa tgtttccatc tttgagaact tgtatgaaac tcaagaaatg
      841 aagagttttg ctttgatatc tgcttgtggt aaactctata aggcaagatt gtttgagcag
      901 ttgcgctttg acatgggtaa attagtagaa gatggttacc tcaatcaaaa ggtatattta
      961 ttatcggaaa aggtaattta tttaaataaa ggtctttatg cttatcggat tagaaaaggt
     1021 agtctatcaa gagtttggac agaaaagtgg atgcacgcct tagttgatgc tatgtctgaa
     1081 cgtattacgc tactagctaa tatgggatat cctctagaga aacacttggc agtttatcgt
     1141 cagatgttgg aagtcagtct cgccaacggt caagctagtg gtttatctga cacagcaata
     1201 tataaagagt ttgaaatgaa aaaaagactt ttaaatcagt taacggtaca agaatcaagt
     1261 gaaaagaaag ccattgtcct agcagcaaac tatggctatg tagaccaagt tttaacgaca
     1321 atcaagtcta tttgttatca taatcgttcg attcgttttt atctgattca tagcgatttt
     1381 ccaaatgaat ggattaagca attaaataag cgcttagaga agtttgactc agaaattatt
     1441 aattgtcggg taacttctga gcaaatttca tgttataaaa cggatattag ttacacagtt
     1501 tttttacgct atttcatagc tgatttcgtg caagaagata aggccctcta cttggactgt
     1561 gatttacttg taacgaaaaa tcttgatgat ttgtttgcta cagacttaca agattatcct
     1621 ttggctgctg ttagagattt tgggggcaga gcttattttg gtcaagaaat ctttaatgcc
     1681 ggtgttctct tggtaaacaa tgctttttgg aaaaaagaga atatgaccca aaaattaatt
     1741 gatgtaacca atgaatggca tgataaggtg gatcaggcag atcagagcat cttgaatatg
     1801 ctttttgaac ataaatggtt ggaattggac tttgattata atcatattgt cattcataaa
     1861 cagtttgctg attatcaatt gcctgagggt caggattatc ctgctattat tcactatctt
     1921 tctcatcgga aaccgtggaa agatttggcg gcccaaacct atcgtgaagt ttggtggtac
     1981 tatcatgggc ttgaatggac agaattggga caaaaccatc atttacatcc attacaaaga
     2041 tctcacatct atccaataaa ggaacctttc acttgtctaa tctatactgc ctcagaccat
     2101 attgaacaaa ttgagacatt ggttcaatcc ttgcctgata ttcagtttaa gatagcagct
     2161 agagtaatag ttagtgatcg attggctcag atgacaattt atccaaacgt gactatattt
     2221 aacggaattc actatttggt agatgtcgat aatgaattgg tagaaaccag tcaagtactt
     2281 ttagatatta atcatggtga aaaaacagag gaaattatca atcaatttgc aagacttgga
     2341 aaaactattt tgtcctttga aaataccaaa acctatgaag caggtcagga ggtatatgct
     2401 gttgaccaag ttcaagcaat gattgagaaa ttgagagaaa taagcaaatg aagaaaaatc
     2461 atttagtagg agatgctctg attttgacgg ttagtgatca gattgaagag ttggattatt
     2521 ttttataaaa tttctccgtt catcatatat gaaagttgtt caaacatcag agtgctttat
     2581 aaaatataaa tagacctaaa gatatttaat atgaactgca ccccaaaagt tagacagaaa
     2641 aaatctaact ttttggggtc agtacaatat tagggtgtga ttaattatct ttttaggtga
     2701 aaatgattct atattatagc tgtttgatac gaaatttatt ataaggaaat tatgttaatg
     2761 aatacaaaat ctatagtttt taatgcagat aatgattatg tagataaatt agaaactgca
     2821 attaaatcta tttgttgtta taataattgt ttaaaatttt atgtatttaa tgatgatatt
     2881 gcgtcagagt ggtttttgat gatgaataag cgattgaaga ctatacaatc tgaaatcgtt
     2941 aatgtaaaga ttgtagatca tgttcttaaa aagtttcatt taccgttaaa gaatttaagt
     3001 tatgccactt tctttcgtta ttttatacct aattttgtca aagaaagtcg tgctttatac
     3061 ctagattctg acatcattgt tacaggaagt ttagactatt tatttgatat agaactagat
     3121 ggttatgcct tggcagcagt agaagattct tttggtgatg ttccttctac caattttaac
     3181 tccggaatgt tattagttaa tgtagatact tggagagatg aagatgcttg ttcgaaactg
     3241 ttagaactga ccaatcaata tcatgaaaca gcatatggag atcaaggaat tttaaatatg
     3301 ttattccatg atagatggaa aagattagac cgaaatttta attttatggt ggggatggat
     3361 agcgtcgcac acatagaagg aaatcataaa tggtatgaga tttctgagtt gaaaaatgga
     3421 gatttaccta gtgttataca ttatactggg gtaaaacctt gggaaataat ttccaataat
     3481 cgctttagag aagtttggtg gttttataat ctgttagaat ggtctgatat tttattgaga
     3541 aaagacatta ttagtcgtag tttcgaagaa cttgtataca gtcctaaagc tcatacagca
     3601 atttttacag ctagttgtga gatggagcat gtagaatatt tgatagaaaa tttaccagag
     3661 gtacattttt ctatactagc acatacatat tttgcgtcta gtgtcgttgc tttattaaga
     3721 tatagcaatg ttacgattta tccttgtttt tctccatttg attatcgaaa aattttggat
     3781 aatttagatt tttatttaga tattaatcat tataaagaag tggataatat tgtatccgtt
     3841 gttcaacaac tatctaaacc aatttttacc tttgaaaata ctagtcatga tataggcaat
     3901 caaactaata tattttcttc aaccgaacca aacaaaatgg tagaggctat tagacaattt
     3961 ataggagaat aagtttatgg cagacgaact aattagtatt gtagttccaa tctacaatgt
     4021 tgagaattat ttgcgaatgt gtttggatag cattcagaat cagacgtatc aaaattttga
     4081 gtgtttatta atcaatgatg gctctccaga tcattcatcc aaaatatgtg aagaatttgt
     4141 agagaaagat tctcgtttca aatattttga gaaagcaaac ggcggtcttt catcagctcg
     4201 taacctaggt attgaatgtt cggggggggg cgtacattac ttttgtagac tctgatgatt
     4261 ggttggaaca tgatgcttta gaccgattat atggtgcttt gaaaaaggaa aacgcagata
     4321 ttagtatcgg gcgttataat tcttatgatg aaacacgcta tgtgtatatg acttatgtta
     4381 cggatccaga tgattctctg gaagtgatag aaggtaaagc aatcatggat agggaaggtg
     4441 tcgaagaagt cagaaatggg aactggactg tagctgtctt gaagttattc aagagagagt
     4501 tactacaaga tttaccattt cctataggaa aaattgcaga ggatacttac tggacatgga
     4561 aggtacttct aagagcttcg aggatagtct atttgaatcg ttgtgtttac tggtaccgtg
     4621 ttggtttatc tgatacttta tcgaatacat ggagtgaaaa gcgtatgtat gatgaaattg
     4681 gggctaggga agaaaagata gctattttag caagttcaga ctatgacttg accaatcata
     4741 ttttgattta taaaaataga ttacaaagag tgatagcaaa attagaagaa caaaatatgc
     4801 agttcacaga gatttataga agaatgatgg aaaaattgtc tttacttccg tagatagtaa
     4861 taaaaaatga gatagcgtaa tatgaaatta catttaacaa atttatacgg catggctggt
     4921 gatagtacgg ttatcttagc tcaaaatgct gttcaaaaga tagctagtca actgggattt
     4981 agagaggttg gtatttattt ttacaacatt gcttcagata gtccttctga aatgaataag
     5041 cgtctggatg gtattatggc cagtatctct attggggata ttttagtctt tcagtctcca
     5101 acctggaatg gctttgaatt tgatcgtctc ttgtttgaca agctaaagga tatgcaggtg
     5161 aaaattattt gttttatcca tgatgttgtt cccctcatgt ttgatagtaa ctattatctc
     5221 atgaaagact atatgtacat gtataatcta tcagatgttt tgatagtgcc atcagagaga
     5281 atgaaaacac gcctgatgga agaaggattg acgactaaga agattcttgt tcaagggatg
     5341 tgggatcatc ctcatgattt atccttatac acccctgctt ttaaaaaaga actttttttt
     5401 gctggaagtt tagagcgttt tccagactta caaaattggt ctcaagatac gcctttgaga
     5461 gtattttcaa ataaagggga agctagttct agtgctagaa atctcagcat cgaaggatgg
     5521 aaaaaagatg aggaattgtt gctagaatta tcaaagggtg gatttggcct tgtctgggga
     5581 acccatcaaa atgagggaga aagtaaccaa tactatacct tgaatatatc tcataaggtg
     5641 agtacctatc tgacagcggg catcccagtc attgtaccaa gtagcttgtc aactgctgaa
     5701 tttatagtag atcaaggctt aggctttgtg gcgaatagtc tagaggaagt tcatgagata
     5761 gttgataaaa tgaatctaca agaatatcaa gaaatgacga atcggataaa aacctttagt
     5821 tatttgctaa aagaaggtta ttttactaaa aaattatttg tagatgcaat ttaccatttg
     5881 ggagttgaat aagagaacaa gatgattaaa acaattgtat tagctggtga tcgtaattac
     5941 atcaggcagt tagaaacaac cataaaatct attttatacc acaatcgaga tgttaagatt
     6001 tatattttaa atcaagatat tatgccagat tggtttcgca aaccacgaaa aatagctcgc
     6061 atgttaggta gtgagattat cgatgttaaa ctacctgaac aaactgtgtt tcaagattgg
     6121 gaaaagcaag atcacattag tagcattacc tatgctagat attttattgc agattatatc
     6181 caagaagata aggttttata tttagacagt gatttgattg taaatacttc tttagagaaa
     6241 ttatttagta tttgtttaga agaaaaatca ctcgcagcag ttaaagatac agatggaatt
     6301 acatttaatg caggtgtttt attaatcaac aataaaaaat ggcgtcaaga gaaattaaaa
     6361 gaacgactaa ttgaacagag cattgttaca atgaaggaag ttgaagaagg ccgtttcgag
     6421 cattttaatg gtgatcaaac gatttttaat caggtcttgc aagatgattg gttagaacta
     6481 ggtagagctt ataatttaca agtaggacat gatgtggttg ctttgtataa taattggcag
     6541 gaacatctgg cttttaacga taaaccagcg gtgattcatt ttacgaccta cagaaagcca
     6601 tggactacct tgatagccaa tcgttaccgt gatttatggt gggaatttca tgatttggag
     6661 tggaatcaaa ttttacaaca ccatatagga gagtttgaaa tgacatcgcc tctagataag
     6721 gaattttctt gtttaacttt gacaaattcc caagatttag aaggaataga agagctagtt
     6781 acagctctac ctgaggtggt atttcatatc gcagcttgga cggatatggg agataaatta
     6841 aaaaaattag ctgtatataa taatgtgaga ttgcatccac aaattgttcc tcctgtatta
     6901 gataagctga aaaagtcaac aaatctatat ttggatatca atcatggtag tgcagatgag
     6961 aactttttaa aatctttgca agaacaagaa aaaacgctac tagcttttca atcgactcag
     7021 cacggagagt taggacaaat cgttttcgaa aatgggaaag tttcctttat gattgatacg
     7081 attaaagatt ttaagaaaaa cggacatctt acctgttttc gacaacttcc aagtttaact
     7141 tgtttaacgt ttacggcttc tcaggatatc gaacaattgg attacttggc tggacagttg
     7201 ccaaatgttg tttttcaagt tgctgcttgg acagctatgg ggccaaaatt atatgatttg
     7261 tctaatcgtt atcctaatat tcagctctat ccggcaattt ctagagataa gctagacgag
     7321 ttgaaggaga agatggatgc ttatttagat atcaacctac tgacttcaac atccgatatc
     7381 gttgcagaaa tggctcatct atctaaacct atactagcct tttataaatc tcaaaatggg
     7441 aataatggcc aaaggttgta ttcaagtgaa catcctgaac gaatgttggc tgatttgcaa
     7501 aaattgataa ctaaggatat gctagaaaaa ccgcttgata taatccaggt gaaagggata
     7561 gatgaaacct tggattatat tattgaacac aactcttctt tagttcgttt tggagacgga
     7621 gaagtcaatt tgatgtgggg tttgcctata ccttatcaaa atcatgatct agagttagct
     7681 aaccaattaa aacatattgt gggttttgaa agtgacgaga aattagtggt ttgtttacct
     7741 gatgcttttg acgatcgttt tgtctttact tggtgggcta caccattctg gaaagaacat
     7801 atgaatgttt atatggattt ttataaagag ttgtgtaagg gttcatggta tggctccacc
     7861 tttatctcgc gtccatacat tgattatgaa gataagagta aggcaaaagg acaatttgaa
     7921 aagctaaaga gtatttggga gaatagggat attctgattg tagaggggat tacatctcgc
     7981 tctggggttg gaaatgattt atttgataag gtcaaatctg tgaaaaggat tatttgtcca
     8041 tctcataatg cttattccgt tgtcgataac attcaagagg aaattatgaa acatgctgaa
     8101 ggaagactga ttttatgtat gctgggtcct acagcaaaag ttctgagtta taatctatgc
     8161 cagatgggct atcaagtttt ggatgtaggc catgttgact cagagtatga atggatgaaa
     8221 atgggagcta aaactaaggt taaattttct cataaacata ctgcagaaca taatttcgac
     8281 caagatattg aatttattga tgatgaaacc tataacagtc agattgttgc acgaatatta
     8341 aactagacta tttaaaataa atgataagga tttaaaatga gaaataccaa acgcgctgta
     8401 gtatttgcag gtgattacgc ttatattcga caaatcgaaa cggcgatgaa gtcactctgt
     8461 agacacaata gtcatttgaa aatttatctg ctaaatcagg acattcctca ggaatggttt
     8521 agtcaaataa gaatatattt acaagagatg gggggcgact tgattgactg caagttaatt
     8581 ggctcacagt ttcaaatgaa ttggtctaat aaattacctc atatcaatca tatgacattt
     8641 gcacgctatt ttattccaga ttttgtaaca gaagataaag ttctctatct agatagtgat
     8701 ttgattgtga ctggtgattt gaccgatttg tttgaattag acttaggtga aaattatttg
     8761 gcagcagctc gttcttgctt tggagcagga gtcggcttca atgctggtgt tctcttgatt
     8821 aacaacaaaa aatggggatc tgaaactatt cgacaaaaat tgattgactt aacagaaaaa
     8881 gaacatgaga atgtggaaga aggagaccag tcaattttga atatgttgtt taaagatcaa
     8941 tatagttccc ttgaagatca atataatttt caaataggat atgattatgg ggcggcagcc
     9001 tttaaacatc aattcatttt tgatattccg ctcgaaccac tgccactaat tttacactat
     9061 atttctcagg ataagccttg gaatcaattt tctgttggac gtctaagaga agtttggtgg
     9121 gaatactctt tgatggattg gtctgttatt ttaaatgaat ggttttcaaa gagtgtgaag
     9181 taccctagta aatcacaaat atttaagttg caatgtgtta atttaacgaa ttcttggtgt
     9241 gtcgagaaaa tcgattattt ggcggagcaa ttgccagaag ttcattttca tattgttgct
     9301 tatacaaata tggcaaatga actactagct ttaacgcgtt ttcctaatgt taccgtatat
     9361 ccaaattcct taccaatgtt attggaacaa atagtaatag cttcagattt gtatttggat
     9421 ttgaatcatg atcgaaaatt agaagatgca tatgagtttg tgcttaagta caaaaaacca
     9481 atgatagctt tcgacaatac ttgctctgaa aatctttctg agatttcata tgaaggtatc
     9541 tatccaagct ccattccgaa aaaaatggtt gcagcaatca gatcttacat gaggtagaga
     9601 acagtatgag aaaatcaata gtattagcgg cagataatgc ctatcttatt cctttagaga
     9661 cgactataaa gtctgtattg tatcacaata gagatgttga tttttatatt ctcaacagtg
     9721 atatagctcc tgaatggttt aaattattgg ggagaaaaac ggaagttgtg aattctacaa
     9781 ttcgcagtgt acacattgat aaagaacttt ttgaaagcta taaaacagga cctcatataa
     9841 attatgcttc ttactttaga ttttttgtga cagaagtggt tgaatctgat agggtattgt
     9901 atctggattc cgatatcatt gtaactgggg aactagctac tttgtttgag atagatctca
     9961 aaggatattc aattggtgct gttgatgatg tctatgccta tgaaggacga aaatctggat
    10021 ttaatgctgg tatgttacta atggatgttg taaaatggaa agaacattct attgtcaata
    10081 gtttattgga attagcggcc gagcagaatc aagttgttca tcttggggat cagagtattt
    10141 taaatattta ttttgaggat aattggctag cgttagataa aacatataat tatatggtgg
    10201 gtgttgatat ttatcacctt gctcaagaat gtgaacgtct agatgacaat ctacctacaa
    10261 ttgttcacta tgctagtcat gataaacctt ggaatacata tagtatatct agactacgtg
    10321 aattatggtg ggtttataga gatttggatt ggtcagagat tgcttttcaa cgttccgatt
    10381 taaattattt tgaaagaagc aatcagtcta aaaaacaagt gatgtttgtg acatggagtg
    10441 cagatataaa acatttagag tatttagtac aacggttacc tgattggcat tttcatttgg
    10501 ctgcaccgtg tgattgttct gaggagctga tctctctatc acagtatacg aatgtaacag
    10561 tatatcaaaa tgtattacat agtagaattg attggctatt ggacgattct atagtttatt
    10621 tagatattaa tacaggtgga gaggttttta atgtagttac aagggcacaa gaaagtggca
    10681 agaaaatctt cgcttttgat atcacacgta aaagtatgga tgatggactc tatgacggta
    10741 ttttttctgt ggagagacca gatgatttag tggatagaat gaagaatata gagatagagt
    10801 aatgagtgaa ttaattagtg ttgtggtacc gatatacaat acgggaaaat atttagtggg
    10861 gtgtgtcgag catattctga agcaaaccta tcaaaatata gaaattattt tagttgatga
    10921 cggttctacg gataattctg gggaaatttg tgatgctttt atgatgcaag ataatcgtgt
    10981 gcgagtattg catcaagaaa ataagggggc agcacaagct aaaaatatgg ggattagtgt
    11041 agctaaggga gagtacatca cgattgttga ttcagatgat atcgtaaaag aaaatatgat
    11101 tgaaactctt tatcagcaag tccaagaaaa ggatgcagat gttgttatag ggaattacta
    11161 taattatgac gaaagtgacg ggaattttta tttttatgta acagggcaag atttttgcgt
    11221 cgaagaatta gctatacaag aaattatgaa ccgtcaagca ggagattgga aattcaatag
    11281 ctcggccttt atattgccga catttaagtt gattaaaaaa gaattattca atgaagttca
    11341 cttttcaaat ggtcgccgct ttgatgatga agcaactatg catcgctttt atcttttagc
    11401 ctctaaaatc gtctttataa acgataatct ctatctgtat agaagacgtt caggaagcat
    11461 catgagaacg gaatttgatc tttcctgggc aagagatatt gttgaagtgt tttctaagaa
    11521 aatatcggat tgtgtcttgg ctggtttgga tgtctccgtt ctgcgtattc gatttgtcaa
    11581 tcttttaaaa gattataagc aaactttaga ataccatcaa ttaacagata ctgaggaata
    11641 taaagatatt tgtttcagat taaagttgtt ttttgatgca gaacaaagaa atggtaaaag
    11701 ttgaaataaa agaattgtta tttaccatat cacaaacaat gaaggtgagg ggagtgtttt
    11761 atgactaaga tttattcgtc aatagcagta aaaaaaggac tatttacctt atttctactg
    11821 tttatctatg tattgggaag tcgtattact ctcccttttg ttgacctaaa tactaaagat
    11881 tttttaggag gttcaacagc ctatctagcc ttctcagccg ccctaacagg tggaaatcta
    11941 agaagtttgt caattttttc tgttggattg tccccttgga tgtcagctat gattttatgg
    12001 cagatgtttt ctttttctaa acggttgggt ttaacatcta cgtctataga aatacaagat
    12061 cgccgtaaaa tgtacctgac cttgatgata gctgtcattc aatcattggc agttagcttg
    12121 agactgccag tacaatcctc ctattctgca atattggttg ttctaatgaa tacaatattg
    12181 ctgatagcag gaacattttt tcttgtttgg ttgtcagatt taaatgcgag tatggggatt
    12241 ggaggttcta tagtcattct cctatccagt atggttttaa atattcctca ggatgttttg
    12301 gaaacatttc agacagtaca cattccaaca gggattattg tgttacttgc tttattaacc
    12361 cttgtctttt cttatttact tgcccttatg tatcgagctc gctatttggt tcctgttaat
    12421 aaaattggct tacacaatcg atttaaacgc tattcttatc tcgaaatcat gttgaatcct
    12481 gcaggtggga tgccttatat gtatgtgatg agttttctta gtgtaccagc ttatttgttc
    12541 atcttgttgg gatttatttt ccctaatcat tcagggttag cggctttatc aaaggaattt
    12601 atgattggaa agcctttgtg ggtctatgtt tatatttcgg tcttattttt atttagtatc
    12661 atttttgctt ttgttacgat gaatggagaa gagattgcag accgtatgaa aaaatctgga
    12721 gaatacattt atggtattta tccaggtgcg gatactagtc gatttattaa tcgattggtc
    12781 cttcgtttct cagtcatagg tggtctcttt aatgtggtta tggcaggtgg tcccatgctt
    12841 tttgttttgt ttgatgaaaa gttattacga ttggcaatga ttccaggttt gtttatgatg
    12901 tttggaggca tgatttttac gattagagac gaggtcaagg ctttaaggct aaatgagacc
    12961 tatagacctt tgatttagga gacttttatg tattatttta ttccagcttg gtatgggtca
    13021 gaaagaacat ggcatgcaga tatcactcca tggtattttt ctcattttcg tctagagttt
    13081 gatgatacct ttcaccagat tcggctcttt caagagcaag atatagattc tcgtctatta
    13141 gtattagctt accagcctca tctacgttat tttttatata gacatggtgt gttagaaacg
    13201 gatacttatt ccgtttttga tgttatgcaa gattttcata atctccatac ccaagtttta
    13261 agcattagag atattgagtg ggatgatgac tgtgaattta tttatagtcc ctttacgatt
    13321 atcgttcaaa aaaatgggaa gaaatttgct aaggttgaac atggagttga aggcttcatc
    13381 agtgatatac agtattttgg accgaatggt caaatacata tgcactatat catggatgat
    13441 cgagggttta tatcgagtat tatttttttt gaagatgggc aagcagccta tcaagaatat
    13501 ttgaatccta agggagtttg gcaatttaga gagcgtttaa aagaaggagg acaggtagaa
    13561 gtcaatccaa ttttgggtta tcgctttaaa atgcttacct atcaaaatat gggagatctg
    13621 gtggcagaat tttttgagaa ttatctgcaa acgtatgtga aggatcagga tatttttatg
    13681 cttccttctc attctcatca tgaccagttg gtactagatc gtttacctag tactaatcct
    13741 aaactgttga gtctgttcat tggacgtaat cctcaagata cctttaggga tttagatgta
    13801 acttttgaaa aatcggattt gattttggtg gatagagagg atagtttacg attgttgcag
    13861 gagttgtatc ctgaacgaat gcatcaatgt tatcatttat catcttttga cacccgatta
    13921 cgattgggac gaagccaaac taagaaagaa tccatcattt attttcaact ggattttgag
    13981 caggggattg ataatcaagc tctgcttcaa gtcttgtcct ttgtcgctga aaataaggat
    14041 actgaggtga tttttggagc ctttgctgct agtcaggagc aaatgaatga ggttgaaggg
    14101 attgttgagt ctttcatcca agaaaacatt caatccgaaa atctgggaaa ggcgattgat
    14161 tatggtgatg cagaaaatcc tctggaagaa aatcaacacc aggacttacg cttacagttt
    14221 gttaacttga atgatgagtt agatttgata aaaacactag aatttgtccg tttgattgtg
    14281 gatttaaata gacatcctca tctctacaca cagattgctg ggattagtgc aggaattcct
    14341 caaatcaacc tagttgaaac cgtctatgtt gaacatttaa aaaatggtta tttgttagca
    14401 gatgttacag aattttctaa ggctgcacat tattacacag ataggttgaa ggagtggaat
    14461 gagtccttga tatattcaat tgataagatt aaggagcaca caggacaaca atttcttgga
    14521 aaattagaga aatggataga ggaggttaaa aatgtcaaag gaacttaata ttttacagat
    14581 aggacttgcc aattgggaaa atcactatga catacctgaa aatatgagtt ggtattattt
    14641 ttacccaaac tcatcaaaag cccttcgtga aataattgaa aaagaggata ttaaccgttt
    14701 tcatgcagtt ttaatagaag atggtcagta ttccagagac ttattttcct atgtaaaata
    14761 ttttgaacct tatactttgt tctataacca gaatctacaa ataaatgata gagaggttgt
    14821 ggattttcta aaaaaacgat gtgcacaagc aattgatttt ttaagtcccc aacaactaat
    14881 caatgattta agtaaatctc tttttggcgg tgggtatggt gataaactct ttcctccgac
    14941 gatacaagtc aatccaaatt ttacaggagc tatttcttat caaggattgg attatgtcag
    15001 tttggaaggt gagtttgggc aagattttgc ccagcttgcc tattgggctt ataatattat
    15061 ggtgcaaaaa acactcccta ttgagttgtg gcttgaatat gagaaggaag gcaattgtga
    15121 ctttcgtttg gttatccgta aaatgtggag tgggtctgtt gatgatttct ttgaagaagt
    15181 aatagtatct gaaaaagact tggagcaagc actttttatg gatagtcgag acggagacta
    15241 ctttctctcg atatctgttg aagcaagagg tcgtggaact atcaaactag gtaatcttca
    15301 tcaacgatgg agtcgaaaac aatttggtaa gtttgtactt ggtggaaata tcctacatga
    15361 ttccaagcgt gatgaaataa actatttctt ccatccaggt gattttaaac cgcctttgac
    15421 tgtctatttt gcaggttatc gacctgcaga aggattcgag ggttacttta tgatgaaaac
    15481 tcttggatgt cccttcattt tattttctga tccacgttta gaggggggag ctttttatct
    15541 cggaacggat gagctagagg gaaaagtaaa ggatacgatc actcactatc ttgattattt
    15601 aggctttgat cataaggatt tgattttatc aggtctttct atgggaacgt ttccggctct
    15661 ctattatggt gcttcttttg aaccccatgc catcatagtt ggtaagccct tggctaattt
    15721 aggaactata gctagtcgtg gacgtttgga cgcaccgggt gtctctaact tagcttttga
    15781 ttgtttaatt catcatacag gtgggacaag ttctcaagat atgacggagt tggatcagcg
    15841 tttttggaaa atttttaaac aagcaaattt ttcaaagaca acctttggtt tatcctatat
    15901 gaaagatgaa gaaatggatc cacaagccta tgaacaatta gtgtcttatc tgtgtaatac
    15961 aggtgcgaag attttatcta aaggaactgc tggacgacac aatgatgata cagataccaa
    16021 tatttcttgg tttttgcact tttatagaat ggtcttagag actggttttg gaagggagaa
    16081 aagatgatta ttacacagag acagtctatt tattggggag aagttggtgg gacttatatg
    16141 tatggaacaa ctgtatctta ttaccctgac aaaagtgttc gtctgtataa tcctctattg
    16201 ccatctggtg agattctaaa gacttggttt tctagtgtca attaccaggc tgcacgaacc
    16261 caacctcagc ttcccttatt aaaaagaaag caggagtatc aactatcact ggtttttgat
    16321 tgccagcctg aaaatggagt ttataccaag ataacttttt ttgaccgcta tggtgatatt
    16381 ttagaaaaaa aggtagaaaa agcgaaagat ttcatattta cttatccaga agatagttat
    16441 acttatcaag tttctctttt aagtgctgga tttgagtcct taacttttta tcatttttct
    16501 atcaaggaga tcagaagtgt ttagacgttt aggtcaagat ttccagctta ggaaagtgaa
    16561 aaagatttta aagcagatta atgccctgaa aggcaagatg tcctctcttt cggatcaaga
    16621 attagtagct aaaacagtag agtttcgtca gcgtctttcc gagggagaaa gtctagacga
    16681 tattttggtt gaagcttttg ctgtggtacg tgaagcagat aagcggattt tagggatgtt
    16741 cccctatgat gttcaagtca tgggagctat tgtcatgcac tatggaaatg ttgctgagat
    16801 gaatacgggg gaaggtaaga ccttgacagc taccatgcct gtctatttga acgctttttc
    16861 aggagaagga gtgatggttg tgactcctaa tgagtattta tcaaagcgtg atgccgagga
    16921 aatgggccaa gtttatcgtt ttctaggatt gaccattggt gtaccattta cggaagatcc
    16981 aaagaaggaa atgaaagctg aagaaaagaa gcttatctat gcttcggata tcatctacac
    17041 aaccaatagt aatttaggtt ttgattatct aaatgataac ctagcctcga atgaagaagg
    17101 taagttttta cgaccgttta actatgtgat tattgatgaa attgatgata tcttgcttga
    17161 tagtgcacaa actcctctga ttattgcggg ttctcctcgt gttcagtcta attactatgc
    17221 gatcattgat acacttgtaa caaccttggt cgaaggagag gattatatct ttaaagagga
    17281 gaaagaggag gtttggctca ctactaaggg ggccaagtct gctgagaatt tcctagggat
    17341 tgataattta tacaaggaag agcatgcgtc ttttgctcgt catttggttt atgcgattcg
    17401 agctcataag ctctttacta aagataagga ctatatcatt cgtggaaatg agatggtact
    17461 ggttgataag ggaacagggc gtctaatgga aatgactaaa cttcaaggag gtctccatca
    17521 ggctattgaa gccaaggaac atgtcaaatt atctcctgag acgcgggcta tggcctcgat
    17581 cacctatcag agtcttttta agatgtttaa taagatatct ggtatgacag ggacaggtaa
    17641 ggtcgcggaa aaagagttta ttgaaactta caatatgtct gtagtacgca ttccaaccaa
    17701 tcgtccgaga caacggattg actatccaga taatctatat atcactttac ctgaaaaagt
    17761 gtatgcatcc ttggagtaca tcaagcaata ccatgctaag ggaaatccct tactcgtttt
    17821 tgtaggctca gttgaaatgt ctcaactcta ttcgtctctc ttgtttcgtg aagggattgc
    17881 ccataatgtc ctaaatgcta ataatgcggc gcgtgaggct cagattatct ccgagtcagg
    17941 tcagatgggg gctgtgacag tggctacctc tatggcagga cgtggtacgg atatcaagct
    18001 tggtaaagga gtcgcagagc ttgggggctt gattgttatt gggactgagc ggatggaaag
    18061 tcagcggatc gacctacaaa ttcgtggccg ttctggtcgt cagggagatc ctggtatgag
    18121 taaatttttt gtatccttag aggatgatgt tatcaagaaa tttggtccat cttgggtgca
    18181 taaaaagtac aaagactatc aggttcaaga tatgactcaa ccggaagtat tgaaaggtcg
    18241 taaataccgg aaactagtcg aaaaggctca gcatgccagt gatagtgctg gacgttcagc
    18301 acgtcgtcag actctggagt atgctgaaag tatgaatata caacgggata tagtctataa
    18361 agagagaaat cgtctaatag atggttctcg tgacttagag gatgttgttg tggatatcat
    18421 tgagagatat acagaagagg tagcggctga tcactatgct agtcgtgaat tattgtttca
    18481 ctttattgtg accaatatta gttttcatgt taaagaggtt ccagattata tagatgtaac
    18541 tgacaaaact gcagttcgta gctttatgaa gcaggtgatt gataaagaac tttctgaaaa
    18601 gaaagaatta cttaatcaac atgacttata tgaacagttt ttacgacttt cactgcttaa
    18661 agccattgat gacaactggg tagagcaggt agactatcta caacagctat ccatggctat
    18721 cggtggtcaa tctgctagtc agaaaaatcc aatcgtagag tactatcaag aagcctacgc
    18781 gggctttgaa gctatgaaag aacaaatccg tgcggatatg gtgcgtaatc tcctgatggg
    18841 gctggttgag gtcactccaa aaggtgaaat cgtgactcat tttccataag aggagaaaat
    18901 atgacaattt acaatataaa tttaggaatt ggttgggcta gtagcggtgt tgaatacgct
    18961 caagcctatc gtgctggtgt ttttcggaaa ttaaatctgt cctctaagtt tatctttaca
    19021 gatatgattt tagccgataa tattcagcac ttaacagcca atattggttt tgatgataat
    19081 caggttatct ggctttataa tcatttcaca gatatcaaaa ttgcacctac tagcgtgaca
    19141 gtggatgatg tcttggctta ctttggtggt gaagaaagtc acagagaaaa aaatggcaag
    19201 gttttacgtg tattcttttt tgaccaagat aagtttgtaa cctgttattt ggttgatgag
    19261 aacaaggact tggttcaaca tgccgagtat gtttttaagg gaaacctgat tcggaaggat
    19321 tacttttctt atacgcgtta ttgtagcgag tattttgctc ccaaggacaa tgttgcagtc
    19381 ttataccaac gaacttttta taatgaagac gggactccag tctatgatat cttgatgaat
    19441 caagggaagg aagaagttta tcatttcaag gataagattt tctatggaaa gcaagctttt
    19501 gtgcgtgcct ttatgaaatc tttgaatttg aataagtctg atttggtcat tctcgatagg
    19561 gagacaggca ttggtcaggt tgtgtttgag gaagcacaga cagcacattt agcggtagtt
    19621 gttcatgcgg agcattatag tgaaaatgct acaaatgagg actacatcct ttggaataac
    19681 tattatgact atcagtttac caatgcagat aaggttgact tctttatcgt gtctactgat
    19741 agacaaaatg aagttctaca agagcaattt gccaaatata ctcagcatca gccaaagatt
    19801 gttaccattc ctgtaggcag tattgattcc ttgacagatt caagtcaagg gcgcaaacca
    19861 ttttcattga ttacggcttc acgtcttgcc aaagaaaagc acattgattg gcttgtgaaa
    19921 gctgtgattg aagctcataa ggagttaccg gaactaacct ttgatatcta tggtagtggt
    19981 ggagaagatt ctctgcttag agacattatt gcaaatcatc aggcagagga ctatatccaa
    20041 ctcaaggggc atgcggaact ttcgcagatt tatagccagt atgaggtcta cttaacggct
    20101 tctaccagcg aaggatttgg tctgaccttg atggaagcta ttggttcagg tctacctcta
    20161 attggttttg atgtgcctta tggtaatcag acctttatag aggatgggca aaatggttat
    20221 ttgattccaa gttcatctga ccatgtagaa gaccaaatca agcaagctta tgccgctaag
    20281 atttgtcaat tgtatcaaga aaatcgtttg gaagctatgc gtgcctattc ttaccaaatt
    20341 gcagaaggct tcttgaccaa agaaatttta gaaaagtgga agaaaacagt agaggaggtg
    20401 ctccatgatt gaactttatg atcgttatag tcatgaaagt cgagatttac atgaaagtct
    20461 agtcgctact ggtctttctc aacttggagt ggtcatcgat gcagatggtt ttctgcctga
    20521 tggtctgctt tctcctttta cctattatct aggttacgag gatggaaaac ctctctattt
    20581 taatcaagtt cccgtttcag atttttggga aattttagga gataatcagt ctgcttgtat
    20641 tgaagatgtg acgcaggaga gggctgtcat tcattatgct gatggaatgc aggctcgctt
    20701 ggttaaacag gtagactgga aagacctaga aggtcgagta cgtcaggttg accactataa
    20761 tcgtttcgga acttgttttg ctaaaaccac ttatagcgca gatagcgagc cgattatgac
    20821 agtttaccaa gatgtcaatg gtcaacaagt tttactggaa aaccatgtga cgggtgatat
    20881 cttattgact ttgcctggtc agtccatgcg ttactttgca aataaagttg aatttatcac
    20941 cttctttttg caagatttgg aaatagacac cagtcagctt atctttaata ctctagcgac
    21001 tcctttcttg gtttcctttc attatccaga taaatctggc tcggatgtct tggtatggca
    21061 ggaacctctt tatgatgcca ttccaggtaa tatgcagttg attttggaaa gtgataatgt
    21121 gcgtactaag aagatcatca ttccaaataa gacgacttat gagcgcgctt tagagttaac
    21181 tgacgagaaa taccatgatc agtttgtgca cttgggttat cattaccagt tcaaacgtga
    21241 taatttccta agacgagacg ccttaatctt gaccaattca gatcagattg agcaagtaga
    21301 agcaatcgta gaagccttgc ctgatgttac cttccgtatc gcagcagtga cagagatgtc
    21361 ttctaagctc ttagacatgc tttgctatcc taatgtggcc ctttaccaga atgctagtcc
    21421 acagaagatt caggagctgt atcaactgtc ggatatttac ttggatataa accacagtaa
    21481 tgagttgcta caggcagtgc gtcaggcctt tgagcacaat ctcttgattc ttggctttaa
    21541 tcagacggtg cacaatagac tttatgtcgc tccagaccat ctatttgaaa gtagtgaagt
    21601 tgctgctttg gttgagacca ttaaattggc cctttcagat gttgatcaaa tgcgtcaggc
    21661 acttggcaaa caaggccaac atgcaaatta tgttgacttg gtgagatatc aggaaaccat
    21721 gcaaactgtt ttaggaggct aacatgtcag aggaagattt attttacaaa gacgttgaag
    21781 gccgcatgga agagttgaaa caaaaaccca tcaagaagga aaaagaaacc cgaggggaaa
    21841 agattagtaa gactttttca cttttactgg gtttgatgat tctgattggt ttgctcttta
    21901 ctttgctggg aattttgagg tagatctatg attgacatac taattgtttt agctattatc
    21961 ctatctcttg ctttgattgt attggtaact atacaacccc gtcaaaatca actattttcc
    22021 atggatgcca ctagtaatat tggtaaacca agctactggc agagcaacac cttggtcaag
    22081 gtgctcactt tattggtgag tttggcttta tttgttctac tattaacctt tatggtgatt
    22141 acttataaat aaaagaaaac ttcagatatt caccttttgt ggattggtct gaagttttct
    22201 tttttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa
    22261 cacggttttg aggttgtgga tagaactgac gaagtcagct caaaacacgg ttttgaggtt
    22321 gtggatagaa ctgacgaagt cagtaacata tatacggcaa ggtgaagctg acgtagtttg
    22381 aagagtatta ctgtctatat ttttggtaaa aatcaacttt tacttggatg aaggttttgg
    22441 cttcacgtag gagttgaaga agggtggcgc gggtttcaaa ttcttctctt gtcttgggca
    22501 gactgcggtt ccggaagact tccagataac gttcaatttc atctagcaaa tcagaagcag
    22561 gattggtctg gctcagttga cctgcaattt ttgaaaagag ttgcgctaag atcaggcttt
    22621 cactggcggc aaggtgacaa gtgttaatct gttgggccat gtttctcagg atacgacttt
    22681 gtcgctgtct catctcaaag tagtggatat ggtagtcggt ctggtgaaag aggtggtcag
    22741 agtgatccaa atagaccagt ctgagggctt ctttcaaaag cgtgtctaat tctgctacca
    22801 gctgtgctcg gttgcgtccg tctcctctgg ataaatagta tttgaagcgc tggaggatat
    22861 cttttaactt ttcttccacc agcgtgtggt agtgctggat ttcctcttct cgtgaaggca
    22921 tatagagatt aacaagcaag gcaaatcctg taccaatagc aaagagaagg aattcgttga
    22981 ctaggaggtc tggagaggtt gactcttgaa ccaagagatg gctaaccaaa accgtgcttg
    23041 gtgtgatgcc aatttcccag cccatcttgt aggctaaagg aacgtagaag gccagataga
    23101 ggccgagact ccagatatga aatccgctca agtgaaaagc tagaacaccg atagccagag
    23161 ctagaagcat agaaaaaaga cgattgcgag ccagttttaa agtacttcta cgcgtatcag
    23221 ataggctcaa gagagcgata attccagccg aaactgctga cgaaagattg agaaaataag
    23281 caagcaggca ggcaagacag gtagctaaga tgagcttggt cgtacgttgg ctaatagaca
    23341 taagaatttc ctaataagtt agaataaaag cgtaaaagac aagacatgag caggcttgcc
    23401 ttgatgagtt attttttacg ggttgctgcg tattcggcaa cggcggtaaa gaggacatct
    23461 gtagaagagt taagggctgt ttcacatgag tcttggatga caccaatcac aaaaccaacc
    23521 ccaacaattt gtatggcaat atcgttagaa ataccgaaaa ggctacaagc aactgggata
    23581 agaaggaggg aacctccggc aatacctgaa gcaccacagg ctgagatagc tgctaccaca
    23641 ctgaggacaa aggctgtggc aaagtcaaca ggaattccaa gagtgttaac tgtaacaagg
    23701 gtcaaaaggt taatggtaat cgctactcca gccatattga tagtagaacc gagtgggata
    23761 gaaacagaat aggtatctgg gttgagtcca aggtcatggc agagtttcat attgacagga
    23821 atgttagccg cagaactacg agtgaaaaag gctgtcacac cgctgacacg gaggcagttc
    23881 caaactagag ggtaaggatt gcgtctcata aagaagaagg caatcaaagg gttgaccaca
    23941 ggggcaacaa aaagcatagt cgttactaat agaaccaata aaataccgta gttggcaagg
    24001 cttccgactc ccttgtcaga aatggtttta aaaacaagac caaggattcc aaatggagtc
    24061 agattgatga tccattcgac aagtttagaa gtcacgtcag cgatagtttt tagcaattct
    24121 ttactatttt tactggcttc tctcatagcg attccaaaaa tgactgccca agataagatt
    24181 ccaatatagt tagcagtaag cagggcgttg actgggctgt caaccagttt gagcaagagg
    24241 ttgctgagga cctgcccaat cccatctggt ggtgcaattt cagtattggc actatttagg
    24301 gtaatttcaa tagggacgat gaaacttgct agtacagcta caagagcagc ggcgaaagtc
    24361 cctatcatag gatatacaag aaaacaacag ttttcatatt gctatcttgt cccttttgat
    24421 gttgggaaag ggcattggca acgagggcaa agactaggat aggagcaaca gcttttagac
    24481 ctccaacgaa taaatccccg agtagcccaa tccctgagag attaggaagg gtcagtccta
    24541 ggattcccca taaagcatac caatcaagat acgcttgaca aggcttgcct tattccaagc
    24601 atgaatgatt cttttcataa taatctcctt tttgtgtagt gattatgatt atagtataaa
    24661 tgatagacaa aatcaagaat tttctgtcta ttttttgaat atgtatggag aatgagactg
    24721 atgaaaatat ggtataatga aataaaggag ttttatatgc aaaaatttat tcaggcttat
    24781 attgaaaagc tagatgtgac aaccattatc gagaatattc taaccaaggt catttctctt
    24841 ttactgcttt tgattgtatt ttatattgct aaaaaaatgc ttcataccat ggtgcagaga
    24901 attgtcaaac cttctctaaa aatgtctcgt catgatgtcg gacgccaaaa aaccatctca
    24961 cgtttactag aaaatgtgtt taattatacg ctatatttct ttttactcta ctgcattttg
    25021 tcgattttag gtttgccagt ttctagtttg ctggctggag ctggtattgc tggggtagcg
    25081 attggtatgg gagcccaagg ctttctatct gatgtcatca atggcttttt catcctcttt
    25141 gaacgtcaac tggatgtggg agatgaggtc gttctgacaa atggaccgat tactgtatcg
    25201 ggtaaggttg tcagtgtggg aattcgtacg acacagcttc gtagcgagga gcaagccctt
    25261 cactttgtcc ctaaccgaaa tatcacagtt gttagcaatt tctcacgcac agactagacc
    25321 tgttatttta agtaatttgt ggtacaatag agggagttta ataaggagaa aagatggttt
    25381 tagaaaagca gttgggcaat ggttgtacct ggatagacct agacctagga aagttgaata
    25441 aactagaaga cctttctgaa atttacggtt tggacaagga aaccattgaa tacgcactgg
    25501 atagaaacga gcgcgcccac atggactacc accgtgaaag tgggacggtt acctttatct
    25561 ataatgtcct agacgtaaaa aaggacaagg cctactatga gacttttccc atgaccttta
    25621 tcgtcgagca tcgtcgcctg attaccatta gtaataccaa gaacgcctat gtcattgaac
    25681 agatgactcg ttatctggag aaccatgaca cgctttcgat ttataagttt ctctttgcca
    25741 gtctggaaat catcagcaat gcctactatc ctgtcattga gcagatggac aagagtaggg
    25801 atgaggtcaa tgacctcttg cgccagcgaa ctaccaagaa aaacctcttt gccctgtctg
    25861 atttggagac tggtatggtt tatctgacgg cagctgccaa acaaaatcgg attttgttag
    25921 agcatattca aggtcatgcc ttgtatcgta gttttgatga gattgagaga gaacagtttg
    25981 atgatgccat gattgaggct catcagctgg tatccatgac agacctaatc tctcagattt
    26041 tacagcagct ttcagcctct tacaacaata ttctaaacaa taatctgaat gacaatttga
    26101 caaccttgac tattatttca gtcttgctag ctgttttggc agtcgtgaca ggctttttcg
    26161 gaatgaatgt tcccttacct ttaacagatg agccccatgc ttggctctat attagtttgg
    26221 ctagtgcagg tttgtggatt gttttatcct tgttactaag gaaaattgcg aaaaaaagtt
    26281 aagaaaagga gccagaatgg cgattgaaaa ttatatacca gattttgctg tggaagcagt
    26341 ctatgatctg acagtcccaa gcctgcaggc gcagggaatc aaggctgttt tggtcgattt
    26401 ggataatacc ctcattgctt ggaacaaccc tgatggaacg ccagagatga agcaatggct
    26461 acatgacctt cgggacgcgg gtattggcat tatcgtagtg tcaaataaca ccaaaaaacg
    26521 cgttcaacga gcagttgaga aatttgggat tgattacgtt tactgggcct tgaagccctt
    26581 cacatttggt attgaccgtg ctatgaagga attccactat gacaaaaagg aagtggtcat
    26641 ggttggtgac cagctcatga cagatatacg agcagcccac cgtgcaggga ttcggtcaat
    26701 tttagtcaaa cccttggtcc aacatgactc aatcaaaacg cagattaacc gaactcgtga
    26761 gcgtcgtgtt atgagaaaaa tcactgaaaa gtacggaccg attacatata aaaaaggaat
    26821 ttaactatgg aagaaattct ctgtattggt tgtggagcaa ccattcagac gacagataag
    26881 gctggtcttg gttttacccc ccagtcggca cttgaaaaag gtttggagac tggcgaagtc
    26941 tattgccaac gctgtttccg tctccgccac tacaatgaaa tcacagatgt ccagttgacg
    27001 aacgatgatt tcctcaagct cttgcacgag gtgggagaca gtgatgcctt agtggtcaat
    27061 gtcattgata tctttgattt taatggctct gtcatcccag gtttaccacg tttcgtctcg
    27121 ggcaatgatg tcctcttggt aggaaataaa aaagatatcc tccctaagtc agttaagtct
    27181 ggtaagatta gccagtggct catgaaacgt gcccatgaag aaggtcttcg tccagtcgat
    27241 gtggtcctaa cttcagcaca aaataaacat gccattaagg aagtcattga caagattgaa
    27301 cactaccgta agggccgcga tgtctatgtg gtcggtgtga ccaacgttgg aaaatcaact
    27361 ctaatcaatg ctattatcca agaaatcacg ggtgatcaga atgtcatcac tacttcacgc
    27421 ttcccaggga caaccttgga caaaatagag attccgcttg acgacggatc ttatatttac
    27481 gatacgccgg gaattatcca ccgccaccag atggctcact acttgacggc caaaaacctc
    27541 aagtatgtca gtcctaaaaa ggaaatcaag cctaagacct atcagcttaa tcctgagcaa
    27601 accctatttt taggtggttt gggacgcttt gactttatag caggagaaaa gcaaggattt
    27661 actgctttct ttgataatga actcaaactc catcgtagca agcttgaagg agctagtgct
    27721 ttctacgata agcacctggg aactcttctg acaccaccaa atagcaagga aaaagaagat
    27781 ttcccaaggc tagtccagca tgtctttacc attaaagata agacagacct agtcatctca
    27841 ggcctaggct ggattcgtgt aacaggcata gcaaaagtcg ccgtctgggc accagaaggc
    27901 gtcgccgtcg tcacacgaaa agcaattatt taagcacaga aaggaaaggg ttgtctgaat
    27961 ttgggcgagc aaggcgagcc ccatagagaa tacttttcgc tgtggtgtaa gttggtacaa
    28021 gtgattgtac caactgcgga aaatttgaga ccttaggctc aaattttagt catgaaagtc
    28081 cgaaggactt tgctgacgtc cgtcaccact tcagaaaagt ataaaaagaa actcttttaa
    28141 agaaattatg tcattaacat caaaacaacg tgccttcctc aacagccagg cacacaccct
    28201 caaacctatc atccaaatcg ggaaaaatgg actcaacgac caaatcaaaa ccagcgtccg
    28261 tcaagctctt gatgcgcgtg aattaatcaa ggttactctc ttacaaaaca cagatgaaaa
    28321 catccacgaa gtagctgaaa ttttggaaga agaaatcggt gtggatacag tccaaaaaat
    28381 aggacgcatc ttgattttgt ttaaacaatc tagcaagaaa gaaaatcgca agatttctaa
    28441 gaaagtcaaa gaaatctaag accgaaactc caaataactg tttttataga gaaataaagg
    28501 ggactagcct atgacaatcg aactattgac tccctttacc aaggtagagt tggagccaga
    28561 aatcaaggag aaaaaacgca aacaagttgg gattttaggg gggaatttta accctgttca
    28621 caatgcccat ctcattgttg cggatcaagt acggcaacag ttgggactgg atcaagttct
    28681 gctcatgcct gaataccaac ctcctcacgt tgataaaaag gaaaccatcc ctgaacacca
    28741 tcgtctcaag atgcttgagt tggcaattga gggaattgac ggcctagtca ttgaaaccat
    28801 tgagttggag cgcaagggta tttcctacac ctacgacacc atgaagattt tgacagagaa
    28861 gaatccagat acggattatt actttatcat cggtgccgac atggttgact atctgcctaa
    28921 gtggtaccga attgatgaac tggttgacat ggttcagttt gtgggggttc agcgtccacg
    28981 ctacaaggca gggacttcct atccagttat ctgggtggac gtaccgctca tggatatctc
    29041 gtccagcatg gtgcgtgcct tccttgccca aggtcggaaa cccaactttc tcctacctca
    29101 gcttgtgcta gactatatcg agaaggaggg gctctactga tgtcctatca agactatatc
    29161 aactgctctc gtgaggcctt gttggaaaaa atggcagagc ttctacctga gaaacgtcta
    29221 acccattgtc taggtgtgga gcgtgccgct atggaattag ctcagcgctt tggtgtagat
    29281 gttgagaaag caagtctagc aggtcttctt catgactatg ctaaaaagtt gtcagatcag
    29341 gaatttctag acttgattga ccgttaccag ctagaccctg acctcaaaaa ctggggcaat
    29401 aatgtctggc atggtatggt cggaatttac aaaattcagg aagatttgga tttgcatgat
    29461 tcagaaatcc tgcgagccat tgaagtccat acagtcggtg ctggtcagat gacagaccta
    29521 gataaggttg tctatgtagc agactatatc gagcacaatc gatcctttcc tggagtagat
    29581 gtggcgcgtg agattgcaag tctatcgctc aataaggcgg tggcctacga aacagctcgt
    29641 accgtggagt atctagctca tcagggattc cccatctatc cccaaaccct tgaaacctat
    29701 aacgcctttg tgcactattt gaaagaggac taaatgaaga cggcttttat aatcattgat
    29761 gttcagaatg ttttagtaga aactgggttc cagacaaaaa gtctattgga aaaaatttct
    29821 tatttacaaa accaggctag aagcaagaat attgaaatta tctatgttca acatattgag
    29881 aactctgaag ctcaaacatc agaaggttgg cagttatctg cgcttttaaa tcgaaaacct
    29941 gctgaaaagg tctttcagaa gaagtataac agtattttca aagaaactgg cttaaaagaa
    30001 tacttggata aacaggggat tgaaaaatta gttttatgtg gtatgcagac agaatattgt
    30061 gtggatacct ctgtcaaggt tgcctttgaa tatggctatc agcttattgt tccagaaggt
    30121 gctgtcacaa cctttgatgg ggatgacatt ccagcagaaa cgattaatga attttatgag
    30181 gacatttggg aggagcgctt tgcagatgtc ctagattaca aacatatttt ctaaaaagag
    30241 gattaaatga acgaaaaaga attactagaa ctagtcgtga aagcggctga tgagaaacgt
    30301 gcggaggata tcctcgcact tgatgtacaa gatttgacta gtgtgacgga ctactttgtc
    30361 atcactagct caatgaatag ccgtcagttg gacgctatcg cagctaatat ccgtgaaaaa
    30421 gtagctcaag caggctttaa aggtagccat gtcgaaggcg atgcagctgg aggctgggtc
    30481 ttactggacc tcggtgctgt tgtcgtgcat atcttttcag aagaaatgcg tgcccattat
    30541 aatctagaga agctatggca tgaggcgaat tcagtagata tttcagaagc tcttgcttag
    30601 aagatgaact cagttgtagt caactgggtt tctttgctta ttttagaaaa attgatagaa
    30661 aggtaaaggg ctagtggtgt ttaccatgga gctcttggta tcatgattat ggcgacttat
    30721 gaaacctttg cggcggtcta tgatgcggtc atggacgata gtttatacga caaatggacg
    30781 aatttttctc tgcgtcattt gcctaagacc aaggagagaa agaaactctt ggaattggct
    30841 tgtgggacag gaattcaatc agtgcgcttc tctcaggctg gttttgatgt gactggactt
    30901 gacttgagtg cggatatgtt gaagattgcg gagaagagag caacttcagc caagcaaaag
    30961 attgctttta tagaaggtaa tatgctgaat ttgtccaagg cagggaaata cgattttgtc
    31021 acgtgttatt cggactctat ctgctatatg caggatgagg tggaagtagg ggacgtcttt
    31081 aaggacgtgt acaatgtgct gaatgaagag ggagttttca tctttgacgt gcactcgacc
    31141 taccagacag atgaagtatt ccctggctat tcctaccatg aaaatgcgga agattttgcc
    31201 atgctttggg atacatatga ggacgaagtt cctcactcca tcgtgcatga gctgactttc
    31261 tttatcaagg aggctgacgg ttcctttagt cgccacgatg aagtacatga ggagaggacc
    31321 tatgagatct tgacctatga tatcttgctg gaacaggctg gatttaagtc cttcaaactc
    31381 tatgcagact ttgaggataa ggaaccaaca gaaactagca cccgttggtt ttttgtggcg
    31441 cagaagtagg agaacatcat gaccatcaca ggtattatcg cagagttcaa tccttttcat
    31501 aatggccata aatacctgct ggatcaggca gagggactga aaattgttgc catgtcaggg
    31561 aatttcatgc agcgtggaga gcctgctatt gtggataagt ggacaagggc ccagatggcg
    31621 ctggaaaatg gcgcagactt ggtagtggaa ttgccctttt tagtcagtgt tcaggcagct
    31681 gatttctttg gtcaaggagc tgtggatatc ttggatcgct tgggcattga tagtctagtt
    31741 tttgggacag aggaagttcg agattatcag aaaatcgctg acttatacac agagaaaggt
    31801 actgagatgg agaaatttgt ggaaaatctg cctgattccc tttcctatcc ccagaaaacc
    31861 caagctatgt ggaaggaatt tgctggtctt gatttttcag gtaatacccc caatcatgtt
    31921 cttgctctgg cctatgcaaa ggcggttgca ggacgaaata tcaagctgca tccgattcag
    31981 cgtcaggggg caggttacca ttctgtgaat aaagatgtgg actttgcctc ggcgacagcc
    32041 ctccgtcaac atcagaagga ccaagatttc ttagaacgct ttatgccttc tgttgcccta
    32101 tttgagcagg ccagtaaggt gatctgggaa gactattttc ccttgctccg ctatcaaatc
    32161 ttgtcaaatc ccgacctaac caccatctat caggtcaatc aagaaatggc tgtgcgcatt
    32221 aaagaagcta ttaaaacagc ccagtctgtg gaagaattgg tcgagttagt gactaccaaa
    32281 cgttacacca aggcgcgtgt cagacgccta ttgacctata ttttgatgca ggctagagaa
    32341 agtgacttgc cagaagccat tcatgtcctt ggatttactg aaaaaggtag gcaacatctc
    32401 aagtctttga aaggtcaggt cagtctagtc agccgaattg gcaaagaacc ttgggatgct
    32461 atgactcaaa aggctgacca gatttaccaa ctaggaaagc caagtatagc acaacagaat
    32521 tttggaagag tgccgattag aatagaaaca aactaagtct accgaaaggt ggactttttg
    32581 agatttttta cgaataatac tcttcgaaaa tcaaattcaa atcgcgtcaa cgtcgccttg
    32641 ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta
    32701 taaatagata gaaaagaaaa tcttgtacaa gttcctgaca atttctttct tttcgtgtat
    32761 aatagtggaa aagagctaaa acgaggtatg gttatggaag cagtccttta ctcaacattc
    32821 cgaaatcatt taaaggacta catgaagaag gtaaatgatg aatttgagcc tttgacggtg
    32881 gtcaataaaa atccagatga ggacattgta gtcctttcaa agagtgagtg ggatagtatc
    32941 caagaaaccc tgagaattgc tcaaaataag gaactttctg ataaggtttt gcgaggaatg
    33001 gctcaagttc gtgctggaag tactcaggtc catgttattg aggagtaaga aatgctgctc
    33061 aagtttacag aagatgcctg ggcagattat tgctactggc aaaaccaaga taaaaaaaca
    33121 ctaaaaagaa tcaataaatt aatcaaggat attcaacgcg atccatttac aggaatagga
    33181 aaaccagagc cactcaaata tgattaccaa ggagcctggt cacggcgtat tgatgcagaa
    33241 aatcgcttga tttatatgat ggatggagat agcgtggctt tcttgtcctt taaagatcat
    33301 tactaagtct actgcaaagt aggctttttc tcaagtctct actaaactac tatttctaaa
    33361 caacaagttt attttggtaa atgtgttcca aattccccaa aacatattct attttaggtt
    33421 tgtgaaaatc acttttttat ggtagaatgt aaaagaatgt atgtcattcg gaataacaat
    33481 aaaatgaggt aaaaacatgg aaatcatgtc gcttgcgatt gctgtttttg ccgtcatcat
    33541 tggtttagtc attggatatg tcagcatctc agctaagatg aaatcatctc aggaagctgc
    33601 agagttgatg cttttaaatg ctgaacaaga agcaactaat ttacgtggac aagctgagcg
    33661 tgaagcggat ttacttgtta atgaagccaa acgtgaaagc aagtctctta aaaaagaagc
    33721 actattggag gccaaagaag aagccagaaa ataccgtgaa gaagtggacg ctgaattcaa
    33781 atcagaacgt caagaactca aacaaatcga aagtcgtttg acagagagag ctactagcct
    33841 tgaccgtaag gacgacaatt tgacgagtaa agaacaaaca cttgaacaaa aagaacaaag
    33901 tatttctgat agagcgaaaa accttgatgc gcgtgaagag caattagagg aagtcgaaag
    33961 acaaaaagaa gcagaactag agcgtattgg tgctctgtct caggcagaag cacgagatat
    34021 tatcttggct cagacagagg aaaacttgac cagggagatt gccagtcgca ttcgcgaagc
    34081 tgagcaagag gtcaaggaac gttctgacaa aatggccaag gacatcttgg ttcaagctat
    34141 gcaacgtatc gctggtgaat atgtagcgga gtcaacaaac tcaacggttc atctgccaga
    34201 cgatactatg aagggacgca ttattggtcg tgaaggtcgt aacattcgta cctttgaaag
    34261 tttgacaggg gtcgatgtga ttatcgacga tacaccagaa gtggtgacct tgtcaggatt
    34321 tgatccgatt cgtcgtgaga ttgcccgtat gactatggaa atgttgctca aagatggtcg
    34381 tatacatcca gctcgtatcg aagagttggt tgagaaaaac cgtcaagaga ttgacaataa
    34441 gattcgtgaa tacggtgagg ctgctgccta tgaaattggt gcgccaaacc ttcatccaga
    34501 cttgatgaag attatgggac gtttgcagtt ccgtacttca tatggacaaa atgttttgcg
    34561 ccattcgatt gaggttgcta agttggctgg tatcatggcg agcgaacttg gtgaaaatgc
    34621 ggctcttgcc cgtcgtgctg gattccttca cgatatcggg aaagccattg accatgaggt
    34681 tgaaggtagc cacgttgaaa tcggtatgga attggcccgt aagtacaagg aacccccagt
    34741 tgtggtgaat acgattgcta gtcaccacgg agatgttgaa gctgagagcg tgatagcagt
    34801 tatcgtcgct gcagcagatg ccttgagcgc agcccgtcca ggtgctcgta gtgagtctct
    34861 tgaaagctac atcaagcgtc tccatgattt ggaagaaatt gctaacggct ttgaaggagt
    34921 gcaaactagc tttgcccttc aagcaggacg tgaaattcgt atcatggtca atccaggaaa
    34981 aatcaaggac gacaaagtca caatcttggc tcacaaagtt cgtaagaaaa ttgaaaacaa
    35041 tctcgattat ccaggaaata tcaaggtaac cgtgattcgc gagcttcgtg cagtagatta
    35101 tgctaaataa ataagaaaga gcagttgaaa aattactgct tttttgttac actagataga
    35161 aagactgtaa aggataatct ggctttttgc cattattcta gagaaatgtt atttcacaga
    35221 ttgactaaaa ggagacacaa tggcagaccg aggcttacta atcgtttttt ctggtccttc
    35281 aggggttgga aaaggaacgg ttagaagaga gatttttgag agttctgaaa accaatttca
    35341 atattctgta tcgatgacga cacgcgcaca acgtcctgga gaagtggacg gtgttgacta
    35401 cttcttccgt actcgtgaag aatttgaaga gctgattcgt caaggacaga tgttggaata
    35461 cgcagaatat gtcggcaact actatggaac tcctctgacc tatgtcaatg aaaccttgga
    35521 caagggaatc gatgttttcc ttgaaattga agttcagggt gctcttcagg tcaagaaaaa
    35581 ggttccagat gctgtcttta tcttcctgac accaccagat ttggatgaat tgcaagatcg
    35641 cttggtaggt cgtggaacag atagtgcaga agtgattgcc caacgaatcg aaaaggccaa
    35701 ggaagaaatt gccctcatgc gtgagtatga ttatgcgatt gtcaacgatc aggtgcccct
    35761 agctgctgaa cgtgtcaaat gtgtgattga agcagaacac ttctgtgtgg atcgtgtcat
    35821 tggtcactat caggagatgt taccaaaatc tccaactacc cgataaaatt tagaaaatag
    35881 gtacaagcaa atgatgttaa aaccctctat tgataccttg ctcgacaagg ttccttcaaa
    35941 atattcactc gtaatcttgg aagcaaaacg tgcccacgaa ttggaagcag gtgccccagc
    36001 aactcaaggt ttcaagtctg aaaaatcaac tcttcgcgct ttagaagaaa tcgaatcagg
    36061 aaacgttaca attcacccag atccagaagg aaaacgtgaa gcagtgcgtc gccgtatcga
    36121 agaagaaaaa cgccgcaaag aagaagaaga aaagaaaatc aaagagcaaa ttgctaaaga
    36181 aaaagaagat ggtgaaaaaa tttaaggttg gggggactca atcttatttt ttctattgca
    36241 agaatgtact gacaaggagg aggtgagaag atggccctag ctaagattat cgtagatgtg
    36301 cccttgatgc agacggacca gccctatagt tacaggattc cggaggaatt tgagggaatg
    36361 ctggaagttg ggatgcgggt tcatgtgcct tttggtaagg gtaatcgcct gattcaaggg
    36421 attgtttttg gtttggagtc ccaatcagat ggagaagaga tggagcaaga tttaaaagat
    36481 attgcagagg tgctggattt ttctcctgtt ctcacgccag aacaactctg gctggctgag
    36541 gagttacgca aatctgtctt ctcctacaaa atctctatcc tcaaggccat gcttccggga
    36601 tttctgaatt ctagctatga caagattctc tatcctctgg aaggcttgag tcaggaagaa
    36661 cgagtgcgcc tgtttggttc agaagattcg ctagcctttt cttctctgga tttaggtaag
    36721 caagctgaaa tgatgcgttt gactagaaaa ggcctgcttg gtctggaata tcaggcagtc
    36781 gatcaaaaga aggtcaagac ccagtcttgg tatgaggttg accatgctca attagaaggt
    36841 gttgagattt ctacacgtgc caagaaaaag ttggaactga gagattatct gctgtctcat
    36901 ccagagagcg cttccttggc tagcttgtta gagtcctact cgcgagagca agtcaacttc
    36961 tttgtggatc aaggtgctgt taccatagtc caaaaggaag ttcgacgctc ggctgcttat
    37021 tttgaaggaa ttgaagcaag tagacctttg gagttaaatc cagaacaaag acaggcgcgt
    37081 gatgcggttg tgagttctat tggcagttct caacctccct ttctacttca agggattaca
    37141 ggaagtggga agaccgaggt ttacttgcag attatccaag gtgccctgga taagggcaag
    37201 acagctattt tgctggtacc tgagatttcc ttgactcctc agatgaccga gcgttttata
    37261 gcacgttttg gggacaaggt agccattctt cactcaggat tatccaatgg cgaaaagtat
    37321 gatgaatggc gcaaggtgga gcgtggcgat gcccaagttg ttgttggtgc cagatctgct
    37381 atctttgctc ctctgaaaaa tctgggtgtc atgattattg atgaagagca tgaagcggct
    37441 tataagcagg acagcaatcc ccgttaccat gccagagagg tagctatttt acgggctcag
    37501 tataatcaag caactctggt acttggatct gcaacgccga gcttagagag ccgggcacgt
    37561 gctggcaaag gcgtctatca acacttacgt ctaacccaac gtgccaatcc tttggctaca
    37621 atccctgagg ttcaagtgat tgactttcga gactatatcg gacaaaatga gacgtcaaac
    37681 tttacgcctc ctttgctaga ggctatccaa gaccgtctgg ttaaaaaaga gcaggtggtt
    37741 ctcatgctca atcgccgtgg ttattctagc tttgtcatgt gtcgggagtg tgggacggtg
    37801 gatacttgtc ccaactgcga tatttctctg accttgcata tggataccaa gactatgaac
    37861 tgccattatt gtggtttctc gaaggatatt cctcaggtct gtcctaactg taagagccac
    37921 agtattcgtt actatgggac gggaactcag aaggcttatg atgagctagc agaactcttt
    37981 ccccaagctc gcattttgag gatggatgtg gatacgactc gaaagaaagg cagtcaccaa
    38041 gccttgcttg accagtttgg gcgaggggaa gcggatattt tacttggtac tcagatgatt
    38101 gcaaagggtt tggattttcc caatgttacc ctagtcggag ttctaaatgc ggatacggcc
    38161 ttgaatctgc ctgatttccg ttcttctgag agaaccttcc agctcttgac tcaggtggca
    38221 ggtcgagcag gtcgggctga aaaagcaggt caagtcttga tacagtccta caattcgcag
    38281 cactatgcta ttcgatttgc caaggatcaa gattacgaag gcttttatgc ctatgaaatg
    38341 ggaatcagac gacaactcgg ctatccacct tactatttca cgattggtat taccctttct
    38401 cacaagaaag aagaagaggt tttcaaacgt gcctatgaag tcatgaacat tttgcggtca
    38461 ggcttgtcag agaccagtcc cattctgggg ccaacgccaa aaccgattgc ccgtacccac
    38521 aacctctatc attaccagat tttaattaaa taccgtttag aggatgagct ggggccgacc
    38581 ctcaaccagg ttttagcctt gactcaagaa cgggaaaata gtgagctccg tctcagcatt
    38641 gaccatgagc cgcaacaatt tttataagaa ggagaagata tgacaaaact aatctttatg
    38701 gggacccccg acttttcagc aacagtctta aaaggacttt tgacagataa ccgttacgaa
    38761 attctagccg ttgcgaccca gccagaccgt gctgttggtc gtaaaaaagt tatccaagaa
    38821 accccagtca agcaggctgc caaggaagca ggactatcta tctaccaacc tgaaaaatta
    38881 tctggaagtc cagagatgga agatcttatg aagctaggag cagatggaat tgtgactgct
    38941 gcttttgggc agtttctccc aagcaaactc cttgatagca tggactttgc tgtcaacgtt
    39001 catgcctccc tccttcctag acaccgtggt ggtgcgccta tccattatgc cttgattcaa
    39061 ggggatgagg aagctggtgt gaccatcatg gaaatggtta aggaaatgga tgcaggagat
    39121 atgatttctc gtcgcagcat tccgatcaca gatgaggaca atgttggcac cttgtttgaa
    39181 aaattggcgc tagttggtcg tgatttgctt ttggacactc tgcctgccta tattgctggt
    39241 gatatcaaac ctgaaccgca ggatacgagt caggttacct tctctccaaa tataaagcca
    39301 gaggaagaaa aactggactg gaacaaaacc aatcgtcaac tctttaacca aattcgtgga
    39361 atgaacccct ggcctgttgc ccatactttc cttaagggcg accgctttaa gatttatgaa
    39421 gccctaccag tagaaggtca gggaaatcca ggtgagattc tctctatctg caagaaagaa
    39481 ttgattgtcg caacggctga aggggctcta tccctcaaac aagtgcagcc agctggtaag
    39541 cctaagatgg acattgcttc cttcctcaac ggagttggac gtacattgac tgtaggagaa
    39601 cgatttggtg actaaagtag aaacggctag aagtttagct ctagcagtgc tagaggatgt
    39661 ttttgtgaat caagcatatt caaatattgc cttaaataaa cacctcaagg ggagtcagct
    39721 ctctgcagca gacaagggct tagtgaccga gctagtctat ggaacggtag cccgtaaact
    39781 gactctggaa tggtacctat cccactttat cgaagacaga gaccagttag acagctggct
    39841 ctatgtcctt cttctcatga gtgcctacca actccgctat ttggacaaga ttccagatca
    39901 tgctgtggtc aatgaagcag tggaattagc caaactccgt aaaaaaggca gtgaaaaatt
    39961 ggtcaacgct gtccttcgcc gtatcttgcg tgaaggctgg ccagatattg ctagcatcaa
    40021 gcgaaaaaac aagcgtgact ccattgccta ttctctccca gtttggctag ttgccaaact
    40081 caaggaagaa tacggagagg agagagcaaa agccatcttt gaaagcctgt tagtgcgaaa
    40141 caaagccagt attcgtgtaa cagacctaag tcgaaaagag gaaatccaag ccttgttgga
    40201 ggcgaatgat tcccttttag caaccactgg tctggttaag gagcaagggc attttgcagg
    40261 gcataatttg tttgcggatg gagccattac catccaagac gagtccagtc agctggttgc
    40321 tccgacgctt gatttacaag gtgatgagcg agtgcttgat gcctgtgcgg ctccaggtgg
    40381 gaaaacagcc catatagcct cttatcttac gacaggtcag gttactgctc tggacttgta
    40441 cgaccacaag ttggatttaa ttcaagaaaa tgcccaacgt ctgggaattg aagatcgggt
    40501 tcaaactcaa aaattagatg ccagaaaggt gcatgagttt tttgaccagg attcctttga
    40561 taagattttg gtggatgctc cttgttcagg aatcggtctt ttgcgccgaa aaccagatat
    40621 caaatacaat aaagaaacgg cagatttcgc gtccttgcag gaaattcagt tagaaatatt
    40681 aggtagtgtt tgtcaaatac taggcaaagg tggtataata acttatagca cctgcactat
    40741 cgtctcagag gagaattttc aagtcgttaa ggccttttta gagagtcatc ccgagttcga
    40801 gcaggtaaaa ctagaacatg aatgtaagga tatcatgaaa gacggctgta tcctcattac
    40861 acctgaattg tatggaagtg atggattctt catcagtcaa tttcgcaaga tatcggatta
    40921 ggaaggaact gacacatgga aatttcatta ttaacagatg ttggtcagaa acgaacaaat
    40981 aaccaagact atgtcaacca ctatgtcaat agagctggac gtaccatgat tattttagct
    41041 gatgggatgg gaggtcatcg cgcagggaat atcgctagtg aaatggcggt cacagacctg
    41101 ggtgtagctt gggttgatac ccagatcgat acagtcaatg aagtgcgtga atggttcgcc
    41161 cattacctag aaattgaaaa tcaaaagatt caccagcttg gtcaggatga agcttacaga
    41221 ggcatgggaa ctactttgga agtccttgct attattgata atcaggctat ctatgctcat
    41281 attggtgatt cgcgtatcgg cttgattcgt ggagaagaat accatcagtt gacgagcgat
    41341 cattccttgg ttaatgaatt gctcaaggct ggtcaattga caccagaaga ggcagaagct
    41401 catccgcaaa aaaatattat cacccagtct attgggcaaa aagatgaaat tcagcctgat
    41461 tttaggacag ttatccttga gtcaggtgac tatctcttgc tcaatagtga cggcttgacc
    41521 aacatgattt caggcagtga gattcgtgat attgtaacca gtgatattcc tttagcagat
    41581 aaaacggaga cacttgttcg ttttgctaac aatgcaggag gtttagacaa cattacggtt
    41641 gcccttgttt ctatgaacga ggaggatgca gaatgatcca aatcggcaag atttttgccg
    41701 gacgctatcg gattgtcaaa cagattggtc gaggaggtat ggcggatgtc tacctagcca
    41761 aagacttaat cttagatggg gaagaagtgg cagtgaaggt tctgaggacc aactaccaga
    41821 cggacccgat agctgtagct cgttttcagc gtgaagcgag agctatggca gatctagacc
    41881 atcctcatat cgttcggata acagatattg gtgaggaaga cggtcaacag tatcttgcaa
    41941 tggagtatgt tgctggacta gacctcaaac gctatatcaa ggaacattat cctctttcta
    42001 atgaagaagc agtccgtatc atgggacaaa ttctcttggc tatgcgcttg gcccatactc
    42061 gaggaattgt tcacagggac ttgaaacctc aaaatatcct tttgacacca gatgggactg
    42121 ccaaggtcac agactttggg attgctgtag cctttgcaga gacaagtctg acccagacta
    42181 actcgatgtt gggctcagtt cattacttgt caccagagca ggcgcgtggt tcgaaggcga
    42241 ctgtgcagag tgatatctat gccatgggga ttattttcta tgagatgttg acaggccata
    42301 tcccttatga cggggatagc gcggtgacca ttgccctcca gcatttccag aaacccctgc
    42361 cgtccgttat tgcagaaaat ccatctgtac ctcaggcttt agaaaatgtt attatcaagg
    42421 caactgctaa aaagttgacc aatcgctacc gctcggtttc agagatgtat gtggacttgt
    42481 ctagtagctt gtcctacaat cgtagaaatg aaagtaagtt aatctttgat gaaacgagca
    42541 aggcagatac caagaccttg ccgaaggttt ctcagagtac cttgacatct attcctaagg
    42601 ttcaagcgca gacagaacac aaatcaatca aaaacccaag ccaggctgtg acagaggaaa
    42661 cttaccaacc acaagcaccg aaaaaacata gatttaagat gcgttacctg attttgttgg
    42721 ccagccttgt attggtggca gcttctctta tttggatact atccagaact cctgcaacca
    42781 ttgccattcc agatgtggca ggtcagacag ttgcagaggc caaggcaacg ctcaaaaaag
    42841 ccaattttga gattggtgag gagaagacag aggctagtga aaaggtggaa gaagggcgga
    42901 ttatccgtac agatcctggc gctggaactg gtcgaaaaga aggaacgaaa atcaatttgg
    42961 ttgtctcatc aggcaagcaa tctttccaaa ttagtaatta tgtcggtcgg aaatcctctg
    43021 atgtcattgc ggaattaaaa gagaaaaaag ttccagataa tttgattaaa attgaggaag
    43081 aagagtcgaa tgagagtgag gctggaacgg tcctgaagca aagtctacca gaaggtacga
    43141 cctatgactt gagcaaggca actcaaattg ttttgacagt agctaaaaaa gctacgacga
    43201 ttcaattagg gaactatatt ggacggaact ctacagaagt aatctcagaa ctcaagcaga
    43261 agaaggttcc tgagaatttg attaagatag aggaagaaga gtccagcgaa agcgaaccag
    43321 gaacgattat gaaacaaagt ccaggtgccg gaacgactta tgatgtgagt aaacctactc
    43381 aaattgtctt gacagtagct aaaaaagtta caagtgttgc catgccgagt tacattggtt
    43441 ccagcttgga gtttactaag aacaatttga ttcaaattgt tgggattaag gaagctaata
    43501 tagaagttgt agaagtgacg acagcgcctg caggtagtgc agaaggcatg gttgttgaac
    43561 aaagtcctag agcaggtgaa aaggtagacc tcaataagac tagagtcaag atttcaatct
    43621 acaaacctaa aacaacttca gctactcctt aaaagcagat ggataatcaa aatgagtaat
    43681 caatctttgt catgatttca tggcaaagat tttttttgag tccagatttg tgatagaata
    43741 gagggagttg ataaaaggag gaaagcatgg aagaatcaaa agaattaaat gccgtcattg
    43801 atgtgattat gctagcgggg actattctcc ttaaaagtgg ctcagaaatc catcgtgtag
    43861 aagataccat gattcgaatc gcgcattcgc aggggattgt ggattgcaat gtccttgcca
    43921 tgcctgccgc tatctttttc tctattgaaa ataccaatat ttcgcgcatg aagcgcgtga
    43981 cctcctcttc ttataacatc gaaaaagtct gcgatgtgaa ccagatttct cgtcagctag
    44041 ttggggggca gattgactta gaaacagcct ttaagcaatt gacggccttg caagctcaac
    44101 cccttcccta tactaagttg caggtaactc tggctgcgac ctttagtgct cctttctttt
    44161 cagttatgtt tagcggaaat atctacgacg cacttggggc aggagtggcg accttatttg
    44221 gttttgcctt ttccctctat gtggaaaaat ttatccgaat tccctttgtg acagcctttg
    44281 ctggagcctt tgtctttggg ataattgccc agttttgggc tcgctacaca ggttttcctt
    44341 caacggcaga tttgattata gctggtgcgg tcatgccgtt tgtaccaggt attgccttga
    44401 ccaatgcggt ccgtgatatt atgaccaacc acataaactc tggtatgagt aagatgtttg
    44461 aatccctgct cattaccctc gctttagggg caggaacttc tgtcgccttg gtattgatga
    44521 actaatatga cactaacaac ctttttatta caagcagtag caagttttct tgccattatc
    44581 acttttttaa tcgtactcaa tgtgcaacgg tctatgctct tacctggagg gattttgggc
    44641 atgactgtct ggctaatcta tctcttgctc aaggaaccga ccaatgtcat tgtagctacc
    44701 ttcattgcag ccattattgg ttcttgtgtc agccagattt taagtattct ttataagaca
    44761 cctgctgtgg tctttatctt ggccattttg gcaccgctgg ttccaggtta tctctcctac
    44821 cgaacaactg ccttttttgt gacaggggac tataataaag cactggcaag tgcgaccttg
    44881 gttgtcatgt tggctttggt aatctctatt ggaatggcta gcggaacagt gattctcaga
    44941 ctgtatcatt atataaaaac acatcgagta tcgtagactt tacagaaata aaagaatttt
    45001 ctgaaaaatg agataaataa attgacaacg ctttctatat gtgcgagaat accgcactta
    45061 tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac ttaatccgtc ggagccaatg
    45121 ggttgaagta actcttgttc aaagtggtgt tacgatttca aaaactcatc ttagtgctga
    45181 gaatacggtg attgtggatg caacagaggt aaaaataaat cgtcctaaaa aaatcaacta
    45241 gccaattatt ctggtaaaat agaaatgtca ttctatggaa cctcaagcga ttgtcacaag
    45301 tcaagggaga attgtttctt tggatatcgc tgtgaactat tgtcatgata tgaagttgtt
    45361 caaaatgagt cgcagaaata tcggacaagc tggaaaaatc ttggctgaca gtggttatca
    45421 aggacccatg aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc
    45481 gctaatagct gaagataaag cttataacca tgcgctatcc aaggatagaa gcaaggttga
    45541 gaacatcttt gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg
    45601 taaacgcttc ggattacgaa tgaatttgat tgctggcatt atcaattatg aactaggatt
    45661 ctagttttgc aggaagtcta ctattttcct tattgtctgt aagtctactg accttgttgt
    45721 ttatcccagt catggtttct agttcgggct cagagtttca aagtggatgg caagagcatc
    45781 aattgattgc tgagaaggtt agtaaaacac ttgacaagac atttgataag gatgtcagag
    45841 aaattccgac cagtcagttt tatcaaaaat ttgtagatga gatgggaagg acttactcag
    45901 gaaatttgat cctccaggag ctgataactg tgaatggagc ttataaagct acttatatcg
    45961 gtgaactctc tagcaactaa tcattcttta aaatgatgac caataagagg cttgatttgg
    46021 tgaatcaagt cttttttctc tcttttactg ccatttgtga taaaatagta tagaacgatt
    46081 ttttacatga atgataaaac agaggtaaat atgacaatcg gtattgataa gattggtttt
    46141 gcgaccagtc aatatgtctt gaaattacaa gacttagcag aagcgagggg aattgaccct
    46201 gaaaaattaa gtaaaggact cttactcaag gaattgagta ttgcgcccct aactgaggat
    46261 atcgtgacct tggcggccag tgctagtgac tctattttaa ctgagcaaga aagacaagaa
    46321 gttgacatgg tcattgtggc gaccgagtca ggaattgacc agagtaaggc tgcggccgtc
    46381 tttgtgcatg gcttgctggg catccagccc tttgctcgta gtttcgagat taaagaagcc
    46441 tgttatgggg cgacagctgc cctccattat gccaaattgc atgtggaaaa ttctccggag
    46501 tccaaggtat tggtcattgc cagtgatatt gccaaatatg gtattgaaac tccgggagaa
    46561 ccaactcaag gtgctggaag tgtagctatg ttgattacac aaaatccacg catgatggcc
    46621 tttaataatg acaatgtagc tcagacccgt gacatcatgg atttctggcg accaaattac
    46681 tcgacaactc cttatgtaaa tggtgtttat tctacccaac aatacttgga tagtttgaaa
    46741 acgacttggc ttgaatatca aaaacgctac cagcttactt tggatgattt tgctgctgtt
    46801 tgtttccact tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat catggataag
    46861 agcctgcctc aagagaaaaa agacctctta caaaagcatt ttgaccagtc tattctctac
    46921 agtcaaaagg tggggaacat ctacacaggt tcacttttcc ttggactttt gtctctcttg
    46981 gaaaatacag atagcttgaa agctggggat aaaatcgccc tttatagtta cggaagtgga
    47041 gctgtggctg agttcttcag tggtgaattg gttgaaggat atgaagctta tttggataaa
    47101 gaccgtttga acaagctcaa ccaacgaact gccctatccg ttgcagacta tgaaaaggtc
    47161 ttttttgagg aagtaaactt ggatgaaaca aactctgccc agtttgctgg ctatgaaaat
    47221 caagattttg ccttggttga aattcttgac caccaacgcc gttatagcaa ggttgaaaaa
    47281 taatgaagat aagttggaat ggattttcta aaaaatcata ccaagagcgc ctcgagctgt
    47341 taaaagctca ggcgctcctt agtcctgaga gacaagctag tctggagaag gatgaacaga
    47401 tgagtgtgac tgtggcagac cagctgagtg agaatgtggt gggaactttt tctctgcctt
    47461 attcgctggt tccggaggta cttgtcaacg atcaggaata caccgttccc tatgtgacag
    47521 aagaaccctc tgtggttgcg gcggccagct atgccatcaa aatcatcaag cgtacaggtg
    47581 gttttactgc acaagtccat cagcgacaga tgattgggca ggtagccctt tatcaagttg
    47641 ctaatcctaa actagcgcaa gagaagattg ccagcaagaa agcggagctc ttggagcttg
    47701 ccaatcaagc ctatccttct atcgttaaac gtggaggtgg ggcgcgtgat ctgcatgtcg
    47761 agcagataaa aggcgaacca gactttctcg ttgtttatat tcatgtcgat acccaggaag
    47821 ccatgggtgc caatatgctc aacaccatgc tggaagcctt gaaaccagtc ttagaagaac
    47881 tcagtcaggg acagagtctc atgggaatcc tgtccaacta cgcgactgat tctctggtga
    47941 ctgcaagctg tcgcatcgcc tttcgctact tgagccgcca aaaggatcaa ggacgagaga
    48001 ttgcggagaa aattgcgttg gctagtcagt ttgcgcaggc tgatccttac cgagctgcta
    48061 ctcataataa aggaattttt aatggtattg atgcgatttt gattgccact ggtaatgact
    48121 ggcgtgccat cgaagctggg gcccatgcct ttgccagtcg agatggacgc tatcaaggtc
    48181 ttagctgctg gacgctggac cttgaaagag aagaattggt cggtgagatg accctgccca
    48241 tgcctgtagc gactaagggt ggctctatcg gcctcaaccc acgtgtagct ctcagtcatg
    48301 atctactagg aaatccttct gccagagaat tagcccagat tatcgtgtcc atcggtcttg
    48361 ctcaaaattt tgcagccctc aaagccttgg taagtacggg catccagcaa ggccacatga
    48421 aactacaggc caaatctcta gctctcctag ctggggctag tgaatctgaa gttgctcccc
    48481 tagtagagcg cctcatctca gataaaacct ttaacctaga gacagcccag cgctatctcg
    48541 aaaatttaag atcataaaaa ctcagacgaa tcggtctgag ttttcttgtg tttaaatact
    48601 ttttcctggt aatagcgtaa ctggtaagaa gtaaccagtt gtggcgactt ccttgccttc
    48661 aatcttttgc aagagaagat caatagtgag acaagcaatc tcttccaaag gttgcttgat
    48721 agtagccaat tgagggtagt aattttcgat aaagtaggtc ccatcatagc cgatgacctt
    48781 gagctctttt gggacagaaa tgcccaattc ttgagcgatt ttaatgacca gaatagctgt
    48841 caaatcatcc gaagcaaaaa tggcatctgg tttttcccgg gtcaagatat tcttgatttc
    48901 catttctttt ctgacgggag aaaagtcact ggaaacattg ataataggag cttttgggag
    48961 tacggatgca aaaccagcgt ggcgcagtcc ggttggcgaa ttagaattgt cattccctgt
    49021 aatcatgatg atagactggg cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc
    49081 agcatagttg tcagaggaga cgacagggat gtctggcgat aggtttcggt caaaggaaat
    49141 aatcggcgct gtcacacgat tgtagtcttc gattcctagg ttgtgactac cagaaatgat
    49201 gccgtccacc tgattggctt ccaacatttc gatgtattcg cgttccttct cagaatcatg
    49261 ttcactgttg cagatgatgg tcttgtaacc atttttgaag agttggtgtt ccaatttatc
    49321 aatcaattct gcatagaaaa cattggaaat attggggaaa atcaagccga ttaacttagc
    49381 tgattttcct tgcagactac gagccaggtt gttgggttta tagcccaatt ctctcatggc
    49441 ttcattgact ttttggatgg ttttctcaga tagataccct tttttattga taacccgaga
    49501 aacggtagta ggactgacgc ctgcaagttt ggcgacatca gttagttttg cgaccataat
    49561 ctaattcata gtaagttcca gttgggtttc cagatttgat caggatacca ttttggtccg
    49621 catgtgggaa gacacgacca gaaaatactt tttctccttt attgatgaaa atttcaaaga
    49681 cagagttatc gatgaagatt gtagcagtag tagcctgatt ctcgataggg caagaacgag
    49741 ttgtcccaaa ttcttgggca tactgctctc cagcctggct acgatccact gtcacttgac
    49801 cgtttacaag gtcaaagttg attgaaagtc ccttaccttc tttatcagca agtaagacaa
    49861 tctcgctctg gctattagct tccaagttga gttcaagttc gtaagtgttc ttggtttggg
    49921 aacggtttga gaaggcttct tcagaagcac gaaggtcctt aatagcagcg actggatact
    49981 ggtagagctt gtcgtctttg atagtgagtt ccttgaccaa agagaaggtt ccttggtggt
    50041 caaaacggtc agatgggtaa gaaacatctg gcaaaccaag ccagctaact gctagagcac
    50101 gcccatcagg agcgttgaag gcttgagttg cataggcttc gaaaccgtaa tccatgtttt
    50161 gaagttgaga cacatctacc attttggcat ttttagggtc aaaggaagcc ccaatcttat
    50221 acatatttgg aaagatatta tcgtagtcta gaactttctt atccaatcct tgtggacagt
    50281 agagaaggac aggatgttcc tctacaaaga ccagattagg acattccatc atgtaggcag
    50341 tacggtcgtt agcaaagtca aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga
    50401 cagccttgta gagacggacg aagccttttt tctccaagtc ctgtccaccg acgacagcat
    50461 agtattgacc tttaaagtta aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg
    50521 gctggtcaat caagatcttg tcaatctttg taatcttacc ctccttgtcc atcaaagcac
    50581 cgatctggta tgggtgacgg atccagtttt catcgcgaac atttcctgta taaaatagga
    50641 ataagttatc gccaaattgc atggcagaac cagagtaggc accgtggcta tctaatggag
    50701 tatctggtaa aactttgatt ccagtttctt taaagtgaac caaatcatca ctttctagct
    50761 gtgcccaaga tttcaaaccg tgggctgcac caaaaggaaa attctggtaa aagaggatcc
    50821 acttgccatc aaagtaagaa aagccatttg ggtcgttgag aagtcctgtt tttggctcaa
    50881 catggtaatg agtatgccat ggagattgtg ccatattttc ctttatatgt tgaatttctt
    50941 cttgcgtcca atcttgataa agtctgtaac gacgctcagt tgtccattcc attcattcct
    51001 ccaaaaatct tatcactttt aatagtaact gttttcgata aaaaatgcaa gccttttata
    51061 ttaaaaaaga gaaaaaactg tcaaacgatt accataaaat aaatacagga aatcaatcaa
    51121 atttttacga aaatgtgaaa gataatgaaa taaaagactt tttaaccaag gtttcaaact
    51181 tatttttcaa gaaattcctg atgaaacagt caaaaacaat caatctaaag cttgcccact
    51241 aagtagatag aatatttttt ctgcaaaacg cttgacatat ttttaaaaca tgataaaata
    51301 atagtcgtaa gggcgaataa aatcgctttc aaacaagaac aaaatgttat ataaggagat
    51361 ttttgcaaat gaacaatcag gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg
    51421 aaaatgtcaa tagtgttgcc cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag
    51481 agaaaatcaa taaagaagtg attgagaact tggaaaaagt tcaaggtgct ttctttaact
    51541 cagggcaata ccaaattatc tttggtacag gtacagttaa caaaatgtac gatgaagttg
    51601 ttgtacttgg cttaccaaca tcatctaagg atgacatgaa agcagaagtt gctaaacaag
    51661 ggaactggtt ccaacgtgct atccgtactt tcggtgatgt tttcgttcca atcatcccag
    51721 ttatcgtagc gacaggtctc ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc
    51781 cacttccagg tgactttgca acttacacac aaatcttgac agatacagcc ttcatcatct
    51841 tgccaggttt ggttgtgtgg tcaaccttcc gtgtatttgg tggaaatcct gccgttggta
    51901 tcgttcttgg tatgatgctt gtctctggct cacttccaaa cgcttgggca gttgctcaag
    51961 gtggtgaagt aacagcgatg aacttctttg gtttcatccc tgttgttggt ttgcaaggtt
    52021 ccgttcttcc agccttcatc atcggggttg tcggagctaa atttgaaaaa gctgtccgca
    52081 aggttgttcc agatgtcatt gacctcttgg taacaccatt cgtgacactt ttggtcatgt
    52141 ctatccttgg actctttgtc attggaccag ttttccacgt tgttgaaaac tacatcctta
    52201 ttgctacaaa agcgattctt agcattccat ttggtcttgg tggtttcttg attggtgggg
    52261 ttcaccaatt gatcgtcgtg tcaggtgtgc accacatctt caacttgctt gaagtgcaat
    52321 tacttgctgc tgaccatgct aacccattca acgctatcat cacagctgct atgacagctc
    52381 aaggtgctgc tactgttgcg gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg
    52441 ctttcccggc tgctctttct gccttcctag gtattacaga gcctgctatc ttcggggtga
    52501 acttgcgctt ccgtaaacca ttcttccttt cattgattgc tggtgcaatc ggtggtggat
    52561 tggcttctat ccttggactt gctggtactg gtaatggtat caccatcatc cctggtacaa
    52621 tgctttatgt tggtaacgga caacttccac aataccttct tatggtagct gtatcatttg
    52681 cccttggttt tgctcttact tacatgtttg gttacgaaga tgaagtagac gcaactgcag
    52741 ctgcaaaaca agctgaagtg gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa
    52801 atgaaacact tgtaactcct atcgttggtg atgttgtcgc tcttgctgat gtcaatgacc
    52861 cagtcttctc aagtggagct atgggacaag gtatcgctgt gaaaccaagc caaggcgtgg
    52921 tctatgcacc agctgatgct gaagtttcaa ttgcctttcc aacagggcac gcttttggtt
    52981 tgaaaacaag aaatggtgct gaagttttga ttcacgttgg tattgacact gtatctatga
    53041 acggtgacgg ttttgaagca aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc
    53101 ttggaacatt tgactcaaac aaaatcgctg cagctggact tgatgataca acaatggtta
    53161 tcgttacaaa tacagctgac tacgcttcag tagctccagt cgcaacaggt tcagttgcga
    53221 agggggatgc tgtgatcgaa gtgaaaatct aatcaatcct ctctaataaa aacgaacaaa
    53281 tgacatgttt gttcgttttt attagatagt aagatttaca gaggaaaatc taaaaaatag
    53341 agacatttag actttcgaag tatgctataa taaagaaaat aaaaacaaga ggtttatcat
    53401 gacaaaatta tatggaagct tggaagcggg cggtacaaag tttgtctgtg ctgtcggtga
    53461 tgaaaacttt aacgttgtag aaaaaacaca atttccaaca acaactccaa tcgaaacaat
    53521 cgataaaacc attgagttct tctcaaaatt cgataacctt gctggtcttg cagttggttc
    53581 atttgggccg attgatattg acaaaaactc aaaaacttat ggctttatca cgacgactcc
    53641 aaaaccaaac tgggcaaatg tggacttgct tggtgccctt cgtcgcgccc taaacgtgcc
    53701 aatgtacttc acaacagacg taaacagctc tgcttacggt gaagtggttg cccgtaacaa
    53761 tgctggtggt cgtatcgaaa acttggttta ctacacaatc ggtacaggta tcggtgcggg
    53821 cgtcatccaa cgtggtgagt ttatcggtgg tgtgggtcac cctgaaatgg gtcattatta
    53881 tgttgctaga cacccaatgg atattgaaaa agagtttaag ggtgtttgtc ctttccataa
    53941 gggatgtcta gaaggttatg cagctggtcc aagtttggaa gctcgtacag gtgtacgtgg
    54001 ggaaactatt gaactcaaca accctgtttg ggatgttcaa gcctactata tcgctcaagc
    54061 tgcggttaat gcgacagtga ctttccgccc agacgtgatt gtctttggtg gaggggtcat
    54121 ggctcaacaa catatgctgg accgtgtccg tgagaaattt acatctcttc ttaatggtta
    54181 cctaccagta ccagatgtgc gtgactatat cgtgacgcca gcagtcgcag gaaatggttc
    54241 tgccacactt gggaactttg ttcttgcaaa agaagtttca aaataaagca caaaatccgc
    54301 ttgggaaacc aaacggattt tgtggttgaa aacaatattt ttgagccttt ccttaagtga
    54361 ttacggacgg tagcgacttt cttcgaaatt ccatacctaa actttgagac actaggctca
    54421 aagtttccga atacctgaaa ccattagatt tcaggtgttt ctatcacggc ggaaaggcta
    54481 ggtaagtcct cgcctcacta tcgaaaaata tgcatgattt ccataccaaa gtatatttag
    54541 tatcaagcta tagttaatct acgctttaaa aatccacttg ggaaaccaaa cggatttttt
    54601 acgtgtcaaa gcatttgcca gaaaaagtca ataatatagg tcaaaccgta ggtataaacc
    54661 acgagggtaa agggtttggt cagaatgatg atggtcatgt agcgcttgaa actcatcttg
    54721 gtcagggcag ccagcataca gagaaagtca gctgggctaa tgggccaaat catcataaaa
    54781 ataaagaagc ggtcaaaacg attgccctta tctagccagc cgatgtactt gtcgtaggtg
    54841 cgcttgctga cgacagactg gacaaaggca gctccgtata ggcgcactag ataaaagata
    54901 atggcacagc caatcacgat gccgatatag ttgtagatag tcccgatgat gtgcccgtag
    54961 ataaagaccc cagccaccga ggtcaaggcc cctggaatga tagggacgac agtctgtaaa
    55021 atctgtaaaa agataaagag aggtggaccc cagatgcctg cctgctggat aaaggcagag
    55081 agggtttcct tggattgtaa aatcccagcc tgataagccc aaatacagaa aatcaaactc
    55141 ccaaccccac cgacaatcga tgagatattg ataactcgct gcagaagggg agaaacagct
    55201 ttcatttgtt tatcctgtga catgtaaact cctcatagat agtatatttc tactatacca
    55261 tattttggag gagaaagggg gaatgagtct tttttgataa ggaatagaaa gtaaatagcc
    55321 cttcgagact tagaataggt ctgtcaacta aaggttatat gcattctagg tttcgaataa
    55381 tcgcaattcc atgaatttaa aagcattcta agtttcgaat agcttatctg agataatttt
    55441 gaggcattcg cgctttcgaa tagtcatttt ccctaaagtt tagatgtatt ctgaagctag
    55501 aaagactaaa atctaaaagt agtaagagtc tctctctgat ggacgtaatt tatggctagt
    55561 atgaatcctt tgaattgtta gttaatttta atattaatca gttctgaaat aattactaaa
    55621 tatagttaga tggtgaatta attattgcta aatttcaagt tcaagttagt catccagaag
    55681 tcttctctgg gggacttgta gttcaagcat tttttaggat agttgttaat ccacttttcg
    55741 atgaatgcga cttcctttgt agtcgttttc ttagttccct gaggtaacca tctatgaatg
    55801 aacttgttgt gatttttatt agatcctata gtggtgtgca taatagatat aatagattga
    55861 aactagaata gtacgcatct acttctaaaa cattgttaga aatcgatttg actgtcccga
    55921 tctatttgtc ctgtttttat ttcattttgc tatataatcc ttagaaaaca tatgggacaa
    55981 gcggttgaat tccgttccgt ccattagtag ataaaggatt actccttctt gaaatgacag
    56041 atgaacttgt ttcttataaa aatgttgtct gaaactattc gcttttttcc agaagtttta
    56101 gaggaagaaa actttatgag gaaaaaggag ttactcaaat aacaattcag gattaaaaat
    56161 agacagttga ggagcggaag gtataaatta agtttgctgc tgtataatgg atttatcact
    56221 aatactcttc gaaaatctct tcaaaccacg tcagcttcgc cttgccgtag atatagttac
    56281 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttt
    56341 tatctgcaac ctcaaagctg tactttgagc agtctacggc tagcttccta gtttgctctt
    56401 tgattttcat tgagtataaa agtgctccag gccatatttt acacagcaat agtcttctaa
    56461 aaatgaacaa aaaacattgt aaaggctatc aaaaaggagt ataatgagtg caagaaattt
    56521 cggaggtgaa agatgctaga agtaagaagt ctagagaaaa gttttggatc caagcaagtt
    56581 ttgtttggta ttgactttca agcgcgacca ggtcgtattt tgggactagt cggaaaaaat
    56641 ggtgctggaa aaacaacgat tttccatagt attttaaaat tcctagaata tcagggagaa
    56701 atcggtctgg atggtcagga tattcgtcag gagacctatg ctcggattgg ttatctgcct
    56761 gaagaacgca gtctcatgcc taaattgaca gttcttgaac aagttcgcta cttggcgact
    56821 ctaaaaggca tggatgccaa agaagtcaaa gaaaaactcc ctcaatggat gaagaggttg
    56881 gaagtgaaag gaaagctggc agataaaatc aagagtttgt caaaaggaaa tcagcagaag
    56941 attcagctca ttattactct gattcatgaa ccagacctga ttatcttgga tgagcctttt
    57001 agtggattgg acccagttaa tacagaattg ctcaaacaag tcatttttca ggaaaaagag
    57061 cgcggagcaa ccattatctt ttctgaccat gtcatgacca atgttgagga actttgtgac
    57121 gatattctga tgatccgaga tggccgtgtg gtcttgcacg gaccagttca ggatgtccgc
    57181 aatcaatacg ggaaaacacg tctctttgtt tcaagtgaac gaagcaagga agaattggaa
    57241 aatcttcctc atgtcaaaca ggtgagcttg accaaacaag gcagttggaa attgattttg
    57301 gaggatgaga gcgctggaag ggaactcttc ccaatcttga ctcaaggtca atatatcgca
    57361 acatttgacc aacaagcgcc aactatcgat gaaatcttta aactagaatc aggagtggaa
    57421 gtatgagaaa tatgtgggtt gtaatcaagg aaacctatct tcgacatgtc gagtcatgga
    57481 gtttcttctt tatggtgatt tcgccgttcc tctttttagg aatctctgta ggaattgggc
    57541 atctccaagg ttcttctatg gctaaaaata ataaagtggc agtagtgaca acagtgccat
    57601 ctgtagcaga aggactgaag aatgtaaatg gtgttaactt cgactataaa gatgaagcaa
    57661 gtgccaaaga agcaattaaa gaagaaaaat taaaaggtta tttgaccatt gatcaagaag
    57721 atagtgttct aaaggcagtt tatcatggcg aaacatcgct tgaaaatgga attaaatttg
    57781 aggttacagg tacactcaat gaactgcaaa atcagcttaa tcgttcaact gcttccttgt
    57841 ctcaagagca ggaaaaacgc ttagcgcaga caattcaatt cacagaaaag attgatgaag
    57901 ccaaggaaaa taaaaagttt attcaaacaa ttgcagcagg tgccttagga ttctttcttt
    57961 atatgattct gattacctat gcgggtgtaa cagctcagga agttgccagt gaaaaaggca
    58021 ccaaaattat ggaagtcgtt ttttctagca taagggcaag tcactatttc tatgcgcgga
    58081 tgatggctct gtttctagtg attttaacgc atattgggat ctatgttgta ggtggtctgg
    58141 ctgccgtttt gctctttaaa gatttgccat tcttggctca gtctggtatt ttggttcact
    58201 tgggagatgc tatctcactg aataccctgc tctttatttt gatcagtctt ttcatgtacg
    58261 tagtcttggc agccttccta ggatctatgg tttctcgtcc tgaggactca gggaaagcct
    58321 tgtcgccttt gatgattttg attatgggtg gtttttttgg agtgacagct ctaggtgcag
    58381 ctggtgacaa tctcctcttg aagattggtt cttatattcc ctttatttcg accttcttta
    58441 tgccgtttcg aacgattaat ggctatgcgg agggagcgga agcatggatt tcacttgcta
    58501 ttacagtgat ttttgcggtg gtagcaacag gatttatcgg acgcatgtat gctagtctcg
    58561 ttcttcaaac ggatgattta gggatttgga aaacctttaa acgtgcctta tcttataaat
    58621 agaagagcct tgcgaaagcg aggtttttaa aggtgaaaag ggtggaatca cgaacctaat
    58681 tatgtacaca ttatgtaaac aggttgcttg aaaactcaat tgtatagtga actgaatctg
    58741 gaataggata atattacttc taaaacattc ttataaattg atttgaattc caaaatccca
    58801 tcgttccgtt cttatttcat tttgcgatat agcgaaagga aataagtcag ctcacaaaaa
    58861 acgcataata tcaaggattt ttaacacttg atactatgcg ttttctaatt ttaaagactt
    58921 tttgcctggt ctcttttgtt ctatgagtat gttacatatc taggtaaaaa ttatttaaag
    58981 caaattaacc ttatttctca agatgtagta ggttccgaga taaaagatag ctatgaatat
    59041 gagttcttta acaatggcta tacctgctcc catatagaaa tggtcattga gtcctaccag
    59101 tgaattgaca tagaaattgg aactaagatt gaagaaaagt tcaataaatc caatgacgat
    59161 ttggatacca atgtaggctg caacagcgag tgctgtacgg tattcattga aaagctgtcc
    59221 aatggaaata gccaggtaga tgcagaggat tcctgaaatg gtatttagta ggaaggatat
    59281 acctgtaaga aagatctgag ggagatgtgt ttctacaaat gtaatcacat aagaaagagg
    59341 aatccattct ggagctgtta aagccagaat aataacagca cttagagcca atacagcggt
    59401 gctaatcaat gaccagataa aggcaccgat tagtttggct gtgatgatat ggtgttcaga
    59461 aactggcaag gtcaaagtca gatagccttg tcggtcgtag acactacctt tgaagcgttt
    59521 aataatcaag aaaatggttg aaatcgcaag tgtaagcatc aagccaccaa agactgtagc
    59581 tagaaaaagt agcatagtag cctgactttc ttggtaaggt agatttttaa agccttgtgt
    59641 ctgtattccg atgagggcag aaaggactag cacggctgcg tagagggcta aataccactt
    59701 gttaacattt ttaaattcgt agtgaactaa attccaaaac ataaataatc tcctttgctt
    59761 aggccttaaa ttcctgacgg aagagttggt caatggattc acctgactcg tagcgaatat
    59821 catctacatt tccttgacgg acgacttttc cgtcttttag gaagacaatt tcatccaaga
    59881 ttggctcgat atcagaaatc aagtgggtag aaatcaaaac ggtagaagtt ggtgagtagt
    59941 tgttgataat ggtattgagg atataagcac gggctgctgg atccacccca ccaatgggtt
    60001 catccaaaac atagagacga gcatcacggc tcataaccaa aatcagttga accttttctt
    60061 tgtttccttt tgatagtttc ttgagacgac tattttcatc aatgcccagg tctgcaagta
    60121 gatgatgagc gcgttcaaga ttgaaatctt tatagaaggt cttgaagtag gttagggctt
    60181 ctttgacctt catttgctca ttgagatagg tcgtatcagg caaataagct acaacggcct
    60241 tggttgctgg gcttgggtcc atgtcgttga tgaggacacg tccttgatct ggttgtaaga
    60301 ggccattaat tagtttaatc agggttgttt ttcctgagcc gtttggccca agaaggccga
    60361 caatttttcc agctggaatg tcaagagaaa cattttcaag ggctggtgtt gctccatatg
    60421 atttggatac attttcaaat gctagtaatg acataggctt aaactccttt aatataatca
    60481 ctgactacgc ctggtagttc ttctttttca tagccaaaat gggtcatgga ggaaacgaag
    60541 tgttccaatt cttcttctga taattgtttg cgtgactggg cgattagctc cttatcctta
    60601 gtcacaaatc gtccagttgt tcgcttgctg tagacaaatc cttctcgttc aaggtctgat
    60661 aaggctcttt ggatggtatt gggattgaca ccagcctcgc tagctagctc cctcacggtt
    60721 ggaagttgtt gattgggttc cagtgtatgg gaaacaatct gaagcttgat tttctccata
    60781 atctgtaaat agatgggttt tttgttgtca aatgtccagg acatcttagt ctcctttctt
    60841 ttaccctttt gtcttaatta aataatacaa caaaacaaaa aacttgtcaa gcaaaaagaa
    60901 gaattgtttt gggaatcgct taaaaaatgg tataatgaaa agaaaacgat aaggagggaa
    60961 aggatgcgtt gtccaaaatg tggggctacc aagtcaagtg ttatcgatag tcgccaagca
    61021 gaagaaggga acaccattcg tagaagacgt gagtgcgacg aatgccaaca ccgttttaca
    61081 acctacgaac gagtagaaga aagaacctta gtggttgtta aaaaagatgg cacacgggaa
    61141 caattctcca gagataaaat ctttaatggg attatccgct cagcccagaa acgtcctgtg
    61201 tcaagtgatg aaatcaacat ggtagtcaat cgtatcgaac agaaactccg tggtcgaaat
    61261 gaaaatgaaa ttcaaagtga ggacattggt tcactcgtca tggaggagtt ggctgaattg
    61321 gacgagatta cctatgtacg ttttgctagt gtctatcgta gttttaagga tgtcagtgag
    61381 ttagagagct tgctccaaca aatcacccag tcctctaaaa agaaaaagga aagataaatg
    61441 aagccaattg accgtttttc ttatctaaag aataatcggg tgtcgcaaga tacctcatct
    61501 ctggtacagt gctacctccc gattatcggt caggaggcac tgagccttta tctttataca
    61561 atcagttttt gggataatgg tagaaaggaa tatctttttt caagcattct caaccatctt
    61621 aactttggga tggatagact gataaaatca ttgaaaatct tatctgcttt taatctcttg
    61681 accctctatc aaaaggggga tgtttatcag ctagtcctcc atgctcctct atctagtcaa
    61741 gacttcttgg agcatcctgt ttatcgcaga ctcttagaga aaaagattgg cgatgtagct
    61801 gtggaggatt tgaaagttga aagtgctgat ggtgaagaaa tacctgtctc actcaatcaa
    61861 gtctttccag aattggcaga actaggcagt caagaagacc ttggtctcaa gaagaaagtg
    61921 gccaacgatt ttgacttgga ccattttcgc cagctgatgg ctcgagatgg acttcgtttt
    61981 gcggatgagc agtccgatgt cttaaacctc tttgctattg ccgaggagaa gaaatggact
    62041 tggtttgaaa cctatcaatt ggccaagtca acagctgttt ctcaggttat ttcaaccaaa
    62101 cgcatgcggg aaaaaattgc tcaaaaacca gtttcctctg actttagtct taaggaaaca
    62161 accattatca aagaagccaa aagtaaaact gccctgcagt tcttggcaga aatcaagcaa
    62221 acacgcaagg gaaccattac ccaaacagaa agagaactct tgcaacagat ggctggcttg
    62281 ggcttgctgg acgaagtcat caatatcatt cttttattga cctttaataa ggtcgattcg
    62341 gcaaatatca atgagaaata tgccatgaag gtagccaatg actatgccta tcaaaagatt
    62401 cattcggcag aaaaggcagt cttgcgcatc cgtgagcgag gacagaaagc aaaaatacaa
    62461 aaacagaatc agactgcccc agtaaaaacc aatgttccta aatggagtaa tcctgaatat
    62521 aagaatgaaa ccagcgagga aactcgtctg gaactagaac gtaagaagca agaactatta
    62581 gctcgattag aaaaaggagg agattagatg gaaagtgtcg gagacgtact caaacgtcaa
    62641 cccagccgtt tttattatca agatttggtc cagaaaatca tgaaggaccc tgatgttgcg
    62701 gcttttatcc agcaagaatc cttgactcca gaggaattaa atcgcagtat ctccaagttt
    62761 aatcagtaca tcaccgagcg tgacaagttt ctccgtgggg atacggatta tattgccaaa
    62821 ggctacaagc cgattttggt taagaatcat ggctatgcag atgtttcata tgaagaaact
    62881 cctgagctaa tcgcggctga aaaagaagcg gctattaaga accgtctcaa gttaatcaat
    62941 ctaccagcca gtctcaagaa agctagtttg gctcaagttg acttggatga tttggggcgc
    63001 ttaccagttt ttgaaaagct actagccttc gtggagcaat atccagctat tcgaaaaggt
    63061 ctttacttat atggagactt tggtgtgggt aaaagtttca tggtggcggc cttagctcat
    63121 gatttatcag aaaaacgtgg tgtttcatca actctcctcc actatcctag ctttgtcatt
    63181 gatgtcaaaa atgctatcag tgatggcaat gttaagacct tggtggatga gattaagctg
    63241 tctgaggtcc tgattttaga tgatattggc gccgagcaat caaccgtttg ggtgcgtgac
    63301 gaaatcctgc aggtcattct ccaatatcgg atgcaggaaa atttaccgac ctttttcaca
    63361 tccaacttca actttgaaga tttggagaag cattttgcga aagtgaaaca tggaaatgac
    63421 gaaacctggg aagccagacg ggtcatggaa cgcatccgtt atttggctga ggagactcgt
    63481 ttagaaggag taaaccgtcg atgacagaaa ccattaaatt gatgaaggct catacttcag
    63541 tgcgcaggtt taaagagcaa gaaattcccc aagtagactt aaatgagatt ttgacagcag
    63601 cccagatggc atcatcttgg aagaatttcc aatcctactc tgtgattgtg gtacgaagtc
    63661 aagagaagaa agatgccttg tatgaattgg tacctcaaga agccattcgc cagtctgctg
    63721 ttttccttct ctttgtcgga gatttgaacc gagcagaaaa gggagcccga cttcataccg
    63781 acaccttcca accccaaggt gtggaaggtc tcttgattag ttcggtggat gcggctttgg
    63841 ctggacaaaa tgccctgctg gcagctgaaa gtttgggtta tggtggtgtg attattggct
    63901 tggtacggta caagtcagaa gaagtggcag aactctttaa cctgcctgac tacacctatc
    63961 ctgtctttgg gatggcacta ggtgttccaa atcaaactca tgatgtgaaa ccgagactgc
    64021 cactagataa tgtagtcttt gaggaagaat accaagaaca gtcaactgag gcaatccaag
    64081 cttatgaccg tgtgcaggct gactatgctg gagcgcgtgc gaccacaagc tggagtcagc
    64141 gtctagcaga acagtttggc caagcagaac caagctcaac tagaaaaaat cttgaacaga
    64201 agaaattatt gtagaaagtg agaaattatg gccctaccaa ctattgccat tgtaggacgt
    64261 cccaatgttg ggaaatcaac cctatttaat cggatcgctg gtgagcgaat ctccattgta
    64321 gaagatgtcg aaggagtgac acgtgaccgt atctatgcaa cgggtgagtg gctcaatcgc
    64381 tcttttagta tgattgatac aggaggaatt gatgatgtag atgctccttt catggaacaa
    64441 atcaagcacc aggcagaaat tgccatggaa gaagcagatg ttatcgtttt tgtcgtgtct
    64501 ggtaaggaag gaattactga tgcagacgaa tacgtagctc gtaagcttta taagacccac
    64561 aaaccagtta tcctcgcagt caacaaggtg gacaaccctg aaatgagaaa tgatatctat
    64621 gatttctatg ctctcggttt gggtgaacca ttgcctatct catctgtcca tggaatcggt
    64681 acaggggatg tgctagatgc gatcgtagaa aatcttccaa atgaatatga ggaagaaaat
    64741 ccagatgtca ttaagtttag cttgattggt cgtcctaacg ttggaaaatc aagcttgatc
    64801 aatgctatct tgggagaaga ccgtgttatt gctagtcctg ttgctggaac aactcgtgat
    64861 gccattgata cccactttac agatacagat ggtcaagagt ttaccatgat tgatacggct
    64921 ggtatgcgta agtctggtaa ggtttatgaa aatactgaga aatactctgt tatgcgtgcc
    64981 atgcgtgcta ttgaccgttc agatgtggtc ttgatggtca tcaatgcgga agaaggcatt
    65041 cgtgagtacg acaagcgtat cgcaggattt gcccatgaag ctggtaaagg gatgattatc
    65101 gtggtcaaca agtgggatac gcttgaaaaa gataaccaca ctatgaaaaa ctgggaagaa
    65161 gatatccgtg agcagttcca atacctgcct tacgcaccga ttatctttgt atcagcttta
    65221 accaagcaac gtctccacaa acttcctgag atgattaagc aaatcagcga aagtcaaaat
    65281 acacgtattc catcagctgt cttgaacgat gtcatcatgg atgccattgc catcaaccca
    65341 acaccgacag acaaaggaaa acgtctcaag attttctatg cgacccaagt ggcaaccaaa
    65401 ccaccaacct ttgtcatctt tgtcaatgaa gaagaactca tgcacttttc ttacctgcgt
    65461 ttcttggaaa atcaaatccg caaggccttt gtttttgagg gaacaccgat tcatctcatc
    65521 gcaagaaaac gcaaataaaa aagtagaatc tggaatgaca gttccggatt tttttgatat
    65581 aataaaataa tagaaaacgc tatcaaaaga aggggggatg tcggtgatgg aacatttgtt
    65641 taaattctta cttttagcac cgtactttta ttttgataac tggattgaaa aggccaacag
    65701 aaatagtaag ttttttccaa ttttttatta tttttactgg ttttacatcc ccttctattc
    65761 tctttttagc cttgcttgga cagttgtttc agttctgttt ttcaataccg tcttgagaaa
    65821 tgtgacagat atcaagttat ggggcatttg gtttcttttt attctgctag ctattggtat
    65881 gaattggtta acttattcct gtttcaaaga aatgtttcgc ttgagacagg aactagggaa
    65941 gtctaagggt ggaaggcatt gatttatatc ggtttctatt tgtaggaggt ggcttatggt
    66001 acctctaaaa tcatttatta cacgctattc caaggtttat attggtaata acatttaata
    66061 gaacgaaact aaagaaaata atttaaaaga ggaggtttgt gatggaacac ttgtttaaaa
    66121 tgataatctt attaccctgt ttttactttt tcagctggat tgacaaggat aatagagaaa
    66181 gtaaattttt cccaattttt tactattttt actggattta catcaccctc tatgctcttt
    66241 ttagccttgc ttggacagtt ttttcagttc tgtttttcaa tatcgtcttg agaaatttga
    66301 cagatatcaa gttatggggt atttggctat tattactact tatcgctttt gctagtgact
    66361 ggttagacta tatctgtttc aaaaaaatgc ttgacttgag acgggaacta gggaagtcta
    66421 aaggcggaag gcattgattt atactcttcg aaaatctctt caaaccacgt caacgtcgcc
    66481 ttggattata tatgtaactg acttcgtcag tcttatctac aacctcaaag cagtgctttg
    66541 agcaacttgc ggctagtttc ctagtttgct ctttgatttt cattgagtat tatattactt
    66601 tctatttgta ggaggtggct tatgaagatt cctctcttaa ctttggcaag gcataaattt
    66661 gtttatgtct tgcttacttt gctttttctt gctttggttt atcgtgatgt tttgatgact
    66721 tatttctttt ttgatattca tgcgcccgat ctagctaaat tcgatggaca agcaattaaa
    66781 aatgacttat taaaatcagc attagatttt cgtattctcc agttcaatct aggtttttat
    66841 caatcattta ttattccaat catcattgtt ttgctaggtt ttcaatatat tgagctgaaa
    66901 aataaagttt tacgattgag tattggaaga gaagtgagtt atcaagggtt aaaaagaaag
    66961 ttgactttgc aagttgcaag tatcccttgt ttgatatatt tagtgactgt gctgataatt
    67021 gcaattttaa ctcatttctt tgggactttt tctcctcttg gatggaattc tctattttct
    67081 gatgggagta gtttacaaag gctcctagat ggagagataa caagctattt gttctttact
    67141 tgtgtcctac taatcggtat tttcatcaat gcagtctatt ttttacaaat agttgattat
    67201 ttaggaaatg tgactcgttc ggcaatcacc tatttgatgt ttctttggct tggttctatg
    67261 ctgctctata gtgccttgcc ttactatatg gttcctatga cgagtttgat gcaagctagc
    67321 tatggggatg taagtttgat gaaactcttt actccttata tcctttatat tgtctcttac
    67381 atggtgcttg aaaaatatga agataatgtt taagaatttt aacaatattt tgctaaagag
    67441 aaagattgtt ttactacttc gtatagttct gatgatgatt ttgataaacc atctattgtc
    67501 aacagcggtt caaaagcagg atgctgttat ctttttcaag agagaattga tttcaatttt
    67561 ttcctataat gactattctg aagtgaattt agaaatcccc aaactcttgt taaacctttc
    67621 gcttttcatg gtaggatggc tctctgtcat tttacttgaa agtgatttgg cagaccatta
    67681 ccatcacttg attcgctatc aatcaagctc ctttttcgat tatacaagga aacgattggt
    67741 tgtcatttct aaatttttta ctcaagattt gtttgtctgg tttcttggtt tacttcctct
    67801 aggaattcat ttcaaaacag tcgcactttt ctttttactt gctcagttaa tgatgttgta
    67861 cttactactg tcttatctga tagcactgat tagtgcgggc gctggttttt ccttttttct
    67921 ctatttttta gcatttgtgg gacaagaatg gatgatggat catattgtaa cagtgtattt
    67981 actactctta agtttattag ttatgttgat tgttagtcgc ttggaagaga aatttaagaa
    68041 aggataaacg atgagacttg aaattataaa tggacagaaa atttatagga aaagacctat
    68101 tttaaatcag ttgaatttgg tgtttcaatc aggaaaaatt tatggactta aaggtgataa
    68161 tggatctggc aagacggttc ttttaaagat acttgctggt tatattaagc ttgacaaagg
    68221 aaaagttctt caagatggta aagtttacgg ggtaaaaaat cattatattc aggatgcagg
    68281 aattttaatt gaaaaagtcg agtttttatc tcatttatcc ctgagagaaa atttggaact
    68341 gttaaggtat ttttcatcta aagttacgga aaaaagaatt gcctattgga ttcaatacta
    68401 tgatttacag gaatttgaag acattgaata ccgtcattta tccttaggaa caaagcaaaa
    68461 aatggccttg attcaagcct ttatttcctc tccttctata ctctttctcg atgaacctat
    68521 gaatgctttg gatgagaaga gtgtgaggtt aaccaaacag gtcattttat cttacctgaa
    68581 aaaagaaaat ggtctggtta tcctgacgtc gcacatatcg gaagatattt cagacctttg
    68641 tacagatgta ttagttgtcg aaaatggaca tatacaaatg taaaggatat acaatcctag
    68701 gagatggctt atggcacatc taaaatcatt tattacacgc tattccaagg tttatattgg
    68761 tttagttctg ctgatctggc tgtctttctt ctttatccct tgggataaac cacttctggg
    68821 gataaggatt gacatcttca tcatacagaa aatcttgcta gcttttggaa ttctgtccat
    68881 tctcatggcc ttgctgtcca agaaagtcag tctctttgtt tttggactga tttgctgtct
    68941 ttctctttgg attaacttat ttatcacact tgccattttg ccgatttttg gcaattaaac
    69001 agtcataaaa gtcggagagg ttagcttgaa aactaacctc tttttccttt tcaaaatggg
    69061 gattcttcct tgaaaataat cagtaattgt gctaaaatta aaggaacatt ctaaaatatt
    69121 cggaatttaa agtaaggaaa aacatggcta atattttaaa aacaattatc gaaaatgata
    69181 aaggagaaat ccgtcgtctg gaaaagatgg ctgacaaggt tttcaaatac gaagaccaaa
    69241 tgactgcttt gactgacgac caactaaaag caaaaacagt tgaatttaag gaacgttatc
    69301 aaaatggaga atcactggat tcattgcttt acgaagcatt tgcggttgtc cgtgaaggtg
    69361 ccaaacgtgt cctaggtctc ttcccttata aggttcaggt catggggggg attgttcttc
    69421 accatggtga cgtgccagag atgcgtacag gggaagggaa aaccttgact gcgaccatgc
    69481 cggtatacct caatgccctt tcaggtaaag gggttcacgt agttacggtt aatgaatacc
    69541 tgtcagaacg tgacgcgact gagatgggtg aattgtactc ttggcttggt ttgtcagtag
    69601 ggattaactt ggctaccaaa tctccaatgg agaaaaaaga agcctatgag tgtgatatta
    69661 cttactcaac taactcagaa atcggatttg actaccttcg tgacaacatg gtcgttcgcg
    69721 ctgaaaacat ggtacaacgt ccgcttaact atgccttggt cgatgaggtt gactctatct
    69781 tgattgacga ggctcgtaca cctttgattg tatcaggtgc caatgcggtt gaaaccagtc
    69841 agttgtatca catggcagac cactatgtaa aatctttgaa caaagatgac tacatcatcg
    69901 atgtgcagtc taagactatt ggtttgtctg attcagggat tgacagggct gaaagctact
    69961 tcaagcttga aaacctctat gacatcgaaa acgtggcttt gacccacttt atcgataacg
    70021 cccttcgtgc caactacatc atgcttctcg atattgacta tgtggtgagc gaagagcaag
    70081 aaatcttgat tgtcgaccaa tttacaggtc gtaccatgga aggtcgtcgt tattctgatg
    70141 gattgcacca agctattgaa gccaaagaag gtgtgccaat ccaggatgaa accaagacat
    70201 ctgcctcaat cacgtaccaa aaccttttcc gtatgtacaa gaaattgtct ggtatgacgg
    70261 gtacaggtaa gactgaggaa gaagaattcc gtgaaatcta caacattcgt gttattccaa
    70321 tcccaacaaa ccgtcctgtt caacgtattg accactcaga ccttctttat gcaagtatag
    70381 aatctaagtt taaagcggtt gtcgaagacg ttaaggctcg ttaccaaaag ggtcaacctg
    70441 tcttggttgg tacagtagcg gttgaaacta gtgactacat ttctaagaaa ttggttgcag
    70501 ctggtgttcc tcacgaagtc ttgaatgcca aaaaccacta tagagaagcc caaatcatca
    70561 tgaatgctgg tcaacgtggt gccgttacca tcgcaaccaa catggcgggt cgtggtaccg
    70621 acatcaagct tggtgaaggt gttcgtgaac ttggaggact ttgtgttatt ggtacagaac
    70681 gtcatgaaag tcgtcgtatc gataaccagc ttcgtggacg ttcaggtcgt caaggagatc
    70741 caggtgagtc acaattctac ctatctcttg aagatgattt gatgaaacgt tttggttctg
    70801 aacgcttgaa gggaatcttt gaacgcttga acatgtctga agaggcgatt gagtctcgca
    70861 tgttgacgcg tcaggttgaa gcagctcaga aacgtgtcga aggaaataac tacgataccc
    70921 gtaaacaagt ccttcaatac gatgatgtca tgcgtgaaca acgtgagatt atctatgctc
    70981 aacgttacga tgtcatcact gcagatcgtg acttggcacc tgaaattcag tctatgatca
    71041 aacgcacgat tgaacgtgtc gttgatggtc atgcgcgtgc caaacaagat gaaaaactag
    71101 aggcaatttt gaactttgct aagtacaact tgcttcctga agattctatt acgatggaag
    71161 acttgtcagg cttgtctgat aaggccatca aggaagagct tttccaacgt gccttgaagg
    71221 tttacgatag tcaggtttca aaactacgcg atgaagaagc agttaaagaa ttccaaaaag
    71281 ttttgattct acgagtagtg gataacaagt ggacagatca tatcgatgcc cttgatcaat
    71341 tgcgtaacgc ggttggactt cgtggctatg ctcagaacaa ccctgttgtt gagtatcagg
    71401 cagaaggttt ccgtatgttt aatgatatga ttggttcgat tgagtttgat gtgacacgct
    71461 tgatgatgaa agcacaaatt catgaacaag aaagaccaca ggcagaacgt catatcagta
    71521 caacagcgac tcgcaatatc gctgctcacc aagcaagtat gccagaagat ttggatttga
    71581 gccagattgg acgcaatgaa ctttgcccat gtggttctgg taagaaattt aaaaactgtc
    71641 acggtaaaag acaataaaat gagatagttt agaggcggat atcttgtgaa aagtaaattt
    71701 ttactgggta tccgtttgct ttataaggag atgagttatg gtatttacag caaaaagctc
    71761 taaaataaat atagaagaag ttcgtgcctt gtcaaaatta gaaggtcagg ctttggagag
    71821 gaaatcacag cgagatcaag agctagaagc cattatacgt ggagaagacc agcgaattct
    71881 cttggtaatc gggccatgct catctgacaa cgaagaagct gtccttgaat acgctaagcg
    71941 tttggcagtc ctacaagaag aagtggcaga tcgtatcttt atggttatgc gtgtttatac
    72001 tgccaaaccc cgtaccaacg gagatggcta taagggcttg attcaccagc ctaacgcgac
    72061 agaagcgcct agtcttatca atggaatcaa agccgttcgc catcttcact atcgtgtcat
    72121 cacagaaaca gggatgacaa ctgctgatga aatgctttat cctgaaaacc ttccgcttgt
    72181 agatgatttg atttcttaca tggcagttgg tgcccgttca gttgaagacc agcaacaccg
    72241 ctttgtggca agtggggcag gattttctac tggttttaaa aatccaacct ctggaaatct
    72301 caatgtcatg tttaatggga tttatgctgc tcaaaacaaa caaagtttcc ttttcttagg
    72361 aaaagaagta gaaacaactg ggaacccgct ttcacacgct attcttcgtg gtgctcttaa
    72421 tgagtatgga aaaaatattc ccaactacta ttatgacaat ttaattgata ccattgccca
    72481 gtatgagaaa atgggcttgg aaaatccttt tatcatcatt gataccaatc atgacaattc
    72541 tggtaagcag tatattgaac agatccgaat tgtccgccag accttgatta accgtgcttg
    72601 gaatgaaaaa attaagcagt tcgttcgtgg ttttatgatt gagtcttatc tggaagatgg
    72661 tcgacaaaat gagccagaag tatttggtaa gtctatcaca gacccttgcc tgggttggga
    72721 taacacagaa gctcttgtca gagaaattta caaaacgtta ggagaataag atggcattta
    72781 ttgaaaaagg tcaagaaatc gatatggaag tcatcaaggc tgaaacccaa ttgtctgcgg
    72841 aagccttgag actcaaggaa agccgtgaca gggaattggc agatattatt tcaggggaag
    72901 atgaccgtat tctcttggtg attggtcctt gctcttctga taatgaagag gcggtcttgg
    72961 aatatgctcg ccgtttatcc gccttgcaaa agaaggtagc ggacaagatt ttcatggtca
    73021 tgcgcgtgta tactgctaag cctcgtacca atggagacgg ctataaagga ttagttcacc
    73081 agccagatac ttctaaggct ccaagcctga ttaatggctt gcaggctgtg cgccagttgc
    73141 actaccgcgt gattacagag actggtttga caacggcaga tgagatgctt tatccgtcaa
    73201 atctgatctt ggtggatgac ttggtcagct accatgccgt tggagctcgt tctgtggaag
    73261 accaagagca ccgctttgtg gcttctggga ttgatgcacc agtagggatg aaaaatccaa
    73321 cctcaggaaa tttgggtgtt atgtttaacg ccatctatgc tgctcaaaac aagcaaacct
    73381 tcctttatca tgggcaggaa gttgagacat caggtaatcc tttggcccat gttatcctcc
    73441 gtggagcagt caacgagtat ggcaattata tgccgaatta ctactatgaa aacctactcc
    73501 aagccattga acgctatgaa accatgggac ttgaaaatcc ttttatcctc attgacacca
    73561 accatgataa ctcaggcaag caatatatgg agcagattcg aattgttcgc cagaccttgc
    73621 agaatcgtga ttggaatgag aaaattaaaa agacggttcg aggatttatg attgaatctt
    73681 acctagcaga tggtcgtcaa aaccaaccag agatctttgg ttgctctatt actgaccctt
    73741 gcctaggttg ggaaaataca gaggccttgg tagaagagat ttatgttacc ttgacaaaat
    73801 aagtgaaaag gatggagttg gggaatctca actccttttg atgagaatga tagttggaca
    73861 cggaattgac atcgaagaat tggcttcgat agaaagtgca gttacacgac atgaaggatt
    73921 tgctaagcgt gtactgaccg ctcaggaaat ggagcgcttc accagtctca aaggacgcag
    73981 gcaaatagaa tatttagctg gtcgctggtc ggctaaggag gccttttcca aggctatggg
    74041 aacgggcatt agcaagctcg gttttcagga tttggaagtc ttgaacaatg aacgtggggc
    74101 gccttatttt agtcaggcac cattttcagg aaagatttgg ctgtctatca gccacaccga
    74161 tcagtttgtg acagccagtg tcattttgga ggaaaatcat gaaagctagt ccacatagac
    74221 caaccaaggc tctgattcat ctgggagcta ttcgacaaaa tattcagcaa atgggggctc
    74281 atatccctca aggaacgctc aagttggctg tggttaaggc caatgcttat ggtcatggag
    74341 ctgttgccgt tgccaaggca attcaagatg atgttgatgg cttttgcgtt tccaatatcg
    74401 atgaagccat tgaactcaga caagctggac tcagcaagcc aattctcatt ttaggagttt
    74461 ctgaaatcga agctgttgct ctagctaaag aatatgactt caccttgaca gtggctggac
    74521 tggagtggat tcaagcactc ttagataagg aagtggacct aactggattg acagtccacc
    74581 tcaagattga ttcagggatg ggacggattg gttttagaga ggccagtgag gttgagcagg
    74641 ctcaagattt gctccaacaa cacggtgttc gtgttgaagg aatctttacc cactttgcta
    74701 ctgctgatga ggaatcagat gactatttta atgcccagtt agaacggttt aaaactattt
    74761 tagctagtat gaaggaagtt ccagagctgg ttcatgctag caattctgca acgactcttt
    74821 ggcatgtaga gactattttc aatgcggttc gtatgggaga tgccatgtat ggcctcaatc
    74881 caagtggagc ggtcttggat ttgccttatg atttgatacc ggccttgacc ttggagtctg
    74941 ctctggttca tgtcaagaca gttccatctg gagcttgcat gggatatgga gcaacttatc
    75001 aagcggatag cgagcaagtc atcgcgaccg tgccaatcgg gtatgcagat ggatggacaa
    75061 gagacatgca aaatttctct gtcttggtag atggccaagc ttgcccaatt gtcggcaggg
    75121 tttcgatgga ccaaatcact attcgattgc ctaagcctta cccactcgga accaaggtaa
    75181 ccttgattgg ctccaatggg gataaggaaa tcactgcaac tcaggtagcg acctaccgcg
    75241 taaccattaa ctatgaggtg gtttgcctcc tcagcgaccg tattccgaga gaatattatt
    75301 agaaaagaaa ggagtggagc atgaatctac atcaaccctt gcatgtcttg cctggtgtgg
    75361 gaccaaagtc agcagaaaaa tacgccaaac taggaattga aaacttgcaa gatctcttgc
    75421 tctactttcc tttccgttat gaagacttca aaaccaagca ggtgctggag ctggaagacg
    75481 gtgagaaggc agttctttct ggtcaggtag tgactcctgc tagtgtccag tattatggtt
    75541 tcaagcgcaa tcgcctgcgt tttagtctca agcagggaga ggtcgttttt gcggtgaatt
    75601 tctttaacca gccctatctg gctgataaaa tagagttggg agcaaccctt gctgtctttg
    75661 gaaaatggga ccgcgctaag gctagtctga ctgggatgaa ggttctggct caggtagaag
    75721 atgacctcca gcctgtttat cgtctggctc agggaatcag tcaggccagt ctggttaagg
    75781 tcatcaagac ggcttttgat cagggactgg acctcttgat agaagaaaat ctgccccagt
    75841 ctttactaga caaatacaaa ctcatgtccc gttgtcaggc agtccgagct atgcattttc
    75901 caaaggattt ggcagaatac aagcaggctc ttcgccgtat aaagtttgag gaactctttt
    75961 atttccaaat gcagctgcag acgctcaagt ctgaaaatag aattcaggga agtggtctgg
    76021 ttctggattg gtctcaggaa aaagtgacag cagttaaagc aagtcttcct tttgccctga
    76081 cccaagctca ggaaaagagt ttgcaggaaa ttttaactga tatgaagtcc gaccaccaca
    76141 tgaatcgtct cctacaaggg gatgtgggga gtggaaaaac ggtagtcgct ggcttggcca
    76201 tgtttgcggc agtgacagca ggttatcagg ctgccctaat ggtaccaaca gaaatcctcg
    76261 cagagcaaca ctttgagagt ttacagaacc tttttcccaa tttgaaactg gctctcttga
    76321 caggttcctt gaaagctgca gaaaagagag aagtcttgga gaccattgcc aagggtgagg
    76381 ctgatttgat tataggaact cacgctctga tacaagatgg ggtggagtat gctcgtcttg
    76441 gtttgattat tatcgatgag cagcaccgtt ttggtgtagg gcaaaggcgt attttacggg
    76501 aaaaaggtga caatccagat gtcctcatga tgacggcgac tcccattcca cggacgcttg
    76561 ccatcacagc ctttggagat atggatgttt ccattatcga ccagatgcca gcaggtcgga
    76621 agcctattgt gacgcgctgg atcaaacatg agcaactacc tcaggtcttg acttggttag
    76681 agggggaaat tcaaaaaggt tcccaagcct atgtcatctc tcctttgatt gaagaatcag
    76741 aagctctaga tttgaaaaat gccattgcct tatcagaaga gctgacggct cattttgcag
    76801 gcaaggcaga ggtggctctt ctacatggta ggatgaagag tgacgaaaaa gaccagatca
    76861 tgcaggattt caaggagaga aagacggata ttctggtttc gacgacggtt attgaggttg
    76921 gggtcaacgt tcccaatgcg actgtcatga ttatcatgga tgccgatcgc ttcgggctca
    76981 gccagcttca ccagcttaga ggtcgtgtcg gtcgggggga caagcagtcc tacgctgttc
    77041 tcgttgccaa tcccaagacg gattctggga aagaccgcat gcgcatcatg acagaaacga
    77101 ccaatggatt tgtccttgcg gaggaagatt tgaaaatgcg tggttctggt gagatttttg
    77161 gaaccagaca gtcaggactt ccagagttcc aagtggctga tattatagaa gattttccga
    77221 ttttagaaga agcaagaaag gttgctagct acattagttc tatagaagct tggcaagaag
    77281 atccagagtg gcgcatgatt gcccttcatc tggaaaagaa agaacatctg gattaagctt
    77341 tctctaagga aaacttaagc tagtttttag gtttggctct tatactaaag tcatcaaaaa
    77401 gaaacgagga ctctcatatg acagtaacga ttaaagtaaa ttaccaaacc actttccaaa
    77461 agaaggaagc aaaaaactag tataaacaga agagagagcg aaatgctctt tttcgtttct
    77521 aaaactactt tcagcccatc atcctaaaag taaagaatct aaattcactt tctatttatc
    77581 cttctttctt gcattgatta catagatatg ctacagttgt ggtaacgatt acaaaataaa
    77641 aggagcatgc tatgaaaaat ccagctttgc tagaagaaat taagacctat agaggaaggg
    77701 atgaggttcc ggaagacttt gatgctttct gggatgggga agtgaaaaat gtttccacgc
    77761 ttccatccta ccacttggag gaaagagatt tccacattcc tcaagtcaag tgctatgagt
    77821 taacatttga aggaagcaag gaaggaaagg tctatgcacg cattgttctt ccaaagagtg
    77881 aggagaaggt tccactaatc ttccattttc atggttatat gggacgtggc tgggactggg
    77941 ccgacatgct gggcttcacc gtagctggtt acggtgttgt ttccatggat gtgcggggcc
    78001 agtcaggtta ctcacaagac ggcttgcgtt ctcctttagg aaataccgtg aaggggcata
    78061 ttatccgtgg tgctatggaa ggtcgggacc acctctttta taaggatgtt tatctggata
    78121 tttaccagtt ggtcgaaatt gttgctagtc tgtctcaggt tgatgagaag cgtctttcta
    78181 gctatggtgc ctcacaagga ggggctctag ctctagttgc agcagcgctc aatcctcgaa
    78241 ttcagaaaac agttgccatt tatcccttct tgtcagactt cagacgggtg attgagattg
    78301 gtaatactag cgaggcttac gacgaacttt tccgctattt caagtttcac gaccccttcc
    78361 atgaaacaga ggaggaaatc atggcgaccc ttgcctatat cgatgtcaaa aatcttgccc
    78421 atcgtatcca aggtgaggtt aagatgatta cgggcttgga cgacgatgtt tgctatccca
    78481 ttacccagtt tgcgatttat aatcgtctga cctgcgataa aacctatcgc atcatgcctg
    78541 agtatgctca cgaagccatg aatgtatttg tcaatgacca agtctacaac tggctctgtg
    78601 gaagtgagat tccttttaaa tatctaaaat aaggagtcga ctctaagcac aaaatcttaa
    78661 aaattacaaa cacgcatagt atcaggggat taaaaaaact tgatactatg cgttttatca
    78721 tggaaatata gtaaaatgaa acaagaatag gacaaaacga tcaggacagt caaatcgatt
    78781 tctaacaatg ttttagaagc aaatgtgtac tattctagtt tcaatctatt atatttatag
    78841 aattttttgt tgctagattt gtcaaattgc ttaaaataat ttttttcaga aagcaaaagc
    78901 cgatacctat cgagtagggt agttcttgct atcgtcaggc ttgtctgtag gtgttaatac
    78961 ttttcaaaaa tctctttaaa ccacgtcagc ttcgccttgc cgtatatatg ttactgactt
    79021 cgtcagttct atctgccacc tcaaaacggt gttttgagct gacttcgtca gttctatctg
    79081 ccacctcaaa acggtgtttt gagctgactt tgtcagtctt atctacaacc tcaaaacagt
    79141 gttttgagca tcatgcggct agcttcttag tttgctcttt gattttcatt gagtataaaa
    79201 acagatgagt ttctgttttc tttttatgga ctataaatgt tcagctgaaa ctactttcaa
    79261 ggacattatt atataaaaga attttttgaa actaaaatct actatattac actatattga
    79321 aagcgtttta aaaatgaggt ataataaatt tactaacgct tataaaaagt gatagaatct
    79381 atttttatgt atatgtaaag atagattgct gtaaaaatag tagtagctat gcgaaataac
    79441 agatagagag aagggattga agcttagaaa aggggaataa tatgatattt aaggcattca
    79501 agacaaaaaa gcagagaaaa agacaagttg aactactttt gacagttttt ttcgacagtt
    79561 ttctgattga tttatttctt cacttatttg ggattgtccc ctttaagctg gataagattc
    79621 tgattgtgag cttgattata tttcccatta tttctacaag tatttatgct tatgaaaagc
    79681 tatttgaaaa agtgttcgat aaggattgag caggaagtat ggtgtaaata gcataggctg
    79741 atgtccatca tttgcttata aagagatatt ttagtttaat tgcagcggtg tcctggtaga
    79801 taaactagat tggcaggagt ctgattggag aaaggagagg ggaaaattgg caccaatttg
    79861 agatagtttg tttagttcat ttttgtcatt taaatgaact gtagtaaaag aaagttaata
    79921 aaagacaaac taagtgcatt ttctggagta aatgtcttat ttcagaaatc gggatataga
    79981 tatagagagg atcagtatga atcggagtgt tcaagaacgt aagtgtcgtt atagcattag
    80041 gaaactatcg gtaggagcgg tttctatgat tgtaggagca gtggtatttg gaacgtctcc
    80101 tgttttagct caagaagggg caagtgagca acctctggca aatgaaactc aactttcggg
    80161 ggagagctca accctaactg atacagaaaa gagccagcct tcttcagaga ctgaactttc
    80221 tggcaataat caagaacaag aaaggaaaga taagcaagaa gaaaaaattc caagagatta
    80281 ctatgcacga gatttggaaa atgtcgaaac agtgatagaa aaagaagatg ttgaaaccaa
    80341 tgcttcaaat ggtcagagag ttgatttatc aagtgaacta gataaactaa agaaacttga
    80401 aaacgcaaca gttcacatgg agtttaagcc agatgccaag gctccagcat tctataatct
    80461 cttttctgtg tcaagtgcta ctaaaaaaga tgagtacttc actatggcag tttacaataa
    80521 tactgctact ctagaggggc gtggttcgga tgggaaacag ttttacaata attacaacga
    80581 tgcaccctta aaagttaaac caggtcagtg gaattctgtg actttcacag ttgaaaaacc
    80641 gacagcagaa ttgccaaatg gtcgagttcg cctgtatgtt aatggtgttt tatctcgaac
    80701 aagtctgaaa tctggcaatt tcattaaaga tatgccagat gtaacgcatg tgcaaatcgg
    80761 agcaaccaag cgtgccaaca atacggtttg ggggtcaaat ctacagattc ggaatctcac
    80821 tgtgtataat cgtgctttaa caccagaaga ggtacaaaaa cgtagtcaac tttttaaacg
    80881 ctcagattta gaaaaaaaac tacctgaagg agcggcttta acagagaaaa cggacatatt
    80941 cgaaagcggg cgtaacggta aaccaaataa agatggaatc aagagttatc gtattccagc
    81001 acttctcaag acagataaag gaactttgat cgcaggtgca gatgaacgcc gtctccattc
    81061 gagtgactgg ggtgatatcg gtatggtcat cagacgtagt gaagataatg gtaaaacttg
    81121 gggtgaccga gtaaccatta ccaacttacg tgacaatcca aaagcttctg acccatcgat
    81181 cggttcacca gtgaatatcg atatggtgtt ggttcaagat cctgaaacca aacgaatctt
    81241 ttctatctat gacatgttcc cagaagggaa gggaatcttt ggaatgtctt cacaaaaaga
    81301 agaagcctac aaaaaaatcg atggaaaaac ctatcaaatc ctctatcgtg aaggagaaaa
    81361 gggagcttat accattcgag aaaatggtac tgtctataca ccagatggta aggcgacaga
    81421 ctatcgcgtt gttgtagatc ctgttaaacc agcctatagc gacaagggtg atctatacaa
    81481 gggtaaccaa ttactaggca atatctactt cacaacaaac aaaacttctc catttagaat
    81541 tgccaaggat agctatctat ggatgtccta cagtgatgac gacgggaaga catggtcagc
    81601 tcctcaagat attactccga tggtcaaagc cgattggatg aaattcttgg gtgtaggtcc
    81661 tggaacagga attgtacttc ggaatgggcc tcacaaggga cggattttga taccggttta
    81721 tacgactaat aatgtatctc acttaaatgg ctcgcaatct tctcgtgtca tctattcaga
    81781 tgatcatgga aaaacttggc atgctggaga agcggtcaac gataaccgtc aggtagacgg
    81841 tcaaaagatc cactcttcta cgatgaacaa taaacgtgcg caaaatacag aatcaacggt
    81901 ggtacaacta aacaatggag atgttaaact ctttatgcgt ggtttgactg gagatcttca
    81961 ggttgctaca agtaaagacg gaggagtgac ttgggagaag gatatcaaac gttatccaca
    82021 ggttaaagat gtctatgttc aaatgtctgc tatccatacg atgcataatg gaaaagaata
    82081 cattatcctc agcaatgcag gtggaccgaa tcgtgaaaat gggatggtcc acttggcacg
    82141 tgtcgaagaa aatggtgagt tgacttggct caaacacaat ccaattcaaa aaggagagtt
    82201 tgcctataat tcgctccaag aattaggaaa tggggagtat ggcatcttgt atgaacatac
    82261 tgaaaaagga caaaatgcct ataccctatc atttagaaaa tttaattggg aatttttgag
    82321 caaagatctg atttctccta ccgaagcgaa agtgaagcga actagagaga tgggcaaagg
    82381 agagatgggc aaaggagtta ttggcttgga gtttgactca gaagtattgg tcaacaaggc
    82441 tccaaccctt caattggcaa atggtaaaac agcgactttc ctaacccagt atgatagcaa
    82501 aaccttgttg tttgcagtag ataaggaaga tatcggacag gaaattattg gtatagctaa
    82561 aggaagcatc gaaagtatgc ataatcttcc tgtaaatcta gcaggtgcca gagttcctgg
    82621 cggagtaaat ggtagcaaag cagcggtgca tgaagttcca gaatttacag ggggagttaa
    82681 tggtacagag ccagctgttc atgaaatcgc agagtataag ggatctgatt cgcttgtaac
    82741 tcttactaca aaagaagatt atacttacaa agctcctctt gctcagcagg cacttcctga
    82801 aacaggaaac aaggagagtg acctcctagc ttcactagga ctaacagctt tcttccttgg
    82861 tctgtttacg ctagggaaaa agagagaaca ataagagaag aattctaaac atttgatttt
    82921 gtaaaaatag aaggagatag caggttttca agcctgctat ctttttttga tgacattcaa
    82981 gctgatacga aatcataaga ggtctgaaac tactttcaga gtagtctgtt ctataaaata
    83041 tagta
//
LOCUS       DBEJNA010000005        67436 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEJNA010000005 DBEJNA010000000
VERSION     DBEJNA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 67436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.05"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..706
                     /locus_tag="ACL3JB_000365"
                     /pseudo
     CDS             1..706
                     /locus_tag="ACL3JB_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            1162..2340
                     /locus_tag="ACL3JB_000366"
     CDS             1162..2340
                     /locus_tag="ACL3JB_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGR0685168.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQIFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYIAESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            2654..2785
                     /locus_tag="ACL3JB_000367"
     CDS             2654..2785
                     /locus_tag="ACL3JB_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0685169.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2806..4356
                     /gene="dltA"
                     /locus_tag="ACL3JB_000368"
     CDS             2806..4356
                     /gene="dltA"
                     /locus_tag="ACL3JB_000368"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0685170.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            4353..5597
                     /gene="dltB"
                     /locus_tag="ACL3JB_000369"
     CDS             4353..5597
                     /gene="dltB"
                     /locus_tag="ACL3JB_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0685171.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5611..5850
                     /gene="dltC"
                     /locus_tag="ACL3JB_000370"
     CDS             5611..5850
                     /gene="dltC"
                     /locus_tag="ACL3JB_000370"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0685172.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5843..7111
                     /gene="dltD"
                     /locus_tag="ACL3JB_000371"
     CDS             5843..7111
                     /gene="dltD"
                     /locus_tag="ACL3JB_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0685173.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            7266..7706
                     /gene="adcR"
                     /locus_tag="ACL3JB_000372"
     CDS             7266..7706
                     /gene="adcR"
                     /locus_tag="ACL3JB_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0685174.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7706..8410
                     /locus_tag="ACL3JB_000373"
     CDS             7706..8410
                     /locus_tag="ACL3JB_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0685175.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            8403..9209
                     /locus_tag="ACL3JB_000374"
     CDS             8403..9209
                     /locus_tag="ACL3JB_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0685176.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            9219..10724
                     /gene="adcA"
                     /locus_tag="ACL3JB_000375"
     CDS             9219..10724
                     /gene="adcA"
                     /locus_tag="ACL3JB_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0685177.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11884..12657)
                     /locus_tag="ACL3JB_000376"
     CDS             complement(11884..12657)
                     /locus_tag="ACL3JB_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0685178.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNQKLLDAVELFDGEWVSDIQ"
     gene            12833..14236
                     /locus_tag="ACL3JB_000377"
     CDS             12833..14236
                     /locus_tag="ACL3JB_000377"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0685179.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            14351..14989
                     /locus_tag="ACL3JB_000378"
     CDS             14351..14989
                     /locus_tag="ACL3JB_000378"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0685180.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            15001..15441
                     /locus_tag="ACL3JB_000379"
     CDS             15001..15441
                     /locus_tag="ACL3JB_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0685181.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            15434..15865
                     /locus_tag="ACL3JB_000380"
     CDS             15434..15865
                     /locus_tag="ACL3JB_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0685182.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15856..16326
                     /locus_tag="ACL3JB_000381"
     CDS             15856..16326
                     /locus_tag="ACL3JB_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0685183.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            16351..17124
                     /locus_tag="ACL3JB_000382"
     CDS             16351..17124
                     /locus_tag="ACL3JB_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0685184.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            17121..17921
                     /locus_tag="ACL3JB_000383"
     CDS             17121..17921
                     /locus_tag="ACL3JB_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0685185.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17980..20274
                     /locus_tag="ACL3JB_000384"
     CDS             17980..20274
                     /locus_tag="ACL3JB_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0685186.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            20284..23400
                     /locus_tag="ACL3JB_000385"
     CDS             20284..23400
                     /locus_tag="ACL3JB_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0685187.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            23483..25249
                     /locus_tag="ACL3JB_000386"
     CDS             23483..25249
                     /locus_tag="ACL3JB_000386"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0685188.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            25395..26546
                     /locus_tag="ACL3JB_000387"
     CDS             25395..26546
                     /locus_tag="ACL3JB_000387"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0685189.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            26691..27575
                     /locus_tag="ACL3JB_000388"
     CDS             26691..27575
                     /locus_tag="ACL3JB_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0685190.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(27612..27770)
                     /locus_tag="ACL3JB_000389"
     CDS             complement(27612..27770)
                     /locus_tag="ACL3JB_000389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685191.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            27974..28225
                     /locus_tag="ACL3JB_000390"
     CDS             27974..28225
                     /locus_tag="ACL3JB_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0685192.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            28213..28503
                     /locus_tag="ACL3JB_000391"
     CDS             28213..28503
                     /locus_tag="ACL3JB_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0685193.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(28707..28814)
                     /locus_tag="ACL3JB_000392"
                     /pseudo
     CDS             complement(28707..28814)
                     /locus_tag="ACL3JB_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(28909..30240)
                     /locus_tag="ACL3JB_000393"
     CDS             complement(28909..30240)
                     /locus_tag="ACL3JB_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0685194.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(30262..31773)
                     /locus_tag="ACL3JB_000394"
     CDS             complement(30262..31773)
                     /locus_tag="ACL3JB_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0685195.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(31984..32931)
                     /gene="arcC"
                     /locus_tag="ACL3JB_000395"
     CDS             complement(31984..32931)
                     /gene="arcC"
                     /locus_tag="ACL3JB_000395"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0685196.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(33096..34112)
                     /gene="argF"
                     /locus_tag="ACL3JB_000396"
     CDS             complement(33096..34112)
                     /gene="argF"
                     /locus_tag="ACL3JB_000396"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0685197.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(34170..35399)
                     /gene="arcA"
                     /locus_tag="ACL3JB_000397"
     CDS             complement(34170..35399)
                     /gene="arcA"
                     /locus_tag="ACL3JB_000397"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0685198.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            36155..37834
                     /locus_tag="ACL3JB_000398"
     CDS             36155..37834
                     /locus_tag="ACL3JB_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0685199.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQYGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(37874..39958)
                     /locus_tag="ACL3JB_000399"
     CDS             complement(37874..39958)
                     /locus_tag="ACL3JB_000399"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0685200.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            40129..41409
                     /locus_tag="ACL3JB_000400"
     CDS             40129..41409
                     /locus_tag="ACL3JB_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0685201.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            41500..44145
                     /locus_tag="ACL3JB_000401"
     CDS             41500..44145
                     /locus_tag="ACL3JB_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0685202.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTILVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTELIKKEEI"
     gene            44229..45098
                     /locus_tag="ACL3JB_000402"
     CDS             44229..45098
                     /locus_tag="ACL3JB_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0685203.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILNKTSIPTPESLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQIPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGQTDWDGRKIYQEAAAGNAICQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEENQW"
     gene            45092..46972
                     /locus_tag="ACL3JB_000403"
     CDS             45092..46972
                     /locus_tag="ACL3JB_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0685204.1"
                     /translation="MVRFTGLSSKQAQAIEVLKNHISLPDVEVAVTQSDQASISIKGE
                     GGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            47298..47615
                     /locus_tag="ACL3JB_000404"
                     /pseudo
     CDS             47298..47615
                     /locus_tag="ACL3JB_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(47676..48489)
                     /locus_tag="ACL3JB_000405"
                     /pseudo
     CDS             complement(47676..48489)
                     /locus_tag="ACL3JB_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(48434..48616)
                     /locus_tag="ACL3JB_000406"
     CDS             complement(48434..48616)
                     /locus_tag="ACL3JB_000406"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0685205.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDPYQRVNRLPAKL"
     gene            48951..50576
                     /locus_tag="ACL3JB_000407"
     CDS             48951..50576
                     /locus_tag="ACL3JB_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HGR0685206.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTV
                     SGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(51068..51217)
                     /gene="rpmG"
                     /locus_tag="ACL3JB_000408"
     CDS             complement(51068..51217)
                     /gene="rpmG"
                     /locus_tag="ACL3JB_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0685207.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(51233..51415)
                     /gene="rpmF"
                     /locus_tag="ACL3JB_000409"
     CDS             complement(51233..51415)
                     /gene="rpmF"
                     /locus_tag="ACL3JB_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0685208.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(51567..51767)
                     /locus_tag="ACL3JB_000410"
     CDS             complement(51567..51767)
                     /locus_tag="ACL3JB_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0685209.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(51770..52777)
                     /locus_tag="ACL3JB_000411"
     CDS             complement(51770..52777)
                     /locus_tag="ACL3JB_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0685210.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            52969..54999
                     /locus_tag="ACL3JB_000412"
     CDS             52969..54999
                     /locus_tag="ACL3JB_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0685211.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            55003..55287
                     /locus_tag="ACL3JB_000413"
     CDS             55003..55287
                     /locus_tag="ACL3JB_000413"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0685212.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            55300..56646
                     /locus_tag="ACL3JB_000414"
     CDS             55300..56646
                     /locus_tag="ACL3JB_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0685213.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            56650..57507
                     /locus_tag="ACL3JB_000415"
     CDS             56650..57507
                     /locus_tag="ACL3JB_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0685214.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            57504..58436
                     /locus_tag="ACL3JB_000416"
     CDS             57504..58436
                     /locus_tag="ACL3JB_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0685215.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            58669..60372
                     /gene="ilvD"
                     /locus_tag="ACL3JB_000417"
     CDS             58669..60372
                     /gene="ilvD"
                     /locus_tag="ACL3JB_000417"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0685216.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(60398..60562)
                     /locus_tag="ACL3JB_000418"
     CDS             complement(60398..60562)
                     /locus_tag="ACL3JB_000418"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685217.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSPKHCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(60626..60967)
                     /locus_tag="ACL3JB_000419"
     CDS             complement(60626..60967)
                     /locus_tag="ACL3JB_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0685218.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            61091..61942
                     /gene="rgg"
                     /locus_tag="ACL3JB_000420"
     CDS             61091..61942
                     /gene="rgg"
                     /locus_tag="ACL3JB_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0685219.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            62133..63380
                     /locus_tag="ACL3JB_000421"
     CDS             62133..63380
                     /locus_tag="ACL3JB_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR0685220.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKFSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            63458..64747
                     /gene="hisS"
                     /locus_tag="ACL3JB_000422"
     CDS             63458..64747
                     /gene="hisS"
                     /locus_tag="ACL3JB_000422"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0685221.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            64890..65354
                     /locus_tag="ACL3JB_000423"
     CDS             64890..65354
                     /locus_tag="ACL3JB_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685222.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTILVKKKKMCYNVSKLRE
                     KRKGAMMWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAAMSRLLQEMIGKE
                     PIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            65364..65570
                     /locus_tag="ACL3JB_000424"
     CDS             65364..65570
                     /locus_tag="ACL3JB_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685223.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            65570..65767
                     /locus_tag="ACL3JB_000425"
     CDS             65570..65767
                     /locus_tag="ACL3JB_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685224.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            65770..66504
                     /locus_tag="ACL3JB_000426"
     CDS             65770..66504
                     /locus_tag="ACL3JB_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0685225.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            66516..67157
                     /locus_tag="ACL3JB_000427"
     CDS             66516..67157
                     /locus_tag="ACL3JB_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0685226.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLGVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            67175..67405
                     /locus_tag="ACL3JB_000428"
     CDS             67175..67405
                     /locus_tag="ACL3JB_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685227.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT        20423 a        11943 c        14451 g        20619 t
ORIGIN      
        1 ggaatgacta tcgaagagat ggataattat ctcagacaaa actggcgctt gactaaggaa
       61 ctgataaaac agagaaaata taagcctcaa ccagttctta aagttgagat acctaaacca
      121 gacggaggca gcctctaagc gtgtgatgta ttcagtcagt cgttttattg agaaacggct
      181 aggtttgaaa gtaaacatga ccaagactaa gattaccaga ccaagagagt tgaaatatct
      241 aggttttggg ttctggaaat catcagatgg ttggaaaagc cgtccacatc aagatagtgt
      301 tcggagattt aagtttaaat tgaagaaact aacacagagg aaatggagta tagacctaac
      361 aagacgtatt gagcaactga atttgtctat tcgaggatgg ataaactatt tctcattggg
      421 aaatatgaaa agtatagtcg ccagcataga tgagcgcttg cgtactcgcc tacgagtgat
      481 tatctggaag caatggaaga agaaatcgag acgattatgg ggattgctta agttaggagt
      541 tcctaaatgg atagcagata aggtatctgg ctggggcgac cattatcaat tagtagctca
      601 gaagtcggta cttaaacgtg ctatatcaaa accagtcctg gaaaaacgtg gactggtttc
      661 gtgtttggat tattaccttg aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg
      721 aacggcacgt acggtggtgt gagaggggct agagattatc ccctactcga ttaactcccc
      781 tgaaatttat tttaattatg caaatttcac gtatttttga tgctgagacg acgatcctgg
      841 gaacttttca gatatttttt tgactatcta aatctatcat tagaaaagct tagagcgcca
      901 aaggatttga gcgtttttct gatttttaag actttttcca gtctcttttt cgattgaaga
      961 tgtaattatt ctactaacta actaacttct tagtactagc caacaacgat aatcataatt
     1021 cctcctaaaa ttaggaataa taaaggcaat agtttttgtt ttttcatgta aaaaacctca
     1081 cttttgtttt ctgctatttt atgctaaaat attaaaaatc aaatttaatt ccaaagtttg
     1141 taactaaagg gggagcgcta catgtctaat tcatttgtca agttgttagt ctctcaatta
     1201 tttgcaaatt tagcagatat tttctttaga gtaacaatca ttgctaacat atacattatt
     1261 tcaaaatcag taattgccac atcactagtt cctatcttaa taggaatatc ctcttttgtt
     1321 gcgagtcttt tagttccgtt ggttactaaa aggttagcgc taaatagggt tttatcttta
     1381 tctcaatttg gaaagactat attattggcg atactggtag gaatgtttac cgtaatgcaa
     1441 tccgtagcgc ctttggtgac ctatctattt gttgttgcaa tttccatact agatggtttt
     1501 gcagcacccg tttcctatgc tattgtgcca cgctatgcga ccgatttggg taaggctaat
     1561 tcagccttat caatgactgg tgaagctgtt caattgatag gttggggatt aggtggactc
     1621 ttgtttgcaa caattggtct gttacctacc acgtttatca ttttagtctt gtatatcatt
     1681 tctagctttc tgatgttatt tcttcctaac gctgaagtgg aggtgttaga gtcagaaact
     1741 aatcttgaaa ttttgctcaa aggttggaag ttagttgcta gaaatcctag attaagactt
     1801 tttgtatcag caaatttatt ggaaattttt tcaaatacga tttgggtttc ttccattata
     1861 cttgtttttg taacggagtt attaaataaa acggaaagtt actggggata ttctaataca
     1921 gcatactcta ttggtattat aattagtggc ttaattgctt ttaggctatc tgaaaagttc
     1981 cttgctgcta aatgggaaag tattcttttt cctcttgtag ctatggcaat agtgacactg
     2041 actattctat attttccaaa cgcacagata tttttattat tttcagcttt agttggtatg
     2101 ttatcgcaac taaaagaagt tcctgaaagt gtatttcttc aggaaacagt agaggaaaat
     2161 catttagtta atgtctattc cgttcttgaa gtgatttcta cattagcatt ttcagtattt
     2221 gttttgctaa tgagctatat tgctgagagt tttggtatta gcatcagttt ttggctatca
     2281 gccatttgtc tgatgataga agctatttta atttatatca gacgagatta ttttaaatga
     2341 gagagtggtt aaaaagtctt taaaaatcag aaaagcgcat agtatcaggt gttgaaaaaa
     2401 cttgatattg tgtgttttat tatgggaaga tttacttcat tgtctcctga aatggagttt
     2461 tgaagcagga tcactctatt tgaaaatata catagaaaaa ctgtataatc cttaaaataa
     2521 gctgaaatct attggaaaca tacggtaaac aattgaaaag atactatata aagtggtaca
     2581 atggtagaaa aataagctag taagaatcac tcttatttta gcgaaaaatt acagaaatga
     2641 atggtttttc ttgatgaaac agagaaaaga attgtacctc tttcttggtc ggacagcctt
     2701 gtattttctt atctttctag ggctgcttta cttctttagc tatcttggtc agggtcaagg
     2761 aagctttatc tataatgaat tttaacttga aggagaatcc ctattgtgtc aaataaacca
     2821 atagcagata tgattgaaac cattgagcat tttgctcaga cacagcctag ctatcctgtc
     2881 tataatgttt tggggcagga acacacttat ggcgatttaa aggctgattc ggatagtttg
     2941 gctgcagtca ttgaccaact aggcttgcct gagaagtctc ctgtggttgt ttttggtggc
     3001 caagaatatg aaatgttggc aacctttgta gcgctgacta agtcaggtca tgcctacatt
     3061 ccaattgata gccattcggc cttggagcga gtttcagcta ttttagaagt agcagagcca
     3121 agcttgatta ttgccatttc agcctttccc ttggagcagg tttctacacc aatgataaat
     3181 ctagctcagg ttcaagaagc ctttgcccaa gggaataact atgaaatcac gcatccagtc
     3241 aagggagatg ataattacta cattatcttt acttctggta cgactggtaa gcctaaggga
     3301 gtgcagattt cacatgataa tctcctcagc tttacaaact ggatgattac ggataaggaa
     3361 tttgcgacac cgagtcgtcc gcaaatgctg gcacagccac cttattcttt tgacttgtct
     3421 gtcatgtatt gggcaccgac cttggcactt ggtggtacgc ttttcactct tccttcagtc
     3481 atcactcagg actttaagca actctttgcg gctatctttt cattgccaat cgctatctgg
     3541 acatcaacac catcctttgc agatatggcc atgttgtctg aatacttcaa cagtgagaaa
     3601 atgcctggaa tcacgcattt ctactttgat ggtgaagaat tgacggtcaa aacagctcaa
     3661 aaactgcgcg agcgtttccc aaatgcccgt atcatcaatg cttacggccc aacagaagcg
     3721 acagtagctc tgtcagcagt tgccgtgaca gacgagatgt tagcgactct caaacgccta
     3781 ccaatcggct ataccaaggc tgattctcca acctttatca ttgacgagga aggaaataaa
     3841 ctgccaaatg gcgaacaggg agaaatcatt gtttctgggc cagctgtttc aaaaggttat
     3901 atgaacaatc ctgaaaaaac agcagaagcc ttctttgagt ttgaaggtct gccagcctat
     3961 cacacaggcg atgtgggaac catgacagat gagggcttgc ttctctacgg cggacgcatg
     4021 gacttccaga ttaagtttaa cggttaccgc attgagttag aagatgtctc tcaaaacctc
     4081 aacaagtctc gctttatcga atctgctgtc gcagtaccgc gctataacaa ggaccacaag
     4141 gtacaaaatc tattggctta tgtcatctta aaagacggtg ttcgtgagca gtttgagcga
     4201 gatatcgata ttaccaaggc catcaaggaa gacctgacag acatcatgat gtcctacatg
     4261 atgccatcta aattccttta ccgagacagt ttgccactga ctccaaatgg aaagattgac
     4321 atcaaaggat tgattaacga ggtgaataag agatgatgga gttttttcaa cagcttcctc
     4381 atttagagcc atatggcaat cctcagtatt ttgtttatgt gattgctgca accttgccca
     4441 tctttatagg cctctttttc aagaaacgct ttgcctggta tgaagtgttg gtaagtctct
     4501 tctttattgt caccatgttg gtgggtggaa agaccaatca actagctgcc ttgggtattt
     4561 acctttgctg ggaaatattg ctcctgcttt tctacaagca ttatcgaaaa agcaaggatg
     4621 gcaagtgggt cttctactta gttagttttc tgtccctact tccgattatc tttgtcaagg
     4681 tgcaaccagc tatcaatgga acgcagtctt tgcttgggtt cttgggaatt tcttacctga
     4741 cctttcgttc ggttgggatt atcatcgagc tgagagatgg agtgattaag gattttaccc
     4801 tctgggaatt cctccgtttc cttctcttca tgccaacttt ctcgagtggt ccaatcgatc
     4861 gttttaagcg atttaatgaa aattatcagg ccattcctga gcgagatgag ttgatggata
     4921 tgctggatga atctgtccgc tatatcatgc ggggcttttt gtataagttt atcctagctc
     4981 atgttttagg agagacctta ctacctcctc tgaagaattt agccttgcag tcaggtggct
     5041 tctttaatct ctatgccttg gcagttatgt atacttttgg tctggagctc ttctttgact
     5101 ttgcaggtta ttctatgttt gctttggcca tctcaaactt gatgggaatc cgtagcccta
     5161 tcaactttaa caagcccttt ttatcaaggg atttaaagga gttttggaat cgctggcata
     5221 tgagtctgtc cttctggttc cgtgactttg tctttatgcg aatggtgatg gtgttaacca
     5281 gaaagaaagt ctttaaaaat cgtaatgtaa cctcaagcat ggcctacatt gtaaatatgc
     5341 tgattatggg attttggcat ggtgtgacct ggtactatat cgcctatgga ctctttcatg
     5401 gactaggctt ggtcatcaat gatgcctggg ttcgcaagaa aaaaacgctc aataaggaac
     5461 ggaaaaaagc agggaaggct gccctacctg agaatcgctg gattcagttg cttggcatgg
     5521 ttgtcacttt ccatgttgtc atgttgtcat tcttaatctt ttctggattc ttgaataatc
     5581 tatggtttaa aaaataaaag gaaataaaat atggatatca aatcagaagt tattgaaatt
     5641 attgatgagt tgtttatgga agatgtttct gacatgatgg atgaagatct ttttgatgca
     5701 ggtgtcttgg atagtatggg aacggttgag ttgattgtgg agattgagaa ccgttttgac
     5761 attcgtgtcc ctgtaacaga gtttggtcgt gacgactgga atacagctaa taaaatcata
     5821 gctggtattg tggagctaca aaatgcttaa acgcttatgg atgatcttcg gaccggtctt
     5881 gatcgctggt ttgttggttt ttctgctcat tttcttttat cctactgaga tgcatcataa
     5941 tctaggagct gaaaagcgtt cagcagtggc tactactatc gatagtttta aggagcgaag
     6001 tcaaaaagtc agagcactat ctgatccaaa tgtgcgtttt gttcccttct ttggctctag
     6061 tgaatggctt cgttttgacg gtgctcatcc tgcggtatta gctgagaaat acaatcgttc
     6121 ctaccgtcct tatcttttag gacagggggg agctgcatcg cttaaccaat attttggaat
     6181 gcaacagatg ttaccacagc tggagaataa acaagttgtg tatgttatct cacctcagtg
     6241 gttcagtaaa aatggctatg atccagcagc cttccagcag tattttaatg gagaccagtt
     6301 gactagtttt ctgaaacatc aatctgggga tcaggctagt caatatgcag cgactcgctt
     6361 actgcaacag ttcccaaacg tagctatgaa ggacctggtt cagaagttgg caagtaaaga
     6421 agaattgtcg acagcagaca atgaaatgat tgaattattg gctcgtttta atgaacgcca
     6481 agcttccttt tttggtcagt tttcggttag aggctatgtt aactacgata agcatgtagc
     6541 taagtattta aaaatcttgc cagaccagtt ttcttatcag gcaatagaag atgttgtcaa
     6601 agcagatgct gaaaaaaata cttccaataa tgagatggga atggaaaatt atttctataa
     6661 tgagcagatc aagaaggatt tgaagaaatt aaaggattct cagaaaagct ttacctatct
     6721 caagtcgcca gagtataatg acttgcagtt ggttttaaca cagttttcta aatctaaggt
     6781 aaacccgatt tttatcattc cacctgttaa taaaaaatgg atggactatg ctggtctacg
     6841 agaggatatg taccaacaaa cggtgcagaa gattcgctac cagttagaaa gtcaaggttt
     6901 taccaatata gcagattttt ctaaggacgg cggggagcct ttctttatga aggacaccat
     6961 tcaccttggt tggttgggtt ggttggcttt tgacaaggca gttgatcctt tcctatccaa
     7021 tcccacacca gctccgactt accatctgaa tgagcgcttt ttcagcaaag attgggcgac
     7081 ttatgatgga gatgtcaaag aatttcaata gataatataa tatagaagag ttcaagaatg
     7141 aaactagttt tcacgttttt tcttgactct ttttttgctt gtgatataat taactggtaa
     7201 acaaaatgtc aaagaatagt atttttctct taaaaaagag aagtctaaaa ggaaaggagt
     7261 cagatatgag acagctagca aaggatatca atgctttttt gaatgaggtg attttgcagg
     7321 cggaaaatca gcatgaaatc ctaataggtc attgcactag cgaggtggcc ctgaccaata
     7381 ctcaggagca tatccttatg ctcttgtcag aggaatcttt aacaaattca gaattggccc
     7441 gtcgtctcaa tgtcagtcag gcggcagtta ccaaggccat taagtctttg gtcaaggaag
     7501 ggatgttgga aacatctaaa gattctaaag atgcgcgtgt gattttttat cagttgactg
     7561 acttggctcg tccaatcgct gaggagcacc accatcacca tgagcataca cttttaacct
     7621 atgaacaagt ggcgactcag tttactccaa atgaacaaaa agtgattcag cggtttttga
     7681 ctgctttagt aggagaaatc aaataatgag atatattacg gtagaggatt tgtccttcta
     7741 ttatgataag gagcctgttc ttgaacatat caattatagt gttgatagtg gggaatttgt
     7801 taccttgact ggggaaaatg gagcggctaa gacgacgctc atcaaggcta gtcttggaat
     7861 tctgcaacca cgcattggaa aggtggctat ttcaaagaca aatacgcaag gtaagaaatt
     7921 gagaatagcc tatcttcctc aacaaattgc cagttttaat gctggttttc caagtacggt
     7981 ctatgaattt gtcaagtcgg gtcgctatcc gagaaaaggc tggttccgtc gtttgaatgc
     8041 tcatgatgag gagcatatca aggctagtct ggactcagtt ggcatgtggg aacatcgaga
     8101 caaacgcttg gggtctctat ctgggggaca aaagcagcga gcggtgattg cgcgtatgtt
     8161 tgcttctgac cctgatgtgt ttatcctaga cgagccgaca acggggatgg atgcaggaag
     8221 taaaaatgaa ttttacgaac tcatgcacca cagcgcccat catcatggca aggctgtttt
     8281 gatgattacc catgaccctg aagaagttaa ggattatgcg gatcgcaata ttcatctagt
     8341 ccgtaaccaa gactcgccat ggcgttgttt caatgttcat gagaatggcc aggaggtggg
     8401 ccatgcttag tttattatct tacgacttta tacaacgcgc ctttttggcg gttattgcta
     8461 tgagtctttt ctcaccggta ttgggaacct tcctcatctt gcgtcgtcag agtttgatga
     8521 gtgataccct tagccacgtc tcactttcag gtgtagcctt tggtctggtt ttggggattt
     8581 ctccaactgt ttctactatt gccattgtct tgattgcggc ggtctttctg gagtatctcc
     8641 gtacggttta caagagcttt atggaaatcg ggacagctat cctcatgtca acaggtctgg
     8701 ctgtttctct gattgtcatg agcaagggta aaagctcgag ttcaatgagt ttggaccaat
     8761 atctctttgg ttcgatcgtg actatcagtg aagaacaggt catttccctc tttgtcattg
     8821 cggcggttgt tttgattttg acctttctct ttcttcgtcc tatgtatatc ttaacttttg
     8881 acgaagatac ggcctttgtg gatggcttgc cagttcgtac catgtccatt ctttttaaca
     8941 tggtgacagg ggtggctatt gcccttatga ttcctgcagc aggagctctt ctggtatcga
     9001 ccattatggt cttgccagct agtattgccc tgcgtctggg gaaaaacttt aaatcggtta
     9061 tgctgcttgc cagtgcgatt ggctttttgg gaatggtagc aggactttac atttcctact
     9121 atgcagaaac acctgcaagt gcaagtatta ccattatttt tgtaactgtc tttatactaa
     9181 tcagtttagt aagacgtttt atcaaatagg agacgaacgt gaaaaaaatt agcttattac
     9241 tagccagtct atgtgccttg tttttagtgg cttgttccaa tcaaaaacag gcagatggta
     9301 aactcaatat cgtgacaacc ttttaccctg tctatgaatt taccaagcaa gttgcaggag
     9361 atacggctaa tgtagaactc ctaatcggtg ctgggacaga acctcatgaa tacgaaccat
     9421 ctgccaaggc agttgccaaa atccaagatg cagatacctt cgtttatgaa aatgaaaaca
     9481 tggaaacatg ggtacctaaa ttgctagata ccttggataa gaaaaaagtg aaaaccatca
     9541 aggcgacagg cgatatgttg ctcttgccag gtggcgagga agaagaggga gaccatgacc
     9601 atggagaaga aggtcatcac catgagtttg acccccatgt ttggttatca ccagttcgtg
     9661 ccattaaact agtagagcac attcgtgaca gcttgtcagc agattatcct gataaaaaag
     9721 agacctttga gaagaatgca gctgcctata tcgaaaaatt gcaagccttg gataaggctt
     9781 acgcagaagg cttgtctcaa gcaaaacaaa agagctttgt gactcaacac gcagccttta
     9841 actatcttgc cttggactat ggactcaaac aagtcgcaat ctcaggactt tctccagatg
     9901 cagagccatc agctgctcgc ttggcagaat tgacagagta tgtcaagaaa aataaaatcg
     9961 cctatatcta ttttgaagaa aatgcctcac aagcccttgc taacacactt tcaaaagaag
    10021 caggtgtcaa aactgatgtc ctcaatcctt tagaaagtct gacagaagag gacaccaagg
    10081 ctggagaaaa ctacatttcc gtgatggaga aaaacctcaa ggctttgaaa caaacaacag
    10141 accaagaagg cccagcaatc gaacctgaaa aggcagagga taccaagaca gtccaaaatg
    10201 gttacttcga ggatgcagct gtcaaggacc gcaccttgag tgactatgca ggtaactggc
    10261 aatcagttta tcctttcctt gaagacggca cgtttgacca agtctttgac tacaaggcta
    10321 agttgactgg taagatgacc caggctgagt acaaggctta ctatacaaaa ggctatcaga
    10381 cagatgtgac taagattaac attactgata atactatgga atttgttcaa ggtggacaaa
    10441 gcaagaaata cacttacaag tatgtcggta agaaaatttt gacttacaag aaaggcaatc
    10501 gtggcgtgcg ttttctcttt gaagccacag atgctgacgc tggacaattc aagtatgttc
    10561 agtttagtga ccacaatgtt gccccagtta aggcagaaca tttccatatc ttctttggag
    10621 gcacaagcca agaagccctc tttgaagaaa tggacaactg gccaacctac tacccagata
    10681 acctatctgg ccaagaaatc gcccaagaaa tgttggcgca ttgatgagaa atcgactagt
    10741 tcataagagc tagtcggttt tttgatacta gatggctaac ttcattatag acctttcaga
    10801 actttaaaca ataaataaaa ctcttgaaat atctgggctt atatgctaga atgtagttag
    10861 tgtataaggt tcattagaac accaaagccc ctaactagtg ccatagttaa gggctttttt
    10921 gacgtatctt agcgatttaa cgggtgttta taggctagtc attcggtcta cttcttacca
    10981 tctagccatt tgcagacgaa atacaagata attccagcta taacatctgc tataatagta
    11041 agagcaagct ctggtataag gctcattagt ttcacctcct ctcacgaacc gtaaggaacg
    11101 taatcggtaa ccgatgacaa aaatagtata tcacactaca ttcaggtcat caaccttact
    11161 taatgcttga actattgtag attatatgct agaatgtagt taattgataa ggttcattag
    11221 aacaccaaag cccctaacta tggccgtagt taagggcttt tttgacgtat cttagcgatt
    11281 taacgggtgt ttataggcta gtcagtcggt ctactcctta ctatctagcc atctgcagac
    11341 gaaatacaag ataattccag ctataacatc cgctataata gtaagagcga gctctatgat
    11401 aaggctcatt agtttcacct cctctcacga acccatagga acgtaatcgg taaccgatga
    11461 caaaaatagt ataccacaat acatttagat catcaaggtc acttaattct tgaaatatca
    11521 gatctaagag aaaaatcttt aaaatcagaa aaacgcataa tatcaggtgt gcaaaaactt
    11581 gatactatgc gttttattgt gggaaggttt actccatttt ctcctgaaat tgagtttttg
    11641 tccagcctct gtttttaggg ttgctaagaa aataatgtca tgtggtgaat atttgtaaat
    11701 cagtcagcag acagaacgat actcttcgaa aatctcttca catcatgtca gctttgtctt
    11761 tccgtatata tgtgactgac ttcatcagtt ctatctacaa cctcaaaaca gtgtttcgag
    11821 ctgacttcat cagttttcaa atctgtactg tgagcaagct gagactagct tcctatttga
    11881 tttttattga atatcagaaa cccattctcc atcaaataat tcgactgcgt ctaataattt
    11941 ttgatttggc aaggtgtcag aaataaaggt tgtgtatttg gagaggggat taattttaaa
    12001 aaatccagtc ttgtaaaatt tagaactatc aatcagtaag atggtttcat gggctttgtc
    12061 aataatattc ttttttgaaa tagcttggct gagagaagct tcataaacat attggtcatc
    12121 aatacctctt gctgaacaaa atgctaaatc gatattaaaa tgatctaata aagaattttc
    12181 cttatcatag ttgaccacgg aacaggattg atgtttgacc tcgccagatg tgataaagat
    12241 tttggagcta tctttaacag tttcagatag ggtttgtgca gtatgtaaac catttgtaaa
    12301 aataatcaaa ttatcaagtt cagaaagata gggacaaagt tcgtagacag tagtactaga
    12361 atctagatag atacacatac cagaccgaat aaagtcttta gcgagactag cgattagtct
    12421 tttttgccta gtactttctc cttcccgtat ttgatgagaa agttcaattg tgttcataga
    12481 ggacagggtc acgtatccgt gctttctttt gataagacct tgattttcta agaaaattaa
    12541 atcacgacgt aaggtacttg tgctggagaa agtgatttct gccagctctt ttacggcaat
    12601 tctttttttc tttttgatga tttcaatcaa ttcaagtaca cgttcatctt ttatcataag
    12661 ctcctcctaa tttatcattt caactatatt atagcacaaa ttggaggaat gtgaattatt
    12721 tttatgaata ttgggttaac atttgaacat tattcaagta agcgttcaca tattgaaaaa
    12781 ataaaacgtg gggattataa taaagttaat caaggacgaa gagagaagaa aaatggaagc
    12841 ggttttagca atagatttag gtgcgacttc tggaagagca atcgttggtt acctttctga
    12901 aaataaacta gtaatggaag aaataaatcg cttttctaat ctacctatta gagtaaaagg
    12961 gcatttatct tgggatgttg actttctact agctaaaatt cttgaaagta tccgcttggc
    13021 taatactagt tacaagattt tatctatcgg tattgacaca tggggagttg attttggact
    13081 gattgataat gaaggtaagc tgttatcaca acctgttcat tatcgtgatg aaagaacaaa
    13141 gggagtgtta aaggaaatat ctgaaatgac tgaattagaa aaactgtatt cagagacagg
    13201 aaatcagatt atggagataa ataccttgtt tcaactcttt aaggcacgtc aagaatctcc
    13261 tgactctttc tataagacca ataagattct tttaatgcca gatttgttta attatctctt
    13321 gacaggtaag tttgctacag aaaaaagcat tgcttcaaca actcaattat ttgatcctag
    13381 gagtcaaaac tggaatcaga atatcttaaa actatttgaa ttggattcat ctttacttcc
    13441 tgagattgtt tcagagggaa atgttcttgg aaggataaaa aaggagtatg gtttaggcga
    13501 tattcctgtt gtgaatgttt gtagtcatga tacagcaagt gcgattgtct cagtacctaa
    13561 gacagaaggt agtttattta tttcatcagg tacttggtct ttggttggag tggaacttac
    13621 ttcaccgatt cttactaccg aatccttcag ttatggattt acaaatgaag tcggtaaaga
    13681 tggagagatt acatttctga agaattgtac agggttgtgg atcatagagg aactaagacg
    13741 ttcatttgaa cgaagaggga aagcctattc ttttgatgat attaggacaa tggtggagaa
    13801 agaaaaagaa aatcttcctc tgattgatac tgaatcaaca gaatttgcaa cagaatctga
    13861 tatgcacaag actttgacag aatatctagc ttatcatcat gaaactagag agtggacaga
    13921 tggacaacta tttaagattg tttatgaaag cctagctgaa acgtatagga aagcgataga
    13981 gttattagaa gaactaactc ataaggttta taagaggata tatgtgattg gaggaggtgc
    14041 tagagccagt tactttaacc aaatgattgc tgatagaact ggtaaagagg ttcttacagg
    14101 ttcgactgag ggtacagctg tggggaatat tgttgtgcag ctcatagcta tgggacaatt
    14161 aaaagggatg gaagaagctc accatgttat tgaggagttt ctacaattag agagttatta
    14221 ctcccaaaag aattaaaaag attgagagtt tgtaaatttg cctccctccc ccttcttaag
    14281 ttttgtacaa gaagggggga taattggtga attgaaaaat atttagtgtt ttgatatgag
    14341 gaggacaaga atgtcagatg taaaacaaga attaattaag tatggcaaga agctagtaga
    14401 aacagatttg acgaaaggaa caggtgggaa tctcagtgtt ttcgatcgtg aaaaacaatt
    14461 gatggcaatt accccgtcgg gtattgattt ctttgaaatc aaagaatccg atattgtagt
    14521 gatggatatt aatggaaatg ttgtagaggg agaacgcttg ccatctagcg aatggtatat
    14581 gcatttgatt caatatcaaa ctcgtgatga tatcgatgca attatccatg ctcatacaac
    14641 ttatgcaaca gtattagctt gtctcagaga accacttccg gctagtcatt atatgattgc
    14701 agtggcaggg aaagatgttc gggtagctga gtatgcaaca tatggtacga aagaattggc
    14761 tgtgaatgca gctaaagcaa tggaaggtcg tagagcagtt ttactagcga atcatggaat
    14821 tttagcaggt gcacaaaatt tattgaatgc atttaatatt gttgaagaag ttgaatattg
    14881 tgcaaaaatt tattgtttag ctaagaattt tggagagcca gtagttcttc ctgatgagga
    14941 gatggattta atggcagaaa aatttaaaac atacggtcag agaaaatagg gaggatatta
    15001 atgttaaaac atataccgaa aaatatttct ccagatttat tgaagacttt aatggaaatg
    15061 ggacatggag atgaaatagt attagctgac gcgaattatc cttctgcctc atgtgcaaat
    15121 aagctaattc gttgtgatgg cgtaaatatt ccagaattat tagattccat tctgtattta
    15181 atgccattag atagttacgt cgatagttca attcagttta tgaacgttgt ttcgggtgat
    15241 gatattccta agatatgggg tacctataga cagatgattg aaggtcatgg tacagatctt
    15301 aaaacgatta cttatcttag aagagaagac ttttatgaac gtagtaagaa agcttatgct
    15361 attgttgcta caggagaaac ttcactttat gctaatatta tccttaagaa aggagtagtt
    15421 gttgaaagag aaaatgttta atagaggaat tttagttgcc agtcatggta attttgctag
    15481 cggagctctc atgaccgcag aaatgtttgt tggtgagaca acaaatgata gagttaggac
    15541 attaggtttg atgcctggag agaatattgt agagtttgaa cattatttta aaaatcaagt
    15601 aaatgaactg ttagactcaa atcaagaggt tatcgttttg actgacttga ttggaggaag
    15661 tcctaataat gtggctttgt cacggttttt aaatttggat tcagttgata ttgtaacagg
    15721 gtttaatatc cctctcctag tggaattaat atcaagttat gattcaaaaa tcaatttaga
    15781 agaaattgtt caaaatgctc aaaatagttt gtttaatgtt aaacaacaac ttaacgtaga
    15841 ggaggaagag gatttatgtc tatagagttt gttcgtattg atgaccgtct ggtacatggt
    15901 caagttgtca ctacgtggct aaaaaagtat gatattgagc aagttatcat tgttaatgat
    15961 cgcatctcag aagataaaac acgacaatct attttaaaga tttctgcacc ggtaggttta
    16021 aaaattgttt tctttagtgt aaaacggttt gtggaagttt taaactctgt gccaataaaa
    16081 aagagaacaa tgctgatata tacaaatcca aaagatgtgt atgattctat tgaaggaaat
    16141 ttaaaattgg agtacctcaa tgtaggacag atgagtaaaa cggaggaaaa tgaaaaggta
    16201 acgggaggtg tagctctagg tgaagaagac aaatattatt ttaagaaaat agttgataag
    16261 ggaacgagag ttgaaattca aatggttcct aatgataaag ttacaatgtt ggaaaaattt
    16321 ttataaaaat aatttaagga ggtacagtat atgctattca cacaagcatt actggtgaca
    16381 ttagttggga ttattgccac tattgactat aatggaccgt tatttatgat tcaccgtccg
    16441 ttagttacaa gtgcaatggt tggcttagtc ttaggagatt tcacccaagg tgttcttatt
    16501 ggttcagctc ttgaattaac ttggctcggt gtaacaggta ttggaggtta cactccacca
    16561 gatactattt caggtgcgat tattggtact gcatttggta ttttatctgg tcaaggagaa
    16621 actgctggta tcgctatagc agttccaatt gcagttgcta cccaacagtt ggatgttctt
    16681 gcaaaaactt tagatgttta ttttgtgaaa aaagctgata atgatgctaa aaacggagat
    16741 tattcaaaga tcggttttta tcattattca agtttggttt taatcacgtt atttaaaatt
    16801 gtaccaattt tcctagctat tatgcttgga ggggaatatg tggcagactt gtttgctaag
    16861 gttccaccaa tcgttatgca gggacttaac tctgcaggtg ctttactacc ttcaattggt
    16921 tttggtatgc ttttaaatat gatgctcaag aaaaatatgt gggtattctt gttgattgga
    16981 ttcatttgtt ctgtgtatgg aggaatgtca accattggga tctcactagt tggtattgcg
    17041 gtagcatact tctacgatat gattggaagt aaaccacaag aaacaacttc aagtagtgat
    17101 gttgaggagg atcttgatct atgatgaata ataaagtaac taaagttgaa cttaaaaaag
    17161 ttttcaaacg aagttttatg tatggttctt catggaacta tgagagaatg cagaacctag
    17221 gttttctata tacaattctt ccagtattga aaaaactata cccagacaaa gattcagctt
    17281 ctcctgcaat gaaacgtcac cttgagtttt tcaatactca tcaaacagcg gcaccattta
    17341 ttcttggagt tacttccgct atggaagaac aagaaggaaa tgaaggtgca gcttcaatta
    17401 ctggtattaa agttggcttg atggggccac tggctggtct aggagatagt ttgttctggc
    17461 tgacactagt tcctatctgt tttagtattg gtgcgtctta ttctaaagac ggcggtgctt
    17521 taggtatctt tatcgcctta atattgttta atattattaa tattcctgtt aaatatttcg
    17581 gtttgaaata tgggtatact aagggttcta gtcttatcca agaaaataat acaaaaggaa
    17641 cattgaatcg cgttacgagt atggcgacag cattagggct agtactagtg ggtggtttga
    17701 ttccatcaat ggttggtatt aattttggat tagaatttaa gcagggggaa cttgttattt
    17761 ctgttcaaga aatgattaca aaattaattc caggatttat ccctatggct ttgactttat
    17821 taatgtgtaa attaattaga aaaggaaaga atccggttgt actaatcttt agtgttatgg
    17881 ctattggagt tatcctagtt gttttaggaa ttttgaagta gtagaaagtg tggaggtggt
    17941 atttgggata tcacctccat tttggaagag aggtaaagag tgaaattatg gtataagaaa
    18001 gctgcctcaa attggaatga agccttgccg attgggaacg gtcatttagg tggtatgatt
    18061 tatggttcag ctacaaaaga atgtattcaa ctaaacgatg agactatttg gtatagagga
    18121 aagtcagata gaaataatcc agactcacta ttgcatctta aaaaaattcg ggaatatctt
    18181 ttagatggag aaattcagaa agccgaagaa ttgataaagt taacaatgtt tgctacccca
    18241 agagatcaaa gccactatga attacttggg gaactttaca ttgagcatat agatattcag
    18301 tcttgtgctc tttcattgta tgaaagagag ctagatttag atacagctat ttctaatgtt
    18361 gtgtttgagc ctaatagttg taatttacaa ataaaaagag aatattttac gagttttaat
    18421 aagaatattt tatgttgccg tatagtgtca tcagttcaaa acacattaaa tttaaacatt
    18481 aatttgggta gaaataaacg gtttaatgat gaagtatcta aactggattc aagtacaatt
    18541 ttaatgtcgg cctctgctgg aggtagaaaa ggtgttcagt ttaaagtagt atgtcattct
    18601 aaggttacgg atggtgaagt aagtgtattg ggagagacaa tagttattcg gaatgctaca
    18661 gaggtatttc tttatctcaa atcaatgacg gattattggg gaaatataga tatttcttct
    18721 cttcagggag aatttagtag tattgattac tttacagaaa aagatgaaca tgtaaaaaaa
    18781 tatcaggagc aatttaatag agttgatttt aaactagact atagtaaaga ttgtcttagc
    18841 attccaacga atctacttct tgaaaacact aaaaagtata gtaactactt gactaacttg
    18901 ttatttcatt atggaagata tctgttaata tcgtctagtc aaccgaatgg tttacctgcc
    18961 aatcttcaag gaatatggtg tgatgaatta aatccaattt ggggttctaa atatacgatt
    19021 aatattaata ctcaaatgaa ttattggatg gtaggtccat gtgatttacc agaagtagaa
    19081 tatccattat ttgatatgct cgaaagaatg agagaaccgg gaagactaac cgctaagaaa
    19141 atgtatggag ctagaggttt tacagcacat cataatacgg atggttttgg cgatacggct
    19201 ccccaatctc atgccatggg ggctgcaatt tgggtattaa ctattccatg gttatgtact
    19261 catatttggg aacactattt atatttccaa gatgagcgta ttcttacgga acattttgaa
    19321 atgataaaag aagcatttct tttctttgaa gattatttat ttgaggtgga tggctacttg
    19381 atgacaggtc caagtgtctc accggaaaat aaatatcgct taaaaaatgg tattgaagga
    19441 aatgcttgtc tatcatctac aattgataat caaattctaa gatatttttg tgattcatgc
    19501 attggcattg caaaacaatt aggagacaat tcggatttta ttagtcgtgt gaaggagtta
    19561 aaaaagaaac tacctaaaac aaaaataggt agtaatgggc aaatccaaga atggttagaa
    19621 gattatgaag aagtagagcc tgggcataga cacatttcac ctctatttgg gctttatcct
    19681 tataatgaga ttgatattca taaaactccg gaattagcag aagcagctaa aatcactatc
    19741 aataggagat tatcaaacgc taatttttta tcttcacagg agagggagca agcgattaat
    19801 aattggttag taagtggttt gcatgctagt acacaaacag gttggagtgc tgcatggctg
    19861 attcattttt ttgcgagact atatcaaggt gaacctgctt ataaccagat taatggtttg
    19921 ttaaataatg cgactcttgg caatttattt cttgaccatc caccatttca aattgatggt
    19981 aatttaggtt tggtgagtgg aatttgtgaa ttattagtac agagccatca taattggtta
    20041 tcactaattc cagctttacc ttctgcttgg tcagaaggag aagtgaaagg tttcagagta
    20101 agaggaggat ataaggtatc gtttgcttgg aaaaatgggg atataacatt cctaaaattg
    20161 gaaggaggaa acaaagatca aaaagtaaga gtaagaatat atggcaaaaa tactgatgta
    20221 caaaatattg aattggtatt taattcagaa aaaattattg agttaaattt ttaggtataa
    20281 gtcatgaata aagaaaaaat aaaaagaaaa ttaatcacaa tattgtttgt atgtattggg
    20341 atgttatgtt ttggattgtt agcaggagtt aaggctgata atcgtgttca aatgagaacg
    20401 acgattaata atgaatcgcc attgttgctt tctccgttgt atggcaatga taatggtaac
    20461 ggattatggt gggggaacac attgaaggga gcatgggaag ctattcctga agatgtaaag
    20521 ccatatgcag cgattgaact tcatcctgca aaagtctgta aaccaacaag ttgtattcca
    20581 cgagatacga aagaattgag agaatggtat gtcaagatgt tggaggaagc tcaaagtcta
    20641 aacattccag ttttcttggt tattatgtcg gctggagagc gtaatacagt tcctccagag
    20701 tggttagatg aacaattcca aaagtatagt gtgttaaaag gtgttttaaa tattgagaat
    20761 tattggattt acaataacca gttagctccg catagtgcta aatatttgga agtttgtgcc
    20821 aaatatggag cgcattttat ctggcatgat catgaaaaat ggttctggga aactattatg
    20881 aatgatccga cattctttga agcgagtcaa aaatatcata aaaatttggt gttggcaact
    20941 aaaaatacgc caataagaga tgatgcgggt acagattcta tcgttagtgg attttggttg
    21001 agtggcttat gtgataactg gggctcatca acagatacat ggaaatggtg ggaaaaacat
    21061 tatacaaaca catttgaaac tggaagagct agggatatga gatcctatgc atcggaacca
    21121 gaatcaatga ttgctatgga aatgatgaat gtatatactg ggggaggcac agtttataat
    21181 ttcgaatgtg ccgcgtatac atttatgaca aatgatgtac caactccagc atttactaaa
    21241 ggtattattc ctttctttag acatgctata caaaatccag ctccaagtaa ggaagaagtt
    21301 gtaaatagaa caaaagctgt attttggaat ggagaaggta ggattagttc attaaacgga
    21361 ttttatcaag gactttattc gaatgatgaa acaatgcctt tatataataa tgggagatat
    21421 catattcttc ctgtaataca tgagaaaatt gataaggaaa agatttcatc tatattccct
    21481 aatgcaaaaa ttttgactaa aaatagtgag gaattgtcta gtaaagtcaa ctatttaaac
    21541 tcgctttatc caaaacttta tgaaggagat gggtatgctc agcgtgtagg taattcctgg
    21601 tatatttata atagtaatgc taatatcaat aaaaatcagc aagtaatgtt gcctatgtat
    21661 actaataata caaagtcgtt atcgttagat ttgacgccac atacttacgc tgttgttaaa
    21721 gaaaatccaa ataatttaca tattttattg aataattaca ggacagataa gacagctatg
    21781 tgggcattat caggaaattt tgatgcatca aaaagttgga agaaagaaga attagagtta
    21841 gcgaactgga taagcaaaaa ttattccatc aatcctgtag ataatgactt taggacaaca
    21901 acacttacat taaaagggca tactggtcat aaacctcaga taaatataag tggcgataaa
    21961 aatcattata cttatacaga aaattgggat gagaataccc atgtttatac cattacggtt
    22021 aatcataatg gaatggtaga gatgtctata aatactgagg ggacaggtcc agtctctttc
    22081 ccaacaccag ataaatttaa tgatggtaat ttgaatatag catatgcaaa accaacaaca
    22141 caaagttctg tagattacaa tggagaccct aatagagctg tggatggtaa cagaaatggt
    22201 aattttaact ctggttcggt aacacacact agggcagata atccctcttg gtgggaagtc
    22261 gatttgaaaa aaatggataa agttgggctt gttaaaattt ataatcgcac agatgctgag
    22321 actcaacgtc tatctaattt tgatgtgatt ctatatgaca ataatagaaa cgaagttgct
    22381 aagaaacatg ttaataattt gtcgggtgaa tctgttagtc tagatttcaa agaaaaagga
    22441 gcaaggtata ttaaagttaa attactaacg agtggagtgc ctttgagttt agcagaagta
    22501 gaggttttta gagaatcaga tggtaagcaa tctgaagagg atatagataa aataacagaa
    22561 gataaagtag tctctacaaa taaggtagct actcaaagtt caaccaatta tgagggtgta
    22621 gctgctttag cagttgatgg taataaagat ggagattacg gacatcattc ggtgactcat
    22681 actaaggcag attctaacgc ttggtggcag gtcgatctgg gagaagagtt tacggtttct
    22741 aaagttgata tttataatag aacagatgcc gaacctcagc gtttatctaa ttttgatgtt
    22801 atttttctat cttcatcagg agaagaagtt tttagaagac attttgataa agtagttgat
    22861 ggtttgttat ctttaaaagt accttctgta ggggctaagc tagtcaaaat agaattaaaa
    22921 tcagcagcta ttccgttaag tttagcggaa gttgaagtct atggttcaaa gagaactccg
    22981 aagaaacttt ctaatattgc attaacaaaa gaaactcgac agagttcaac ggattacaat
    23041 ggtttttctc gtctagcagt tgatggaaat aaaaacggag attatggtca tcattcagtg
    23101 actcatacca aagaagattc tccttcatgg tgggagatag atttagcaca aaccgaagaa
    23161 ttagaaaagt taattattta taatagaaca gatgctgaaa ttcagagatt atcaaatttt
    23221 gatattatta tatatgattc aaatgattat gaagttttta cacaacatat tgacagttta
    23281 gaaagcaata atctatccat agacttaaaa ggactgaagg gaaaaaaggt tagaatttct
    23341 ttgagaagcg caggaattcc tttaagttta gcagaggtag aggtttatac ttataagtaa
    23401 ttttaaaaat tatcacccag gctaccgtaa atataatgga gatggtagta tgaaagaaac
    23461 agaaaaataa gaggaaaata gtatgattca acatccacgt attgggattc gtccgactat
    23521 tgatggtcgt cgtcaaggtg tacgcgaatc acttgaagtg caaacaatga acatggctaa
    23581 aagtgtggca gatttgattt caagcacatt gaaatatcca gatggggaac ctgtggaatg
    23641 cgtgatttct ccatctacta ttggccgtgt accagaggct gcagcttccc atgagttgtt
    23701 taaaaaatca aatgtttgcg caacaattac agttacacca tgctggtgtt atggtagtga
    23761 aactatggat atgtctccag atattcctca tgctatttgg ggatttaatg ggacagaacg
    23821 cccaggagct gtctatcttg cagctgtact agcttcacat gctcaaaaag ggattccagc
    23881 ctttgggatt tatggaagag atgttcagga agctagtgac acagatattc cagaagatgt
    23941 caaagaaaaa cttttacgct atgcgcgtgc agctcttgca actggcttga tgagagacac
    24001 tgcttaccta tcaatgggta gtgtttcgat ggggattggt ggttctattg taaatccgga
    24061 tttcttccaa gaatacctag gaatgcgaaa tgaatcggta gatatgacgg agttcacgcg
    24121 ccgtatggac cgtagtattt acgaccctga agagttcgaa cgtgcgctca aatgggtgaa
    24181 agaaaacgta aaagaaggat tcgaccataa ccgtgaagac cttgttttaa gccgtgaaga
    24241 aaaagataga caatgggaat ttgttattaa gatgttcatg attggacgtg acttaatggt
    24301 tggtaaccca agacttgctg aacttggttt tgaggaagaa gcagttggtc accatgcttt
    24361 agtagctggt ttccaaggtc aacgtcagtg gacagaccat tttccaaatg gagattttat
    24421 ggaaactttc ctcaatactc agtttgactg gaatggtatt cgaaaaccat ttgtatttgc
    24481 gacagagaat gattcactaa atggtgtgtc tatgctcttt aattatctat taacaaatac
    24541 tccacaaatc tttgctgatg tgcgtactta ttggagccca gaggctgtta aacgtgtaac
    24601 gggacatact ttagagggtc gtgctgcagc tggcttctta catctaatca actctggttc
    24661 ttgtacattg gatggtacag gtcaagctac tcgagatggc aaacctgtta tgaaaccatt
    24721 ctgggagttg gaagaaagtg aagtgcaggc tatgcttgaa aatacagact tcccaccagc
    24781 aaaccgcgaa tacttccgtg gaggaggatt ctcaactcgt ttcttgacga agggggatat
    24841 gccagtaaca atggtacgtc tcaatcttct aaaaggggtt ggtccagtgc tacaaattgc
    24901 agaaggttat acacttgaac ttcctgaaga tgttcaccat actttagata atcgtacaga
    24961 tccaggatgg ccaactactt ggtttgctcc acgtttgaca ggaaaaggtg ctttcaagtc
    25021 tgtctatgac gtcatgaata attggggagc taatcacgga gccataacat atggacacat
    25081 tggagcagac ttgattacct tggcttctat gttgagaatt cctgtcaata tgcataatgt
    25141 acctgaggaa gatatcttta gacctaaaaa ttggtcctta tttggaacag aagatctaga
    25201 atcagcagac tattgtgcat gtcagttgtt gggaccacta cataaataaa acttgtttat
    25261 ataggaggtg aacttacgtc cctcctatcc ttttaaaaag atttgttaaa caattcacaa
    25321 ataattaaaa acgaatacaa aaagtaatat aatgatgtta aatagatagc gcggaggcgc
    25381 aggaggaaaa ttatatggct acattttatg ttccggcagt caaccttatt ggaaaaggtg
    25441 ttgtaaatga agtgggtcct tatatcaagg aacttggcta taaaaaggca cttttggtta
    25501 cagataagta catcgaaggc agtgatattt tacctaagac tttaaaacca ctggatacag
    25561 aaggaatcga atatgtcatc tttagcgatg tagagccaaa ccctacttgt aaaaatgtca
    25621 cagatggggt agctgctttg caagaacatg gctgtgactt tatcatcagt cttggcgggg
    25681 gttctccaca ggatgcagct agttgtattt ctatcatggc tacaaatggt ggaaaaccac
    25741 aggattatga agggcttcat aagtctgcta aaaaaggctt gccagttgtg gctatcaata
    25801 caacggcagg aacttctgca gaaatcacta ttaactatgt gattactgat gaagaacgca
    25861 aggttaagat ggtaatggtt gacaagaata gccttgctct tatctctgtt aatgacccgg
    25921 aactcatgct ttccaaacct aaaggcctga ctgctgctac tggtatggat gctctgactc
    25981 acgctgttga agctttggta acacctggtg cttatgatgt aaccaagaaa ctgtctattg
    26041 gtgctattga gcttatcaag gaatatcttc ctcgtgctgt agaaaatgga catgatattg
    26101 aagcgcgtga aggtatggtc aatgccatct tccttggtgg tatgagcttt aataatgctg
    26161 gtcttggtta tgttcactca atggctcacc aactcggtgc agtatataat ttgccacatg
    26221 gcgtgtgctg tgccatgttg ctaccagtta tagaacgtga aaatgctaaa cgtgtaccag
    26281 aagctttccg caatgttgcc aaagccttgg gacttcatgt agaaggtaaa tcagatcaag
    26341 aatgtgccga ttatgcgatt gctgagattg agaagctttc tgagacagta ggtattccta
    26401 agaaactgac tgaacttggt attgaagaaa aagatttcga ctttgaatac ctttctaaga
    26461 atgccttgat tgatgcctgc gcaccaggaa atccatttat gccaacctta gaagaaacga
    26521 ttgcctttta taaagagtta ttttagcaag agattggacg acaataggac aattcacctc
    26581 taattattga catttcagga aaaatcgcag taaaaacggc acagccttct ttaaatgtgc
    26641 tataatacta gaaaaatact tgtggaggtt ccattatggc aatatttttc atgatttttc
    26701 tgattgtttg tgtgctccta ttggtgatag tcacactgag tacagtttat gtggttcgtc
    26761 agcagtcggt ggcgattatt gaacgctttg ggaaatacca aaaggttgct aatagcggta
    26821 ttcatattcg cttgcctttt gggattgact cgattgcagc acggattcag ttgcgcttgt
    26881 tgcaaagtga tattgtggtt gagactaaga ccaaggacaa tgtgttcgtt atgatgaatg
    26941 tagcgactca gtaccgtgtc aacgagcaga gcgtgacaga tgcttactat aaactcatac
    27001 gtccagaatc tcagattaaa tcttatatcg aagatgctct tcgctcttct gttccaaaat
    27061 taaccttgga tgaattgttt gagaaaaaag atgagattgc ccttgaggtt caacaccaag
    27121 tagcagaaga aatgaccact tacggctaca ttatcgtgaa aaccttgatt accaaggtcg
    27181 aaccagatgc agaagttaag caatccatga atgaaatcaa tgcggcgcaa cgtaagcggg
    27241 tcgcagcaca agaattggcg gaagctgaca agattaaaat tgtcactgca gctgaagcag
    27301 aagcagaaaa agaccgcctt catggtgtgg ggattgccca acaacgtaag gcgattgtgg
    27361 atggattggc agagtctatc accgaactca aggaagccaa tgttggcatg acagaagaac
    27421 aaatcatgtc tatcctcttg accaaccagt atttggatac cttgaatacc tttgcctcta
    27481 aaggaaatca aaccatcttt ttaccaaata ctccaaatgg tgtggatgat atccgaacac
    27541 aaatcttgtc agcccttcgc gctgagaaga aataatagac taatactctt cgaaaatctc
    27601 ttcaaaccac gtcagcgtcg ccttgccgta tagatgttac tgacttcgtc agttctatct
    27661 gcaacctcaa aacagtgttt tgagctgact tcgtcagtct tatctactac ctcaaaacgg
    27721 tgttttgagc aacctgtggc tagtttccta gtttgctctt tgattttcat tgagtataaa
    27781 gagcttggca acaggctctt tttgtattgc gtttattaag aaaaacaaaa aacatcgata
    27841 tacatttaac taaaaattat tgtatgtcat ctcccttaat taggaatgat aagggaataa
    27901 ctagaaagat ttgtgaatac aaactatttc tgatatacaa aatatacagt aataatgaat
    27961 gatgggagat gggatgaaag aatttcaatt tgagagaaag cagcgttttt ctttgaggaa
    28021 atatgcaata ggagcttgtt cggtcttgct aggaacgagt ttattttttg ctggtatggg
    28081 tgctcagcct gtacaggata cagaaacgag ttcagcacta atttcaagtc attatttgga
    28141 tgagcaggat ttatctgaaa agctgaaatc tgagttgcaa tggtttgaat tagaaaacaa
    28201 gcttttgaac ttatgggagc attaggttac tatgaaggat ttgttcctta tgtttcaaat
    28261 caatacaaaa accaagctga agaagaatac aaaccgctat ctgataaata tattttcgaa
    28321 aaaatcttag gaaaaacata tgcagccttc aaaaaagatc aaattaatga gcgtgtcgag
    28381 aaattaggta agttaaaacc tattacaata aattacaacg gaaaatcaga agtaattgat
    28441 agtaaagaaa aattacaaga gcttatgaat aaagccgtta aagacgaagt ggctcaaata
    28501 tagtaaaatg aaataagaac aggacaaatc gatcaggaca gtcaaatcga tttctaaaaa
    28561 tgttttagaa gtagaggtgt actattctag tttcaatata ctataaaatc aggcaatacc
    28621 acggctaaaa agtttgagtt tatcgaaaca ccagtgcaaa aactgaaaaa agcgatttat
    28681 aaagctcatc tcaaagattc agatgacttt agaccagaaa catccacacc aaatcttttt
    28741 gaaagctgtt tgaagctttg tccttgcttt cttagttcat agatctgaac tttatcttca
    28801 taactcaatt tcataataaa acaccccaaa agttagattt attctgtcta acttttgggg
    28861 tgcagttcat taatcggtcg attttttttg gtagaaacag ttgcctgatt aagttgcaag
    28921 tcgatagacg gcttcggcat aaatatccat agcacggtac aaatcttcta gaacggcaca
    28981 ttcatttgcc tgatgttctg tttgcttcgc tcctgggaat aaggcgccga aggctacaca
    29041 atttggcatg gtgcgagcaa aagtggcacc accggatgaa atagcaggac tgttatcgcc
    29101 agtcttttct tggtagattt gcatcagtgt gctaacgagt ttactgtctt ttgcgacgta
    29161 tagaggcgct agatagtcaa actcttcgta gcggagttgg tagttttgtg cacatcttgt
    29221 aagcaactct actagttctt ccttgtcagc taagacagga gtccgaatgt caatacggat
    29281 ttcagaacgt tcatgattga tcatgagacc tgcgacatta aaggataggt gaccagaagg
    29341 ttcatctgct atatcaccaa agatttgtct tcctgtgccg tcttgacctg cttgtgttgc
    29401 aagaaaactg agagcagggt gttcttggag aggagcaaga atggtagcta gtcggatgac
    29461 agcattgata ccttgactag catccttagc atgctttggc actccgagaa ccgttacggt
    29521 ttgttcagtg gattggtaat cataaccagc ttctttgaga ccgttacaaa cctgttcata
    29581 gaggggacct tggtagttgg ccttgtctgg tacaacgtta aaggcgcctc ctacttcaag
    29641 ctctagttga tccgatccag ggccatgaag tttgacctgt agaagccctt tttcagcata
    29701 ggtcagagga aaagatgagt caggtgcaaa gcccatactg gcctgttctt cgatggtatt
    29761 gtagcgtgcc atgcagcgcc agagggtttc ctcatcggta ccaaagataa agcgtacgcg
    29821 ctttttgaac tgaatacctt ggtccagcaa gctttttact gcatagagag ctgcgagcga
    29881 agggccttta tcatcttgga caccacgtcc gaatacccag ccgtctttga tagttgcttc
    29941 aaatggcggt gtctgccaat ctgcttcatc acctgatgga acaacatcca aatgacagag
    30001 aatggccaga agctctgctc cctgaccgat ttctgcatat ccgtaataac ctttagggtc
    30061 aagataggta gtgaaaccta tgtctcgaca aatctctaaa gttttttcta ggacatcttg
    30121 gattgcttgt ccaaaaggtg ttccattttc tccttcattg agtactgaag gataggaaat
    30181 caaggttttt aatgatataa gaaattcatc tttaacttga tttgttatat ctattttcat
    30241 ggaatcacct cactcactat tttataggaa tggaaggaag gttccaagga gaagaagggc
    30301 gatggtcact acaataatag cgactacgag tttgcccatg aatttccacc aagtaccaat
    30361 gttgatacgt ccaagtgcaa gagctcccat cacaatacca gatgttggtg caatcaagtt
    30421 caagacacct gaagcagatt ggtaagcagt gataatcaag ctaggacgga catttacaaa
    30481 ttctccaagt ggagccatga tacccatagt tgcgctggca agaccagatg aagatgggat
    30541 caagaatgac ataggtagat agaagatata agttacaacg ataaagactt gtgaagatag
    30601 accgctcaag ccttctttac cccagttgag gattgtatcg gtaatcatac cgtcgttcat
    30661 gataacttga ataccacgag caatcgctac gatcaaggca acactgagca agtcagcagc
    30721 accattcatg aaggaagaga taatcttatc ttctttaaga ccataaataa caccaatcag
    30781 gatacccata aaggcaaaga gcattgcgcc ttctgggaag taccaagtac ctagtgcaga
    30841 agtagatgaa ccgacaatat taccaataac tggaagacca gtcaaccaag tattaaagtc
    30901 atcaaaaatg gtaacgccaa ggtctgtcca tggaatgaag ctcaatacca tcaagatgaa
    30961 tgtcaacaca aataagaaga gaactgattt ttgtttgctg ctaagtgtag attctacaga
    31021 tgaagattct tctacgttaa agtgtttcaa atcttctttg cgagtactat aaaccagtga
    31081 cttagtcgga tctttttgaa tcttatccgc ataacggtaa acaaaccaag tactaagagc
    31141 agtcaaggta acccagaaga tcagacgaag tacgataccg tcccctgtac caactcccgc
    31201 agtcgctgaa gcaatacctg tcgcaaatgg attcagagta gatgccaaac agccgatttg
    31261 agaaccgagc aaaataattg caacaccagt caggctatca aaaccaacgg ccatcataac
    31321 tggcacaagg agtggataga aagccattgt ttcttcaccc ataccataag ttgtaccacc
    31381 gagggcaaac aaaggcatca gtaccaaaat taacattttt tcgcggccct tatacttctt
    31441 cacgatagag gcaatcccta cgtcaagagc accagttttg ttgacaatgc caaggaaacc
    31501 accaaccata aggatgaaga aggctacatc aatcgctgcg ctcgtttctt taatgagcga
    31561 accttcctct ggatgagtac ctagcatagc ccgaatcggt gccatgagga catcccaaat
    31621 cccttgtgga ttttgaggct gagtctcgta aataccttct ataaaggccc ccgcagggat
    31681 aaaccaagtt agcactgcca taatagcaat gattatcaat aatacggtgt aagatgaagg
    31741 catcttaaac ccttttttag ctttttcact catttgtttt tcctcctgat gtctaacaaa
    31801 gtgtaaaaaa ccaactactt tcttaaataa acatttaaga aaacgctttc tatttatatt
    31861 tgttttacca tattaaagtc taaaaaacta atatcttttg aaatattgta catgttttca
    31921 agaataattt ctaatttgat ataaagatac tagaaataga atacatctta ttagtaaaac
    31981 aacttatcct ttttcaataa ttgttccact ttcagattca atcaaggcgc ctagattttc
    32041 aagggaagta ataactgctt ttccttctgg acgaccattg acaaaagcga tagctgcttc
    32101 tacttttgga agcatgctac ctggtgcaaa ctgatcttgt ttgatatatt cttccagctg
    32161 ggcaacattc acatgttcca atttttcctg gtttggcttg ttgtagttaa caaatacata
    32221 atctacacct gtcaaaatga tgaagaggtc tgcatcaacc aattctgcca aacgttggga
    32281 agcgaagtct ttatcaataa ccgcttcgac accagtcaaa tgtccattgt tttctttgac
    32341 gacgggaata ccgccaccac ctgcagctac gacgacttga ccattattta aaagagtacg
    32401 gatggtttca atttctttga tgtcaacagg ttttggtgag gcaacgacct tacgccagcc
    32461 acggccagca tcttccttga aagtcgctcc gcttttttcg gcttctgctt ttgcttcttc
    32521 ttctgaatag aaaggaccga ttggtttact caagttaaca aaagctggat catttttatc
    32581 tacgacaact tgcgttacaa cagaggcaac atttttttcg atgccttcat ccaagagagc
    32641 attttgcaaa gcatttttca accagaaacc gatgctacct tctgtcatag cgacaagtga
    32701 gtcgagtggg aaggcagggt tcttttcaga gtctgatgcc aaatgttgga gcaagagatt
    32761 cccaacttga ggtccattac cgtgagtgat aatcaaatca tctccatttt taatcaattt
    32821 tacaagatgc ttagctgttt caactaaagc ttcttgttga gcctttgctg atgggtcaga
    32881 agaaagaatc gcatttcctc ccaaagctac tacaatttta cgatttgcca taaattctcc
    32941 tttatcacac tcaatagaat gcgtttagat ttcaatttaa tgatttttca catattttat
    33001 aagaaataat agattaccat tacataaaag aggaccggac taaagctatt agtcgcagcc
    33061 ctcatagctg ttggtagacg gtttattatc taaaattata ctttaggaat ataaaggtta
    33121 ccaagtgtcg cagccataac agctttgata gtgtgcatac ggttttctgc ttgatcgaag
    33181 tggcgagcgt acttgctgcg gaagacttcg tctgttactt ccatttcttc tacaccaaat
    33241 ttttcagcaa cgtctttacc ataaacagtg tgagtatcgt ggaatgctgg caagcagtgt
    33301 aggaagatca agttttcatt gcctgctttt ttaactaagt ccatattgac ttggtaaggt
    33361 ttaagaagag ctacacgttc tgcgaatttg tcttcttcac ccattgatac ccaaacgtct
    33421 gtgtaaagaa cgtctgcatc tttaactgct tcatcagcat cttcagtgat gagaacatgt
    33481 gcgccacttt ctttagcaaa tccttctgcc aattcaacga tttctttttc ggggaagagt
    33541 tcttttggtg agaagatgtg aacattgaca ccaaggatag cacctgttac gagcaagctg
    33601 ttggcaacgt tgttacgtcc atcaccacag tataccaatg tcaagccttc caagcgaccg
    33661 aagttttctt gaacagtcaa gtagtcagcg agcatttgag ttgggtgcca ttcgtcagtt
    33721 agaccgttcc atactggaac gcctgagaat tctgccaatt cttcaaccat acgttggctg
    33781 aatccgcgga attcaatccc gtcaaacata cgtcccaata ctttagcagt atcttcagta
    33841 gattcttttt tacccaactg aatatcattt gctccgaggt attctgggtg agcaccaagg
    33901 tcgatagccg cagttgtaaa ggctgcacga gtacgagtag atgttttttc aaataggaga
    33961 gcgatattct tgccagcaag gtagtggtgt tgaatattgc gttttttcaa atctttcaag
    34021 tgagctgaaa gaccaataag gtattctaac tctgcacggg taaagtcttt ttctgctaag
    34081 aagctgcgtc cttggaatac tgaatttgtc attttattat ttcctctttc tattttttac
    34141 attttctatt gacgaatgcc gaacagcgat tacacttctt cacgttcaaa tggcatagac
    34201 atacaacgag gtccaccacg gccccgaacc aattcacttc cgcgaatctt aatcaagcga
    34261 agcccgtatt cttccaaaat cttattggtc acggtattgc ggtcataaac aactaccaca
    34321 ccaggtgcga tggtcaaagt gttagaaccg tcgttccatt gttcacgcgc agctgctacg
    34381 atattgccac caccgcaacg aatcaaatga actttttcta caccaaggtt ttgagcaaga
    34441 agttcagcta agtcaccttt ctcttcaacg attttaagtt tttcgttttc gtaagtaact
    34501 gagtaaacgt gaaggtcgcc ttcgatttct gggtgaatag tgaacttgtc atagtctacc
    34561 atagtgaaga cagtatccaa gtgcatgaat ttacggttgt tagcaaattc aaaggccaaa
    34621 actttcttga agccaacatt tttcttgaag atgttgacca aaagtttttc gatagaagct
    34681 gcgtctgtac gttgagaaat acctactgca aggacgtctt tagaaagaac tagctcgtct
    34741 ccaccttcga tacgcgtatc ttcttcacgg ttgtagacca aatccacttt tccgccatag
    34801 attgggtggt atttgaagat atacttaccg tagagtgttt cacggttacg agtgtctgca
    34861 aacatgtggt taagcgatac ggcgtttcca attgttgcaa atgggtcgcg agtgaaatag
    34921 aggtttggca tcgggtcaat tgcaaatgga taatctgatt caactaagtc agttagatct
    34981 ttagcttcgt caggaatttc tggcaattca actttttgaa tcccagccat tgttttttca
    35041 accaattctt ggttgtcctt gatgccgtga agcaattcac gaatagcaac cttggtttga
    35101 cgatcacgga tgttggcttc gtctaagtat tcctcgataa attgatcgcg gatttctgga
    35161 gaggtcaatg attcagcagc gagttgttct aggtagagaa cctcaattcc ttcatcgcga
    35221 agagcttggg caaatgcatc atgttctttt tgagcatctt ccaagaaagg aatatcatca
    35281 aaaagaagcc tttcaagata gtccggcaac aagttttcta actccttgcc tggacggtgc
    35341 aacataactt ttttcagttt cccaatttct gagaagacct gaattggatg tgaagacatg
    35401 tattttcctc cttaaaaatt ttgacttggc accattttgg gtaccgctta catgtatgtt
    35461 ataacgcaat tcctaggtaa tgtcaatggc tataatttct cggaaaataa tataaattat
    35521 gatatttagc acaattttat gttattatac acaacatagg atggaataca tatatacaaa
    35581 tgcataaact tctattaaag aggatataaa atttttttaa aaaatttttc aaaaaataca
    35641 caaataacca aaaagtgtcc aattatcatc tggttatcac ttggatctgt ataaagagaa
    35701 atgtttgtgt gaaaggataa aaagatgcaa cattcttttg aagatagatt ttggagaagc
    35761 atttcttgct caattgtaca aattatagaa tcttttctga gtatttagga agagataatt
    35821 atcttattga ccctcttttt attttttgtt atagtcgacg agatgatagt ttagaataat
    35881 cacttattca caatctgtgg aaaagtctgg agagtgaatg gtcttcacac aatgacctga
    35941 aagaagcctg agaataatta tggagagtag cattctgaga ggtgttagca gaaccatatg
    36001 acagagctgt ttgaagaggg aacattgagg agcaaaatcc tgagcctacc agttggagtt
    36061 ggaaagagct ggcggttaga tcatttttta ttatccacaa cctgtggata accttgtgaa
    36121 caagagaagt tgctaaagaa ggagatatat aacgatgaag aaaatcaaac cgcatggacc
    36181 gttaccaagt cagactcagc tagcttatct gggagatgaa ctagcagctt ttatccactt
    36241 cggtcctaat accttttatg accaagaatg ggggactgga caggaggatc ctgagcgctt
    36301 taacccgagt cagttggatg cgcgtgagtg ggttcgtgtg ctcaaggaaa cgggcttcaa
    36361 aaagttgatt ttggtggtca agcaccacga tggctttgtc ctttatccga cagctcacac
    36421 agattattcg gttaaggtca gtccttggag gagaggaaag ggcgacttgc tccttgaagt
    36481 atcccaagct gccacagagt ttgatatgga tatgggggtc tacctgtcac cgtgggatgc
    36541 ccatagtccc ctctatcatg tggaccgaga agcggactac aatgcctatt atctggctca
    36601 gttgaaggaa atcttatcaa atcctaacta tgggaatgct ggtaagttcg ctgaggtttg
    36661 gatggatggt gccagaggag agggcgcgca aaaggttaat tatgaatttg aaaaatggtt
    36721 tgaaaccatt cgtgacctgc agggcgattg cttgattttt tcaacagaag gcaccagtat
    36781 ccgctggatt ggcaatgaac gagggtatgc aggtgatcca ctgtggcaaa aggtgaatcc
    36841 tgataaacta ggaacagaag cagagctgaa ctatcttcag tacggggatc cctcgggcac
    36901 gattttttca atcggagagg cagatgtttc catccgtcca ggctggttct accatgagga
    36961 tcaggatcct aagtctctcg aggagttggt cgaaatctac tttcactcag tagggcgagg
    37021 aactccactc ttgcttaata ttccgccgaa tcaagctggg ctctttgatg caaaggatat
    37081 tgaacgactt tatgaatttg cgacctatcg caatgagctc tataaagaag atttggctct
    37141 gggagctgag gtatctggtc cagctctttc cgcagacttt gcttgtcgcc atttgacaga
    37201 cggccttgag accagctctt gggcaaacga tgcagacttg cccatccagt tagaactcga
    37261 cttaggttct cctaaaactt ttgatgtaat tgagttgaga gaagatttga agttaggcca
    37321 acgtatttct gctttccatg tgcaagtaga ggtggatggt gtctggcagg aatttggcag
    37381 gggcttcaca gttggtcata agcgcctctt gcgaggtccg ctagtagagg cacagaaggt
    37441 gcgcgtgatg attaccgaag cacaatctat gcctctactg accaagattt ccctttataa
    37501 aactcctgga ttatcaaaaa aagaagttgt tcaggaacta gcatttgcag aaaaaagcct
    37561 agctgtggca aagggagaga ctcttcattt taggattgaa cgtagtgaaa gtagctcctc
    37621 tttagaggct aagatttcga ttcaaccggg gacaggtgtc catggtgtcg cctatcagga
    37681 tgagattcaa gtccttcaat tccaagcagg ggaaagcaaa aaagatttgc atctaccaac
    37741 cctgtatttc gcaggagata aaaccttgga tttctatctg aacctaacgg tggatggtca
    37801 gcttgtggat caacttcaag tccaagtttc ataaaagaag aacctttgcg cgatgcaaag
    37861 gttcttttgg ttattaatga cttggtaacc agctgagggt gaaagttagt tgttcagctt
    37921 ttaagaggtc ttggtgttga atagttgata cgagtgtttt gtccagtcgg cattctttga
    37981 caaagttaaa atggttgtgg ttttgtttag tatggatatc cagccattta tcttctttag
    38041 cgaggtagac tcgtagatgg tcaaagagag ggattccgag gtcatagctt ggttttcctg
    38101 gacaggttgg ataaaatccg agagctgacc agatgtacca agcagagaga ctaccattgt
    38161 cttcatctcc aggataggct tcccaacttg ggtgaaaagc tttctgacgg agcgtcttga
    38221 taagaagggc agtgtagtca gggtaatcgc tgtaacggaa gagataagga atgtggaaac
    38281 taggctggtt ggaaatggct atttgtccaa aaggagcagt agccatctcg ctcatttcgt
    38341 gaatttcgta accatagcct gttgtttcaa agaggggagc atcttgacag gctttcaaaa
    38401 gatagttgct aaaggtttct tttccaccca tcagttggat taagccaggg atgtcgtgga
    38461 gaacgcctaa agtagcttga atggcagagc attcagcgta gtctcgcccc caactataag
    38521 gagagaagtc agggtgaaag tttccttgat tgtctcgtgc tcgcatgtaa cctgtctcag
    38581 cgtcaaatag ctggcggtaa ttttgtgaag cagccttgta ggtttcagcg atttctatgt
    38641 tttttagttt tttggcacag ttggcgatac aaaagtcact ataggcatag tctagagtat
    38701 ggctaacact ttcgtggtgg tcggtagaga ggtaacctag ttcttggtat tgggctagtc
    38761 cgtggcggcc attgattccg agagggtcgg ctttgctggc tgtttcgagc atggcttgga
    38821 agagttctcc ttctaggtca ggggccatgt ccttgcaggc gctatctgcg ataataccgt
    38881 ctaaaagtgt acctggcatc ataccccgtt catctggagc cagccatttt ggaaggaaac
    38941 cagtatcgcg gtagctattg aggaaacctt ctaaaaagcg ttgatagtgc tccggtatga
    39001 taagggcaaa gagggggaag gtggtgcgga aggtatccca gaaaccattg ttgctaaaga
    39061 ggacaccagg cttgacagta ccagtagcca gatccatgtg gatggcttgc cctgattcat
    39121 taatctcata aaaagtctgt gggaagagga agagtctgta gaggcagtgg tcaaagaagg
    39181 ttcggtcagc ctctcctatc tctataatgt caaaacgatg gaggagattt tcccaatccg
    39241 cttgggcact tgatttacag ctatcaaaat cttcttgagg tagattaagc agtgcttgag
    39301 aaggagagat gaaagaagtg gctagttgca tctcggtttg actacttgct aagtcaattc
    39361 gccagtctcc cccttcttgg ctgatagcaa gaatatccgt gttcatttgc agggcagtga
    39421 acatcgttag cgaatttttg ttagtttcag ttttaccttc ttgtcgcagg gcaagagtcc
    39481 gcttatctac ttgctctact gtcagttcat ctgctgcgtg aagatagagg gagagggctt
    39541 tgccttgctt ttgcttcaaa cgaatagaag caccatagca agtcggtgtg agctgggttt
    39601 caatctgata acgcagagaa aagagcttca aatagtgagg ctggaagcaa gctttatcta
    39661 tatcataaga agactggcgg tgaaagaggc tgtctccccc cagttgactg gtgacaggtg
    39721 tcagaaggag ccaagagtag tccccaatcc aaggactggg ctggtgagtt aatcgaatcc
    39781 cctgaaagat aggcagatgc ggatcaaaaa accaagatcc accctggtca ctggtctggg
    39841 gcacaaagta attcatccca aaaggcacgc ctgtgtatgg cagggtattt ccccgagaga
    39901 aggcatgctt gctagcagta ccaaagcggg tatcgatggt ttcaagtagt ggtttcatag
    39961 tctttccttt agctgttttt ctacattata tcagaaaaag agggccttta gaaaaggagt
    40021 ttcaaaaata actattttgt agaaaaatga ctatcatttg tgtatgtatt ttctgtctca
    40081 aaagctatat actgaacatg aaacttgttt gaaagaggga attgcacgat gatttattcg
    40141 aaagaaattg ttagagaatg gctagatgaa gtagcagagc gggctaagga ccatccagag
    40201 tgggtggatg ttttcgagcg ttgctacacc gataccttgg acaatacggt tgaaatctta
    40261 gaagatggtt caacttttgt cttgactggg gatattcctg ccatgtggct tcgagattcg
    40321 acagcccaac tcagacccta ccttcatgta gctaaaagag atgccctcct gcgtcagacc
    40381 attgcaggtt tggtcaaacg tcagatgacc ttggtactca aggatcccta tgctaactcc
    40441 ttcaacattg aggagaactg gaaagggcac cacgagactg accacacaga ccttaacggc
    40501 tggatctggg agcgcaagta tgaggtggat tcgctttgct atcctttgca gttggcttat
    40561 ctcctctgga aagagactgg cgagactagt cagtttgatg agacttttgt cgcagcgact
    40621 aaggaaattc tccatctgtg gacggtggaa caagaccaca agaactctcc ttatcgtttt
    40681 gtccgagata cggaccgtaa ggaagacacc ttggtaaatg atggctttgg acctgacttt
    40741 gcagtgacag gtatgacttg gtcagccttt cgtccgagcg atgactgctg tcagtatagt
    40801 tacttgattc cgtcaaatat gtttgctgta gtagtcttgg gttatgtgca agaaatcttc
    40861 gcagcattaa acctagctga tagccagagt gttattgctg atgccaagcg tcttcaggat
    40921 gaaatccaag aaggaatcaa aaactacgct tacaccacca acagcaaggg cgaaaagatt
    40981 tacgcttttg aagtggatgg cctaggaaat gccagcatca tggatgatcc aaatgtacca
    41041 agtctactag ctgcgcccta tctgggctac tgttcggtcg atgatgaagt gtatcaagct
    41101 actcgtcgta ccattttgag ctctgaaaat ccatatttct accaaggaga atacgctagc
    41161 ggtctcggaa gttctcatac cttctatcgc tatatctggc caatcgccct ttctatccaa
    41221 ggattgacaa caagagataa ggcagagaaa aaattcttgc tggatcagct ggttgcctgc
    41281 gatggtggta caggtgtcat gcacgaaagc tttcatgtag atgatccgac cctctactct
    41341 cgtgaatggt tctcctgggc taacatgatg ttctgtgagt tggtcttgga ttacttggat
    41401 attcgctaag gggctcgctt tagctcaacc gattcttatc agaatcacaa gtttacattt
    41461 aaaacgttaa aatttaaatt tagaatgagg ttttacttca tggaaaatgt tgttgtacat
    41521 attatctcac atagtcactg ggaccgtgag tggtacttgc cttttgaaag ccatcgtatg
    41581 cagttggtgg aattgtttga caatctcttt gatctctttg aaaatgaccc tgagttcaag
    41641 agtttccact tggatggaca aactattgtc cttgacgact acttacaaat tcgccctgaa
    41701 aatcgtgaca aggtccaacg ctacattgac gagggcaaac ttaaaattgg tcccttttac
    41761 atcttgcagg atgactactt gatctccagt gaagccaatg tccgcaatac cttgattggt
    41821 caacaagaag ctgccaaatg gggtaaatca acccagattg gctactttcc agataccttt
    41881 ggaaatatgg gacaagcgcc tcaaattctt caaaaatcag gcattcacgt ggcggccttt
    41941 ggtcgtggtg tgaagccgat tggatttgac aaccaagtcc ttgaagatga gcagtttaca
    42001 tcccagtttt cagaaatgta ctggcagggt gtggatggta gtcgtgtttt aggtattctc
    42061 tttgccaact ggtacagtaa cgggaatgaa attccagttg acaaagatga ggccttgacc
    42121 ttctggaaac aaaaattgtc agatgtgcgt gcctacgctt cgaccaacca atggttgatg
    42181 atgaacggct gtgaccacca gcctgtacag aaaaatctga gcgaagccat tcgtgtggca
    42241 aatgaactct tcccggatgt aatctttgtt catagttctt ttgatgaata tgttcaagct
    42301 gtagaaggtg cgcttcctga acacttatca actgttacag gcgagttgac cagtcaggaa
    42361 acagatggct ggtacacact tgccaacact tcttcatccc gtatttacct aaaacaagcc
    42421 ttccaagaaa atagcaacct cctagagcaa gtggtagaac ccttgactat tatcactggt
    42481 ggacacaacc acaaggacca gttgacctat gcttggaaaa cacttttgca gaatgcgcca
    42541 catgatagta tctgtggctg tagcgtggac gaagttcacc gcgagatgga aacgcgtttt
    42601 gccaaggtca accaagtagg aaactttgtt aaaagtaatt tgctcaacga gtggaagggt
    42661 aaaattgcta cggataaggc tcaaagtgac tatctcttta ctgtcattaa cacaggcttg
    42721 catgataagg tcgatactgt cagcacagtg attgatgtgg cgacttgtga tttcaaggaa
    42781 ttgcacccaa cagaaggcta caaaaagatg gctgctctta tcttgccaag ttaccgtgtg
    42841 gaggacttgg atggtcgtcc tgtagaggct acaatcgaag acctcggagc taattttgaa
    42901 tacgatttac caaaagataa gttccgccaa gctcgtattg ctcgacaagt gcgtgtgacc
    42961 attctagttc acctagcacc gctttcttgg acaaccttcc aattgctgga aggaaaacaa
    43021 gaacaccgtg agggtattta ccaaaacgga gtgattgata caccattcgt aacggtgagt
    43081 gtggatgaca acatcacagt ctatgacaag acaactcacg aagcctatga agactttatc
    43141 cgctttgaag accggggtga catcggaaac gagtatatct atttccaacc aaaaggaaca
    43201 gagccaatct ttgcagagct taagggccac gaggtcttgg aaaacacaga tcgctatgct
    43261 aaaatcttgc tcaaacatga attgaccgtg cctgtcagtg cggatgaaaa gctagaagaa
    43321 gagcaacaag gtatcatcga gtttatgaag cgtgaggctg gacggtcaga agaattgaca
    43381 aacattcctc tggaaactga gttgactgtc ttcgttgaca atccacaaat ccgcttcaag
    43441 actcgcttta ctaacactgc caaggatcac cgtatccgtc tcttggtcaa gactcataac
    43501 acgcgtccaa gcaatgattc tgaaagtatc tatgaggtgg tgacacgacc aaacaaacca
    43561 gctgcttcat gggaaaatcc tgaaaatcct caacaccaac aagcttttgt cagtctgtat
    43621 gacgatgaaa aaggggtgac tgtatccaat aagggattga atgaatacga aatccttggg
    43681 gataacacca ttgccgtgac cattttgcgt gcatcaggtg agctaggtga ctggggctac
    43741 ttcccaacgc cagaagcaca atgcttgcgg gagtttgaag tcgaatttgc gattgaatgc
    43801 caccaagccc aagaacgctt ctcagcctat cgtcgtgcca aagccttgca gacaccgttt
    43861 accagccttc agcttgctag acaggaagga agcgtggttg cgactggtag cctcttgagc
    43921 cattctgttc tcagcatacc gcaagtttgt ccaacagcct ttaaagtggc ggaaaatgaa
    43981 gaaggctatg tcctccgtta ctataatatg agtcaagaaa atgtgcgcat atcagaacat
    44041 caacaaacca ttcttgactt acttgagcga ccatatccag ttcattcagg actattggct
    44101 ccacaagaaa ttcgtacaga attgattaaa aaagaagaaa tctaatttca aaaagtaaac
    44161 ataaagagaa aggaggggcg aaagagtaag aactaactgc tgattcgccc ctttttatgg
    44221 taaaaacaat gaccattgca acgattgata tcggagggac tggaattaag tttgccagtc
    44281 tgactcctga tggaaaaata ctgaataaga caagcattcc aacgcctgaa agcttggagg
    44341 atttactagc ttggctagac cagcgcttgt cagagcagga ttacagtggg attgctatga
    44401 gtgttccagg tgcggtcaat caagagacag gtgtgattga tggcttcagt gcggtgccct
    44461 acatccatgg cttttcttgg tatgaggcgc ttagctctta tcagattcct gtccatctgg
    44521 aaaatgatgc caactgcgtt ggactcagtg aattactggc tcatccagaa cttgaaaatg
    44581 cagcctgtgt cgtgattggg acagggattg gtggagctat gattatcaat ggcagactgc
    44641 accgaggtcg ccacggcttg ggtggagaat ttggctatat gacaaccctt gcccctgctg
    44701 aaaagctcaa caactggtcg caactagcgt caactgggaa tatggttcgc tacgtgattg
    44761 aaaaatctgg tcagactgat tgggacggtc gcaagattta ccaagaagct gcagctggga
    44821 atgccatttg ccaagaagcc attgagcgca tgaaccgcaa tttggcgcaa ggcttgctca
    44881 atatccagta tctgattgat ccagatgtca tcagtctggg aggctctatc agtcaaaatc
    44941 cagattttat tcaaggtgtc aagaaggctg ttgaagactt tgtcgatact tacgaagaat
    45001 atacggtcgc acccgttatc caagcctgca cctatcatgc agatgctaat ctctacggtg
    45061 cccttgtcaa ctggctacag gaggaaaacc aatggtaaga tttacaggac ttagttccaa
    45121 acaagcgcaa gctattgaag tattaaaaaa tcacatttct ctgccagatg ttgaagtggc
    45181 tgttactcag tctgaccaag cctctatctc tatcaagggt gagggtggcc actatcaatt
    45241 gacctatcgc aaacctcacc aactttatcg tgccttgtcc ttgttggtaa cagttctagc
    45301 agaagctgat aaagtagaga ttgaggaaca agcagcttac gaagatttgg cttacatggt
    45361 tgactgttct cgaaatgcgg tgctgaatgt ggcttctgcc aagcagatga ttgaggtctt
    45421 ggctctcatg ggctactcaa cctttgagct ttacatggaa gacacttacc agattgaagg
    45481 gcagccttac tttggctatt tccgtggagc ttattcagca gaggagttgc aggaaatcga
    45541 agcctatgct caacagtttg acatgacctt tgtaccatgc atccagacct tggcccacct
    45601 gtcagccttt gtcaaatggg gtgtcaagga agtgcaggag ctccgtgatg tagaggacat
    45661 tcttctcatt ggcgaagaaa aggtttatga cctgattgat ggcatgtttg ccacgttgtc
    45721 taaactgaag actcgcaagg tcaatatcgg gatggacgaa gcccacttgg ttggtttggg
    45781 acgctacctg attctgaacg gtgttgtgga tcgtagtctc ctcatgtgcc aacacttgga
    45841 gcgcgtgctg gatattgctg acaaatatgg tttccactgc cagatgtgga gtgatatgtt
    45901 cttcaaactc atgtcagcgg atggccagta cgaccgtgat gtggaaattc cagaggaaac
    45961 tcgtgtctac ctagaccgtc tcaaagaccg tgtgactctg gtttactggg attattatca
    46021 ggatagcgag gaaaaataca accgtaattt ccgcaatcat cacaagatta gccatgacct
    46081 tgcatttgca gggggagctt ggaagtggat tggctttaca cctcacaacc attttagccg
    46141 tctagtggct atcgaggcta ataaagcctg ccgtgccaat cagattaaag aagtcatcgt
    46201 aacgggttgg ggagacaatg gtggtgaaac tgcccagttc tctatcctac caagcttgca
    46261 aatctgggca gaactcagct atcgcaatga cctagatggt ttgtctgcgc acttcaagac
    46321 caatactggt ctaacggttg aggattttat gcagattgac cttgccaacc tcttaccaga
    46381 cctaccaggc aatctcagcg gtatcaatcc caaccgctat gttttctatc aggatattct
    46441 ttgtccgatt cttgatcaac acatgacacc tgaacaggac aaaccgcact tcgctcaggc
    46501 tgctgagacg cttgctaaca ttaaagaaaa agctggaaac tatgcttatc tctttgaaac
    46561 tcaggcccag ttgaatgcta ttttaagtag caaagtagat gtgggacgac gcattcgtca
    46621 ggcctaccaa gcggatgata aagaaagttt acaacaaatc gccagacaag aattaccaga
    46681 acttagaagc caaattgaag acttccatgc cctctttagt caccaatggc tgaaagaaaa
    46741 caaggtcttt ggtttggata cagttgacat ccgtatgggc ggactcttgc aacgcatcaa
    46801 acgagcagaa agccgtatcg aggtttatct ggctggccag cttgaccgca tcgacgagct
    46861 ggaagttgaa atcctaccat ttactgactt ctacgcagac aaggacttcg cagcaactac
    46921 agctaaccag tggcatacca ttgcgacagc gtcgacgatt tatacgactt aatactcttc
    46981 gaaaatctct tcaaaccacg tcagcttcca tctacaacct caaaacagtg ttttgagcag
    47041 cctgcagcta gcttcctagt ttgctctttg attttcattg agtataaaaa caagaacacc
    47101 ttgcttggcg cagggtgttt cgcgtgaaac agaagaatta tctggtttca aatgctacag
    47161 ttaaaattag taaaacaaga aatagaagct gaaaagccag catctgtaga agcttggatc
    47221 atttccgtca aattaaaaaa ggttgctacc gacatatata gattccaaaa acaaaaacgt
    47281 tagcggaact agcagatgtg attttatgga gtttcgattt tgtaaatgat catgctcatg
    47341 catttttcat ggataatgtt gagtggagtc atgcagattc ttactttctt agctttgtta
    47401 gtgacgatgt tgaagaacgt tacatagaaa atgtctatct ggatagccta agtgtcaaac
    47461 aaaaatttaa gtttattttc gacttcggtg atgaatggcg ttttgaatgc taagtgctga
    47521 gagaaatcga gacagaggac gaagaagctt atctcgtacg ttcggttgga acgtcgccag
    47581 aacaatatcc agattatgat ggttttgact attaagaatg gtaaaattga aatcagtctg
    47641 tgtaggctta gtatttcaat agacttcctg caaaactaga atcctagttc atgattgata
    47701 atgccagcaa tcaaattcat tcgtaatccg aagtgtttac gatgatttcg ataggttgtt
    47761 gaaatcattt taaacgtttt tactttggca aagatgttct cagccttgct tctctccttg
    47821 gatagcgcat ggttataggc tttatcttca gctgttagcg gcttgagttt gctggattta
    47881 cgtggagttt gtgcttgaga atatatcttc atgagccctt gataaccact gtcagccaag
    47941 attttaccag cttgtccgat atttctgcaa ctcattttga acaacttcat atcatgacaa
    48001 tagttcacag tgatatccaa agaaacaatt ctcccttgac ttgtgacaat cgcttgagcc
    48061 ttcatagcgt gaaatttctt tttaccagaa tgattcgcta attgtttttt tagggcgatt
    48121 gatttttact tccgtcgcat caatcattac cgtgtcctca gagctgagag gagttcttga
    48181 aatcgtaaca ccactttgaa caagagttac ttcaacccat tagctccgac ggattaagtt
    48241 gctttcgtgg ataccaaaat cagccgcaat ttgttcataa gtgcggtatt ctaggcttaa
    48301 tttaggtttt cgtccacctt ttgcgtgttt aagttgataa gctgttttta atacagctaa
    48361 catctcttta aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg tatcagttaa
    48421 ttgtttactt gcttcataat ttcgcaggga gtctattgac tctttggtag gggtcaatgt
    48481 ttttttcatc tatcccgaga attattttcc cgccatttgt atttgcaaat gctgagtagg
    48541 tttcccagaa agactctgga agattgtttt tagctttttt gtattctaaa tcaacccctt
    48601 caaattttaa gtccatattt ttcctttaca tctgtttttt gtggttctgg tatttgttca
    48661 agttgagtga taatatagcg aattgaattt cgagagtttt tactcagtta atttcttttt
    48721 taacccactt taatttcttt tttaacacgg gttaaaaaag aaattaaagt gggttaattt
    48781 ttcttgactt aaaatttaaa aatgatatac tgtgtttatg gagagatgac aatttataaa
    48841 atgtactact ctattctact agataatgat tgaataaaac tttttataac aacggctagc
    48901 aaagttataa ttttatatct attagaaaat aaatatgtaa ggaaatttaa atgaaaaaaa
    48961 ctacaatatt atcattaact acagctgcgg ttattttagc agcatatgtc cctaatgaac
    49021 caatcctagc agatactcct agttcggaag taatcaaaga gactaaagtt ggaagtatta
    49081 ttcaacaaaa taatatcaaa tataaggttc taactgtaga aggtaacata ggaactgttc
    49141 aagtgggtaa tggagttact cctgtagagt ttgaagctgg tcaagatgga aaaccattca
    49201 cgattcctac aaaaatcaca gtaggtgata aagtatttac cgttactgaa gtagctagtc
    49261 aagcttttag ttattatcca gatgaaacag gtagaattgt ctactatcct agctctatta
    49321 ctatcccatc aagcataaaa aaaatacaaa aaaaaggctt ccatggaagt aaagctaaaa
    49381 ctattatttt tgacaaaggc agtcagctgg agaaaattga agatagagct tttgattttt
    49441 ctgaattaga agagattgaa ttgcctgcat ctctagaata tattggaaca agtgcatttt
    49501 cttttagtca aaaattgaaa aagctaacct tttcctcaag ttcaaaatta gaattaatat
    49561 cacatgaggc ttttgctaat ttatcaaatt tagagaaact aacattacca aaatcggtta
    49621 aaacattagg aagtaatcta tttagactca ctactagctt aaaacatgtt gatgttgaag
    49681 aaggaaatga atcgtttgcc tcagttgatg gtgttttgtt ttcaaaagat aaaacccaat
    49741 taatttatta tccaagtcaa aaaaatgacg aaagttataa aacgcctaag gagacaaaag
    49801 aacttgcatc atattcgttt aataaaaatt cttacttgaa aaaactcgaa ttgaatgaag
    49861 gtttagaaaa aatcggtact tttgcatttg cagatgcgat taaacttgaa gaaattagct
    49921 taccaaatag tttagaaact attgaacgtt tagcctttta cggtaattta gaattaaaag
    49981 aacttatatt accagataat gttaaaaatt ttggtaaaca cgttatgaac ggtttaccaa
    50041 aattaaaaag tttaacaatt ggtaataata tcaactcatt gccgtccttc ttcctaagtg
    50101 gcgtcttaga ttcattaaag gaaattcata ttaagaataa aagtacagag ttttctgtga
    50161 aaaaagatac atttgcaatt cctgaaactg ttaagttcta tgtaacatca gaacatataa
    50221 aagatgttct taaatcaaat ttatctacta gtaatgatat cattgttgaa aaagtagata
    50281 atataaaaca agaaactgat gtagctaaac ctaaaaagaa ttctaatcag ggagtagttg
    50341 gttgggttaa agacaaaggt ttatggtatt acttaaacga atcaggttca atggctactg
    50401 gttgggttaa agacaaaggc ttatggtatt acttaaatga atcaggttca atggctactg
    50461 gttggtttac agtttctggt aaatggtact atacctataa ttcaggagat ttattagtaa
    50521 acacgactac acccgatggc tatcgagtca atgctaacgg tgagtgggta ggataggtat
    50581 ccattagcta aatctaatca ttctgaacta aaaaatcttc ttacatatgt aggaagattt
    50641 tttggattct caaaactagt ttaaaagact acgctattta aaccaatttt aagaatggat
    50701 atataaggat attcagaaat ctagttggtc aacttttgta ttttgaatat accttagatg
    50761 gtgacgatgt cttggtatat ctggtactca cttacatatt ctaacttatt ttaactaaga
    50821 tacaactgta gttggtgaat ttgctacaaa tagtgtagag gcgttatttg aaaaatatac
    50881 aaaaaaggaa ccccaactta catttgagtt cctcttgctt ttaattgtcc gaatccgtat
    50941 tcttatttca aaaaaggtag tgaaaaaggt agtcattcga atgatttccc ttgcaatata
    51001 gtgaaattaa caaaaagaaa aaacgctgat caagcgtttt tcttctgtat tgattcgtat
    51061 tgaatgctta cttaacttct gtaaacacaa cgtgtttgcg aagttttggt gagtatttct
    51121 tcaattgaag gcggtctgga gtgttacgtt tgtttttaga agtaaggtac aagcgttcac
    51181 cagattcttt gtgttcaagt gtaatattta cgcgcatggt atctcccttc tattattcag
    51241 ctgatgcagc tttagcgatt ttacgtcctt tgtagtatcc tttaagtgat acacggtgag
    51301 aacgtgagta atctccagta gtttcgtcaa agtttacaga tggagctgtt actttgtagt
    51361 gtgtacgacg tttgtttttc ttcgcttttg aagtgcgacg tgcaggtact gccattttga
    51421 tttctccttt aggtatttat attcgattca atctactgat tttcatcaac catactagga
    51481 taacacattt tttttgtaaa gtaaagttac ttgacaaaaa aagatgaaaa aattctccta
    51541 tccgacacgg cagacaggag aaggtgttaa atatcaatct caaatggttc gtcaatggtt
    51601 tctgatacgt attttccgtc tttcttccgt tgcttgacac actctgtgag gagatattcg
    51661 atttgcccat tgactgaacg aaagtcgtct tctgcccatg atgcgagtgc agcgtataac
    51721 tttgttgaga gtcgaagggg gatctgcttt tttttagctt cagccatctt tagtaaaggc
    51781 ttcctgtgtt gacaattggt tgtgcatcat gattgccaca aagaacgaca aggagatttg
    51841 aaaccatggc agcttttcgt tcttcgtcaa gttctaccaa ttccccttca ttgagccgtt
    51901 ctagtgccat ttcaaccatt cctacagcac catctacaat catcttccgt gcatcaataa
    51961 tggcagatgc ttgttggcgt tgaagcataa cggcagcaat ttctggagca taagctaggt
    52021 aagtgatacg tgcttcaagg atttccaagc cagcatcctc aacacgactt tggatttctt
    52081 cacgaatacg gttagcaaca atttcgctag agccacggag actaccttca tctgcttgcc
    52141 catcacccgt agtatccaca ttaggagaca catcgtaagg atagatgcgg acaatattac
    52201 ggagggcgct atcacattgc aatgaaagat attctttgta gttatcaacg ttgaagactg
    52261 ccttagcggt atcgacaact ctccaagtta ccgcgatacc gatttctaca gggtttccta
    52321 agcaatcatt gattttttga cgagaattgc tcaaggtcat gactttgagg gaaatctgtt
    52381 tcttgccaat ttcaagattt acatcattgt catttgatga tttagctcct aaaaaaggag
    52441 attttgtgct aacatcacca ctttgtccaa gtcgagtgtg gtttgcaggg ttgactgcta
    52501 cgctgaaggg attgacaaag taaaagccag gttctttgat ggtacctgta tagttaccaa
    52561 agagtgtcag aaccagagct tcttgaggtt tgacaacttt taaaccagca tgagctagac
    52621 ctgcaattac gattagtaaa ggtccgataa taattccaaa aatgttttcc gaaccaaccc
    52681 ccattataaa tataaagata ccaagtacga ttgtcaactc aatgagaatc aatgcgaata
    52741 caccatttgg ttttgaattg attagttttt cagtcataag aatgacctcc tgttatttga
    52801 tatctaaatg atatcacttt aatttataaa gtcaatagaa agttgaaaaa taatcactaa
    52861 aaactttcag cccaataatt tcttttaaaa ggtgagatta tattgtgctc aaatactctt
    52921 ttattcttat aatttttaca ctataattgt agttagaaag gaagagaaat gtttgattat
    52981 agagcactag ttattttgat gactttgatg gatcattgtg agctatcatt atatgaatta
    53041 tctgttaagg tgagcttacc tataaaggaa gtcaaagaag gaatagatta tttagtgcct
    53101 tatctagcta ataaagggat agtgctggat aaaaagcaag gtcgctatag tttatcaaat
    53161 cgtacgaagc agtctttgac agatattatt aagtcggatg aattggtttt accaaagtcg
    53221 actcgcttag ctttaatcta tctttacact ttttgccgat tagattttat atcgaataat
    53281 cattaccaag actttttgaa agtaagtaag aatacaacct tatctgatat tcaatcatta
    53341 agaaagatta tgttagataa tgatttggag ctagggtaca gtagagcaaa aggttatact
    53401 ttacacggtt cagagtggaa taagcaccgc ttagcttttc aaatggttag tgagttgctg
    53461 gaatcctcca tagggatttg gggtttggat tatgttttat ccagttgggg gtattcatta
    53521 acttatgatt tgattgatca ggtagttaaa gattattatg agaagctaca gctagtacct
    53581 attgttaatc aattaaaagt ttaccttttc ggtttagtat tcattctgtg taggtatcaa
    53641 agggatgttg aaagagtatg tctttcagag acattagtat ctcctgttat tcaagatata
    53701 accactattt tattggatac agtggttgat ttgggaatta tagatacggt gttttctgag
    53761 gatgattatc gctatatcac cgttttatta tcaagttgct ttgaaggtga agtagatgtt
    53821 gctccggttt actttaatca attaacagag gctattataa gtagaatgga agatatttct
    53881 ttgttacatt ttaaacaaag ggaaggattg agagaaaatc ttcgccgcca ccttataccg
    53941 gcttactata gattaaagtt cggcctacct agttcaaatg aatatgtatt gcatgttaaa
    54001 gaacattatc ctgatttatt tgaattagtc aaagattctt tgatgccctt gatggacgct
    54061 attgacaatc ccatacctga tagtgaaaca gcatattttg ttatccattt cggaggttat
    54121 ttaaagaaag cagatacttt gcctcaaaaa tggtataaag cagcaatcat ttgtcctaat
    54181 ggtgttagtt cttcattgat gttaaaagag aatctattag cattatttcc tcaaattgag
    54241 tttataggaa cctcaaagat tgatgattta caggtgaaag ctagtagtga ctatgatatg
    54301 gttttttcta ccataaaggt ggagacagaa aagccaaatt atctagtttc ggttatgatg
    54361 actgaagagc aagcaataca actagtagaa ctagtgttaa aagattttcc gaatttagag
    54421 tatggagatt ttgagattga acaaatcctg aatattgtca aaagatatgg aattattaca
    54481 caagaattgg aattaagatt ggcgttaaag aattatcttt accaaaaaaa tgatagaaag
    54541 gaaattgtac cagtgctaga acaacttatt accaaagaaa cctatcaggt tagttcgcaa
    54601 aaattaggat ggaaggaggc gattcgttta gcagctaaac cgcttttgga tcaagataag
    54661 ataactgaga actaccctga ggcaatgatt caaaaagtag aagagtttgg accttttatt
    54721 aatttaggga agggagtagc aattcctcac gctcggccag atgaaggtgt gaatgaaata
    54781 ggaatgtcaa tgttagtttt ggaagaaccg atttatttat tggataatcc agaacaagag
    54841 gtaagattgt tgatttgtat tgcagccatt gataatgaga gtcatttaaa ggctttgtca
    54901 catttaacaa caattttaag agataaaaat catgttcaaa ctttaatatc atcaaaaaac
    54961 tataatgata ttaaaatgat aattaaacag gaggattaga taatgttaaa aattggtaca
    55021 gcttgtggtt caggattagg ttcaagtttt atggtacaga tgaatattga atctgtattg
    55081 agtgatttga atgtttcgga tgtagaagtt gaacattatg atttaggtgg agcagatcca
    55141 aatgcagctg atatttggat tgttggtcgt gatctagctg attcagctag tcatcttgga
    55201 gatgttcgta tcttaaatag tattattgat atggatgaac tacgagaatt aattactaaa
    55261 ctttgtgaag aaaaaggact tatataggag gctagcgtca tgatgaagtt catattggat
    55321 attgttagta caccagctat tttagtagct ttaattgcaa ttttaggatt agttcttcag
    55381 aagaagaaat tacctgatat tattaaaggt ggaattaaga cctttgttgg tttcttagtt
    55441 gtatctggtg gtgcaggaat tgtacaaaat tctttaaatc catttggtac catgtttgag
    55501 catgcttttc atttatctgg cgttgtgccg aataatgaag caattgtagc tgtagcttta
    55561 acaacatatg gctcagctac tgcaatgatt atgtttgcag gaatggtgtt caatatctta
    55621 atcgctcgtt ttactcgatt taaatatatt tttttaacag ggcaccacac tctatatatg
    55681 gcatgtatga ttgcggtcat tttatcagtt gctggcttta ctagcttgcc tctcatctta
    55741 ctaggaggat tagcactcgg tattattatg agtatttccc cagcatttgt gcaaaaatat
    55801 atggttcaat taactggaaa tgacaaggtg gctttaggtc atttcagttc tttgggatat
    55861 tggttgagtg gttttactgg tagccttatc ggtgacaaat caaaatcaac agaggacatt
    55921 aaatttccaa agagtttagc ttttttacgt gatagtactg ttagtatcac tttatctatg
    55981 gcagttattt acattattgt agctatcttt gcagggtcag aatatataga aaaagaaatc
    56041 agtagtggta caagtggtct agtttatgct ttacaattag caggtcaatt tgcagcaggg
    56101 gtatttgtta ttttagcagg tgttcgcctt attttgggcg aaattgttcc agcctttaaa
    56161 ggtatttcag agcgtcttgt acctaattca aaacctgctt tggattgtcc gattgtttat
    56221 acttatgcac ctaatgcagt tctaattgga tttatctcta gttttattgg tggtttagta
    56281 agtatggtaa ttatgattgc ttcaggaacg gttgttatct taccaggcgt tgtgcctcat
    56341 ttcttctgtg gagcgactgc aggtgttatt gggaatgcat ctggtggtgt tcgtggagcc
    56401 actattggag catttttaca aggtatttta atcagttttc tcccagtctt tttaatgcca
    56461 gttttgggag gactcggttt ccaaggatca actttctcag atgcagattt tggtctatca
    56521 ggaattattt taggaatgtt aaatcaattt ggctcacaag caggcattgt gattggtctt
    56581 gttcttattt tagcagttat gtttggagta tcctttatta aaaagccatc tgcaaaggag
    56641 gaataaggga tgattttaag taaaaataga gaagatgagt taagaaaatt tgcgactaac
    56701 atccgattaa atactcttag aacattgaat catcttggat tcggacatta cggaggaagt
    56761 ctgtctatcg tagaagtttt agcagtgctt tatggtgaaa taatgccaat gactccagaa
    56821 atatttgcag cacgagatag agattatttc atattatcaa aaggtcatgg aggaccagct
    56881 ctatacagta cactctattt gaatggtttc tttgacaaag aattcttata ttctttaaat
    56941 acaaatggaa ccaaattacc gtctcatcct gatagaaatc taacgccagg catagatatg
    57001 acaacgggct ctttaggaca aggaattagt gttgcaactg gacttgcata tggtcagaga
    57061 ataagaaaga gtccctttta tacttacgct attgttggag atggtgagtt aaatgaggga
    57121 caatgttggg aggctataca gtttgcttct catcaacagt tatccaactt aattgtattt
    57181 gttgatgata acaaaaaaca attagatggt tttacaaagg atatttgtaa tccaggtgat
    57241 ttcgtagaaa aattttcagc atttggattt gaatccatta gggtcaaggg ttcagatatt
    57301 agagaaattt atgaagggat tgtccaatta aaacagtcaa ataattcatc acctaagtgc
    57361 attgtattag atactattaa aggtcaaggg gttcaagagc tggaagaaat gaaatccaac
    57421 catcatcttc gccctactgt agaggagaga caaatgttaa cttcagttgt agaaagatta
    57481 agtcaggaat tggaggaaac agaatgatga gaagcacgaa agaattacgg catgtatata
    57541 gagacttcct tttagaggct aatcaaagtt attctgatat agtagtctta gaagccgatt
    57601 tgtcaagttc gatggctact aataatcttg aaaaggactt tggagaccgt tatgtgaatg
    57661 ttgggattat ggaagcagaa atggtcggcc ttgcagcagg cttgtctatt caggggttta
    57721 gaccttatct tcatacattt ggtccttttg cttcacgaag agtatttgat caattattta
    57781 tttctcttgg atacgcacaa ttggatgcca ctgtgattgg atcagatgca ggagtaactg
    57841 cagaaatgaa tggtgggaca catatgccat ttgaagaaat tggattgtta cgtttaattc
    57901 ctaaatcgat catttttgaa gcaactgatg atatccaatt tcgtgaaata ttgaaccaga
    57961 cattagactt aaaaggacta aaatatattc gaacaattag aaaagctcca gttcctgtgt
    58021 atcaaggtgg agaagatttt tctaaaggct acattgagtt aaggcatggt gaagatcttg
    58081 taatcgttgc ttctggtata atggttgctc caagtattcg agttgcagat gaactgtcta
    58141 aattaggtta ttcagtaggt gtgatagatt tatttagaat caaaccgata ccagaacaga
    58201 taaaaacaat gttaagtgga aaaactatat ttactgtaga aaaccacaat cagataggtg
    58261 gaattggcag tgctttatgt gaattattct ctgatgatgg aataacaaaa attcatcgga
    58321 tgggtgttca agaaagattc ggtcaagtag ggaaaatgga ttatcttctt aatgagtatg
    58381 gtttgagtga atcgaatata aaagagaagg ttctagaaat ttataatgca agatagatgt
    58441 taaatacact tatctgaaag aatttctgta aaaattacag tacgttattt aaagaaagcg
    58501 gattaaaaag catattctgg tcatcagaaa gtgcactaat ccgctttgtt gtttttaatt
    58561 ttaaatattt cacatgtgta tagaattttc tgaaaattca agaattttat tctgttcatt
    58621 gcctttaaat tgtgctataa tagtaaaaac tgaaatggga gggataagat gactgaatta
    58681 gataaacgtc accgcagtag catctatgac agcatggtta aatcacctaa ccgtgctatg
    58741 cttcgtgcga ctggtatgac agataaggac tttgaaacat cgattgtggg agtgatttcg
    58801 acttgggcgg aaaatacacc atgtaacatt cacttgcatg atttcgggaa actggctaaa
    58861 gaaggtgtca aatctgcagg cgcttggcct gtacagtttg gaaccattac cgtagcggac
    58921 gggatcgcta tgggaacgcc tggtatgcgt ttctctctaa catctcgtga catcatcgcg
    58981 gactccatcg aggcggctat gagtggtcac aacgtggatg ccttcgtcgc tatcggtggc
    59041 tgtgacaaga acatgcctgg atctatgatt gctattgcta atatggatat cccagctatt
    59101 ttcgcctatg gtggaactat tgcaccggga aatcttgatg gtaaagatat cgacttggtt
    59161 tctgtctttg aaggtatcgg aaaatggaac cacggtgaca tgacagctga ggacgtgaaa
    59221 cgtcttgaat gtaatgcctg ccctggccct ggtggttgtg gtggtatgta tactgctaat
    59281 accatggcaa ctgctatcga agttctaggg atgagtttgc cagggtcatc ctctcaccca
    59341 gctgaatcag ctgataagaa agaagatatc gaagcagcag gacgtgctgt tgttaagatg
    59401 ttggaacttg gtctcaaacc atcagatatc ttgactcgtg aagcctttga agatgctatt
    59461 actgtaacga tggctctcgg tggttctaca aacgccactc ttcacttgct cgccattgcc
    59521 catgccgcaa atgttgactt gtcacttgag gacttcaata cgattcaaga acgtgtgcct
    59581 cacttggccg acttgaaacc atctggtcag tatgtcttcc aagacctcta cgaagtcggt
    59641 ggtgtccctg cggttatgaa gtacttgttg gcaaatggtt tccttcacgg agatcgcatc
    59701 acatgtactg gtaagactgt agctgaaaac ttggctgact ttgcagactt gactccaggc
    59761 caaaaagtta tcatgccact tgaaaatcca aaacgtgcgg atggtccgct tatcatcttg
    59821 aacgggaacc ttgctcctga cggtgcagtt gccaaggtat caggtgttaa agtgcgtcgt
    59881 cacgttgggc cagctaaggt ctttgactca gaagaagatg cgattcaggc cgtcctgaca
    59941 gatgaaatca ttgatggcga tgtagtcgtt gttcgttttg ttggacctaa aggtggtcct
    60001 ggtatgcctg agatgctgtc actttcttca atgattgttg gtaaaggtca gggagataag
    60061 gtggccctct tgacggacgg acgtttctct ggtggtactt atggtctggt tgttggacat
    60121 atcgctcctg aagctcagga tggtggacca attgcctatc tccgtaccgg cgatatcgtt
    60181 acggttgacc aagataccaa agaaatttcc atggccgtat ccgaagaaga acttgaaaaa
    60241 cgcaaggcag aaacaacctt gccaccactt tacagccgtg gtgtcctcgg taaatatgcc
    60301 catatcgtat catctgcttc acgcggagcc gtgacagact tctggaatat ggacaagtca
    60361 ggtaaaaaat aaactcatac ttgaaaatct cttcaaatca cgtcaacgtc gccttgccgt
    60421 aggtatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgggctga
    60481 cttcgtcagt tctatccata acttcaaaac agtgttttga gcaacctgcg gctagttttc
    60541 tagtttgccc tttgattttc attgagtatc aaaaagcaag ccatttttgg cttgcttttt
    60601 tcatctttaa aaatgattgg cctgcttaac gaggtggtag tccaagggca atacggccat
    60661 agcgactgat tcgtgtgatt ttccaagcag gcgaccaggt aacttcaacc ttgatatctt
    60721 tgataccctc gatttgtttc agacctgcca cgatttcaat aggcaggctt tcggcgcaat
    60781 cacaggcagt atcggtgaag gtcatgacaa tcttgcagag ccccgtttca tccagattga
    60841 tttcataaat cagacctaga ttgtaaacat ccaattccac atctgtatca aaaactttct
    60901 ctagtttttc gatgatttgg tcttgcaagg ccaaagcacg gtcattgatt ttgatatcgt
    60961 ctctcatagc agtccctcca cgtgataaat atcctctatt ttctcataat tctgacaatt
    61021 tggcaagttt ttgatgaatt ttctgaaaaa tatgataaaa tgaagaaaat acggaatcaa
    61081 ggggaagtct atggagcaga ttggaaaagt ctttagacaa ttacgagagt caagaaatat
    61141 ctcactgaga caagcaaccg gaggacaatt ttcgccgtct atgttgtccc gttttgaaac
    61201 aggtcagagt gagctttcgg tggaaaagtt tctatttgct ctggaaaata tatctgccag
    61261 tgtggaggag atcctctttc tggcgagagg tttccagtat gatacagatt ctgagttgag
    61321 aaaagaaatt acagatgtct tggaaccaaa gaatatagca cctcttgagg acttatatcg
    61381 cagggagtat caaaagcatg cccattctca caacaaacag aaacatattc taaatgccat
    61441 tattatcaag tcttatatga agagcataga tgaaagggta gagttaacag cagaggaagg
    61501 aaaagtcctt catgattatt tgttttctac cgagatctgg ggaatctatg aactcaattt
    61561 attttcagtc agttctccat ttttatctgt ttctcttttt actagatatg tacgagaaat
    61621 ggtacgtaaa tctgattttc taatggaaat gtctggcaat cgaaaccttt ttcatactat
    61681 actattgaat ggctttttag ctagtattga gtgtgaagaa tttaccaatg cctattattt
    61741 taaacgtgtt atcgaagagc atttctacaa ggaaaatgag acctatttcc gaattgttta
    61801 tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga gtcaaggaag gtcagaaaaa
    61861 gatggaggat gctgtccgta tttttgagat gcttggctgt aataaatctg ccgaatacta
    61921 tagaaatacg accgaatgtt gagtatctgc aaaccaagaa aaaatttgaa gcgatagaac
    61981 tgttgccctc tctcaggtca ttacaaaagt tctatcgttt ttttgctcat tttgtttgtt
    62041 gcatatattc aaaagaatcg tttcgcaaat tcataagtgc tatactaaag ctattcttga
    62101 tgtagaactt agaacaagga gggagattat ctatgaaact attgtttaga aatccagctt
    62161 atagaatttt gactttatca cgcttcttca atgcttttgg tgcttcgatt ttcaacctgg
    62221 tctttatcgt ctatgcatcg accttgtcac aagcatcttt tgctgttgct atggcgaata
    62281 ttgtcatgat tcttccgacc ttctttacag tttttgcagg gattcgggca gattacacga
    62341 gggacaaggt caaatggatg gtctatagcg gtttgtttca ggcggttcta ttttttctag
    62401 cagccctagt tgttcagcaa gctagtctct ttgccttttc tagcctgtgt ttgatcaatg
    62461 tcattagtga tatcatcagt gattttgcag gtggcctgcg tatgcctctt attaaggaaa
    62521 aagtagctga agatgatctg atggaggctt attctttttc acagttcatc acctatattt
    62581 cagctattgg tggtcaagct ttcggagtct ggctcttagc tctatcggtc aacaattttt
    62641 ctctcgttgc gggaatcaat gcctgctttt tcctagtatc agccactatc ctctttttag
    62701 gaaaaagcaa attgagcctg tcaatgtcat ctgctgatgg tgaaaactta aaaaatgaga
    62761 agttttctat caaagaccag ttcctaacaa tttaccgaaa tttacgtctc gtttttctta
    62821 aaagtggaca gaaaaacttt ggttttatgc tctttgctgt cttgcttatt aattccttgg
    62881 gtggcgcttt gggtggaatt tataatatct tctttttgag ccattctctc ttgaattttt
    62941 cttatacaga ggcactattt atcaatcaat tctgtgtttt agtagcaatc atcatcagta
    63001 gccttacggg caatgattat tttgggaagc agtccttgcc tagattgatg atgtgggcga
    63061 ccgtaggact tagtctagtt ggtttggcta atttattcaa tcaagtcgtg cttggtttgc
    63121 tatttctctt ctttactctg tatgtgtctg gtaaagttca accaaagatt agtgccatgc
    63181 tcatgaaaaa tctagctcca gaggttctag ctcgtactag taatttttta gatctattgt
    63241 ttaccttatc catacctgtg ggaacagctt gtttttcact agtagccgta tggaacatgc
    63301 agttgacttg gatgctattt gttggtcttt ccttgctagc tattttttta acaattctta
    63361 atctcaaaaa tgatatctaa atcctaattt ttttctcact gttttaatcc ctctatttat
    63421 ggtaaaataa gactattaag tttaaagagg attccctatg aaattacaaa aaccaaaagg
    63481 aacgcaggat attttacctg ctgaatctgc caagtggcag tacgttgagg gctttgcccg
    63541 tgaaattttc aaacgctaca actacgcaga agtgcgtacg cctattttcg agcattacga
    63601 ggttatcagc cgctctgtcg gagatacaac agatattgta accaaggaaa tgtacgattt
    63661 ctatgacaag ggtgaccgcc atattaccct tcgtccagaa ggaactgcgc ccgttgtccg
    63721 ttcctatgtg gaaaataaac tcttcgcccc agaagtgcaa aagccaagca agttctacta
    63781 catgggacct atgttccgtt atgagcgtcc acaggcaggg cgcttgcgcc aattccacca
    63841 gattggtgtt gagtgttttg gctctagcaa tccagctacc gatgtggaaa caatcgctat
    63901 ggcagcccat tttttgaagg aaatcggtat tcaaggtgtc aaattgcacc tcaacactct
    63961 tggaaatcct gagagccgtg cagcctaccg ccaagccttg attgactatt tgacaccgct
    64021 caaggagacc ttgtctaagg atagccaacg tcgcttggag gaaaatcctc ttcgtgtctt
    64081 ggactctaag gaaaaagaag acaaggtggc agtagagaat gcgccgtcta tcttggactt
    64141 tcttgatgaa gaaagccaaa ctcattttga tgctgtgcgt cagatgttgg aaaatcttgg
    64201 agtagattac atcatcgata ccaatatggt gcgtggtctg gactactaca accacaccat
    64261 tttcgagttt atcacagaga ttgagggcaa tgacttgaca gtctgtgcgg gtggtcgcta
    64321 cgatggtttg gttgcttact ttggaggccc tgaaactgct ggatttggtt ttgggcttgg
    64381 tgtagagcgt ctgcttctca tccttgaaaa acaaggcgtg gccctcccta tcgaaaatgc
    64441 cctagatgtc tatatcgcag tcttgggtga tggagcaaat gtcaaagccc tagaactagt
    64501 ccaagccctt cgccaacaag gtttcaaagc agagcgtgat tacctcaacc gtaagctcaa
    64561 agctcagttc aagtcagccg atgtctttgc gactaagacc ctcatcaccc tgggagagag
    64621 cgaagtcgaa agcggacaag tgacggtcaa gaacaaccaa acccgagaag aagtgcaagt
    64681 gtcacttgag acaatcagcc aaaacttctc agaaatcttt gaaaaactag gattttatac
    64741 tcaataaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acactgtttt
    64801 gaggttgtag atgaaactga cgaagtcagt aaccatacct acggcaaggt gaagctgacg
    64861 tggtttgaag agattttcga agagtattaa tgatagataa agtggtcagg aacttactcc
    64921 tgaccttttt cttttgcaaa atgacaaaaa tcataaactt tttgacaact atacttgtca
    64981 aaaagaaaaa gatgtgttac aatgtaagca agttaagaga aaagaggaaa ggagctatga
    65041 tgtgggtact agggtttata ctatttctga ttttctttta ttctaatgat tctaaaaaaa
    65101 tcaagaaact agagaagaaa atcaaaagac ttgagcgaaa agagaaagga aacgcagcaa
    65161 tgtcgagatt attacaagaa atgattggaa aggaaccaat tataacggga gtgtatattg
    65221 ggccagataa ctgggaagtt gtggatgttg atgaggaatg ggtcaaacta cgtagtgttg
    65281 ataatacggg aaaagaaaaa ttcaagttgc aacgtattga agatatccaa accgttgaat
    65341 ttgacggaga gtaggtgtgt aacgtgcaac taaaaaatcg tctaaaagag cttcgagctc
    65401 gcgatggtct caatcaaacc gacctagcca aactggcagg ggtttccaga cagaccatta
    65461 gcctactaga acgggatgag tacaccccat ccattatcat tgccctgaaa atatctcaaa
    65521 ttttcaacga aacagtcgaa tcggtatttc gtttggagga ggacgagtga tgaacaagta
    65581 taaagtgatt tattatgtag tggtcatagc tttattagtc agcgtatttc tactgattgg
    65641 gatggaccta agctggttta atccctatca aagcgaccaa tttgtttggg tctactttgc
    65701 tctcatccca gtaactgaat ggattgaaaa gaaatccaaa aatctagcaa gtgaaaaagg
    65761 agaatgaata tgaaaaagaa acgtagattg ttatttttga tgtctattgt cttggggggg
    65821 ttcttgggca tgtttgtagg gatgtttaag gcacgtgtcg aatcccacga aattatttta
    65881 gatgtaaaag ccttgatgcc atggatatca gctatttgtt tactgatagg tttcattagt
    65941 atgtttttga ctttcaattt cttaaagaaa agcagaaaat ttcattcctt gtatcaagag
    66001 gaaatggatg acgatctgaa tgaaacctat tatgtgcaaa tgtatcggaa tcttgagttt
    66061 ggaactattg cttttaatat tacaggtgta gcgattccat tggctatttt tatttcatta
    66121 agtgaggtga ttatattgca tacaaaccct caaacatttt tcctttcttt cttactcttt
    66181 gtggtattct tagtcgctca aaaatctctt tttaaaacca ttgcgattgt tcgtcagttt
    66241 gatttggaat ttttcgctac accaaaggat gtcttgaact atataaattc ttatgatgaa
    66301 ggggagcgtc aggctaattt ggaacagagt tttcgaattt tattccaatt acaccaatat
    66361 gtcttaccag ccttatatat ttttcttatt atcatttctt tcttgacagg agagattcag
    66421 ttactagctt tcttgcttgt aggagccatc catgtttata tcaatgtgat gcagttacct
    66481 atggtaaaac gttatttcaa ataaaggagt tatctatgaa actacttaaa aaccttggct
    66541 ggtttcttct agcccttcta tcctttttct ttatctatgg ctttattcag gggctcgcga
    66601 ctgcgtcgct tgctttaggc gcttcaccct atgctgttac tctactatat gtggtcttgg
    66661 ctggagtata tgtgtacggc atttacaaat ggtatcagaa agctcctgtt tatattgaga
    66721 agagcggctt taaccgattt atttggcttc ctgccttggt ttggttctta tctctgggcg
    66781 ttcaattctt cttgccagat gatccttcag taaatcaaca aatagcgaca gacttgacct
    66841 tgtctcaacc acttttctca ttctttgctg tggttatttt tgctcctttg acggaagaga
    66901 ttgtttttag agggatgtta gcacgctatc tctttcctaa gcaggacaat agtaaacgaa
    66961 ccctgatttt tcttctggta tctagtcttc tatttgcctt gattcatttt ccaggtgatg
    67021 tgcaacaatt ttttgtctat tttagccttg gttttagttt gggtttggct tacattagca
    67081 gaaaaggtct ggtctacagt atttctcttc acgctttgaa taatttagtc ggctttttga
    67141 tgattctcat gctataatag agtcaggagg tcacatgaaa cgagtaattt tattagcagt
    67201 gattcaggca gtcgttctat ttttcatcat tggagcgcta gcttatgcct tcaaaggcga
    67261 tttcttctat aactatctag cagttgtctt tgctcctatt gcaggtgtac tgcgttttgg
    67321 gacggcttac ataacggaaa ttgtcttgcc tcgaaaggca gctgaaatcg ctgaaaagcg
    67381 taaagcaggc aaaaattcaa aataaaagag tccggtgaag ttcatcggat ttttgt
//
LOCUS       DBEJNA010000006        63861 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEJNA010000006 DBEJNA010000000
VERSION     DBEJNA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 63861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.06"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(19..570)
                     /locus_tag="ACL3JB_000429"
     CDS             complement(19..570)
                     /locus_tag="ACL3JB_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685228.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFHSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(560..757)
                     /locus_tag="ACL3JB_000430"
     CDS             complement(560..757)
                     /locus_tag="ACL3JB_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685229.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(761..1555)
                     /locus_tag="ACL3JB_000431"
     CDS             complement(761..1555)
                     /locus_tag="ACL3JB_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685230.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1963..2388)
                     /locus_tag="ACL3JB_000432"
     CDS             complement(1963..2388)
                     /locus_tag="ACL3JB_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685231.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2517..2876)
                     /locus_tag="ACL3JB_000433"
     CDS             complement(2517..2876)
                     /locus_tag="ACL3JB_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0685232.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(2922..3128)
                     /locus_tag="ACL3JB_000434"
     CDS             complement(2922..3128)
                     /locus_tag="ACL3JB_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685233.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3115..3276)
                     /locus_tag="ACL3JB_000435"
     CDS             complement(3115..3276)
                     /locus_tag="ACL3JB_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685234.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3674..4630)
                     /gene="lytA"
                     /locus_tag="ACL3JB_000436"
     CDS             complement(3674..4630)
                     /gene="lytA"
                     /locus_tag="ACL3JB_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0685235.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5006..6376)
                     /locus_tag="ACL3JB_000437"
     CDS             complement(5006..6376)
                     /locus_tag="ACL3JB_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0685236.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFLASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6683..7849)
                     /gene="recA"
                     /locus_tag="ACL3JB_000438"
     CDS             complement(6683..7849)
                     /gene="recA"
                     /locus_tag="ACL3JB_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0685237.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(7904..9160)
                     /locus_tag="ACL3JB_000439"
     CDS             complement(7904..9160)
                     /locus_tag="ACL3JB_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0685238.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(9245..10261)
                     /locus_tag="ACL3JB_000440"
     CDS             complement(9245..10261)
                     /locus_tag="ACL3JB_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0685239.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(10269..10787)
                     /locus_tag="ACL3JB_000441"
     CDS             complement(10269..10787)
                     /locus_tag="ACL3JB_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0685240.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(10777..11220)
                     /gene="tsaE"
                     /locus_tag="ACL3JB_000442"
     CDS             complement(10777..11220)
                     /gene="tsaE"
                     /locus_tag="ACL3JB_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0685241.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(11306..11926)
                     /locus_tag="ACL3JB_000443"
     CDS             complement(11306..11926)
                     /locus_tag="ACL3JB_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685242.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(12309..13172)
                     /locus_tag="ACL3JB_000444"
     CDS             complement(12309..13172)
                     /locus_tag="ACL3JB_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685243.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13361..13531
                     /locus_tag="ACL3JB_000445"
     CDS             13361..13531
                     /locus_tag="ACL3JB_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR0685244.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            13846..14142
                     /locus_tag="ACL3JB_000446"
     CDS             13846..14142
                     /locus_tag="ACL3JB_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0685245.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            14245..16260
                     /locus_tag="ACL3JB_000447"
     CDS             14245..16260
                     /locus_tag="ACL3JB_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0685246.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            16262..16894
                     /locus_tag="ACL3JB_000448"
     CDS             16262..16894
                     /locus_tag="ACL3JB_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685247.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            17035..17313
                     /locus_tag="ACL3JB_000449"
     CDS             17035..17313
                     /locus_tag="ACL3JB_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HGR0685248.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(17822..18235)
                     /gene="ndk"
                     /locus_tag="ACL3JB_000450"
     CDS             complement(17822..18235)
                     /gene="ndk"
                     /locus_tag="ACL3JB_000450"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0685249.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEESLPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(18346..22023)
                     /gene="rpoC"
                     /locus_tag="ACL3JB_000451"
     CDS             complement(18346..22023)
                     /gene="rpoC"
                     /locus_tag="ACL3JB_000451"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0685250.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMSYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(22056..25667)
                     /gene="rpoB"
                     /locus_tag="ACL3JB_000452"
     CDS             complement(22056..25667)
                     /gene="rpoB"
                     /locus_tag="ACL3JB_000452"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0685251.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFIDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            26083..26153
                     /locus_tag="ACL3JB_000453"
     tRNA            26083..26153
                     /locus_tag="ACL3JB_000453"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26115..26117,aa:Cys,seq:gca)
     gene            complement(26351..27682)
                     /locus_tag="ACL3JB_000454"
     CDS             complement(26351..27682)
                     /locus_tag="ACL3JB_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0685252.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(27973..28797)
                     /gene="endA"
                     /locus_tag="ACL3JB_000455"
     CDS             complement(27973..28797)
                     /gene="endA"
                     /locus_tag="ACL3JB_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0685253.1"
                     /translation="MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(28836..29024)
                     /locus_tag="ACL3JB_000456"
     CDS             complement(28836..29024)
                     /locus_tag="ACL3JB_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0685254.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(29017..30300)
                     /gene="murA"
                     /locus_tag="ACL3JB_000457"
     CDS             complement(29017..30300)
                     /gene="murA"
                     /locus_tag="ACL3JB_000457"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0685255.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(30324..30554)
                     /locus_tag="ACL3JB_000458"
     CDS             complement(30324..30554)
                     /locus_tag="ACL3JB_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0685256.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(30612..31649)
                     /locus_tag="ACL3JB_000459"
     CDS             complement(30612..31649)
                     /locus_tag="ACL3JB_000459"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0685257.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(31633..32121)
                     /gene="coaD"
                     /locus_tag="ACL3JB_000460"
     CDS             complement(31633..32121)
                     /gene="coaD"
                     /locus_tag="ACL3JB_000460"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0685258.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(32111..32650)
                     /gene="rsmD"
                     /locus_tag="ACL3JB_000461"
     CDS             complement(32111..32650)
                     /gene="rsmD"
                     /locus_tag="ACL3JB_000461"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0685259.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32715..33707)
                     /gene="asnA"
                     /locus_tag="ACL3JB_000462"
     CDS             complement(32715..33707)
                     /gene="asnA"
                     /locus_tag="ACL3JB_000462"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0685260.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(33818..34501)
                     /locus_tag="ACL3JB_000463"
     CDS             complement(33818..34501)
                     /locus_tag="ACL3JB_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGR0685261.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(34557..35297)
                     /locus_tag="ACL3JB_000464"
     CDS             complement(34557..35297)
                     /locus_tag="ACL3JB_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0685262.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            35331..35609
                     /locus_tag="ACL3JB_000465"
     CDS             35331..35609
                     /locus_tag="ACL3JB_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0685263.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            35687..36613
                     /gene="yidC"
                     /locus_tag="ACL3JB_000466"
     CDS             35687..36613
                     /gene="yidC"
                     /locus_tag="ACL3JB_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0685264.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(36688..37482)
                     /gene="pflA"
                     /locus_tag="ACL3JB_000467"
     CDS             complement(36688..37482)
                     /gene="pflA"
                     /locus_tag="ACL3JB_000467"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0685265.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(37608..38858)
                     /locus_tag="ACL3JB_000468"
     CDS             complement(37608..38858)
                     /locus_tag="ACL3JB_000468"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0685266.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(38925..39752)
                     /gene="purR"
                     /locus_tag="ACL3JB_000469"
     CDS             complement(38925..39752)
                     /gene="purR"
                     /locus_tag="ACL3JB_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0685267.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(40019..40960)
                     /locus_tag="ACL3JB_000470"
     CDS             complement(40019..40960)
                     /locus_tag="ACL3JB_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0685268.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVAHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(40950..42206)
                     /gene="rmuC"
                     /locus_tag="ACL3JB_000471"
     CDS             complement(40950..42206)
                     /gene="rmuC"
                     /locus_tag="ACL3JB_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0685269.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEAAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(42208..42870)
                     /locus_tag="ACL3JB_000472"
     CDS             complement(42208..42870)
                     /locus_tag="ACL3JB_000472"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0685270.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(42833..43489)
                     /gene="rpe"
                     /locus_tag="ACL3JB_000473"
     CDS             complement(42833..43489)
                     /gene="rpe"
                     /locus_tag="ACL3JB_000473"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0685271.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(43500..44378)
                     /gene="rsgA"
                     /locus_tag="ACL3JB_000474"
     CDS             complement(43500..44378)
                     /gene="rsgA"
                     /locus_tag="ACL3JB_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0685272.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(44380..45252)
                     /gene="rsmA"
                     /locus_tag="ACL3JB_000475"
     CDS             complement(44380..45252)
                     /gene="rsmA"
                     /locus_tag="ACL3JB_000475"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0685273.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(45383..45691)
                     /locus_tag="ACL3JB_000476"
     CDS             complement(45383..45691)
                     /locus_tag="ACL3JB_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685274.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQMVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(45684..46325)
                     /locus_tag="ACL3JB_000477"
     CDS             complement(45684..46325)
                     /locus_tag="ACL3JB_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685275.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(46327..48357)
                     /locus_tag="ACL3JB_000478"
     CDS             complement(46327..48357)
                     /locus_tag="ACL3JB_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0685276.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRIMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEKGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(48434..48730)
                     /locus_tag="ACL3JB_000479"
     CDS             complement(48434..48730)
                     /locus_tag="ACL3JB_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0685277.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(49050..49949)
                     /locus_tag="ACL3JB_000480"
     CDS             complement(49050..49949)
                     /locus_tag="ACL3JB_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685278.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(50021..50581)
                     /gene="rnmV"
                     /locus_tag="ACL3JB_000481"
     CDS             complement(50021..50581)
                     /gene="rnmV"
                     /locus_tag="ACL3JB_000481"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0685279.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(50581..51354)
                     /locus_tag="ACL3JB_000482"
     CDS             complement(50581..51354)
                     /locus_tag="ACL3JB_000482"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0685280.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(51659..52552)
                     /locus_tag="ACL3JB_000483"
     CDS             complement(51659..52552)
                     /locus_tag="ACL3JB_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGR0685281.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(52836..52970)
                     /gene="rpmH"
                     /locus_tag="ACL3JB_000484"
     CDS             complement(52836..52970)
                     /gene="rpmH"
                     /locus_tag="ACL3JB_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0685282.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(53115..54329)
                     /locus_tag="ACL3JB_000485"
     CDS             complement(53115..54329)
                     /locus_tag="ACL3JB_000485"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0685283.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(54485..54778)
                     /locus_tag="ACL3JB_000486"
     CDS             complement(54485..54778)
                     /locus_tag="ACL3JB_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685284.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            54940..55392
                     /locus_tag="ACL3JB_000487"
     CDS             54940..55392
                     /locus_tag="ACL3JB_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0685285.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(55427..56815)
                     /locus_tag="ACL3JB_000488"
     CDS             complement(55427..56815)
                     /locus_tag="ACL3JB_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0685286.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKIVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDMLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            56881..57843
                     /locus_tag="ACL3JB_000489"
     CDS             56881..57843
                     /locus_tag="ACL3JB_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0685287.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(57872..58075)
                     /locus_tag="ACL3JB_000490"
     CDS             complement(57872..58075)
                     /locus_tag="ACL3JB_000490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685288.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(58139..59149)
                     /gene="ccpA"
                     /locus_tag="ACL3JB_000491"
     CDS             complement(58139..59149)
                     /gene="ccpA"
                     /locus_tag="ACL3JB_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0685289.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(59574..60173)
                     /locus_tag="ACL3JB_000492"
     CDS             complement(59574..60173)
                     /locus_tag="ACL3JB_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0685290.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(60175..61272)
                     /locus_tag="ACL3JB_000493"
     CDS             complement(60175..61272)
                     /locus_tag="ACL3JB_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0685291.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGELPAWHLLVDILFVV
                     TYLGVLITKNQRISWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(61272..62009)
                     /locus_tag="ACL3JB_000494"
     CDS             complement(61272..62009)
                     /locus_tag="ACL3JB_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685292.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(62011..62895)
                     /locus_tag="ACL3JB_000495"
     CDS             complement(62011..62895)
                     /locus_tag="ACL3JB_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685293.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(62882..63076)
                     /locus_tag="ACL3JB_000496"
     CDS             complement(62882..63076)
                     /locus_tag="ACL3JB_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685294.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(63073..63279)
                     /locus_tag="ACL3JB_000497"
     CDS             complement(63073..63279)
                     /locus_tag="ACL3JB_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685295.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        18699 a        14357 c        11715 g        19090 t
ORIGIN      
        1 tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac tgttttgagg
       61 ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtatagac cacaattact
      121 caataccgaa tacccctgaa tggtttcttt ttcatgcacc aatatattat aataatcttc
      181 atccaataat aaggctgata aactagcatc ttggtcaaaa tataagggaa tttctcgacc
      241 gtccttcttt aatggatatt ctggtaaaat actaaatagt tcaatcatag aatgaaactc
      301 aggattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac ttccttgata
      361 ctctcccaat tctaaaaagt gattcaaggt agtataaaat tccttatttt ttacttcatc
      421 aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg aatccaatac
      481 gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg caaacatttc
      541 ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt aatatcatat
      601 tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt aaggtcaaat
      661 aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca ttccaaaact
      721 cagatacaaa aggacgatat ttccatatct ctagcatctt tcattttaaa acatgctgag
      781 aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta gtattttcat
      841 ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat agaaggttag
      901 aaacagattt tatctgcttt atatcgccat ctggcaataa aatccgtttt ttgatgggat
      961 taaataaaca tgacacggat tttaagaata attctttctt tgacaccgta tatgtgtaaa
     1021 gcttattttg cttgtttaac caatataaag ctttaaaagt cctcaaacac ctataaattg
     1081 ttgagtttgg aagtccagtg acttgtgaaa gcaaatcaac atttactact ttttgacctt
     1141 ttgtcaataa aaaggcaatc cacgttaatt gttcgctagg tgttaattcc ttagggattt
     1201 cagtatcatt cgcattgagt actagtccca atggagggaa gaagaggttt cccttaaagt
     1261 ctacaaacgg aactctagct tgaagtaatt gctttttttc actgtctgat aacttcgaaa
     1321 acaccaaaac aacatccata ttggcttttt cacccatagt gcgagcctga gtaacaaatg
     1381 aactcaaact cccccttctc ttttctttaa tcaataaaaa tgattcctta tgaaaagtca
     1441 tttgagtata ctcaaacctt tttacaaaac tgattggtaa agtcaaagtc agttcctcaa
     1501 tactgacatc aacataaaag gattgaaaaa ttgacattat ctttttgaca ttcatgtttt
     1561 ttccttattc tatcattttt attatatttt atcattcggt ataataaaat ataagttttt
     1621 tgataaaata accaaaaact actcgctatc ccctctcaca ttaccctaca tatcgtttga
     1681 catgcgactg atagttcagg aaaacttcaa ggagaacttt tctctcatcc actatgcagg
     1741 acttactatt tcacttctac tcctataggc tcaatttgac acttttcttt ttcgaattgc
     1801 tcatatgcct cctgaatagt gagttcgatt tatccaaatt tatttttgtc tattttgatg
     1861 aatacttcca cgaagatagt ctgaaaatga atttgcacca attttccttc tctttttaag
     1921 catattattc cagatatgat tgccctctta ttcagtaata aattacgctt taaacgcttc
     1981 aatcagtata tctcctgttg tcatatgttc taaagaaaat tcttctacat atggtttaac
     2041 atctcttagg ttattacttc ctaatatccc attatgcttt ttcgctaaga aaatagaagt
     2101 cgcttctccc ttaccaataa tcttgttact atcatgattt cttgttaaat ctctatataa
     2161 tgcgtattct tcagttccaa tgtctatgct cacaatctca gctgaaccct tagttaccaa
     2221 ctggtctatc ctagatttta aatggggaat tgtaggtata ttgatttcat catacacctc
     2281 ttgtggaata acaattttac ccaaatagag cttttctaaa agatgttcag tgccaaccca
     2341 taaaaatact gaaatacaat ctgcatcaat aaatacacga ctagtcaaac gacaactccc
     2401 ccctcttcat ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca
     2461 tacttccctt gcgaaattct gttattttct aaaagttgtt cagttgaatt aatatattat
     2521 cctaatgcca tttctttttt actttctgac aaaggacgat ataaacttgt atcatagcct
     2581 aatcttgaag ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg
     2641 tatccatcat tcctcaatct atataacata gctttatgac tgataccata aaactgaccc
     2701 aattttataa tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca
     2761 accatcctat acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt
     2821 ctttcagttt catctccttc accaatcaag ataagactga ctgaactctt cttcacctca
     2881 tcataataaa gatgatacag ttcatgtgct aaagaaaatc tttaccttcc taatggcatg
     2941 tctgaattga ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc
     3001 tttccgagtc cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata
     3061 tctatcggcg attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt
     3121 aaatccattc gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa
     3181 agacaaatac tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat
     3241 tctttttcca acatcacata catttatcac atacatttat cacatacatt tatcacatac
     3301 atttatcaca tacatttatc atattcatac acctctcata aaaagaatag cacactcttg
     3361 tcataatttt ttaaataaaa aaattatgac aaaacaagga agcaatttat tgatgctgct
     3421 taaaaatcta aaattgatga gttcctatca aaaatcgtat cttcaacctc aaaacagtac
     3481 ttaaagctat ccgactcggt ttacattgtc aaatttagat tttatttgag cataactttc
     3541 tagtttgctt tctgattttt gtttaatata gtagcaaaca ttgaaggaaa tatctccaca
     3601 aaaaaacgca tactattaag ctttttcaag acctaataat atgcgctgtt ctgatttgaa
     3661 agacattcca ttattatttt actgtaatca agccatctgg ctctactgtg aattctggct
     3721 tgtctgccag tgttccgtct ggtttgaggt agtaccagcc tgttccgtcc gctgactgga
     3781 taaaggcatt tgataccatg gcgccttctt tagcgtctaa gtagtaccaa gtgtccttgt
     3841 acttgaccca gcctgtcttc atggcacctt cttcgttgaa atagtaccac ttatcagcga
     3901 ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa ccagtaccag ttgccgtctg
     3961 tgtgcttcct ccagcggtct gcaagcatat agcctgaact gtcaaagtag taccaagtgc
     4021 cattgatttt ctcaaacttg tcttttggat aagagccgtc tgagtgtacg taccagtagc
     4081 cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc gttctcaata tcatgcttaa
     4141 actgctcacg gctaatgccc cattttgcca agtaagggta tggatccaca tggtctgagt
     4201 ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt aattccagct aaactccctg
     4261 tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt gcgtaagagt tcgatataaa
     4321 ggcggtagtc cgtcatgaac tcttctttag ttgaatggct ttcaatcagt tcaaccgctg
     4381 cataggtctc agcattccaa ccgcccccaa cgtcccaggc accattatca acaggtccta
     4441 cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa acctaattct gggtctttcc
     4501 gccagtgata atccgcttca ttctgtacgg ttgaatgcgg attcccagtt gagtgtgcgt
     4561 gtacttgcct atatggttgc acgccgactt gaggcaaatc tgttcttaat ttactcacat
     4621 taatttccat attctactcc ttatcaatta aaacaactca ttttttacaa tccagaacca
     4681 gaaactcctt tatttctacc ttacaaagaa gacaatttta gtcacgatta ggcttgtaga
     4741 tagaacttca aaacgcacta ttttgacact gtaaatagga ctgacaaggt ctgcattcta
     4801 tctacaataa caccccaaac taaaaagctt ttcaaaagta tatttttaca gtctctatat
     4861 gtccttttca taaatactat actttattat atcatataaa agaagtcaaa agtctgttaa
     4921 actattttca acaccaaact aaagaagaga acacaagttt tttcgatttt cactagagga
     4981 aatggatttt attcagtaaa tccaactagg attgcacttt ggttgccaaa attgcctttc
     5041 cttcttttat caagggatga cggaatagtg agaagtacag ttgaactgtc atggcaaccc
     5101 agataagagg ttcacaaagg ataacaccct tatatcctgc ccaaggaata atcaaaacca
     5161 caaaaacgat ttttccgatt agttcaataa agctagaaac tagaggaagg atcttttgcc
     5221 ccaagccctg caagcaattg cgataaatca acaagaggct caaaatggga taaaaggctg
     5281 aactgatttg cagatagaga cttccatttt ctatcaagta accatctgtc gaactagcca
     5341 agaaggaaac caaagctgga ctggccaaaa agaggaaaat acaaacaaaa actgcccagg
     5401 atatacttaa acgactgccg attcgaagac cttgaacaat acggtcaggt cgcttagctc
     5461 ctagattctg agaagcaaag gtcgtcattg atgcagaaat agcggtcata ggaagaaggg
     5521 caaaggtcat aatgcgtcga gctgccgtct gggcactaat aatcactgca ccaaatgtat
     5581 taacagaaaa ctgtaaaatc acactgccga tagatacaat tgaactcatc aagcccatag
     5641 ccaaaccttg ctccaagaga tccgcgtaca agcttttgtc ccatttgaaa tgtttaaact
     5701 gtggcaagag ttctggcaca cttttacgaa tataataaaa gcagagaacc gctgataaac
     5761 cttgcgaaat aatggtagca agtcctgcgg attgaactcc cagatgcaat tgcgtaataa
     5821 aatagagatc cagaaccaca ttaaccaagg cagagaaaat cagaaatccc agggctgcta
     5881 gactgtcacc aatagaccgc aacaagcctg caaaaagatt ataagcaaag ctgacaccta
     5941 cacaggtcac aatcatagaa atatattgat aagattgagg aagaatttct gcaggagtat
     6001 ctaagtattg caagagagga tacaagccaa gaaagcccag caacataact agaatgctca
     6061 aaagagcacc taaaatccaa gtggctgcta ctgcttcctt gattttagtg aaattccgag
     6121 ctccataata acgagcaatg acaatcccca tgccattgcc aacaccaagt gtaaaaccta
     6181 caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc caaggattct tgaccaagaa
     6241 atcgtccaac aatcaagaca tcagcagtgt tatagagctg ttgaaaaata tttgatagca
     6301 agattggaaa ggtgaagctt aagagcgagg gaagaatcgg accatgtatc aggtccactg
     6361 ttcgtttttt attcataaag ctattatatc agcttcctag aggagcgaca agaaacagca
     6421 aacttatata tagcggaatg aaataaggac agtcaaatcg atttttaaca atgttttaga
     6481 agtagatgtg tactattcta gtttcgatct attatagttg gttgagtttg gaatagtacg
     6541 ctgtagctgc taaaacattt ctagaaatta atttgacttt cctaataaag ttgttcatat
     6601 cttatttcaa gctactatat ataatctaaa aacttgaatc aaaaatcgaa aaagtagcgg
     6661 atttctccac tgctttaaca gcttattctt caatttcgat ttcaagttca tcgcctaagt
     6721 caagcgtaac ttcttcattc actgcttctt ctttctttgg ctcatctttt ttgttttcag
     6781 tatcttgttc tgaaacttct tctccatcaa tcaagccaaa tttagaacgg acttgcttat
     6841 caatttcatc aaagatttct gggtgctctg ccaagtattt cttagcattc tcagaacctt
     6901 gcccaatttt ttcatctttg taagaatacc aagcccctgc ttttttgata atatccaaat
     6961 cgcttgcaat cttcaaaagc tcaccagtct tagaaattcc ttctccgtac ataatttcaa
     7021 ctacggcttc cttaaacggt ggagctacct tattttttac aaccttaatc ttagtttctt
     7081 taccgacatt ggtttctttt tggtcaccag ttcccttaat ttgtgtatta ccacgaacat
     7141 ccaagcggac tgaagcatag aatttcaaag cacgtccgcc cggtgttgtt tctggatttc
     7201 caaacatcac tccaactttt tcacgcaatt ggttgataaa aatggcaatt gttttggttt
     7261 tattgataga ggcgccaagt ttacgcatgg cctggctcat catacgagcc tgcaaaccaa
     7321 catggctatc tccgatatct ccatcaattt ccgcacgagg aacaagggca gcaactgagt
     7381 cgactacgac aagatcaact gcacctgagt caatcaattt tcccgcaatc tcaagacctt
     7441 gctctcctga gtctggttga gacaagagca attcgtcaat attgacacca agggccgcag
     7501 cataagctgg atcaagggca tgttccgcat cgataaaggc agcaatccca ccttcttttt
     7561 gcgcttgtgc aactgcatga agggcaaccg ttgtcttacc agatgactct gggccataga
     7621 tttcgatgat acgtccctta ggataaccac ctgagccaag ggcaatgtca agagctaaag
     7681 aacctgagct catcacttgc accttttgct ccgcacgttc acccaaacgc atgattgatc
     7741 ctttaccaaa gtctttctca atcaatttaa gagcgtcatt caaggccttt tcacgttctg
     7801 ccccaaattt ttttgaaatt tcttctaatt tttttggttt tttcgccatt ctattctcct
     7861 acattctaat gatcctcaga cctatctact attatatcaa aagttagtca cttaataaag
     7921 ccttgcgaac taggttaaag gcatgcataa ccgcaatgtg acgtacatct gctcggcttc
     7981 tgcctccaat attaaccttg ataacctcag ttccttgatc ttgcgccaag cctatgaaga
     8041 ctgtcccaac tgggtgtcct tctaggctat ctggtcctgc cactccagtc aaactaattc
     8101 caaaatcaga ctgggtcttg cttcgtgcct gctcagccat cttctgagct gtaaattcag
     8161 acaccacacc atgttcttcc aaattcttgg caggaatatc caacatcctt gatttttcct
     8221 ccaagctata ggtcacaaaa ccacccttaa atatacttga aactccagaa aaattcgcca
     8281 cggtagcttg gaaaagacct gccgtcaaac tctctgcagc cgcgatggtt ttcccttgcc
     8341 ttttcagttc ttctaccaca atgctggcta aactagtttc ttccccataa ccatagcaaa
     8401 agtctcgtaa agaaattcct tcgaaagtct ggcagtccaa gatttgattt tccaagatat
     8461 ccagcgcttg attcgcctct tcttgactgc tagcctttgt tgacagacgt agagtgactt
     8521 ctcctgtctt ggcataaggg gccaaggtag gatcgatctg attatcaatt aaatcagcca
     8581 aaatcgtaac caactggctc tcgccaatcc caaagaaacg aagaactcgg gaatacagct
     8641 tgctccctgt catcaacttg ggtagaagtt ggtttaagac catgggtttc aattcacttg
     8701 gcggacctgg aaggacgaca taggtcactc cgtctacttc taattttcct ccaacagcca
     8761 gtcctgtttc gtttggcagt ggaatcgctc cttctacaat ttgagcttgt ctttcgttat
     8821 tcggtgttcg ggcatagtct ggtcgcaggg caaaaaagat atccaacttc tcctgagcct
     8881 gaggatcaaa gactaatgct ttccctaaaa atttagctag ggtttgtttg gttaggtcgt
     8941 cctcagttgg ccccaaaccg ccagtcaaaa tcaccagact gctacgttga ctggcaatct
     9001 caagcaaaga caagagacga acttcattgt ctcctacagc cgtctgaaaa tatacatcta
     9061 ccccaatctc agctagtttt tccgacaaaa actgggcatt ggtgttgaca atctgtcctg
     9121 tcaaaatctc tgttccaaca gcaatgattt ctgctttcat gtttcctcct acctatctat
     9181 tcgtattttt ttgaaaaaat cgcaggaatt ttcctacgat tgattttttt atttgtatca
     9241 aaagttaatt atcttcatca ccaacaggtg ctctgccaaa taaatcttca aataaaaccg
     9301 cattggtttc aagctgagta acttcttctt gtcccaaaga acgtcggagt atattttgca
     9361 tttccaacat atgtgctctc gaaacaatct ggtaagaaac accttgaagt atctctcctt
     9421 caccctgcaa ctgctgagtt tcaatggttt taaatgaatc tttatagcct agcaagttag
     9481 ggatactttt tgcagacaaa tcaatattgg tctgcatatt gtcactcaaa gcttttagaa
     9541 tctcttgata atgaccaacg ctatttaaac tgagagcttt ttccatgact ttttgaataa
     9601 cttcacgttg acgtttttga cgaccataat ccccctcagg atcttggtaa cgcattcgtg
     9661 catagactag ggcttcttct cccccaatat gttgctcccc aacaccgata gaaatagtat
     9721 taaattcttc ttggtcactg atagaaattg ggaaacctag gatattattg actgtaatac
     9781 ctcctactgc atccactagt ttttgcaacc ctctcatatt gaccatcaca tagcgatcaa
     9841 tatggatatt catcattttt tgaatggttt ctatagcaag ctctgctcca ccatctgcat
     9901 atgctgagtt cagtttcgct tcatgagcct gaccattccc tgattcaatg cgcgtcagaa
     9961 tatcccgctc taaactcatc attgttgttt ttttcgtttt aggattcact gtcatcaaga
    10021 tcatgctatc acttctaccg acccaagttt cagttcgttc agcatttccg gtgtccactc
    10081 ccattaacag aatggttaga ggttcagtcg cttcaataac cttggtttct tcgccgattt
    10141 ttttataggt tttagctaag gtttctgtcc cttgttgata aatagtataa gcaaaaacac
    10201 ctactcctac tacagttaca gaaagtaaag ctagcaccat tccaataatt tttttaacca
    10261 tatttctact aacctatcag tttacccatc aagtaaacat cgataaattt cccttcttct
    10321 atatatgccc cacgctcttg gctaccttca atgacaaagc catgcttttg ataaagatgg
    10381 actgctgctt gattacgagt ttggacagtc agttggagac gacgcagaat gccacttgct
    10441 tgtgcccact ctatcgcttc ttctagcaac aaacttccca agccattatt ccaatatctt
    10501 tttccaatca caatgaagag atctccaata tgacggactc tcttacgctg atcagctgta
    10561 atatttacaa taccagcaat tttgccattt aagaatgcaa gtaaggttat ctgattgtcc
    10621 gaactagctt gcttgttgag gaatatttcc atctcctcac tagtcaagag aataccatct
    10681 ccgtctaggc tggtaaagtc tgtctccaaa ctcacacgat ttaaaaaggc cactaattca
    10741 gctgcatctt tgggctctgc ttccctaatg agcaattcat actccatatt gaagctcctc
    10801 taacaatttc tcagcacgca aaccctttgc ctgaaaattt aaacggcgtc catctgcttc
    10861 ttttagaatt tccaattcta aataagcatc tggcaaggca tctcctaaga gatttcccca
    10921 ctcaataaca gtcacgccgc caccaaagat aaactcatcc aagtcgatag aatcagcatc
    10981 tccttcaata cgataaacat ctaggtgata aagtggaagt cgaccctcat actctctcac
    11041 gatagtatag gtgggacttt taatcatttg agaaatctgt aatccttttg caagtccttt
    11101 agtaaaggtc gttttacctg cacccagttc tccagttaag attaaaacat cattctttgc
    11161 taatagatgg cccaaacgct cccctaaggc ttgcaactct tcttcatttt ttgtgtacat
    11221 actcttatta taccaaaaac ttttcttttg tgtctatttt cctactaaac ttatcatcat
    11281 aacatccata aaaaacaggc tttctctaaa agaaaatgag cgtaacaatg accaatacaa
    11341 gatctcggaa aatatgacca taaaaggaaa cttccttctt aaccgaattt gggacaagat
    11401 aggctgcaaa aaacaagccc agtccaatat aaatcagaag tgagacaatg gtcattggat
    11461 ttcttaagaa aagaagtgtt gctaaaatag tcaccaacac tgtctttttt ctgtccagca
    11521 tagcaagaaa atcgcgcacg tattttttca agggtaaaaa aatcagcaaa tctagcccaa
    11581 ataggaaaaa gaaggatggc aataaaaagt caactaattc ttgctgcagc gtatttttga
    11641 tgaacaagtt atctgacaaa acaagaacag ctcctaacaa attaattaag agtaacatac
    11701 tgtaaaaaag cttcaccgac ttcttactgg ctaggacact atggacttct tgcttacgag
    11761 tataaagata atttactcca gcacagattc ctgaaacgaa aaccatgctt ccgatgaaaa
    11821 aagctgtact ttgtttaaag gacaagatgc attccttcca taggaaacag ctactcaaac
    11881 tgatttgaat taaagctaac aaaaataaga ttctcattga tttcatcttc tctctccctt
    11941 cctaccaatc attatactag gagaaaagag agaactgttt ctaatcttct caaatgtctc
    12001 tttaagacgc taaacaaaca ctagagacta atactcaatg aaaatcaaag agcaaactag
    12061 gtagctagcc acaggttgct caaaacactg ttttgagatt gcagatagag ctgacgtggt
    12121 ttgaagagat ttacgaagaa tataaatttg aaatcatgaa aatccgtcaa acgggtggtt
    12181 gttttgtctc gcacctcacg gagcgagacg gactcagagt cacataatta taaggctgat
    12241 agtattaatc taactatcag ccttacaggt tatttaacgt ttcagaaaaa ctataatgtc
    12301 aagattaact aaacagtatc tagttccttc aaataatttt ctatcttcat caacattaaa
    12361 ggattgttat aaatcttaca taactctctt gcttctatat aataattttt gacttgttct
    12421 ctgtctagaa atttggctcc agcatttcct acaagaataa gtagaggagc caattggtag
    12481 cttgtctgtc tttgtttaca gagttcaatc gtttcaagag cttcttggat ggcttcatta
    12541 tatttttcct ttgatactag gtagtgagcg tagttgtaac gaactctgat gtagccaaat
    12601 aaaaactctt gatggtccaa attttttgtc tgatacaact ctattaaatg agagtagttt
    12661 gcctcatatt cttgttcacg acccactaag gaatagaaat tagatagagt attcaacgcc
    12721 tttaaataaa tcagagtatt tgaagagact tttaataata tattttccaa tgaagaaatt
    12781 gcctcacact tactgtcata ttgatagaag tcaataatag ctttaatcca ttcaaggtaa
    12841 gttcggtctt ctagtgttag aaaagtactt cgttcaatct ctattctata aatatattcc
    12901 aaatcgtcat aatttctatc gtctaatagt cgagcagaca attgcttgaa attagagagg
    12961 ttagatttaa tttcaatttg ttcattaaaa aaataatcta atggtacttc aagtcgttga
    13021 gagagtttga acaaaaggtc tgcggaggga atgaaatgcc ctctctcaat tttactaatc
    13081 tgactttgtt cacaaattcc ttctgcaaga gtttgttggg agagtctcaa ctcttttctt
    13141 ttcaatctga atttctctgc gagtgtattc attaaagata ataaaccttc ctatttgctt
    13201 aattgcatta taaaattttt agttcaaaat agcaagttaa aggaataaat aattctttat
    13261 ggtaataaac taaaaaaagt caaaaattac ataaaaatgc ttggctaaat aaaatatatc
    13321 tgttaaaata aggataatga aaaagaaaag ggtttcacga atgaagaaaa atcgtggaat
    13381 tcaaaaatta gctatattag tattactagg tgtttttatg tttagtaata caattcctta
    13441 ccaacagttt attcagaaga atagacaatt ggagattcga gtgcaatcgc aaaagaagtc
    13501 caatggtctt gatgttggga aggctgattg atttcgtatt actttaaaat tcaactattt
    13561 agagaaaggt attctgatga gagcttgtaa caataccaga tagatataag aatggagatg
    13621 tttgataaaa tgctttcata gctaaccaac tgttgaaaat tatgagttac aaaatctaaa
    13681 gtatttaaga ttggtttata aaattaggtc tctgcctgta gaaaggaacg tgcagttaga
    13741 aaggaggaaa aaataggata ctataattca gactgagatt tctaattaaa atatatagtt
    13801 gcatttcgct cattttcata atatttcatt cagaggagta ataatatgtt aaaatttaga
    13861 aaagtagttg catcatccct tgccgttttg gcatttagtt tggctcttcc tgttttggca
    13921 gtttctcacc gtggtggcga gtggacctat ggaggccatc atgatccaaa taattgggga
    13981 gcattttcga attattatca tggttcacag tatcactggg cctatgttgg aagtaatgga
    14041 cgtaacaatc aaaaaacagt ttatgcagga gcacgtagtg cggcctatgc gtttgttaat
    14101 acaaattttg gggagcaagt tacatttgat gcgggatggt aaagaataat tgaagaagat
    14161 tcttttatca atagttcagt aagcttgtta gtttatagag ggcaggagta tttctgccct
    14221 ctgttttaga ataaggaatg cactatgaaa aaattattta tactcatatc caacctgctt
    14281 gctagtttgt tctttgtttg ggtatttacc atttggactg atacatatgt ctcccattat
    14341 taccccaacg ttgttgtacg tgattcttcc cctgaaacaa cttttcagca tgttgctaca
    14401 cgcttggaaa aactagcaga agaaacagat agctttattg cgattcaaca ccaagatcct
    14461 aactcagaag gtactacagt tttttcttat acgacctttg gggacggaaa gttgcctgat
    14521 gggcttcagg aaaaaaatct agaagatgct caaagtagta gtgttgaaac aaactatttt
    14581 gtattcgatg gacacctaga tattcacttg ctaagggaag agctaagtca acttggcttg
    14641 actaacatgc acctgacaat tccatctaaa ctatctacgt taatggctat ctttagtaac
    14701 ggatttcagt taatcagtct attgattttc atcttaacct ttgtagcact gactttaatt
    14761 agtcaaatta gccaattacg gtcatcgggc attcgcctca tttcaggaga gaaacggtgg
    14821 tccattttcc ttagaccagt tggtgaggat ttgaaaggga tagctgttgg tttcagttta
    14881 gctggcgtgc tcgccattct tatgcaaaaa attctgtcgc ttccaacgca atccctaatg
    14941 accataggag caggcttgct cagttataat ctcatcttgt tgtcgatctc cctgtttttc
    15001 gctcaactct tcgcagttgg gataaaaaag atacacctga tgcagattat aaaagggcaa
    15061 gtgcctgtca gaggaatcat tagtttgatt ttaatcggtc aactgttagc gattattatt
    15121 gtaacgctgg gaatagggag tagcttaaag tattcccaag cctggcaaca gcatcggatt
    15181 ggacaagagg tttggagtca ggaaagacaa ctgattaccc tatcaatcag ccgtgaagga
    15241 acgagtcctg gttttgatga acaagctcaa aggaaactca gaacttggta tcaattgatg
    15301 gatctggctg tttcagaaca aaaggctttc ttatctagac accagttaat tgaccgtact
    15361 ttgcaaaatg gcatggcttc ctccaaaaac ttgacaacct ctacagaatg gcacgattac
    15421 agcccgaatg gcaatgtcct tatcgtcaca ccgcattact tggagcgtca aaacattcct
    15481 gtagatacaa ctattaagca aaagatgaat caccttaatg taggggagtt tgtcttattg
    15541 ctgcctgaac acctccgttc agaggaagaa cattataaat ctgtttttga agacgactta
    15601 accagtcgca tgtctagtca agatgaacga cagcaaatga ctgctacggt aggttattta
    15661 gaatcaggtc aggatcgttt tgtgtataat acgaccccta tttcttacca gcagtttttg
    15721 aaagatccaa tcatcattgt tataacaccc caatcaactg gtccacagtc cattttgttt
    15781 tggatagacg cagtacagaa ctacgttctc tttaatcaat tgtctgatgc ccaggagctt
    15841 atccagagac aaggcattga aaattgggtc tcagaaatgc aaacaggtta ccacaactac
    15901 atcacattat tggataatat ccagagggaa cgttgggtaa tgctagcagg agctgtgctt
    15961 gggattgcaa cttcaatctt gttgtttaac actatgaata ggctctactt tgaagaattt
    16021 agacgtgcca tttttatcaa acgcattgca ggtctcaggt tcttagaaat ccatcgcact
    16081 tatctctttg ctcaactggg tgtgttttta ctgggatttg ttgcgagtgt atttcttcag
    16141 gtagagatag gagttgcttt cttagtcttg ttactcttta ctggtctatc tcttttacag
    16201 ttacatgtcc aaatgcagaa agaaaacaag atgtccattc ttgttttgaa gggaggttaa
    16261 tatgattgaa cttaaacagg tgagtaaatc ttttggagaa cgagagttat tttcgaatct
    16321 ttcaatgaca tttgaggctg gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa
    16381 aacaaccttg atgaacatga ttgggaaatt agaaccttat gatgggacga ttttttaccg
    16441 aggtaaagac ttggccaatt ataaatcgag tgattttttc cgtcacgaat tgggctacct
    16501 cttccagaac tttggcttaa ttgaaaacca aagtattgaa gaaaacctta agctaggtct
    16561 cattggtcaa aagttgagtc ggtcggaaca gcggttgagg cagaagcagg ctttagaaca
    16621 ggtcggcctg gcttatcttg acctagataa gcgcatcttt gagttatcgg gcggagaatc
    16681 gcaacgagtt gccttggcaa aaattatctt aaagaatcca ccctttattc tggcagatga
    16741 gccaacagct tcaatagacc cagcaacctc tcagttgatt atggagattt tgctatctct
    16801 tcgagatgat aataggctaa tcattatcgc aacacataat ccggcaattt gggagatggc
    16861 tgatgaagtg ttcacgatgg atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg
    16921 agttactgaa atattatcat gaatcaataa ttggagttaa tttagaattg tactttatta
    16981 atattgaggt aactttttct tgataaagga ggaaatagtg gagaggaagt tagaatgaaa
    17041 aaattcgaca attatattat tgagaagcct tgcgattcta attcagataa actgcaaaaa
    17101 atcttaataa ttgaaaattt ggtagatgat attttgcaat ttcctctcag aatcaataat
    17161 agtgtaggag agattttcct cctacaaccg tttcaaaaga aaactatctt tattccatgt
    17221 tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg gaatttgtta
    17281 gaatttcaaa aatttagagc atttttggct tagtaatctg tgttgaaggc tcaaaaccta
    17341 tggtaaaaaa gtcgctttga aaacgtattg cctccaaaga tttagttaaa taatgattta
    17401 acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga gaaaaggtgg
    17461 gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata gtcaattgaa
    17521 acaagaacag gacaaaagaa ccttttgtgc catatttttc tcctttcgct ttacaattgg
    17581 cttgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc gacgcgcacc
    17641 cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta atagtcactt
    17701 aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc atgtcttaaa
    17761 ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag ccaatccact
    17821 cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa ccatgtacaa
    17881 cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga atagtgcctg
    17941 gtaaagattc ttctggacga gttgcaccca tcatggtccg ccaagtttcg attactttgg
    18001 gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga atcggtaggt
    18061 aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct gaaacctgtg
    18121 aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt aacacttcac
    18181 ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt tccatacccg
    18241 tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat ggagaaagtt
    18301 ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctcttatt ctactgtttc
    18361 ttccacagtt tcaacggcag tatccacaac tacttctgtt gtttcttcat ttccttcttc
    18421 ctctactgga ggattaaggt attcttcttc gttgacagca tgtggttcaa ggttacggta
    18481 acgggccata ccagtaccag ctgggatgat cttaccgatg ataacatttt ctttaagtcc
    18541 aaggagatgg tctttcttac cacggatagc tgcgtcagta aggacacgag ttgtttcttg
    18601 gaaggaagct gctgacaaga aactgtttgt ttcaagtgag gctttggtaa ttcccataag
    18661 gactgggcga cctgtcgctg gaactccacc tgcgataagg acatctttgt tggcatctgt
    18721 aaagtcattg atatccatga gggtacccat gagaagatct gtatcacctg gatccatgac
    18781 acggacttta cggatcattt gacgaaccat tacctcgatg tgtttgtcac cgatttctac
    18841 cccttggcta cggtaaactt tttgtacttc accgagaagg tacgtttcaa ctgacaagac
    18901 atcacgaact gcaaggagac gttttggttg gatagaacct tctgtcagag cagcaccacg
    18961 cgctacttgg cccccaactt cgacacgcat acgagctgta aatggaacga catattcacc
    19021 ttcgccagtt tcacccttaa caaagacttt cttggtacga gttgatgcat cttcttcgat
    19081 agcagtaact tgtcctttaa cctctgtgat aaccgcttcc cctttaggat tacgggcttc
    19141 aaagatttct tggacacgag gaagaccctg agtgatatcg gtatttgagg caaccccacc
    19201 tgtgtggaag gtacgcattg taagctgtgt accaggttcc ccgatagatt gggcagcaat
    19261 tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc gccaagttga taccgtaaca
    19321 gtgacggcag acaccgtgac gagtgttaca tgtaaataca gaacggatag tcacttcttc
    19381 cacaccagca ttgacaattt cacgcgcctt gtcttctgta atcaattcat ttggaccaat
    19441 aatcactgca ccagtttctg gatgtttaac agttttctta gtgtaacgac cgttgagacg
    19501 ctcttcgaga gactcgatca tctcttttcc ttctgcgata gaacggatca agagaccacg
    19561 gtcagttcca cagtcgtcct cacggatgat aacgtcttgg gcaacgtcga ccaaacgacg
    19621 agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg gtcatacctt tacgagcacc
    19681 gtgagttgag aagaacattt ccaataccga caaaccttcg cggaagtttg aaaggattgg
    19741 caattccatg atacgtccat tcggagcagc catcagacca cgcataccgg caagctgtga
    19801 gaagtttgag atgttaccac gggctccaga gtccatcatc ataacgattg ggttcttagg
    19861 atcttgatta gcaatcaagc gtttctcaag tttttcacgg gcagcacgcc attcagctgt
    19921 aacagcattg taacgctcgt cgtctgtgat cataccacga cggaattgtt tggtgatttg
    19981 ttcgacacgt ttgtgtgatt cttcaatgat ttcagccttg tcatcaacga ctgggatatc
    20041 ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg taaccgaggt tcttcatgcg
    20101 gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg aagatttcag cgatgatatt
    20161 tccgaggttt ttcttcttga atggagggtt gagctcaaga ttgctgatag cttccttgat
    20221 atctccacca agtggcaaga agtatttagc tggaacacct tctgtcaagt tggcattgtt
    20281 tggttcttgc aagtatggta gcccctctgg catgatatcg ttgaagagaa ttttaccaac
    20341 tgttgtaagc aagaccttat gtctttgctc ttctgtccaa ggcttgttga ggctgtctgt
    20401 tgcgatacca acacgtgagt ggaggtgaac ataaccattg cggtaagaca taaccgcttc
    20461 gtcacggtct ttgaagacca ttccttcacc ttcgcgacca gcttcttcca tggtcaagta
    20521 gtagttaccc aaaaccatgt cctgagatgg agtaactacc ggtttcccat ctttcgggtt
    20581 caagatgtgc tcagcagcta gcatgaggat acgagcttct gcttgtgctt cttctgaaag
    20641 tggtacgtgg atggccattt ggtccccgtc aaagtcagca ttgtaggctt cacagacaag
    20701 tgggtgcaag cgaagagcct taccatcaat taagactggc tcgaaggctt ggatacccaa
    20761 acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt tctttaatca cttcttcaag
    20821 gatatcccag atacgctcat ctccgcgttc caccaagcgt ttagctgctt tgacgttttg
    20881 cacgatatca cgggcaacga tttcacgcat gacaaatggt ttaaagagtt caatcgccat
    20941 ttcacgtggc acaccacatt ggtacatctt aagagttgga ccaacggcga taactgaacg
    21001 tcctgagaag tcaacacgtt taccgagcaa gttttgacgg aagcgtcctt gtttaccttt
    21061 aagcatgtgg ctcaatgatt tcaatggacg gctacctggt cctgtgattg gacgaccacg
    21121 acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc atacgcttct cattttgaac
    21181 gatgatacct ggtgcattta actcaagcaa acgagccaaa cggttgttac ggttgataac
    21241 acggcggtaa aggtcattca agtcagatga ggcaaaacgg ccaccatcca actgcaacat
    21301 tggacgaaga tctggtggga taaccggaag gatgttaaga atcatccatt caggtttgtt
    21361 tccagacttg taaaaggcat ccaaaacatc caaacgacgg atggctttga cacgtttttg
    21421 tccagtagct gttttcaatt cttctttgag ttcagcaatt tctttttcaa gatctacttg
    21481 cttcaaaagg tcttggatgg cttccgcacc catcttggca acaaatgaac cataaccata
    21541 ttcacgcaag cgctctcggt attcgcgctc tgtcatgata gacttgtgct caagtggtgt
    21601 atccttagga tcaatcacca cataagccgc aaagtagata acttcctcga gggcacgagg
    21661 gctcatatca agggtcaagc ccatacggct tggaatcccc ttgaagtacc agatgtgaga
    21721 tacaggagct ttcaattcga tatgtcccat acgctcacga cgaactttcg tacgcgttac
    21781 ttcaacccca cagcggtcac aaacaattcc tctgtaacga atgcgtttgt acttaccaca
    21841 agcacattcc cagtcttttg taggaccaaa gatcacttca tcaaagagtc cttcacgttc
    21901 tggtttcaag gtacgataat tgattgtttc aggttttttg acttctccat aagaccatga
    21961 acggacttta cttggagaag ctagggtgat ttgcatactt ttaaaacgat ttacatcaac
    22021 cactatttct tccctttcta ttctaagtga actgcttatt cttgttcagc agcttcttct
    22081 gttgcttccg cttttgttgc tttctcagct tcttcagctt caaaggctgc tttagcctct
    22141 tgggctgctt tttcgcgggc tttttcaagg tcatctacgt ggatgacatc ttcgtccatt
    22201 ccttcatcca agtcgcgaag ttccacttct tggtcatctt cgtctaggac acgcatgtca
    22261 agaccaagag attgcaattc tttgacaaga actcggaagg attctggaac acctggtttt
    22321 ggaattggtt tgccttttgt aatagcttca taggctttca aacgtccgtt gatatcgtcc
    22381 gacttgtaag tcaagatttc ttgaaggaca tttgacgcac cgtaggcttc aagagcccaa
    22441 acctccatct caccgaaacg ttgtccacca aactgagctt tacctccgag tggttgttgg
    22501 gtaacagttg agtaaggtcc gactgaacgc gcatgcaatt tatcgtcaac catgtggtgg
    22561 agtttgatca tgtacatgac tccaacagaa acacggttat caaatggttc acctgtacgt
    22621 ccatcgtaaa ggattgtctt ggcatcgcta tccatacctg cttctttaac agttgaccaa
    22681 agatcttcag aacttgctcc atcaaagact ggtgtcgcaa tgtgaatacc aagagtacga
    22741 gctgccatac caaggtgaag ctccataacc tgaccgatat tcatacgtga tggcacccca
    22801 agtgggttca acatgatgtc gactggagtt ccgtctggaa ggtaaggcat gtcttctaca
    22861 ggaacgatac gagagacaac ccctttgttt ccgtgacgtc cggccatttt atctccgacc
    22921 ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca tgttaacacc tgattgcaac
    22981 tcatctccat ttacacgtgt aaagatctta acatcacgaa cgacaccatc ggcaccgtgt
    23041 ggtacacgaa gagaagtatc acgcacttca cgagacttgt ctccaaagat agcgtgcaag
    23101 agacgttctt cagctgaaag atctttctca cccttaggtg ttactttacc tacaagaata
    23161 tcaccttctt taacctcagc accaatacgg ataatcccca tttcgtcaag gtctttgagg
    23221 gcatcttcac caacgtttgg aatttcgcga gtgatttctt caggcccaag ctttgtatcg
    23281 cgcgtttctg attcgtattc ttcaaggtga acagatgtgt agacatcgtc cttcaccaag
    23341 cgttcgctca tgataacggc atcctcgaag ttgtaacctt cccaagtcat gtaggcaacg
    23401 attgggtttt gtccaagcgc catttctcca ttttccatag aaggtccgtc agcgatgaaa
    23461 tcgccttttt caacgacatc accaactttt acgagagtgc gttggttgta agcagtacct
    23521 gagtttgaac gacggaattt ttggatgtgg taaacatcca atgaaccatc ttcacgacga
    23581 acttctacct tatcagcatc tgcgtaagta actttaccat catactgagc aatcacagcc
    23641 gcaccagaat cgtgggctgc ttggtattcc ataccagtac caacgtaagg tgcctgagga
    23701 ttaatcaatg gcacagcctg acgttgcata ttggctccca tgagggcacg gttggagtca
    23761 tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacctgttt tggtgaaacg
    23821 tccatgtagt caacaatatt agctggatac tcttggttga ccccttggtg acgtcccatg
    23881 acaatcttct cagcaaaggt tccatcttca ttcagacgag agttagcctg agctacagta
    23941 tattcatctt cttcatcagc tgtcaaccaa acaatttcgt tcgtgacaac acctgtttca
    24001 cggtcaacct tacggtatgg tgtttgaaca aaaccatatt tgttcaagtg tccgtaagat
    24061 gacaagttat tgatcaaacc gatgttaggt ccttcaggtg tctcgattgg acacatacga
    24121 ccatagtgag tgtagtgcac gtcacgcact tcatatccgg cacggtcacg agtcaaacca
    24181 ccaggtccta aggctgacaa acggcgtttg tgagacaact cagaaagcgg gttgtgttgg
    24241 tccatgaact gtgacaactg tgatgaacca aagaattctt taactgcagc tgttacagga
    24301 cgaatattga taatttgttg tggtgtcaag acttcattgt cctgaacaga catacgttca
    24361 cggacattac gttccatacg agaaagtccc aaacgtactt ggttggcaag caattcacca
    24421 accgcacgga tacgacgatt tccaaggtgg tcgatatcat ctacacggcc aagtccttca
    24481 gccaagttga ggaagtagct catctcagca aggatatctg caggagtcac cgtacgaacc
    24541 ttgtcatctg ggttagcatt accaatgatc gttacgacgc gatctggatc agttggagca
    24601 acaaccttga atttttgaag aacaacaggc tcagtcacaa cggctgcatc gtttgggatg
    24661 tagacaatct tgttcaagtc gccatccaaa tggctttcaa tgctttcaat cacgctacga
    24721 gtcataatcg taccagcttc taccaagatt tctccagttt cagggtctac caatggctct
    24781 gcaatggttt ggttgagcaa acgtgtttta acattgagtt ttttattgat tttgtaacga
    24841 ccaactgctg ccaagtcata gcgacgtggg tcaaagaagc gagccacaag caagctacgt
    24901 gagctttcag ccgtcttagg ctcacctgga cgaaggcgtt cgtaaatttc tttcaaggct
    24961 tcgtctgtac gagagtccat tggattcttg tggatatctt tttcaacagt gttgcgaacc
    25021 aattcgctgt caccaaaaat atcaaagatt tcatcatcac ctgagaaacc aagagcacga
    25081 accaaggttg taaatggaat cttacgagta cggtcgatac gagtgtaggt gatatctttt
    25141 gagtcgcttt caagttccaa ccaagctcca cggttaggga taacagttga accatagccc
    25201 accttaccat ttttgtctac tttgtcgtta aagtaaacac ctggtgagcg gaccaactga
    25261 gaaacgataa tacgttcacc accattgatg atgaaagtac ccatttctgt catgattggg
    25321 aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg tttctttatt gatcaagcgg
    25381 aaggttacaa aaattggtgc tgagtagcta gcatcgtgaa tacgagcttc ttctagcgtg
    25441 tattttggtt ccttgatttc atatccaaca aattccaact ccattgtgtc tatgaagttt
    25501 gaaattggca atacatcttc aaacacttcc ttaagaccgt ggtctaggaa agctttgaat
    25561 gagtcagttt gaatttcaat caaatttggt aagtcaagaa cttctttgat tcttgaaaaa
    25621 ctacgacggg tacgatgttt cccgtattga acgtcatgtc ctgccaagat gattctcctt
    25681 tgtaaataag ttccaagcct tgtcaatcag gcttttctaa tcgtcatatg gttgtaaacc
    25741 ccttatcacc gtgtcctctt gacgattttt cagaatcttt aagcctctgt tacaaatgct
    25801 caaaatcttg aaaaaaagca caaaaagagc agctaaatct gactttttca gaagatttaa
    25861 ctgctgtgag ccttgtctgg acaatatttc agacaaaacc tacgacaaat gattacccat
    25921 attataccct atttagctag atttttcaag gggtttcagt aggtttttgg taaatttttt
    25981 cccatagaaa acttggcatc acattcgaat cacgctatgg tacaaaaaac tgaaaaaact
    26041 attgactgaa aatcattttc aaggtataat aataaacgtt aaggcggtat agccaagtgg
    26101 taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat ccgtctaccg ccttctataa
    26161 cttgatttat caggtttcaa atgaacagaa agcccaattt gaagggcttt tcttattttc
    26221 cctcgaataa atacgtataa ctttaaaaac ttttggagcg agtttgtggc agagttcttt
    26281 ccatggcata attccctttt gaaatcaatt gaaaaaagct tcgtcacgcc tggtgacaaa
    26341 agcctctagt ttattctgtt tcttcttcta tttcgacttc tgtgatttgg atttttacct
    26401 tggtaacacg tccattcttc actttatcat tggttaagat aaactgtttg ttttggctga
    26461 ccaattcata gctgagtttc tcagtcgttg gaatggttcc cactcctgtc aaataataac
    26521 cagcgatagt atcaacgtca tcactttcca gttcaacatt aaagtaatta ttgaaatcat
    26581 tgagggtcat agttccttga acaatgtagg tatcctcgcc aatctgatga acatctattg
    26641 ctgctttgtc cgtttcatca tcaatttcac caacaatttc ctctaagagg tcttccaaag
    26701 tcaccaaacc agccatacca ccgtattcat ccagcaagat tgccatttgt ctttgggtat
    26761 ttcgcagttc ttttagcaag tcatccacaa aaatagtttc aggtacaaaa agtggatctt
    26821 gtaaaattct cttccaaaca atattgtcaa aaccgtccac aaagcctgcc ttaaggagac
    26881 tcttggtgtg aatgattcca attacattgt ccttatcccc atcataaacc gggatacgag
    26941 aataattttg ttttaaaata ctttggataa tggcttgact atcatcctga atatccacca
    27001 taaaggcatc cgttcgagga accataacct ctcgtgccat cagttcatcg agcgaaaaga
    27061 caccttgtag catctcaatc tcatcagcat ccaatgtttc ttcactattt gtcagcatat
    27121 aggcaatttc atcacgggtc atcttttcat ccgcatcatc gaatgacata ggagtcaaat
    27181 ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa aggactgact agttttccga
    27241 tcccaatgat aaccggcgct gtacgaattg ccaaggcatc ctttagatta agagcgattc
    27301 tcttaggata taattcccca aaaacgatgg aaatataggt caaaaatgcc aaggatagaa
    27361 aagttgccac ggcttgtgct gtttcgccat tcccaagcca agaggcaatc acacgtccta
    27421 gagtattagt taaactcgcc cctgataaga ttgtaatcag ggtgattcct acctgaatgg
    27481 ttgataaaaa gtggttagga ttttctagta ccttcagcag gcggatgtag cgtctgtctc
    27541 cttcttccgc cttttgttca actcgggcac gattaagaga aaccatggcc atttctgtgg
    27601 ctgagaaaaa ggcatttaat accgtcaaga taaacaataa aacaaattgt agcaacaaat
    27661 tctgactact tgggtcttcc atagttcttc tcctaaaata gtatcttatc ctttattata
    27721 tcacaaaatt taatccaata catattattt ttttcttagc gtaacttcca tctctctccc
    27781 aaaactggaa gttagtctaa gacggatttc cactgatttc acgcgttttt ctcatactaa
    27841 aagctaggtt gtgggaaact ggaagttagt tttagaagtt actatttttt cttagtacct
    27901 gttctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga cataggagtt
    27961 taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca gttgaagtcc
    28021 cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag acttggcttc
    28081 aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg ttacacggta
    28141 acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt agttttgacc
    28201 agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa tgtttttagg
    28261 attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc ctaacaaatg
    28321 acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat gccaacctgg
    28381 aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact gacgagtggc
    28441 cttagacaag agagcattag ctacggttgg aacagtttcc ttgcccactg tctttgtttt
    28501 attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat taccattgac
    28561 gataaaagca cctgagccat tccactccag actccccttt atttgactct tgactgcgtc
    28621 tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt ttttctgact
    28681 catttttgtc ttagcagcct gatttcctag ttcattctgc ttaatataat agctccctgc
    28741 agacaaaagc aataacacta gcagtccaat cagtgtctgt cttgtttttt tgttcatatt
    28801 tctccttatc tttataaaaa ggctggtctc ccagcctaat ttcctgtaaa tttatgaatc
    28861 aattcctgcc attttgccgg agacaggata gcccacggat cttgaccctt gcccaagatt
    28921 ccatagccta ccattaaacc gattcctaag gctagaaggc ctaaaatcag taccagaatg
    28981 actaaaagta aacgcttaat tacgtaacct gatttcttat tcatcttcat cacttgcctc
    29041 aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt agtaacctct
    29101 atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac ctgtcaaaat
    29161 caaggccgca ctggcacgaa ggtcagttga aagaacttct gctccctgca aaggctgtcc
    29221 accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc ggcgcatctc
    29281 ttctaggtgt tggaaacgat tttcaaaaac tgtctccacc atggttgatt cgccttttgc
    29341 aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg ggtggggcaa
    29401 ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa ttccttcgtc
    29461 ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac ggttgtgctc
    29521 ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta ccataaaggt
    29581 tcctgcttcg atacggtctt ggactacatt gtgagtcgtg ccatgaagtt tctcaacacc
    29641 agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt cattaaggag
    29701 aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg tcaccccatc
    29761 agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa agtccatata
    29821 gatatgagcg ccatgcaagc gttctgcctt ggcttcgatg taaccagctg tctgactaat
    29881 cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc taccaatcgt
    29941 acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg gccctaatac
    30001 aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag tgatgtcgcc
    30061 agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg cattcaaacc
    30121 accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct gcaagacggt
    30181 ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat tttttgctcc
    30241 ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa ttttatccat
    30301 actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg ccacaaatga
    30361 tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa aaaggctact
    30421 aataaacgaa cttttcttgt attatcatct gtcactttta aaaccttctc ccatctaaca
    30481 agatccttta aaaggtaaaa actcacataa ataaagaaca tatgactact tagagtgaat
    30541 aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag tttggaaact
    30601 tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag ggttttaacg
    30661 ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt ttggtagttg
    30721 tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc aggagcaaag
    30781 aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc tccaatgtct
    30841 cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc attacgaaga
    30901 tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc acttggaccg
    30961 ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt acggtcaatc
    31021 aagccgattc caattccatt tttgccattt tccaaggtga tgatttttcc ttctgcagac
    31081 ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt ttgagaactg
    31141 acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc tgtgaccgta
    31201 tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa aacataaact
    31261 ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata cttggccata
    31321 ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc ggaagaacca
    31381 cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc ataaatcata
    31441 tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc agcttcctta
    31501 tcttctgtgt catttacttt aaggacttgg cgaatatctt ccgaaccacc tggaacctct
    31561 atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc cgcaatgacg
    31621 tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac tctcgggaac
    31681 atagcaggca atatcctgac caaacttcaa aagctctcta acgcctgatg aactgatata
    31741 gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca gctgatgatt
    31801 gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac cacgcactag
    31861 acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag aagccacgac
    31921 ttcaacattt tccaaatgtc ccaaagcctt ttctagcccc cgtttacgat tttcaagagg
    31981 gagaaatcct tgtttgtggg gattaaaaaa aatacccaca caaagcttat caaaaagtct
    32041 gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg agcctgtgaa
    32101 taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc ttttccttcc
    32161 agatacccag acaggcaatt tcttctggaa gttcaacggc cttatccgtc tcgcacacaa
    32221 ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct gctacgattt
    32281 gttccttggc atagggaggg tctaagaaaa cgaggtcaaa ttccccagat acctgttcca
    32341 atgccctctc tgcatccatc ttgaggagtt gaaattttcc aacttccttg gtcatctgga
    32401 tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca gcactggaca
    32461 tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg tccaagactc
    32521 gtcccccttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc ttatccgaag
    32581 taggtcttgt tgtcttgcct tctagtgtct tgaggggacg tcccccatag attcctgata
    32641 cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa aaccgaacct
    32701 tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg aggccaaaca
    32761 cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat acgagattgt
    32821 ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt gtgccattcc
    32881 aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt ttcttcatct
    32941 acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt ccagacaaga
    33001 atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc atcatagtct
    33061 ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc aatcaaaaag
    33121 acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa gtctgggtag
    33181 cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat agactcgatg
    33241 tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat cttctcaact
    33301 gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc ccagtcccac
    33361 tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg aagggctttc
    33421 atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt gtggcgtttc
    33481 catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag aaccttgacc
    33541 gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac cttactcaag
    33601 ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt aaaagtgttt
    33661 ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga caactcctca
    33721 aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa aatttaaaaa
    33781 aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga ccaaagatac
    33841 gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc attgacacca
    33901 cccagcctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc ttttggttat
    33961 cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata taatcaaaga
    34021 agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg agagctgcca
    34081 tcattgctcg accaatccca ctcaagtctt tcttggtaaa gataccaact gccgccatga
    34141 caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga gtatagaaag
    34201 ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat actggaagag
    34261 cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc aactccgcaa
    34321 aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac tgagactgaa
    34381 agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga ccaacaaagg
    34441 cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata gtgtgattca
    34501 tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag ttaaaattag
    34561 cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc ggcctgcccc
    34621 ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact aattccttga
    34681 ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct gtaatcaaca
    34741 gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt ttcgtcaaga
    34801 agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg catggaacgt
    34861 agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc tgtaaaacct
    34921 gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac atcttccaaa
    34981 aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg aaccacggca
    35041 acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc tgacacccag
    35101 acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa gattttctca
    35161 atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat caaataggct
    35221 gacttgcggt attttttttg gtgtaatttc ttggtatttt ttaccacaga attggctttt
    35281 gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt atgcaaaagg
    35341 ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt gtttacagct
    35401 tggcacttga aattggtggc atcacaggtc gagtatggaa taacgacgat ggcacagtgg
    35461 aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa gaaatccgaa
    35521 aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc aactttcctc
    35581 cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat tttgtaaaaa
    35641 aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga aatctattaa
    35701 acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg gctgtgtcaa
    35761 tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg gagcgcctat
    35821 ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg tcgctatcat
    35881 tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc aatcatggaa
    35941 ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc cacaccaaac
    36001 acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag ccctctttgc
    36061 cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc ctatcctcct
    36121 tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag gggttgctca
    36181 agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg cctgtgctgg
    36241 tgtcctttac tatcttcaat cgctcctttc acttcacgga gtagaagatg aaatgcaaag
    36301 agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct tctccctctt
    36361 ctcaccagct agtgtcacac tttactgggt tgtcggtggt ttcatgatga ttctccaaca
    36421 gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg aagaactagc
    36481 caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag acgttacccc
    36541 tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg ctggaaaaca
    36601 acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg caaatcaaaa
    36661 gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat aatcttgata
    36721 actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg gtggtttgac
    36781 tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca tggtgtgata
    36841 aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac caagttcaat
    36901 caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc agacaggttt
    36961 tccaatatct gatagatact gggcacaagc caagatattt ttattagttt gtctagtgac
    37021 aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt cagtgacagc
    37081 catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa gagcacaggt
    37141 atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa tcaggaaatc
    37201 aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc cccagaaacc
    37261 acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg acttattgga
    37321 ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac agccctgcaa
    37381 aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg tcgaatgcac
    37441 cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac cttccttgaa
    37501 aacgttttat agttttatta tatcacgact tgaaggaaaa acaagatttt tgcctatttt
    37561 ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta ttcttcaaaa
    37621 tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg gatttgacgg
    37681 gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt atactggtag
    37741 cccattgaaa atccgtgggc acctgtatca tgaattacca gcaaatcacc gatttctgta
    37801 tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga accaaccaca
    37861 tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg gtaagctccg
    37921 tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata ggtacggtag
    37981 gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag cataaaacga
    38041 cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac ttcttcatac
    38101 accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc tggacgataa
    38161 ttaacaccaa taccgccaga aagattgata aagtctagcc aaatgcccaa cttttccttg
    38221 atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag atgggtcacg
    38281 gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc cttcaagata
    38341 gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc aggattgtcc
    38401 ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga gatgatttct
    38461 ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa gttaatggtc
    38521 gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga agagaacata
    38581 atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata actagagcag
    38641 tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg agtagcctta
    38701 actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac ggctcttgcc
    38761 ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc ggcaacaatc
    38821 gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct attctgtttg
    38881 caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt atcttcgtca
    38941 aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt ggttaccttc
    39001 aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc cgcaaagacc
    39061 gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc attgaccgtt
    39121 ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt aagactacgt
    39181 tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata gttgacgcta
    39241 acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga gacattgagg
    39301 acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat aaccgcgtca
    39361 attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa gatggctggt
    39421 gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc actttctgac
    39481 aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat agacggtgtg
    39541 aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc aatttcctca
    39601 aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga ctcatacttt
    39661 tcagcaaaag tattgagact agttagttta taaggattat taatcaaata gttggaaatg
    39721 acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat ttttattcaa
    39781 aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg ttttgagatt
    39841 gtcaatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac aaggcgatac
    39901 taccctagtt tgaagagatt ttcgaagagt attcattttt gtcttttact tattatacca
    39961 tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc ttaaattatc
    40021 aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta ttggtcatct
    40081 ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca tccagattgt
    40141 caatcatatg gataatctct gcctccataa tacgtggacg gactggactt ccatattcaa
    40201 gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc ttggtatcat
    40261 cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg atatgtccaa
    40321 gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg atgaccttag
    40381 ccaagtcatg cagcataatc cccgcataga gcaggctctt attgagctga ggataaactt
    40441 cgctaatagc gtctgccaaa cgcaccatgg tcgccgtatg ataggccaag cccgtttcaa
    40501 aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca tacttggtgt
    40561 agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc atttgcgaca
    40621 tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatca gctgggtcat
    40681 tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg gtattgttat
    40741 aaacttctcg gcgtcctttc atgtgggcaa ccttacctgc ggtaaaggcc tcaatgttat
    40801 gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg aaggtaaagg
    40861 ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt aggtaaaagc
    40921 cttcaaataa ctcatctttt ttcatgtgac taatcttcat attcttcctc attttcttga
    40981 aaatggagta gatcaagcgc aggctcacct tctgacaact caatgtgacg gagcgtccgc
    41041 tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc atgttggaga
    41101 tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt gacactggca
    41161 agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa accaactgat
    41221 agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg ttcttcccgt
    41281 ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc ttctgtcgga
    41341 acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt cctaatatcc
    41401 ctagcaaagc gcttgacgct tgctaggagt gacttacgac agcgttcaat ctcatccttg
    41461 tcacctgtct cataggctgc ttccaagcgg taataatctg ccagtggaaa cttagagtca
    41521 attggcagat agacgtattc ttggtcgcct tgtccgggta acttgatggc atactccact
    41581 cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg tgtcatgatg
    41641 tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt ggttccagag
    41701 agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc aaggccacga
    41761 ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg tgtctgcaag
    41821 gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg ctcatttgat
    41881 tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag attatctgtc
    41941 atttcttgac ggacttgggt cagaccttgg tgcaattcaa tccgcacttc ttgcaaacgg
    42001 tcgctgacaa ccacttccaa atctttttgg tctaactggc tggcttgtct ggcttggtca
    42061 aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct cttacttaag
    42121 tgtttctcct gcctatcctg cctttgccaa atcagaaaga gaccagctag attggcaatt
    42181 aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca gtacgaccac
    42241 ataaccatct gggcaagtta ccgacacttc cctatctata tattcgttag aagcgtacac
    42301 ttttttaaag aaaaaatttt cctctgtcaa ctcatacttg gctccaagaa tagtcagctg
    42361 gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt ctagctgact
    42421 gattccttct ggacaataag taatcaagtt ttgcccatcc tcaatttcta tttgatgcat
    42481 atagggtgcc aacttaggat tgctaggcag aaagacattg gccaacatat ggtcaatacg
    42541 gccacccaag gcaccgaaaa tagtgacctg agcctgagga ttttgttcaa agatggttaa
    42601 gagagccaat tccagatctg tatcatcctt ttctggtcgt gcttggacaa aatactgggc
    42661 acctttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatctc cgactgctag
    42721 agcaagaggt aagtcttctt ccaagaccca gagcgagcct cgatccaccc caacaaaagc
    42781 atcaaaatct gtccgataat gaccgcggtt tccgcctgca aaaactgcaa ccctagtcca
    42841 gttgttttct gagagtttgt actcgctcat tgacttctcc cttaaagaca taggaacctg
    42901 ctacaaaaac agtcgcaccg gcttctttgg cttgagcaat agtttggtca tcaatcccac
    42961 catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc aactcacgga
    43021 ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta accgtcatga
    43081 ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat gtgccaggat
    43141 tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg ccatgaatat
    43201 gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca aaatcttcca
    43261 gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta ctatgaggac
    43321 gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga ctgtccatga
    43381 tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca cgttcaaagt
    43441 tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata ggtttctcct
    43501 tattttggaa tttttttgct gactttttta taggtttctc tacgattttc aatttcacta
    43561 aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc aacagctggt
    43621 ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca atctcggcta
    43681 acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac ttcatagtcc
    43741 aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta aaaactaaca
    43801 gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt ttcaagattg
    43861 aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg ccccataaag
    43921 accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac aaagtcatag
    43981 ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc caacaaatcc
    44041 attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac caagaaacga
    44101 tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac agcttgatcg
    44161 atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt gaggatatag
    44221 ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg ggtatggcct
    44281 tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact ctccacatag
    44341 tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt gccctttaag
    44401 tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca cacttggtga
    44461 caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag tcttaccaaa
    44521 gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag ccttggaaac
    44581 cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac gcaccatttt
    44641 caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca cgataaaggc
    44701 aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag ccttggtgtt
    44761 aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa actcacaaaa
    44821 aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt aaggcaaatt
    44881 agccactacc ttgattggca ggtcaggatt tttaaaattc tggatatgtt gcgccaaatc
    44941 aaccttgaga atatcttcgt taactacggt cacattatca aaatcacgca gggtatctgc
    45001 caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg cacgctcagc
    45061 caaaaattct gtcaaggcac caatacctgg cccgatttcg atgacattga cctgatcatc
    45121 aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcaaaa aattttgccc
    45181 aaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca cgctataatc
    45241 tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac acattcccct
    45301 tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag aaagatagtc
    45361 ttggaaatct ttaaaagtgg ccttagcagt tctctcgaaa catgcgttca aaaaaatcag
    45421 cttcttgata acttcgattt tcaggtaggg tcaaatccac atcctcctcc acatcatcca
    45481 ctgtcagttc aaccatctga ggtaaatttt tcaaacgata atgcttttgc ctttgccctt
    45541 caatactagc aaaatcaagc aaatagccat gcactcggat ttgaaccaaa aggagatgat
    45601 tggtcatatt ttccatgatg aggatatctt ctaaaccacc tctggcacta ggataatcag
    45661 ataccctgcg aatacggatt ttttcacaca tgagcaagtt tcctcatatc aatgatttca
    45721 tcagccttat tccagactag gggattatgg gtcgcaatga tgataattcg attttcatct
    45781 ttcaaatcca ccaagagatt cataacctct tctgaatttt caggatcaag agctgctgtt
    45841 ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag tcttagcaag ggcaactcgt
    45901 tgggcctctc ccccagataa agtatagatt ttttgttcta aatccaaata ccctagatta
    45961 actttttcta aagcccccac ttgcctttcc aaacgttcta cttttgagat tttctgacca
    46021 acaaaaccca aatccaaatt ttctttgatt gattggtttt ctaagaggcc gaaattttga
    46081 aagagatagc ccatctggtc tcgaaaatac tcacgagtgg gaatggtttt taaatctttc
    46141 ccctgataga gaacccttcc accatctatc ttttctagct ttcccaagat attcagcagc
    46201 gtcgtctttc cgcttccact ctttccgatt aaggcataaa ccttgccctt ctccagcttg
    46261 agattcaaac cagagaaaat cgcgcggtca ttaaatttct tttccaatcc ttgaatatca
    46321 atcatcttat tttcctttca atactgccat gctaccagct tcttcttttt tgtcctgcct
    46381 tactaaaatc aagagggcgt taagcgtaaa caaagctaca actagagcgc taatcaaacc
    46441 atctcttgtc aaaatactag ataggactag gccaagcaag agaactcctc cttgcgccag
    46501 taaatacttg ccatgaagct catagattgt cataccagca agacgtttaa tcataagttc
    46561 ccgtctgaac tgctcaaaat agagaagatt catggaatca aataacaaga tagccgtaga
    46621 cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc acccgtttgt catttagtac
    46681 cttggcaaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca gacctttctc
    46741 ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat tagccgtagt
    46801 tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta gaactacaat
    46861 aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga ggaaacgttc
    46921 ctgtcctgtt tctgtaaaag ctagccttac ctgtgggagg tagtgtttct gactcgtcac
    46981 ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt ggtagtagac
    47041 agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag acaagttttg
    47101 catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat agcgtggtga
    47161 gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat ctaggtccac
    47221 ttctgctcca tctgagaaat tgtcaacatt gctcataata taaaaagagt ctgtattggc
    47281 taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc cttcttcatc
    47341 ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact ggctccattt
    47401 attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag ctgtcgcact
    47461 cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca ttatacgttt
    47521 gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac caagtagata
    47581 gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta gaagagcaat
    47641 gatgaccagt tgcaccgttg ccataaacaa ggcaccttga taccagagaa tccccaatcc
    47701 caaaagactg gataccagca ctgagcagat aagctgtctc acatcttcta acactggtct
    47761 gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct gacgaaggga
    47821 tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag ctaaactcag
    47881 tagcaccata ggggtggccg tcaatagtaa gactatcgaa aatggatctt ctccattcga
    47941 aacaaagcct tgataaccaa gctctttcaa ggtggtctgt aagctcactc catccaaact
    48001 tcctgataca atcaagtaag accctaataa atcactcgtt tctgcactct ccttggagga
    48061 aatggtcaga ccttctggaa gctttccctc accataagtg gcataggtaa agcgtgtttc
    48121 tccagcttca tttggctcaa cgattcgacg agcaatgaga ctattgtgct ctaccgccaa
    48181 gtgactcaaa gcctctgtca cctcttcgcg actagctact ggttgattta tcatcattcc
    48241 tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt caacggaagt
    48301 tatcaccata taaagcgata ctaataccat tgaaatcaaa ataaataaac gtttcatcat
    48361 ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccaagtaaag ctaaacaata
    48421 gggctatacc attctaaaca ttatagtaga atgcaacttt ctctccccaa gaagtacgaa
    48481 tccacgcacg agaagtccct ccagcaccag catatccctt gtcagatgaa ccagtttttc
    48541 tgctaacaac tgttgaacta tggtattttg aagggtgata gtagtttgag taagcaccac
    48601 cgttacctga accataagtc caaacaccac cttctgggta ttgaacggct gcagaggcaa
    48661 ctgatacacc tccacctaat gttgctgcaa tgctcgctac aagagctaac tttttaactg
    48721 tttgtttcat attgatactc ctctattttt gattacaaga ttgttgagtt acttgctcct
    48781 ctttccatta tcaacgttga tactattata ttaccaaatg atattctaaa attatttgtt
    48841 tttctctaaa ttgtcaaaat agcaccctga aatgaacttt tatagtcatt atactccatc
    48901 tttatcacac tatcaaggac atcaatgtcc ttaaaatcta actatttcat attattttta
    48961 gcttatatct aaaaaaacag ttctaaagac gaactttaga actgttttga tacgaggaca
    49021 aggacatttt tgtcactgat tcactatgtt tataaatatt ttttgacatc ctcttgccat
    49081 tcctctgtca atttctttac tagaaatcca tctccaatta gcttcgcaaa tgttttagaa
    49141 gactgataaa atgattcagc taaactaaaa tctctttcta ctcttaatgc ttgcttccac
    49201 aaaaacataa atacaagagg tttcttttga taatcttgag ttttatccat aatttcttgt
    49261 aaacacgata gataatcatt aaaacaatca gttactccta ccttttcaag acaacacatt
    49321 cctgaaataa gagtatctct aattataaag taattctcta tttgagttac cttcttctgt
    49381 tccaaaagaa agagcattag cttttcgatt tgatttataa atttggcaag atcttttcta
    49441 atgagcattt gataaaaaaa caaacgaatc aacaacatat catttattga ataagcttct
    49501 ttttctataa tctgaggcat atgttcctca agtattaact ctgcatattc aggccttcta
    49561 gttctagaag tatccaaaca cgcctgcaat acttcacatg ctaattgttc ttctttagga
    49621 agattatcaa agtatgtttt ataaatctct tccaaacacg cttccttctt atcgtactcc
    49681 tcttctttac catagattgg ttcacgtaaa atctggtatt tcaattctaa ataagcagaa
    49741 ggaagagctg aaaaatccgg cataaggcta taaactggaa ctcctagccg gcgagcaata
    49801 taggctaact tgggcaaact cggttgcgaa gctccacttt caattcgcga cagttgacga
    49861 actgtcagtt cttgctcatc tccacaaaaa tctggacgac taattccttt ttctatccga
    49921 atctctttaa ttttttgacc aattaacatc agacgcctcc tcttctacct gcttcgaaaa
    49981 atactgtgaa acttaaaaaa ttgtaacggc tacatctttc ctactcataa gatttcatag
    50041 cttcttccac ttctgccaaa gtaaccccaa acaactctag gcgtttgagg agttgcttgc
    50101 cgttggaata gccgattcgg agagtctctc cgagatattc tctacgctta cggctgtctg
    50161 cccctgctag aaaaccaagg cgaatcaagt cgctacgact aatgtcaaac tgactctcat
    50221 gttcaaattg ttctgtcacc tgagctagag ccgttttcag gtcttcatag ctggcatgct
    50281 caattcccag agaacgcccc ttggtcttgg acttgggaac agcttcatct cgcttgagaa
    50341 aggcatgctg aactgttgga atggccgtca taatcatgcg ccgaatccgc tccccattaa
    50401 aatctgggtc tgtaaagaca atgactccat gacgttggtg tagacgctga attcgctcta
    50461 tatcctgatc attgatggca gaacctcgtg tctcataggt ctccacatcg aaataacgct
    50521 tgagattgac cgtatcatcg cgaccttcaa ccacgataac ttgagaaatt ttctctttca
    50581 ttacttgctg tccaatccaa aaattcgttc tgcatttgca gtcgttgcta ccgccagctc
    50641 ttctgtcgtc ataccacgca agtcagcgat aaagtcgacc acatagcgag tataggctgt
    50701 tttattttca cgaccacgct tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa
    50761 aatcttgtcc aaaggtaact ctttagctgc ttcttggagg tcagttgcct tcttgaaagt
    50821 caccactcct gagaaggaaa tggtcatacc aagatccaca aacttctctg cccactcaag
    50881 cgtccctgaa aatgaatgca tgataccacc acgaggacca acgccctcac tcttgataat
    50941 ctcataggta tcttccagcg catcacgggt atggacaaca aaaggcaaat ccaagtcctt
    51001 agatagctga atctgacgac gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca
    51061 atggtagtct aagccaattt cacctagagc cacaaccttg ggatgtttta acttatccaa
    51121 caagtaagcc tcaacttcct ctgtataagt accagcttct gtaggatgcc aaccaatagt
    51181 cgcatagagc tgctcatact catctaccaa ctccaaggca cgctcaatcg tcggtttatc
    51241 aaaaccaaca atattcatct gtatcacacc catctcagca gccaaggcaa tttcttctgc
    51301 ctcacgacct gcaaattctt ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc
    51361 taacctcgtt ttctatcttc tattatacca aaaaagagga ggagcaccta atttttcggt
    51421 ttcccctcct ctcttcaata gagagctatt ctgctatctt ttctatccga tattgcccat
    51481 ctcctattcc acagttagag acagaagaga ttggctacat tgatagaata ttcctattca
    51541 gctaaagtat gtgattatct tgggttctca cttttctcac ccatcactag gattgatgac
    51601 ttctcaaaat cccccttata atctaacttt aagtagagaa tagaattttc tagctgttct
    51661 attttctacg tctagtcttt cttcctagca aagcaaaacc acttgttgcc accactagac
    51721 caagactagc aagtgctgca cttgatgctg aacctgtgtt aggtaattgt ttgccagcag
    51781 gtgactggta ggtaacatct tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct
    51841 taggagcagc attaggagcc actagtctct taggaactgt aaccatggca atggcttgca
    51901 ctccaatcgt ttctgcttcc ttcacatctt ccatagtttt cgcattttca atctctttga
    51961 gagctgcttg tttttctgct tccactcttg ctaaaagttc tgctttttct ttatcagaaa
    52021 gcggtgcgcc tttgatttca tcctgcttgt ccttggctgc tttttcaatg gcatttttag
    52081 ctgattcttt ttcagtagct aattgcttag aagcttgtga ttgagctgag ttttgtgaac
    52141 ctgtgtgagc tgatccaccc gcctggctac caccgcctgc attcgcatta gcatctgagc
    52201 ttccagtatt gcctccctta tctccacctg gtgtattttc tagcttatac tctggtgtag
    52261 cttcttgagt tacagattca cctttcgcag attgttgaac tgtatctttt cctagaatcg
    52321 tcactactga accatctggg aatgtgattg ttgctgtacc atctccagct acattgattg
    52381 tcgctccgtc taatgctgaa ccatttgctt gtaaaatagc aaccttaact ttttcttcat
    52441 ctgttaaatg agttatatct tttacatcta ctctttgagc aggtgcttta acagttgatt
    52501 tttcagcagt cggtttagtg ctatcttgtg cttttggatc ttgtgctacc aattgatttc
    52561 ctggaattgt aatagctgaa ccatctttaa agacgattgt cgctgtgcca tctccagcta
    52621 cttcaacttt atagtaaaat gaaataataa caggacaaat cgatcaggac agtcaaatcg
    52681 atttctaaca atgttttaga aatagaggtg tactattcta gtttcaatct actataacat
    52741 cgcttccgaa tccatttgca tctactgaac ttttttacaa aaataaaaat cagtagactc
    52801 gagttcctac tgatttttga tagaattcgt ttggattatg cagccaaaac tttgcgtcct
    52861 ttacgacgac gagctgccaa tacgcgacga ccatttttag ttgacatacg gttacggaat
    52921 ccgtgtttgc gcgcacgacg aagtttactt ggttgataag tacgtttcac gatgaatacc
    52981 tcctcataga ttttgtattc gtttagccgg ctataaagtg atcagttact aaacatactt
    53041 tactattcta tctgattctt tcacttttgt caatagctct aggcaaatgt ttccagcttt
    53101 ttcgaatgca agccctatct acgatactgt ttcaagaaac gagtcatctt ttcttggatt
    53161 tgggctaact catcaacacg aggaaggtaa acgatacgga agtggtctgg ttcctgccag
    53221 ttaaagcctc gaccatgaac caagagaacc ttttcctgct tcaagaaatc aaggacaaac
    53281 tgctcatcat catcgatacg gtacatattg cggtcgattt ttgggaagat atagagcccc
    53341 gccttgggtt taacggcaga caaacctgga atatcttgaa tggcattata gatgaaattt
    53401 ctttgctcgt agattcgtcc accaggaaga agcaattcat cgactgattg gtgacccccc
    53461 aaggaagttt gtacgacttg ttgggccaaa acgttagagc aaaggcgcat attggacagc
    53521 atattgagcc cttcgatata gcccttaaca tgagtcttag ggccagacaa gaccatccaa
    53581 cccacacgga aacctgctat gcggtgggat tttgacagac cattcatgct gacacagaag
    53641 acatctggtg ccaagctcgc cacaggcgta tgcacatgtc cgtccattac catgcggtca
    53701 tagatttcat ccgcaaagat aatcaaatcg ttttgacggg caatctcaat aatctccagc
    53761 aagagttcct taggataaag ggctccagtt gggttatttg gattgataag gacaattgcc
    53821 ttggtattgg aagtgatttt tgacttgata tcgtcaatat ctgggtacca ttccacagct
    53881 tcatcacaga tatagtgaac ggcatttcct ccagctaggc tgacagccgc cgtccataga
    53941 ggatagtctg gcattggcac taagacctca tccccattgt ccaaaagccc ctgcatggac
    54001 atgacaatca actcactgac accatttcca aggtaaatat catcaatatc tacgtttggg
    54061 aatttcttca gctggcaata ctgcatgatg gccttacggg ctgagaaaat ccctttggag
    54121 tcagaatagc cttcactatc acgcgcattc ataatcaagt catgaatgac ctcgtctggc
    54181 gctgtaaagc caaattctgc tggatttcct gtattcagac gtaaaatctt ttctccattc
    54241 gctcgcatcc gcatggcttc ttccaataca ggaccacgga tatcataagc aacatgctct
    54301 aacttactag acttgttata ttctttcatc ttgtttcctc aattcatcag gatagtaaca
    54361 ttataccact agaaagagaa tgcgacaagt ttactgaaat gtgttactag tttcgtatag
    54421 aagaaaaacc ttgctaaagg cgaggttaag aacgtagaga tagcaggtat tttgcaaaga
    54481 cacatcacat accaaaagat aaacctagaa aaagcaagcc tagaaaggag tcataaagaa
    54541 gattaaacat gaggaaaagc ccccatatca tcaagtaatc ccaacgccca cttcgttttg
    54601 caactagaaa taagattaga tggtagagta catgaaagac taaaaatcca ataaaacttg
    54661 gataaagaag cggtaccaga ctctctaatt gccagatcat gatcacttct accaagactg
    54721 aaactaggat aattccataa taaaggaaat ttgatttttg aaaagagttt ttcatcattc
    54781 tcccttcctt cacttctttc ctgctatcct ttcttttatt ttatcatata tttatataga
    54841 ttttaagccc taatattctt ttgaaaaata ctttttttgc tttacttcta tagtgaaaag
    54901 gtttacaatt atagtaagaa aatttcagga ggtttcatta tggcacaacg ttaccaaaat
    54961 atcatggtcg caatcgatgg ttctaaggaa gcggacttgg cttttgtcaa gggagttcat
    55021 tctgctctac gaaacgacgc taaactcacc atcgcacatg tcattgacac acgcgctctc
    55081 caaagcgtat ccacctttga tgctgaagtt tacgaagaac tccaagtcga cgctgaaagt
    55141 ctgatgaaag agtacgaaaa acgtgctaaa gatgctgggg tagcagatgt tcatatcgtc
    55201 attgaaatgg gaaatccaaa gaccctgcta gcacgtacta ttccagatgc cgaggaagtg
    55261 gacctcatcc tcgttggcgc aactggtctc aacgcctttg aacgcctctt ggtcggctct
    55321 tcatctgaat acatactccg ccatgctaag gtcgatttgc tggttgtaag agaacaagaa
    55381 aaaaccttat aatcacaaag aaaaggagcc cctagctcct ttttgtttac gatttatttc
    55441 tctctttatg gcgttcgtaa gccttgagct ggcgctgcag ttccttttta atagcaggtt
    55501 ctggagcata tttttcttcc caattatctg gttttaagat tttatgggtc actggatcaa
    55561 aatgagcctt accatctgga aaaattttcc ccatattggc ctgatggaca atatcaaaaa
    55621 tacgttctgg gtccaccccc atcaagacaa aactgccgta ggtgaagtaa agcatgtcaa
    55681 tcaaggcatc cacttgccct atcaaatctt gctgagcagg tgtcttcttg gctactttat
    55741 ctgctgcctt atcaagggcc tgatgaagtt gcgatacagc ttgaccaaaa tcttcttcag
    55801 aaggactggc tgctcgaaca aactccacca attcttctat tttaaaacca gccctatggg
    55861 ttgcaccctc taaatcccaa gctcgaggtt cttcttgggt tcgttcatcc atcatgtggt
    55921 ggaaggtctt gaccttattg aaatgatagt cacggctgac aaagactttt tctgaagaca
    55981 aaacaccaaa atgttccaag gccttgtgga tcccatcttg ttgattgcta gtggtaatgt
    56041 gcttggcagc ttccttgaca ctgctactac catttcccat agcgaccgac ataccaacgc
    56101 cagccagcat ttcaaggtca ttatctgagt caccaaaagc catgacttgg ttgaggtcaa
    56161 agccatattc tttcccaact cggcgaatgc cttctaattt agaatttccc tgattgatga
    56221 catccgatgc aaaaggattg ctacgtgtca atttcaagtc ttcaaaatca gctgccgcct
    56281 tctcagattc ttctggtgtc atcagcatca aaacttggta gataggctga ttcatcaggt
    56341 gaagcaggtc ttcttccttt tggggaacaa tcttgctgac catgcgatta aaagactgac
    56401 tcaccgtccg agttaaaaca gagggaacga agcgactaat tcgttgagaa aaagaaccca
    56461 gaccaaagga catgatttta gaacccaaca tggcatcctt ggtccctagg gcaatctccg
    56521 tgccctcttt tttagcatag ctaattagat ggcgcaaatg taacttagaa atagggctcg
    56581 tgaacaagac tctgtcttta ctaaagatat actggccatt ataggttacc gcaaaatcca
    56641 gatccaaatc gtccatcaat tccttaacaa aaaaaggtcc tcgccctgtc gctacgccaa
    56701 ctagtacccc ttgttctttg acaatcttaa tcgcgtcctt agtggatttc aaaacactct
    56761 tgcgattgtt gaccaaggtt ccatcgatat caaaaaaaac agctttgact tccatcctat
    56821 cccaatctcc ccttttgtga tacaatgatt ataccacatt tcagaaagag tgagtaaatc
    56881 atgcctaaga aaatccttgt tttacatacg ggtggaacta tttccatgca ggccgatgct
    56941 tctggcgctg ttgtgacgag ttcagataat cccatgaacc atgtgtccaa cccacttgaa
    57001 ggaatccaag tccacgcctt ggactttttt aaccttccaa gtccccatat caaacccaaa
    57061 catatgctgg tcctctacca gaaaattaaa gaggaagcag ataactacga tggagtggtg
    57121 atcacacacg gaaccgatac tttagaggaa acagcctatt tccttgatac catggaagtt
    57181 ccccatatgc ctatcgttct aacaggagcc atgcgtagct ccaatgagct cggtagtgat
    57241 ggtgtttata attacctaag tgctttacga gtggccagtg atgacagggc tgctgacaaa
    57301 ggagttttgg tcgttatgaa cgatgaaatc cacgctgcca agtatgtcac caaaacacat
    57361 acgactaatg tcaacacctt ccagactcca acacatggcc ccctcggtct catcatgaaa
    57421 caggaaatcc tctacttcaa aacagctgaa cctcgtgttc gctttgacct tgatcacata
    57481 caaggtttag tccctatcat ctcggcttat gctggtatga cagatgagct gattgatatg
    57541 ctggatttag aacacttgga cggtttgatt atccaagcct tcggagctgg taatattccc
    57601 aaagaaacgg ctcaaaaatt agaaagcctt ctgcaaaaag gaatcccagt cgctctggta
    57661 tcacgatgct ttaacggtat tgccgagcct gtttatgcct accagggtgg gggcgtacag
    57721 ttgcaaaaag caggcgtttt ctttgttaaa gaactcaacg cccaaaaagc ccgcttgaaa
    57781 ctcctcatcg ccctcaatgc cggactaaca ggacaggctt tgaaagacta tatggaaggc
    57841 taatactctt cgaaaatctc tgcaaaccac gtcacgtcgc cttaccgtat gtatggttac
    57901 tgacttcgtc agttctatct acaacctcaa aaacatgttt tgagctgact tcgtcagttc
    57961 tatctgcaac ctcaaagcag tgctttgagc tgacttcgtc agttctatct acaacctcaa
    58021 aacagtgtgt tgcgcagcct ttaaccagcc gcctagtccg ctctatggta ttcattaagt
    58081 caacatctct tgtttaagag cacaaaatca ggaaatcttc tcgattccct gattttttct
    58141 atttacgttt tcgtgttgag ctacgttctg tcaaaccatg aggtaagaga acttcacgtt
    58201 cttccaactc ttccttatgc ataatcttgg tcaacatacg catactaatg gcaccaaggt
    58261 cataaagagg ttgggcaatc gttgtcaagt ttggacgggt aaagcgtgag atttgtgaat
    58321 catcactagt aataatttca aaatcttctg gcacagaaac acccttatca gccaaaccgt
    58381 tcaagactcc tgctgccaac tcatcacctg tcacaactgc tgcagttgca tttgatgaaa
    58441 tcaaacgctc tgctaaggcg taaccatcat catagctata tttagattca aataccaaac
    58501 cctcactata agcgattcct gcttttttca aggtttcctt gtagccaact aaacgaacct
    58561 taccattgat gtcatccact agcggaccgc taacgaaagc aatacgctca ttttctttag
    58621 caaggtaact cactgcatca attgttgctt gcttatagtc aatattgaca cttggcaact
    58681 ggtgctcaac atcgacagtt cctgcgagaa caatcggagt acgtgaacgc gaaaattctg
    58741 agcgaatttt atctgtcaag tgataaccca tatagataat gccatctacc tgctttgaaa
    58801 agagggtatt gacaacagaa acttctttct cgttatcttc atcgctatta gctaggacaa
    58861 tattgtactt gtacatttct gcaatatcat caatcccctt agccaaactc gaaaaataac
    58921 cattggtaat atttggaatc acgacaccga cagtggttgt ctttttactt gcaagaccac
    58981 gcgcaactgc atttggacga taatccaagc gatcaattac ctctagcact tttttacggg
    59041 tattctcttt tacattttta ttgccattga ccacacggct gaccgtcgcc atggaaacac
    59101 ctgcttcacg agcgacatca taaatggtta ctgtatcatc tgcattcatt ccttttcctg
    59161 tcctttctat ctcacacatt cttttacaag tagaggtact gattgaagct ctatatctac
    59221 ttacaaaagt gaagatgtga aaatttcgtt ttcatatttc tacttattcc attctatcac
    59281 taattgtaaa cactttcaag tgttttttga agattgattg aaaaaatttc atagaaaacc
    59341 taggtttagc tccttgctac caccttagac taaacaaaaa ggaggaaact aagccctcct
    59401 aaagttatag taaaatgaaa taagaacagg ataaatcgat caggacagtc aaatcgattt
    59461 ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta taggtattgt
    59521 tccattcact accgtcaatt ttagcacata gtcttcatga aaatattata tcatcataac
    59581 caaccagatt cttttgcgat attagctgcc tctgttcgat taccagcatc caattttgaa
    59641 agaatattgg tgacatagtt tcgaatagtt ccgtttgaga ggtaaagctg atctgcgatt
    59701 tcttggttgg ataagccccg ggcgatcccc tttaagacag caatctcttg ttctgtcaac
    59761 ggattgggac gggtcatcac cacttccatc aattcaggcg aatactcctt gcgtccttcg
    59821 aggacggtgt gcaaggtttg catgaggtct gcaacgcttc gttcctttaa tacataagca
    59881 tccactccag ccttgaccgc acgttcaaaa tacccagcac gcttgaaggt cgtcaccaca
    59941 accacctttg tttcaagcct ttctgatcgt atccactcca agacttcaag acctgtctta
    60001 acaggcattt ctacgtcaag gatggcgata tctacagact ccttttctaa tagttggatt
    60061 gcttcttgcc cattcttggc ttgaaggaca gactccacat ctggttgaag cgtgagcaat
    60121 tgacacatgg catctcgcaa catactttga tcttctgcga ctaatacttt catcttagtt
    60181 tctctcctta taaggtagtc gaacttgcac ttccgttgga tgtttctgac tgattacact
    60241 tacttctcct gaaaatggaa aaacacgatc tcggattgta tggagctcat ctccttttag
    60301 aaaagcaaag ccgcagccat catcacttac tgttaaaatg agttccttct ctgtccgttc
    60361 taattttaag taagctttag acgctttggc atgtttgatg atattggtca ccaactcaag
    60421 caaaatcata gaagccattg actccaattc ttgagtaagg ctagcagtat ctagttggtt
    60481 atccgtttcc acctcaattc cagcaatttc taacatcttt ttcacagtct ctagttcgga
    60541 tgtcaaagtt ctagacttaa gattttccac aatggttcga acttcacgca ttgattcttt
    60601 gctaatttgc tgtatttctc ttaattcctt ttccacttgt ggataagcct gcatttgaaa
    60661 tagctgcaag gctagatctg tcttgacact aagcatagca aaggtatgtc ccagactatc
    60721 atgcaaatcc tgaccgatac gattgcgctc attttctgct agcaatagat ttatctgggt
    60781 attttgcttg acctgagctt ctttcaaatc ctcgacaagg cgaattcgaa ccgagcccaa
    60841 agtcatcaaa tcgacaaaag taagaattac aagcatatag actagaaact caacttcgat
    60901 tctctgaaaa atcaaaagtc gccccacaac aaggacttga gcaaggagaa atgtccatac
    60961 atgtaaagac tttaaactac gtacgccaaa atgataaatt aagagattgg aaaggaaaaa
    61021 gaaaaaccag atataattcc cagcaacaaa ggcggtattc ccagctacat agaccagcat
    61081 gatcccccag aaaagccatg atatgcgctg gttcttagtt attaaaacac ccaaatacgt
    61141 cactacaaat agaatatcaa ccaataaatg ccaagcagga agctccccag tcactacagg
    61201 taggatgggg aaaatcataa aaattaaact tgcccaaaac atatagtgta tgcttttcag
    61261 tctttcaagc attaagcatt ctccttatga ccttgaaggt aaatggtcaa accaaacaaa
    61321 actgctgaaa aaacaagtag ataaactgtg gctgatagat tgatgccacc ctcgtttaag
    61381 aaggtcttga gcaactccat caattgatag gtcgggagac acttaccaac tgcttgcatc
    61441 cagtctggaa ataaagaaat gggcatccag agtccgccta aaacagccaa tcctagataa
    61501 agaagattgc ccacaacaga catcagctga ctagttggta agagagtcaa ggtcaagcca
    61561 agtgctacaa aagcaatact ccccacaatc agcaaaatcg cagctccaac ccattttact
    61621 agaggcatgt ctacacctct tacaaaatgt ccaactgtaa aaacaaccag aattgagacc
    61681 aaataatcaa ccagcatact tgttatcttt gatagataat attctaccat atttacaggg
    61741 ctatgacgca atgttttctg ccagttgttc atcttatcgg tatgtaaaac agctggaaat
    61801 gagaggatag ttgtcgacat catggaaaag gcagtcatgg agatgaggta atcacgcata
    61861 aaattcgcga gttcacctgg tgtgtcctga tagataccag aaaaaaataa atagaaagcc
    61921 gtcggcatcc ctaccgacaa tagataatag attaattgtc gtttggtcaa taaaaattct
    61981 atcttactaa gtgctatcca tcgtttcatc ttagttatct cccttctgcg tctcttcaaa
    62041 gattgtattc aacaaactac gattattaac ttcgatttct tgcatcctac atcctgcttg
    62101 ggctaatagt tcccagaaag catctgcttc tcgagtgact acttgtaaag aatcttgctt
    62161 tagggtccag ttttcaacca aatttgactg ctctacgact tccttgtaag ctataggaag
    62221 gataaagtgc ttttctattt cctcgctacg catagctaga ggcgtcgtat ctcgaatcaa
    62281 ctctccctta tttaagagca aaatgcggtc tgcagtgtgt tccacttcct caatataatg
    62341 ggacgaatag agaatggtga ctccttgcgc ttttaactcc tggacaattt cccaaaaacg
    62401 ttgacgagtt gaggtatcca tggacgcagt aggctcatct aaaaaaacaa tctttggtcg
    62461 cccaattaag gtcaagacga aagaaaagag acgcttttga ccgcctgata atttttctgc
    62521 caactgttct ttttgttgct tgacaaactg caatagttga tcaatttcct gattgctcaa
    62581 aggatttgga tagatacgtt gaaagaaagc aatcaactct ttaactttta atttctgaac
    62641 gattacattt tcttgaggga ggtaagccct agtatagtct aacttagaac tcgtcactgg
    62701 taaaccttga atagatactt gaccgcttgt gaccagttta tctccaagca aacaatctaa
    62761 gagtgttgtc tttccggcac catttggacc aattaaggca acacattcac catcgttgat
    62821 ttcaaaggag atattccgca aaatttcctt gtcttttatt ttcttactca atttctcaac
    62881 tttaaccacc gtcatgagac tctcctttca accactccat tcccataagg aaaacgacga
    62941 aaatcataaa tccaaacccc aaagcaccac gaatgaattg gcgaagcaag gcttgatcaa
    63001 accaatcagt aaacatttcc actaaccata ccaagagtga caggccgata aagaaataga
    63061 tgatccctct cttcattcct caaactcctt tttcacatct ctgactaatt tcaaaccttc
    63121 tctaacaagc caagacatga ttccaaagcc agcaaagacc ttccaaggaa aatggtagaa
    63181 atcctcatcc aatcccgaaa acatgagata ggtcataact cctgctacta ctaaacttac
    63241 tgcgataatc attttatttc tcatctcttc ttcccccatt tcatactaca attatagtct
    63301 tttaaaatca gaggagacag aagcttctgt cactaaaaaa tatgacaaat gtcataaaaa
    63361 attctgttca aaacaagcaa gatacactat acaataaaac acaatcagaa aaatctaagg
    63421 caacttcctc aaaagagata tcaaacccaa ttcacaccat aatgtaaact aatacttatt
    63481 taaaatcaaa aagagtaaaa atttttatca gacaaacaca tatatagtgt attgaatcta
    63541 taacagtagg ccttaaatac taaaatattt ctataaatta atttaacttt cctgatagaa
    63601 ctgttcatat cttatttcaa ttctctatat tatacgttga accaaaccct tctattgctt
    63661 tcttaaaaat ttataagagt tataaaatct gttaaatttc aatgtgtata tctaaactac
    63721 ggtatttatt gaaaagactg gagacaaaaa gtatacgctg ccaaaatgaa ttactgaaaa
    63781 tcaaaaaaga gagaaccaaa ctgattccct cttaatgtat ataatatcta gttttaaaaa
    63841 tacacactca catatctctg t
//
LOCUS       DBEJNA010000007        60540 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEJNA010000007 DBEJNA010000000
VERSION     DBEJNA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 60540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.07"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            497..1540
                     /locus_tag="ACL3JB_000498"
     CDS             497..1540
                     /locus_tag="ACL3JB_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR0685296.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1707..3794
                     /gene="topA"
                     /locus_tag="ACL3JB_000499"
     CDS             1707..3794
                     /gene="topA"
                     /locus_tag="ACL3JB_000499"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0685297.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            4015..4374
                     /locus_tag="ACL3JB_000500"
     CDS             4015..4374
                     /locus_tag="ACL3JB_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0685298.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4467..5099
                     /locus_tag="ACL3JB_000501"
     CDS             4467..5099
                     /locus_tag="ACL3JB_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0685299.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILKYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5143..5799
                     /locus_tag="ACL3JB_000502"
     CDS             5143..5799
                     /locus_tag="ACL3JB_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0685300.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5869..6912
                     /locus_tag="ACL3JB_000503"
                     /pseudo
     CDS             5869..6912
                     /locus_tag="ACL3JB_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6924..7961
                     /gene="leuB"
                     /locus_tag="ACL3JB_000504"
     CDS             6924..7961
                     /gene="leuB"
                     /locus_tag="ACL3JB_000504"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGR0685301.1"
                     /translation="MAKKIVALAGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDYILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7958..8227
                     /locus_tag="ACL3JB_000505"
     CDS             7958..8227
                     /locus_tag="ACL3JB_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0685302.1"
                     /translation="MKLDEKIALVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALICGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8231..8590
                     /locus_tag="ACL3JB_000506"
     CDS             8231..8590
                     /locus_tag="ACL3JB_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0685303.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPIDQATVDLEQQKIISPVEEFTFEIDSEWKHKLLNTLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8752..9322
                     /locus_tag="ACL3JB_000507"
                     /pseudo
     CDS             8752..9322
                     /locus_tag="ACL3JB_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004915491.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9416..9481
                     /locus_tag="ACL3JB_000508"
                     /pseudo
     CDS             9416..9481
                     /locus_tag="ACL3JB_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9644..11575
                     /locus_tag="ACL3JB_000509"
     CDS             9644..11575
                     /locus_tag="ACL3JB_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0685304.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPDYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11562..12878
                     /locus_tag="ACL3JB_000510"
     CDS             11562..12878
                     /locus_tag="ACL3JB_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0685305.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGAQLKKWSIRIPQNASFYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            13044..14030
                     /locus_tag="ACL3JB_000511"
     CDS             13044..14030
                     /locus_tag="ACL3JB_000511"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0685306.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            14094..14165
                     /locus_tag="ACL3JB_000512"
     tRNA            14094..14165
                     /locus_tag="ACL3JB_000512"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14127..14129,aa:Arg,seq:ccg)
     gene            14348..15046
                     /gene="rnc"
                     /locus_tag="ACL3JB_000513"
     CDS             14348..15046
                     /gene="rnc"
                     /locus_tag="ACL3JB_000513"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0685307.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            15037..18576
                     /gene="smc"
                     /locus_tag="ACL3JB_000514"
     CDS             15037..18576
                     /gene="smc"
                     /locus_tag="ACL3JB_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0685308.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18573..19367
                     /locus_tag="ACL3JB_000515"
     CDS             18573..19367
                     /locus_tag="ACL3JB_000515"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0685309.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19367..20185
                     /locus_tag="ACL3JB_000516"
     CDS             19367..20185
                     /locus_tag="ACL3JB_000516"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0685310.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPIKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            20189..21466
                     /gene="ftsY"
                     /locus_tag="ACL3JB_000517"
     CDS             20189..21466
                     /gene="ftsY"
                     /locus_tag="ACL3JB_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0685311.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21512..22999)
                     /gene="zwf"
                     /locus_tag="ACL3JB_000518"
     CDS             complement(21512..22999)
                     /gene="zwf"
                     /locus_tag="ACL3JB_000518"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0685312.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(23148..23888)
                     /locus_tag="ACL3JB_000519"
     CDS             complement(23148..23888)
                     /locus_tag="ACL3JB_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0685313.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23888..26053)
                     /locus_tag="ACL3JB_000520"
     CDS             complement(23888..26053)
                     /locus_tag="ACL3JB_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0685314.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26226..27179
                     /locus_tag="ACL3JB_000521"
     CDS             26226..27179
                     /locus_tag="ACL3JB_000521"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0685315.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27256..29244
                     /gene="uvrB"
                     /locus_tag="ACL3JB_000522"
     CDS             27256..29244
                     /gene="uvrB"
                     /locus_tag="ACL3JB_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0685316.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29254..29817
                     /locus_tag="ACL3JB_000523"
     CDS             29254..29817
                     /locus_tag="ACL3JB_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0685317.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29783..30271
                     /locus_tag="ACL3JB_000524"
     CDS             29783..30271
                     /locus_tag="ACL3JB_000524"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685318.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            30345..30812
                     /locus_tag="ACL3JB_000525"
     CDS             30345..30812
                     /locus_tag="ACL3JB_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0685319.1"
                     /translation="MFRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30809..31324)
                     /locus_tag="ACL3JB_000526"
     CDS             complement(30809..31324)
                     /locus_tag="ACL3JB_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0685320.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31336..31863)
                     /locus_tag="ACL3JB_000527"
     CDS             complement(31336..31863)
                     /locus_tag="ACL3JB_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0685321.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(32145..32708)
                     /locus_tag="ACL3JB_000528"
     CDS             complement(32145..32708)
                     /locus_tag="ACL3JB_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0685322.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32692..33243)
                     /gene="coaC"
                     /locus_tag="ACL3JB_000529"
     CDS             complement(32692..33243)
                     /gene="coaC"
                     /locus_tag="ACL3JB_000529"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0685323.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(33255..33944)
                     /gene="coaB"
                     /locus_tag="ACL3JB_000530"
     CDS             complement(33255..33944)
                     /gene="coaB"
                     /locus_tag="ACL3JB_000530"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0685324.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREVTNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            34174..35844
                     /locus_tag="ACL3JB_000531"
     CDS             34174..35844
                     /locus_tag="ACL3JB_000531"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0685325.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            36173..37348
                     /gene="mutY"
                     /locus_tag="ACL3JB_000532"
     CDS             36173..37348
                     /gene="mutY"
                     /locus_tag="ACL3JB_000532"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0685326.1"
                     /translation="MLDLKEHGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37403..38107
                     /gene="yycF"
                     /locus_tag="ACL3JB_000533"
     CDS             37403..38107
                     /gene="yycF"
                     /locus_tag="ACL3JB_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0685327.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            38100..39449
                     /gene="vicK"
                     /locus_tag="ACL3JB_000534"
     CDS             38100..39449
                     /gene="vicK"
                     /locus_tag="ACL3JB_000534"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0685328.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39451..40260
                     /locus_tag="ACL3JB_000535"
     CDS             39451..40260
                     /locus_tag="ACL3JB_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0685329.1"
                     /translation="MSKIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            40351..40593
                     /gene="relB"
                     /locus_tag="ACL3JB_000536"
     CDS             40351..40593
                     /gene="relB"
                     /locus_tag="ACL3JB_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0685330.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            40595..40849
                     /locus_tag="ACL3JB_000537"
     CDS             40595..40849
                     /locus_tag="ACL3JB_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0685331.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            40896..41639
                     /locus_tag="ACL3JB_000538"
     CDS             40896..41639
                     /locus_tag="ACL3JB_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HGR0685332.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     NSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSEKIEELH"
     gene            complement(41940..42926)
                     /locus_tag="ACL3JB_000539"
     CDS             complement(41940..42926)
                     /locus_tag="ACL3JB_000539"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0685333.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            43120..45588
                     /gene="gyrA"
                     /locus_tag="ACL3JB_000540"
     CDS             43120..45588
                     /gene="gyrA"
                     /locus_tag="ACL3JB_000540"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0685334.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            45588..46331
                     /gene="srtA"
                     /locus_tag="ACL3JB_000541"
     CDS             45588..46331
                     /gene="srtA"
                     /locus_tag="ACL3JB_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0685335.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
     gene            46575..47372
                     /locus_tag="ACL3JB_000542"
     CDS             46575..47372
                     /locus_tag="ACL3JB_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0685336.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            47520..48779
                     /locus_tag="ACL3JB_000543"
                     /pseudo
     CDS             47520..48779
                     /locus_tag="ACL3JB_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            48875..50149
                     /locus_tag="ACL3JB_000544"
     CDS             48875..50149
                     /locus_tag="ACL3JB_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0685337.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRQEKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            50159..51037
                     /gene="truB"
                     /locus_tag="ACL3JB_000545"
     CDS             50159..51037
                     /gene="truB"
                     /locus_tag="ACL3JB_000545"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0685338.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLYEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            51278..51580
                     /locus_tag="ACL3JB_000546"
     CDS             51278..51580
                     /locus_tag="ACL3JB_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0685339.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            51688..52326
                     /gene="udk"
                     /locus_tag="ACL3JB_000547"
     CDS             51688..52326
                     /gene="udk"
                     /locus_tag="ACL3JB_000547"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0685340.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            52454..53794
                     /gene="xseA"
                     /locus_tag="ACL3JB_000548"
     CDS             52454..53794
                     /gene="xseA"
                     /locus_tag="ACL3JB_000548"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0685341.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            53772..53984
                     /locus_tag="ACL3JB_000549"
     CDS             53772..53984
                     /locus_tag="ACL3JB_000549"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0685342.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            53981..54856
                     /locus_tag="ACL3JB_000550"
     CDS             53981..54856
                     /locus_tag="ACL3JB_000550"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0685343.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            54849..55664
                     /locus_tag="ACL3JB_000551"
     CDS             54849..55664
                     /locus_tag="ACL3JB_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0685344.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            55657..56088
                     /locus_tag="ACL3JB_000552"
     CDS             55657..56088
                     /locus_tag="ACL3JB_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0685345.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            56095..57762
                     /gene="recN"
                     /locus_tag="ACL3JB_000553"
     CDS             56095..57762
                     /gene="recN"
                     /locus_tag="ACL3JB_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0685346.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDKQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSYLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            57764..58492
                     /locus_tag="ACL3JB_000554"
     CDS             57764..58492
                     /locus_tag="ACL3JB_000554"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0685347.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            58571..60394
                     /gene="lepA"
                     /locus_tag="ACL3JB_000555"
     CDS             58571..60394
                     /gene="lepA"
                     /locus_tag="ACL3JB_000555"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0685348.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT        18524 a        10719 c        13673 g        17624 t
ORIGIN      
        1 tttagcagcc aaggtgcact gttatagatt caatacacaa taatttagtg taattgagaa
       61 aggagaaatg attgtgattg atgttggcta ggttatgttc aatgattcct accgtctcaa
      121 atcttgtcag taaggaaaaa taaattcttc aaaagtagag attacaaggc ttgtttaaga
      181 aagaattcaa agaccttgac aaataaaaat aaaatggtta ttataaaaaa tggtctgaaa
      241 tagatgatga tacttttcga aaatcttttt acgtcagctc agctttgcct tgctgtgttt
      301 tgagcaagct acggttagct tccgagtttg attttcattt actagaaatg aaactgatga
      361 gagatatcag tagacatctg agttaggata ttatggaaaa tgataaaaag agctcgtgag
      421 attggcatat cagactacta aagtattgag tttgttagga ttttagcgac tagttagctg
      481 ggaaaggaag atatttgtga caaataataa actgtattcg ttgatagaat ttagaaataa
      541 aatatatgaa gaattagaac tttccagaag tgatttagcg attttactat gtgccatgct
      601 tatcgcctct atcggattaa atatggattc gactcccgtg attattggag ccatgttaat
      661 ctctcctttg atgacaccta ttctgggagt ggggctctct ctagctatat ttgattttaa
      721 attgttaaga aaatctttta aaatattagc tattcaaatt cttgccagtc taatagcttc
      781 aacactttat ttttatcttt ctcccatttc gtatgctagt tcggagattg ttgctagaac
      841 ctctccgact atttgggatg ttctcattgc ttttgtagga gggatagcag gtattattgg
      901 tgctaggaaa aaagagacca ataatattgt tcctggtgtt gctattgcaa ccgccttgat
      961 gcctcctctt tgtacagtag gttatgctat tgcttctgct aatctaaaat ttatcatagg
     1021 ctcctcttac ctattcctca tcaattgtag ctttattgtc attgcgactt atataggtgt
     1081 taggttgatg atggttaaga aacattattt taaagataat gaagaagact ctaaaatgcg
     1141 taggattttg cttctagttg ctgttttgct gatgattccg agtttcatct ctgcaacgac
     1201 tttagtgaga gaaacgttga aaaaagagtc ccttaagaaa tttatatcag agcagtttca
     1261 ggggtataat attttgaaaa aaacctattc taaaaagact cataccctaa agctaaccat
     1321 ttcaggaaat tatttgacag aagaagaact cgatatgatt tcaagtaaga gaggtgacta
     1381 tggtttaagt gatgtttctg ttcaagtttc acaattgtct gattcagaac aacttagtaa
     1441 ggaagagctg gtggagtatt tcttccagta tatcaaggat aaggaagcaa aagaaaagga
     1501 gaaagctaat aaatttgata cagagtctga ggagcaataa tttcttgaga atagctggtt
     1561 tctctcgtga gtcttctatg tatatcaaag gaagactgag gttttaagta taaaactttt
     1621 cttctattat agtagctaag tcttgacagg gttcaaaaaa tggtttacac tttataaagt
     1681 ttattacttt gaaaaggtgt gatactgtgg ctacggcaac aaaaaagaaa aaatcaacag
     1741 ttaaaaaaaa tctagtcatc gtggagtcgc ctgctaaggc caagacgatt gaaaaatatc
     1801 taggcagaaa ctacaaggtt ttagccagtg tcgggcatat ccgtgatttg aagaaatcca
     1861 gtatgtccgt cgatattgaa aataattatg aaccgcaata tatcaatatc cgaggaaaag
     1921 gccctcttat caatgacttg aaaaaagaag ctaaaaaagc taataaagtt tttctcgcga
     1981 gtgacccgga ccgtgaagga gaagcgattt cttggcattt ggcccatatt ctcaacttgg
     2041 atgaaaatga tgccaaccgt gtggtcttca atgaaatcac caaggatgca gtcaaaaatg
     2101 cttttaaaga acctcgtaag atcgatatgg acttggtcga tgcccaacaa gctcgtcgga
     2161 tcttggatcg cttggtaggg tattcgattt cgcctatttt gtggaagaag gtcaagaagg
     2221 gcttgtcagc aggtcgcgtt cagtccattg cccttaaact catcattgac cgtgaaaatg
     2281 aaatcaatgc cttccagcca gaagaatact ggacagttga tgctgtcttt aaaaagggaa
     2341 ccaaacaatt tcatgcttcc ttctatggag tagatggtaa aaagatgaaa ctgaccagca
     2401 atgacgaagt caaggaagtc ttgtctcgtc tgacgagtaa agacttttca gtagatcagg
     2461 tggataagaa agagcgcaag cgcaatgctc ctttacccta taccacttca tctatgcaga
     2521 tggatgctgc caataaaatc aatttccgta ctcgaaaaac catgatggtt gcccaacagc
     2581 tctatgaagg aattaatatc ggttctggtg ttcaaggttt gattacctat atgcgtaccg
     2641 attcgactcg tatcagtcct gtagcgcaaa atgaggcggc aagcttcatt acggatcgtt
     2701 ttggtagtaa gtattctaag cacggtagca aggtcaaaaa tgcatcaggt gctcaggatg
     2761 cccatgaggc tattcgtccg tcaagtgtct ttaatacacc agaaagcatc gctaagtatc
     2821 tggacaagga tcagctcaag ctatataccc ttatctggaa tcgttttgtg gctagccaga
     2881 tgacagcggc cgtttttgat accatggctg ttaaattgtc tcaaaatgga gttcaatttg
     2941 ctgccaatgg tagtcaggtt aagtttgatg gttatcttgc catttataat gattctgaca
     3001 agaataagat gttaccggac atggttgttg gagatgtggt caaacaggtc aatagcaaac
     3061 cagagcaaca tttcacccaa ccgcctgccc gttattctga agcaacactg attaaaacct
     3121 tagaggaaaa tggggttgga cgtccatcaa cctatgcgcc aaccattgaa accattcaga
     3181 aacgttatta tgttcgcctg gcagccaaac gttttgaacc gacagagttg ggagaaattg
     3241 tcaataagct catcgttgaa tatttcccag atatcgtaaa cgtgaccttc acagctgaaa
     3301 tggaaggtaa actggatgat gtcgaagttg gaaaagagca gtggcgacgg gtcattgatg
     3361 ccttttacaa accattctct aaagaagttg ccaaggctga agaagaaatg gaaaaaatcc
     3421 agattaagga tgaaccagct ggatttgact gtgaagtgtg tggcagtcca atggtcatta
     3481 aacttggtcg ttttggtaaa ttctacgctt gtagcaattt cccagattgc cgtcataccc
     3541 aagcaatcgt gaaagagatt ggtgttgagt gtccaagctg tcatcaggga caaattattg
     3601 agcgaaaaac caagcgtaat cgcctcttct atggttgcaa tcgctatcca gaatgtgaat
     3661 ttacctcttg ggacaagcct gttggtcgtg actgtccaaa atgtggcaac ttcctcatgg
     3721 agaaaaaagt ccgtggtggt ggcaagcagg ttgtttgtag caaaggcgac tacgaggaag
     3781 aaaagattaa ataagaggag gggcccgaaa gtaaatttca ggctcctttt ggttagaact
     3841 tgacaaaata catcatttta tgcgaaacta gaagaagatt attttatact caatgagaat
     3901 caaagagcaa attagaaagc tagtcgcagg ttgctcaaag cactactttg aggttgaaga
     3961 tggaagctga cctggtttga agagattttc gaagagtatt aactaggaga agttatgcgt
     4021 cttatctatc tgataattgg ttttttatca ctggccttgg ctattgttgg ggttgtttta
     4081 cccttgttgc cgacaacacc tttccttttg ttgtctattg cttgtttctc cagaagttcc
     4141 aagcgattcg aagattggct ttatcatacc aagctctatc aagcatatgt agctgatttt
     4201 cgtgagacca agtctattgc gcgtgaacga aagaaaaaaa tcatcgtctc tatctacgtc
     4261 ttgatgggaa tttctattta ttttgcacct cttttaccag tcaaaatcgg tctgggtgct
     4321 ttgaccatct ttattactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa
     4381 cagtagttat ttgccttgat aaaattgaaa gcatattcat aacaatatga tataataaaa
     4441 ttgaagtaat attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt
     4501 tacttgaaaa agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag
     4561 ttggtgggac aacacccagc tatggagtga ctaaggcagc ggttgaactg gcagctaact
     4621 acgatacaac catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgacc
     4681 tagaaattgc tatcatgcta gaagacattc gtttgactgc tcaggctgga agtcaagggg
     4741 ttgtatttgg agctttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa
     4801 ttgctgcatc aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg
     4861 aagatcaacc ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc
     4921 gtgctggtgt gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttga
     4981 agtacgctaa aggtaaaatt gaaattctac caggtggggg gattgacctt gaaaaccgtc
     5041 aaacctttat cgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa
     5101 aaatagaaag gaactgctag ctttgggtag cagttttcac ttatgtttga aatttttaaa
     5161 tcctatcaat ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc
     5221 tggacatata gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct
     5281 gataatgtga actttcaagt ctttgaccaa gagactggtg acctctatcc tcacgtttat
     5341 atggaaagca tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt
     5401 taccagattc ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt
     5461 atcatgactc aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg
     5521 cctgatacag ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa
     5581 atctcttgga ataagctgga aaagggcaga gaaggacaag tggaagcagt caacctcaag
     5641 catgaccaag tagctaattt gctttcacaa aaggggattt atccagcctt ccatatgagc
     5701 aagcgctact ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa
     5761 ttgatagaaa aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg
     5821 aactttcaat tagctaaata ttctttactg aagaaatttt cagaaaatat aggatttacc
     5881 acaccagagg aatgtggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt
     5941 cagatcatct attcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt
     6001 gctgctgtca agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga
     6061 gctgaaaatg ctgctttgga agaaattgca gtggctctca atattcgcca agattactac
     6121 caagtagaaa ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgc
     6181 ttctctggta ttccagttcc taaaaacaaa gccgtcgttg gtggcaatac cttctcccac
     6241 gaatctggta ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca
     6301 cctgaattgg ttggtgttaa gattccgctt ggaaaattat ctggtcgcca tgcttttgtt
     6361 gagaaactga gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct
     6421 aagttcaagg cactggccga taagaagtaa gaaatcacag atgcagatac tcgagctttg
     6481 gtagctggaa ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa
     6541 actcatgcag ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa
     6601 gtcgaattta atgcgacagg gcaaggttcc gttgaagcaa tctttaacgc tatcgataag
     6661 ttctttaacc aatctgttcg tttggtgtcc tacactatca atgcggtaac agatggaatc
     6721 gatgcccagg atcgggtttt ggtcactgtt gaaaacagag atacagaaac catctttaat
     6781 gcagcagggc ttgattttga tgtgttgaag gcttctgcta ttgtctatat aaacgctaat
     6841 acctttgttc aaaaagagaa tgcaggtgag atgggacgca gtgtttctta ccacgatatg
     6901 cctagtgtgt aaaggagaag gctatggcaa agaaaatagt agctctagca ggagacggaa
     6961 ttggcccaga aatcatggag gctggtttag aagttctgga ggctctagct gaaaaaacag
     7021 gttttgacta tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcagggc
     7081 ctcccttacc tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagcag
     7141 ctatcggtag tcctcagtat gatggagcag tggttcgccc tgaacaaggc ctgatggctc
     7201 tccgtaagga actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca
     7261 agcatttgtc accactcaaa ctggaacgaa ttgctggtgt agactttgtc gtggtgcgtg
     7321 aattgacagg cgggatttac tttggagatt atattcttga agagcgcaat gcgcgtgata
     7381 tcaacgacta tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa
     7441 gaaatcgcag aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac
     7501 tctggcggaa agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc
     7561 agctggtaga ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg
     7621 taacggagaa tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac
     7681 ttgaggttat gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc
     7741 acggttcagc acctgatatt gcaggtcaag gaattgccaa tcctacttcc atgattttat
     7801 cagttgccat gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac
     7861 gtgctgttga gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt
     7921 caacaaagga aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattgc
     7981 tctagtcctt ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa
     8041 ggcaaggaga agagcttggc gcatccaaga gaaaatctta ctcattttag cccttatttg
     8101 tggtggtttt ggggcctggt tagctggaat cacttttcac cacaagactc gaaaatggta
     8161 ctttaaaaca gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg
     8221 gaggtaatgg atggcagggt cttcgaggga acacgctgct tgggttctag cggactatgg
     8281 ttttaaggtc gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa
     8341 tggcctgttg ccaatcgttc agcctagaga ggttagagag aaattagccc agctaaaacc
     8401 aatcgaccag gcaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt
     8461 caccttcgag atagatagcg agtggaaaca taaactccta aatactttgg atgatatcgg
     8521 tattaccttg cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg
     8581 gcaggattag aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg
     8641 aattagagct taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga
     8701 ttcaacacat tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa
     8761 ggtgagggcg gatgtatcgt ttgccctact aaagttggtt acattatcat gaccagtgac
     8821 aaggcaggac ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt
     8881 gttctctgcg gtagcatgga tgaacttcgc gctttagcgc aactcaaccc agaaattgaa
     8941 gcattctact aaaaacattg ggatgaagat attcttcttg gttgtatcct tccttggaaa
     9001 ccagaagcct ctgaaaaact caaagcatac ggggatggcc gtgaagaact tatgactgat
     9061 gtacgtggta ctagctgttt tgttatcaag tttggaaaag caggtgaaca attggctgcc
     9121 aagctttggg aagaaggtaa aatggtctac gcctcatctg cttcaatgac aaaacgattg
     9181 aaactcgcta tgagagcaag gtgtaatggt gtctatggtc gataaggacg gcaaactcat
     9241 cccagaacaa ggaggagcac gttcaacttc accagcacca gttgtgatcc gtaaagggct
     9301 tgacattgat atagtaaaat gaagtaagag caggacaaat taatcaggac agtcaaatcg
     9361 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatcc actataaaat
     9421 catgatgcac ctgtcagata cttttaactc atgggactac cgtcaggttg agtattatta
     9481 ggatagagaa gaagtctagt gttaaggaca ttacagctca taatactagg cttttttata
     9541 gaaattcttt tctttttcta taggatatgg tattctatgt agaaaatata tgttaataag
     9601 taatgccaat atttaaacat cattagtaaa aggagttaga ttgatgaata aaagaaaagt
     9661 tagtttagaa gatttttata aatggtatag tctaaataaa gaagagttat taaataaggc
     9721 aactgttggt gaaaagttta atgataaatt aaaagaagag tttctccagg aatggccttt
     9781 ggataggatt ttaacaatgt caatcgatga atatgtaata ggaaagggac agcaaaataa
     9841 gtctttatgc tacgctcttg agaagggaaa atacaaaaat ctatttcttg gaatttctgg
     9901 tggctcagct tcaaaatttg gtatttattg gaataaaaaa acaaacaaat ataaagatca
     9961 agctaataat gagatttcag agttggatca gcgattttca aaattaaaat cagatttgta
    10021 tgaaattatc aaagaaggta ttcgttttaa ctttgaaaat cctatttttg atatgaaaag
    10081 atcaacaaat gaatttattg gtcgttctgc tatggtgaca aaattacttt gtatctattc
    10141 tgagggagat cctttctttg gtgtaaatat taatagtcag aaagaatttt ggaaccactt
    10201 tgtttctcag acaaatcaag gtggacctta tctgcaaaat cataaaataa ttgaactggt
    10261 gtccaaaact tatcctgagt tggagccatc gaaattagga actatgcttt ttgagtattc
    10321 taagcttttt atggaaaata aggaagacaa tagtacaatg gattcatcaa acaattttcg
    10381 tcatcaatta actcaatctc tattaaagtc tccaaacctt atccttcgtg gtgctcctgg
    10441 cacaggaaag acttatcttg ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga
    10501 ccaaatcgga tttgtacaat ttcacccatc atatgattat acggattttg tagaaggttt
    10561 aagaccagta tcaaatgggg atggagctat tgagtttagg ctacaggacg gtatttttaa
    10621 agatttttgt cagaaagcaa aagaaaccca attgattgga ggacaagata attttgatga
    10681 ggcttgggat tcttacttag aatatataaa tgttgctgaa gaaaaagaat atataacaaa
    10741 aacatcttac ttatctgtta atagtagaca aaatttgtca gtaaattatg atagtggtgt
    10801 tccaggatgg tcactaccta gcaaatatgt ttacgagttg tataaagata aaaattataa
    10861 taagcaagaa tactacaaaa gtggtggaaa aactgtccta gaaacattga gaaagagatt
    10921 tggtttgaaa gactatgttt ccccaacaga aattgatact gataagaaat tcgtcttcat
    10981 catcgatgaa atcaatcgtg gggagatttc taagattttt ggcgaactct ttttctctat
    11041 cgaccctgac tatcgtggtg aaaaaggaag tgtttctacc caatatgcaa atctacacga
    11101 aactgatgaa aagttctata tccccgaaaa tgtttacatc atcggaacta tgaatgatat
    11161 tgatcgttca gtggatacct ttgattttgc tatgcgtcgt cgttttcgtt ttgttgaagt
    11221 tactgccgag ggtcaagttg gcatgttgga taaagagctg aatatccatg cagaagaagc
    11281 aaaaattcgt ctaagaaact tgaacgctgc tatcgaaaat gttcaggaat taaacagtca
    11341 ttatcatatt ggaccaagtt attttcttaa gttgaaggat gtagattttg actatgaatt
    11401 actctggtct gattatatta agcctctcct agaagactac ttgcgaggtt cttatgatga
    11461 ggttgaaact ttggaaactt tgaaaaaagc atttgaactg acaaataatg agcaaaaaga
    11521 tcaggcagta gctgatgaca atgaaggcga tgaaaacgat gatgcggatt actgataatc
    11581 aacacaagat tattaaagaa aaatttgttg aagaatatcc taaactaagc aatcttcttt
    11641 tagacagaac cttggaaagt ctatcccaag atgaacgtat tttcattttt ccaaatgatt
    11701 tgactcatac tcctgatttg gataaggacc aaaagatttt tgaaacagtc aatcagaaaa
    11761 tcaagacagg gaacgtgatt ggttttcttg gatatggtca ggaaagatta acgatttcct
    11821 cacgattttc tgatgagagt aatgaccatt ttttgcatta tctcttaaac aaggttcttc
    11881 atatcaatct cactagttta gatgttgctt tgtctcgtga agagaggctt tatcaacttt
    11941 tgatgtatct cttccccaag tatctacaag ctgctattcg aaaaggtctt tataaggaat
    12001 accagagatt ttctcataac gacagtcatg ttaagggagt gattgatgta agaaaccatc
    12061 tcaagaaaaa tcttcctttc acgggaaata ttgcctacac aacgagagag ttcacctatg
    12121 ataatcccct catgcagttg gtccgtcaca ctattgaata cattaagaat cagaaaagca
    12181 ttggtcaagg ggtactagat aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc
    12241 gtgtaacgcc ctcttataaa ctagctgatc gtgctaagat tactcggaga aatcaatcta
    12301 aacctatacg tcatgcatac tttcacgagt acagaaactt acaagaactt tgtctgatga
    12361 tcctaaacca agaaaagcac ggtttagggt atcaagatca aaaaatctat ggtattctct
    12421 ttgatgttgc ctggctttgg gaagagtatg tttacacctt gttgccaaaa ggttttgtac
    12481 atcccagaaa taaggataag acggatggaa tttcagtatt ttctgttggg aaacgaaaag
    12541 tatatccaga tttttatgac agagaacgaa agattgttct agatgcaaaa tataaaaaac
    12601 tggaattgac tgaaaaagga atcaaccgtg aggacttatt ccagctgatt tcctattctt
    12661 atattttaaa agctgagaag gctggacttg tttttccgag caaggacaag gttattgata
    12721 atgagatggg aaacctagca ggttatggag ctcaattgaa gaagtggtct attcgaatcc
    12781 ctcagaatgc ctcattctat agtgcatttt gtaaaatgat ggaaaattca gaagaaaatt
    12841 ttaaagcgat tattgatgaa gaagtgggga gaaaataatt tcccctcttt cttttatttt
    12901 taacacaagc aaaacccgaa caatatattt taattcataa aataatttga caaaaactgt
    12961 actttagttt ataataaatt aaggaaaagg cgtagtgatg cgagagcata ggtaggtcat
    13021 tacaaaagaa acgagacatc gatatgttaa atgaatttcc aatttttgat tacgaagata
    13081 ttcaattgat tccaaataaa tgtgtcatta aaagccgtgc agaagcggat acaagtgtca
    13141 ctttaggaaa tcacaccttt aaactacctg ttgtgccagc gaatatgcag acgattttgg
    13201 atgaaaatgt agcagagcaa ctggctaaag gtggttactt ctacattatg caccgttttg
    13261 atgaggcagg acgcattcct tttattaaac gcatgcacga tcaaggactc attgcttcta
    13321 tctctgtcgg tgttaaggac tatgagtatg attttgttag ccagctcaag gctgatgctc
    13381 ctgagtatat cactattgat attgctcatg gtcatgcgga tagcgtgatt tctatgattc
    13441 aacacatcaa gaaagaattg ccagatacct ttgtcattgc tggaaatgtg ggaacaccag
    13501 aagctgtgcg tgaattggaa aatgctggtg cggatgctac taaggtcgga atcggtcctg
    13561 gtaaggtttg tatcaccaag gttaagactg gttttggtac aggtggttgg cagttggctg
    13621 ctctacgctg gtgtgccaag gctgcgcgta aaccgattat cgctgatgga ggaattcgta
    13681 ctcacggtga tattgccaag tctatccgct tcggtgctag catgatcatg attggttccc
    13741 tctttgcagg acacattgaa agtccaggga aaacgattga agtcgatggt gaacagttca
    13801 aagaatatta tggttcagcc tcacaatatc aaaaaggtgc ttacaaaaat gtggaaggca
    13861 aacgtatctt gcttcctgct aaaggtcatc tgcaagacac tttaactgag atggaacaag
    13921 accttcaaag tgctatttct tatgcaggtg gacgtcaggt tgctgacctt aaacacgttg
    13981 attatgtgat cgtgaaaaac tccatctgga atggggatgc ttcccactaa gacggggtct
    14041 ttgaccaaaa aacttgttat tagagcaaat ttctgttata ataaaacaag tttccaccct
    14101 tagtgtaatg gatatcacgt aagattccgg ttcttgagat gggggttcga ttccctcagg
    14161 gtggatgtaa acatcctaaa aagcctttaa tagggctttt ttctttatcc tgacccaaat
    14221 ttgccgctaa aactgagaat ctctgtctaa agaattccca aatgctttcc agtcccgttt
    14281 tagagtgact cagggggctt tttttgatat aataaaaagg actattatca gttagaaaga
    14341 agttggtatg aaagaattac aaactgtact aaagaatcat tttgaaatcg aatttgcaga
    14401 caaaaagtta ctggaaactg cctttactca tacgagttat gccaatgagc accgcctctt
    14461 aaaaatttca cacaatgaac gcttggaatt tttaggagac gctgttctac agttattgat
    14521 ttcagaatat ctatataaaa aatatcctaa aaagcctgaa ggtgacctat caaaactccg
    14581 tgctatgatt gtccgtgagg agagtttagc tggttttgcg cgtgattgcc agtttgacca
    14641 gtttatcaag ttgggtaaag gggaagaaaa atctggtggt cgcaatcgtg acaccattct
    14701 tggtgatgcc tttgaagcct ttcttggtgc ccttcttttg gataaggatg tggcaaaggt
    14761 caaggaattt atctaccaag ttatgattcc taaggtagaa gcaggcgaat ttgagatgat
    14821 tacagactat aaaacccatc tccaagagtt gcttcaggtc aatggtgatg tggctattcg
    14881 ttatcaggtg atttctgaaa cagggcctgc tcacgataag gtctttgatg tagaagttct
    14941 tgttgaaggt aagagcatcg gtcaaggcca aggtcgttct aagaaattag cagagcagga
    15001 agctgccaaa aatgccgttg agaaagggct ggattcatgt atttaaagga aatcgaaatt
    15061 caggggttca agtcttttgc tgataagacc aaggtcgttt ttgaccaagg tgtgacggca
    15121 gttgttggac ccaatggatc tggaaagtcc aatattacag aaagtctgcg ttgggctttg
    15181 ggggagtcta gtgtcaagag tctccgtggg ggcaagatgc cggatgtcat ctttgctgga
    15241 acagaaagtc gcaaaccgct caattatgct tctgtagttg tgactctgga taatcatgac
    15301 ggatttatca aggatgcagg tcaagaaatc agggtggaac gccatatcta tcgtagtgga
    15361 gatagcgaat acaagattga cggcaagaaa gtccgtctgc gtgatattca tgacctcttc
    15421 ttggatactg gattgggacg agattccttc tctattattt cccaagggaa ggttgaggag
    15481 atttttaatt ccaagcctga ggaacgacga gctatttttg aagaagctgc tggagtttta
    15541 aaatacaaga ctcgcagaaa agaaaccgag agtaaactgc agcaaactca ggataatctg
    15601 gaccgcttag aggacattat ctacgagttg gataatcaaa tcaagcctct tgagaagcaa
    15661 gctgagaatg cccgtaagtt tttagacttg gaaggacaac gtaaggctat ttatttagac
    15721 gttctggttg ctcaaatcaa ggaaaataag gcagaactag agtcgacaga agaagagttg
    15781 gctcaggttc aagaactctt gatgagttat taccaaaagc gtgaaaaatt agaagaagaa
    15841 aatcaaactc ttaaaaagca acgccaagat ttacaggctg aaatggccaa agaccaaggc
    15901 agtttgatgg acttgactag tctgattagt gatttagaaa gaaaattagc cctatcgaaa
    15961 ctggagtccg agcaagtggc cctgaatcaa caggaggcac aagctcgttt ggctgctttg
    16021 gaggataaga gaaattcact cagcaaagaa aagtatgata aagaaagctc tttagctctg
    16081 ttagagggaa atctagtcca aaataatcaa aaactcaatc gtttagaagc tgaattgctg
    16141 gctttctcag acgatcctga tcagatgatt gagctcttac gtgaacgctt tgtagctctt
    16201 ttacaagaag aagcggatgt ctcaaaccag ttgacccgta ttgagaatga gttggaaaat
    16261 agtcgtcagc tttctcaaaa acaagcagat caactagaaa agctgaaaga gcaattagct
    16321 acagctaaag agaaggctag tcagcaaaaa gacgagcttg aaactgccaa ggtgcaggtt
    16381 cagaaattat tggctgacta tcaagctatt gccaaggagc aagaggagca gaaaacttcc
    16441 tatcaagctc aacaaagtca actctttgac cgtctggata gtctcaaaaa caagcaggcc
    16501 agagctcaaa gtttggaaaa tatcctgaga aatcatagta acttttatgc aggtgttaag
    16561 agtgttctcc aagaaaaaga tcgcctaggt gggattattg gtgcagtcag tgagcatctg
    16621 acctttgatg tttattatca aactgcccta gagattgcct taggggcaag tagccagcat
    16681 atcatcgtag aagatgaaga gtcggcaacc aaagctattg atttcctcaa acgaaacaga
    16741 gtcggtcgtg caacctttct tcctttgacc actattaagg cgcgtacgat ttctagtcag
    16801 aaccaagatg ctatcgctgt aagcccaggt ttccttggga tggcagatga gttggtgact
    16861 tttgatacta gactggaagc cattttcaag aacttgctag ctacgacggc tatctttgat
    16921 accgtagaac atgcgcgtga agctgctcga caagttcgtt atcaggttcg tatggtgaca
    16981 ttggatggga cagaattacg cacgggtggt tcctatgcgg gtggtgccaa tcgccaaaat
    17041 aacagtattt tcatcaagcc agaactggag caattacaaa aagaaattgc tgcagatgaa
    17101 gcaagcttgg gttcagaaga agcggctttg aagaccttgc aagaccagat ggctgcattg
    17161 acagaaagat tagaagccat caaatctcaa ggagagcagg cacgtattca ggagcaaggc
    17221 ttgtccctcg cttatcagca aactagtcag caagttgaag aactggaaac tctttggaaa
    17281 ctccaagaag aggaaataga tcgtctttct gagggagatt ggcaagcgga taaggaaaaa
    17341 tgtcaagaga gccttgctac tatcgccagt gaaaagcaaa atctggaagc tgagattgaa
    17401 gaaattaagt ctaataaaaa cgccatccaa gaacgctatc aaaatttgca ggaagaggtg
    17461 gcgcaagctc gcttgcttaa gacagaactg caagggcaaa aacgttatga agtagctgat
    17521 attgagcgtt taggcaagga attggacaat cttaatatcg aacaagaaga aattcagcgc
    17581 atgctccaag aaaaagttga caatcttgag aaggttgata cagaattgct cagtcaacag
    17641 gcggaagaat ccaaaactca gaaaacaaat ctccaacaag gtttgattcg caagcagttt
    17701 gagttggatg atatagaagg tcaactggat gatattgcca gtcacttgga tcaagctcgc
    17761 cagcagaatg aggagtggat tcgcaagcaa acacgtgctg aagccaagaa agaaaaggtc
    17821 agcgagcgct tgcgccatct acaaaatcaa ttaacagacc agtaccagat tagctatact
    17881 gaagcactag aaaaggcaca tgaattggaa aacctcaatc tggcagagca agaggtgcag
    17941 gatttagaga aggctattcg ctcattggga cctgtcaact tggaagctat tgaccagtac
    18001 gaagaagttc acaaccgtct ggactttcta aatagtcagc gagatgatat tttgtcagcg
    18061 aaaaatctgc tccttgaaac cattacagag atgaatgatg aggtcaagga acgctttaaa
    18121 tcaacctttg aagctattcg tgagtccttt aaagtgacct tcaagcagat gtttggcgga
    18181 ggtcaggcag acttgatatt gactgagggc gaccttttaa cagctggtgt ggagatttct
    18241 gttcaacctc caggtaagaa aatccagtcg cttaacctca tgagtggtgg tgaaaaagct
    18301 ctatcggctc ttgccttgct tttctccatt attcgtgtca agaccattcc ttttgtcatc
    18361 ttggatgagg tggaagctgc gctggatgaa gccaatgtta aacgttttgg ggattacctc
    18421 aaccgttttg acaaggacag ccagtttatc gttgtaaccc accgtaaggg aaccatggca
    18481 gcggctgatt ccatctatgg agtgaccatg caagaatcgg gtgtttcaaa gattgtttca
    18541 gttaagttaa aagatttaga aagtattgaa ggatgacaat taaactagta gcaacggata
    18601 tggacggaac cttcctagat gggaatggac gctttgatat ggatcgtctc aagtctctct
    18661 tggcttccta caaggaaaaa gggatttact ttgcggtggc ttcgggtcgg ggatttctgt
    18721 ctctggaaaa attatttgct gatgttcgtg atgacattat tttcatcgcg gaaaatggca
    18781 gtttggtaga gtatcaaggt caggacttgt atgaagcgac tatgtctcgt gacttttatc
    18841 tggcaacttt tgaaaagctg aaaacgtcac cttatgtaga tatcaataaa ctgctcttga
    18901 cgggtaagaa gggttcatat gttctagata cggttgatga gacctatttg aaagtgagtc
    18961 agcattataa tgaaaatatc caaaaagtag cgagtttgga agatatcaca gatgacattt
    19021 tcaaatttac aaccaacttc acagaagaaa cgctagaagc tggtgaagct tgggttaatg
    19081 aacatgtccc tggtgttaag gccatgacaa ctggctttga atctattgat attgttctgg
    19141 actatgtcga taagggtgta gctattgttg aattagctaa aaaacttggt atcacaatgg
    19201 atcaggtcat ggcttttgga gacaatctta atgacttaca tatgatgcag gttgtgggac
    19261 atcctgtagc tcctgaaaat gcacgacctg aaattttaga attagcaaag actgtgattg
    19321 gtcaccataa ggaacggtcg gttatagctt atatggaggg cttataatgg cagatataaa
    19381 attgattgca ttggacttgg acgggacctt gctgactact gataaaaggc tgacggatcg
    19441 taccaaggaa accttgaaag ctgcgcgtga tcgtggtatc aaggtcgtat tgacaactgg
    19501 tcgtcccata aaagccatgg atttctttct ccatgagtta gggactgacg gtcaggaaga
    19561 tgagtatacc attactttta atggtggatt agttcagaaa aatacaggag aaatccttga
    19621 taaaacagtc ttttcatatg atgatgtggc acgtttgtat gaagaaacag agaaattatc
    19681 actgcctctt gatgccatct cagaaggaac agtttatcaa atccaatcgg accaagaaag
    19741 tctttatgcc aaattcaatc cagctttgac ctttgttcca gtggactttg aagacttatc
    19801 tagtcaaatg acctacaaca aatgcgtgac tgcctttgct caagaaccct tggatgcagc
    19861 cattcagaag atttctccag aattgtttga ccaatatgaa atctttaaat cacgtgaaat
    19921 gttgctagaa tggtcaccaa agaatgttca taaagcaaca ggtttggcaa aactaatcag
    19981 ccatcttgga atcgaccaaa gtcaagtgat ggcttgtggt gacgaggcca atgacctctc
    20041 tatgattgaa tgggcaggtc ttggtgttgc tatgcaaaac gctgttcctg aagtaaaggc
    20101 agccgcaaat gtagtgacgc cgatgaccaa cgatgaggaa gctgtcgcct gggctatcga
    20161 agaatatgtg ctaaaggaga actaagatat gggattgttt gaccgtctat tcggaaaaaa
    20221 agaagaacct aaaatcgaag aagttgtaaa agaagctctg gaaaatcttg atttgtctga
    20281 agatgttgat cctaccttca cagaagttga ggaagtttct caggaagaag cagaggttga
    20341 aattgttgaa caagctgtgt tccaagaaga ggaaatccaa gacacagttg aagaaagtct
    20401 ggatttagag ccagttgtag aagtttctca aaaagaagtc gaagaatttc cacactcaga
    20461 agaagggaat actgagtttc tagagactat agaagaaaat aattctgaag ttcttgaacc
    20521 agaaaggcct caagcagaag aaaccgttca ggaaaaatat gaccgcagtc ttaagaaaac
    20581 tcgtacaggt ttcggtgccc gcttgaatgc cttctttgct aacttccgct ctgttgacga
    20641 agaatttttc gaggaactgg aagaactgct gattatgagt gatgttggtg tccaagtcgc
    20701 ttctaactta acggaggaac tacgttacga agccaagctt gaaaatgcca agaaacctga
    20761 tgcacttcgt cgtgtcatca ttgagaaatt ggttgagctt tatgaaaagg atggtagcta
    20821 cgatgaaagc atccacttcc aagataactt gacagttatg ctctttgttg gtgtgaatgg
    20881 tgttgggaaa acaacttcta tcggaaaact agcccaccgc tacaaacaag ctggtaagaa
    20941 ggtcatgctg gttgcagcag ataccttccg tgcgggtgca gtagctcagc tagctgaatg
    21001 gggccgacga gtagatgttc cagtagtaac tggacctgaa aaagctgatc cagccagcgt
    21061 ggtctttgat ggtatggaac gtgccgtggc tgaaggtatc gatattctca tgattgatac
    21121 tgctggtcgt ctgcaaaata aggataacct tatggctgag ttggaaaaga ttggtcgtat
    21181 tatcaaacgt gttgtgccag aagcaccaca tgaaaccttc ttggcacttg atgcatcaac
    21241 aggtcaaaat gccctagtac aggccaaaga attttcgaaa atcacacctt taacgggaat
    21301 tgttttgact aagattgatg gaactgctcg aggaggtgtg gttctagcca ttcgtgaaga
    21361 actcaatatt cctgtaaaat tgattggttt tggtgaaaaa atcgatgata ttggagagtt
    21421 taactcagaa aactttatga aaggtctctt ggaaggttta atctaatcag aagcaaaaat
    21481 cctgcaaggc ataaacttgc aggaaatttt tttattctaa gcgaccatct tgacgatagg
    21541 tgatatctgg ttgccaagtc catttggcac cgaatttttc aagtaggtca aagctggctt
    21601 gaggtcccat gcttccagct ttatagtcat gaagtggggc accattttca gcccagagct
    21661 tttcaatacg gtcaatcaac ttccatgacg cacaaacttc atcccagtgg ctaaagttag
    21721 ttgagttgtt atttaggaca tcataaatca atttttcgta tggttctgga gaagcaccag
    21781 ttgcagtcgc atctgtacgg taatcaagtg agttaggagc caagttaaat tcttctccta
    21841 cttgcttccc atttaggcta agagagaagc cttctgttgg ttgaatatag atggtcaaaa
    21901 tatttggagc aagtggttct ccaaagatag aatccatttg tttaaagacg atgttgacat
    21961 gagttccttt ttcagtcagt cgtttacctg tacggaaaaa gaaaggaaca ccacggaatc
    22021 gatcgctgtc tacaaagaag gcaccagatg taaaggtttc agttgttgat tctggattca
    22081 catttggctc gctacgataa gagatgtatt tcatgccatc aatcttacca gagcggtatt
    22141 gcccacggat aaagtgttct ttgagttctt catcagttgg atgatagagg tttttaaaga
    22201 ccttaatctt ttcagcacga atctcgtctt ttgtgaagct tgctggtttg tccatggcga
    22261 ggagcgaaag aagttgtaga gtgtggtttt ggaccatgtc acggagggca ccggattggt
    22321 catagtagcc accacgttct tctacaccca agcgctccgc aaaggtaatt tgaacattgt
    22381 cgataaaatc cttgttccaa acgttttcaa aaatcaagtt tgcaaagcga actgcaaaga
    22441 tgctttggat catttcctta ccaagataat ggtcgatacg gaaaatttgt tcttcgtcaa
    22501 atgttgctag gagttcgtca ttcaacttgt ttgcagttgc gtaatctgta ccaaatggtt
    22561 tttcaacgat caagcgctca aaacctttgc catcgacaat gttttcagat ttgaggtgtt
    22621 tggcaatggt tccaaagaac tgaggtgcca tagacaagaa gaagagctta ttgtgttcag
    22681 cttggtattt ttcattaagc tcagcttgta attgacgcaa agcaatataa tgttccgaat
    22741 cattgacatc atggctttga tagtagaagt ggctagcaaa ttcttgggct tgctcggtac
    22801 tatctgccaa atcaaggatg gactcgacaa ctacagattc aaaatattcc ttactccaag
    22861 gtctacgggc agttccaata acggcaaagt gcttggaaag attgccggat ttatatagtc
    22921 taaaaaggga agggtagagc ttgcgtttag ccaggtctcc actcgcaccg aaaattgtaa
    22981 caataacctt agatgacatc tagctaccta atttctattt ttattcctag tcttgctagg
    23041 tatgaggaaa cctcatttca taaacttaat tctaacataa ttttccgaaa aatcaaaaat
    23101 tccaatacga ggtagaaaaa ctgcaaggaa atccttacag tttgagttta gacgtttaag
    23161 accttatcta agaactcttt cagacgaggg tgttgtgggt tatcaaagat ttggtcaggt
    23221 gttccgtctt caaggaactc gccatctgca gtaaagataa cgcggttggc aacctgacga
    23281 gcaaatccca tctcatgggt tacgataatc atggtcatgc cttgctcagc caattccttc
    23341 ataacgttaa gtacgtctcc aaccatctca gggtcaaggg cagaagttgg ttcatcgaag
    23401 agcatgatgt ctggattcat tgctaggcca cgagctatgg ccacacgttg tttttgacca
    23461 cctgataggc tatctggatt ggcattagct ttatctgcta gtccaacctt ttcaagcaac
    23521 tccattccca atttctcagc ttcttcctta gtcatcaact tgtgctcaat aggagcaaag
    23581 gtgatgttgt ccaatacaga catatgaggg aagaggttga agtgttggaa taccatgccg
    23641 atattttcac ggacgtggtc aacattggtt gttttttcag ttaaatcata gccgttcaca
    23701 gtgatgtgac cgctagtgac ttcttctaaa agattgaggc tacggaggaa agttgactta
    23761 ccagaacctg aaggaccgat gatacaaaca acatctcctt catagaactt agtcgtaatt
    23821 ccttttagga cttcattttt tccatagtgc ttgtgtaaat catttacatc aatttttaat
    23881 tttgccatta acgaatcctc ttttctaagc gtttcgctag tctagtcaaa agtgtgataa
    23941 ttacaagata gaagatagca aggattgcat acatcttgaa actttggtag ttacgagcaa
    24001 tgataatctt accagtttgg aagagttcaa ccaaaccgat agcagatacg atagttgtat
    24061 ctttaagagc gataacgaat tggttgacaa agtttggcaa catcaattta gttgcttgtg
    24121 gcaagataat cttacgcatg gtttttccat aagagatacc caagcttcgg ctggcttcca
    24181 tttggccaac tggaacggcc tgaataccac cacgaacgat ttcagcgata taagcagccg
    24241 cattgagtga gagggcaatg gttccagcta caaagtcgtt aattgggctt tgttggcctg
    24301 tgatagactc gatgaagttt ggaattcccc agaagatgaa ggctgcaaga atcatcaatg
    24361 gaataccacg aataacgtca acgaaaatct cagagatgac gcgaagagat ttgtatgggc
    24421 taacgctaaa cataccgaag ataattccga tgacaatggc aatagcaaat gagataagag
    24481 ctagagcaag agtgatacca agaccgctaa ggagttgttt gtagttgttt tgaagcaagc
    24541 cccagagcgt tgtttcgtca acagtacttg ttgaagcagt tgaagattcg ctagctaggt
    24601 atttgtcaag aatcttttgg aattcaccgt ttgctttaag gtttgcaagt ccgttgttga
    24661 acatttcaat cagttctgga tttgctcctt ttttaacggc aaaggctgtt tcaccgattg
    24721 gagttccaga gattggagtt ttcaattttt gaccttggct gatagaatat ttgagaacag
    24781 gttcatcatc cataacggca tcaatggcac cagtgtttaa actgtcatac attgaagaac
    24841 catcagcaaa ggttttgatt ttgtagccgt atttgctttg attttctgtt aggaaggttt
    24901 gagaagcagt tccgttttta acaccgactg tctttccttt tagatcttca taagaagcaa
    24961 tattacttga ttctttgaca ccaagaatgg tattagcagt gtagtatgat tctgagaagt
    25021 caaaagttgc cttacgagca tctgtgacag acataccagc gatgatacca tcggcttgac
    25081 cagcttggac agcactgata gcagcatcaa aaccagggtt ggtgatttca atttcaaaac
    25141 cttggtcttt agcgattgcc ttaatcaatt ccatatcaat accagtgtat tggttgcttg
    25201 aattttggaa aacaaaaggg gcaaaagaag aatcgctggc aatgatatat ttagccttaa
    25261 caggaatagc ttttaatcct gcgagagtag ttgtagttgg cactgctgaa gatgatgaag
    25321 cagtccattt cttgataatt ttatcaagac taccatcttt tttcatttca gacaaggctt
    25381 ggttaaattc agtaaccagg tgctcgtatt tacttccttt tttcacaccg aaagcaaaac
    25441 ttcctacagc ttcaccatcc atttcaatat ggaggtcttg accttggtta atggcatatt
    25501 cgataacagg tttgtcatcc atcatggcat cgatggcacc agcactcaag ctgttgttca
    25561 ttaaatcacc agtgtcaaat gttttaatag taaagccata tttatctttg attgtttcaa
    25621 ggaaacgttg agcggcagtt ccgtttttaa caccaacggt tttgccagtt aattggtcgt
    25681 acttgctaat tttgtgtgac tttgtagtag caatgacaac ttttgtatca tagtaagtat
    25741 cagacatggt gaagactttt tcacgttctt tagtctttgt catccctgcc atgatagcgt
    25801 cggcttgccc agcttgaacc gcattgactg ctgcgtcaaa tccaggatag gacatctgaa
    25861 tgttccagcc tttaatctca gcgactttgt taataatgtc aacatcaatt cctttataag
    25921 tttgatctga atctttaaac tcaaaaggtg cataggcggt atcagaaaca atcttaatcg
    25981 tttctgcttt ggcaatacct aatgagaaaa ttgggaataa aattagcaaa aatgctagaa
    26041 attttttctt catttttagt ctccttttcc gaatattctc tcattatatc agaaaaagta
    26101 aaaaaaggca aattgttata tttttcgtgt cagaaaatat aacattgatt tttccttttc
    26161 tttcttgaat tgctattaaa aagtgctata ataatagtat atatagaaga aaagaggacg
    26221 gggatatgaa gaacaaaaga atatttaaag acttccaagc ttcaaaaatg agtttaaaca
    26281 tttacacaag ccccttgtta gcctttgttt ttgtcttcat aggagagttt gtggctttta
    26341 ctttgtatgg tattggcttg ttagctctca tcggacttgc tagaaatttt ggagaggctg
    26401 gtcaaaatct tgcaacctac ttgcagacct tgcatcagag cttgacggat aaaacaagtg
    26461 actttcgttt aattttagga ttactggcct ttggttttat tcttaacact gtgttcagat
    26521 ggacaagaaa agttgagaaa agacctattc gaaccttggg attttataga gagaatttcc
    26581 tcagcaatct tctgaaagga tttagtctag gcttggcact ttttcttctg accttgttag
    26641 gtttagtggt cttaggtcaa tatcgtttgg aatccattca cttgaatcct tattctcttg
    26701 cctttgtcgt ctttactatc ccattttgga ttttacaggg gacagcagaa gaagtggtgg
    26761 cccgtgcttg gctacttcct caattggcct caagaaccaa tctaaaacta gctattctta
    26821 tatctagcct gttctttacc ctgcttcata tgggcaattc tggcctcacc cctctatctc
    26881 tagtaaatct ctttttattc ggagttgcca tggctcttta tcttctcaaa actgatacag
    26941 tttggggtgt tgcaggtatt catggtgctt ggaattttgc tcagggtaat ctctttggga
    27001 ttttagttag tggtcaaccg tcaggaacgt ctctgatgac ctttttacca caaggcaatc
    27061 aagattggct atcaggtggt tcttttggca tagaaggttc cattatgaca agtctggtat
    27121 tactactgct gattgtctat cttgctaata aattaaagaa agaaaatgaa aggatgtgac
    27181 ttcggtccgt ccttttcttc gtgaaaatac tataagtatg ctaaaatagg aatagcacat
    27241 ggagagagga ttcttatgat caatcacatt acagataatc aatttaaact agtatcaaaa
    27301 tatcaaccat caggagatca accccaagct atcgagcagt tggtggataa cattgagggg
    27361 ggagaaaaag ctcagattct gatgggggcg actggaacag ggaagaccta tactatgagt
    27421 caggtcattt ctaaagtcaa taaaccaact ctggttattg cccacaataa aactctggct
    27481 ggtcagctct atggggagtt taaggaattt ttccctgaaa atgcagttga gtatttcgta
    27541 tcctactatg attattacca gccagaggcc tatgtccctt ctagcgatac ctatattgag
    27601 aaggatagtt ctgtcaatga cgagattgac aagcttcgcc actcagctac ctcagccctt
    27661 ttggagcgta atgatgttat tgtcgtggcc tcagtctctt gtatctatgg tttgggttcg
    27721 cccaaggaat acgctgatag tgtcgttagt ctccgtcctg gtctagagat ttctcgtgat
    27781 aaactcttga atgacttggt cgatattcag tttgaacgta atgatattga tttccaacgc
    27841 ggaagatttc gcgttcgtgg ggatgtggta gagattttcc cagcttcccg agatgaacat
    27901 gcctttcgag tagaattttt tggagacgaa attgaccgta tccgtgaggt tgaggctctg
    27961 acaggtcagg tattgggaga ggtggatcat ttggcgattt tcccagctac tcactttgtg
    28021 accaatgacg accatatgga agttgccgtt gctaagattc aagcagaatt agaagagcag
    28081 ttagctgtct ttgagaagga aggtaaattg cttgaagccc agcgcttgaa acaacggaca
    28141 gagtacgata tcgaaatgct gcgcgagatg ggctatacaa atggggttga aaattattct
    28201 cgccacatgg atggacgtag tgaaggtgag cctccttata cgcttctcga ctttttccca
    28261 gatgattttt tgattatgat tgacgagagt catatgacta tgggacaaat aaaaggcatg
    28321 tacaatggag accgttcgcg taaggaaatg ctagtaaatt atggtttccg tttaccgtct
    28381 gccttggaca atcgtcctct ccgtcgtgag gagtttgaaa gccatgtgca tcagattgtt
    28441 tacgtatcag cgacacctgg tgactatgaa aatgaacaga ctgagacggt gattgagcaa
    28501 atcattcgac cgacagggct tttggatcct gaggtggaag tccgtccgac tatgggacag
    28561 attgatgatc tcttaggtga aatcaatgcc cgtgttgaaa agaatgaacg aacctttatc
    28621 accaccttga ccaagaaaat ggcagaggac ttgaccgact atttcaagga aatgggcatc
    28681 aaggtcaagt acatgcactc ggatatcaag accttggaac ggacggagat tatccgtgat
    28741 ctccgcttgg gtgtctttga tgtcttggtt ggaatcaatc tccttcgtga agggattgac
    28801 gttcctgagg ttagcttggt tgccattctc gatgctgaca aggaaggttt ccttcgtaac
    28861 gagcgtggac tcatccagac cattgggcgt gccgcccgta acagtgaagg tcatgtcatc
    28921 atgtatgcag atacggttac ccagtctatg caacgtgcta tcgatgaaac tgcccgccgt
    28981 cggaaaattc agatggccta taatgaagag catggtatcg taccacagac aatcaagaaa
    29041 gaaatccgtg acctgattgc cgtgaccaag gcagttgcta aggaagagga caaggaagtc
    29101 gacatcaata gcctcaacaa acaagagcgc aaagaactcg tcaagaaact agaaaaacaa
    29161 atgcaagaag ccgtcgaagt gcttgacttt gaactggcgg ctcagatccg tgatatgatg
    29221 ttggaagtca aggccttgga ttaggggaat agtatgattt atttaagaaa gttaaagaaa
    29281 gaagatttga tgtctttatg ggaaatggct tattcacagc ttaatccagt ttggaaacag
    29341 tatgatgctc cctattatga tgattatcag tatttttcaa attttaaaga attcgaacta
    29401 caaaaatcag aatccatttt aagcaactca aatcgccttg gtatttttgt tgatgataaa
    29461 ctagttggga ctgtttcgcg ttattgggta tgtaaagaaa caagatggat ggaattggga
    29521 attggtattt atgataaaaa attctggaac actggtattg ggaaagttgc tatgttgcag
    29581 tggatagata ggacgtttca ggattacttg gagttggagc atctgggttt gacaacttgg
    29641 tcaggaaatc ttggtatgat gaaacttgct gaaaaattaa gaatgaaaaa agaagctcat
    29701 attccaaaag ttcgttatta tcaaggtaaa tattttgata gtattaaata tggtattttg
    29761 agagaagact gggagaaaat aaatgacggt tattatcaaa tcaatggaaa ctcctgaaga
    29821 gatagaaggt aaatccctcg ttcactggca aacgtggaga gaggcttatg atgacctttt
    29881 gcctgcagaa tttcaggaga caatgacatt agaaagatgt cgattcttta gtcaaaagta
    29941 tccagaaaat acattgattg cgataggtga tctgaaggta gttggtttta tcagttatgg
    30001 taactttcgt gatgagacta ttcaagctgg tgaaattatt gctttatatg ttttaaaaga
    30061 ctattatgga aaaggtatcg cacaaaagtt aatgaaagca gctttgactg ctcttaatca
    30121 tttttctgaa attttcttat gggtattgaa agataacaag cgcgccattg ctttctatca
    30181 aaaaatgggt tttacttttg atggacaaga aaaaatactt gaacttggaa agcctataaa
    30241 ggaaaaacga atggtgttct attctaaata attttaaaaa agtaaaagat aatatctctg
    30301 gtagtaagtc tgaaaattta ataaattaga aagcgagtaa atttatgttc cgttcccaat
    30361 taacaatttt aacaaatatc tgtctgattg aagacctcga aactcagcgc gtggtgatgc
    30421 agtatcgcgc ccctgaaaac aatcgctggt ctggttatgc ctttcctgga ggtcatgtag
    30481 aaaatgatga ggcttttgcg gagtctgtca ttcgtgaaat ctacgaagaa acagggttga
    30541 ctatccaaaa tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct
    30601 atattgtcat ttgttataag gcgactgagt tctctggtac ccttcaatct tcagaagagg
    30661 gagaagtttc ttgggtgcaa aaagaccaga ttccaaactt aaatctggcc tatgatatgc
    30721 taccattgat ggaaatgatg gaagctcccg acaagtcaga gtttttctat cctcgccgta
    30781 cagaagacga ttgggaaaag aaaatcttct agtcttttac taaataacct agctgatcca
    30841 aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga
    30901 tgccatctgt caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat
    30961 gttgcacatc tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat
    31021 ggtcaatcaa ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac
    31081 cgatttcttc aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa
    31141 tttgcttata gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa
    31201 ttgcaatgtc ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc
    31261 cattaagggc tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg
    31321 tcatagcttt tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt
    31381 atagtctacc atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa
    31441 catgttttct acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc
    31501 aagggcatga acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag
    31561 ggtatcgggg aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa
    31621 agcccgaaaa acgataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag
    31681 gatgacaaaa actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct
    31741 ccccaaagta taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa
    31801 aatcgcaata gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt
    31861 cacaagaatc tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa
    31921 agcaagaatt tacttgggtt tatagatcat tttttagtta aaagttatag tagatggaaa
    31981 ctagaatagt ccacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
    32041 gatttgtcct gttcttattt cgttttacta tagtaaagat ttcattaaaa agaaactgta
    32101 tagagcaaaa tctccacctt caggtttgaa agcggagatt gtttttattt tttcaaggtt
    32161 tgtagtcgtg gaacaatggc tagggttaga attgcagaaa tgaccaattc agcaattgaa
    32221 tttgttgaga taacggttgc cagaagaagt tggatatttc cattataaac atttccaaat
    32281 aggaagaaga ttcctccaag gacaaagata gtatttgtca aggaaccaag ggctccagct
    32341 aaaatcagac cagtcttgtt tttcatcagt ttatagacta agtaaggagt taaaccaatc
    32401 aaaatacgtg ggacgatggc aatgatagct gagtagatgt ttccgtttgg tacgaaggga
    32461 gagaagaggt agcttgtcgg tagaatcgta atcgtgttaa ccgtcaagct aagtaatccc
    32521 atcaaaaatc caagtgtaac cccaactcgt ggaccataaa taatgctggc aataatgaca
    32581 ggaatatgaa caatggtcgg tttgattgga aatggaaaaa ggttaaagat aagtgagctc
    32641 agaaagtgta tcacgagcat ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt
    32701 tttttcatcg atagtttcct ttattctttc taaaataatt gtgaggtcag ctaaagctcc
    32761 tcgtccgtgg tctccacaag ctagtaggga ttccttagga gcaatcagct gatagccgta
    32821 ggtttctaat gttttcagat tattctgagt tactggatgg tcatacattt ttgtattcat
    32881 agcaggagct attagtttgg gaatatgact tggtagggct agagctgtac tggttaccat
    32941 gttgtccgca aatccgtgag ctagttttgc aatagtgtta gcagttgcag gtaccacgat
    33001 aaataaatct gctttttttc caagttcgat atgattgacc tgatcaggat agggttcctt
    33061 catgacatcc aagtggacag gattctgtga gagtacctgt agtgtcaaag gttggataaa
    33121 ctctgtagca gcctgagtca ttaagacagt gacttgatgg ccttgttttt ttagagaact
    33181 gactaaatct gccgacttat aagaggcgat tgaacccgtt acagccaaga gaatgtttgc
    33241 catagttttc ctttctaaga atgataggct tgaatttttt caaggaggag ttctgcaatt
    33301 tcttctttag tctggactgt ttgaagctga tttttctcaa caaatatagc tcggtgctga
    33361 tctgctgaaa tttgagtcag gtcattcgcg atgattaaat ctgcttgatt cttgataaga
    33421 ctttttcgtg caatgtcaac cagatgatct tcggtaacat caaccagcag tttgaaacca
    33481 atcagatgaa tagtgggatt ccattccttg actagggata tgattttggg tgtcttttta
    33541 aggaacaaaa cctgaacctc atcagttgaa gaaatcttgg cctgatgatt ctgcttgctt
    33601 aaaaattctt ttagattgga gctagcctga acttcctcaa gccctgtcat ataaacagga
    33661 gtgtagtcag aaacagccat tgagtggatc aagacctgat aatcctgaac acgttcttgc
    33721 atttctatta gaaggtcctt ggtattggta acttctcgaa tacttaggtt aggatgaggc
    33781 tctggcttca gagctcgttt tgtcgtaatt aaacaaactt catgccctgc agaaagcaaa
    33841 gtctctgtga taattttccc caagtgacct gtagaatggt tagtgataga gcggacgcta
    33901 tcgatagctt cactggtacc gcccgatgta actaaaattt tcatagcact attgtacaca
    33961 aaaataagcg gtaagtaaaa tgaaagtgat aaatttttgg taaaaacgaa gatttactat
    34021 agtttcaaac tataaagcca tataaaattt aagaaaggat tctaaaagcc ttaaaaacag
    34081 agatatttac gaacgtttag agggttttag gatgttaaaa atcttgtttt gtgatataat
    34141 gaattatcat ataagaggtt agaggaattt tgaatgaaaa cagatattga aatcgcacag
    34201 agtattgagt tgaagccaat tgttgatgtt gtagagaaac ttggtatttc ttacgacgat
    34261 ttggagttgt acggaaagta caaggctaaa ctcagctttg ataaaattcg tgcagttgag
    34321 agcaatccag tcggtaaatt gatcttggtt actgccatca acccaacacc tgcaggtgaa
    34381 ggaaagtcga cgcttaccat tggtcttgcg gatgccttga acaagattgg caagaaaacc
    34441 atgattgcta tccgcgaacc gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct
    34501 ggtggtgggt atgcacaagt tctgccaatg gaagacatca acctccactt tactggagat
    34561 atgcatgcta ttacaactgc caacaatgcc ctttctgcct tgattgacaa ccacttgcac
    34621 caagggaatg agctgggaat tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg
    34681 aacgaccgtg cgctccgcca tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca
    34741 cgtgaggacg gttttgatat tacagttgct tcagaaatca tggcaattct ttgcttggca
    34801 acggacatcg aggacttgaa acgtcgtttg gcgaatatcg ttattggtta tcgctatgac
    34861 cgtacgcctg tttctgtagg tgatttgcag gttgagggtg ccttggcttt gattttgaag
    34921 gatgctatta agccaaactt ggttcagaca atttacggta cacctgcctt tgtacacggt
    34981 ggtccatttg ccaatattgc tcatggctgt aactctgttt tggcgacgac aacagccctt
    35041 cacttggctg attacactgt tactgaagct ggttttggtg cggaccttgg tgctgagaaa
    35101 ttccttgata tcaagacacc aaacttgcca acatctccag atgcagttgt tattgtcgca
    35161 acccttcgtg cccttaagat gaatggtggt gtggctaaag acgctctgac tgaagaaaat
    35221 gtagaggcag ttcgtgcagg ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag
    35281 ttcggtattc cagcagttgt agctattaac gaatttgtat ctgatacaga agctgaaatt
    35341 gcagtcttaa aagaactctg tgcctcaatc gatgtaccag ttgaattggc tagtgtctgg
    35401 gctgatggag cagaaggtgg agtagcactt gccgaaacag ttgttaagac aattgctgaa
    35461 aatccagcta actataaacg tttgtatgat aatgaccttt ctgtccaaga aaagattgaa
    35521 aaaattgtca ctgaaatcta tcgtggtagc aaagtgaact ttgagaagaa atctcaaaca
    35581 caaattgctc aaatcgttca aaacggttgg gacaaattgc caatctgtat ggctaaaact
    35641 caatacagtt tctcagacaa tccaaatgcg cttggagcac cagaaaactt tgaaattacc
    35701 attcgtgaat tggtaccaaa attaggtgca ggcttcatcg ttgccttaac tggtgatgtt
    35761 atgaccatgc caggtcttcc aaaacgtcca gcagctctca acatggatgt tgaaagcgat
    35821 ggaactgtac taggcttgtt ctagtggatt gaaattgact ttaagtgagt ttggaaataa
    35881 tatccaagct cattttttct cagactgcaa gcagttcatc aataagattt atactcttcg
    35941 aaaatctttt caaactacgt cagcttcacc ttgccgtagg taatatgata ctgactctgt
    36001 cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt
    36061 gctctttgat tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat
    36121 attataaatc agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga
    36181 tttgaaagaa cacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa
    36241 acttctcgct tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc
    36301 ttatcacatc tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc
    36361 ttactacgaa agatttttgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga
    36421 ggagagttta ctgaaagctt gggagggctt gggttattat tctcgagttc gcaatatgca
    36481 ggctgcagcc cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg
    36541 aatttccagc ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt
    36601 taacttgcct gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga
    36661 agtcaaccac gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat
    36721 cttgattaat ccagatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga
    36781 tattgagtct cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc
    36841 atatcagaat ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc
    36901 tatttatctt aaagccttag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa
    36961 tgaaagcgaa aagctcttgg caggtttttg gcatttcccc tttatagaag ttgataactt
    37021 ttcgcaagaa gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactttgg
    37081 ccccagtcca gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt
    37141 ttgttttgat acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc
    37201 aggtcaggtg agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga
    37261 agaattcaag aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca
    37321 agccaactta gacagtagcc aagactagct attgtgcctt ctgactattt tttggtataa
    37381 tagtagagaa aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat
    37441 ctcggatatt atcaagttta atatgaccaa ggaaggttat gaagttgtaa ctgcttttaa
    37501 tggtcgtgaa gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt
    37561 gatgcttcca gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt
    37621 gcccattctt atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact
    37681 tggggcagat gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa
    37741 agctcttctg cgtcgttctc aacctatgcc agtagatggt caggaagcag atagtaaacc
    37801 tcaacctatc caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata
    37861 tggcgaagaa ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca
    37921 tacaggtcaa gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt
    37981 tggtgatgtc cgtacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac
    38041 gcccagccga ccagagtata tcttgacacg ccgtggtgta gggtattaca tgagaaataa
    38101 tgcttgattt actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt
    38161 taggtttcat ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt
    38221 tgaagcaaat caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg
    38281 atatgcaagg tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg
    38341 ttattcgtct cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt
    38401 tttatatgac agatggggtt cttgcgacca accgtcgggg tcagattatc atgattaacg
    38461 atacagccaa gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg
    38521 aattgctcaa gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat
    38581 tgttgctaga ttcccaagat atcaatggtg aatatttgaa ccttcgagtt cgctttgcct
    38641 tgatacgtcg agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg
    38701 agcaggagaa ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac
    38761 ggactcctct gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg
    38821 aaactgtagc accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca
    38881 tggtgacgga tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg
    38941 aactgattaa cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag
    39001 gacaggaaaa ggagaaaaaa tatgagttgg tgagagatta tcccatcaat tctatctgga
    39061 tggaaattga tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta
    39121 agtattcgcc agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga
    39181 ttttatccat ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg
    39241 accgtttcta tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac
    39301 tgtctatcgc taaagaaatt attaaacaac ataagggctt tatttgggcc aagagtgaat
    39361 acggcaaggg ttcaaccttt accattgtgc tcccttatga taaggatgca gtgaaagaag
    39421 aagtatggga ggatgaagta gaagactaga atgagtaaaa taggctttaa atacagtatt
    39481 ttagcgtcgg gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta
    39541 gtggatgcag gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgcaag
    39601 ccagaagacc tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta
    39661 ggcgttttgg ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct
    39721 atggaaaata gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg
    39781 ggtaaaacca aaacttttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca
    39841 gtcgcaccgc agttctatcg ctttatgaag gatgacaaga gttttgtcct tttgacagat
    39901 acaggttatg tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ctatcttatc
    39961 gaggccaacc atgatgtaga gattttgcga tcaggttctt acgcttggcg actcaaacaa
    40021 cgaatcctat ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg
    40081 acgctaggaa atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc
    40141 aaggaactgg ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga
    40201 gtagacttta aggtttatga tacctcacca gataccgcaa caccattgac agagatatag
    40261 aaagaacgct gagaaggtgt tctttttata ttgactgaac acctaaaaag taatacaatg
    40321 gtgttaccat taaaaaaggg agcacaaaag atgactacta ttacattaaa agtttctgaa
    40381 gctgataaaa catttatgaa agcaatggct aagtttgaag gagtttccct ttcggaactt
    40441 attcgcacca aaactcttga agccctagaa gatgaatacg atgctcgtgt ggcagattta
    40501 gcctatcaag agtatttaga agacttggaa aaaggagttg aacccattac ttgggaagaa
    40561 atgatgcatg atttaggctt gaaggatgaa taatttgtat aaattagttc caacaagacg
    40621 tttcatcaag caattgaaaa aattggaccg ttatacgcag aagctaatta caaactattt
    40681 acaaaccaat gttttggaag acccaagacg acacggaaag gctttggttg gtaatcgcgt
    40741 tggtcaatgg cgctatagaa ttggtaatta tcgagttatc gtacaaattg tagatgatga
    40801 attagtcgtt gctactctag aagttggtca tcggagagat atttattgaa ttaaagctga
    40861 gtaataacag tatagaaagt aaggatagta aaaatttgaa taaaaaatgg ttatttgcag
    40921 attattatga tacaacaatt attttacttg ctttaatctc tgttattctg gtattacttg
    40981 gatttgctga gatgattgat ttggacaatc cgccttatag tattattgat ttagtaatct
    41041 ggggtgtttt tgtaattgat tatagttggc gcttttttac gactaaaaga aaatggcgct
    41101 ttattcttga aaatattttt gatttattgg ctattctccc tttaaatgct atttttacag
    41161 tgtttcgatt agggcgtatc tttcgtttag ctaaactaac aaaattactg aaactgactc
    41221 gtttacttag aataattgga cttacaggta aattagaaag aaaaattagt agattcttac
    41281 ggacaaatgg cctgatttat atcttgtatg ttaatatctt tattgtttta gtagggagtt
    41341 cgattttatc cgttgttgaa gaaaaatcct tctcaaatag tctttggtgg gctcttgtga
    41401 cagtaactac tgttggatat ggggatattg ttcctgcttc catttttggg aaatggctag
    41461 cagttttact gatgcttgtc ggtattggaa caatagggat gttaacaagt gctttgacga
    41521 acttttttgt aaaggataat ccagatgaac agataaaact tgataaactc aaagatgaat
    41581 tatcgagcca aagaatatta ctagagaaac aatctgaaaa aatcgaagaa ctacattgaa
    41641 tgataaaaga tttagttgaa aaaatatcat aaaggtgaga caaaacaaaa cttgattcga
    41701 ggagaaatca agtaagtctt gacacaatag aacgcatatt atcaggtata aaaacttgat
    41761 actatgcgtt ttatagagaa ataaaataaa atctgaacaa atcaattagg aatttaaagc
    41821 attttataac aacgttttag agtgataggg tgctatttca acttcaacct actataatac
    41881 agaaaaaaat acaggaaaaa acaactccct gatgattcaa ggagttgtct atagttaaat
    41941 tagtttttag aagcttcttg gaattctgga tttttccatg cttcgtcaat aatagcttgc
    42001 aattctttag cagatgcttg cattttttga gtttctgcat cgttcaatgg aatgtttact
    42061 ggacgaacga taccatgtgc accaacaaca gctggttgac cgataaagac attctcaact
    42121 ccgtattgac cttcttggaa tactgaaagt ggaagtactg cgttttcatc gtcaaggatt
    42181 gctttagtga tacgagcaag ggctactgcg ataccgtagt atgttgcacc ttttttgttg
    42241 atgattgtgt aggctgcatc acgaacacct tcgaacaatt caatcaattc agcttcttga
    42301 acattttgag tgtctttaag aaattcttca aggtttacac cagcgatgtt agcgtgtgac
    42361 caaacagcga actcagagtc accgtgttca cccatgatgt aggcgtgcac tgaacgagca
    42421 tccacatcca atttttcagc aagtgcttga cggaaacgag ctgagtcaag tgaagtacct
    42481 gaaccgataa cgcgttcttt agggaaacca gagaatttcc aagttgagta agtcaaaacg
    42541 tcaactgggt tagcagcaac aaggaagata cctttgaaac cagattcaac aacttgagtt
    42601 acgattgatt tgttgatagc aaggttttta cctacaaggt caagacgagt ttcacctggt
    42661 ttttgaggtg cacctgcagt gatcacaaca aggtcagcgt ctgcacagtc agagtattga
    42721 gctgcataga tttttttagg tgaagtgaag gcaagggcgt gactaaggtc aagcgcatca
    42781 ccaacagctt tttcatgcaa ttgtggaatt tcgataattc caagctcttg tgcaattcct
    42841 tggttaacaa gtgcaaaagc gtaagatgaa cctacagcac catcaccgac aaggataact
    42901 tttttgtgtt gtttagttga agtcattgtt ttaaacatct ccttaatttt attaggggat
    42961 tttccctaga caacttcatt ctatcacttt taaaaaactt tgtcacgaat atgccttata
    43021 gttctcgatg taaacgtttt agtggtttag aggctgaaat agatgggaat ttatggtata
    43081 atgttgttac ttactaattg tgaaatgagg catttattaa tgcaggataa aaatttagtg
    43141 aatgtcaatc tgacaaagga gatgaaggca agttttatcg actacgccat gagtgttatc
    43201 gtagcgcgag ctcttcctga tgttcgagat ggcttaaaac ctgttcaccg tcgcattctc
    43261 tacggaatga atgaattggg tgtgacccca gacaaacccc ataaaaaatc tgctcgtatt
    43321 acaggggatg tcatgggtaa atatcaccca cacggggatt cctctattta tgaagccatg
    43381 gtccgtatgg ctcaatggtg gagctaccgt tacatgcttg tagatggtca tgggaatttt
    43441 ggttccatgg atggagatag tgctgccgct caacgttata ccgaggcacg tatgagcaag
    43501 attgctctgg aaatgcttcg tgatatcaac aaaaatacag ttgatttcgt tgataactat
    43561 gatgccaatg aacgggaacc cttggtcttg ccagcgcgtt ttccaaacct tttggttaat
    43621 ggagcaactg gtatcgcggt tgggatggca accaatattc cacctcataa tctgggtgaa
    43681 accattgatg cagtgaagtt ggtcatggat aatcctgaag tgactaccaa ggacttgatg
    43741 gaagtcttgc ctggaccaga ttttccaact ggtgctcttg tcatggggaa atcaggtatc
    43801 cataaggctt atgaaacagg taaaggttcg attgtcctac gttctcgtac agagattgaa
    43861 acgactaaga ctggtcgtga gcgtatcgtt gtaacagaat ttccttacat ggtcaataaa
    43921 accaaggtgc atgagcatat tgttcgcttg gttcaggaaa aacgcattga gggtatcaca
    43981 gcagtacgtg atgagtcaaa ccgtgaaggt gttcgatttg ttattgaagt caagcgcgac
    44041 gcctcagcca atgttattct caataacctc ttcaaaatga cccaaatgca aaccaatttt
    44101 ggtttcaata tgctcgctat ccaaaatggt ataccgaaaa ttttgtctct tcgtcagatt
    44161 ttggatgctt atatcgagca ccaaaaagaa gtggttgttc gtcgtacacg ttttgataag
    44221 gaaaaagcgg aagcgcgcgc tcatatctta gaaggtctct tgattgcgct agaccatatc
    44281 gacgaagtga ttcgtatcat ccgtgctagt gaaacggatg cggaagctca agctgagttg
    44341 atgagcaagt ttaagctttc tgaacgtcaa agtcaagcta tccttgatat gcgtcttcgt
    44401 cgtttgacag gtttggaacg cgataagatt caatctgagt atgatgacct cttggctctg
    44461 attgcggatt tagcagatat tcttgctaag cctgaacgtg tttctcaaat tatcaaagac
    44521 gaattggatg aagttaaacg taaattttct gataaacgcc gtacagagtt gatggttgga
    44581 caggtcttga gtctcgagga tgaggacttg attgaagaat cggatgtctt gattaccctt
    44641 tctaacagag gctacattaa gcgtttggat caggacgagt tcactgctca aaaacgtggg
    44701 ggtcgtggtg tccaaggaac gggagtgaaa gatgatgact ttgttcgtga gttagtgtca
    44761 actagcaccc atgatcatct gctcttcttc acaaacaagg gacgtgtcta tcgtcttaaa
    44821 ggttatgaaa ttcctgagta tggtcggact gccaaagggc taccagtagt caatctcttg
    44881 aaattggatg aagacgaaag tattcagacg gttatcaatg ttgagtctga tcgcagtgat
    44941 gatgcttatc tcttctttac aacccgtcac ggtattgtga agagaaccag tgttaaggag
    45001 tttgccaata ttcgtcaaaa tggtctcaaa gcgctgaatt taaaggatga agatgagtta
    45061 atcaatgtct tgttggcaga aggagatatg gatattatca ttggtaccaa gtttggttat
    45121 gcagttcgct ttaatcaatc agccgttcgt ggtatgagcc gtatcgccac tggtgtgaaa
    45181 ggtgttaacc ttcgtgaagg agacacagtt gttggtgcca gcttgattac tgatcaagat
    45241 gaggttcttg ttatcacaga aaaaggatat ggtaagcgta cagtcgctac tgaataccca
    45301 acaaaaggtc gtggtggtaa gggaatgcag acagctaaaa ttaccgaaaa aaatggcttg
    45361 ctggccggtc ttatgactgt tcaaggggat gaggatttga tgattatcac tgatacaggt
    45421 gtcatgattc gaaccaatct tgccaatatt tcacaaacag gacgtgcaac tatgggagtt
    45481 aaagtaatgc gcctggatca agatgctcag atagtgactt tcacaacggt tgcggtggca
    45541 gaaaaagaag aagttgggac agaaaacgaa acagaaggtg aagcataatg tctcaaaaaa
    45601 ataataaaaa gaaaaacaag cgaaaaaatt tgctgacaaa tatcctagca ggatttctga
    45661 tattactgtc actggctttg atttttaata ctcaaattcg aaatattttc atagtctgga
    45721 ataccaataa gtatcaagtt agccaggtat caaaagaaaa attagaagaa aatcaggata
    45781 cagaaggcaa ttttgacttt gattctgtca aagctatctc ttcggaagct gttctaactt
    45841 ctcaatggga tgctcaaaaa ttaccagtta ttgggggaat tgcaattcct gaattggaaa
    45901 tgaatttgcc gatttttaaa ggacttgata atgttaatct cttctacgga gctggtacaa
    45961 tgaaacgcga gcaagtaatg ggagaaggaa attatagtct agctagtcac catatctttg
    46021 gtgttgataa tgctaataaa atgttatttt ctcctttaga taatgctaaa aatggcatga
    46081 agatttatct aaccgataaa aataaagttt atacttatga aatacgtgaa gtcaaacgtg
    46141 tgacaccgga tcgtgttgat gaagttgatg atagagatgg ggtcaatgaa atcacattag
    46201 taacctgtga agaccttgct gctacagaac gtattattgt caaaggtgat ttgaaagaaa
    46261 caaaagatta ttcacaaaca tctaatgaaa tcctaacagc tttcaatcaa ccatataaac
    46321 aattttatta atacaaatca gtgaaatcca tgatttcact gattttttaa gattttcata
    46381 aaaatatagt aaaatgaaat aagaatagga cgaatcgttc aggacagtca aatcgatttc
    46441 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat aaacttttat
    46501 gaaatacaga aaacgcttcc taaaacctaa agtttgtgat ataattatca agaaaaaaga
    46561 tttaggagtt tattatgatt tcttcagaat ttatctcaaa gattgaattt gcttgcaata
    46621 agaaagaaag tctttatagt caaagcaaat ttaagtatgc gattcgttcg atgttcgcag
    46681 gtgcattttt aaccttcagt actgctgcag gtgcagttgg ggctgacttg attaataaaa
    46741 ttgcaccagg tagtggacgc ttcctctttc cattcgtttt tgcttggggc ttggcctaca
    46801 ttgttttttt gaatgccgag ttggtcactt caaacatgat gttcttgact gctggtagtt
    46861 tcttaaaaaa aatctcttgg agaaaaacag ctgagatttt actatactgt accttgttca
    46921 accttatcgg agccttgata gcagggtggg gctttgctca ttcggcagcc tatgcgaatc
    46981 tgacacacga tagtttcatc tcaggtgttg ttgagatgaa gttaggccgc tcaaatgaat
    47041 tggtcttgct tgaggcgatt ttggcaaata ttttcgtaaa tattgcgatt ctgtcattta
    47101 ttttggtcaa agatggtggt gccaaacttt ggcttgtgtt gtcagctatt tacatgtttg
    47161 tattcttaac aaacgagcac attgcggcga actttgcttc tttcgcgatt gtgaaattca
    47221 gtgttgctgc ggattcaatt gccaacttcg gtgttggaaa tatgcttcgc cactggggtg
    47281 tgactttcat cggaaacttt atcggaggag gcctcttgat gggtcttcca tatgccttcc
    47341 tcaataaaaa cgaagatact tatgtagatt aagaaaatga gcacgattga gtcgtgcttt
    47401 tttcattttc aaaataaggt aatagctatt tcttatatca aaatatagaa aactgatatt
    47461 tgtaaactat aactcaaggt gctacaatat ccttaataaa atgatatgga ggtcacctta
    47521 tgacttgtga ttttaaatct gaaactctac aactacatgc tggtcaagtt gtggctccag
    47581 ctactaagtc tcgtgcagtg ccgatttatc aaacaacatt ttttgttttt gatgacacgt
    47641 aggaaggtgc cgatctgttt gccttgagga aaccagggaa catttatact cgtatcacca
    47701 atcctacaac agctgccctt gaaggtggtg ttgaagcgct agcaacagca tcaggtatga
    47761 ctgcagtgac ttatacgatt ttggcgcttg cccatgctgg tgaccatgta gtggctgctt
    47821 cgactattta cggtggaacc ttcaatcttt tgaaagaacc ccttcctcgt tatggtatca
    47881 caacaacctt tgtcgatatt gataatttgg aggaagtaga agcagctatc aaagacaata
    47941 ccaagcttgt cttgattgaa accttgggta accccttgat taatattcca gacctggaaa
    48001 aactggcaga gattgctcat aaacatcaaa tcccacttgt gtcagacaat acttttgcaa
    48061 caccttattt gattaacgtc ttctctcatg gcgttgacat tgccattcac tctgcgacta
    48121 agtttatcgg tgggcatggt acaactattg gagaaataat tgtcgatagt ggtcgttttg
    48181 actggacggc ttcagggaaa ttccctcaat ttgttgacga gggtccaagc tgccacaatt
    48241 tgagttatac tcgtgatgtg ggtgcagcag cctttattat agctgttcga gttcaattgc
    48301 ttcgtgatac aggtgcagcc ttgtcaccat tcaatgcttt cctcttgcta caaagacttg
    48361 aaaccctttc acttcgtgtg gaacgccatg tacaaaatgc tgagacaatt gttgattttc
    48421 ttgtcaacca tcctaaggta gaaaaggtaa attatccaaa acttgcagat agtccttatt
    48481 atgccttggc tgagaaatac ttgccaaaag gtgtcggttc aatctttacc ttccacgtca
    48541 aaggtgacga ggaagaagca cgcaaggtca ttgataattt agaaatcttt tctgaccttg
    48601 caaacgcggc agatgctaaa tcgcttgttg tccatccagc aacaatcact cacggtcaat
    48661 tgtcagaaaa agacctagaa gcagcaggtg tcacaccaaa tcaaatccac ttgtctatcg
    48721 gtcttgaaaa tgtagaagat ttgattgaag acttacgctt ggccttggaa aaaatttaaa
    48781 gtaaaagaag ataaacagtg ggttttgact cactgttttt gattttccct caggcatgat
    48841 ataatggtta cagaagtcta gaaagaggaa tgtaatgaac gaaatcaaat gtcccaactg
    48901 tggggaagtc tttacagtaa atgaaagcca gtatgctgaa cttttgtccc aagtgagaac
    48961 ggcagagttt gataaggaac tacacgatag gatgaggcag gaactggcct tggctgagca
    49021 aaaggctatg aatgagcaac agactaaact ggctcagaag gatcaagaaa ttgcgcaatt
    49081 gcagagtcaa atccaaaact ttgatacaga aaaagaattg gccaagaaag aagttgaaca
    49141 gacaagccat caggccttat tggctaagga caaggaagta caggccttgg aaaaccagtt
    49201 ggcgaccttg cgtttggagc atgaaaatca attgcaaaag accctttctg acctagaaaa
    49261 agaacgcaat caggtcaaaa atcagctcct actgcaagaa aaggaaaatg agttgtcttt
    49321 ggcttctgtt aagcaaaact acgaagccca gctcaaagca gccagtgaac aagtcgagtt
    49381 ttataagaat tttaaggctc aacaatctac aaaagcgatt ggggaaagcc tagaacagta
    49441 tgcagagagt gagtttaaca aggttcgtag tttcgccttt ccaaatgctt actttgagaa
    49501 ggataacaag gtctcttcgc gtgggtctaa aggggacttt atcttccgtg agtgtgatga
    49561 aaatggagtt gaaatcattt ctatcatgtt tgagatgaaa aacgaagcgg acggaacaga
    49621 gaagaagcac aagaatgcag atttttacaa ggaattggac aaggaccgtc aggagaagaa
    49681 ctgtgagtat gccgttttgg tgaccatgct tgaggccgat aatgactact ttaacacagg
    49741 gattgttgac gtcagccacg agtatgaaaa aatgtatgtt gttcgtcctc aattctttat
    49801 ccagttgatt ggtctcttac gtaatgcggc gctaaattcc ctaaaataca agcaggagtt
    49861 ggccttggtt cgcgagcaaa atattgacat tacgcatttt gaggaagatt tggatgcctt
    49921 taagctagct tttgctaaga actataattc agcttcgact aactttggaa aagctattga
    49981 tgaaatcgac aaggccatca aacgcatgga agaggttaag aaattcctga ctacatctga
    50041 aaaccaactc cgtctagcta acaacaaatt ggaagatgtc tctgttaaaa aattgacccg
    50101 gaaaaatcca acaatgaaag cgaagttcga agcactgaag ggggagtaga aagcaaaaat
    50161 gaacggtatt atcaacttaa aaaaagaagc aggaatgacc tcgcatgatg cggtttttaa
    50221 actgcgtaag attttgggaa ccaagaaaat tggtcatggt ggaaccttgg atccggatgt
    50281 ggtgggtgtt ttgccgattg cggttggcaa ggcgacacgc atggtcgagt ttatgcagga
    50341 cgagggtaag atctatgagg gggaaattac tctgggttat tccacgacga ctgaggatgc
    50401 tagtggggaa gtgatcgcag aaacccctgt tttgtctccc ttgtatgaaa agcttgttga
    50461 tgaagcgatt gctagcttga ctgggcctat tacccagatt ccccctatgt attcggcagt
    50521 taaggttaat ggtcgcaagc tctatgagta tgcgcgtgct ggtcaggaag tggagcgtcc
    50581 agaacgtcag gtgatcattt atcaatttga gcgaacaagt ccgatttctt atgatggcca
    50641 acttgcccga ttcacttttc gtgtaaaatg cagtaaaggg acttacatcc gtactttgtc
    50701 agttgatttg ggtgaaaagc ttggttatgc ggctcatatg tcccatttga ctcgtactag
    50761 tgctgctggc ttacaattag aagacgctct ttccttggag gaaattgctg aaaaagtaga
    50821 ggctgggcaa ttagattttc tccatccttt agagattggg acaggtgacc ttgtcaaagt
    50881 tttcctaact ccagaagagg ctacagaagt tcgctttggt cgttttattg agctagacca
    50941 aacggacaaa gaactggctg cctttgaaga tgataaattg ttagccattc tagaaaaacg
    51001 gggcaatctc tataagccaa ggaaggtttt tagctagatc gtttaggaat aaaaatcggg
    51061 tgatagataa caattgcttg ataaaacccc atactaatag tagaatggtt ttgggaatta
    51121 taatattcca attgttgcga gttgtaggta ctcaaataat ctatatagaa atttagaggt
    51181 gtgaaatgaa gcaatttaaa attctttcag ataaatattt agagtccatt acaggttctg
    51241 gtgggaactt aggcccagga tttggtgtga taattccatg atgcgaaatg agtttcgaga
    51301 aagggtggag caacttcttc aacaaaaaga aataaatgaa aatagtgagt tgagtcacct
    51361 gtttcgtctt gctatacaaa atttagacag aaatgaaaaa taccaatcgg tcatggccaa
    51421 tttgagtcaa gggttgtcac tttacctcat gacgcatcat taccaggcac ctaagtctgt
    51481 cattgatttt ggtttatgga ttgccaaagc tcctagccag gaaagaggga gactggcttt
    51541 cttgcagatg cttgctcaaa ccctacaggg ctttcgttaa aactgtcgaa catcagaggg
    51601 aagactctgg tgttttttgc tgatgagact ataaattttg taaaaaatgt gatagaatag
    51661 acgacggata aaataacgga ggatagcatg caaaatagac caatcattat tggagtgaca
    51721 ggtggttctg gtggtggtaa aaccagtgtt tcaagagcca ttttatcgca ttttcctgat
    51781 gaaaagattt ccatgattga gcatgattca tactacaagg atcagtctca tttgaccttt
    51841 gaagagcgtg tcaaaaccaa ctatgaccat ccttttgcct ttgatacaga cttgatgatc
    51901 gagcagatta aggaattgtt ggcagggcgt ccggtggaca tcccgaccta cgactataca
    51961 gagcatacac ggagtagcaa gacctatcgt caggagcctc aagatgtctt tatcgttgag
    52021 ggcattttgg tcttggagga caagcgtctg cgcgatttga tggatatcaa gatttttgtg
    52081 gatacggatg acgatgtgcg cattattcgt cgtatcaagc gtgatatgga ggagcgtggc
    52141 cgtagccttg atagcgttat taaccagtac ttaggtgtgg tcaaaccaat gtaccaccag
    52201 tttatcgagt caactaagcg ttatgctgat atcgtcattc ctgaaggggt tagcaatacc
    52261 gtggctatcg acctgttgac gaccaagatt gcaaagattt tggaagaagc tcgaaacagc
    52321 aaataatcac atgtggaggc cttgcctcct ttttctattt ttccctcata atggtacata
    52381 aatggagatt tttaggcata tttttggtat aataataccc atgaaagagc aagtaaatga
    52441 atagtaggtg gagatggaaa agtatttatc ggtaacaact ttgaccaagt atctgaaaat
    52501 gaaattcgat aaagacccat acttggaacg ggtctattta actggtcaag tttccaactt
    52561 tcgtaaacga cctactcacc aatatttctc cctaaaggat gaccatgcag ttattcaagc
    52621 gaccatctgg tctgggattt atcagaaatt agggtttgac ctggaagaag gaatgaagat
    52681 caatgtgatt gggcgtgtac aggtctatga accaagtggt agctactcca tcatcattga
    52741 aaaagctgag cctgatgggg ttggggcgct tgcgattcag tttgaacaac ttaagaaaaa
    52801 attgacagaa gaagacctgt ttcaagaacg cttcaagcaa gctctgcccc aattttctaa
    52861 gagaattggt gtagtaacca gccgtagtgg agccgttatt cgagatatta tcacgaccgt
    52921 cagcaggcga ttcccaggtg ttgacatcct tctttatccg accaaggttc aaggtgaagg
    52981 ggctgcggag gaaattgcta gaaatattgc gcgtgctaat caacgggacg atttggattt
    53041 gctcattatt ggtcgtggag gtggttctat tgaggatctc tgggccttta acgaagaaat
    53101 tgtggtacga gctatttttg aatctcgttt accagttatc tctagtgtgg ggcatgagac
    53161 ggatgtgacc ttggcagatt ttgtggcaga tcgacgcgct gcaacgccaa cagcggcggc
    53221 tgaactggca acacctgtga ccaagttgga tgtattagct catttgcaaa atcaggaaaa
    53281 acggatggca acggcagtcc gaaatgttct atctaagaaa caagaggctt tgaaaaaatg
    53341 cagtcagtct gttatcttta gacaacctga gcgcttgtat gacggttatt tgcaacgctt
    53401 ggaccaactg caactgcgtt tgaaacaaag tttgcgaact cggatttctg ataacaaaca
    53461 attagttcaa gcaagaactc atcaattagt acaattatca cctgttacca aaatccaacg
    53521 ctatcaagac cgtttaggac agttggacaa gctcttaggt agccaaatgg cgttagttta
    53581 tgacgccaag gttgctgagg ccaagcgact ttcggaagct ttgctcatgt tggatactag
    53641 ccgaatcgtg gcgcgtggtt atgctattgt caaaaaagaa gagtccgttg tagattcggt
    53701 tgagagtttg aagaaaaaag accaagtaac gcttttgatg cgagatggtc aagtagaatt
    53761 agaggttaaa gatgtcaaaa caaaagaaat ttgaggaaaa tctagcagaa ctggaaacca
    53821 ttgtccaaag tttggaaaat ggtgaaattg ctctggaaga tgcgattact gcctttcaaa
    53881 agggcatggt cttgtcaaaa gagctccaag ctacgctgga caaggctgaa aagaccttgg
    53941 tcaaggtcat gcaagaagac ggaacagaaa gtgattttga atgaaaaagc aagaaaaatt
    54001 agctcttgtc gagtcggctt tggaagattt ttatggagac cagcagtttg cctctagttt
    54061 acgggagtct gttctctatt ctattcatgc tggtggcaag cgtattcggc cttttctctt
    54121 gttagaagtt ctggaagcct tgcaggttgc catcaaacct gctcacgcgc aggtagctac
    54181 tgccttggag atgattcata cagggagctt gattcacgat gaccttcctg ctatggatga
    54241 tgacgattat cgaagagggc ggttaaccaa tcacaagaaa ttcggtgaag ctatggccat
    54301 tttggctgga gatgccttat tcttagaccc atatgccttg attgcgcagg cagatttgcc
    54361 aagtcagatc aaggtggact tgattgccaa cttatccctt gcttcaggta gtctgggtat
    54421 ggtggcaggg caagttttgg atatggaggg cgaacaccag cacttgtctc tggaagaact
    54481 tcagactatt catgccaata agactgggaa gttactagcc tatcccttcc aagcggcagc
    54541 tattatagct gaattgtcac ctgaaatgca ggtgaagctg aaaactgtgg gtgaattgat
    54601 tggacttgct tttcaagtca gagatgatgt actggatgtg acagctagtt ttgaggaaat
    54661 cggcaagaca cctcaaaagg atctgcaggc agaaaaatca acctatcctg ccttgttggg
    54721 cttggaagag tccattgcct tttgtaacca aaccctggat caagctaatg aaaaattaga
    54781 agaaattgcc cagcagattc cctttgaaac agaatcgatt gtaagtgtag tagaaagttt
    54841 gagaatcaat ggctaaggaa agagtggatg tactagctta taaacagggg ttgtttgaaa
    54901 cgagagagca ggccaagcga ggtgtgatgg ctggcctagt cgtagcagtc cttaatggag
    54961 aacggtttga caagccagga gagaaaattc cagatgacac cgaattaaaa ctcaaggggg
    55021 agaaactcaa gtatgtcagc cgtggtggtt tgaaactgga aaaggccttg caggtctttg
    55081 atttgtcggt ggatggcgcg actacgattg atatcggggc ctctactgga ggttttaccg
    55141 atgtcatgct acagaatagt gccaagttgg tctttgcagt cgatgttggt accaatcagt
    55201 tggcttggaa attacgccaa gacccacgag ttgtcagcat ggagcagttc aatttccgct
    55261 atgctgaaaa gactgatttc gagcaggagc cgagctttgc cagtattgat gtgagtttca
    55321 tttcccttag tctgattttg ccagccttgc accgtgtctt ggctgatcaa ggtcaggtgg
    55381 tagcacttgt caaacctcag tttgaggcag gacgtgagca gattgggaaa aatggaatta
    55441 ttcgagatgc taaggttcat cagaatgtcc ttgaatctgt aacagctatg gcagtagagg
    55501 taggtttttc agtccttggc ttggactttt ctcccatcca aggtggacat ggaaatattg
    55561 aatttttagc gtatttgaaa aaagaaaagt cagcaagcaa tcagattctt gctgagatta
    55621 aagaagcagt agagagggcg catagtcaat ttaaaaatga ataaaaaaga gagacttgaa
    55681 aaaattagaa gattggtgac agattatcaa atcggcacgc aagaagaaat tgtagaacat
    55741 ttgaaagaag caggtatcac tgccactcag gcgacggtat cccgagatat caaagagtta
    55801 ggtattgtca aaattccttt gagagacaac acctatgtct acgaattacc aaaatcaatc
    55861 gtaaaaagtc tgcaactggc tgaagacaat atcgaatcgg ctgaattgat ggataagatg
    55921 atcaatctcc aagttattcc aggaaatacg gcttttgtaa aagctcagtt aatcgagact
    55981 tttgcagaca agatttttag ctgtttgact gatgatagct cgattttagt cattgccaga
    56041 agtggaagtc tagcagagga aatctttgaa caagtaaaaa attggtaggt ctatatgtta
    56101 cttgaaattt cgataaaaaa ctttgccatt attgaggcta tttccctcaa ttttgaaaag
    56161 gggatgactg tcctgactgg tgaaacgggt gcagggaagt cgattatcat tgatgccatg
    56221 aatatgatgt tgggagctcg tgcgacgaca gatgttattc gtcatggtgc accaaaggca
    56281 gagattgagg ggcttttctc agttgagaat agtcgtcttt tacaggaaat ttttgataag
    56341 caaggtttag aattaggtga tgaaattatc atccgtcggg aaatcttgca aaatggtcgt
    56401 agtatcagcc gtgtaaatgg tcagatggtt aatctgtctg ttttgcgagc tattgggcaa
    56461 catcttgtag atattcatgg tcagcatgac catgaggagt taatgcgtcc ccaactgcat
    56521 atccagatgt tggatgaatt tggtgatgcc gctttttggg acttgaaaga aacctatcaa
    56581 acgagttttg atgcctatcg gaaaatgcgc aagcaggttc tggaagtcaa gaaaaaccaa
    56641 caggaacaca aggcacgtat cgaaatgttg gaatttcaaa tggcagagat tgaggcagca
    56701 aacttgcagg ctggagaaga cttggctctc aatcaagagc gagataaact cctcaaccac
    56761 aaaaatattg cggatacact gaccaatgcc tacagtatgt tggacaatga agatttttca
    56821 agtctggcca atgttcgttc agctatgaat gacatggaaa gtgtcgaaga gtatgatcct
    56881 gaataccgtg aaatttcaag ctatctgtct gagacctact atgttttaga agacattagc
    56941 aaacgtttgg aagctatcat tgaggacctt gattttgatg gcaatcgcct gatgcaggtt
    57001 gagaatcgtt tggacctcct tcatactatt actcgtaagt atggtgggac tgttgatgat
    57061 gttttgcttt attttgccaa gattacggaa gaatacaatc tcttgacagg caataatctt
    57121 tcgtctgagg acatggaagc agagcttaag aagttggaag tcaatcttgt caatttggca
    57181 ggtcaacttg cttctgctcg tcataatttg gctcagcaac tcgaagctga gattaaacaa
    57241 gaactgcaag atctttatat ggaaaaagcc cagtttcagg ttcgttttag taagggaaaa
    57301 ttcagtcgtg agggaaataa aatggttgag ttttatattt caaccaaccc tggagaagac
    57361 tttaaaccct tggttaaggt tgcttctgga ggggaattat ctcgtctcat gttagccatt
    57421 aagtctgcct tttcacgtaa agaaggcaag actagcattg tctttgatga ggtggatacg
    57481 ggagtttcag gtcgtgttgc tcaagctatt gctcagaaaa ttcataaaat tggtcagcat
    57541 ggtcaggttt tggctatctc ccatttgcca caagtaattg cgattgcaga ttatcaattc
    57601 tttattgaga agattagtaa tgaccattca acggtttcga ctgttcgtct cttgacggtc
    57661 gaagagcgag tggaggaagt tgccaagatg ttggcaggtg atgatgtgac agaagcagcc
    57721 ctgacgcaag caagagaatt gttgagaaac agggagaaat aagatgacag attattatgt
    57781 aattggagat gttcacggaa aagctgggat gctggaagac cttctcaaaa cctgggatgg
    57841 tcagccccag ttgctctttc taggtgattt gattgacaga ggtgaggata gtcaccgtgt
    57901 tcttgaaatg gtcaaggact tggtggacaa tcaaggggct atctgtttgt ccggaaacca
    57961 cgagtatatg tttttgactt ggctagatga cccagaagaa agttatgacc attatagtcg
    58021 caatggtgga gatacaacca ttaactctat cctaggtcgt cccttggatg caccagttga
    58081 tggagtagaa gatgccaagc gggttgccgc tgaagcgtca gacttggtcg aattcattcg
    58141 tcaaatgcca tttgtagtag agacagacaa gtatatattt gttcacgcag gtattgattt
    58201 gactttggac gactggcatg aaacaacaga ttataaaaaa gtatggctta gaaaaccatt
    58261 ccacggagct gaaaatcata ctggaaaaac cattgtcttc ggtcatacac cggtctatgg
    58321 tttgttacag caagaacgcg gtacatctga gctttggact acagaagatg gcaagattgg
    58381 aatggatgga ggagctgttt atggtggtgt ccttcacggg attgtcttta cagaccaagg
    58441 aatgacagaa caccacttta tcgaaaatga cggctttgtc gctgaagatt agtactccta
    58501 gcagggtatg gtcttgtcaa aatatcaaaa acaatttata ataaatagat accctgaaag
    58561 gaagagaatc atgaacttag aagaattgaa aaaacgacag gggaagatcc gtaacttctc
    58621 tattatcgcc catattgacc acgggaaatc aactctagca gaccgcattt tggaaaaaac
    58681 agagacggtt tcaagtcgtg aaatgcaggc ccagcttttg gatagcatgg atctagagcg
    58741 ggaacgtgga attactatta agttgaatgc catcgagttg aattacactg caaaagatgg
    58801 ggaaacttat attttccact tgattgacac accagggcac gttgacttta cctatgaagt
    58861 ttcacgttcg ctagctgcct gtgagggtgc tattttggtg gtcgatgcgg ctcaaggaat
    58921 tgaggctcaa actcttgcca acgtttatct ggctttggat aatgatttgg aaatcatgcc
    58981 tatcattaat aaaattgacc tgccggctgc agatccggag cgcgtgcgta cagagattga
    59041 agatgtgatt ggtttggatg ccagtgaagc agttttggct tctgccaagg ctggtattgg
    59101 gattgaagaa atcctcgagc aaattgtaga aaaagtacca gcaccaacgg gtgatgtgac
    59161 ggcgccactt aaggccttga ttttcgactc tgtttacgat gcttaccgtg gggttatcct
    59221 ccaagtgcgt gtcatggacg gagtggtcaa acctggtgat aagattcagc tcatgagcaa
    59281 tagtaagacc tttgatgtgg ccgaagtcgg tatttttaca ccaaaagcgg ttggtcgtga
    59341 tttccttgcg actggtgatg ttggttacat tgcggcgtct atcaagacgg ttcaggatac
    59401 tcgtgtgggt gataccgtta ccttggcaac caatcctgcg gcagaaccat tacatggtta
    59461 taagcagatg aatcctatgg tctttgcggg tctctaccca atcgaatcaa acaagtacaa
    59521 tgacctgcgt gaagcgcttg aaaaattgca actgaatgat gctagtcttc agtttgaacc
    59581 agaaacatct caggcacttg gatttggttt ccgttgtgga tttcttggac ttctccatat
    59641 ggatgttatt caggaacgtt tagagcgtga gttcaatatt gacctcatca tgacagctcc
    59701 gtctgttatt tacaaagtta atttgaccga cggtgagtct atggatgtgt ctaacccatc
    59761 tgagtttcca gacccaacta agattgcgac cattgaagag ccttatgtca aggcgcaaat
    59821 catggtacca caggagttcg tcggagcagt aatggagcta gctcagcgta agcgtgggga
    59881 ctttgtgact atggactata ttgatgataa ccgtgtcaat gttatctatc aaattcctct
    59941 tgctgaaatt gtctttgact tctttgataa acttaagtct tcgacacgtg gttatgcaag
    60001 ctttgactac gaattgtcag aatatcgccc atctaagctg gtgaaaatgg atatccttct
    60061 caatggagat aaggtggatg ccctcagctt tatcgttcac aaggactttg cctacgaacg
    60121 tgggaaactc atcgttgata aactcaagaa aatcatccct cgccaacaat ttgaagttcc
    60181 aatccaagcg gctattggac acaagattgt cgctcgtact gatatcaagg cccttcgtaa
    60241 gaacgtgctt gctaaatgtt atggtggtga cgtttctcgt aagcgtaaac tccttgaaaa
    60301 acaaaaagct ggtaagaaac gcatgaaatc catcggatca gttgaagttc cgcaagaagc
    60361 cttcctcagc gtcttgagta tggatgaaga ataagttatc agaaatgcct ttccttgttc
    60421 acaggaaatt tatataaaaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    60481 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
//
LOCUS       DBEJNA010000008        59902 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEJNA010000008 DBEJNA010000000
VERSION     DBEJNA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 59902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.08"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(74..2032)
                     /gene="ftsH"
                     /locus_tag="ACL3JB_000556"
     CDS             complement(74..2032)
                     /gene="ftsH"
                     /locus_tag="ACL3JB_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0685349.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2048..2590)
                     /gene="hpt"
                     /locus_tag="ACL3JB_000557"
     CDS             complement(2048..2590)
                     /gene="hpt"
                     /locus_tag="ACL3JB_000557"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0685350.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2594..3871)
                     /gene="tilS"
                     /locus_tag="ACL3JB_000558"
     CDS             complement(2594..3871)
                     /gene="tilS"
                     /locus_tag="ACL3JB_000558"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0685351.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3868..5136)
                     /locus_tag="ACL3JB_000559"
     CDS             complement(3868..5136)
                     /locus_tag="ACL3JB_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0685352.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQY
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5129..5251)
                     /locus_tag="ACL3JB_000560"
     CDS             complement(5129..5251)
                     /locus_tag="ACL3JB_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0685353.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5256..5624)
                     /locus_tag="ACL3JB_000561"
     CDS             complement(5256..5624)
                     /locus_tag="ACL3JB_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0685354.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5617..5883)
                     /locus_tag="ACL3JB_000562"
     CDS             complement(5617..5883)
                     /locus_tag="ACL3JB_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0685355.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5941..9450)
                     /gene="mfd"
                     /locus_tag="ACL3JB_000563"
     CDS             complement(5941..9450)
                     /gene="mfd"
                     /locus_tag="ACL3JB_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0685356.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKEIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQGYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRIKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9451..10020)
                     /gene="pth"
                     /locus_tag="ACL3JB_000564"
     CDS             complement(9451..10020)
                     /gene="pth"
                     /locus_tag="ACL3JB_000564"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0685357.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKKFEKTMQRYNG"
     gene            complement(10091..11206)
                     /gene="ychF"
                     /locus_tag="ACL3JB_000565"
     CDS             complement(10091..11206)
                     /gene="ychF"
                     /locus_tag="ACL3JB_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0685358.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11290..11484)
                     /locus_tag="ACL3JB_000566"
     CDS             complement(11290..11484)
                     /locus_tag="ACL3JB_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0685359.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKINKIID"
     gene            complement(11549..12685)
                     /gene="dnaN"
                     /locus_tag="ACL3JB_000567"
     CDS             complement(11549..12685)
                     /gene="dnaN"
                     /locus_tag="ACL3JB_000567"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0685360.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12844..14205)
                     /gene="dnaA"
                     /locus_tag="ACL3JB_000568"
     CDS             complement(12844..14205)
                     /gene="dnaA"
                     /locus_tag="ACL3JB_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0685361.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14418..15176)
                     /locus_tag="ACL3JB_000569"
     CDS             complement(14418..15176)
                     /locus_tag="ACL3JB_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0685362.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15234..16415)
                     /locus_tag="ACL3JB_000570"
     CDS             complement(15234..16415)
                     /locus_tag="ACL3JB_000570"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR0685363.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16598..17077
                     /gene="rlmH"
                     /locus_tag="ACL3JB_000571"
     CDS             16598..17077
                     /gene="rlmH"
                     /locus_tag="ACL3JB_000571"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0685364.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17121..17194
                     /locus_tag="ACL3JB_000572"
     tRNA            17121..17194
                     /locus_tag="ACL3JB_000572"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17155..17157,aa:Arg,seq:tct)
     gene            17359..17484
                     /gene="comC"
                     /locus_tag="ACL3JB_000573"
     CDS             17359..17484
                     /gene="comC"
                     /locus_tag="ACL3JB_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0685365.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17505..18830
                     /gene="comD"
                     /locus_tag="ACL3JB_000574"
     CDS             17505..18830
                     /gene="comD"
                     /locus_tag="ACL3JB_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0685366.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18827..19579
                     /gene="comE"
                     /locus_tag="ACL3JB_000575"
     CDS             18827..19579
                     /gene="comE"
                     /locus_tag="ACL3JB_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0685367.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19631..19702
                     /locus_tag="ACL3JB_000576"
     tRNA            19631..19702
                     /locus_tag="ACL3JB_000576"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19664..19666,aa:Glu,seq:ttc)
     gene            19708..19781
                     /locus_tag="ACL3JB_000577"
     tRNA            19708..19781
                     /locus_tag="ACL3JB_000577"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19742..19744,aa:Asn,seq:gtt)
     gene            complement(19822..20364)
                     /locus_tag="ACL3JB_000578"
     CDS             complement(19822..20364)
                     /locus_tag="ACL3JB_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0685368.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20543..22146
                     /locus_tag="ACL3JB_000579"
                     /pseudo
     CDS             20543..22146
                     /locus_tag="ACL3JB_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22176..24728)
                     /locus_tag="ACL3JB_000580"
     CDS             complement(22176..24728)
                     /locus_tag="ACL3JB_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0685369.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24790..26412)
                     /locus_tag="ACL3JB_000581"
     CDS             complement(24790..26412)
                     /locus_tag="ACL3JB_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685370.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26618..27643
                     /gene="trpS"
                     /locus_tag="ACL3JB_000582"
     CDS             26618..27643
                     /gene="trpS"
                     /locus_tag="ACL3JB_000582"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0685371.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27795..29273
                     /gene="guaB"
                     /locus_tag="ACL3JB_000583"
     CDS             27795..29273
                     /gene="guaB"
                     /locus_tag="ACL3JB_000583"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0685372.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29324..30421)
                     /gene="recF"
                     /locus_tag="ACL3JB_000584"
     CDS             complement(29324..30421)
                     /gene="recF"
                     /locus_tag="ACL3JB_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0685373.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSVQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNTTDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30424..30792)
                     /gene="yaaA"
                     /locus_tag="ACL3JB_000585"
     CDS             complement(30424..30792)
                     /gene="yaaA"
                     /locus_tag="ACL3JB_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0685374.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30951..32201
                     /locus_tag="ACL3JB_000586"
     CDS             30951..32201
                     /locus_tag="ACL3JB_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0685375.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            32198..33481
                     /locus_tag="ACL3JB_000587"
     CDS             32198..33481
                     /locus_tag="ACL3JB_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0685376.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFSWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33523..34344
                     /gene="rodZ"
                     /locus_tag="ACL3JB_000588"
     CDS             33523..34344
                     /gene="rodZ"
                     /locus_tag="ACL3JB_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0685377.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34355..34900
                     /gene="pgsA"
                     /locus_tag="ACL3JB_000589"
     CDS             34355..34900
                     /gene="pgsA"
                     /locus_tag="ACL3JB_000589"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0685378.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34897..35724
                     /locus_tag="ACL3JB_000590"
     CDS             34897..35724
                     /locus_tag="ACL3JB_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0685379.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35709..36548
                     /locus_tag="ACL3JB_000591"
     CDS             35709..36548
                     /locus_tag="ACL3JB_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0685380.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36541..37335
                     /locus_tag="ACL3JB_000592"
     CDS             36541..37335
                     /locus_tag="ACL3JB_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0685381.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTSFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37394..38212
                     /gene="mreC"
                     /locus_tag="ACL3JB_000593"
     CDS             37394..38212
                     /gene="mreC"
                     /locus_tag="ACL3JB_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0685382.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38212..38706
                     /gene="mreD"
                     /locus_tag="ACL3JB_000594"
     CDS             38212..38706
                     /gene="mreD"
                     /locus_tag="ACL3JB_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0685383.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38800..39978
                     /gene="pcsB"
                     /locus_tag="ACL3JB_000595"
     CDS             38800..39978
                     /gene="pcsB"
                     /locus_tag="ACL3JB_000595"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0685384.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40202..40981
                     /gene="rpsB"
                     /locus_tag="ACL3JB_000596"
     CDS             40202..40981
                     /gene="rpsB"
                     /locus_tag="ACL3JB_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0685385.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41060..42100
                     /gene="tsf"
                     /locus_tag="ACL3JB_000597"
     CDS             41060..42100
                     /gene="tsf"
                     /locus_tag="ACL3JB_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0685386.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42346..42669
                     /gene="tnpB"
                     /locus_tag="ACL3JB_000598"
     CDS             42346..42669
                     /gene="tnpB"
                     /locus_tag="ACL3JB_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0685387.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(42810..43097)
                     /locus_tag="ACL3JB_000599"
                     /pseudo
     CDS             complement(42810..43097)
                     /locus_tag="ACL3JB_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43079..43608
                     /locus_tag="ACL3JB_000600"
                     /pseudo
     CDS             43079..43608
                     /locus_tag="ACL3JB_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43683..44603)
                     /gene="cysK"
                     /locus_tag="ACL3JB_000601"
     CDS             complement(43683..44603)
                     /gene="cysK"
                     /locus_tag="ACL3JB_000601"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0685388.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44852..45487)
                     /locus_tag="ACL3JB_000602"
     CDS             complement(44852..45487)
                     /locus_tag="ACL3JB_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0685389.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45543..46841
                     /locus_tag="ACL3JB_000603"
     CDS             45543..46841
                     /locus_tag="ACL3JB_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0685390.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46838..47500
                     /locus_tag="ACL3JB_000604"
     CDS             46838..47500
                     /locus_tag="ACL3JB_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0685391.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47580..48128
                     /gene="raiA"
                     /locus_tag="ACL3JB_000605"
     CDS             47580..48128
                     /gene="raiA"
                     /locus_tag="ACL3JB_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0685392.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48264..50237
                     /locus_tag="ACL3JB_000606"
     CDS             48264..50237
                     /locus_tag="ACL3JB_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0685393.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50234..50686
                     /gene="rplI"
                     /locus_tag="ACL3JB_000607"
     CDS             50234..50686
                     /gene="rplI"
                     /locus_tag="ACL3JB_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0685394.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50730..52082
                     /gene="dnaB"
                     /locus_tag="ACL3JB_000608"
     CDS             50730..52082
                     /gene="dnaB"
                     /locus_tag="ACL3JB_000608"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0685395.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52084..52350
                     /locus_tag="ACL3JB_000609"
     CDS             52084..52350
                     /locus_tag="ACL3JB_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0685396.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52439..53785
                     /gene="cbpD"
                     /locus_tag="ACL3JB_000610"
     CDS             52439..53785
                     /gene="cbpD"
                     /locus_tag="ACL3JB_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0685397.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGETHYFMTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      53868..53970
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54041..54331
                     /locus_tag="ACL3JB_000611"
     CDS             54041..54331
                     /locus_tag="ACL3JB_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0685398.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54294..55052
                     /locus_tag="ACL3JB_000612"
     CDS             54294..55052
                     /locus_tag="ACL3JB_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685399.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            55091..56098
                     /locus_tag="ACL3JB_000613"
     CDS             55091..56098
                     /locus_tag="ACL3JB_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0685400.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEASKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56098..56826
                     /locus_tag="ACL3JB_000614"
     CDS             56098..56826
                     /locus_tag="ACL3JB_000614"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685401.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56945..57403
                     /locus_tag="ACL3JB_000615"
     CDS             56945..57403
                     /locus_tag="ACL3JB_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0685402.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57405..59837
                     /locus_tag="ACL3JB_000616"
     CDS             57405..59837
                     /locus_tag="ACL3JB_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0685403.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVYAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
BASE COUNT        18593 a        10315 c        11817 g        19177 t
ORIGIN      
        1 ttccattttc tccattctgt tccctttagc tcctaaactg cacaaaaaag agaggctcca
       61 gcctctctca gggttatttt tcgtcattca tttttgactt tacttcatca taggatagtg
      121 catgagattc ctcttctact gcttcaggca tctttcctgt ttcgtaaaga gctttaattt
      181 gtgtactatc caatgtttcg tatttcaata atgcttctgc aattaacttg tgagtttcac
      241 gatttgactg aataatttca gcagctttat ttcgtgcctc atttaataat gaacgaacct
      301 cttcatcaat ttcataagct gtttgttctg aaattgattt ttgaggactc tgtgcaccaa
      361 gcatagcatg gtttccttca tattgtactg ggccaagttt ttcactcata ccgtactctg
      421 taaccattgc acgtgccatt tgtgtcgctt gttcaaagtc gtttgaagct cctgtggttt
      481 ggacattaaa gataatttct tcagctacac gtccacccat taagccagcc aattgctctt
      541 tcatatcttc tttagataga agcatttgat cctctttagg aagtgcaatc atgtatccgc
      601 ctgcacggcc gcgtggtaca attgtaacct tatggacaac gcgagcattc gacaagacta
      661 gaccaacaat ggtatgtcct gcctcatggt aagcaaccaa ttctcgttct ttttgtgaaa
      721 ctgtcttatc tttcttagaa ggtccagcaa taactctatc ttctgcttca tcaatatctg
      781 aagcatcaat tatcgattta ttgcgacgag cagcaactaa agctgcttca ttcaagacat
      841 tctctaaatc agcaccaaca aagcctggag tttgttgagc cactaatttc aaatcaacat
      901 cttctgctaa aggcttattc ttagcgtgaa ctttcaagat tgcttcacga cctttaacat
      961 caggacgacc aaccaatact tttctatcaa aacgtcctgg acgcaaaagg gcagggtcaa
     1021 gtacatctga acggtttgtc gcagcgatga cgataatccc ttcatttccc tcaaaaccat
     1081 ccatctcaat caaaagttgg ttcaaggttt gttcacgttc gtcattacct ccgccgagac
     1141 cgactccacg ttgacgtcca acagcatcaa tttcatcgat aaagatgata gctggtgctg
     1201 cttttttggc atcctcaaaa agagagcgaa cacgactagc tccaactccg acaaacattt
     1261 ctacaaagtc agaacctgag atactaaaga atggaacacc tgcttctcca gcgactgcct
     1321 tagcaagcaa agttttacct gtccccggag gtccctccaa aagaacacct gctggaatac
     1381 gggctccaag ttttgtgaat cgttttggat cttttaagaa ctcaacaact tcaactagtt
     1441 cttgtttttc ttcttcagct ccagcaacat ctgaaaatct tactttaata tcttctttat
     1501 ttgctgcttt agccttacta cgtccaaaac tcattggatt acggccattg cctcctccca
     1561 tatttcccat catagagaat aggaagaaga atagaattcc aaatggcaca atggatacga
     1621 gtagattaat ccatatacca cttgaacttt catgcttaac agttacttct gctttatggt
     1681 cagtagcaag tttttgcaat tctgatacgg tagtatctgc aggaagaata gtgctggtaa
     1741 atttctctac cttagtaaca gatggcgtga aaaactgaat acctgttcct tctttacttg
     1801 ttttaggatt tttatagaca ccagaaactt cgataacact accatttggt tggtaagtta
     1861 attcttttac attaccatcg gtaatttctt gtaccaactc agtatagttg atttgctgac
     1921 ttcctcctga gttattccca gaatagaaat actggaatcc tgtcacaagg aaaaagataa
     1981 ataataacca tagaaaagga tttttaatta aaccattatt ttgttttttc attaaagatt
     2041 attctttcta atttgaatac acttcctctt tcaatactcc aatataagga agattacgat
     2101 aattttcttt gtagtctaaa ccataaccta ctacaaactc atttgggata gtaaagcagg
     2161 tatagtctgc ctcaatttct acaacacgtc cttctggttt atccaacaag gttgcaattt
     2221 taacagaagc tgcttctctt tctttaaaca tatctcgcaa attcttcaaa gtttgacctg
     2281 tatcaatgat atcttctaca aatagaacat gtcttccttt gatatcttga gtcacatctt
     2341 gtttaatatt gataacacca ctacttgctg ttccaccatg gtagctagaa accatcatga
     2401 agtccatttc aatatgtgta tcaatatgtt tgaccaattc agccataaaa ggaatagatc
     2461 cttttaaaat cccaactaag attggatttt ttcctgcata gtctttagtt aattgagcac
     2521 ctagtttttt agctgcttct gtaatttcat cgtgtgaaac gaggactttt ttaatatcgt
     2581 tttctaacat tttttaccta tctatttttt ctatataaag tacagtgttc attatatcat
     2641 ttttcgtttt tttactcaaa ttattggtcg caattcccaa aattgagaca atttcaccaa
     2701 attgctcaat aataagagca gagtttctct tttccatagg gattttcaaa tcaataaata
     2761 aacgtctgag tttttttcta tgcccatttt gaatcaaaac atctcctgtt tttcgatgac
     2821 gaatgtgtat ggatgtttca cgtgaaacag gtatttgttg aattaattca ccttctaatg
     2881 gaagtccaaa ggaaaataaa tatccttgat aagctacctg attttgatag tgtaacacaa
     2941 gttcatcttc cttttcatca gcctgcggac tgattttaca aatctgaaac tgttggtact
     3001 cttttatcaa ttcatagcca tttttaatcg gatgacgata ctggctttta gattttaaaa
     3061 tctgctgaac ttcagcaaac tgagcttttg taagattcaa atctggaaaa cgattcagat
     3121 aagtttgaag taaaactctt tgtgtagact cagagtaaga aaataactgc tgtaaatctt
     3181 ccacattaat attgttagat aattcagcta ttgccaaatc ataatctaaa atttcattgc
     3241 caatgcctaa gattgcatcc ctaaatcgag gattttcttt ttccaattct ggtaagtaag
     3301 agtttcgaat acgatttcga aaataatgat tctcctgatt tgatgtatct tcaaagtgaa
     3361 aaattgatgg aaagtctttt ttctgaaaat gcaagaaggg acgaatgatt tctatctctc
     3421 cgactacttg cttctcctta attcctgata gatagcgcaa gcgagttcct cgaatcaagc
     3481 gcatcaaaat cgtttccacc tgatcatcag catggtgggc agtgactaaa gctgtcgcac
     3541 ctgtcttttt cataacctct tgaaaaaaat cataacgaaa atttcgtgca cgcgcttctg
     3601 aaaattctcc tgaaaaattg ctgatataaa taggaagctc tgcttcagca gccaacttcc
     3661 ttaattcctt ttcttcccaa tctgattcaa ttctctgctt atgattcaca tgagccagaa
     3721 tcaattcaat ctctaactct ttttgataag tagacaatac cttaaataga aacatagaat
     3781 ctaatccacc agaaagagct agaaccgcct tagcatgctt tttgaaatat cccttcttga
     3841 gaaaatgatt taaaaaatct ggttccctca ttttagaacc tcataaacat ccttggctat
     3901 cttagaaatc gtatcataat cagaattctt agtgaaaata gaaagaataa atggagaatc
     3961 tgcatagaca acacccgtat catgcttaaa ttcatccgca tctccaattt tatgagctac
     4021 tttaacagaa acacctttgg caattcgctg actatcaaaa tctgttttag tcaaagactc
     4081 tagcacaaat ccattttgat tataaatagc ttccataaac ttcccggcca tcttagaaga
     4141 aatcaatttt tcttttggat cccaatcatc tcccataatg gcagacatct tggatttgaa
     4201 tgtggcatca gattggtttg aaatgtaata tcccaataga ttatgagcta cattatcaga
     4261 ttcttttgat actttcgtaa ttaaatcctt taaagaatat tctttattat cttctttttt
     4321 aggaagacta ccacttccct ctggtttata agaacctgga aaatcattga ctgcagatac
     4381 gtattttaca gtcgtatcta actgataaag accctcattt attttttctt gcgtataata
     4441 gagataggag agtttcaaaa cgctggctgc atacatcttt tcatattgat tgataccagc
     4501 ttcttttcca gtagtcagtt gcttaacata aatagagaaa gaatctttct gatatttttc
     4561 agataacatt tcttgaactt tactcatccg attatcttct tcagaagttg attctttagc
     4621 tacccatcca gcctgatcaa tatgtagaaa ttctcttcct tctacaaaca tggtcttgtc
     4681 gattgatact tgcgaataag ctgataagga tgatttcact tcttttaaat cataaggact
     4741 attgtacagt ttaaagtcag attctaacca tacttttttt attgttggag ttacctctga
     4801 ttgatcatat aaaaatcgtt tgtccgcagc tataaattga tgatttgata gcttaaatac
     4861 tggaattcct tgtttattta agcgccactc ggttatttga aaacttgttt tgggagtcaa
     4921 tttcccagat tccactacta aatcttcatt cgcataaaca ggaacctctc cataaaccat
     4981 gggagaactt aatttttctc taaaataaat accaaagtca gattgtgaaa ggtaataaat
     5041 ttctttcgaa gtatagacga cttctttttc tgtgctaacg acttttgaaa tggtcaaaaa
     5101 acttggtagc aacaaaataa ttaagaattt acgcattctt cctttccttt tcttcttgta
     5161 aacgcaataa ttgattttta tcagccaatt cttccagctt ttcatctgac aaactcaaaa
     5221 attgctctat tacgtctaat aaattttcca ttttatcacc tttgaagcaa gtcaggaatc
     5281 gtataaactt tttccctcga cttagaataa tagtacttcg ctcgtgtata tttagcagca
     5341 taatcttcat ctttcaactt ggtagcaaat gctgtctcct tatccttttc atcactcaaa
     5401 gtttgatact gagtttgcaa gtctgctaat tgctgacgtc tttggagtaa ttgctgataa
     5461 ctctgcgcta aattaaaagt tggcaagata aataatagca taatcaaaat caatacccct
     5521 cccataaaac gattccgttt ttgtcgttct ttcatcaggt agcgacgacg ttggtattca
     5581 ttttgaataa aagaattatt caattgtaca atatttttag acattttctt ctacccgtgt
     5641 ttcactgata atttcataca ttcctgctgc atcttctttt tttgtactat ctttcatctc
     5701 tagtactttt acaagcagca acttattgcc aaagcgaatt tcaacttggt cattaacttt
     5761 caagtccgtt gaacttttgg ccaagattcc attaaccttg attctacctt tatctgctac
     5821 ttcctttgcg actgtacgac gcttgataat tcgcgatact tttaaatatt tatctaatct
     5881 catccttatt acctcaattt attattgtac catttttatc tattttatag aagaaaaata
     5941 tcaaatggaa ttttcttcct tagactcttt tatctctaat aaactttctc caaaaatcag
     6001 caaaccttct aaaatttcat aatctttctt attttggaca tcaaatacaa gctccattaa
     6061 tcccttattc tcagcgatgc ctgcttttaa gttcgttacg gataaagctt taaaataatc
     6121 ttgagctaaa aacagtcgtt gagtgacttt ttcaaattga attgtaattt tattatcttt
     6181 tctttccaca cgttgaacaa agaccttgtc caagtatgat ttgaccaaac caatctctaa
     6241 cagataggct actacatctg ggtattctcc aaaacggtct atcaactcct cttgtaactc
     6301 ttcataattg acacggttgt caatttgacg aattttcttg taaatttcaa tcttatgtcg
     6361 ttgatcagaa atataagtat caggaagata ggcatcaatt tgcaaaatca actcagcatt
     6421 ccctttgatt cttgtgttag cgttagcatt accgtttcgt ttagcaatag cttcctctaa
     6481 taactgcgaa tacaattcaa aaccaacaga atcaatgaaa ccagactggg attttcctaa
     6541 aagatttcct gctccacgaa tcgaaagatc tcgcattgca atcttaaagc cagagcccaa
     6601 ttctgtaaat cctttaatcg cttctaatct cttttcagag acttcactga ttgatttttc
     6661 tggacgatac atgagataag cataagcaat acgattacta cgaccgactc ttcctcttaa
     6721 ctgatataag gttgacaagc ccatatggtc cgcattttca ataaataaag tattagcatt
     6781 tggaatgtcc acccctgtct caataatagt agtcgtcacc aagatatcgt attgtccctc
     6841 aataaagtct aatagagtat tttccaactg gacttcactc attcgaccat gaacatatcc
     6901 aatcgaagcc tctggaatca actcctgtaa ttctgaaacc ttctgaacaa ttgtgtcaac
     6961 tttgttgtaa agatagtaac cttgacctcc acgctccatt tcacgcaaga cagcatcacg
     7021 aatgacacta tcattctttt ccaaaacata ggtctgaaca gggtagcgat tagtcggcgg
     7081 agtttcaata acagacaaat ctctgattcc cagcatagac atatggaggg tacgagggat
     7141 tggcgtagcg gtcaaggtta ggacatccac ttgtttcttc agttctttca aagtttcctt
     7201 atgcttgaca ccaaatcgct gttcctcatc aataatcatc aagcccaaat cagcaaacac
     7261 aacatctttt gacaaaacac gatgtgttcc aatcaaaata tcgacttgac cgtttttcaa
     7321 tttttcaagt gttgcagtct gctctttttt acttctaaag cgactcaaca catcaacatt
     7381 aactgcaaaa ttttggaatc gttccttaaa attcgtatag tgctgttgcg ctaaaaccgt
     7441 cgtcggaact agaatgacaa cctgtttgtg atcattgact gctttaaagg ctgcacgcat
     7501 agcaacttca gtctttccaa aaccaacatc cccaactaaa agtcgatcca ttggctgaga
     7561 agcctgcata tccctcttga tttcctcaat actacgaagt tgatcatccg tttcaacata
     7621 agggaaagca tcatcaaagg catcttgatc atcatcatca gctgagaaag caaaaccctt
     7681 caactgacta cgttcagagt agagtttgat taaatcatca gctatatcct ctacctggtt
     7741 cttaaccttt tgcttggcct ttttaaaatg accgtcattt aatttattga gttttggagc
     7801 tttaccatca cttgaaatat atttggacag tagatgaatc tgttccacgg gaatagaaat
     7861 ttgatcacca ttttggtact ggacactgac ataatcacga tgaatttcct tgatttcaat
     7921 ggtttcaatt cctagatatt gaccaatccc atggatatga tggacaacat agtccccttt
     7981 ttcaagttca ttgtaatctt ttaatctctc tgcatttgaa acatgttgtc ttcgaaaacg
     8041 acgctttaat ttcttttgaa aaatctcatg ttcagttatc aataaaatct tttcatctac
     8101 aaaatgaaaa ccatgtctga gattaccctc tattaaattt acagattctt tacagatact
     8161 tgtcttatct ctagaatcca atttaatctg atattcctct aacatatcct ccaatgtttt
     8221 acttcccatt gaattgctag actgcagaat aatggtgtaa tccatttttt tatatcgttc
     8281 aatttcttct tttagaaaag aaaactgatt gaaaaattcc tgcataggat attgattgaa
     8341 ttgataaatt ttgtcaaatt tgagatttcc taaacccttt tgaagattag agaaaaaggt
     8401 cactggactt tgttttttat agatttgttc aatatcagaa aaatactgca tatcagaaaa
     8461 tgctttacta ttctgtaatt cttctgtaaa gtactgcgct aagtctcttt caaagacttc
     8521 atactgattc atcaattttt gataatcatc aaagaatatt ggagtatctt tttcaatata
     8581 atcaaagaca gtccatgtct tatcatagca caaagataaa aacttccgag agtctgcatg
     8641 actttgtttt tggtgaaaac ttgaaagaat ttcttctagg tatgatttca aaataggtga
     8701 taaagttttt gaaatttgtt tttctaaagc tgactgtcct cgttgataat ccttttctct
     8761 caaaagcata tcactagctg gaaagatagt gagttctgtc ttattttctt tcgataattg
     8821 tgtttctact tcaaatgacc tgataccatc aatttcatca ccaaaaaact caattcgaca
     8881 aggttctaac tgggatattt caaaaatatc taaaatatct cctcgaagac taaattcgcc
     8941 ctgagtttgt acttgagtaa cttttcgata gccattttcc tttaactgat ggataaacgc
     9001 gtgttgatca tattcttcac caactgagat ttttacaata ctatctttga atgcattggg
     9061 agacggtaaa atcaatcgac ttgctgcgat attacaaact aaaatccctt tcttagatga
     9121 atcagtcaaa aaacgcaagg cttcaacccg tgaaataatt ttttcctgtg aagacatcaa
     9181 aaactccacc ataggagcat catctaccaa aaatggatag acgagttcct cacccaagat
     9241 agaaataaga tcactaacaa gtccttctgc ttctccataa gttgacgtca ataacacaat
     9301 cctatcttct ttttctaaac tgcttgcaat tgcaagagcc ttagtagatg ttgataaacc
     9361 aagtattagt tgtcttttct tatctgttaa attttgatgc cattttttaa tctgatcatt
     9421 ttctgagaat aaatctaata aggtcaccat ttatccgtta tacctctgca ttgttttctc
     9481 aaattttttc tcttgtaaat agtagtttac agaatcgtca actttgtcaa cagactgtaa
     9541 aataccgata taatcatccc tgtcaaactt actcaaaaca tgatgaacaa ctgacatacc
     9601 atttttaggt cttccaattc caatcttaac acggttaaag acctgagttc ctatatgttg
     9661 aataatagac ttgataccat tatgaccacc tgctgagcct tttgctctta aacgaatttt
     9721 cccaacttcc atgtcaagat catcgtaaat gataagtaaa tcgtcaatat ccaaaccata
     9781 gtaagttaat aaagcatgaa ctgcttttcc actttcattc ataaaggtcg ttggtttaac
     9841 cagataaatt ttttctccat ttaggaaaaa ggatgctagg tcagcttgaa atatcttatc
     9901 gtgtgtaaaa gtgacattct gtttcttcgc tagttgatca atcaacataa aaccaacatt
     9961 gtgttttgtt tcaaaatatt tatcccctgg atttcccaag cctacaagta atttggtcat
    10021 ttatttttcc tttcaaaagc caaaagggtt ggaatttttt tccaacctaa ttgacaccat
    10081 ttattaattt ttagacatta aagcggaatt ccatgatgtc gccatcttga acgatatatt
    10141 cttttccttc ttcacgcaag cgtccagctt cttttacggc cttttcagat ccgtatttca
    10201 ctagatcttc atatgacatg gttactgcac gaataaagcc tttttcaaag tctgagtgga
    10261 taataccagc tgcttgagga gccttcatac cacgtttgaa agtccaagcg cgaacttctt
    10321 tttcaccagc tgtgaagtaa gttcccaatc caagcaagtg gtaagctgca cgcgtcaact
    10381 tatctacacc tgattctgtc aaaccaattg cttcaagaaa ctctttttta tcttcatcat
    10441 ccaattcaga aatttcttcc tcagcacgcg cagaaataac gactacttca gcattttctg
    10501 tcgctgcaaa ttcacgaatt tgtttgacat agtcgataga gtcaggttct gaaaccacat
    10561 cctcgtccac attagctaca taaagaactg gtttagtcgt caaaaggaaa agacctttga
    10621 caaccttttg ttcctcatct gtaaattcaa tggtacgagc tgatttcccg tcttctagga
    10681 ctggtttaat cttttgaaga acattgaatt ctgctactga ttctttatct ttttgcgtac
    10741 gtgccatctt ttctacacgc gcatatcgtt tgttcactga ttctaagtca gcaagaatta
    10801 attccagatt aattgtatca atatctgcaa gtggatctac aaaggcgtct tcacgtcctt
    10861 gctcgcgcat cacattttca tcatcaaaag cacgaactac gtgaacaatc gcatctactt
    10921 cacgaatatt ggccaagaat ttattcccta gcccttctcc ttttgaagct ccttttacaa
    10981 tccctgcaat atccgtaaat tcaaatgttg tgggaactgt ctttttagga gttatcattt
    11041 cagttagttt ttgtaggcgt tcatctggaa cttccaccat tccaacattt ggatcaatag
    11101 tcgcaaatgg gtagtttgct gcctctgctc ctgcttttgt aattgcatta aatagtgttg
    11161 atttaccaac gtttggcaaa ccaacgatac ctgctgtcaa agccatattt ctcattctcc
    11221 gttttcattt caatccctaa tattataaca caaaaagaga taaagtgcta accctctaac
    11281 taagggttct cagtcaataa ttttatttat ttttcgctca aaatcatatc gccccatcat
    11341 gacaacatgc tcacaattac tgcattttat tttgatatct gctcctacac gtgtaatttc
    11401 ccaacgatta gcctttttac cagtcgactt gattgtacaa gcgtgtggtt ttttcatctc
    11461 aacaaaattt ccaacttgat acatactact ctccttttct ttttcgatta tatcataaaa
    11521 gaggcgagcc aggctcaacc tctttcactt aatttgtacg aactggtgta atgagctgca
    11581 tgaagtcttc gtcagtatct gctggcacaa gagtaaatgg acgaacagct gagataaagc
    11641 taatagtcac cttttcgcta tttaaagctt taagagaatc aatcaagtaa gttgggttga
    11701 aactaatggt caaatcttca ccagtaacct gatcagtatc gatttcttcg tttactttac
    11761 caacttctgg agagtgaaca tgggcgctaa caaccccatc cttaatttca agtttcacag
    11821 taccattttg agtcgcactt gataaaagac gggcacgctc cattgactgg cgtaagttta
    11881 ccacattaaa agtaatagta gtgttaaagt ctgttggaat caagcgatct gtatcaggat
    11941 agtttccttc taggagacga gtatagaagc taatattttc gcttctaaag aggatttggt
    12001 tattggcaaa gaaaatctct acagtttcga tatcatctgt aaataccgct gaaaattcgc
    12061 gtagagaacg gctaggaatt acgacatcaa aatcatcact atttttttca agagtcaatt
    12121 ttttctggct taggcgatga gagtctgttg caactgtttt taactctttg tgttgactca
    12181 atacgaagtg gacacctgtt aaaatcggac gactctcttg tgtacttgca gcaaaggctg
    12241 tttcattaat aattttcttg agtaattttg tttcaagtat taaaggagtg cttgctgaaa
    12301 tttcttggat tcgtggatat tgttcgctat cttttccttt tagggtaatt tctgatttgc
    12361 cactggttaa aacaatttga ttttgttcaa tttctttaaa atcaagagtt acatcaggta
    12421 aactagatac tacattgata aagaaagaag cttcaagaag gatcgaacct aaagaagtaa
    12481 ttaacaaacc agcatcttca tttttttgag aaataaaatt ttcaattgaa atttgaccat
    12541 ttgaaccaat taaagtaata ccttcattgg tcacgtcaat ttttactgtt gataaaatag
    12601 gaatggcatt tttagaacta atagctctct tagtagtatt taatgcttgt agaaataaat
    12661 ttttattaat tgaaaaatga atcatggatt ctcctttatt tatttttagt attagaaaga
    12721 taatagtaat aatagagtct gtgaaatctg tggaaaacag cctttaaaca agtcatatca
    12781 agttttttag cttgtttaaa aaatgtggat aaaaaagata aaaaactaaa agttatccac
    12841 aaattatttg attttctttt tgattgattc aatttctaaa cgtaaattat cgtcttgatc
    12901 aatcaaagat tttattttgg catgggcatg aatgactgtg gtatgatctt ttcccccaaa
    12961 ttccttccca atttttggaa gactattatc tgttagttct ctagataaat acatggctac
    13021 ttgacgggcc aaaacaatat tttgaaggcg tctacttccc ttcatttctt tgatactaac
    13081 accataaaag ttaccaactt cagtttggat tttatcaatt gggatgacga gcatttggct
    13141 aacatcttgt ttgcgggctc taatggcttc tgcagcaata tcaatagtga tatccttgat
    13201 tttttttact ctggcaatta aagtgatgtc gttgatggct ccctcaagat ctcgaacatt
    13261 tgaatcaaat tgcccagcta ggtattctag agtatcactt tggaaattgt agcctaaatg
    13321 ttccgtttta ctttgtaaaa tggcaatacg tgtttcaaag tcagggggtg tgatagtttg
    13381 tgtcaatccc caactaaaac gcgtgacaag cctctcctcg agcccttcta gatgttttgg
    13441 actacgatca ctcgttagga caatctgttt ttgcttgtca tgaagggcgt taaaggtatt
    13501 gaaaaattct tcctgagttg cgactttttt tccgctgagt gactggatat catcgattaa
    13561 caaaagatca agactacgat aggtcttttt aaacttttcc atttccccaa gtcttaggtg
    13621 atcaagaaag tcattaataa agctttcggc agggatatat ttaacacgcg cattaggaat
    13681 attttttaga atttcatttc caatagcgtt taataagtga gtcttaccaa ggcctggtcc
    13741 tccatagata aaaagagggt tataggtcag agccaaatct tcagagacag ctaaagcggc
    13801 tgacacagcc caaacatttc catccccttg aataaagtta tcaaaggtat acttttcttt
    13861 taatcccgta tctgaataag gaatagatac taactttgga ctatagttat aaagagttaa
    13921 atttgtagct tcttcaactt gtgagctagt cgtatcttga ggtttggtga aaatatagtg
    13981 gggagttatt tcagcgtcat aaatttcaaa accagctact acaataatat cttttagttg
    14041 tttttcccag accatttcca tttcagagcg aggtagaaat atagtggcaa cattttcctc
    14101 taccttgatg agttcagctt gaatagcata gaaatcatac atggatcgag tcagtctttc
    14161 ttgtgcaaat tctaatatac gattccaaaa ttgtttttct ttcaatcctt tctcctcctt
    14221 tactatttaa aagtttaata ctagagatat tttaccatag atagcaagaa ttttccacaa
    14281 gctgtgaaaa ataatccaca atgttaccaa actttatcca caggttgggg ataaaagaag
    14341 aaattattga tttattaagc tttttattga aaaacatagt ggataacctt gtgagataaa
    14401 aaaataaaag aacagcctta tttcaggctg ttgataattc tactatattc ttcttgattt
    14461 gaaaaagaaa taatgatttt tccactgtct tttttagata gtttaatttc tacatctaat
    14521 ccgagtagtt ttcttaactg tttttcttca ttttgtatga aatgattagt tttttgctgt
    14581 ttcttttgtt ttttctctgt cagaagagct tctaatttcc ttacagaaat atcttcttct
    14641 ataatccgtt gaaagaaata gtcttgttgt tccttattta acccaactag ggaacgcgca
    14701 tgggcttgtg atagtttgcc attttctact tctgaaagaa tctgttctgg caaggaaagt
    14761 aaacgaatgg agttgctgat atatggacga gacttgccca tcttatctgc aatttcagca
    14821 tgggtgaatc ctttctctac gagagattca taggcgcgtg cttcttctat tgggtttaaa
    14881 ttttctctct gtaaattttc aataatggac tggaccatca tctcttggtc tgaaatctgt
    14941 ttaacaacag ctgggataga ccgtagacca gctaaaagtg aagcccgata gcgtctctct
    15001 cctgcaagga tttcataacc aataacagga gattgacgaa caataatcgg ttgaatgacc
    15061 ccattttctt tgatagactg tgctagttca tctagttttt ctctatcaaa ttcttttcgg
    15121 ggttgatagg gatttttttg tatatctgtg atagaaatca tttcaaattt ttccatgatt
    15181 ctacactaac acatcttttc tcttatgtaa agctttcttt acatagatgt caattaagat
    15241 tctaaatcac cagaactctt gttaagtttg atagaggtag tttcttcttt cccgttacga
    15301 tagtaggtta tcttaatggt gtctccgata gaatggttgt aaagagcact ttgtaagtct
    15361 gttgatgaag caatctcttt gtcatctact tttgtaatta catcgtattt ttcaaggtga
    15421 ccattggcag gcatattact ttgtaccgaa cgaacaacta caccagatgt aacattactt
    15481 ggaatattga gtcttctgat gtcgcttgta ctcacattag ataaattaac catctggatt
    15541 cccaaagctg gacgcgtcac ttttccgttt ttttctaact gttcaataat attgatagca
    15601 tcatttgcag gaattgcgaa accaagacct tctacagatg ttcctccatt tgtagcaatt
    15661 ttacttgagg taattccgat aacctgccct tgaatattga tcagtgggcc gccagagtta
    15721 cctgggttaa tagcagtatc agtttggatg gcttttgtag aaatagcttg tccatcttcc
    15781 gattttaagg atacatttct attgagactg gatacgatac cttgagtgac tgtatttgca
    15841 tattcagaac ctaacgggct accgatggca atagcagttt ctcctacagt taacttacta
    15901 gaatcaccaa actcagctac tgttgtcact ttttctgaag agatttttac gacagcaata
    15961 tcagagaaag tgtcagctcc gacaatttct ccaggtactt tagtcccatc tgacaatcga
    16021 atatctactt tgctggcgcc atttataacg tgattgttgg tgacgatgta agcttcttta
    16081 tcattctttt tataaataac tccagatcct tcactagaga ttcgctgaga atctgtgtca
    16141 gtatcatcat tgccaaatac gctattttgt ctgtttgccg aataagtaat aacagaaaca
    16201 acagcatctt ttactttgtt aacagcctgt gttgttgaat tttcgttctt ataggcagtt
    16261 tgtgtaatag tactattgtt gttagagttg tttacactac ttttttgagt tagttgagtt
    16321 attgaaaaac tacccaaggc tccactaaaa aagctaatga cgataacgac taataattga
    16381 aaccattttt tgtaaaatgt ttttagatgt ttcatatttg cctccatatg tttgaattac
    16441 tgaaagtata aactgactag cttaattata acttaaacac aaaagtttta cacaaactgt
    16501 ggataactct tttgaaactg tgattttctt aattgaaatc tattttttat tttgtgaata
    16561 agatgtgaaa aaatagagaa tatgttagaa tagagtcatg aaaattaaag ttgtaacagt
    16621 tgggaaactg aaagaaaagt atttaaaaga tggtatcgca gagtattcaa aacgaatttc
    16681 tagatttgct aagtttgaaa tgattgagtt atcagatgaa aaaacaccag ataaggccag
    16741 tgaatcagaa aatcaaaaga ttttagaaat agaaggtcag agaattttat caaaaattgc
    16801 tgaccgtgat ttcgttattg tgttagccat tgaagggaaa actttcttct cagaagaatt
    16861 tagtaagcag ttagaagaaa cttctataaa aggattttct actcttactt ttattattgg
    16921 gggaagttta ggattgtcat catctgtaaa aaatagagcc aatctttctg tcagttttgg
    16981 tcgcctaacc ttaccccatc agttaatgag actagttctt gttgaacaaa tctatcgcgc
    17041 ttttacgatt cagcagggat tcccctacca taaatagaaa attgactttt aattgaattt
    17101 ttggtagaat aattgtatta ggtctcatag ctcagctgga tagagcattc gccttctaag
    17161 cgaacggtcg caggttcgaa tcctgctggg atcaatataa tagcaaagct gggaattttc
    17221 ccggcttttt tcttaaaaaa gtacactttg ggagaaaaaa atgacagttg agagaatttt
    17281 atctaaaacg aaattccatt ttgtataatg gtttttgtaa gttagcttac aagaaaaaac
    17341 attttaggag attttattat gaaaaacaca gttaaattgg aacagtttgt agctttgaag
    17401 gaaaaagact tacaaaagat taaaggtggg gagatgaggt tgtcaaaatt cttccgtgat
    17461 tttattttac aaagaaaaaa gtaatgaaat aaggggaaag agtaatggat ttatttggat
    17521 ttgggacggt tattgttcat tttttaatta ttagtcacag ttaccatttt atttgtaaag
    17581 gtcaaataaa tagaaaagaa ttattcgttt ttggtgctta tacattacta acagaaatag
    17641 tatttgattt tcccttatat attctatatt tagatgggtt agggattgaa agatttttat
    17701 ttcctttggg attatattcc tattttcgat ggatgaaaca gtatgagagg gatagaggac
    17761 tattcctaag tttactacta tctcttttat atgagagcac tcataacttt ctgtccgtaa
    17821 ctttctcctc tataacagga gataattttg ttttacaata tcatttccca ttctttttcg
    17881 ttgtgacggt gttaacctat tttgttacat taaaaatcat ttactatttc catttggaac
    17941 tagcctattt tgacgaggac tacctttatc ctttcttgaa aaaagtattt tttgctttac
    18001 tattgctaca tattgtatct ttcgtttcag atatggtaag tacgattaaa catttgaata
    18061 gttttggaag tattttgtca tctattgtct ttatctctct ccttttgacc ttctttgcaa
    18121 tgaattctca taaagttcaa atggagaaag agattgcttt gaagcagaag aaatttgaac
    18181 agaaacattt acagaattac acagatgaaa ttgttggtct gtataatgaa atccgtggtt
    18241 ttcgacatga ttatgctgga atgcttgtca gcatgcagat ggcaattgac agtggtaatt
    18301 tacaggaaat tgacagaatt tacaatgaag ttttagtcaa agcaaatcat aaattgcgtt
    18361 cagataagta cacttacttt gatttgaaca acatagaaga ctcagcttta cgaagtttgg
    18421 ttgctcagtc aattgtctat gctcgaaata atggtgtaga gtttacactg gaagtaaaag
    18481 atacgattac caagcttcca attgaactat tggatttggt tcgtatcatg agcgttttat
    18541 tgaataatgc tgtcgaagga tcggctgata gctataaaaa gcagatggaa gtagcagtta
    18601 ttaagatgga aactgaaaca gttattgtga ttcagaattc atgtaaaatg acgatgactc
    18661 cttcaggaga tctatttgcc ttaggattct ccactaaggg aagaaatcgc ggagtcggat
    18721 taaataatgt gaaagaacta ctagataagt acaacaatat tattttagaa acagagatgg
    18781 aaggcagtac atttagacaa atcattagat ttaagaggga atttgaatga aagttttaat
    18841 tttagaagat gttattgaac atcaagtgag actagagaga atattggatg aaatttcgaa
    18901 agaatcgaat attccaatat catacaagac aacgggaaaa gtccgtgaat ttgaagaata
    18961 cattgaaaat gatgaagtaa atcagcttta tttcctagat atcgatattc atggaattga
    19021 gaaaaaggga tttgaagtgg ctcagctcat tcgtcattac aatccttacg ctattatcgt
    19081 ctttatcact agtcgatcag agtttgcgac tctaacctat aaataccagg tatcagccct
    19141 agattttgtt gataaggata tcaatgatga gatgtttaag aagagaattg agcaaaatat
    19201 cttctacacg aagagtatgt tacttgaaaa tgaagatgtt gtagattatt tcgactacaa
    19261 ttacaaggga aatgatttaa aaattcctta ccatgatatt ttgtatattg aaacaacagg
    19321 ggtctctcat aaattgcgca ttattggtaa gaattttgca aaagagtttt atggtaccat
    19381 gacagatatt caggaaaagg acaaacatac tcagcgattt tattctcctc acaagtcatt
    19441 tttggtaaat ataggcaata tcagagaaat tgatcgaaaa aacttagaaa ttgttttcta
    19501 tgaagaccat cgttgtccta tttcaagatt aaaaattaga aaattaaaag atattttaga
    19561 gaaaaaatct caaaagtgat tgacaattag caagaaattg atataatggt tatatctgct
    19621 acagatagaa ggtccgttgg tcaaggggtt aagacaccgc cttttcacgg cggtaacacg
    19681 ggttcgaatc ccgtacggac tattttatcc gccatagctc agttggtagt agcgcatgac
    19741 tgttaatcat gatgtcgtag gttcgagtcc tactggcgga gtatagataa aagggaacac
    19801 agctgtgttc ctctttttgt atcaatttgt atcaccaagc attttcataa ggaagtctgt
    19861 tatttcttga gaactttctt tttttccatg tgcaatccaa gtttggcaga caccaaaaag
    19921 tgcatgagtt agatagatgc tactatattc taattcggtg gtatttagat tcagttgcat
    19981 aaatcgcttt tgtaaatctg tactaagcat gatatgaagt ttatttcgta agaaattttg
    20041 gatttcttta gtcccatttt cagaaagaag ggcagccaga agtggttctg actctagata
    20101 ttcaaaaact tctaaaatag cgtctctttt gtgatgagca tgtttttgaa aaatatattc
    20161 aaatgtatgg aatagcttgc tttgatagtg ctcaatcata tcatacttat ccttatagtg
    20221 agtatagaag ctggaacgac taattccggc tttttctact aatttgacag tagaaatttt
    20281 atcaaatggc tgttccatca gtaattgtac catagcattt tcaatagttc gctttgtttt
    20341 taagcgtttg ttactttctt gcatatttcc tccttgtaaa caaattagac tatatgtcta
    20401 aaaatagatt ttttatcttg taatttagat tttttaatgt ataatctatt atatcaaaat
    20461 tttagacaat atgtttaaaa aaggagaaac taagtttaaa gaatggaaag caatttaaaa
    20521 aaaaccaacc tttattattg tcatgatcgg gatttctctt attccagatc tgtacaatat
    20581 catatttttg tcatcaatgt gggatccata tgggcaattg tctgacttac ctgtggcagt
    20641 tgtaaataat gataaagagg cttcctataa tggtaatact atggcaatag gaaaagacat
    20701 ggtgtccaat ttaaaagaaa ataaaacctt ggattttcat tttgtagatg aagaggaagg
    20761 aaagaaggga ttggaagatg gcgattacta tatggtagtg actttaccaa gtgatttatc
    20821 tgaaaaaaca actacattat ccaatattca atcgacagca gcttatcaat cattgacaag
    20881 tgagcaacaa actgagataa gtgattctgt atctcaaaat tcaactgata gtattcaatc
    20941 ggctcagtca attgtagctt tagtacaaga tttacaggga agtttagaaa acttacaaaa
    21001 tcaatcttct aatctttcga ctttaaaaaa tcaatctaat caagtatcac ctattacttc
    21061 tacttctttg ataggattgt caagtggatt aacagagata caaggagatg ttactagcaa
    21121 attagttcct gccagtcagt cgattgcatc aggtgtaaac gcatatacta caggtgttga
    21181 taaagtttct cagggcgcaa gtcaactaag tgaaaaaaat gccaccttga caggtagttt
    21241 gaataaacta gtttcaggct caaacacctt gacacaaaaa tcttctagat tgacagcagg
    21301 agttggttaa ttacaatcag gatctgggca attagcagac aaatccagtc agttactttc
    21361 aggtgcttct ccattagaga atagagctaa taaattggca gatggatctg ggaaactagc
    21421 agaaggtgga acaaagttaa cttctggatt ggaagattta cagacaggac ttgcttcttt
    21481 aggacaagga ctaggtaatg ctagtgatca actcaaatca gtatcaacag aatctaaaaa
    21541 tgcagagatt ttgtcaaatc cactcaatct ttcaaaaaca gacaatgatc aagttcctgt
    21601 aaatggaatc gcaatagctc cttatatgat atcagttgct cttttttttg cagcaatatc
    21661 aacaaatatg atatttgcga aattgccttc aggacgtcat ccagagagcc gttgggcttg
    21721 gttgaaatct tgagctgaaa taaatggtat tatagctgtt ttggcaggaa ttttggtata
    21781 tggaggagtt cagcttattg gtttaactgc taatcatgag atgagaatat ttattctcat
    21841 catcctaaca agtttagtat tcatgtctat ggtgaccact ttagcaacgt ggaatagccg
    21901 tataggagct tttttctcac ttattttgct tttactacag ttagcatcaa gtgcaggtac
    21961 ttatccactt gctttgacaa atgatttctt tagatctatt aatccctggt taccaatgag
    22021 ctattcagtt tcgggattac gacaaacaat ctctatcaac aagtcatttt cctagctgtc
    22081 atactagctc tatttactgg tttaggtatg ctagcctatc aacataagaa aatggaagaa
    22141 gattaaaaaa atcgaccgat taactggtcg attttttatg ccttagatga ctttcgtctg
    22201 tgattataga ttccaaatag taagagagaa gtaaaggaac agattgctcc agtaataaaa
    22261 ccattgggaa tgaaggaaag tgtaatagtt cctttcccct tgggaatgtc aactttcata
    22321 aatccagttt gagcttgttt aatttctatt ttcttaccat cttggtaggc agaccaacct
    22381 ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt ggacatcata tgtagcaaaa
    22441 accttgtttt tagaagttga tactgtgaca ggttgttctt taattttttg aattgcctcg
    22501 gtgaaagttt tggtatctaa acgatagaag gtaggagatt caaatgatac ttgtgaattt
    22561 ccagggaaac taacattgat attgaaagtt tttttctctt tagtatatcc tagattaaag
    22621 aaggagaaga cattatcagt tgtaaaagtc tttttttcac catttacaag gatgtcaacc
    22681 ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag agagataaac ttggctgttt
    22741 tctggaactt caatttgata ctggattgct gcatcttcat ttgaagaact tgtgacacta
    22801 atcaaatcat tagtattttc tattttttct gttttttcat aaggtattgg agaaaaataa
    22861 tcaaaattga cgttagcaag ttgatttaaa aatgaggcct gattatccaa ggtatgttca
    22921 ttgaacttga catcattgta aacagattga ctagcaactg caatcggaag agagtattga
    22981 ttttcatata gggtaagatt atctttttga tagatatctt taaagccata cttatcaata
    23041 ggactgtctg agatattgta ctggatacca aataaactat cagccaaaat actattattt
    23101 gcatatcgga gattgagatt agtcccagag gatttaaaac caagtttatc taaagtagag
    23161 cttgatgaac gatttcgaac agatgaaaat tgagagattc cattgtagtt gaatttcata
    23221 ctgtcatttc ctgtctgagt ttgtagtttt tcagtacgag taaattgatt tccaatatat
    23281 gttgagaaag attccatagc tgggatatct cgactataag cacttcgaga agcaaatccc
    23341 cattccttag caattccgtc catttgagat gaagcattta aactcatttc aaccagtata
    23401 aataaagaga ttagaatggc aaatagattc acagatataa actttttgat aactgcaagg
    23461 agtaaaagag aatagacaac caaaaattca agagtaagca gaatattcaa atctgttaaa
    23521 aaagaataat gcgattttag atagatggta gctaaaaatc ctgttactac aagaaaaagc
    23581 gaaactaaaa aattccagac tttaagttct ttcagacgct ttaagacttc tgctgctgtg
    23641 taaattaaca aggtagagaa aatccaagca tagcgatgta aaaacatgtt tggagtatgc
    23701 atgccttgcc aaaataagtc aagagcttct atgtaaaagc ttgcaattag aaatgcaaag
    23761 aatattatat atatgagttt cacgtgaaac ttaatagatt tcagcgtaaa aaataaaatg
    23821 gtcaaaataa agggaagtag tccaacaaaa atcattggga tggccccata ctttgttgtg
    23881 tcaaaggaac caatgaattg cttagcaaag agatcaagat accagctact ttcagtttga
    23941 aactttgtaa cttcagtcaa tttttcccca tgtgtctgta aatcaaacag agtgggaaga
    24001 gtcataatca aactagccat accagctaaa aaggagataa ctatgaaatc aagaacagat
    24061 gattttcgag tcttaaagtc ccacgaaatt tgacagagat accagaaaat aagaaacaat
    24121 actgtcatat atccaaaata ataattttga ataaataaga ttgacagact tgtaaagtac
    24181 aataggagtt tcttttcagt tatcagtaga tgtaaaccag ttataattaa aggaatcaag
    24241 ataaaaacat ctagccaggt ttttatctct aattgactga cagtgaaact catcagagca
    24301 taggaagtag ataaggctag ctttaaagtc tgagggatag attgaaacaa tttattcaaa
    24361 ctaaaaaagg ttgacagacc aatcaatcca aattttaaga gagtggtcag atagacagca
    24421 tctggcatat tcgttagatc aaaaaagtaa actagaggcg cgagaaaact acccaagtaa
    24481 taactagata gggcatagaa gtttagccct agaccacttg taaaggtgta aaacagacta
    24541 ctatttccat gtaggatatt tcgtaaggct acatcaaaaa taacgtattg atgaaagcca
    24601 tctcctaata gaggagagtt gtcgctattc cagtagatac cttgagatag atatactcca
    24661 gacataatca ctacaggaat gatgaaagaa ataaaatagg ttcgatatgt ttttaaaaat
    24721 gatttcatgt tacctcgtag aatgatagaa aactcagttg gttaacccaa ctgagttttg
    24781 aagttttatt tagtctttcc aaagttcttt aacttttgct tgtacttctg cattttctag
    24841 gaattcatcg taggtttcat cgatacggtc aatgacgcca tttttagata agacaatgat
    24901 atggttagcc aaagtttgaa taaattcgtg gtcatggcta gcaaagatga ttgattcttt
    24961 aaagtttttc aatccatcat tcaagcttga gatagattcc aagtccaagt gatttgttgg
    25021 atcatcaagt acaaggacat ttgattttaa gagcatgagt tttgaaagca tgacacgaac
    25081 tttttctccc cctgacaaga catttacagg tttgttaact tcatctccag agaagagcat
    25141 acggccgagg aaaccacgta ggaaagtatt gtcatcttct tctttacttg cgaattgacg
    25201 caaccagtca agaattgatt ctcctcctgc aaaatcagct gagttatctt ttggtaggta
    25261 agattgacta gttgtaactc cccacttgac agttccttca tagtcaatat ctcccatgat
    25321 tgcacgaatt aatgcagttg tttgaatatc attttgtcca ataagtgctg tcttatcatc
    25381 tggacgcaag atgaaactaa tattatccaa gatagtttca ccatcaatct ttacagttag
    25441 attttctact gtcaagagat cattaccaat ctcacgttcc gctttaaagt tgataaatgg
    25501 atatttacga ctagatggta caatctcttc tagctcaatc ttatcaagca ttttcttacg
    25561 tgatgttgcc tgccttgact tagaagcatt ggcagagaaa cgagcaacga attcttgcaa
    25621 ttgtttaatt ttttcttctg ctttagcatt acggtctgct agcaatttag cagcaagctc
    25681 agaagattcc ttccagaagt cgtagtttcc gacatagagt ttgatttttc caaagtcaag
    25741 gtcggccatg tgagtacaaa ctttgtttaa gaagtgacgg tcgtgggata ctacgataac
    25801 tgtgttatca aagtcaatca agaagtcttc taaccaagta atcgattgga tatccaaacc
    25861 gttagtaggc tcgtccaaga gaagaacatc tggtttacca aaaagtgctt tggcgaggag
    25921 aacctttact ttttcaccgt tggccaattc gctcatgttt tggtagtgta attcttctgg
    25981 aatgtttagg ttttgaagta gttgagaggc ttcactctct gcttcccaac ctccaagttc
    26041 ggcaaactct ccttcgagtt cggcagcacg aaccccgtcc tcgtctgaga aatcttcctt
    26101 catgtagata gcatctttct ctttcatgat gctataaagt ttttcatttc ccatgataac
    26161 gacatcaatg gcacgttcat cttcgtagtc aaagtgattt tgacgaagaa cagagagacg
    26221 ttcatctgga ccaagagaga tgtgaccagt agtaggttcg atatctccag ctaaaatttt
    26281 taaaaaggtt gattttccgg caccattagc accgattaat ccgtaagtat ttccttctgt
    26341 aaatttgata ttgacatcat caaaaagttt gcgatcacta aaacgtagtg aaacatcaga
    26401 tactgtaagc aatatttttc tcctatatgt gtaatatatt tattctacta gaaaatacag
    26461 aaatattcaa atttttattt gtcaattttg tgtaaattat atttacagta tcctttacac
    26521 aaatctgtaa aaagcaaggc tgatttattt tgataaatta cggttatttc attaaaaaaa
    26581 tgctataatt gaaaggacta tatcgaagga gaacaaaatg actaaaccca ttattttaac
    26641 aggagaccgt ccaacaggaa aattgcatat tggacattat gttggaagtc tcaaaaatcg
    26701 agtattatta caggaagagg ataagtatga tatgtttgtg ttcttggctg accaacaagc
    26761 cttgacagat catgccaaag atcctcaaac cattgtagag tctatcggaa atgtggcttt
    26821 ggattatctt gcagttggat tggatccaaa taagtcaact atttttattc aaagccagat
    26881 tccagagttg gctgagttgt ctatgtatta tatgaatcta gtttcgttag cacgtttgga
    26941 gcgaaatcca acagtcaaga cagagatttc tcagaaagga tttggagaaa gcattccgac
    27001 aggattcttg gtctatccaa tcgctcaagc agctgatatc acagctttca aggctaatta
    27061 tgttcctgtt gggacagatc agaaaccaat gattgagcaa actcgtgaaa ttgttcgttc
    27121 ttttaacaat gcatataact gtgatgtctt ggtagagccg gaaggtattt atccagaaaa
    27181 tgagagagca gggcgtttgc ctggtttaga tggaaatgct aaaatgtcta aatcactaaa
    27241 taatggtatt tatttagctg atgatgcgga tactttgcgt aaaaaagtaa tgagtatgta
    27301 tacagatcca gatcatatcc gcgttgagga tccaggtaag attgagggaa atatggtttt
    27361 ccattatcta gatgtttttg gtcgtccaga agatgctcaa gaaattgctg atatgaaaga
    27421 acgttatcaa cgaggtggtc ttggtgatgt gaagaccaag cgttatctac ttgaaatatt
    27481 agaacgtgaa ctgggtccta ttcgtgagcg ccgtattgaa tttgctaagg atatgggaga
    27541 agtttataat atgattcaaa aaggtagtga aagagcgcgt gaagttgcgg gtcaaaccct
    27601 atctgaggta aaaggggcaa tgggacttca ttactttaac taagtttatt ttacaagaaa
    27661 ctatcatttc tatctcgaag aaaagatagt tttttattta cccctgtaac atttgacaaa
    27721 tttttataga atggtatgat agatacaata taaaaagagt caagctcaaa aagaaagaaa
    27781 agaggaaact tcgaatgtct aattgggaca ctaaattttt gaaaaaaggt tttacctttg
    27841 atgatgtatt gcttattcca gctgaaagtc atgtgttgcc taacgatgca gatttaacaa
    27901 ctaaattggc agataatttg actttaaata tcccaattat taccgctgcc atggacacag
    27961 ttacagagag tcaaatggcc attgctattg ctcgtgcagg tggtctcgga gttatccata
    28021 aaaacatgtc aattgctcaa caagcagacg aggttcgtaa ggtaaaacgt tctgaaaatg
    28081 gagttattat tgatccgttc ttcttgacgc ctgaacatac aattgctgaa gcagatgagc
    28141 ttatgggtcg ttaccgcatc agtggtgttc cagttgttga aacacttgaa aatcgtaaat
    28201 tggttggtat tttgacaaac cgagatcttc gttttatttc agattataat caaccaattt
    28261 caaaccatat gactagtgaa aatcttgtta ctgctcctgt gggtacggat cttgcaacgg
    28321 ctgagagtat tcttcaagag catcgtattg aaaaacttcc gttggtcgat gaagaaggca
    28381 gtctttctgg tttgatcact atcaaagata ttgaaaaagt tattgagttt ccaaatgcgg
    28441 ctaaagatga gtttggtcgt cttctagttg caggtgcagt aggtgttact tcagatacat
    28501 ttgaacgtgc agaggctctt tttgaggcag gagcggatgc gattgttatt gatactgcac
    28561 atggtcattc tgcaggtgtc ttgcgtaaaa ttgccgagat tcgtgctcat ttcccagatc
    28621 ggactttgat tgctggaaat attgctactg ctgaaggtgc acgtgccctt tatgaagcgg
    28681 gtgtagacgt tgttaaggtt ggtattggac caggttctat ctgtactact cgtgtgattg
    28741 ctggtgttgg tgttccgcaa gtaacagcta tctacgatgc tgcagctgtt gcgcgcgaat
    28801 atggtaaaac gattattgct gacggtggga tcaagtattc tggagatatt gtaaaagcac
    28861 ttgctgcagg tggaaatgct gttatgcttg gatctatgtt tgctggaact gatgaagctc
    28921 caggcgaaac tgaaatcttc caaggacgta aattcaagac ttaccgtggt atgggatcaa
    28981 ttgctgctat gaagaaaggt tcaagcgacc gttatttcca aggttctgtc aatgaagcaa
    29041 acaagcttgt tccagaagga attgaaggtc gtgttgctta taaaggagcg gcagctgata
    29101 ttgttttcca aatgattggt ggtattcgct ctggtatggg ttactgtggt gcagctaacc
    29161 ttaaagaact acacgataat gctcaattta ttgaaatgtc tggtgctggt ttgaaagaaa
    29221 gccatcctca tgatgtgcaa attactaatg aggcaccaaa ttattctatg taaaaaacaa
    29281 tgaaaagaac tccagtgaaa acaggagttc ttttacaatg ttgtcaattt ccatttacag
    29341 cagctttacc atcctgaata gtgaagatac ttagattttc tggcagattt tgaagatggt
    29401 ctaagcttgt tgttgtgata aaggtttgga ttgattgaga aatcgtttct aataatttta
    29461 actgtctagt gttgtcaagt tcactcatca catcgtcaag cagtaatatc ggagattctg
    29521 tggtaatgct ttccattaat tcgatttctg ctaattttat cgagaggacg agactacgat
    29581 gttgaccttg gcttccgaaa ctagcatcca tcccatttat ataaaaagaa atgtcatctc
    29641 gatgaggacc gacaccagta ttctttttaa ataaatctct ggatctactt ttttctaaag
    29701 caattttgaa agattcggat aagttttgtt tgtcagttgt attgacagaa gattgatagg
    29761 atattgacaa ctcttcgatc tgattagaga gttcaaaatg tttcttacgc ccaaatgatt
    29821 ctagtttttt tatgaaatct aagcggtgat tcattacacg acatccataa tcaactagct
    29881 gatcatctaa cacagaaagg aatgtttcat ctattttttg aactgatttt aggtaagtgt
    29941 ttctttgctt taggatgtgg ttataattgg ttaagtcaga taaatagatt ggcttaattt
    30001 gcccaagctc catatcaatg aattttcgtc gaatcgaagg tgctccttta attagttgta
    30061 aatcttcagg agcaaataag acaacattca tgtgtcctac ataatctgaa aggcgtgcct
    30121 gttttaagtg attaactttt gttacacggc ctttttgtgt tagttcgatt tctaggggaa
    30181 tggatccagt ttttttctga acgagacctg aaagatgaag ttgttcctca tcaaaatgaa
    30241 tgagattttt atctgttcga gttcgatgac tacgcgttaa ggctaaaaaa tagatagcct
    30301 ctaacatgtt tgtttttcct tgtgcattac gtcccaaaaa gacattcaat ttaggattaa
    30361 agtctatttt cgtttctttg taattacgaa aagtcttgag agatagatgt tgtagccaca
    30421 tgattatcta ccagggaatc gtggagcttg ttggctttta ggtgatgaag caggtttcga
    30481 tttgtctttt ttaactccct tattcatctt tttgacaagt ttagcgatcc gttctttttc
    30541 aactttatca gcttggtatt catcttgttc ttcagaagta ggttgtgtca acaagatgtc
    30601 aatgttcatg tcagggatgt caactttatc gccaatacga agtttttttc cacgacgact
    30661 ctctaattcc ctattaaagt aaacagaatg ttcagagaga aatgatttaa tagctcctcc
    30721 gctatgtgta attccaagtt ctttgagtag tgcttggagg gtaataaatt cttcaaataa
    30781 tttgtattcc ataattcacc tcaatctttg gtattatacc atattttcct aaaaatagtg
    30841 agagagatag ctagaaatgt aagcgatttt tatttcaaaa gtgttacagg gaacaagaaa
    30901 atttcaggtt ttcgtgatat aatagaagtc tgtatataag gaggtaaatc atggagttag
    30961 tgcatggaat ttcaacacat tttatccaat caaaaaagtt taaaacaaac aaaattaccg
    31021 tgcgttttac cgctccatta tcccttgata cgattgcagg tcacatgttg agtgcaagta
    31081 tgctagagac tgctaatcag atgtacccca cttctcaaga tttgaggaga cacttggcca
    31141 gtctatacgg tacagatatg tcaaccaatt gtttcagaag agggcaaagc cacattatag
    31201 aattgacatt tacctatgtt cgtgatgagt ttttaagtag gaaaaacgtg ctaacctctc
    31261 agattttgga acttgtaaaa gaaactcttt tttcacccgc agtagttgat aatgggtttg
    31321 atccggcctt atttgaaatt gagaaaaaac aattgctagc aagtttagca gctgatatgg
    31381 atgattcttt ttattttgca cataaagaat tggataaatt gttttttcat gatgaacgtc
    31441 ttcaattgga atatagtgat ttacgaaatc gtattttagc tgaaactcca caaagttctt
    31501 attcttgttt ccaagaattt ttagccaatg atcgaataga tttctttttc ctaggtgatt
    31561 ttaatgaggt tgaaattcaa aatgtattag aatcatttgg ctttaaaggt cgaaaaggag
    31621 atgtgaaggt tcagtattgt caaccttatt ctaatatcct tcaggaaggt atggttcgga
    31681 aaaatgtggg acaatccatt ttggaattag gttatcatta ccgttctaaa tatggtgatg
    31741 aacaacattt acccatgatt gtaatgaatg gtttacttgg tggatttgct cactctaagc
    31801 tctttacaaa tgtccgtgaa aatgctggat tagcttatac catttcaagt gagcttgatt
    31861 tatttagtgg attcttgagg atgtatgctg gtatcaatcg agaaaatcgt aaccaggctc
    31921 gtaaaatgat gaataatcaa ctgcttgatt taaaaaaagg ttattttaca gagtttgagt
    31981 taaatcagac caaggaaatg attcgttggt cgttgttact ttctcaagat aatcaatctt
    32041 cattgattga acgtgcttat caaaatgcct tatttggaaa atcttcagca gactttaaag
    32101 gttggattgc aaaactcgag caagttgaca aagatgctat ttgtagagca gctaataatg
    32161 tgaaactaca ggcgatttac tttatggaag gaatagaatg acaaaggttg tttttgaaaa
    32221 aaaatactat ccagctgtaa aagaaatgat ttatcgaact cgtttggcca acggattgac
    32281 agttgctctt ttgcctaaaa aggaatttaa agaggtttac gggagtgtca ctgtacagtt
    32341 tggttcggta gatacgtttg tcacagaagt tgacggagat gtaaaacaat atcctgcagg
    32401 aattgctcat tttcttgaac ataaattatt tgagagagaa gattctagtg atttgatgtc
    32461 ggcttttacg agtctaggtg cagatagtaa tgcctttaca agctttacaa aaacaaacta
    32521 tcttttttca gcaacggatt attttttaga aaatttatat ttacttgatg aattggtaac
    32581 atcagcacac tttactgaag cttccattct gacagagcag gatattattc agcaagaacg
    32641 agaaatgtac caagatgatc cagattcgtg tttattcttt tcaactttag cgaatttgta
    32701 tcctggtaca cctttagcaa ctgatatagt tggaagtgag gagtccattt cccaaatcaa
    32761 tctaactaat ttgcaagaaa attttacaaa gttttacaaa cctgtaaaca tgtctctgtt
    32821 tttagttggt aattttgatg tggagcgagt acaggactat tttgaaagca aagaactgaa
    32881 agattcagat tttcaggaag tagcaagaga aaagttgttt ttacagcctg taaagccaac
    32941 agatagtatg agaatggaag tatcttctcc caaactagcg attggagtta gaggtaagcg
    33001 agaagtttct gaagcggatt gctatcgaca tcatatttta ttaaaattat tgtttgcaat
    33061 gatgtttagt tggacttcgg atcgttttca aaaatgttat gaatcaggta aaattgatgc
    33121 atccttatct ctggaagttg aagtaacaag tcgctttcat tttgtcatgt tgacaatgga
    33181 tacgaaagag ccagttgctt tgtctcatca atttaggaag gctattcgta attttacaaa
    33241 ggatttagat attacagagg aacatttaga tattatcaaa agagagatgt ttggcgaatt
    33301 tttcagtagc atgaactctc ttgaatttat tgcaacgcaa tatgatgctt ttgaaaatgg
    33361 tgagacaatt tttgatttgc cgaaaatttt acaggaaatt actttagagg atgtccttga
    33421 tgctggacat catttaatag atgatggtga catagttgat tttacaatat tcccatcgta
    33481 gtaacctatt ataatagaca ctagaaagaa gggatgacaa gtatgagaaa aaaaacaatt
    33541 ggagaggttt tacgattagc tagaatcaat cagggattga gtttagatga attgcagaaa
    33601 aagacagaaa tccagttaga tatgttggaa gcaatggaag cagacgattt cgatcaactt
    33661 ccaagtcctt tttacacgcg ttctttcttg aaaaaatatg catgggctgt tgagttagat
    33721 gaccaaattg ttttggatgc ttatgattct gggagtatga ttacttatga ggaagtagat
    33781 gttgatgaag atgagttgac aggtcgtaga cgttcaagta agaaaaagaa gaaaaaaaca
    33841 tcatttttac ctttatttta ttttatcctt tttgctttat cgattttaat ttttgtgact
    33901 tattatgttt ggaactatat tcaaactcaa ccagaggagc cttctctttc taattacagt
    33961 gtggttcaat caacaagttc aactagctct gttccccact cctcaagtag tagttcttct
    34021 agtatagaat cagctataag tgtatcaggc gaaggaaatc atgtagaaat cgcttataag
    34081 acaagtaagg aaacagttaa attgcaattg gcagtttcag atgttacaag ttgggtcagt
    34141 gtttcagaaa gcgaacttga gggcggtgta accttatcgc caaagaagaa aagtgcagaa
    34201 gcaacagttg caactaaaag tcctgtaaca attacgttag gtgttgtaaa aggtgttgat
    34261 ttgacagtag ataatcagac tgttgattta tcgaaattaa cagctcagac tggacaaatc
    34321 actgtaacct ttactaaaaa ttaaggaaaa acgaatgaaa aaagaacaaa ttcccaatct
    34381 cttaacaata ggtcgaattc tctttatacc tatttttatc tttattttaa cgataggaaa
    34441 ttcgatagag agtcatatag ttgcagctat tatctttgct gttgccagta ttaccgacta
    34501 tttagatgga tatttagctc gtaaatggaa tgtggtcagt aattttggta aatttgcaga
    34561 tcctatggcg gataagttac tagttatgtc ggcttttatt atgttgattg agttaggtat
    34621 ggctccggct tggattgttg cagtgattat ctgtcgtgag ttagctgtga caggtttaag
    34681 gcttttattg gttgaaactg gtggaacaat tttagcagca gcaatgcctg gaaaaattaa
    34741 aacttttagt cagatgtttg ccattatttt cttgctatta cattggactt tgcttggtca
    34801 agttctactt tatgtagcct tatttttcac tatctactct ggctatgact atttcaaggg
    34861 tagtgcctat gtatttaaag ggacatttgg ttcgaaatga aatcaataat tgatgtaaaa
    34921 aatctttctt ttcgctataa agaaaatcag aactactacg atgtgaagga tattacgttt
    34981 cacgtgaaac gtggagaatg gctttcgatt gtagggcata atggtagtgg taaatcaacg
    35041 acggttcgat taattgatgg cttactggaa gcagaatccg gagagattgt aattgatggc
    35101 caacgtttga ctgaggaaaa tgtttggaat atacgtcgtc aaatcggtat ggtttttcaa
    35161 aatccagaca atcaatttgt tggagcgact gttgaagatg atgttgcttt tggtttggaa
    35221 aatcagggac tttctcgtca agaaatgaaa aagagagtgg aagaagctct ggctttagtt
    35281 ggcatgttgg actttaaaaa gagagagcca gcgcgtctat caggtggtca aaagcaacgt
    35341 gtggccattg caggtgttgt agccctaaga ccagctattt taatcttaga tgaagcaacg
    35401 agtatgttgg atcctgaggg gcgtagagaa cttattggga cagtaaaagg aattcgaaaa
    35461 gactatgata tgacggtcat ttctattacc catgatttgg aagaagtcgc catgagtgat
    35521 cgcgtattgg tcatgaaaaa aggggaaatt gaatcaacta gtagtccaag ggagcttttc
    35581 tctcgaaatg atttagatca aattggatta gacgatcctt ttgctaatca attaaaaaaa
    35641 tctttgagcc agaatggcta tgatttacct gaaaattatt tgacagaaag tgagctagag
    35701 gataagctat gggaattgct ctagaaaatg tgaattttac atatcaagaa ggtactccct
    35761 tagcttcagc agctttgtcg gatgtttctt tgacgattga agatggctct tatacagctt
    35821 taattgggca cacaggtagt ggtaaatcaa ctattttaca actcttaaat ggtttattgg
    35881 tgccaagtca agggagtgtg agggtttttg ataccttaat cacctcgact tctaaaaata
    35941 aagatattcg tcaaattaga aaacaggttg gcttggtatt tcagtttgct gaaaatcaga
    36001 tttttgaaga aacggttttg aaggacgttg cttttggacc gcaaaatttt ggagtttctg
    36061 aagaagatgc tgtgaagact gcgcgtgaga aactggctct ggttggaatt gatgaatcac
    36121 tttttgatcg tagtccgttt gagctgtcag ggggacaaat gagacgtgtt gccattgcag
    36181 gcatacttgc catggagcca gctatattag tcttagatga gccaacagct ggtctagatc
    36241 ctctagggag aaaagagttg atgaccctgt tcaaaaaact ccaccagtca gggatgacca
    36301 tcgtcttggt aacgcatttg atggatgatg ttgctgaata tgcgaatcaa gtctatgtaa
    36361 tggaaaaggg acgtttagta aaggggggca aaccaagtga tgtctttcaa gacgttgttt
    36421 ttatggaaga agttcagttg ggagtaccta aaattacggc cttttgtaaa cgattggctg
    36481 atagaggcgt gtcatttaaa cgattaccga ttaagataga ggagttcaag gagtcgctaa
    36541 atggatagta tgattttggg gcgttatatc ccaggggatt cgattgttca ccgattggat
    36601 ccacgtagca aattgcttgc tatgatgcta ctgattttga ttgtgttttg ggctaataac
    36661 cccttgacga atctgattct ttttatagcg acagggatat ttattgcctt gtcaggagta
    36721 tctctttcat tttttattca gggcttgaag tctatgtttt tcttgattgc cttcacaact
    36781 agttttcaac tatttttcat ttctaatggg aatgttttat ttgagttttc gtttgtgaga
    36841 atcacggatt atgctttgca acaagctggg attatttttt gtcgctttgt attgattatt
    36901 ttcttttcaa ctttgttaac cttaacaacc atgcctttaa gtttggcatc agctgtcgaa
    36961 gctttattag cacctttaaa gcgtgtgaaa gttccagttc atgaaattgg attgatgctg
    37021 tctatgagtt tgcgttttgt cccaaccttg atggatgata cgacgcggat tatgaatgca
    37081 cagaaagctc gtggagtgga ttttggagaa ggaagcatcg ttcaaaaagt aaaggcgatg
    37141 attcccattt tgattcctct ttttgcgaca agtttaaaac gtgcagattc cttggctatc
    37201 gctatggaag cgcgtggcta tcagggtgga aaaggcagaa gtcaataccg acaattgaaa
    37261 tggactctaa aggatacgtt gaccattctt gttattctcg tacttggttg ttgtttattt
    37321 ttcttaaaat cttagtagct ttcaggaatt gataaaaagt tactgtaaca gtttttgata
    37381 taaaggtagg aatatgaacc gttttaaaaa atcaaaatat gtcattattg tttttgtcac
    37441 tgttctgctt gtgtcagctc tcttagcgac gacttattca agtacaattg tgacaaaatt
    37501 aggagatgga atctcattgg ttgatagagt tgtacaaaaa ccttttcagt ggtttgattc
    37561 tgtcaaatca gatttggctc atttgacacg aacatataat gaaaatgaaa gtttgaagaa
    37621 acagctttac caattagaag ttaaatcaaa tgaggtggaa agtttaaaga cagaaaatga
    37681 acaactgcgc caattgcttg atatgaagtc taaattgcaa gccacaaaga ctttagcagc
    37741 agatgttatt atgcgttctc cggtatcttg gaagcaggag ttgaccttag atgcaggtag
    37801 atcaaaaggt gcttctgaga acatgttagc tattgcaaat ggtggcttga ttgggagtgt
    37861 ttcaaaagta gaggagaact ctactatagt caaccttctg acaaatacgg aaaatgctga
    37921 taagatttct gttaaaattc aacatggctc tactacaatt tatggaatta ttattggcta
    37981 tgacaaggaa aatgacgttc ttaaaattag ccaattaaat agtaatagcg atattagtgc
    38041 gggagataag gtgactactg gtggattagg aaactttaac gttgctgata ttcctgttgg
    38101 tgaagtggtt gccacaacgc atagtacaga ctatttgaca cgagaagtaa ctgttaaatt
    38161 gagtgcagat actcataatg tagatgtgat agaattagtg gggaattcat aatgagacag
    38221 ttgaagcgag ttggagtatt tttattgctt cctttctttg ttctaattga cgcccatatt
    38281 agccagcttc tgggctcatt tttcccccat gtacatttgg ctagtcattt tctttttcta
    38341 tttctcttat ttgagacgat agaagtatca gagtatctct acctagtcta ttgttttgtt
    38401 ataggcttgg tttatgatgt ttactttttc catctaatag ggattacaac tctcttattt
    38461 atcttattgg gagccttcct tcataaattg aatagtgtta ttttgttgaa tcgttggaca
    38521 agaatgctag ctatgattgt gctgacattc ctgtttgaaa tgggtagtta tcttttggct
    38581 tttatggtag ggttgacagt agatagcatg tcgattttta tagtctatag cttggtaccg
    38641 acgatgattt taaatttttt atggattact gtttttcaat ttatttttga aaaatattat
    38701 ctataagaac gacatataaa tgtaacaaag gcgtaatatt tattaggcct ttttttggta
    38761 tactagtatt gtctttaaaa gaaggagtat ctacgtaata tgaagaaaaa aatcttagcg
    38821 tcacttttat taagtacagt aatggtttct caagtagctg ttttaacaac tgcgcatgca
    38881 gaaacgactg atgacaaaat tgctgctcaa gataataaaa ttagtaactt aacagcacaa
    38941 caacaagaag cccaaaaaca agttgaccaa attcaggagc aagtatcagc tattcaagct
    39001 gagcagtcta acttgcaagc tgaaaatgat agattacaag cagaatctaa gaaactcgag
    39061 ggtgagatta cagaactttc taaaaacatt gtttctcgta accaatcgtt ggaaaaacaa
    39121 gctcgtagtg ctcaaacaaa tggagccgta actagctata tcaataccat tgtaaactca
    39181 aaatcaatta cagaagctat ttcacgtgtt gctgcaatga gtgaaatcgt atctgcaaac
    39241 aacaaaatgt tagaacaaca aaaggcagat aaaaaagcta tttctgaaaa acaagtagca
    39301 aataatgatg ctatcaatac tgtaattgct aatcaacaaa aattggctga tgatgctcaa
    39361 gcattgacta cgaaacaggc agaactaaaa gctgctgaat taagtcttgc tgctgagaaa
    39421 gcgacagctg aaggggaaaa agcaagtcta ttagagcaaa aagcagcagc tgaggcagag
    39481 gctcgtgcag ctgcggtagc agaagcagct tataaagaaa aacgagctag ccaacaacaa
    39541 tcagtacttg cttcagcaaa cactaactta acagctcaag tgcaagcagt atctgaatct
    39601 gcagcagcac ctgtccgtgc aaaagttcgt ccaacataca gtacaaacgc ttcaagttat
    39661 ccaattggag aatgtacatg gggagtaaaa acattggcac cttgggctgg agactactgg
    39721 ggtaatggag cacagtgggc tacaagtgca gcagcagcag gtttccgtac aggttcaaca
    39781 cctcaagttg gagcaattgc atgttggaat gatggtggat atggtcacgt agcggttgtt
    39841 acagctgttg aatcaacaac acgtatccaa gtatcagaat caaattatgc aggtaatcgt
    39901 acaattggaa atcaccgtgg atggttcaat ccaacaacaa cttctgaagg ttttgttaca
    39961 tatatttatg cagattaatt tacagaggga ctcgaataga gccctctttt caggttttac
    40021 cgtgacaatc cctattaaaa attatatcaa aatagcttga aaatattgga aaagtatggt
    40081 aaaatgaaaa ttgtcgtgtg aacgataata ctcattcttg atgaattgtg aagcagttgc
    40141 ccttgggtcg ttttgcgagt tgaagtcaag aagaggaaaa aaacaaaaag gagaaatact
    40201 catggcagta atttcaatga aacaacttct tgaggctggt gtacactttg gtcaccaaac
    40261 tcgtcgctgg aatcctaaga tggctaagta catctttact gaacgtaacg gaatccacgt
    40321 tatcgacttg caacaaactg taaaatacgc tgaccaagca tacgacttca tgcgtgatgc
    40381 agcagctaac gatgcagttg tattgttcgt tggtactaag aaacaagcag ctgatgcagt
    40441 tgctgaagaa gcagtacgtt caggtcaata cttcatcaac caccgttggt tgggtggaac
    40501 tcttacaaac tggggaacaa tccaaaaacg tatcgctcgt ttgaaagaaa ttaaacgtat
    40561 ggaagaagat ggaactttcg aagttcttcc taagaaagaa gttgcacttc ttaacaaaca
    40621 acgtgcgcgt cttgaaaaat tcttgggtgg tatcgaagat atgcctcgta tcccagatgt
    40681 gatgtacgta gttgacccac ataaagagca aatcgctgtt aaagaagcta aaaaattggg
    40741 aatcccagtt gtagcgatgg ttgacaccaa tactgatcca gatgatatcg atgtaatcat
    40801 cccagctaac gatgacgcta tccgtgctgt taaattgatc acagctaaat tggctgacgc
    40861 tattatcgaa ggacgtcaag gtgaggatgc agtagcagtt gaagcagaat ttgcagcttc
    40921 agaaactcaa gcagattcaa ttgaagaaat cgttgaagtt gtagaaggtg acaacgctta
    40981 atttatacaa atagtaatta cctaggaggg cggggcttag cccggctctc ctattttcaa
    41041 aaaatatagg agaattaaaa tggcagaaat tacagctaaa cttgtaaaag agttgcgtga
    41101 aaaatctggt gccggtgtta tggacgctaa aaaagcgctt gtagaaacag acggtgacat
    41161 cgaaaaagcg attgaattgc ttcgtgaaaa aggtatggct aaggcagcta agaaagctga
    41221 ccgtgttgct gcagaaggtt tgactggtgt ttatgttaac ggtaatgttg cagcagttat
    41281 tgaagtaaac gctgaaactg acttcgttgc aaaaaacgct caattcgttg aattggtaaa
    41341 tactacagct aaagtcattg ctgaaggaaa acctgctaat aatgaagaag ctcttgcttt
    41401 gataatgcct tcaggtgaaa ctcttgaagc tgcatacgta tctgcaacag caactatcgg
    41461 agagaaaatc tcattccgtc gctttgcatt gattgaaaaa acagacgcac aacactttgg
    41521 agcataccaa cataacggtg gacgtatcgg tgttatttca gttgttgaag gtggagacga
    41581 agcacttgct aaacaattgt caatgcacat cgcagcgatg aaaccaacag ttctttctta
    41641 caaagaattg gatgagcaat tcgttaaaga tgagttggca caattgaatc acgttatcga
    41701 ccaagacaac gaaagccgtg caatggttaa taaaccagct cttccacact tgaagtatgg
    41761 atcaaaagct caattaactg atgatgttat tgctcaagct gaagctgaca tcaaagctga
    41821 attggctgca gaaggcaaac cagaaaaaat ctgggacaaa attatcccag gtaaaatgga
    41881 tcgcttcatg cttgataata ctaaagttga ccaagcttac acacttcttg cacaagttta
    41941 catcatggat gacagcaaga cagttgaagc ataccttgaa tcagttaacg cttcggtagt
    42001 tgagtttgct cgctttgaag ttggtgaagg tatcgagaaa gctgcaaacg acttcgaagc
    42061 tgaagttgca gctacaatgg cagcagcctt gaataactaa taatagaaag gaagcaattt
    42121 gcttcctttt ttgtataggg cttatatttt tcctgaaatt gtttttcccc cagtctcact
    42181 cgattagaat aattaaaaca aaaagcccta taataagggc taagtgcatt taggagacta
    42241 tacttcaaat tcatagtaag cgcgtcataa caaggtatct atcctaattc cccaacttcc
    42301 agtatactag ataaaaaata attatcggag gaaaggtatt gtactatgat gattcaacta
    42361 agtgatttag gtcaagttca cattgtttgt ggcaagacag atatgaggca gggaatagac
    42421 tcattagcct atgtagttaa aacccacttt gaattggatt ctttctccgg tcaagtcttt
    42481 ctcttttgtg gtggacgtaa agaccgcttt aaagtccttt actgggatgg tcaaggattt
    42541 tggctactat ataaacgctt tgagaacgga aaactgactt ggctaagtac agaaaaggat
    42601 gtcaaagctc tcacatctga acaagtagac tggcttatga agggcttttc tatcactccc
    42661 caaatatagt ggatttaaac tagaatagta cacctctgct tctaaaacat tgttagaaat
    42721 cgatttgact atcctgttct tatttcattt tactataaat tcatcagaaa gtcgtgattt
    42781 ctattgaaat gaggactttc tttttatact catctgtttt caaaaagcat tctagtccgt
    42841 ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtatgac atcttccaaa
    42901 gttcgaaagg ctttattctt aaatccacgt ttacgaatct ctttccacac ttgttcaatg
    42961 gggttcatct ctggtgtgta tggaggaata aatgcaaagc caatattagt cggaatcttt
    43021 aaggtacttg atttatgcca tatagcattg tccataacga gtaaaagata atcatctgga
    43081 taagcttgtg aaagctccta ttcctaaagc ccctttagcg cataactttg gctcagcttc
    43141 tattatcgct cacaccatcc atcagaagtt taatctgaag gtacccaatt atcgccaaga
    43201 agaagattgg gctaggatgg gtttaccaat cacacgtaag gaaatctcta attggcatat
    43261 caagacgagt caatactatt tggagcccct ttataacctc ttgcgagaga gactattgac
    43321 tcagccctta cttcatgcgg atgaaacttc ttatagggtg ctagagagtg atagtcagct
    43381 gacttactat tggacttttt tgtctgggaa agctgagaaa caagggatta cgctttacca
    43441 tcatgttcta atcgatttgt tcatatctta tttcaatcca ttataaatag tgagaaatat
    43501 ctatcctatc ttctagaatg tcttccaaac gtggaaactc tcgtaaacaa agaggtttta
    43561 gaggcctatt taccatggac taaagttgta caagaaaagt gcaaataaga aatctccaga
    43621 ttaggaacta tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattggac
    43681 ggttacaatt cataaagtgc tgtagagaga taacgttcac cgttatctgg tgctagggca
    43741 aggacttttt tacctgtacc taattttttg gcaacctcga tggctccgta gatagctgca
    43801 gctgaggaaa tccctacaag gaagccttct tttccaccaa tttcacgtcc gagtgcaaga
    43861 gcgtcatctg atgttacacg aacgatacca tcataggctt tagtatcaag tgtatcagga
    43921 ataaatccag ctgagatacc ttgaattttg tgaggaccag gtttttcacc agatagaata
    43981 gcagattcat ctgcttctac tgcaaaaact tgaatgttag aattttctga tttgagtgca
    44041 tgagaaacac cagaaatcgt tccaccagta cctactccag caacaaaggc atctaatcca
    44101 tctttaccga aagcagctag tatctcagct cctgttgttc tttcgtgtac ttctggatta
    44161 gctggattgt caaattgaag aggaaggaaa ccatcacgtt cagcagcgat ttcttgagcc
    44221 ttagcaatag cacctttcat tccctcgcta ccaggagtta ggacgagttc agcaccataa
    44281 gcttggataa ttttacgtcg ttctacactc atagtttcag gcataacgat gacgacttta
    44341 taccctttag cagcacctac ccatgaaagt ccaataccgg tgtttccact tgttgcttca
    44401 acaatagtag aaccaggttt cagaatacca tcttgttcag ctttttcaat catgctaagg
    44461 gcaatacggt cttttacaga tgaaccagga ttaaatgctt caagctttat atagacgtct
    44521 gcagcacctt ctggcacgat gttgttaagt ttaacaatcg gtgtttgacc gattaattca
    44581 gtaatgttgt tataaataga catatgaata cctctttgta taagatatct ttagtataac
    44641 gctatccata ccatttctat atatcataga tcaaagtcat taattttcaa gtgattgcgt
    44701 tcagctaatt ctagtaaata ggtgtgaagg aaaacgatat caggtttcgt ttgaattgct
    44761 tcattttcta gtatattttg gtacgcctct ttttattttg ctcgctaaag tagttgtgag
    44821 aatgtcaacg aaacgctgta ttattcattg tttacactaa gtttacagga acttcaacct
    44881 ctcgtaaacc ttggtcagtt aaagtgactt ttccattaaa aaactccaca agtgcagctt
    44941 taatagtttc tttttcttct ttatcaacat aaatcatcgt atcgacttga tctgtaaagt
    45001 ttgtatccag ctccatgaga ccatgttctt taaggaagtt actgtactct tggtactgag
    45061 cataagacat ttgaatagca atgccagcct gttcttttat ttcaataata ccaatttctt
    45121 tgacagctaa ggcgacactg ccggcgtaag cacgaattag tcctccagcg cctagtttaa
    45181 taccaccaaa gtagcgtgtc acgaccacac agacattggt gagattgtga ttttctagta
    45241 ccccaagcat gggaacacca gcagtaccac taggctcacc atcatcactt gtacgtttaa
    45301 tttcactacg ttctccaata atgaaggcag agcagttatg tgtcgctttg tagtgttctt
    45361 ttttgatggc agtaatgaag tcacgagcct cttcttcgct ataaacacgc ttggcatggc
    45421 agataaagcg agattttttg atttcttctt ggacttgacc gtcctcttta attgtcctaa
    45481 attccatgat ttaattgtac taaaaaatca tctaaagtgc tagtttttac gaataaagaa
    45541 gtatgaaagt aaatttagat tatctcggtc gtttatttac tgagaatgaa ttaacagaag
    45601 aagaacgtca gttggcggag aaacttccag caatgagaaa ggagaagggg aaacttttct
    45661 gtcaacgctg taatagtact attctagaag aatggtattt gcccatcggt gcttactatt
    45721 gtcgagagtg cttgctgatg aagcgagtca gaagtgatca aactttatac tattttccgc
    45781 aggaggattt tccaaagcaa gatgttctca aatggcgcgg ccaattaact ccttttcaag
    45841 agaaggtgtc agagggattg cttcaagtag tagacaagca aaagccaacc ttagttcatg
    45901 cggtaacagg agctggaaag acagaaatga tttatcaagt agtggctaaa gtgatcaatg
    45961 cgggtggtgc agtgtgtttg gctagtcctc gcatagatgt ttgtttggag ctgtacaagc
    46021 gcctgcaaca ggatttttct tgcgggatag ctttgctaca tggagaatcg gaaccttatt
    46081 ttcgaacacc actagttgtt gcaacaaccc atcagttatt gaagttttat caagcttttg
    46141 atttgctgat agtggatgaa gtagatgctt ttccttatgt tgataatccc atgctttacc
    46201 acgctgtcaa gaatagtgta aaggagaatg gattgagaat ctttttaaca gcgacttcga
    46261 ccaatgagtt agataaaaag gtccgtttag gagaactaaa aagactgaat ttaccgagac
    46321 ggtttcatgg aaatccgttg attattccaa aaccaatttg gttatcggat tttaatcgct
    46381 acttagacaa gaatcgtttg tcaccaaagt taaagtccta tattgagaag cagagaaaga
    46441 cagcttatcc gttactcatt tttgcttcag aaattaagaa aggggagcag ttagcagaaa
    46501 tcttacagga gcaatttcca aatgagaaaa ttggctttgt atcttctgta acagaggatc
    46561 gattagagca agtacaagct tttcgagatg gagaactgac aatacttatc agtacgacaa
    46621 tcttggagcg cggagttacc ttcccttgtg tggatgtttt cgtagtagag gccaatcatc
    46681 gtttgtttac caagtctagt ttgattcaga ttggtggacg agttggacga agcatggata
    46741 gaccgacagg agatttgctt ttcttccatg atgggttaaa tgcttcaatc aagaaggcga
    46801 ttaaggaaat tcagatgatg aataaggagg ctggtctatg aagtgcttgt tatgtgggca
    46861 gactatgaag actgttttaa cttttagtag tctcttactt ctgaggaatg atgactcttg
    46921 tctttgttca gactgtgatt ctacttttga aagaattggg gaagagaact gtccaaattg
    46981 tatgaaaaca gagttgtcaa caaagtgtca agattgtcaa ttttggtgta aagagggagt
    47041 tgaagtcagt catagagcga tttttactta caatcaagct atgaaggatt ttttcagtcg
    47101 gtataagttt gatggagact tcctgttaag aaaagttttc gcttcatttt taagtgagga
    47161 gttgaaaaag tacaaagagt atcaatttgt tgtaattccc ctaagtcctg atagatatgc
    47221 taacagagga tttaatcagg ttgagggctt ggtagaggca gcaggctttg agtatctaga
    47281 tttattagag aaaagagaag agagagccag ttcttctaaa aatcgttcag agcgcttggg
    47341 gacagaactt cctttcttta ttaaaagtgg agtcactatt cctaaaaaaa tcctacttat
    47401 agatgatatc tatactacag gagcaactat aaatcgtgtt aagaaactgt tggaagaagc
    47461 cggtgctaag gatgtaaaaa cattttccct tgtaagatga ggaaaaaatt tgcaaaaata
    47521 gaatgaaagc gttataataa aatcataaaa acaaaaatgt ttagaaagaa ggtactcata
    47581 tgattaaata tagtatccgt ggtgaaaacc tagaagtaac agaagcaatt cgtgattatg
    47641 tagtttctaa actcgaaaag atcgaaaagt acttccaacc agaacaagag ttggatgccc
    47701 gaattaactt aaaagtttat cgtgaaaaaa cggctaaagt ggaagtaacg attccgcttg
    47761 gatctattac tctccgcgca gaagatgtat ctcaagatat gtatggttca attgaccttg
    47821 taactgataa aattgaacgt cagattcgta aaaataaaac aaaaatcgag cgtaaaaata
    47881 aaaataaggt agcaactggt caattattta cagatgcttt ggtggaagat tcaaatattg
    47941 tccagtctaa agttgttcgt tcaaaacaaa ttgatttaaa accaatggat ttggaagaag
    48001 caattctaca aatggattta ttggggcatg atttctttat ctatgtggat gttgaagatc
    48061 agacaaccaa tgtgatttat cgtcgtgagg atggcgaaat tggtttgtta gaggttaaag
    48121 aatcttaatt tcaatatgtg taaaggtagg tttactgaat tgtaaactac ctttttctta
    48181 taattgatag aattactgat tacactttta aaaagtcgct ttttgagggg tattatggta
    48241 taatgggtgc caagaggttt tgaatgaaaa aattttatgt aagtccaatt tttcctattc
    48301 tagtaggatt gattgcgttt ggagtcttat ccactttcat tatttttgtt aataataatc
    48361 tgttgacggt tttaattttg tttctttttg taggaggcta tgttttttta tttaagaaac
    48421 tgagagtgca ttatacaagg agtgatgtag aacagataca gtatgtaaac caccaagcgg
    48481 aagaaagttt gacagctcta ttggaacaga tgcctgtagg tgttatgaaa ttgaatttat
    48541 cttctggaga ggttgagtgg tttaatccct atgctgaatt gattttgacc aaggaagatg
    48601 gtgattttga tttagaagct gttcaaacga ttatcaaggc ttcagtagga aatccgtcta
    48661 cttatgccaa gcttggtgag aagcgttatg ctgttcatat ggatgcttct tccggtgttt
    48721 tgtattttgt agatgtatcc agggaacaag ccataacaga tgaattggta acaagtagac
    48781 cagtgattgg gattgtctct gtggataatt atgatgattt ggaggatgaa acttctgagt
    48841 cagatattag tcaaatcaat agttttgtag ctaattttat atcagagttt tcagaaaaac
    48901 acatgatgtt ttctcgtcgg gtaagtatgg atcgatttta tctatttact gactacacgg
    48961 tgcttgaggg cttgatgaat gataaatttt ctgttattga tgctttcaga gaagagtcga
    49021 aacagagaca gttgcccttg accttaagta tgggattttc ttatggcgat ggaaatcatg
    49081 atgagatagg gaaagttgct ttgctcaatt tgaacttggc tgaagtacgt ggtggcgacc
    49141 aggtggttgt taaggaaaac gacgaaacga aaaatccagt ttattttggt ggtgggtctg
    49201 ctgcttcaat caagcgtaca cggactcgta cgcgcgctat gatgacagct atttcagata
    49261 agattcggag tgtagatcag gtttttgtag tcggtcacaa aaatttagac atggatgctt
    49321 tgggctctgc tgtaggtatg cagttgttcg ccagcaatgt gattgaaaat agctatgctc
    49381 tttatgatga agaacaaatg tctccagata ttgaacgagc tgtttcattc atagaaaaag
    49441 aaggagttac gaagttgttg tctgttaagg atgcaatggg gatggtgacc aatcgttctt
    49501 tgttgattct tgtagaccat tcaaagacag ccttaacatt atcaaaagaa ttttatgatt
    49561 tatttaccca aaccattgtt attgaccacc atagaaggga tcaggatttt ccagataatg
    49621 cggttattac ttatatcgaa agtggtgcaa gtagtgccag tgagttggta acggaattga
    49681 ttcagttcca gaattctaag aaaaatcgtt tgagtcgtat gcaagcaagt gttttgatgg
    49741 ctggtatgat gttggatact aaaaatttca cctcgcgagt aactagtcgg acatttgatg
    49801 ttgctagcta tctcagaacg cgcggaagtg atagtattgc tatccaggaa atcgctgcga
    49861 cagattttga agaatatcgt gaggtcaatg aacttatttt acaggggcgt aaattaggtt
    49921 cagatgtact aatagcagag gctaaggaca cgaaatgcta tgatacagtt gttattagta
    49981 aggcagcaga tgccatgtta gccatgtcag gtattgaagc gagttttgtt cttgcgaaga
    50041 atacacaagg atttatctct atctcagctc gaagtcgtag taaactgaat gtacaacgga
    50101 ttatggaaga gttaggcggt ggaggccact ttaatttggc agcagctcaa attaaagatg
    50161 taaccttgtc agaagcaggt gaaaaactga cagaaattgt attaaatgaa ataaaggaaa
    50221 aggagaaaga agaatgaaag taatcttttt agcagatgtt aaaggaaaag gtaaaaaagg
    50281 cgaaattaag gaagtaccaa cagggtatgc gcaaaacttt cttatcaaaa agaatctagc
    50341 caaagaagcg actgctcaag ctgtaggtga acttcgtggt aaacaaaaat cggaagaaaa
    50401 agctcacgct gagatgattg cagaagggaa agcaattaaa gcacaacttg aagcagaaga
    50461 aactgttgta gaatttgttg aaaaagttgg tccagatggt cgtacctttg gttctattac
    50521 caataagaag attgcagaag aattacaaaa gcaatttgga attaagattg ataaacgtca
    50581 tattcaagta caagctccga ttcgagcggt tggtttgatt gatgtgccag tgaaaatcta
    50641 tcaagatatc acaagtgtaa tcaatcttcg tgtgaaagaa ggataagttt acaccttctt
    50701 gacaagattg taaaaggaag ggaagtctga tggcagaagt agaagagtta cgagtacaac
    50761 ctcaagatat cttagctgag caatccgttt taggggctat ctttattgat gagagtaaac
    50821 ttgtttttgt gcgagaatac attgagtctc gggacttttt taagtatgcc catcgtttga
    50881 ttttccaagc catggtcgat ttatccgatc gtggtgatgc catagatgca acaacggttc
    50941 gtactatcct tgataatcaa ggtgatttac agaatattgg tggcttgtct tacttggttg
    51001 agattgtcaa ttctgtgcca acttctgcta atgcggagta ttatgctaag attgttgcag
    51061 aaaaagcaat gctacgtcgt ttaattgcca agttgacaga gtctgtcaac caagcttacg
    51121 aagcgtcaca accagctgat gaaattattg ctcaggcaga aaaagggctg attgatgtca
    51181 gtgaaaatgc aaatcgaagc gggtttaaga acattcgaga tgtgttgaat ctcaactttg
    51241 gaaatctgga agctcgctcg caacaaacga ccgatattac aggtattgcg acaggttatc
    51301 gtgatttgga tcatatgaca acaggacttc atgaggagga gttgattatc ttagcagctc
    51361 gtccagcagt tggtaagaca gcatttgcct tgaatatcgc tcagaatatt gggactaagt
    51421 tggacaaaac ggttgctatt ttttcactcg aaatgggtgc ggaaagcttg gtagaccgta
    51481 tgttagctgc agaaggcttg gtggagtcac attctatccg tacagggcaa ttgacagatg
    51541 aggagtggca aaaatatact attgctcagg gtaatctagc taacgccagt atctatatcg
    51601 atgatacgcc aggtattcgg attacagaga ttcgttctcg ttctcgtaaa ttggctcaag
    51661 aaactggaaa tcttggtttg attttgatag actatttgca acttatcacg ggaactggtc
    51721 gagaaaatcg tcaacaagaa gtttctgaaa tttctcgtca gttgaaaata ctagccaagg
    51781 aattgaaggt tccagtaatc gctctgagtc agctttctcg tggtgtagaa caacgtcagg
    51841 acaagagacc ggtcttgtct gatattcgtg aatctgggtc tattgagcag gacgctgata
    51901 tcgtagcttt tctctatcgc gatgactact atgaacgtgg tggtgaagaa gaggagggta
    51961 tcccaaataa taaggtggaa gttattatcg agaaaaaccg tagtggagct cgtggaacag
    52021 tggaattgat tttccaaaaa gaatacaata aattttcaag tatctcaaag agggaggcat
    52081 aagatgtcag atgcatttac agatgtagcc aagatgaaaa aaatcaaaga agaaatcaag
    52141 gcacatgagg gacaagtcgt agaaatgact ttggagaatg gtcgtaagcg ccaaaaaaat
    52201 agattgggta agctaattga agtttatcca tccctattta ttgtggagtt tggggatgtg
    52261 gaaggagata aacaagttaa tgtttacgtt gaatccttta cttactcaga tattcttaca
    52321 gaaaagaatt tgattcatta tcttgactaa agtgagaaat tttctcactt tttctttttt
    52381 ctccgaataa tttaggtgaa ggcaatcatc gctttatatt attttttaag gaggaagaat
    52441 gaaaatttta ccgtttatag caagaggaac aagttattac ttgaagatgt cagttaaaaa
    52501 gcttgttcct tttttagtag taggattgat gctagcagct ggtgatagtg tctatgccta
    52561 ttccggagga aatggatcga ttgcgcgtgg ggatgattat cctgcttatt ataaaaatgg
    52621 gagccaggag attgatcagt ggcgcatgta ttctcgtcag tgtacttctt ttgtagcctt
    52681 tcgtttgagt aatgtcaatg gttttgaaat tccggcagct tatggaaatg cgaatgaatg
    52741 gggacatcgt gctcgtcggg aaggttatcg tgtagataat acaccgacga ttggttccat
    52801 tacttggtct actgcaggaa cttatggtca tgttgcctgg gtgtcaaatg taatgggaga
    52861 tcagattgag attgaggaat ataactatgg ttatacagaa tcctataata aacgaattat
    52921 aaaagcaaac acgatgacag gatttattca ttttaaagat ttggatggtg gcagtgttgg
    52981 gaatagtcaa tcctcaactt caacaggcga aactcattat tttatgacca agtctgctat
    53041 taaaactgaa cccctagtta gtgcaactgt gattgattac tattatcctg gagagaaggt
    53101 tcattatgat caaattctcg aaaaagacgg ctacaagtgg ttgagttata ctgcctataa
    53161 tggaagctat cgttatgttc aattggaggc tgtgaataaa aatcctctag gtaattctgt
    53221 tctttcttca acaggtggaa ctcattattt taagaccaag tctgctatca aaactgaacc
    53281 cctagttagt gcaactgtga ttgattacta ttatcctggg gagaaggttc attatgatca
    53341 gatacttgaa aaagacggct acaagtggtt gagttatacg gcttataacg gaagtcgtcg
    53401 ctatatacag ctagagggag tgacttcttc acaaaattat cagaatcaat caggaaatat
    53461 ctctagctat ggatccaata atagttcaac tgtcggttgg aagaaaataa atggtagttg
    53521 gtatcatttc aaatcaaatg gttctaaatc aacaggatgg ctgaaagatg gttctagctg
    53581 gtattatttg aaattatctg gtgaaatgca gacaggatgg ttaaaggaga atggttcgtg
    53641 gtattatctg ggtagttcag gggcaatgaa aacaggctgg taccaggtct ctggtaagtg
    53701 gtattattct tactcttcag gcgccttagc tgttaatacg acggtggatg gctacagagt
    53761 aaacagtgat ggagaacgag tatagaaaat tggagtagga gaaatttcct gctcttttct
    53821 gtaagcagtt tccttgacat ttttcttatt ttgcgctatc atatatacat ataatatatg
    53881 ggagtctgtg tacagtctga gaggaagtgt taaacttcga ccgcacctga tctgggtaat
    53941 gccagcggag ggaacgatac ttagtctaat tttgcacctt ttccatgtat ggtaaaggtt
    54001 tttctttttt ttaaaaggaa aacgagaaga ggaggttctt atgaaagcaa gcattgcctt
    54061 gcaagtttta cccctagtac aggggattga tcggatagct gttattgatc aggtcattgc
    54121 ttatctgcaa actcaagaag tgccgatggt agtgacacca tttgaaacgg tcttggaagg
    54181 ggagtttgat gagcttatgc gcattctaaa agaagcgctg gaagtggcag ggcaggaggc
    54241 agacaatgtc tttgccaatg tcaaaataaa tgtaggagag attttaagta ttgatgagaa
    54301 acttgagaag tatactgaga cgacacatta gtctattggg ctttctcgga gtcttgtcaa
    54361 tctggcagtt agcaggtttt cttaaactgc tccccaagtt tatcctgccg acacctcttg
    54421 aaattctcca gccctttgtt cgtgacagag aatttctctg gcaccatagc tgggcgacct
    54481 tgagagtggc tttactgggg ctgattttgg gagttttgat tgcctgtctt atggctgtac
    54541 tcatggatag tttgacttgg ctcaatgacc tgatttaccc tatgatggtg gtcattcaga
    54601 ccattccgac cattgccata gctcctatcc tggtcttgtg gctaggttat gggattttgc
    54661 ccaagattgt cttgattatc ttaacgacaa cctttcccat catcgtcagc attttggacg
    54721 gttttaggca ttgcgacaag gatatgctga ccttgtttag tctgatgcgg gccaagcctt
    54781 ggcaaatcct gtggcatttt aaaattccag tcagcctgcc ctacttttat gctggtctga
    54841 gggtcagtgt ctcctacgct tttatcacaa cagtggtatc tgagtggttg ggaggctttg
    54901 aggggcttgg tgtttatatg attcagtcca agaaattgtt tcagtatgat accatgttcg
    54961 ctattattat tctggtatcg attatcagcc ttttgggtat gaagttggtc gatattagtg
    55021 aaaaatatgt tattaaatgg aaacgttcgt agaattagaa tgtttctgaa aaagaaaaga
    55081 ggaaatcaaa atgaagaaaa catggaaagt gtttttaacg cttgtaacag ctcttgtagc
    55141 tgttgtgctt gtggcctgtg gtcaaggaac tgcttctaaa gacaacaaag aggcagaact
    55201 taagaaggtt gactttatcc tagactggac accaaatacc aaccacacag ggctttatgt
    55261 tgccaaggaa aaaggttatt tcaaagaagc tggagtggat gttgatttga aattgccacc
    55321 agaagaaagt tcttctgact tggttatcaa cggaaaggca ccatttgcag tgtatttcca
    55381 agactacatg gctaagaaat tggaaaaagg agcaggaatc actgccgttg cagctattgt
    55441 tgaacacaat acatcaggaa tcatctctcg taaatctgat aatgtaagca gtccaaaaga
    55501 cttggttggt aagaaatatg ggacatggaa tgacccaact gaacttgcta tgttgaaaac
    55561 cttggtagaa tctcaaggtg gagactttga gaaggttgaa aaagtaccaa ataacgactc
    55621 aaactcaatc acaccgattg ccaatggcgt ctttgatact gcttggattt actacggttg
    55681 ggatggtatc cttgctaaat ctcaaggtgt agatgctaac ttcatgtact tgaaagacta
    55741 tgtcaaggag tttgactact attcaccagt tatcatcgca aataacgact atctgaaaga
    55801 taacaaagaa gaagctagca aagtcatcca agccatcaaa aaaggctacc aatatgccat
    55861 ggaacatcca gaagaagctg cagatattct catcaagaat gcacctgaac tcaaggaaaa
    55921 acgtgacttt gtcatcgaat ctcaaaaata cttgtcaaaa gaatacgcaa gcgacaagga
    55981 aaaatggggt caatttgacg cagctcgctg gaatgctttc tacaaatggg ataaagaaaa
    56041 tggtatcctt aaagaagact tgacagacaa aggcttcacc aacgaatttg tgaaataatg
    56101 acagaaatta gactagagca cgtcagttat gcctatggtc aggagaggat tttagaggat
    56161 atcaacctac aggtgacttc aggcgaagtg gtttccatcc taggcccaag tggtgttgga
    56221 aagaccaccc tctttaatct aatcgctggg attttagaag ttcagtcagg gagaattgtc
    56281 cttgatggtg aagaaaatcc caaggggcgc gtgagttata tgttgcaaaa ggatctgctc
    56341 ttggagcaca agacggtgct tggaaatatc attctgcccc tcttgattca aaaggtggat
    56401 aaggcagaag ctatttcccg agcggataaa attcttgcga ccttccagct gacagctgta
    56461 agagacaagt atcctcatga acttagcggt gggatgcgcc agcgtgtagc cttactccgg
    56521 acctaccttt ttgggcacaa gctctttctc ttagatgagg cctttagcgc cttggatgag
    56581 atgacaaaga tggaactcca cgcttggtat cttgagattc acaaacagtt gcagctaaca
    56641 accctgatca tcacgcatag tattgaggag gccctcaatc tcagcgaccg catctatatc
    56701 ttgaaaaatc gccctgggca gattgtttca gaaattaaac tagattggtc tgaagatgag
    56761 gacaaggaag tccaaaagat tgcctacaaa cgtcaaatct tggcagaatt aggcttagat
    56821 aagtagaaaa atagggagtt ggtgaagatt atcctttacc agcgcccttt ttcttttaaa
    56881 aatgagaaaa tttcggtata atagtcaaac aaggtcaagg tttaaagaga gaggtgggtt
    56941 tgttatgaga tttaaaaata catcggatca tattgaggcc tacatcaagg cgattttaga
    57001 tcaatctggt atcgtggagt tgcaacggag tcagttggca gatacctttc aggttgttcc
    57061 tagtcagatt aactacgtga tcaagacacg ctttacggaa agtagaggct acttggttga
    57121 aagtaagcgt ggtggtggag gctacattcg tataggacga attgagtttt ctagtcatca
    57181 tgaaatgctc cgggagctgc tttactcgat tggtgagcga gtcagtcaag aaatttatga
    57241 ggatattctc cagcttttgg ttgagcagga attgatgacc aagcaggaga tgaatttgct
    57301 agaatcagta gctttggatc gcgttttagg agaagaagct ccagttgttc gagcaaacat
    57361 gctacgtcag atcatacaag aggtagatag aaaagggaag taagatgaac tattcaaaag
    57421 cattgaatga atgtatcgaa agtgcctaca tggttgctgg acattttgga gctcgttatc
    57481 tagagtcttg gcacttgttg attgccatgt ctaatcacag ttatagtgta gcaggggcaa
    57541 ctttaaatga ttatccgtat gagatggacc gtttagaaga agtggctttg gaactgactg
    57601 aaacggacta tagccaggat gaaaccttta cggaattgcc gttctcccgt cgtttgcagg
    57661 ttctttttga cgaagcagag tatgtagcgt cagtggtcta tgctaaggtg ctagggacag
    57721 agcacgtcct ctatgcgatt ttgcatgatg gcaatgcctt ggcgactcgt atcttggaga
    57781 gggctggttt ttcttatgaa gacaagaaag atcaggtcaa gattgctgct cttcgtcgaa
    57841 atttagaaga acgggcaggc tggactcgtg aagatctcaa ggctttacgc caacgccatc
    57901 gtacagtagc tgacaagcaa aattctatgg ccaatatgat gggcatgccg cagactccta
    57961 gtggtggtct cgaggactat acgcatgatt tgacagagca agcgcgttct ggcaagttag
    58021 aaccagtcat cggtcgggac aaggaaatct cacgtatgat tcaaatcttg agccggaaga
    58081 ctaagaacaa ccctgtcttg gttggggatg ctggtgtcgg gaaaacagct ctggcgcttg
    58141 gtcttgccca gcgtattgct agtggtgacg tgcctgcgga aatggctaag atgcgcgtgt
    58201 tagaacttga tttgatgaat gtcgttgcag ggacacgctt ccgtggtgac tttgaagaac
    58261 gcatgaataa tatcatcaag gatattgaag aagatggcca agtcatcctc tttatcgatg
    58321 aactccacac catcatgggt tctggtagcg ggattgattc gactctggat gcggccaata
    58381 tcttgaaacc agccttggcg cgtggaactt tgagaacggt tggtgccact actcaggaag
    58441 aatatcaaaa acatatcgaa aaagatgcgg cactttctcg tcgtttcgct aaagtgacga
    58501 ttgaagaacc aagtgtggca gatagtatga ctattttaca aggtttgaag gcgacttatg
    58561 agaaacatca ccgtgtacaa atcacagatg aagcggttga aacagcggtt aagatggctc
    58621 atcgttattt aaccagtcgt cacttgccag actctgctat cgacctcttg gacgaagcag
    58681 cagcaacagt gcaaaataag gcaaagcatg taaaagcaga cgattcagat ttgagtccag
    58741 ctgacaaggc cctgatggat ggcaagtgga aacaggcagc ccagctaatc gcaaaagaag
    58801 aggaagtacc tgtctacaaa gacttggtga cagagtctga tattttgacc accttgagtc
    58861 gcttgtcagg aatcccagtt caaaagctga ctcagactga cgctaagaaa tatctaaatc
    58921 ttgaagcaga actccataaa cgggttatcg gtcaagatca agctgtttca agtattagtc
    58981 gtgcgattcg ccgtaatcag tcaggaattc gcagtcacaa gcgtccgatc ggttccttta
    59041 tgttcctagg acccacaggt gtcggtaaga ccgagttggc caaggctttg gcagaagttc
    59101 tctttgatga cgaatcagcc cttatccgct ttgatatgag tgagtatatg gagaaattcg
    59161 cagccagccg tctaaatgga gctcctccag gctatgtggg ttacgaagaa ggtggggagt
    59221 tgacagagaa ggttcgcaat aaaccctatt ccgttctcct ctttgatgag gtagagaagg
    59281 ctcacccaga tatctttaat gttctcttgc aggttctgga tgacggtgtc ttgacagata
    59341 gcaagggacg caaggtcgat ttttcaaata ccattatcat tatgacatcg aacctaggtg
    59401 cgactgccct tcgtgatgat aagactgttg gttttggggc taaggatatt cgttttgacc
    59461 aggaaaatat ggaaaaacgc atgtttgaag aactgaaaaa agcttataga ccggaattca
    59521 tcaaccgtat tgatgagaag gtggtcttcc atagcctatc tagtgaccat atgcaggaag
    59581 tggtgaagat tatggtcaag cctttagtgg caagtttggc tgaaaaaggc attgacttga
    59641 aattacaagc ttcagctctg aaattgttag caaatcaagg atatgaccca gagatgggag
    59701 ctcgcccact tcgcagaacc ctgcaaacag aagtggagga caagttggca gaacttcttc
    59761 ttaagggaga tttagtggca ggcagcacac ttaagattgg tgtcaaagca ggccagttaa
    59821 aatttgatat tgcataaaag aataaaagta tcagcatctg accataagtc acagtggagt
    59881 gaaactcaat gaaaatcaaa ga
//
LOCUS       DBEJNA010000009        56756 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEJNA010000009 DBEJNA010000000
VERSION     DBEJNA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.09"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(74..1963)
                     /locus_tag="ACL3JB_000617"
     CDS             complement(74..1963)
                     /locus_tag="ACL3JB_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0685404.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2101..3666
                     /locus_tag="ACL3JB_000618"
     CDS             2101..3666
                     /locus_tag="ACL3JB_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0685405.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3666..4430
                     /locus_tag="ACL3JB_000619"
     CDS             3666..4430
                     /locus_tag="ACL3JB_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0685406.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4629..4844)
                     /locus_tag="ACL3JB_000620"
     CDS             complement(4629..4844)
                     /locus_tag="ACL3JB_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685407.1"
                     /translation="MAKTNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5714..6964)
                     /gene="ilvA"
                     /locus_tag="ACL3JB_000621"
     CDS             complement(5714..6964)
                     /gene="ilvA"
                     /locus_tag="ACL3JB_000621"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0685408.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7014..7370)
                     /locus_tag="ACL3JB_000622"
     CDS             complement(7014..7370)
                     /locus_tag="ACL3JB_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0685409.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7608..7844)
                     /locus_tag="ACL3JB_000623"
     CDS             complement(7608..7844)
                     /locus_tag="ACL3JB_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685410.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(7951..8973)
                     /gene="ilvC"
                     /locus_tag="ACL3JB_000624"
     CDS             complement(7951..8973)
                     /gene="ilvC"
                     /locus_tag="ACL3JB_000624"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0685411.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9039..9515)
                     /gene="ilvN"
                     /locus_tag="ACL3JB_000625"
     CDS             complement(9039..9515)
                     /gene="ilvN"
                     /locus_tag="ACL3JB_000625"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0685412.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9508..11208)
                     /locus_tag="ACL3JB_000626"
     CDS             complement(9508..11208)
                     /locus_tag="ACL3JB_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0685413.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11408..13075)
                     /locus_tag="ACL3JB_000627"
     CDS             complement(11408..13075)
                     /locus_tag="ACL3JB_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0685414.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13078..13443)
                     /locus_tag="ACL3JB_000628"
     CDS             complement(13078..13443)
                     /locus_tag="ACL3JB_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0685415.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13600..13788)
                     /gene="rpmB"
                     /locus_tag="ACL3JB_000629"
     CDS             complement(13600..13788)
                     /gene="rpmB"
                     /locus_tag="ACL3JB_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0685416.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSCKVERV"
     gene            complement(13907..14341)
                     /locus_tag="ACL3JB_000630"
                     /pseudo
     CDS             complement(13907..14341)
                     /locus_tag="ACL3JB_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163337.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(14817..16361)
                     /locus_tag="ACL3JB_000631"
     CDS             complement(14817..16361)
                     /locus_tag="ACL3JB_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0685417.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16574..16876
                     /gene="gatC"
                     /locus_tag="ACL3JB_000632"
     CDS             16574..16876
                     /gene="gatC"
                     /locus_tag="ACL3JB_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0685418.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDHLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            16876..18342
                     /gene="gatA"
                     /locus_tag="ACL3JB_000633"
     CDS             16876..18342
                     /gene="gatA"
                     /locus_tag="ACL3JB_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0685419.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18342..19784
                     /gene="gatB"
                     /locus_tag="ACL3JB_000634"
     CDS             18342..19784
                     /gene="gatB"
                     /locus_tag="ACL3JB_000634"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0685420.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19908..20951
                     /locus_tag="ACL3JB_000635"
     CDS             19908..20951
                     /locus_tag="ACL3JB_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HGR0685421.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            complement(20976..21206)
                     /locus_tag="ACL3JB_000636"
     CDS             complement(20976..21206)
                     /locus_tag="ACL3JB_000636"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685422.1"
                     /translation="MVNVKEYPLYFFSYSMEIKEQTRKLAASCSKHCFEVVDRTDEVS
                     NHIYGNVTLTWSEEIFEEYYISKGRSKFTPTC"
     gene            21329..21889
                     /gene="efp"
                     /locus_tag="ACL3JB_000637"
     CDS             21329..21889
                     /gene="efp"
                     /locus_tag="ACL3JB_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0685423.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21911..22300
                     /locus_tag="ACL3JB_000638"
     CDS             21911..22300
                     /locus_tag="ACL3JB_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0685424.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            22293..22715
                     /gene="nusB"
                     /locus_tag="ACL3JB_000639"
     CDS             22293..22715
                     /gene="nusB"
                     /locus_tag="ACL3JB_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0685425.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFVYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22764..22958)
                     /locus_tag="ACL3JB_000640"
     CDS             complement(22764..22958)
                     /locus_tag="ACL3JB_000640"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0685426.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFFNFL
                     NHAKPIWIFVYNYIYYHFFR"
     gene            complement(23013..23488)
                     /locus_tag="ACL3JB_000641"
                     /pseudo
     CDS             complement(23013..23488)
                     /locus_tag="ACL3JB_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(23506..23691)
                     /gene="briC"
                     /locus_tag="ACL3JB_000642"
     CDS             complement(23506..23691)
                     /gene="briC"
                     /locus_tag="ACL3JB_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR0685427.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(23954..24721)
                     /locus_tag="ACL3JB_000643"
     CDS             complement(23954..24721)
                     /locus_tag="ACL3JB_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0685428.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(24718..25584)
                     /gene="accD"
                     /locus_tag="ACL3JB_000644"
     CDS             complement(24718..25584)
                     /gene="accD"
                     /locus_tag="ACL3JB_000644"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0685429.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(25621..26988)
                     /gene="accC"
                     /locus_tag="ACL3JB_000645"
     CDS             complement(25621..26988)
                     /gene="accC"
                     /locus_tag="ACL3JB_000645"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0685430.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(27000..27422)
                     /gene="fabZ"
                     /locus_tag="ACL3JB_000646"
     CDS             complement(27000..27422)
                     /gene="fabZ"
                     /locus_tag="ACL3JB_000646"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0685431.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(27419..27904)
                     /gene="accB"
                     /locus_tag="ACL3JB_000647"
     CDS             complement(27419..27904)
                     /gene="accB"
                     /locus_tag="ACL3JB_000647"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0685432.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27907..29142)
                     /gene="fabF"
                     /locus_tag="ACL3JB_000648"
     CDS             complement(27907..29142)
                     /gene="fabF"
                     /locus_tag="ACL3JB_000648"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0685433.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(29164..29895)
                     /gene="fabG"
                     /locus_tag="ACL3JB_000649"
     CDS             complement(29164..29895)
                     /gene="fabG"
                     /locus_tag="ACL3JB_000649"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0685434.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQVGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29929..30849)
                     /gene="fabD"
                     /locus_tag="ACL3JB_000650"
     CDS             complement(29929..30849)
                     /gene="fabD"
                     /locus_tag="ACL3JB_000650"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0685435.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30842..31816)
                     /gene="fabK"
                     /locus_tag="ACL3JB_000651"
     CDS             complement(30842..31816)
                     /gene="fabK"
                     /locus_tag="ACL3JB_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0685436.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31935..32159)
                     /locus_tag="ACL3JB_000652"
     CDS             complement(31935..32159)
                     /locus_tag="ACL3JB_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0685437.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(32219..33193)
                     /locus_tag="ACL3JB_000653"
     CDS             complement(32219..33193)
                     /locus_tag="ACL3JB_000653"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0685438.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(33193..33627)
                     /locus_tag="ACL3JB_000654"
     CDS             complement(33193..33627)
                     /locus_tag="ACL3JB_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0685439.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(33721..34506)
                     /locus_tag="ACL3JB_000655"
     CDS             complement(33721..34506)
                     /locus_tag="ACL3JB_000655"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0685440.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRVSSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34875..36239
                     /locus_tag="ACL3JB_000656"
     CDS             34875..36239
                     /locus_tag="ACL3JB_000656"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0685441.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            36242..36613
                     /locus_tag="ACL3JB_000657"
     CDS             36242..36613
                     /locus_tag="ACL3JB_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0685442.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36826..38100
                     /gene="serS"
                     /locus_tag="ACL3JB_000658"
     CDS             36826..38100
                     /gene="serS"
                     /locus_tag="ACL3JB_000658"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0685443.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(38125..39024)
                     /locus_tag="ACL3JB_000659"
     CDS             complement(38125..39024)
                     /locus_tag="ACL3JB_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0685444.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFCVLGAYLIWLRKKV"
     gene            complement(39134..39682)
                     /locus_tag="ACL3JB_000660"
     CDS             complement(39134..39682)
                     /locus_tag="ACL3JB_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0685445.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39900..41222)
                     /locus_tag="ACL3JB_000661"
     CDS             complement(39900..41222)
                     /locus_tag="ACL3JB_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0685446.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMVLPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(41313..41401)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(41565..43901)
                     /locus_tag="ACL3JB_000662"
     CDS             complement(41565..43901)
                     /locus_tag="ACL3JB_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0685447.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(44005..44553)
                     /locus_tag="ACL3JB_000663"
     CDS             complement(44005..44553)
                     /locus_tag="ACL3JB_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0685448.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(44550..44852)
                     /gene="zapA"
                     /locus_tag="ACL3JB_000664"
     CDS             complement(44550..44852)
                     /gene="zapA"
                     /locus_tag="ACL3JB_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0685449.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44939..45820
                     /gene="rnhC"
                     /locus_tag="ACL3JB_000665"
     CDS             44939..45820
                     /gene="rnhC"
                     /locus_tag="ACL3JB_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0685450.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANCFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45824..46438
                     /gene="lepB"
                     /locus_tag="ACL3JB_000666"
     CDS             45824..46438
                     /gene="lepB"
                     /locus_tag="ACL3JB_000666"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0685451.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            46717..49083
                     /locus_tag="ACL3JB_000667"
     CDS             46717..49083
                     /locus_tag="ACL3JB_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0685452.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(49131..50414)
                     /gene="tig"
                     /locus_tag="ACL3JB_000668"
     CDS             complement(49131..50414)
                     /gene="tig"
                     /locus_tag="ACL3JB_000668"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0685453.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(51213..52349)
                     /locus_tag="ACL3JB_000669"
     CDS             complement(51213..52349)
                     /locus_tag="ACL3JB_000669"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGR0685454.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIADEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(52411..52848)
                     /locus_tag="ACL3JB_000670"
     CDS             complement(52411..52848)
                     /locus_tag="ACL3JB_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0685455.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPIGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(52850..54805)
                     /locus_tag="ACL3JB_000671"
     CDS             complement(52850..54805)
                     /locus_tag="ACL3JB_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0685456.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRAIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(54829..56598)
                     /locus_tag="ACL3JB_000672"
     CDS             complement(54829..56598)
                     /locus_tag="ACL3JB_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGR0685457.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLGSPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        16828 a        12781 c        10618 g        16529 t
ORIGIN      
        1 ttgacttttc ttatagtttg tctttcttct atcttccatt atatcatact ttttcagtct
       61 atggtagctc tctttaaaag gctccgatac tgccgccacc tccgcctcca gagaagccac
      121 cgccagaact tccacttcca gaagatacgg agtaggtact tgctgtattt gcgacactag
      181 cataatggct catttgcgcg cttgaatgat aaaacatact gtgccagcca taagctacat
      241 agagattgat atctggattt tcaacttgaa tctgatgaac cttcatcaaa tgactaacct
      301 tgtccgcata gccaaataag gttgcataga ccaagagacg attccaaaca acaatacttt
      361 ccaattcagc cttatccagt cgtgcaatct cacgtaacat attttcaaaa ctggtccaga
      421 gatagtagac ctcagctccc gcttcattta gaacaccatc acgattatct agtcgaagct
      481 tccaataata gaaaacagac aaaactaacc ctagaaaacc aagtattggc aaagggaggt
      541 aaagatagcc atgaacgtct aaactgtaca agaacaaacc aaatccgata aataggggca
      601 agatagtcaa gacacccata cccacttgca aagtcttttc caaaccagtt aaaggacgat
      661 agtaatctgg gagcccccag aaggaaactc gttttctcac tccttcttgc atctggttca
      721 atacctcttc aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt ttttcatcag
      781 aaactttggc tctacgataa agactatcag ataccttgta atccgcaaac aaattggaaa
      841 gagtggcttc ttttttgcct gaaaaggcta gatttagaca gtctctctca aatcttgaca
      901 aaccatcttc tttcaccaat ctcaagccaa ctgcatctcc ttctgaaata atagagacat
      961 tcccacggtc tatcacatct agcaaggtag cttgaataag ttgatcaaag gtgaattttc
     1021 cagctccctt gaccaaggga ctcacttcct ccaaggaggt cgagtagact gcttctgata
     1081 aaaccatagg ctctaattcc attggtggtt catagagacg atgatttttg gcatatttga
     1141 ctgaaggagt ggtctttctt ctataaataa aatagaagca gacactcaat aacaaggaga
     1201 tagaaaggat cgaagggagg acccaagtaa cgagttgttt actctgatct ttttctctaa
     1261 caatcgagtc ttctatctta ttaaactctt ctaaacgatt ccctttcaag ccctgatccc
     1321 tagcgctagc aaaatcggtc cgagaccaat aggcatgcaa ctcaactcca cgcttagccg
     1381 gaagattgtc taaacggata gtataatcaa ggttactctt ttcaatcgtt ccctctctaa
     1441 aaagtttccc tgtatggaaa aagagttttt cagccccctt gtctcccctt acatgaaatt
     1501 caaacttttc aatagactct gaactatctg tcagaggttg ccaatttaat tcagcgatat
     1561 catcataaag gaaaagtaaa ttttttaagt tccagacgag gtcaacttca actatgtcgc
     1621 cctcctgacc tggattatag actctcacag tataaccatc cgcttcttct gttacttcgc
     1681 tagtcacatc tgctagttct gcaccgtttt tcgcagcctg aacctttgga tgagggtcaa
     1741 tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc cacgatttgg cccttaaagt
     1801 cctcctcaaa ctggtaaact atcttctgtc taaactctgc cgtattatct gcatgaatat
     1861 acaaatcccc ttgataagag tttatcttga aatcaatggc aaaaacagag agtggaagaa
     1921 ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt catcaactaa gccccctttt
     1981 tatctttctt atcattatag cattttttcg taagtaaagg cttacttatg ttgaaaaatt
     2041 acgcattttt cgataaaata ggagacagtt attttttaat agatcagaat aggagaaatc
     2101 atgagaaaaa tatacttatc tattttcaca agtctcttgc tgatgctagg acttgtcaat
     2161 gttgctcaag ccgatgaata tttacgcatc gggatggaag cagcatatgc tccctttaac
     2221 tggacccagg atgatgatag caacggagct gtcaaaatcg atgggaccaa tcagtatgcc
     2281 aacggatacg atgttcaaat cgccaagaaa atcgctaagg acttaggtaa agaacctttg
     2341 gttgttaaaa ccaagtggga aggtctagtc cctgccctta cttctggtaa gattgacatg
     2401 attatcgcag gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt ttcgagcagt
     2461 tactacacta gcgaaccagt tctactggtc aaaaaagatt ctgcctatgc aagtgctaaa
     2521 tctttggatg actttaatgg tgcgaaaatc acttctcaac aaggggtcta cctttatgac
     2581 ttgattgcac aaatcacagg tgctaaaaaa gaaacagcca tgggagactt cgctcaaatg
     2641 cgccaagctc ttgaggctgg tgtcatcgac gcctatgttt ctgaacgccc agaagctctg
     2701 actgccgaag ccgctaactc taagttcaag atggtccaag tagaaccagg tttcaaaact
     2761 ggggaagaag atacagctat cgccattgga cttcgtaaag atgacactcg tattagccaa
     2821 atcaatgcca gcattgaaac catttcaaag gacgaccaag ttgccctgat ggatcgtatg
     2881 atcaaggaac aacctgccga agctacaaca actgaagaga ctagcagtag tttctttagc
     2941 caagtcgcta aaattctttc tgaaaactgg caacaactct tgcgtggtgc tggtatcact
     3001 cttttaatct ctatcgtcgg aaccatcata ggtctcatta ttggacttgc cattggtgtt
     3061 ttccgtactg ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa actagtcggc
     3121 tgggttctca atgtctacat tgaaattttc cgtggtaccc caatgatcgt tcaatcgatg
     3181 gttatctact atggaactgc ccaagctttc gggatcaacc ttgaccgtac actggctgct
     3241 atcttcatcg tttcaatcaa taccggtgcc tacatgactg aaatcgtccg tggtggtatc
     3301 ctagcagttg acaagggaca atttgaagct gcgactgctc ttggtatgac ccataaccag
     3361 accatgcgta agattgtcct acctcaggta gtccgtaaca tcctacctgc aactggtaat
     3421 gaatttgtca tcaatatcaa agatacatct gtattgaacg ttatctctgt tgtcgaactt
     3481 tatttctcag gaaataccgt ggcaacacaa acctatcaat acttccagac atttacaatc
     3541 atcgccgtga tttactttgt cctcaccttc accgtaacac gtatcctacg atttatcgag
     3601 cgccgaatgg acatggatac ctatactaca ggtgctaacc aaatgcaaac ggaggatttg
     3661 aaataatgac acaagcaatc cttgaaatta aacacctcaa aaaatcctat ggacaaaacg
     3721 aagtgctaaa agacatttca ctcactgtcc acaagggaga ggtcatctct atcatcggaa
     3781 gctctggaag cggaaaatcg accttcctac gctccattaa cctacttgaa acaccaactg
     3841 atggacaaat cctttatcat ggacaaaacg tcctcgaaaa aggctatgac ctcacgcaat
     3901 accgtgaaaa gttggggatg gttttccaat cctttaacct ctttgaaaat ctcaatgttc
     3961 ttgaaaacac aatcgtcgct cagacaactg tcctaaaacg cgaacgcaca gaagctgaag
     4021 aaattgccaa agaaaacctg gaaaaggtcg gcatgggaga acgctactgg caagcgaaac
     4081 ccaaacaact ctcaggtggt caaaaacaac gtgtggccat tgctcgtgcc ctttcaatga
     4141 atcctgacgc cattctcttt gatgaaccaa catcagctct cgatccagaa atggttggag
     4201 aggtcctcaa aatcatgcaa gatctggctc aggaaggctt gaccatgatt gtcgtaaccc
     4261 atgaaatgga atttgcccgt gatgtctctc accgtgttat ctttatggat aagggtgtga
     4321 ttgctgaaga aggtaaacca gaagacctct tcactaatcc taaagaagac cgtacaaaag
     4381 aatttcttca acgttatctc atactcaatg aaaatcaaag agcaaactag gcagctagcc
     4441 gcaggttgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt ttgaagagat
     4501 tttcgaagag tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct ttttgctgtc
     4561 ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa tccgccgtta
     4621 tccaaagatt aatcttcaaa tttttcataa tttttttcat agaaatcaat taggcctagg
     4681 gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc aatgatagac
     4741 atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt atcacgaacc
     4801 cagccaacaa ctgattctac tttttcaaag tttgtcttag ccatgttttt ctcctatttt
     4861 cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa aaaaacatat
     4921 attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc gataatatat
     4981 aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta ttattaccct
     5041 cttaaggtgc gaaattattc aagttcttaa aaatgcttct ctatttccgt aagatagctt
     5101 atttcttcga tttaagaact gaagatgata gttctaacct ttagaaatcc aagccttcac
     5161 tagctcaaaa actcctatct ttcttcctca ataaatcatc tgagagatag gtattcctta
     5221 tatccttcaa attcatcact cctttggata ttgaggtgct agcctagaag cagacacccg
     5281 attatctaaa ccatccttaa taaagatgac aagacagata aactcagtta attacttata
     5341 tatcctttta atatggtata tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa
     5401 tgaaaatcaa agagcaaact aggaagctag ccgcaagttg ctcaaaacac tgttttgagg
     5461 ttgcagatag agctaacgtg gtttgaagag attttcgaag agtattaaag acagtgtgac
     5521 tatgcttgtc aatagatagg aaatcaaaat gaaggatgga aatctgagcc aaacatcata
     5581 agtgctataa tgaacagaag taagaattgc acgataagtt ttctaaaacc ataggaatcg
     5641 tcccctttct tcatcttcat tatagcacat atacatcagt tgtacaaata atatgatatt
     5701 tttttattag tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat
     5761 aagctggatc aaaaccttcc attctacgga tcaaacctgc ataatcatgc ttatctgcca
     5821 aagcgatccc aatcaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac
     5881 gtgtgatatc atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac
     5941 gctgtggaaa attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt
     6001 ccatttctgg catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt
     6061 tccccttaat atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggct
     6121 ctgcgactat cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat
     6181 cgacacctac caaagtttga atatgttgac gagttgcttc ataggtcaac tgacctacct
     6241 tttgcacagc aatcccatcc gcaaatttat caatttcctt gagtttgact ggacctccag
     6301 cctcaaaggc agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct
     6361 ctggacttgt ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag
     6421 gaaccaagac agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag
     6481 caactgttcc ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat
     6541 tttcagagac tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta
     6601 gtttaatagt tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg
     6661 tagtaatagg cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc
     6721 cctgcgcatg atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga
     6781 gctgggaaat ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt
     6841 cttttttcaa ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg
     6901 gagtattcac aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta
     6961 acatataaaa cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca
     7021 tctccgaaaa cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct
     7081 ttaggaagtt cataacgatt tgtggaaatc caatcatata accattctac caaactttct
     7141 tcactatcat tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc
     7201 aaatccaacg tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt
     7261 tgatctgtca attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta
     7321 tcagtttcat cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa
     7381 cccctaaata agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca
     7441 gtcatttaaa cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaacc
     7501 gccatctatc gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc
     7561 gaatctaaca gctgatttag gtcctaatga tttaccaact atatttgtta atatttttta
     7621 tttctcaaaa tccatttcgc tatataacga gcagatttag tcgcaccagc tctctcaaac
     7681 ggagaatgaa tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca
     7741 aaggtcatat gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca
     7801 ttttcatcat acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta
     7861 attacattat acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat
     7921 aaaatcatct ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc
     7981 gtttttacca acgaatggca ttgctttacg caattctgca ccaacttttt caatttcaag
     8041 gttagctgct tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac
     8101 aaagtcattt gcaaatttac cattttggat gtctgccaag acagccttca tattttcttt
     8161 aacttgttca gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga
     8221 aatagattga cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat
     8281 ttcgtgaaga acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc
     8341 gaaacctgct tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa
     8401 atcttcttca gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac
     8461 acctttacac cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc
     8521 ataaagagct ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcctggtcc
     8581 tttaggagca cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat
     8641 gttgaaacca tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc
     8701 ttcgtacaat tcttgttgaa tttcgtctgg cgccaagatc ataataacat cagccaactt
     8761 agtagcttct gctactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt
     8821 acctggacgt acaccgataa taacgtcacg acctgaatca cgcaagtttt gagcatgcgc
     8881 atgcccttgt gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt
     8941 aacatctttt tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat
     9001 tgccttttag gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt
     9061 gcacccgttc gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg
     9121 ctcttttctg catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctactact
     9181 gttgcacgga aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac
     9241 atcttaacca aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga
     9301 atcacatcaa tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca
     9361 acatcaataa taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg
     9421 ctttcaatat taacctgacg acgagatagg acacctgtaa agcgattgag gactcctgaa
     9481 cgattttgta gttttgctgt taacattcta cgcatggaac tgcaccccca acatctcatg
     9541 attactctta ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc
     9601 aattagcata ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt
     9661 gtcaaactta tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt
     9721 atcaaagacc gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat
     9781 tccaagtgaa tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat
     9841 agccaactcc tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt
     9901 atctgggtta gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa
     9961 accacctgaa gtcactaact gacgttcatt ttggtaggga taatactgag ctgtccacat
    10021 ttggtgttga ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg
    10081 ttcaataact gcttgcggtt gaaccacacg ctctttcttg tcatacgaac gaacacgatt
    10141 cttgtcttta gtgactttct caatccactt ttcagtattg ttgtgaactg ttggttctgc
    10201 tagcaacatt tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat
    10261 cttgccaatc tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt
    10321 cttaggattc cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc
    10381 ttccgtcatg gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag
    10441 tgggtgactc gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata
    10501 gcgttctgca aattcattta gttccgtagc agcctcagca taactaattc caccaccagc
    10561 taacaagact ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc
    10621 attcggctca agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc
    10681 tgtttctaaa gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt
    10741 agttgcgata tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg
    10801 gtaattgtac ttagtgattg gcatggtaat tcctacgatg tctgcctcct gaaaggcatc
    10861 cttcccaatc cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct
    10921 catagcatcc gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc
    10981 aacacccaac tttccagttg atttggcata gccttcagct tcatgcaaac aaccttgctc
    11041 atggcgccct agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa
    11101 aaccgcacca ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa
    11161 aactaggtcc gaccccgtct taggagattc taaactgatt ttctccatta ttcccctttc
    11221 tttcctctta aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa
    11281 agaagaaatt ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt
    11341 attaaaaaga taccgatttc atttactaaa aagaaaaaag aactgatttc tcagtccttc
    11401 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    11461 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    11521 cgcttccgtc ttcacctaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    11581 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    11641 ccatacctaa attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    11701 ctgttgtgac gcttccgcta acgacatcgc taagagcagc tgtcatacgc tcttggtttt
    11761 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    11821 gagcctctac cactaccgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    11881 agatgttctt gttgtttggc aagaagatga tgttacgggc attaacctgt tcaacagcct
    11941 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    12001 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    12061 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    12121 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    12181 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    12241 cgaggagaga atctccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    12301 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    12361 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    12421 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    12481 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    12541 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    12601 ctgcgcgcat gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag
    12661 cagctccacg agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg
    12721 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    12781 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    12841 gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg
    12901 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    12961 ctccatctgg aactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    13021 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacgatta
    13081 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    13141 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    13201 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    13261 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    13321 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    13381 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    13441 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    13501 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    13561 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttaca
    13621 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    13681 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    13741 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    13801 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    13861 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    13921 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    13981 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    14041 gctcatctat cgattttctt acaacaatat ctaaatccaa atacagtaca cgagactcgc
    14101 ttacatactt tggaataaaa tatctaaaaa agccgcatat gaaagtccct caaaggggag
    14161 acgataacct ttcagaatac tactgtcaat ctaaacattc acaatctcac tattcaaagt
    14221 ctctagtctt ttttccatca attggaacca ttctcgcgga aggtcatcat taaaaacata
    14281 aaacttaaga ttataataga tgaacacaaa gagattttat tgttgtttca actttatcca
    14341 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ttttatctca
    14401 tttcttttta ttcccatcat atgtttctac gtaaccatta ttttcgccta ttcgttcgta
    14461 aaaccatacc agtggagatt ttagatgaag tcccattacg gtttacaatt tttacattac
    14521 gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtaagg cagttagcta
    14581 ggctacctac tttctgctac gacggaaaaa tccacaaatc aataccattc gtggattttt
    14641 cctagtgaag cgtttaggta agccgccata gcggttaccg attattagat tacgacacgg
    14701 agtttggcaa atcgattcta tttgccaaac gtagttagtg aggcagttag ctagttcgcc
    14761 aaatagcgac tagcgtccaa caatttggaa ctttagttcc aattgttggt actgagtcac
    14821 atcttctcct ctaactctac gtctggatac ttgtccgcaa accagcggag ggcaaagtca
    14881 ttttcaaaga gaaagactgg ttggtcaaaa cggtctttgg ctaagatatt gcgacttgac
    14941 gacatccgtt catccaagtc ctcaggcttg atccaacgaa cggtcttttt acccattggg
    15001 ctcatgacca cttccgcatt gtattcgcct tccatacggt gtttaaagac ttcaaactgg
    15061 agttgaccaa cagctcccag catgtactca cctgtttggt aattcttata aagctgaacg
    15121 gctccttctt gcaccaattg ctcaatcccc ttgtggaagg atttttgctt cataacattc
    15181 ttagcagaaa ctttcatgaa aatttcagga gtaaaggttg gcagtggttc aaattcaaac
    15241 ttgttttttc caaccgtcaa ggtatcccca acctgataag taccggtatc gtaaaccccg
    15301 ataatatcac ctgccacggc attgatcaca ttctcacgac tttccgccat aaactgggta
    15361 acattagata gtttagcccc cttaccagta cgagggagat tgacactcat gccgcgctca
    15421 aattcgcctg atacgatacg gacaaaggca atacggtcac ggtgacgagg atccatgttg
    15481 gcttggattt taaagacaaa gcctgagaaa tccttgtcat aaggatccac aatttcaccg
    15541 tctgttttct tgtgaccatg tggttctgga gcaaacttga ggaagatttc aaggaaggtc
    15601 tgcacaccaa agtttgtcag ggctgaaccg aaaaagacag gcgtcaattc tccagccaga
    15661 atagcttcct ctgaaaactc attcccagct tcatttaaaa gctcaatgtc atccttgact
    15721 tgctcgtaga aaggattgct accaaagagt ttgtccccgt cttctagact ggcaaaacgc
    15781 tcatcccctt tgtaaagctc taaacgttgg ttatagaggt catacaagcc ctcaaaggct
    15841 ttccccatcc cgataggcca gttcataggg tagctagcaa tgcccaagat ttcttccaat
    15901 tcttgcaaga gatccaaagg ctcacgaccg tcacggtcca gcttgttcat aaaggtaaaa
    15961 actggaatgc cacgatgttt cacaacctca aacaatttct tggtttgagc ctcgatcccc
    16021 ttggcagagt ccacgaccat gaccgcagca tccaccgcca tcaaggtacg ataggtatct
    16081 tctgagaagt cctcgtgccc tggcgtgtct aagatattca cgcgcttgcc gtcgtagtca
    16141 aattgcataa cagatgaagt aacagaaatc ccacgttgct tctcgatatc catccagtca
    16201 gatttagcaa aagtccctgt tttcttccct tttaccgtac cagcctcacg aatctcaccc
    16261 ccaaagtaga gtaactgctc agtgatggtt gttttccccg cgtccgggtg ggagataatg
    16321 gcaaaggtac gacgtttctt aatttcttct tgaatattca taagttctct ttctttgatt
    16381 ctctattttt cttgtttcaa tagctgagaa tgatttttac attggatttt accattcctt
    16441 tcaacactcc attatatcgg attttagcat ttttttcaat ttctatttct tttcacttcc
    16501 ccctccctta tttataggaa aatatggtaa aatagaacag actaaaaatc atcatttcac
    16561 gaaaggatgc aagatgaaaa ttacgcaaga agaggtaaca cacgttgcca atctttcaaa
    16621 attaagattc tctgaagaag aaactgctgc ctttgcgacc accttgtcta agattgttga
    16681 catggttgaa ttgctgggcg aagttgacac aactggtgtc gcacctacta cgaccatggc
    16741 tgaccgcaag actgtactcc gccctgatgt ggccgaagaa ggaacagacc gtgatcactt
    16801 gtttaaaaac gtacctgaaa aagacaacta ctatatcaag gtgccagcta tcctagacga
    16861 tggaggagat gcctaatgac ttttaacaat aaaactattg aagagttgca caatctcctt
    16921 gtctctaagg aaatttctgc aacagaattg acccaagcaa cacttgaaaa tatcaagtct
    16981 cgtgaggaag ccctcaattc atttgtcacc atcgctgagg agcaagctct tgttcaagct
    17041 aaagccattg atgaagctgg aattgatgct gacaatgtcc tttcaggaat tccacttgct
    17101 gttaaggata acatctctac agacggtatt ctcacaactg ctgcctcaaa aatgctctac
    17161 aactatgagc caatctttga tgcgacagct gttgccaatg caaaaaccaa gggcatgatt
    17221 gtcgttggaa agaccaacat ggacgaattt gctatgggtg gttcaggtga aacttcacac
    17281 tacggagcaa ctaaaaacgc ttgggaccac agcaaggttc ctggtgggtc atcaagtggt
    17341 tctgccgcag ctgtagcctc aggacaagtt cgcttgtcac ttggttctga tactggtggt
    17401 tccatccgcc aacctgctgc cttcaacgga atcgttggtc tcaaaccaac ctacggaaca
    17461 gtttcacgtt tcggtctcat tgcctttggt agctcattag accagattgg accttttgct
    17521 cctactgtta aggaaaatgc cctcttgctc aacgctattg ccagcgaaga tgctaaagac
    17581 tctacttctg ctcctgtccg catcgccgac tttacttcaa aaatcggcca agacatcaag
    17641 ggtatgaaaa tcgctttgcc taaggaatac ctcggtgaag gaattaaccc agaggttaag
    17701 gaaaccattc taaatgccgc taaacacttt gaaaaattgg gtgctattgt cgaagaagtc
    17761 agccttcctc actctaaata cggagttgcc gtatactaca tcatcgcttc atcagaagct
    17821 tcatcaaact tgcaacgctt cgacggtatc cgttacggct atcgcgcaga agatgcaacc
    17881 aaccttgatg aaatctatgt aaacagccga agccaaggtt ttggtgaaga ggtaaaacgt
    17941 cgtatcatgc tgggtacttt cagtctttca tcaggttact atgatgccta ctacaaaaag
    18001 gctggtcaag tccgtaccct catcattcaa gatttcgaaa aagtcttcgc ggattacgat
    18061 ttgattttgg gtccaactgc tccaagtgtt gcctatgact tggactcact caaccatgac
    18121 ccagttgcca tgtacttggc tgacctcttg accatacctg taaacttagc aggtctccct
    18181 ggaatttcga ttcctgctgg attctctcaa ggtctacctg tcggtctgca attgattggt
    18241 cccaagtact ctgaggaaac catttaccaa gctgctgctg cttttgaagc aacaacagac
    18301 taccacaaac aacaacccgt gatttttgga ggtgacaact aatgaacttt gaaacagtca
    18361 tcggacttga agtccacgta gagctcaaca ccaattcaaa aatcttctca cctacttctg
    18421 cccactttgg aaatgaccaa aatgccaaca ctaacgtgat tgactggtct ttcccaggag
    18481 ttctaccagt tctcaataaa ggggttgttg atgccggtat caaggctgct cttgccctca
    18541 acatggacat ccacaaaaag atgcactttg accgcaagaa ctacttctat cctgataacc
    18601 ccaaagccta ccaaatttct cagtttgatg agccaatcgg ttataacggc tggattgaag
    18661 tcgagctaga agacggtacg accaagaaaa tcggtatcga acgtgcccac ctagaggaag
    18721 acgctggtaa aaacacccat ggtacagatg gctactctta tgttgacctc aaccgccaag
    18781 gggttccctt gattgagatt gtatctgagg cagatatgcg ttctcctgaa gaagcctatg
    18841 cttatctgac agccctcaag gaagttatcc agtacgctgg catttctgac gttaagatgg
    18901 aggaaggttc gatgcgtgtg gatgccaaca tctcccttcg tccttatggt caagagaaat
    18961 tcggtaccaa gactgaattg aagaacctca actccttctc aaacgttcgc aaggggcttg
    19021 aatacgaagt ccaacgccag gctgaaattc ttcgctcagg tggtcaaatc cgccaagaaa
    19081 cacgccgtta cgatgaagcg aataaagcaa ccatcctcat gcgtgtcaag gaaggggctg
    19141 ctgactaccg ctacttccca gaaccagacc tacccctctt tgaaatttct gacgagtgga
    19201 ttgaggaaat gcggactgag ttgccagagt ttccaaaaga acgtcgtgcg cgttatgtat
    19261 ctgaccttgg tttatcagac tacgatgcta gtcagttgac tgctaataaa gtcacttctg
    19321 acttctttga aaaagctgtt gccctaggtg gtgatgccaa acaagtctct aactggctcc
    19381 aaggggaagt cgctcagttc ttgaatgctg aaggtaaaac actggaacaa atcgaattga
    19441 caccagaaaa cttggttgaa atgattacca tcatcgaaga cggtactatt tcatctaaga
    19501 ttgccaagaa agtctttgtc catctagcta aaaatggcgg tggcgcgcgt gaatacgtgg
    19561 aaaaagcagg tatggttcaa atttcagatc cagctatctt gatcccaatc atccaccaag
    19621 tctttgccga taacgaagct gctgttgccg acttcaagtc aggcaaacgt aatgcagaca
    19681 aggccttcac aggattcctt atgaaggcaa ccaaaggcca agccaaccca caagttgccc
    19741 ttaaactact tgcacaggaa ttggcgaagt tgaaagaaaa ctagacagaa caaaaccagc
    19801 cctaaggttg gttttttctt gacaaataga aagaaaacgt ttgcaatatt gcgtgtaaag
    19861 tttccaaaca agaaaactaa aaatcgcaac aataaggagt tatttatatg gctacaatga
    19921 aggcagctcg ctggcatgca gcgaaagatg ttcgtattca agaaatagaa gttcctgaag
    19981 tacttccgca ccaagtaaaa gttgcagtta agttcacagg aatttgtggt actgacctcc
    20041 atgaattttt agatggacct atctttatcc caacagatga gcacgtctat tctggtcaaa
    20101 aagcaccggt aacactggga catgaatttt ctggtgaaat catagaagtc ggaagcgatg
    20161 ttacccgtgt taaagttggt gatcgtgttg ctgtggaacc aattctagct aaaaataact
    20221 tagttggtga ttataatttg gatccaaacc ttaattttgt cggtttggct gcagacggtg
    20281 gatttgccaa atattgtgtt ttagacggtg acttagtaca tgtcattcca gatagtttga
    20341 gctatgagca agctgctctt actgaacccg ctgctgttgc agtctatgct gttcgtcaat
    20401 cttctttgaa ggctggcgat acagctgttg tctttggttt aggcccgatt ggtctattaa
    20461 ttgtagaagc tcttcgtgca gctggtgctt ctaagattta tgctgttgaa ctatcacctg
    20521 aacgtcaagc aaaagctgaa gagttaggag ctatcgttgt ccgtccggaa gaaggtgaaa
    20581 cagctgttga agctattcat cgtttaacaa acggtggtgt agatgtttct tatgaagtaa
    20641 cgggtgtgcc agtagtttta ggacaagcct tagctgccgt acataaagca ggtgagtgca
    20701 tggtggtctc tatctgggaa cgagaagcaa atattaatcc gaatgaattt gcaatccaag
    20761 aaaagacact aaaaggaatc attgcttatc gtcatatctt ccctaaagta ttagaattga
    20821 tggaacaagg ctacttctct gctgaaaaat tagttactaa gaaaattaaa ttggaaaata
    20881 tcgtcgaaga aggctttatc gaattaactc aagataagtc acaaattaaa attttggtag
    20941 aaccagaata aaaaatcaat ctttttaaga caatactaac aggtcggagt aaacttactt
    21001 cggccttttg aaatataata ctcttcgaaa atctcttcag accacgtcag cgtcacatta
    21061 ccgtatatat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
    21121 cagcttgcgg ctagcttcct agtttgctct ttgatttcca ttgagtatga gaagaaatat
    21181 agtggatact ctttaacatt aaccactcca cctgactagc caatattctt tttcgctcct
    21241 accaactccc aataactatt ttggctttat ttccagagta ttttatggta aaatgaagag
    21301 taataatatt tattaaagag gtaaaaacat gattgaagca agtaaattaa aagctggtat
    21361 gacctttgaa acagctgacg gcaaattgat tcgcgttttg gaagctagtc accacaaacc
    21421 aggtaaagga aacacgatca tgcgtatgaa attgcgtgat gtccgtactg gttctacatt
    21481 tgacacaagc taccgtccag aggaaaaatt tgaacaagct attatcgaga ctgtcccagc
    21541 tcaatacttg tacaaaatgg atgacacagc atacttcatg aatacagaaa cttacgacca
    21601 atacgaaatc cctgtagtca atgttgaaaa cgaattactt tacatccttg aaaactctga
    21661 tgtgaaaatc caattctacg gaactgaagt gatcggtgtc accgttccta ctactgttga
    21721 gttgacagtt gctgaaactc aaccatctat caaaggtgct actgttacag gttctggtaa
    21781 accagcaacg atggaaactg gacttgtcgt aaacgttcca gacttcatcg aagcaggaca
    21841 aaaactcgtt atcaacactg cagaaggaac ttacgtttct cgtgcctaat ctctagaaag
    21901 aggtcattct atgggaattg aagaacaact tggcgaaatc gttatcgccc cacgtgtact
    21961 tgaaaaaatc attgctatcg ctactgcaaa ggtagagggt gttcactctt tttcaaacag
    22021 atcagtgtct gatacccttt caaaactttc actcggccgt ggcatttatc ttaaaaacgt
    22081 ggacgaagaa ctcacagcag atatctatct ctaccttgag tacggagtaa aagttcctaa
    22141 ggtagcggtt gctatccaga aagctgtcaa agatgccgtc cgtaatatgg ctgatgtaga
    22201 actcgctgct atcaatattc acgttgcagg tatcgtccca gataaaacac caaaaccaga
    22261 attgaaagat ctatttgacg aggacttcct caatgactag tccactatta gaatctagac
    22321 gccaactccg taaatgcgct tttcaagctc tcatgagcct tgagttcggt acggatgtcg
    22381 aaactgcttg tcgtttcgtc tatactcatg atcgtgaaga tacggatgta caacttccag
    22441 cctttttgat agacctcgtt tctggtgttc aagctaaaaa ggaagaacta gataagcaaa
    22501 tcactcagca tttaaaagca ggttggacca ttgaacgctt aacgctcgtg gagagaaacc
    22561 tccttcgctt gggagtcttt gaaatcactt catttgacac tcctcagctg gttgctgtta
    22621 atgaagctat cgagcttgca aaggacttct ccgatcaaaa atctgcccgt tttatcaatg
    22681 gactgctcag ccagtttgta acagaagaac aataaaaaga aaaagtgttt gatatctatc
    22741 aaacactttt tctttgcctc ccactatcta aaaaaatgat aatagatata attgtaaaca
    22801 aaaatccaga taggttttgc atgattgaga aagttaaaaa aactatggca gagaatcgtt
    22861 aatctcagat tgtcggtaga acgataaaca agggcaaaaa agaaaccaat cagactataa
    22921 tataataaac taattggatc tctgtgagat agtatcaaat gactaagccc aaagataagg
    22981 cctgataaga tgacatctaa ataatacttg gactagggaa agaaggtatt cataaaatac
    23041 cctctatcaa gagtctcctc aaaaacagga ccgatgatta caggcaggac aaaagataag
    23101 atagtcgata aaaaggttgg ttgtccattt gaaagaacca cggtaaaata ctcatcatga
    23161 atattcctat gattaatcaa atgagcatag cgtgcccaaa aattaccgag aatctgataa
    23221 accacataag ttgcaaataa ggagaagaca aatgaccagt tccagctctt tttctcaaag
    23281 ataaagagca tctttttctt ttttaacctc caaattaata gaaaaggaaa cttcccacta
    23341 atcccactgt taaaataaga gaatagacat cagctcctaa ccctaaaatg atcgtcacat
    23401 acaatccaat tgtttgtggt aaataggtag atagtaaaat aataagcaaa aatattccaa
    23461 attgtcttag tttctttgtg tttctcatcg tacttttttg aaagattacc ctgttcggaa
    23521 gccgtacttc caagcatcta tataagaatt aagtgcccct tgcctcatat aaggagcaaa
    23581 ttctctataa tataaccatc tactatatcc atcttcccaa acagcaagac cacctgaagt
    23641 ttgctccaag tcctcagttg aaagaactgt aaatgtattt gtacctgtca ttgcaagtac
    23701 cttcttaaaa tatagtgatt tgaaataaga tgtgaacaac tctatcagga aagtcaaatt
    23761 aatttataga aatattttag cagccaaggt gtactgttat agattcaata cactataaat
    23821 ttttgtaagc ttacatctac agtatacatc ttttttgtct attttatagc ccatctcctc
    23881 aactgtcaat ttttcaacct gaattgcatt tttccataaa aaatgagacc tttctagtct
    23941 catttagtca ttcttagtat tttctaaatc gttgatagcg ttcttccagc aactcttcta
    24001 gcggtttttg tgaaagtcta gccagctccg tttggagttc ttttttgaca ctcttaatca
    24061 gttctttact agaaagtcct acttcagaaa tcaccttatc caccacgtcc atttctaaca
    24121 gttcatgcga agtgattttc atcagttctg ctgcttccat ggcgcgagta ccgtccttcc
    24181 ataaaatgga agcaaagcct tctggactga gaatggcata gatagaattt tccagcatcc
    24241 agacacggtc cgcgacagct agagccagag ccccgcctga accaccttca ccgataataa
    24301 tggcgataat aggaactttc aggtcactca tttccatgag attgcgagcg atagcttccc
    24361 cttgaccacg ttcttctgct ccgacaccag gataagcacc tgctgtatta ataaaggtca
    24421 caactggacg gccaaatttc tcagcctgtt tcatcaaccg cagtgccttt cggtagcctt
    24481 ctggatgtgg ttggccaaaa ttccgtttga ggttgtcttg caaactcttg cctttttgga
    24541 taccaacaac tgttacagct tggtctccaa gccaaccaat accaccaaca actgcaccat
    24601 catcacgaaa agaacggtca ccatgtaatt ggataaattc atcaaaaatg cctgtcgcaa
    24661 agtccaaggt tgtcaagcga ctctgctcac gcgcttctct gactattttt gcaatattca
    24721 tctaggactc cctccatgca atctgactag gctagcaatc gtatctggta agtctcttct
    24781 tttgacaata gcatccacaa agccatgttc taataggaat tctgcctttt ggaaatcctc
    24841 aggcaagctt tcacgaaccg tattttcaat cacacgacgc ccagcaaaac caaccaagct
    24901 ctgtggttca gccagaatga tatcgccttc catagcgaaa gaagctgtca caccaccagt
    24961 cgttggatct gtcaaaatgg tcaggtaaaa gagaccagca tttgaatgac gtttaaccgc
    25021 cgcagagatc ttagccatct gcatgagact catgattcct tcctgcatac gggctccacc
    25081 agaggctgtg aataggacaa ctggcaattt ttcgacagtc gcatactcaa acaaacgagt
    25141 gattttttca cctacaaccg tacccataga agccatgata aagttagaat ccataatccc
    25201 aagagccaca gtctgacctt taataagagc agttcctgtc acaacggctt catgcagacc
    25261 tgttttttca cgcatagatg ccagtttctt ttggtaacca gggaaatgca agggatcctt
    25321 gctttcaatc cctgtaaaca attctttgaa ggttcccata tcaatcgtca aagccaagcg
    25381 ttcttgggca gaaatacgaa aggtatagct acagtgcgga cagatacgtt cacttcccag
    25441 atccttctga tagatggtat gcttacagcc tggacactgg gaaaataatt catctggaac
    25501 ctctggctta gcttgaggtt tttccctaac cgaacgattg ggattgattc gaatatactt
    25561 atctttttta ctaaatagag ccattgattc cccttttcgg tttaaactct taaagtcatt
    25621 ttattctttt tcttgatatt taggtaagaa ggtttccatc aagaaggaag tatcataatc
    25681 cccagcaatg acattgcgat ctgaaatgag gtcaagctgg aaatctgcat tggtctgcac
    25741 tccttcaatc tctaattcat agagggcacg ttgcattttc atcaaggcgt caaaacgatt
    25801 ttcgccgtgt actatgattt tggcaatcat actatcataa taaggcggaa tggtataacc
    25861 tggataaact gctgaatcca cgcgcaagcc aactccacca cttggcagat agagattagt
    25921 aatcttacct ggacttggag caaagttaaa ggctgggttt tctgcattga tacgacactc
    25981 gatggcatga ccgcgtagga caatatcttc ttgcttaaca gacaaaggct gacctgccgc
    26041 aatgcaaatc tgttccttaa cgatatcaac acctgaaaca aactctgtta ctggatgttc
    26101 tacctgaaca cgagtattca tctccatgaa atagaaattg ctacttgctt catcaagaag
    26161 aaattcaatg gttcctgcat tctcatagcc aacaaactct gccgctcgaa cagcagcagc
    26221 acctatttca tgacgcagcg tttttccgat tgcaatcgag ggactttctt ccaaaacctt
    26281 ttggttattc ctttgaagag aacaatcccg ctcacccaag tgaatcacat gtccatgctc
    26341 atcacctagg atttgaacct caatgtgccg agctggatag ataacccgtt ctatgtacat
    26401 ggcaccattg ccataattgg ccttggcctc actagaggca gtttcaaagg cagaaacgag
    26461 gtcatctggt ttttcaacct tacgaatccc tttaccacct ccacctgctg aagccttgag
    26521 cataacagga tagccaattt tttcagcaac aatcaaagct tcttcagagt tatgcacttc
    26581 tccatctgaa cctggtataa caggcacacc tgctttaatc atctgagcac gcgcattgat
    26641 cttatccccc atcatatcca taacatgacc agatggaccg ataaacttga tacctacttc
    26701 ttcacacatg gtcgcaaatt tggaattttc actgagaaat ccaaaaccag ggtgaatagc
    26761 ttctgcctca gtcaagactg cagctgatag aactgcatta atattgagat aagactctgt
    26821 tgccttgcca ggaccaatac aaactgcttc atctgccaaa agcgtatgaa gagcttcctt
    26881 atcagcagtt gaataaaccg ctaccgtcgc aatccccaat tcacgtgccg cacggataat
    26941 acgaaccgca atttcaccac gattggcaat taaaattttt cgaaacatgg agaacctcct
    27001 tagttcccaa ttgcaaaagt aaggatacca ctggctgcaa gcttgccatc cacttcagcc
    27061 tttgcttcaa ccacagctat ggtgccacga cgttttacaa aagtcgctgt cataaccaat
    27121 tggtcgcctg gtacaacttg cttcttgaac ttaaccttgt ccataccagc gtaaaagacc
    27181 agttttcctt tattttcagg ttttgataac tccaacacac cagcagtttg cgccaaggct
    27241 tccataatca gaacacctgg cataactggg tattgaggaa agtggccgtt aaagaaaggt
    27301 tcgttaatgg tcacattttt gatagcaaca atggtatcct cgctcacttc caagacacgg
    27361 tccactagaa gcataggata acggtgggga agagcttctt tgattccttg aatatcgatc
    27421 atttgatacg taccaatcct ttaccaaact caaccatttc ttcgttagag acgagaattt
    27481 ccgttaccac accatcctta ggagctggga tttcattcat gactttcatg gcttcgataa
    27541 ttaccaatgt ttgacctttt ttgacactat caccaactgt aacgaaggca ggtttatctg
    27601 gtccagcagc caagtaaacc actccaacaa gtggactctc tacaagattt ccctcagtag
    27661 ccacacttgc ttcagctgga gctggaactt cttctgctac agtctctgct ggagcagatg
    27721 taggagctac tggactcggt gttgctagaa cgggtgctgg agcgacttga gttgcaactt
    27781 caggcacagg tctcgcttca ttcttgctaa actgcaactc atccgtccca tttttataag
    27841 aaaattctct caaacttgac tggtcaaatt gagtcatcaa gtctttaata tcgtttaaat
    27901 tcatacttat ctattctccc aacgtttgaa agcaagaact gcattgtggc ctccaaaacc
    27961 aaaagtattt gaaatagcgt atggaatttc tttctccaag ccttgtccat aaacgacatt
    28021 agcttcgata taatctgata cttcacttgt cccagctgtc attggtacaa agttatggcg
    28081 catagcttcg atggtgacga tagcttctac tgcacccgca gcccccagca aatgtcctgt
    28141 aaaagacttg gttgatgata caggtacttc cttaccaaga acagctacga tagctccact
    28201 ttctcctttt tcattggcag gagttgacgt tccgtgagca ttgacatagg ctacttgctc
    28261 tggagaaatc tcagcttctt ccaaggctag tttgatggcc ttgatagctc cctgaccttc
    28321 tggatgtgga gaagtcatgt ggtaggcatc acaagtattt ccgtaaccaa ccacttcagc
    28381 caggatagta gctccacgtt tttcagcgtg ttcaagactt tctaaaacca acatccctga
    28441 accttcaccc ataacaaacc cattgcgatc cttatcaaat gggatcgaag cacgagttgg
    28501 atcctctgta gtagagagag ctgttaaggc ttggaaacca gcgatggcaa aaggtgtgat
    28561 agaagcttct gttcctccca ccaacatcac atcttggaaa ccaaacttaa tggagcggaa
    28621 ggcatcccca atcgcatcat ttgatgaaga gcaggcagta ttgatagatt tacaaacacc
    28681 gtttgcacca aaacgcatgg ctacattccc agaagccata tttggtaaag cttttggaag
    28741 agtcattggt ttgacacgtt tgggtccttt ttcatgaagg cgaagtacct gatcttcaat
    28801 ttccttgatt ccaccaatac cagatgcaac gataacacca aaacgatccc tattaagagc
    28861 ctctacatca agattggcat ggtttacagc ctcttgggct gcatacaagg catataaaga
    28921 atagttatca aaacggttgg tatctttttt tacaaagtat ttatcgaacg gaaaatcttg
    28981 gatttctgcc gcattatgca catcaaagtc actatgatca aattttgtaa tgccaccaat
    29041 gccgattttc ccagttgcta aactattcca aaattcttct ggtgtatttc cgattggaga
    29101 tgttactcca taacctgtta ccactactcg atttagtttc attcttttca cctctagctt
    29161 tcgctacata cttaagccac catcaatggc aatcacttga ccagttagat aatcttggcc
    29221 tgctaaaaat actgtcaaat ctgcaacctg ctctgcctgc ccaaattctt tcatcggaat
    29281 ctgagctagt gtagcttcct taatcttatc tgataagata gctgtcatat cagactcaat
    29341 cattcctgga gcaatcacat tgactcgtat attccgacta gcgacctcgc gtgccacaga
    29401 cttggtaaag ccaatcaagc cagccttaga agcagcatag ttagcttgac caatattccc
    29461 catcaaacca acaacactag acatattaat gatagcacct tctctggctt tcatcatcgg
    29521 tttcaagact gattgtgtca tattaaaggc accagtcaga ttgaccttga gcactttttc
    29581 aaaatctgct tctgtcatct tgagcataag agtatcttgg gtaatccctg cattgttgac
    29641 caaaacatct actgaaccca gttctgcaat agcttgatca atcatacgct tagcgtctgc
    29701 aaaatctgat acatctcctg aaatgggaac caccttgata ccatagtttg aaaactcagc
    29761 gagcaattct tctgagattg ccccacgact gtttaagaca atgttggctc ctacttgagc
    29821 aaacttgtgg gcgatggcaa gaccaattcc acgactcgaa cctgtaataa agatattttt
    29881 atgttctagt ttcatttttt tcctttcaaa acttctactt attttagtct atttttctaa
    29941 aagtgctact aaactcgctt gatcttccac atgagctaag tgagcagttt gatcaatttt
    30001 tttaacaaaa cctgacaaga ctttccccgg tccaatctcg ataaagttgc ttatgcctgc
    30061 ttcttgcatg accccaatac tttcatagaa acgaacgggt tccttgacct gacgcgtcaa
    30121 gagctgagca atgtcctctt tttgcatcac agcagcttct gtattgccga ctaggggaca
    30181 agtaaaatct gaaaaactta cctgagctag agtttcagct agtttctggc tagcaggctc
    30241 aaggagagcg gtgtgaaagg gacctgacac cttaagagga atcaagcgtt tggcacctgc
    30301 ttcttgcaaa agttcaaccg ctcgatcaac tgcaaccact tctccagcaa tgacgatttg
    30361 tgcaggtgtg ttatagttgg ctggagtaac cactccaagt tcagaagctt tttgacaggc
    30421 ttcttcaatg acctctactg gcgtattgag aactgctacc atcttgccag agtcagcagg
    30481 agccgcttct tccatatagg ctccacgctt agctaccaag gcaaccgcat cttcaaaatc
    30541 caaggcgccg cttgccacca aggcagagta ttctccaaga gacaaaccag caaccatatc
    30601 aggctgatag cccttttctt gcaataaacg gtagatagca accgaagtcg ctagaatggc
    30661 tggttgcgta tagcgggtct gattgagttt gtcttcttcc gtatcgatga gataacgtaa
    30721 atcataaccg agcacctgac tcgctcgatc aatcgtttct ttgacaatcg gatactgatc
    30781 atagaaatcc cttcccatcc ctagatactg ggcaccttga ccagcaaata aaaaggctgt
    30841 tttagtcatt tcttacaact cctgcccagc gagaggcttc ttcttgaatt ttcttagcgg
    30901 ctccgtaata caaatctttt aggatttctt cagctgtttc ttctttagaa acaagccctg
    30961 cgatttgacc tgccatgaca gagccaccat ccacatcacc gtgaacaact gctttggcta
    31021 gggcacctgc tcccatttgt tcaaagattt ctaaatcagg atcttcctgc ttaaaggcat
    31081 ctttttcagc cagttcaaaa tctctagtca actgattttt aatagcacga acagcatgac
    31141 caaagtgctg agctgaaatc gtagtatcaa tatcccttgc ttttaaaatt ttctccttgt
    31201 agtttggatg ggcattcgac tcttttgcaa ctacaaaccg tgtccccacc tgtacagcct
    31261 ctgcacctag cataaagcca gccgcagcac cttcaccatc cgcaattcct cctgcagcaa
    31321 taacaggaat agatatagct gtggctacct gtcgcaccaa ggtcatggtt gttaatttac
    31381 cgatatgccc cccagcttcc attccttctg caataacagc gtctgcaccg attttttcca
    31441 tgcgtttagc taaagcgaca ctaggaacaa caggaataac gattatccca gcttcatgga
    31501 aacgttccat atacttgctt ggatttcctg ctcctgttgt gacaacttta acaccttctt
    31561 caataacgag atccacgata tcttccacaa agggagataa gagcatgatg ttgaccccaa
    31621 agggtttatc agtcaatgat ttgattttat caatattggc cttgacaact tctttcgggg
    31681 catttccccc accgataatt cctaatcctc cagccttgga aacagcccct gccaaatcac
    31741 catcagcaac ccaggccatc cctccttgga aaataggata gtcaatcttc aataattctg
    31801 taatacgcgt tttcatagtg cctccaacct tccttgctta cgtaatagtt cgatttcacc
    31861 ataatttgac agtcaaacta ttacctaaac aagagggagt gggtttctcc ctactccttc
    31921 tactaatatt ctgcttattt tgcttgctct tcaacgtaag caaccaagtc accaactgtt
    31981 ttcaagtcat tttctgcttc gatttggata tcaaaagcat cttcgatttc tgagattact
    32041 tggaacaagt ccaatgaatc tgcgtccaaa tcatcaaaag ttgattcaag tgttacttct
    32101 gatgcgtctt ttccaagttc ttcaacgata atttcttgta ctttttcaaa tactgccatg
    32161 ataggactcc tttaaaataa atagtttttt tataacaatg tgttcaccac atgattacct
    32221 aaattgtaag aatgagcgtg ccccaggtca agcctccacc gaagcctgat agaagaacag
    32281 tctggctacc atctaaaggg atgagacctt gttctacaca ctctgaaagt aaaatcggga
    32341 tactggctgc actggtattg ccatattcca tcatattggc tggaagtttg gctcggtcaa
    32401 caccaatttt tctagccatc ttatccaaaa tacggtcatt ggcttgatga agtagcagat
    32461 aatccaagtc tgtcacctct ataggagatt catcaatagt ctgcttgata gacttggcta
    32521 catctcgaat ggcaaaatca aagactgtgc gtccatccat cttcaaaaac gaatctgcac
    32581 tttcttgatc tgaaaatgga gaatgcaaac ctgaatgccc ataagttaaa cactcgctgc
    32641 gacttccatc gctattgaga ctctcagcta agaaatgctc ttgctcgcta gcttctaaca
    32701 agacaccacc agcaccatct ccaaacaaca cagctgttga tcgatccgac caatcgactg
    32761 ccttagagag ggtttcacta ccaatcacca agcctttttg aaagcgacca gaagcgataa
    32821 acttttcagc agttgaaaga gcaaatacaa atccactgca agccgcggtt aagtcaaaag
    32881 caaaggcttt attagcgcca atattagctt gaacacgagc agctgtagag ggcatcatcg
    32941 aatctggagt aatggtagct aggatgataa aatccagttc ttttcctgtt attccagctt
    33001 ttgccatcag tttcttagca acctctgtag ccaaatcact ggtagattct gttcttgaaa
    33061 tatgcctttg tcgtattccc gttcgacttg aaatccactc atcattggta tccataatct
    33121 gagccaagtc gtgatttgta accacttgct ctggcacata atgagcaacc tgacttattt
    33181 ttgcaaaagc cattatttca aatcctccaa aaattggtaa agattagtca aacctttacc
    33241 catgacagca atttcttcct cgctcatgcc atcaataatt ttttctacca tggccttgtg
    33301 gaagcgttta tgcagcctat gaatcaagcg acccttcttt gtcaaatgca gatgcaccac
    33361 acgacgatcc tgttctgacc gaactcgctc aatgtagccc ttacgctcta aattgttcaa
    33421 acttgtcgta acagttccaa gagttaccat caactctttt gacacttgac ttggagtcac
    33481 gtctggagcc ttaccgatga catcaatcgt atgcatttct ttgatggaga tatccttaaa
    33541 acgactacct ctcaagttca cttcctcaat tacaaggaca ttgttaaata tagatgttaa
    33601 atattcattg attcgttggt agtccatttt tcatatccct ccttcttcaa aaaactttta
    33661 caatcaaaac atttgacaga aagaattata tcaaaattca aagaatgatg caagtatttt
    33721 ttattttcct gtaaatttag gtcttcttct ctccgaatga gctcgcactc cttctttgaa
    33781 atcctctgtt tgagctaagg atttctgtag gttcagttct aaagtagcgt aaccctgcca
    33841 gtctttaaat tggctctccc aaaccaactt cttaatggca gcataggaat tacttgaaac
    33901 acgtcttaat tttttaagaa gctgttctct cgtcttttca agtttttcag cttcagaaac
    33961 gcggtaaacc aacccccatt ctagggcttt ttctgccgtt aaagcctctc ctgtcatagc
    34021 taattgagca gcacgcgtca caccgatact gcggctcaag agatgaattc cccctgcatc
    34081 tggagccaaa ccaacaccaa caaaggcttg gataaactta gccttatccg tcgccaaaca
    34141 gaaatctgcc gcaacagcca tattcgctgc ggcacctgca acagcaccgt caacttccat
    34201 taaaacaggt ttggctattt gcttgatttt ataagaaatc gtattgacca actctgcgat
    34261 ttttgtcaat gatggaatat catcctcatc cactgcccgc ttcatctcta ccaaatctcc
    34321 cccaactgag aagacctttc cattggcatt gattaagata aaatgcacag ctggattttc
    34381 ttctgccaaa gtcagagctt ctaaaatctc ctcacacatg ggaatatgaa aaccatttgc
    34441 gacctcagga cggttcaagg taaggattgc caagtcctct tcaagctgat aaataatgtg
    34501 ttccatcagg gctccttttt attttataag cagtttatac tcttcgaaaa tctcttcaaa
    34561 ccgcgtcagc ttccatctgc aacctcaaag cagtgctttg agctgacttc gtcagtctta
    34621 tttacaacct caaagcagtg ctttgagcag tctgcggcta gcttcctagt ttgctctttg
    34681 atttcattga gtgttaaatt atttcactgt caaagtatat cttttttagg agcagaaagc
    34741 aagaaaaaat cgactgaaag tgtctcagcc gataagaaag gctcgcttta ggctagaaag
    34801 catcttattt tcttcattga aaaaagcctt tctttctgct ataatcgtat aaaatactta
    34861 ctttaggagt tcttatgaaa gttgttaaat ttggaggtag ttctcttgcc tctgctagtc
    34921 aattagaaaa agttttaaac atcgtcaaaa gcgattcaga gcgtcgtttt gtagtcgttt
    34981 ctgcgcctgg taaacgcaat gctgaagata ctaaggttac ggatgccctg attaaatact
    35041 accgcgacta tgttgcgggt aacgatatta gcaagagcca aagctggatt atcgaccgct
    35101 atgctgctat ggttagtgaa ttgggactaa aaccagctgt gctagaaaaa atttctaaaa
    35161 gcattcacgc cttggccact cttcctattg aagaaaatga atttctctac gatactttcc
    35221 tagcagccgg tgaaaataac aatgccaaat tgattgctgc ctactttaac caaaatggta
    35281 tcgatgcacg ctatatgcac cctagagaag ctgggattgt ggtcacaagt gaacctggtc
    35341 acgctcgcat cattccatca agttatgaca agattgaaga attgacaaac accaatgaag
    35401 tccttgtcat tcctggtttc tttggtgtca ctaaggaaaa tcaaatctgt actttctcac
    35461 gtggaggatc tgatattaca ggttctatca ttgctgctgg tgtcaaagct gacctctatg
    35521 aaaactttac ggacgttgat ggtatctttg cagcccaccc tggtattatc caccaaccac
    35581 actcgattcc tgagttgacc taccgtgaaa tgcgcgagtt ggcctatgca ggcttctcag
    35641 tccttcatga cgaggctctt cttcctgcct accgtggaaa aattcctctg gttatcaaga
    35701 ataccaacaa ccctgaccat ccaggtactc gtatcgttct aaaacacagt aatgatgaat
    35761 ttccagttgt gggaattgct ggtgactcag gctttgtcag cattaatatg tcgaaatacc
    35821 tcatgaaccg tgagattgga tttggccgca aggttctgca aatcctggaa gaacttaaca
    35881 tcggttggga acatatgcca acaggtatcg acgatctttc tatcattctc cgttctcgcc
    35941 aactaactcc catcaaggaa gaagaaatcc tgcgtcagtt ggttcaaaag gctaaagtag
    36001 atcatgcaga aatcgaacac gacctttcta tcattatgat tgttggtgaa aaaatgaaga
    36061 gccatatcgg agtgactgct actgcgacac gcgctctatc tgaaaacaaa atcaacatcc
    36121 agatgatgtc tcaaggttct agtgaagttt ctattatgtt tgttgtcaat aaagaccaag
    36181 agaaagcagc aattaaagcc ctctacaatg ccttttttgg agaaagtaag gaagactaag
    36241 catggcccaa tcacttaaca aaacagtact cctcagtacg acaggcactt cctacctctc
    36301 tatcgctggg aaagttggga aattccttgt cggagatcag gctttggaat tttacccaga
    36361 tgtcaatgtc gaacaattta tccagattcc ttggagccat atcaatcaga ttggagccaa
    36421 tgtcactgga cgcaaaatca gccgccactt cgaagtcttt acagacaaag gaaaattcct
    36481 ctttgcttca aaagactcag gtgccattct caaaattgca cgcgaaaaac taggcaatga
    36541 caaggtcgtc aaacttccga ccctgattca gacaattagc caaaaattta aaaatctatt
    36601 tgcaaaaaag tagaaacttt agtataatca tagcaacgga taagtaggtt atcttcttct
    36661 ttcagaaagt ctgcgggtgc tgcgagcaga taggagggat aggtgaaatt ctaccgttag
    36721 tgacaattac atacacaatc aagtgcacac ctgtgaagtt ggatggaacc gtggccctgc
    36781 cactccaacg ttttgtcagg gtgctttttt cataaaggag ttcttatgtt agatatcaaa
    36841 cgtattcgta cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagatgct
    36901 gctgtcttga atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt
    36961 gaaactctca aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac
    37021 aaggaaaata cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc
    37081 ttggatgctg aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca
    37141 aatatcccag ctgacagcgt tcctgttggg gctgacgaag acgacaatgt ggaagttcgc
    37201 cgttggggta ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa
    37261 gaccttggta tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc
    37321 tataaaggcc tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat
    37381 ggaaaagaag gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt
    37441 ggtactggtc agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt
    37501 gtcttgattc caactgctga agttcctctg acaaactact accgtgatga aatcttagac
    37561 ggcaaagatc ttccaatcta cttcactgct atgagtccgt cattccgttc tgaggctggt
    37621 tctgccggtc gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg
    37681 gtcaaatttg ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct
    37741 gaaaacattc ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat
    37801 atgggcttct cagctacgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat
    37861 taccgtgaaa tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc
    37921 cgttaccgtg atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga
    37981 cttgcagttg gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatggttct
    38041 gtgaccatcc cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa
    38101 aaaataaggt ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc
    38161 tagtacacag aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag
    38221 aaatggaagt ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg
    38281 gaaggtgagg gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt
    38341 taaaacaaag aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg
    38401 caggctggtt cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta
    38461 gattccttct tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat
    38521 aaggggatag agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc
    38581 gataatacct accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt
    38641 ccaacttgga gtggcatgaa ccctccgccc tggacaagca aacttgatgg taaaaccagc
    38701 aatcaaggtc aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag
    38761 ataagagaat acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc
    38821 cattcctgac aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag
    38881 atgcagaatt agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag
    38941 aaccggcaac gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga
    39001 aaatactaag gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac
    39061 ataaaagcgc ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt
    39121 actcagatat gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt
    39181 tgttggcata gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt
    39241 gttgagtgta gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg
    39301 tattgataac tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg
    39361 gagtacgatt gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa
    39421 aggctgtgtg acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca
    39481 ccacttcacg ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttggt
    39541 aggcttctaa aacagtcggg gcattggcca agagaccgat taggttggga atatagccat
    39601 tgttgtcttt ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg
    39661 tatggatagt aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt
    39721 ggaaaatctt ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat
    39781 aagattttcg ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat
    39841 atatcaggct gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat
    39901 tatttgtcaa aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca
    39961 atcaagtttg gcagaaccat caaggcatta acgatatctg cgataatcca gaccatatcc
    40021 aactcgataa atcctcctaa caagaccatg agcacaaaaa ccacacggta gagccagata
    40081 aagcgaaccc caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc
    40141 gttgtaaagg caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag
    40201 actgttgaga aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca
    40261 gttaccaaga tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct
    40321 gtcatggaaa tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata
    40381 ggagcagaac ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata
    40441 gccatccgaa cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag
    40501 gtaaagacta aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga
    40561 gttcctaaga tataaatgat ggccataaaa ggaacaacag tagttgaaac cttagaaata
    40621 gacttgagtc caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg
    40681 gctggcgaaa tcgtcgttgt attttggata gattctgcaa tcgagttgac ttgggtgaag
    40741 gttccgattc ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt
    40801 cgccactttt ctcccatccc tagaaggata tagtgcatgg gacctcccgc tactgcacca
    40861 tggtcgtcct tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt
    40921 ccaaagaaag ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc
    40981 gtcgcaactc ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct
    41041 gcaaaactgg atacatcacc atgtccctta tcctggataa aaataagctg aaaggccttg
    41101 ggcagacgca aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc tgttccgacc
    41161 aataaaatca agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac
    41221 attttcttct cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc
    41281 tggaatgctt agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga
    41341 gtttgagcag ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc
    41401 catttacagt catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg
    41461 gtatttaatt gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta
    41521 aaaattagtt caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg
    41581 acaatagtcg caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt
    41641 ttgtttcttt gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg
    41701 atgatatcaa cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca
    41761 ttcatggctt cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca
    41821 gaagttcgtt tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga
    41881 acaagatcaa actctttctc ttccaaggtc atcttaatca agccaacttg ggcttcccag
    41941 cgaccgtcct tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata
    42001 tcatctccca cctttggagc tcgttttttc ttggcctttt gaaggacctt atttttagac
    42061 aagtccactt tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg
    42121 ggcttgagtt gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc
    42181 atatccacaa tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga
    42241 ttaagctcgt tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc
    42301 tcacggatat tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg
    42361 atacgattga cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca
    42421 gataggccta gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata
    42481 aagcgatagg tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag
    42541 gctgtctcaa taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt
    42601 tgacgcaggc gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca
    42661 gtaccagccc ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata
    42721 tccacgatat tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca
    42781 tctccaatat cagcaaagat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa
    42841 atcggcaatc ctgactgggc catgacctgt gtcaagccca gagttttgag catgatggtc
    42901 ttcccacctg tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca
    42961 tcatttgcga cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga
    43021 ttttctgaca gctgaggcac gactgcttgt ctttcttgga taaatcgaac cttggcacga
    43081 atcaagtcca gatgaccgat aatccaagcg tcattagcaa tctcagccgc atgagggcgg
    43141 acacgctcag aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga
    43201 ctagcaattt cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca
    43261 ctagcagaaa tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt
    43321 aaaacctgac ggccatttct gctagcaaca attccttccg tcaacatctg cgctttttgc
    43381 ttgagcaagt cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg
    43441 attcgcgcca attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga
    43501 agatttcctt gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc
    43561 aagctgacat tttccagatt ggtgtaaaaa ttttgaagtt ctcggctggc aagaagcacg
    43621 cgtttcaaga gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag
    43681 actcctgcaa tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc
    43741 tgcatttcct tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc
    43801 agttgtctca attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg
    43861 accttatcga actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg
    43921 aatgtctagg tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa
    43981 gggctaggaa aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag
    44041 ccaactggtt gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag
    44101 aggattttgt ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac
    44161 aaataaggtc accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag
    44221 ttttttgcta ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat
    44281 cccaaataca agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg
    44341 atccgatggg aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa
    44401 atggaattgc tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc
    44461 tgaaatcagg taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca
    44521 aaccaagacc aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct
    44581 tgcttacaag tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat
    44641 tcaatctcac ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt
    44701 tcatcatctg cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta
    44761 gcgatttcct ccataaaaag gttatcatgt tcgcttgtca aggttaacga ttttttcccg
    44821 aatgtaaatt tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa
    44881 attcgctaat tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat
    44941 ggcaagtatc acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca
    45001 aaccagtctg gctcccagta agaatcccta tatccgctac tttttgaaac tacctcaagc
    45061 aacggtttct atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgagaaata
    45121 cgctagtttc tttggctatc aacttgtaga ggaaaacagg gggcaaaatc ttcctttgat
    45181 tgggacagat gaggtaggga atggttccta ctttggtggg cttgcagttg tggcttcctt
    45241 tgtcacacct gaccagcatg ccttcttacg aaaacttggt gtgggagatt ctaagactct
    45301 gaccgaccaa aagattcgtc agattgctcc tattctcaag gaaaaaatcc agcaccaggc
    45361 actccttctc tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc
    45421 ggttaaggtt gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc
    45481 tgagaaaatt gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca
    45541 agaagccaat tgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt
    45601 ggctgtcgca gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc ttgaaaattt
    45661 gggacgagaa ctgggttatc agctcccaag tggagctgga acggcttctg acaaggtggc
    45721 tagccagatt ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt
    45781 taaaaacact gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa
    45841 tttcttaaaa gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat
    45901 ctttttttgg agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg
    45961 cgaaattctc ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggttgccca
    46021 tgaggaagat ggcaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat
    46081 tcgttacgaa aatgataaac tttacatcaa tgacaaagaa acggacgagc cttatctagc
    46141 agactatatc aaacgcttca aggatgacaa actccaaagc acttactcag gcaagggctt
    46201 tgaaggaaat aaaggaactt tctttagaag tatcgctcaa aaagcccaag ccttcacagt
    46261 tgatgtcaac tacaacacca actttagctt tactgttcca gaaggagaat accttctcct
    46321 cggagatgac cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga
    46381 tatcacaggg gaagctaaat tccgcttctg gccaatcacc cgtatcggaa cattttaaga
    46441 gacctaagag gccgagaatc accaatctca gcctcttctt ctatcgtgag aagtgattgt
    46501 ttattgacaa atactcaatg aaaatcaaag aacaaactag gaagctagcc gtaggctgct
    46561 taaaacagtg ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa tactgttttg
    46621 aggttgcaga tggaagctga cgtggtttga agatattttc gaagagtata aaataaaaac
    46681 aatcccaact ctcacctatt catgcaaagg aattttatgg aagtttattt ttcaggaacc
    46741 attgaacgga ttatttttga aaatcccagc aatttttatc gcatcctcct cctagaaatc
    46801 gacgatacgg acgcagagga ttttgatgac tttgaaatca ttgtcacagg aaccatggct
    46861 gatgtaattg agggcgaaga ctatactttt tgggggcaaa ttgtccagca ctccaagtat
    46921 ggagaacaac tgcaaatcag tcgttatgat cgcgcaaaac caactagtaa gggcttggtc
    46981 aagtactttt caagtagcca tttcaagggg attggtctca agacagctca gaaaatcgtg
    47041 gatacctatg gcgaaaatac cattgacgaa attttgcaac acccagaaaa gttagaaggc
    47101 atcgcaggac tctctgccaa aaatcgcgag gctttcgtct ccactctccg tctcaactac
    47161 ggaacggaga tggttttggc caaactagcc aactacggca ttcccaacaa actagccttt
    47221 cagattcaag acttttacaa ggaagaaacc cttgatgtgg ttgaaaatta tccctaccag
    47281 ctggttgagg atatcaaggg tttgggcttt accattgctg accaactagc tgaggaacta
    47341 ggcatcgaaa gtcaggctcc tgaacgcttc cgcgccggtc tagttcacag tctttttcag
    47401 gcctgtatgg aaacagggga cacctatgtt gaagcacggg atttgctgga acaaaccctt
    47461 actctccttg agtcttcccg tcccgtagaa ctagacccca gccaagttgc ccaagagctc
    47521 tcctacctga tcgaagaaga caaggttcag cagattgata ccaagatctt tgacaacagc
    47581 ctctttttcg ctgaggaagg catccgcagt cacttggttc gtatccttga aaaaggaaaa
    47641 cagaagagtc atgatttaga aaccattcaa aaacatatca ctactatcga ggaagagctg
    47701 ggaattgagt atgataacat tcaaaaacag gctatctgtg atgctatcca gaataaggtc
    47761 tttatcctga caggtggacc tggtactggt aagacaactg ttatcaatgg gatcatcgct
    47821 gtttacgccc tgttagaggg acttgacctc aggaagaaaa gcaatctgcc cattcttctt
    47881 gctgctccaa ctggacgagc cgctcgccgc atgaatgaat tgacaggttt gcctagcgcg
    47941 accatacacc gccacttggg aatgacaggt gacgatgata ccagtcatct ggaagattac
    48001 ctagatgctg actttatcat cgtggatgaa ttctctatgg tggatacttg gctggccaat
    48061 caactcttct ccaatatctc ttctaacagt aagatcctca tcgtaggtga cagtgatcag
    48121 ctaccttctg tcagtcctgg acaggttcta gcggatctgc ttcatattcc tttgattcct
    48181 cagactcgct tggaaaaaat ttatcgacaa agcgaagaat caaccatcgt caccctagct
    48241 agtcagattc gacagggcat cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc
    48301 tactttgaaa ttgctagtgg ccatattcct gccaccattg aaaaaatctt aggtgccgcc
    48361 ctcagaaatg gtattcctgc ccgtgatatc caagttctgg ctcctatgta ccgagggacg
    48421 gcagggattg atgctatcaa tcagctcatg caagacctgc tcaatccccc acaaaaagat
    48481 caactcagtt ttgaagctcc tcagtgccac tatcgtaagg gagacaaggt cattcatttg
    48541 gttaacgatg ctgaaatcaa tgtctttaat ggggatttag gagctatcac agacctgatt
    48601 cctggtaaat acaccgaatc gaaacaagac gagattgtca ttgattttga tggtaatgaa
    48661 gtctcttacc cccgtaacga atggtacaag attcgcttgg cctatgccat gagtattcat
    48721 aagtctcagg gaagtgagtt cccagttgtc atcctaccga ttactagtgc tagccgacgt
    48781 atgctggagc gaaatctcat ctacacagcc attacacgtg ccaaaagcaa actcatctta
    48841 ctaggcgaat tacaagcctt cgactatgct acccaacaca tcggaactgc ccgaaaaacc
    48901 tatctgattg aacgcttcag tgatctactg gagaatgttg aagaaaagca acaagctgtc
    48961 tctgaaacag tcacatcaag tgcctctgaa caatcctaca tcctaaccga agaaaactgg
    49021 gacagcattc cagccatgat tgggattaca gacacagacc tcaaagagat ttttggaaaa
    49081 tagtacatca gaaaacccac caattcaggt gggttttctg tttattaaga ttattttact
    49141 gttgctgtgc ttgtaatcaa ttcaacagct tttttgattg tgatatcatg tttcaacatg
    49201 tcagctgaaa gcaagctttg tacttgagca acttccatgt tgtagtctgc tgccaattgc
    49261 tcaacttctt tttggatttc ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct
    49321 tcgataacaa ggttagtctt agtacgtgac tcagcttctg cttggtattg gttgtgaagg
    49381 tcttcttgag tagttccagt gatttggaag tacatgtcag ggttgatccc ttgacgttgc
    49441 aagttcccaa ggaattcatt tactgaacgg tgaacttctt catggatcat ttcttctgga
    49501 agttctacga tttcagcgtt ttctacagct gtatcaattg ctgcaccttc aactgcatct
    49561 ttgtaagctt cttctttagc agcagccaat tctttgcggt atttttcttt caagtcagca
    49621 agtgtttcaa cttcttcatc aatgtctttt gcaagttcat cgtcaagagc tggaacttct
    49681 ttagctttta cttcgtggat agttgtcacg aatttagctt ctttacctgc aaggtcttct
    49741 gcttggtagt cttctgggaa tgttacgata acatcaacgg tttcgccagc tgagtgacct
    49801 accaattggt cttcgaaacc agggatgaat tgacctgaac caagtccaag tgagaagttt
    49861 tcaccttttc caccgtcaaa ttcaacaccg tcgatagaac caacgaagtc gatcacaaca
    49921 gtgtcgccgt tttcagcagc agcttccttg ataaccaatt cagccaggtt gttgcgttcg
    49981 cgttcgatac gctcttcaac atcagcgtca gttacttctt tttctacatc aactgatact
    50041 tcaaggtttt tgtagtcacc caattttact tcaggttttg taacgacttc agcagcgata
    50101 acccagtctt gacctttttc cattgaagtt acgtcaattt ttggttgggc aaccacttca
    50161 agaccagctt cttttacagc tgcttcataa gcgtttggca aaagagcgtt cattgcatct
    50221 tgataaagag cttcttcacc aaatttttgg tcgaagatag ggcgtggaag gtgaccttta
    50281 cggaaacctg gaacattaag agatttcttc actgacttga agacacggtc caattctggt
    50341 ttgatttggt cttgagagat agtgaaagtc aagacaccac ggtttgtttc tttgttttca
    50401 aatgatacag acattctgtc atttctcctt aaaatttttt aaatacagtc tattataaca
    50461 ttttctataa ataaaatcta gactaatgca gccaattata gacaacaagc ctttttccta
    50521 actaaaacac tcataaagta tagacaattt tagactactt tggatatctt ttggttagtc
    50581 attttccaaa actaatttat ctaatttttc agttatatag tagattgaaa ctagaatagt
    50641 acacctctac ttctaaaaca tttttagaaa tcgatttgac tgtcccgatc gatttgtcct
    50701 gttcttgttt cattttacta tatagatcgc attcgaaaga attcgttcca aaattgcttg
    50761 gttcgttctt ctcttggacg actaaagaat tgatgggcat tatttttttc aacaattttc
    50821 ccactgtcca taaaaataac atgatgggct acatctctag caaaacctat ctcataaagc
    50881 tgatcaaaaa ctcaatctga ggagaaaatc caataaggct ttccataata aaggacatcc
    50941 tatcaagatt tttgaacacc cgataggctg cctttttccg attttgaaga ctttttgtcc
    51001 agcttctttt accttataaa taacaacaaa aatcaaagac aagctagaaa gattaccgca
    51061 gataactcaa acagtgtttt gaggttgcag ataagactga cggagtcagc tcaaagcact
    51121 gctttgaggt tgtagataga actgacgaag tcagtaacat atgcctaaga caaagcgatg
    51181 ctaacctgat ttgaagagat tttcgaaaaa gattaaatat actctacaat ttgctcaatc
    51241 aattcttggt cgtctaaacc tgtaacttgt ataacaacat ctttgactga ttgtttagcc
    51301 aacaattcac ctaatcgaat actttcttca tcatttacat cgcgatagtc aaaggcatag
    51361 ccaactgttt taagtaggtt tttatatgac aaactgagtt ctttcaattc acgtatcggc
    51421 cggatgaatc gttcattata gcctaatttt cggattggag tgcgagctac gcgactaacc
    51481 tcgtccgcta tgaaagggtt ttcaaaccgt tctataatga ctttgtgata attctccaat
    51541 tcttttttat caaagttcca tttggcaatc aagagactcc gaatttcagc taatacagat
    51601 tcaatccgag atttgatatt aggattttga agagcttcca aaattgtctt ggcaccataa
    51661 tgcgcaccaa tgtaagctga agttgcatgt ccagaattga ctgaaaaaag ttttcgctca
    51721 ataaagggtt ctaaatcttc ttcataatgc acatctttta gacgtaaatc tggattttta
    51781 agacgcttgg tttccacgac ccattcatta aagggctcga ccacaacaaa aagggaatct
    51841 tcgtgacttt gtgctggaac aatcctgtct actgcagcat ttggaaaacc tatgtagtta
    51901 tcagcaaatg tcaaaccttc cggacttaaa tatttcttga cttcttgata aagaaattga
    51961 gacccgccaa tcatattttc acaggccata acatccaatg cctgtgtatt tcctgcaact
    52021 cggcgagctt cgattccttt ggctagaagt tcggcgataa aagggagtat attaggtccg
    52081 attgcagtag taataatatc cgtcttttga atcgcttcaa tgacttgctc aggatgttct
    52141 ttgctattaa tgccagccac attagttact tctatacgag actgtccttt ctgtgcaatt
    52201 tcaatttcat acttgccctt ttcatttaga gcatgaatta tctgattatt gacatccaca
    52261 aaatcaatat ggaaaccatt tttaaataga atttcaccta taaaaccacg accgatatta
    52321 ccggcaccaa aatgaacaga atgtttcatt caatttctcc ttttcctatt tgagggacat
    52381 atatactaga tgacaaatga cgaaattcaa ttattcaaca gcatcaaata agcgcaatac
    52441 ttcctctttt gactgagcat ctgctagttt aagaacatta tctacatctg cacagaagat
    52501 agaaattttc tgaataattt ctaagtgttc attaccaata ccagcaatac caaaaagaac
    52561 cgttgccact tgagggttag atacattccc aaaatcaacc cctataggga cttgaacgac
    52621 tgtaatacca gacttgagga catccttttt tgctgcatct gttccatgcg gtatggcgat
    52681 aaagttaccc atgtaaacag atagctcttt atctcgctca atcatggctt caatatagtc
    52741 ttcattaaca tatccaccct cataaagaac ttgcccacaa taacaaatag cttcctcctt
    52801 gttagaaaat tgtttattaa gcttaatcaa atgtttttca agtttcatat tagttctcca
    52861 atttcttaat tttttcgtta aaaatagtat ttagcatctg ataaataatg gattgatttc
    52921 ccgtcttgta aatctctgta taaagatgat tttcaataat cgactgacta atagctgtca
    52981 ttaaatctct cgcttcctcg ctagcttctt tagacattag cattagcaga caccttttga
    53041 cctcttcttc ctctcgtttc attgacaatg cggagatagg tagtttgagt tcaaacatag
    53101 taaaactatt tgttgttact ttgctagact gactatgtaa aagcaccaga ccagtattag
    53161 gaatagccat aggactattc tggaagtgag ataacaattt tcttgttagg taatctctgt
    53221 cactcacatt cttctgatat tggatgattt gttctaccgt gtgctcaaat gattgattat
    53281 tctccaattg aaccaactcg aattgactca aaagctgact actagatatt aaataatctt
    53341 gcaagtcata acttttctct ggagcgatag catcacgcgc gacaattgca cgatgtgcct
    53401 gtacatactg aagtcgttcc tgtaattcaa gcaattcttt gacggttgga aaactagaaa
    53461 ttacatcgat ttcctgatta gtcagcggct tggtagataa aatataatca tactgactga
    53521 gatcaatact gtggtaatct actagagact gaatatctat caactctaca aaaggagcaa
    53581 cactcttaat tttactgact aataaatctc tagtgacccg acgttcatcc gttaaaagca
    53641 aaacacggac tggataaatc tctggactac ggcctaagct agagataaaa tgtagggcaa
    53701 tcatgccata ctcatactct gtatgaagat atttcggaaa aatatcattc actaaaagac
    53761 tgatgactgt ataaagaaat ttattccttt caactaaaat ctggacagat tctggcaaat
    53821 tttcaccctg aaaaaggata gggacgccta aactgagccg aatatgatgg aaaagaaaat
    53881 tgaataaaac cttgtcctta aaaaagtcaa tcttggtata catggaaacc gtatcaatca
    53941 gatttgaaat attgtagaaa aattcaccat caaatttctc cgtaaagagc ggattgtcct
    54001 gacgtttaat gattaattca tccaagatgc tcgcaaaata gataatttcc tgaatactat
    54061 aaaattgtgc agtctgctta gagtaagctt gaaaaatttt ttgagaaatt tccaaagcct
    54121 gcttactagt attaggtgaa ttttcaatgt tttgctcctg acctataaga gataacaaga
    54181 tcgcaaaaaa catcttcatc ctagcatcca tatctggaaa acctgacagt tgcttattaa
    54241 caatctgact ggccagccta gttctatctg cttctaaaat atcaaagctc ccaaaattac
    54301 cggttgaaaa atctgctact gagatacagt ttgtcagtaa aatagccaaa aatcttctct
    54361 taccaactga atcaccagaa atccgataac ctttttgtcg ttcaattttc agatcaaagt
    54421 ctaaaagacg cttatcaata tctgaaatat cctgaataat agttacatta ctgactttcg
    54481 tgcactcttg caatgcttca ttggtgacaa aaccactctc agtcagaagg cgataggtaa
    54541 tcaactcttg tctttcttgg ggactatact caactaacac ttcaagttct gtcggcaaat
    54601 catccaactc tccagtcaaa atatagtatt tcccatgctt cgttatttcg attccatatt
    54661 gctccatgct atctgtcaaa tctgataaag ttcgataaat tgttctagat gaaacctgta
    54721 agatttcagt catatcttgc attgaaagct tccctacatg taggaaagcc ttcaataatt
    54781 gttcttctcg tttggttaat agcattcgta atttagaaac ctctagttct atttgtacat
    54841 tctagcagcc attttgtcat attctggtgt tgttactaaa ctatccacaa taagaaattg
    54901 agaattcggt gctgcttgct gcacttctgc ctgtaaagaa atagttgtta caatcattat
    54961 gtttttagaa ttaaattcac ctaattctga aattttggca gtagaaactg gaatacgaat
    55021 attcttgttt ctaaagatag cccgaatcgt ttcacagccc atagttgcag ttccctgtgc
    55081 tttaccataa gcaactacta cagcatcaat atggttaagg tcaatttcct gactatctac
    55141 tggtgctgaa gttggtatat ctccttcaat ttctgctatt ggagaagctc ctgttaatga
    55201 agctacaatt tcatcataac gaggggaccc taagaaatta tcaacagaaa catgaatagc
    55261 acttggactc ttgtctttag ctcttggtgt cagttcttcc tgagtaacaa ttaatgtttt
    55321 tggtgtatca agcaaatttg agattgcctg attagatact ggaatctcta gacctgcttt
    55381 tttaacctta tctcgaagaa tactagctcc catagcagag cttcccatac cagcatcgca
    55441 ggcgaaaatg attttttcca ctgagtctgt cgaaacaact gcatcaacag aagttgatac
    55501 taactgacct ttagactgag ccttagctgc ttgggtagcc gcctgagcag cttcgagcga
    55561 atcctcagtt gacttgtctg catgaagaat aagggctgct acaaggaaag aaacaactgc
    55621 tgccactaaa acacctaaaa gaacatttag atggggccaa acaccttttg gcgccgtagc
    55681 cataatcgca ataatagaac ctggtgaagc tggagattta agaccagcgt ctaagagttg
    55741 aaaagtaaaa gttccagaga tacctcctgc catagcagct aaaaatagag taggcttcat
    55801 cataacataa ggaaagtaaa tttcatgaat ccctccgaag aaatgaataa ccattgcccc
    55861 ccaagaagaa gatttagcag aacctttacc gaatacagca taagctaata gaattcccag
    55921 gcctggtcca ggattagctt ccaataggaa gagaattgac ttaccagctt gagctacctg
    55981 ttctactccc agaggagtaa aaatgccatg attgagggca ttattgagga aaaggacttt
    56041 agccggttcg atgataatat tagccatagg aaggaggcga gcattgacaa tagcctcaac
    56101 accattccca acagctccag taagagtcga tacgactgga ccgattgcgt agaaagccaa
    56161 aagcaataat gcaaaaccaa cgagaccagc tgagaagtta ttaactaaca tttcaaatcc
    56221 gggacgaatt ttttcttgga acttctcatc aaatttcttg atagtccatc ctcccagtgg
    56281 gcccattacc atagctccga taaacatagg aacactagaa cctgtaattg caccaacagt
    56341 agcaatagct cctacaacgg caccacgttg gccatggatc atatatccac ctgtgtaacc
    56401 aatcaggatt ggcaataaat acgttaacat aggaccaaca acagtagcta actgttcatt
    56461 tggcagatag ccatcagcga taaagagggc agtcaatact ccccaagcaa taaatgctcc
    56521 aatattgggc ataaccatat ttgaaagcga tgtccctagt ttttgaaccc tgactttcaa
    56581 tgatactttt tcttccatta gatcatcctc cttttcttaa aactagtata tacaaagtta
    56641 aaaaccttta aaactaaagt tttgtcacag attttgtgtc aaaacattac ttttgacgag
    56701 gctgggcaaa aaggcttaaa aattataaaa cgcatcatat caggtgtaca tgaact
//
LOCUS       DBEJNA010000010        55462 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEJNA010000010 DBEJNA010000000
VERSION     DBEJNA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 55462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.10"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            134..994
                     /gene="speE"
                     /locus_tag="ACL3JB_000673"
     CDS             134..994
                     /gene="speE"
                     /locus_tag="ACL3JB_000673"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0685458.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            991..2250
                     /locus_tag="ACL3JB_000674"
     CDS             991..2250
                     /locus_tag="ACL3JB_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0685459.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTRIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDAINFNGQDIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            2250..3377
                     /gene="nspC"
                     /locus_tag="ACL3JB_000675"
     CDS             2250..3377
                     /gene="nspC"
                     /locus_tag="ACL3JB_000675"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0685460.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            3374..4459
                     /gene="aguA"
                     /locus_tag="ACL3JB_000676"
     CDS             3374..4459
                     /gene="aguA"
                     /locus_tag="ACL3JB_000676"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0685461.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            4469..5344
                     /gene="aguB"
                     /locus_tag="ACL3JB_000677"
     CDS             4469..5344
                     /gene="aguB"
                     /locus_tag="ACL3JB_000677"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0685462.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(5525..6334)
                     /locus_tag="ACL3JB_000678"
     CDS             complement(5525..6334)
                     /locus_tag="ACL3JB_000678"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0685463.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            6606..6827
                     /locus_tag="ACL3JB_000679"
     CDS             6606..6827
                     /locus_tag="ACL3JB_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0685464.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            6881..7552
                     /locus_tag="ACL3JB_000680"
     CDS             6881..7552
                     /locus_tag="ACL3JB_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0685465.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNIYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(7603..7800)
                     /locus_tag="ACL3JB_000681"
     CDS             complement(7603..7800)
                     /locus_tag="ACL3JB_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0685466.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            7793..8701
                     /locus_tag="ACL3JB_000682"
     CDS             7793..8701
                     /locus_tag="ACL3JB_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0685467.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            8698..9159
                     /gene="lspA"
                     /locus_tag="ACL3JB_000683"
     CDS             8698..9159
                     /gene="lspA"
                     /locus_tag="ACL3JB_000683"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0685468.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            9149..10036
                     /locus_tag="ACL3JB_000684"
     CDS             9149..10036
                     /locus_tag="ACL3JB_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0685469.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            10039..11922
                     /gene="cbpE"
                     /locus_tag="ACL3JB_000685"
                     /gene_synonym="pce"
     CDS             10039..11922
                     /gene="cbpE"
                     /locus_tag="ACL3JB_000685"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0685470.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AISLESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     ATETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            12023..13132
                     /gene="proB"
                     /locus_tag="ACL3JB_000686"
     CDS             12023..13132
                     /gene="proB"
                     /locus_tag="ACL3JB_000686"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0685471.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            13142..14404
                     /locus_tag="ACL3JB_000687"
     CDS             13142..14404
                     /locus_tag="ACL3JB_000687"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0685472.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            14408..15205
                     /gene="proC"
                     /locus_tag="ACL3JB_000688"
     CDS             14408..15205
                     /gene="proC"
                     /locus_tag="ACL3JB_000688"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0685473.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            15321..15959
                     /gene="tmk"
                     /locus_tag="ACL3JB_000689"
     CDS             15321..15959
                     /gene="tmk"
                     /locus_tag="ACL3JB_000689"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0685474.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            15956..16846
                     /locus_tag="ACL3JB_000690"
     CDS             15956..16846
                     /locus_tag="ACL3JB_000690"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0685475.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            16886..17203
                     /gene="yabA"
                     /locus_tag="ACL3JB_000691"
     CDS             16886..17203
                     /gene="yabA"
                     /locus_tag="ACL3JB_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0685476.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            17206..18075
                     /gene="rsmI"
                     /locus_tag="ACL3JB_000692"
     CDS             17206..18075
                     /gene="rsmI"
                     /locus_tag="ACL3JB_000692"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0685477.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            18137..18265
                     /locus_tag="ACL3JB_000693"
                     /pseudo
     CDS             18137..18265
                     /locus_tag="ACL3JB_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            18302..18820
                     /locus_tag="ACL3JB_000694"
     CDS             18302..18820
                     /locus_tag="ACL3JB_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0685478.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            18929..19576
                     /locus_tag="ACL3JB_000695"
     CDS             18929..19576
                     /locus_tag="ACL3JB_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGR0685479.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(19565..20369)
                     /locus_tag="ACL3JB_000696"
     CDS             complement(join(19565..19999,20001..20369))
                     /locus_tag="ACL3JB_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGR0685480.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNFIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            20346..20618
                     /locus_tag="ACL3JB_000697"
     CDS             20346..20618
                     /locus_tag="ACL3JB_000697"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0685481.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            20812..22146
                     /gene="trmFO"
                     /locus_tag="ACL3JB_000698"
     CDS             20812..22146
                     /gene="trmFO"
                     /locus_tag="ACL3JB_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0685482.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            22230..22967
                     /gene="pyrH"
                     /locus_tag="ACL3JB_000699"
     CDS             22230..22967
                     /gene="pyrH"
                     /locus_tag="ACL3JB_000699"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0685483.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            22976..23533
                     /gene="frr"
                     /locus_tag="ACL3JB_000700"
     CDS             22976..23533
                     /gene="frr"
                     /locus_tag="ACL3JB_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0685484.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            23593..24447
                     /gene="cvfB"
                     /locus_tag="ACL3JB_000701"
     CDS             23593..24447
                     /gene="cvfB"
                     /locus_tag="ACL3JB_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0685485.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKFRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            24456..24671
                     /locus_tag="ACL3JB_000702"
     CDS             24456..24671
                     /locus_tag="ACL3JB_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0685486.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            24757..25725
                     /locus_tag="ACL3JB_000703"
     CDS             24757..25725
                     /locus_tag="ACL3JB_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0685487.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            25918..26418
                     /locus_tag="ACL3JB_000704"
     CDS             25918..26418
                     /locus_tag="ACL3JB_000704"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685488.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            26421..26747
                     /locus_tag="ACL3JB_000705"
                     /pseudo
     CDS             26421..26747
                     /locus_tag="ACL3JB_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035616.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(27048..28159)
                     /gene="ald"
                     /locus_tag="ACL3JB_000706"
                     /pseudo
     CDS             complement(27048..28159)
                     /gene="ald"
                     /locus_tag="ACL3JB_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            28336..28759
                     /locus_tag="ACL3JB_000707"
                     /pseudo
     CDS             28336..28759
                     /locus_tag="ACL3JB_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            28827..29477
                     /locus_tag="ACL3JB_000708"
     CDS             28827..29477
                     /locus_tag="ACL3JB_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0685489.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELNKVSGIGAKTIEKLKDYVTVD"
     gene            29461..31701
                     /locus_tag="ACL3JB_000709"
     CDS             29461..31701
                     /locus_tag="ACL3JB_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0685490.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSTSYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPGPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLIAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            31880..32068
                     /locus_tag="ACL3JB_000710"
     CDS             31880..32068
                     /locus_tag="ACL3JB_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685491.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            32100..32687
                     /locus_tag="ACL3JB_000711"
     CDS             32100..32687
                     /locus_tag="ACL3JB_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685492.1"
                     /translation="MLNITHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNISAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            32691..33871
                     /locus_tag="ACL3JB_000712"
                     /pseudo
     CDS             32691..33871
                     /locus_tag="ACL3JB_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     misc_feature    34031..34162
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            34178..34708
                     /gene="infC"
                     /locus_tag="ACL3JB_000713"
     CDS             34178..34708
                     /gene="infC"
                     /locus_tag="ACL3JB_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0685493.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            34741..34941
                     /gene="rpmI"
                     /locus_tag="ACL3JB_000714"
     CDS             34741..34941
                     /gene="rpmI"
                     /locus_tag="ACL3JB_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0685494.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            34993..35352
                     /gene="rplT"
                     /locus_tag="ACL3JB_000715"
     CDS             34993..35352
                     /gene="rplT"
                     /locus_tag="ACL3JB_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0685495.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            35410..35790
                     /locus_tag="ACL3JB_000716"
     CDS             35410..35790
                     /locus_tag="ACL3JB_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0685496.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            36040..36840
                     /locus_tag="ACL3JB_000717"
     CDS             36040..36840
                     /locus_tag="ACL3JB_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0685497.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            36851..37789
                     /locus_tag="ACL3JB_000718"
     CDS             36851..37789
                     /locus_tag="ACL3JB_000718"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0685498.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFVFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            37831..39864
                     /locus_tag="ACL3JB_000719"
     CDS             37831..39864
                     /locus_tag="ACL3JB_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGR0685499.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYADNEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGVFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(39925..41580)
                     /gene="pavA"
                     /locus_tag="ACL3JB_000720"
     CDS             complement(39925..41580)
                     /gene="pavA"
                     /locus_tag="ACL3JB_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0685500.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            41685..42182
                     /gene="ybeY"
                     /locus_tag="ACL3JB_000721"
     CDS             41685..42182
                     /gene="ybeY"
                     /locus_tag="ACL3JB_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0685501.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            42163..42558
                     /locus_tag="ACL3JB_000722"
     CDS             42163..42558
                     /locus_tag="ACL3JB_000722"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0685502.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            42575..43474
                     /gene="era"
                     /locus_tag="ACL3JB_000723"
     CDS             42575..43474
                     /gene="era"
                     /locus_tag="ACL3JB_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0685503.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            43523..44347
                     /gene="mutM"
                     /locus_tag="ACL3JB_000724"
     CDS             43523..44347
                     /gene="mutM"
                     /locus_tag="ACL3JB_000724"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0685504.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            44347..44952
                     /gene="coaE"
                     /locus_tag="ACL3JB_000725"
     CDS             44347..44952
                     /gene="coaE"
                     /locus_tag="ACL3JB_000725"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0685505.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            44939..46138
                     /locus_tag="ACL3JB_000726"
     CDS             44939..46138
                     /locus_tag="ACL3JB_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGR0685506.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYLVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            46138..46287
                     /gene="rpmG"
                     /locus_tag="ACL3JB_000727"
     CDS             46138..46287
                     /gene="rpmG"
                     /locus_tag="ACL3JB_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0685507.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            46327..46560
                     /gene="secG"
                     /locus_tag="ACL3JB_000728"
     CDS             46327..46560
                     /gene="secG"
                     /locus_tag="ACL3JB_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0685508.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            46662..49016
                     /gene="rnr"
                     /locus_tag="ACL3JB_000729"
     CDS             46662..49016
                     /gene="rnr"
                     /locus_tag="ACL3JB_000729"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0685509.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTIIQTVIKTSFRMTYSDVNDILAVDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            48979..49446
                     /gene="smpB"
                     /locus_tag="ACL3JB_000730"
     CDS             48979..49446
                     /gene="smpB"
                     /locus_tag="ACL3JB_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0685510.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            49462..50322
                     /gene="tehB"
                     /locus_tag="ACL3JB_000731"
     CDS             49462..50322
                     /gene="tehB"
                     /locus_tag="ACL3JB_000731"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0685511.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            50395..51348
                     /gene="coiA"
                     /locus_tag="ACL3JB_000732"
     CDS             50395..51348
                     /gene="coiA"
                     /locus_tag="ACL3JB_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR0685512.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHIANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGKKLWLKERLTCLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIK
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            51367..53169
                     /gene="pepF"
                     /locus_tag="ACL3JB_000733"
     CDS             51367..53169
                     /gene="pepF"
                     /locus_tag="ACL3JB_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0685513.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYAYLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            53171..53884
                     /locus_tag="ACL3JB_000734"
     CDS             53171..53884
                     /locus_tag="ACL3JB_000734"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0685514.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            53951..54892
                     /gene="prsA"
                     /locus_tag="ACL3JB_000735"
     CDS             53951..54892
                     /gene="prsA"
                     /locus_tag="ACL3JB_000735"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0685515.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(55011..55352)
                     /locus_tag="ACL3JB_000736"
                     /pseudo
     CDS             complement(55011..55352)
                     /locus_tag="ACL3JB_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        16658 a        10140 c        12598 g        16066 t
ORIGIN      
        1 gctgtggtta gagcctttcg gaaatcgtca agcgattgga ggaaatgaac taatccacag
       61 tggcttattc caagtatacc acttgggctt tggcagtagc taactgcgct aaatataata
      121 taaggagaaa tagatggatt tatggttttc tgaagttcat actccagatg tcaaattgtc
      181 tctgagaaca gccaagcaac tttacgctgg aaaaagtgaa tggcaggata tcgaagtctt
      241 ggatacgcca gcttttggga aaatactgat tttaaatggg catgttttgt tttcagatgc
      301 ggatgatttt gtctacaatg aaatgaccgt ccacgttccc atggctgtcc acccaaatcc
      361 aaagaaagta ttggttattg gaggtggtga cggcggtgtt gcccaagtat taacactcta
      421 tcctgagctg gaacaaatcg acattgtgga accagatgag atgttggttg aagtctgtcg
      481 tgagtatttc ccagattttg ccgcagggct agatgatcct cgtgttacca tttattatca
      541 aaatgggcta cgctttttgc gaaactgcga agatgactac gatattatca tcaacgatgc
      601 gacagatcca tttggccata cggaagggct ctttaccaag gaattttacg gtaatagtta
      661 tcgagctcta aaggaagatg gtatcatgat ttatcagcat gggagtccct tctttgatga
      721 ggatgagtca gcttgccgaa gcatgcatcg caaggttaat caagcctttc caatcagtcg
      781 ggtctatcag gcccatatcc caaccagtcc agctggctat tggttgtttg gatttgcatc
      841 aaaaaaatac caccctgtca aagattttga caaggaaggc tggaaaaaac gtcagctttt
      901 cacagaatac tacactgcaa acttacacgt gggagccttt atgttgccca agtatgttga
      961 ggacatttta gaagaagagg aaggaaaaaa atgagtcgtt tactagttat tggatgtggg
     1021 ggcgttgccc aagttgctat ttcaaagatt tgtcaagata gcgaaacctt tacagagatt
     1081 atgattgcta gccgtactaa gtcaaaatgt gatgacttga aagctaaact ggaaggcaaa
     1141 acaagtacaa ggattgagac agcagctctt gatgctgata aggttgaaga agtgattgcc
     1201 ctgattgaaa gctacaaacc agaagctgtg ttgaacgtag ctttgcctta tcaagacttg
     1261 accatcatgg atgcttgctt ggcaacaggt gttcactata tcgatacagc caactacgag
     1321 gctgaggata cagaagaccc tgagtggcgt gctatttatg aaaaacgttg caaggaactt
     1381 ggttttacag cctactttga ctactcatgg caatgggctt atcaggagaa attcaaagaa
     1441 gctggcttga ccgctctgct tggttctggt tttgacccag gtgtgactag tgttttctcg
     1501 gcttatgccc tcaaacacta ttttgatgaa atccactata tcgacatttt agactgtaat
     1561 ggtggtgacc acggttatcc atttgcgaca aactttaacc cagaaatcaa tctacgcgag
     1621 gtttctgcgc caggttctta ctgggaagat ggaaaatggg tcgaggttga agccatgtct
     1681 atcaagcgcg agtacgattt ccctcaagtt ggacaaaaag acatgtatct ccttcaccac
     1741 gaagaaatcg aatcattggc taagaacatt ccaggtgtta aacgtattcg tttctttatg
     1801 acctttggtc aatcttactt gacgcacatg aaatgtcttg aaaatgttgg actccttcgt
     1861 acagatgcta ttaacttcaa cggtcaagac attgttccga ttcaattctt aaaagccttg
     1921 cttccagacc ctgcaagcct tggcccgcgc actgttggta aaaccaatat cggttgtatc
     1981 tttacaggtg tcaaggacgg tgttgaaaag accatctata tctacaatgt ttgcgaccat
     2041 caggaatgtt acgcagaagt tggttcacaa gctatttctt acacaacagg cgttccagcc
     2101 atgattggga caaaattagt tatgaacggt acttggaaac aagctggagt gtataacctt
     2161 gaggagttag atccagatcc attcatggaa gctttgaatg agtatggttt gccatgggtt
     2221 gtggttgaaa atccacaaat ggtggactaa tgaagttaga acaagtacca acaccagcct
     2281 atgttattga cttggccaag ttagaagcta attgccgcat tctacaatat gtacaagaag
     2341 aggccggttg caaggtcttg cttgcccaga aggcatattc cctctacaaa acttatccct
     2401 tgattagcca gtatctatca ggtacgacag ctagtggact ctatgaggcc aaattggcaa
     2461 gggaagaatt tcctggtgaa gtccatgttt ttgcaccagc tttcaaggat gaggacatgg
     2521 aggaattgct tgggataaca gaccatatcg tctttaactc agagagacag ttgcgtaagc
     2581 atggttcgcg ttgtcgagag gctggtgtca gtgttggttt gcgcctcaac cctcagtgtt
     2641 caactcaagg agatcacgcg ctctatgacc cttgtgcacc tggttctcgc tttggagtta
     2701 ctatagacaa gattccgagt gatttgctag atttggttga cggacttcat tttcataccc
     2761 tttgcgagca gggagcagat gatttacaaa caactttgaa agcagtagaa gaacagtttg
     2821 gtccctactt acatgaggta aaatggctca atatgggtgg tggtcatcat attacaagag
     2881 aaggttacga tgtggatttg ctgatttcag aaatcaagcg tatccgaaaa acttacaatc
     2941 ttgaaatcta tatcgagcct ggtgaagcca ttgcgcttaa tgcgggttat ttagcaactg
     3001 aggtattaga tattgtagaa aacggtatgg aaatcttggt tttagacgcc tctgcgacct
     3061 gccatatgcc tgatgtactt gagatgccct atcgtccacc tttgagaaat ggctttgagt
     3121 cacaggaaaa agcccatacc tacagacttt cttctaatac ctgtctgact ggcgatgtga
     3181 ttggtgatta tagttttgaa aatccagtcc aaatcggaga cagactttat tttcaagaca
     3241 tggccattta ttcttttgtc aaaaataata cctttaatgg tattggattg ccaagtctct
     3301 atctcatgga cgaacaggga gactgtagct tactcaaagc ttttggctat caagacttta
     3361 aagggagatt atcatgatgg acagtccaaa aaaattaggc tatcacatgc cagcagagta
     3421 cgaaccccat catggtaccc tcatgatatg gccgactcga ccaggatcat ggccttttca
     3481 aggaaaggct gctaaaagag catttactca gatcatcgag accatagcag aaggggaaag
     3541 agtctatctt ttggtggagc aggcctatct atctgaagcc caatcctatc ttggagacaa
     3601 ggttgtttat ttagacattc ccaccaatga tgcctgggcg cgtgatactg gcccaaccat
     3661 tctcgtcaat gataaaggta agaaattagc cgtggattgg gccttcaatg cttggggagg
     3721 cacctatgat ggtctttatc aagattatga agaggatgac caagtagcca gtcgttttgc
     3781 tgaggccttg gaaaagcctg tctatgatgc taaacctttt gtactggaag gaggcgcaat
     3841 ccatagcgat ggtcaaggaa ctattctcgt aactgaaagt tgcttgctta gtcctggtcg
     3901 caatcctaac ctgactaaag aggagattga aaacacatta ttagaaagtc ttggtgctga
     3961 aaaagttatt tggcttcctt atggtattta tcaggatgaa accaatgaac acgtcgataa
     4021 tgttgctgcc tttgttggtc ctgctgagct tgttttggct tggacagatg acgaaaatga
     4081 tccccagtat gccatgtcaa aagcagatct cgaactctta gaacaggaaa cagatgcaaa
     4141 aggttgtcac ttcaccattc ataaattgcc tatccctgca gttcgacaag ttgtgacaga
     4201 agaagatttg ccaggctaca tctatgaaga aggagaagaa gagcgatacg caggtgaacg
     4261 actagcagct tcctacgtaa acttttatat cgccaacaag gctgtcttgg ttccacagtt
     4321 tgaggatgta aacgaccaag tggccttaga tatcctcagc aagtgtttcc cagaccgtaa
     4381 agttgtcgga ataccagcca gagatattct cttaggtggt ggcaatatcc actgtatcac
     4441 ccaacaaatt ccagaatagg agaaaaagat gagaaatgta agagttgcaa ccattcagat
     4501 gcaatgcgct aaggatgtgg caacaaatat ccaaaccgca gagcgtttag tacgtcaggc
     4561 tgctgagcaa ggagcccaaa ttattctctt gcccgagttg tttgaacatc cctatttctg
     4621 tcaggaacgt cagtatgact actaccagta tgcccaatct gtagcggaaa atactgccat
     4681 tcagcatttt aaggtgattg ctaaggaact acaagttgtt ttaccaatca gtttctatga
     4741 aaaagatggt aatgtcttgt ataactctat tgccgtcatt gatgcagatg gggaagtgct
     4801 gggcgtttat cgaaagaccc atataccaga tgaccattat tatcaagaaa aattctattt
     4861 cacgcctggt aacactggtt tcaaggtctg gaatactcgc tatgctaaga ttggtatcgg
     4921 tatctgttgg gatcaatggt tccctgaaac agcccgctgt cttgcattga atggtgctga
     4981 attgctcttt tatcctacag ctatcggttc agagccaatt ttggatacag atagttgtgg
     5041 tcactggcaa cgtactatgc aagggcacgc agcagcgaat attgttccag tcatcgcagc
     5101 caatcgttat ggtttagagg aggttactcc tagtgaggaa aatggcggac agagttccag
     5161 tcttgacttc tacggttcct cctttatgac ggatgaaaca ggagctattc tagaacgagc
     5221 tgaaagacaa gaagaagctg ttctgttagc tacttatgac ctagacaagg gagcaagtga
     5281 acgtctaaac tggggcttgt ttcgagatag aagaccagaa atgtatagac aaattacaga
     5341 ttagtgtggg agaaatgaga gattcattct gctagactaa cttcttatta gcaactataa
     5401 gatactatgg catctagtaa atcgattttt atgattcgct attcttgtct attgattagt
     5461 ccgtatttta aaatattagc aaaaaagcaa atagcagtaa cttctgtcta tttgcttttc
     5521 ttttttatag aatatatttc tcaatagcac gcgcaacgcc gtcttcttcg ttgcttgagg
     5581 taacggcatc cgcaagagat ttgacataat cgctggcatt tcccattgca atcccaagcc
     5641 ctgcaaactg gagcatttcg atatcgttat tagcatcgcc catggccata atctctgagg
     5701 aatcaatctt caaaatctca gctagtcgtg aaagagcagt agcctttgtc gttccaagcg
     5761 gcattgcttc ataaatgaca ggctgcgaac gaactccact gaatcgttgg caaagctctt
     5821 cagcaaaacg ctgctcaaaa tcgtctgttt gttcttttgt tcctaaaaac ataccttgga
     5881 acatccggaa ctttccacta gtcgcttctt caagagaaat ttcagtcagg tctgaaaata
     5941 ctagtttagc atcattttca ataacttgat tgggtttgcc accgagaaca aaataatgtg
     6001 actcgtcaaa aagtgtcaac tgaacatcac tcttttcagc aaggtcatag aggtattcga
     6061 tgtcagctgg actcagttct ttccagtcaa ctagactcca atcactggtc tggtgagttg
     6121 aacaaccgtt gttaacaata atatattcgt tctggaggtc aagctccagt tttttgtagt
     6181 aggggaggac accgaaaagg gggcgacccg tacagagaac cagtttgaca cctttttcaa
     6241 tggctttgtg aatagcagta atgtgagctt gtgggatttc cttggcttca ttgaggaggg
     6301 tgccgtccat atccaaggct agtagtttaa tcataggtct tccttcttta tcttttggta
     6361 gtattatagc atattttgga gaagaaattg atagaaagct tgagactaat tgattttata
     6421 gtttaagatg ttttgatgac aattcatgat ttgaagagga tatttcgcaa agatatgcta
     6481 tactatgttt gtcaatgttg caactagaca aattaaaaaa ccaacttaat ataatagttt
     6541 ttttgtaagt aggtatgagt atcagattac tcaactaatc tgaagaataa tggaggaaat
     6601 atatcatgat tttaatgaca aaaaatataa atctaacaaa tgaagaatta gagctgatac
     6661 aaggtggagc agattcatat ggtaaaaatc ctaatggtag gtacgattgg gaaatagaac
     6721 cagtattaac tctgccggtt catggatttt gtcccagagg cacctatgat ttaggatata
     6781 ttggaggagg caatcatctt tgcaaaggaa gtgctgcgag attttaagta aaatttatta
     6841 gtaatatgaa gaaacaagtg gagaaagcag agaatttaat atgaaaaaac gggctattca
     6901 aattttacta gcattgtcct taatttttta caaatcaact tggttttgga gagttttcaa
     6961 tcacctcgca aagccctatc taccagcaag tcgtgaattt tttcagattc tgcttttgat
     7021 ggagagcgga gttcttttct tagcggtcat ctatctactg gtttttgcag gaaagaaaat
     7081 ttttcatttc aagtggcagc tgaggtactt catctacctt ttactgggct acatcatttc
     7141 atatatgtct gacttcctct tttcgtattt catatccctg tcttcaaatc agatttcttt
     7201 gaatgaaacg gtagaaatga tggggagaca ggagttccct tatttcttgc tcatcgtttg
     7261 cttcatcgcc cctattgctg aggaattgat ttatcgcggt gtgcttatga caaccttttt
     7321 caaaaactcg ccttggtacg gagatgtctt gctttctgct attattttcg gttatattca
     7381 tatcaatttt gctttaactc ctcttgcttt tttcatttat gctagcggag gtcttatttt
     7441 ggctctattg tatcgcatga ctaaaaacat ctactatcca atactagttc atattctcat
     7501 caatatcact gccttctggg atgtttggtt actcctattt tcaggaagtt agcttactaa
     7561 aaaatgtcgg aattttccgg cattttcttt tttcacaaat agtcaacgtt tttctttccg
     7621 atactgaagt ggtgtgtagc cacttatttt tttgaattga ttttgaaaat aagattggcg
     7681 tgagaaaggc agatagtgaa gatagttaag aagaatagga tgttcttttt tcctttttgg
     7741 aaaacttcta aaatatggta taatgaaaag ataaagaagt tgggggtaga agatgaacat
     7801 tcaacaatta cgctatgttg tggctattgc caatagtggt acttttcgtg aagctgctga
     7861 aaagatgtat gttagtcagc cgagtctgtc tatttctgtt cgtgatttgg aaaaagagtt
     7921 gggctttaag attttccgtc ggaccagctc agggactttc ttgacccgtc gtgggatgga
     7981 attttatgaa aaagcgcaag aattggttaa aggatttgat atttttcaaa atcagtatgc
     8041 caatcctgaa gaagaaaaag atgaattttc cgttgctagc cagcactatg acttcttgcc
     8101 accaactatt acggcctttt cagagcgcta tcctgactat aagaacttcc gtatttttga
     8161 atcaactact gttcaaatat tagatgaagt ggcgcaaggg catagtgaga ttgggattat
     8221 ctacctcaac aatcaaaata aaaaggggat tatgcaacgg gttgaaaagt taggtctgga
     8281 ggtcatcgaa ttgattcctt tccataccca tatttatctc tgtgagggtc atcctttagc
     8341 ccagaaagag gaattagtca tggaggattt agcggattta ccaacggttc gtttcactca
     8401 agagaaagac gagtaccttt attattcaga gaactttgtc gataccagcg ctagctcaca
     8461 gatgtttaat gtgacagacc gtgccacctt gaatggtatt ttggagcgga cggacgccta
     8521 tgcgacaggt tctggatttt tagatagtga cagtgttaat ggcattacag ttattcgtct
     8581 caaggataac ctagataacc gcatggtcta tgttaaacgt gaagaagtgg agcttagtca
     8641 agctgggact ctcttcgtag aagtcatgca agaatatttt gatcaaaaga ggaaatcatg
     8701 aaaaaaagag caatagtggc agtcattgta ctgcttttaa ttgggctgga tcagttggtc
     8761 aaatcctata tcgtccagca gattccactg ggtgaagtgc gctcctggat tcccaatttc
     8821 gttagcttga cctacctgca aaatcgaggt gcagcctttt ctatcttaca agatcagcag
     8881 ctgttattcg ctgtcattac tctggttgtc gtgataggtg ccatttggta tttacataaa
     8941 cacatggagg actcattctg gatggtcttg ggtttgactc taataatcgc gggtggtctt
     9001 ggaaacttta ttgacagggt cagtcagggc tttgttgtgg atatgttcca ccttgacttt
     9061 atcaactttg caattttcaa tgtggcagat agctatctga cggttggagt gattatttta
     9121 ttgattgcaa tgctaaaaga ggaaataaat ggaaattaaa attgaaactg gtggtctgcg
     9181 tttggataag gctttgtcag atttgtcaga attatcacgt agtctcgcga atgaacaaat
     9241 taaatcaggc caggtcttgg tcaatggtca agtcaagaaa gctaaataca cagtccaaga
     9301 gggtgatgtc gtcacttacc atgtgccaga accagaggta ttagagtatg tggctgagga
     9361 tcttccgcta gaaatagtct accaagatga ggatgtggct gtcgttaaca aacctcaggg
     9421 aatggttgtg cacccgagtg ctggtcatac cagtggaacc ctagtaaatg ccctcatgta
     9481 tcatattaag gacttgtcgg gtatcaatgg ggttctgcgt ccagggattg ttcaccgtat
     9541 tgataaggat acgtcaggtc ttctcatgat tgctaaaaac gatgatgcgc atctagtact
     9601 tgcccaagaa ctcaaagata aaaagtctct ccgcaaatat tgggcgattg ttcatggaaa
     9661 tctgcctaat gatcgtggtg taattgaagc gccgattggc cggagtgaaa aagaccgtaa
     9721 gaaacaggct gtaactgcta aagggaagcc tgcagtgacg cgttttcacg tcttggaacg
     9781 ctttggcgat tatagcttag tagagttgca actggagaca gggcgcactc atcaaatccg
     9841 tgtccacatg gcttatatcg gccatccagt cgctggtgat gaggtctatg gtcctcgcaa
     9901 gactttgaaa ggacatggac aatttcttca tgccaagact ttaggtttta ctcatccgag
     9961 aacaggtaag accttggaat ttaaagcaga tatcccagag atttttaagg aaaccttgga
    10021 gagattgaga aagtaagaat gaaaaagaaa ttaactagtt tagcacttgt aggcgctttt
    10081 ttaggtttgt catggtatgg gaatgttcag gctcaagaaa gttcaggaaa taaaatccac
    10141 tttatcaatg ttcaagaagg tggcagtgat gcgattagtc ttgaaagcaa tggacatttt
    10201 gccatggtgg atacaggaga agattatgat ttcccagatg gaagtgattc tcgttatcca
    10261 tggagagaag gaattgaaac gtcttataag catgttctaa cagaccgtgt ctttcgtcgt
    10321 ttgaaggaat tgagtgtcca aaaacttgat tttattttgg tgacccatac ccacagtgat
    10381 catattggaa atgttgatga attactgtct acctatccag ttgaccgagt ctatcttaag
    10441 aaatatagtg atagtcgtat tactaattct gaacgtctat gggataatct gtatggctat
    10501 gataaggttt tacagactgc tacagaaaca ggtgtttcag ttattcaaaa tatcacacaa
    10561 ggggatgctc attttcagtt tggggacatg gatattcagc tctataatta tgaaaatgaa
    10621 actgattcat cgggtgaatt aaagaaaatt tgggatgaca attccaattc cttgattagc
    10681 gtggtgaaag tcaatggcaa gaaaatttac cttgggggcg atttagataa tgttcatgga
    10741 gcagaagaca agtatggtcc tctcattgga aaagttgatt tgatgaagtt taatcatcac
    10801 catgatacca acaaatcaaa taccaaggat ttcattaaaa atttgagtcc gagtttgatt
    10861 gttcaaactt cggatagtct accttggaaa aatggtgttg atagtgagta tgttaattgg
    10921 ctcaaagaac gaggaattga gagaatcaac gcagccagca aagactatga tgcaacagtt
    10981 tttgatattc gaaaagacgg ttttgtcaat atttcaacat cctacaagcc gattccaagt
    11041 tttcaagctg gttggcataa gagtgcatat gggaactggt ggtatcaagc gcctgattct
    11101 acaggagagt atgctgtcgg ttggaatgaa atcgaaggtg aatggtatta ctttaaccaa
    11161 acgggtatct tgttacagaa tcaatggaaa aaatggaaca atcattggtt ctatttgaca
    11221 gactctggtg cttctgctaa aaattggaag aaaattgatg gaatctggta ttattttaac
    11281 aaagaaaatc agatggaaat tggttgggtt caagataaag agcagtggta ttatttggat
    11341 gttgatggtt ctatgaagac aggatggctt caatatatgg ggcaatggta ttactttgct
    11401 ccatcagggg aaatgaaaat gggctgggta aaagataaag aaacctggta ctatatggat
    11461 tctactggtg tcatgaagac aggtgagata gaagttgctg gtcaacatta ttatctggaa
    11521 gattcaggag ctatgaagca aggctggcat aaaaaggcaa atgattggta tttctacaag
    11581 acagacggtt cacgagctgt gggttggatc aaggacaagg ataaatggta cttcttgaaa
    11641 gaaaatggtc aattacttgt gaacggtaag acaccagaag gttatactgt ggattcaagt
    11701 ggtgcctggt tagtggatgt ttcgatcgag aaatctgcta caattaaaac tacaagtcat
    11761 tcagaaataa aagaatccaa agaagtagtg aaaaaggatc ttgaaaataa agaaacgagt
    11821 caacatgaaa gtgttacaaa tttttcaact agtcaagatt tgacatcctc aacttcacaa
    11881 agctctgaaa cgagtgtaaa caaatcggaa tcagaacagt agtagaaaag aaggttttag
    11941 ggccttcttt ttcctatcaa ctcttttcta tttcctgtta ttcatgttat aatggataaa
    12001 tatgaataat cggagtgaga ctatgaaata caaacggatt gtctttaagg tgggtacttc
    12061 ttctctgaca aatgaggatg gaagtttatc acgtagtaag gtaaaggata ttacccagca
    12121 gttggctatg ctgcacgagg ctggtcatga gttgattttg gtgtcttcag gtgccattgc
    12181 ggctggtttt ggagccttag gatttaaaaa gcgtccgact aaaattgctg ataaacaggc
    12241 ttcagcagcg gtagggcagg gacttttgtt ggaagaatat acgaccaatc ttctcttgcg
    12301 tcaaatcgtt tctgcacaaa tcttgctgac ccaagatgac tttgtggata agcgtcgtta
    12361 taaaaatgcc catcaggctt tgtcggtttt gctcaaccgt ggggcaattc ctatcatcaa
    12421 tgagaatgat agtgtcgtta ttgatgagct caaggttggg gacaatgaca ctctaagtgc
    12481 tcaagtagcg gcgatggtcc aagcagacct tttagttttc ttgacagatg tggacggtct
    12541 ctatactgga aatcctaatt cagatccaag agccaaacgc ttggagagaa tcgagaccat
    12601 caatcgtgag attattgata tggctggtgg agctggttcg tcaaacggaa ctgggggtat
    12661 gttaaccaaa atcaaggctg caactatcgc gacggaatca ggagttcctg tttatatctg
    12721 ctcatccttg aaatcagatt ccatgattga ggcggcagag gagaccgagg atggttctta
    12781 ctttgttgct caagagaagg ggcttcgtac ccagaaacaa tggcttgcct tctatgctca
    12841 gagtcaaggt tctatttggg ttgataaagg ggctgcggaa gctctctctc aacatggaaa
    12901 gagtcttctc ttatctggta tcgttgaagc agaaggagtc ttttcttacg gtgatatcgt
    12961 gacagtattt gataaggaaa gtggaaaatc acttggaaaa ggacgcgtgc aatttggagc
    13021 atctgctttg gaggatatat tgcgttctca aaaagccaag ggtgtcttga tttaccgtga
    13081 cgactggatt tccattactc ctgaaatcca actacttttt acagaatttt agaggtaaac
    13141 tatggtgagt agacaagaac aatttgaaca ggtacaggct gttaaaaaat cgattaacac
    13201 agctagtgaa gaagtgaaaa accaagcctt gctagccatg gctgatcact tagtggctgc
    13261 tactgaggaa attttagcgg ctaatgccct cgatatggca gcggctaagg ggaaaatctc
    13321 agatgtgatg ttggatcgtc tttatttgga tgcagatcgt atagaagcga tggcaagagg
    13381 aattcgtgaa gtggttgcct taccagatcc aatcggtgaa gttttagaaa caagtcagct
    13441 tgaaaatggt ttggttatca caaaaaaacg tgtagctatg ggtgtcatcg gtattatcta
    13501 tgaaagccgt ccaaatgtga cgtctgatgc ggctgctttg actcttaaga gtggaaatgc
    13561 ggttgttctt cgtagtggta aggatgccta tcaaacaacc catgccattg tcacagcctt
    13621 gaagaagggc ttggagacga ctactattca tccaaatgtg attcaactgg tggaggatac
    13681 tagccgtgaa agtagttatg ctatgatgaa ggccaagggc tatctagacc ttctcattcc
    13741 tcgtggagga gctggcttga tcaatgcagt agttgagaat gcgattgtac ctgttatcga
    13801 gacagggact gggattgtcc atgtctatgt ggataaggat gcagacgaag acaaggcgct
    13861 gtctatcatc aacaatgcta aaaccagtcg tccttctgtt tgtaatgcca tggaggttct
    13921 gctggttcat gaaaacaagg cagcaagcat ccttcctcgc ttggatcaaa tgctggttgc
    13981 agagcgtaag gaagctggac tggaaccaat tcaattccgc ttggatagca aagcaagcca
    14041 gtttgtttca ggtcaagcag ctgagaccca agactttgac accgagtttt tagactatgt
    14101 ccttgctgtt aaggttgtga gcagtttaga agaagcggtt gcgcacattg aatcccacag
    14161 cacccatcat tcggatgcta ttgtgacgga aaatgctgaa gctgcagcat actttacaga
    14221 tcaagtggac tctgcagcgg tgtatgttaa tgcctcaact cgtttcacag atggaggaca
    14281 atttggtctt ggttgtgaaa tggggatttc tactcagaaa ttgcacgcgc gtggtccaat
    14341 gggcttgaaa gagttgacca gctacaagta tgtggttgct ggtgatgggc agataaggga
    14401 gtaagagatg aagattggat ttatcggttt ggggaatatg ggtgctagct tggcaaaatc
    14461 tgtcttgcag actaggacgt cagatgagat tctccttgcc aatcgtagtc aagctaaggt
    14521 agatgctttc attgcagact ttggtggtca ggcttccagc aatgaagaaa tgtttgcaga
    14581 agcagatgtg atttttctag gagttaagcc tgctcagttt tctgaactgc tttctcaata
    14641 ccagaccatc cttgaaaaaa gagaaagtct tcttttgatt tcgatggcag ctggattgac
    14701 cttagaaaaa ctagcaagtc ttatcccaag tcaacaccga attattcgta tgatgcctaa
    14761 tacccctgct tctatcgggc aaggagtgat tagttatgcc ttgtctccta attgcagggc
    14821 tgaggacagt gagctctttt gtcagctttt atccaaggct ggtctcttgg ttgaattagg
    14881 agaaagctta atcaatgcag cgacaggtct tgcaggctgt ggaccagcct ttgtctatct
    14941 ctttattgag gctttggcag atgcaggtgt tcagacggga ttaccacgag aaacagcctt
    15001 gaaaatggca gcccaaactg tggtaggagc tgggcaattg gtcctagaaa gccagcaaca
    15061 tcctggagtt ttgaaagatc aagtttgtag tccaggcggt tcgactattg ctggcgtagc
    15121 aagcttagaa gcgcatgctt ttcgaggcat agtcatggag gcagttcatc aagcctataa
    15181 acgaacacaa gaactaggta aataagaggt agctttgact gcctctttta tggtggctga
    15241 aatgagaaga cacaaaaaga ttgtcacaaa ctcctatttt tttgatagaa tagaagtagt
    15301 aaaaaagaaa tgagttagac atgtcaaaag gatttttagt ctctcttgag ggaccagagg
    15361 gagcaggcaa gaccagtgtt ttagaggctc tgctaccaat tttagaggaa aaaggagtag
    15421 aggtgctgac gacccgtgaa cctggcggag tcttgattgg ggagaagatt cgggaagtga
    15481 ttttggatcc aagtcatact cagatggatg ctaaaacaga gctacttctc tatattgcca
    15541 gtcgcagaca gcatttggtg gaaaaagttc ttccagccct tgaagctggc aagttggtca
    15601 tcatggatcg ttttatcgat agttctgttg cctatcaggg atttggtcgt ggcttagata
    15661 ttgaagccat tgactggctc aatcagtttg cgacagatgg cctcaaaccc gatttgacac
    15721 tctattttga catcgaggtg gaagaagggc tggctcgtat tgctgctaat agtgaccgcg
    15781 aggttaatcg tttggatttg gaagggttgg acttgcataa aaaagttcgt caaggctacc
    15841 tttctcttct ggataaagag ggaaatcgca ttgtcaagat tgatgctagt ctccctttgg
    15901 agcaagttgt ggaaactacc aatgctgtct tgtttgacgg aatgggcttg gccaaatgaa
    15961 acaagatcaa ctaaaggctt ggcaaccagc tcagtttgac cgttttgtcc gtatcttaga
    16021 acaagaccag ctcaatcacg cctatctctt ttcaggtttc tttggaagct tggaaatggc
    16081 gcaattttta gctaagagcc ttttttgtac ggataaagtt ggcgtcttac catgtgagaa
    16141 atgccgaagt tgcaagctga ttgaacagga agagtttcca gatgtcacct tgattaagcc
    16201 agtcaatcag gtcatcaaga cagaacgcat tcgggaattg gtgggacagt tttctcaagc
    16261 agggattgaa agccagcaac aggtctttat catcgagcaa gcggataaaa tgcatcccaa
    16321 cgcagccaat tctctgctca aggtcatcga agaaccccag agtgaagttt atattttctt
    16381 cttgactagc gatgaggaaa agatgttacc gacaatccga agtcggactc agatcttcca
    16441 ctttaaaaag caagaagaaa aacttatctt actcttagaa caaatgggac ttgttaagaa
    16501 aaaagcgact cttttagcta agtttagtca atcgcgagct gaagcagaaa agttggcaca
    16561 tcaggcaagt ttttggacct tggtcgatga aagtgaacgc ctgctgactt ggttagtagc
    16621 taagaaaaaa gaaagttatc tacaggttgc caaattagcc aacttggcag atgataagga
    16681 aaaacaggat caggttttac ggattcttga agttctctgt gggcaggacc tcttgcaggt
    16741 aagagtaaga gtgattctac aagatttact agaagctaga aaaatgtggc aagctaatgt
    16801 cagctttcaa aatgccatgg aatatctggt cttgaaagaa atataaactc aaaaatgaat
    16861 gataaagaaa ggaaagggct gttttatgga caaaaaagaa ttatttgacg cgctggatga
    16921 tttttcccaa cagttattgg taaccttggc cgatgtggaa gccatcaaga aaaatctcaa
    16981 gagcctggta gaggaaaata cagctcttcg tttggaaaat tctaagttgc gagaacgctt
    17041 gggtgaggtg gaagcagatg ctcctgtcaa ggccaagcat gttcgtgaaa gtgtccgtcg
    17101 catttaccgt gatggatttc acgtatgtaa tgatttttat ggacaacgtc gagagcagga
    17161 cgaggaatgt atgttttgtg acgagttgct atacagggag taggcatgca gattcaaaaa
    17221 agttttaagg ggcagtctcc ctatggcaag ctgtatctag tggcaacgcc gattggcaat
    17281 ctagatgata tgacctttcg agctatccag accttgaaag aagtagattg gattgctgct
    17341 gaggatacgc gcaatacagg tcttttgctc aagcattttg acatttccac caagcagatc
    17401 agttttcatg agcacaatgc caaggaaaaa attcctgatt tgattggttt cttgaaagca
    17461 gggcaaagta ttgctcaggt ctctgatgcc ggtttgccta gcatttcaga ccctggtcat
    17521 gatttagtta aggcagctat tgaggaagaa attgcagttg tgacagttcc aggtgcctct
    17581 gcaggaattt ctgccttgat tgccagtggt ttagcgccac agccacatat cttttacggt
    17641 tttttaccga gaaaatcagg tcagcagaag caattttttg gcttgaaaaa agattatcct
    17701 gaaacacaga ttttttatga atcacctcat cgtgtagcag acacgttgga aaatatgtta
    17761 gaagtctacg gtgaccgctc cgttgtcttg gtcagggaat tgaccaaaat ctatgaagaa
    17821 taccaacgag gtactatctc tgagttatta gaaagcattg ctgaaacgcc actcaagggc
    17881 gaatgtcttc tcattgttga gggtgccagt cagggtgtgg aggaaaagga cgaggaagac
    17941 ttgttcgtag aaattcaaac ccgcatccag caaggtgtga agaaaaacca agctatcaag
    18001 gaagtcgcta agatttacca gtggaataaa agtcagctct acgctgccta ccacgactgg
    18061 gaagaaaaac aataaaggga gacaggatgt aataattctg tctgtttctg tttaacttaa
    18121 ttagtgatga taatataaag atgtatcact tggtatagaa gctttggtat taagtttttt
    18181 attaagccca tacggaatac cgatggttgg agcagcagtt atagcgttct tagaaggtat
    18241 aaatagaaaa ataaggtcat tttaaatcaa aggattgata aatcagaaag aaggtgattt
    18301 tttgcgaaca tacgaaaata aagaagaact aaaagctgag atagagaaaa catttgagaa
    18361 atatatttta gaatttgata atattccaga aaatttaaaa gataagagag ctgatgaagt
    18421 tgacagaact ccagcagaaa accttgctta tcaggttggt tggaccaact tggttcttaa
    18481 atgggaagaa gatgaaagaa aggggcttca agtaaaaaca ccatcggata aatttaaatg
    18541 gaatcaactt ggtgaattat atcagtggtt cacagatacc tacgctcatt tatctctgca
    18601 agagttgaaa gcaaaattaa atgaaaatat taattctatc tctgcaatga ttgattcgtt
    18661 gagtgaggaa gaattatttg aaccgcatat gagaaagtgg gctgatgaag cgactaaaac
    18721 agcgacttgg gaagtgtata agtttattca tgtaaatacg gttgcacctt ttggaacttt
    18781 cagaactaaa attagaaaat ggaagaagat agtattataa attatatttt taactttaaa
    18841 aaatttcata aaaatggtta ccaaaggcga tagaagaaaa actatcgtct ttttctttgc
    18901 aaatttttaa gaagggaggt gatcttgcat ggactttgaa tatttttata acagagaagc
    18961 ggaaagattt aacttcttaa aagtaccgga gatattagtt gatagagaag aatttcgggg
    19021 cttatcagca gaagcaatta tcctttattc catacttctt aaacagacag gaatgtcatt
    19081 taagaataac tggatagaca aggaaggcag agtatttatc tattttactg tcgaagaaat
    19141 tatgaaaaga agaaatatct caaagccaac tgccataaaa acattagatg agcttgatgt
    19201 aaaaaaagga ataggactga tcgaaagagt aaggcttgga cttggtaagc cgaacatcat
    19261 ttatgttaaa gactttatga gtatatttca ggtaaaagaa aatgacttac agaagtcaaa
    19321 aaacttaact tcagaagtaa aagattttaa cctcagaagt aaagaaaatg aacttcaaga
    19381 ggttaagaac cttgactcta actatataga gaataataag agtaagtata gtaagagaga
    19441 atatagtttt ggtgaaaacg gacttggaac atttcaaaat gtgtttttag ctgctgaaga
    19501 tatatcggat ttacaaatca taatgaactc acagcttgag aattacatta gacttcctgc
    19561 aaaactagaa tcctagttca tgattgataa taccagcact caaattcatt cgtaatccga
    19621 agcgtttacg atgatttcga taggttgttg aaaacatttt aaacgttttt actttggcaa
    19681 agatattctc aaccttgctt ctctccttag atagcgcatg attacaggct ttatcttcaa
    19741 ctgttagcgg cttgagtttg ctggatttac gtggagtttg tgcttgagga tatatcttca
    19801 tgagcccttg ataaccactg tcggccaaga ttttaccagc ttgtccgata tttctgcaac
    19861 tcattttgaa caacttcata tcatgactat agttcacagc gatatccaaa gaaacaattc
    19921 tcccttgact tgtgacaatc gcttgagcct tcatagcgtg aaatttcttt ttaccagaat
    19981 gattcgctaa ttcttttttt agggcgattg atttgtactt ccgtcgcatc aatcattacc
    20041 gtgtcctcag aactgagagg agttcttgaa atcgtaacac cactttgaac aagagttact
    20101 tcaacccatt ggctccgacg gataaagttg ctttcgtgaa taccaaaatc agccgcaatt
    20161 tgttcataag ttcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg
    20221 cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca
    20281 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
    20341 gttagttgtt tacttgcttc atcattcata gaactactat accatatttt gtttcgcagg
    20401 aagtctattg gaaagtaaga aatattgaag ctgaggctat tagaagaaat tgtgagcgtg
    20461 gtgctatttt ttcaggtaaa ataaaatatc acgaagattc acagtttaaa ggagatcact
    20521 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
    20581 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
    20641 aatactcact atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
    20701 tttttttgtt atactagtag aagaaaaaat tagaaagatt tgtgggtgtc aaacagccca
    20761 gtggggtgtt ttaatatgga cttaggtccc acccaaagag gtattagtgt cgtgtctcaa
    20821 tcttatatca atgttatcgg tgctggtttg gcaggttctg aagcagctta ccaaatcgca
    20881 gagcgtggta ttccagttaa actatatgaa atgcgtggtg tcaagtctac accccagcat
    20941 aaaacagaca attttgctga gttggtttgt tccaattctt tgcgtgggga tgctttgaca
    21001 aatgcagttg gtcttctcaa ggaagaaatg cgtcgcttgg gttctgttat cttggaatct
    21061 gctgaggcta cacgtgttcc tgcaggtggt gcccttgcag tggaccgtga tggtttctct
    21121 caaatggtga ccgaaaaagt tgccaaccac cccttgattg aagtggttcg tgatgaaatt
    21181 acagaattgc cgacagatgt tattacggtt atcgctactg gtcctttgac aagtgatgcc
    21241 ttggctgaaa agattcatgc ccttaataat ggcgatggct tctatttcta cgatgcagca
    21301 gcgcctatta tcgatgtcaa cactatcgat atgagtaagg tctatctcaa atctcgttat
    21361 gataagggag aagcagccta tctcaatgct ccaatgacca agcaagagtt tatggatttc
    21421 catgaagcct tggtcaatgc ggaagaagca ccgctcaatt cttttgaaaa agaaaagtac
    21481 tttgaaggat gtatgccaat cgaagttatg gccaaacgtg gcattaaaac tatgctttat
    21541 ggccctatga agccagtcgg tcttgagtat ccggacgact acacaggacc tcgtgatgga
    21601 gaatttaaaa caccttatgc ggttgtgcaa cttcgtcagg ataatgcagc tggtagccta
    21661 tacaatattg ttggtttcca gacccacctc aaatggggag aacaaaagcg tgtcttccaa
    21721 atgattccgg gtcttgaaaa tgcggagttt gtccgttatg gtgtcatgca tcgcaattct
    21781 tacatggatt caccaaatct tcttgagcag acttaccgtt ccaagaaaca accaaatctc
    21841 ttctttgctg gtcagatgac gggggtggaa ggctatgttg agtcggcggc ttcgggctta
    21901 gttgcgggaa ttaacgcagc tcgtctcttc aaggaagaaa gcgaggttat tttccccgag
    21961 acgacagcga ttggaagctt agctcattac attacccatg ccgacagcaa acatttccaa
    22021 ccaatgaatg tcaattttgg gatcatcaag gagttggaag gcgagcgtat ccgtgataag
    22081 aaggctcgtt atgaaaaaat tgcagagcgt gcccttgccg acttagagga atttttgact
    22141 gtctaatttt tttgaaagaa ttgttcatga tactataaaa atcttagaaa ttgtgataaa
    22201 ataggtagga tgaaagaagg agagtgaaaa tggcgaatcc caagtataaa cgtattttaa
    22261 tcaagttatc aggtgaagcc cttgccggtg aacgtggcgt agggattgat atccaaacag
    22321 ttcaaacaat cgcaaaagag attcaagaag ttcatagctt aggtatcgaa attgcccttg
    22381 ttattggtgg aggaaatctc tggcgtggag aacctgcagc agaagcaggt atggaccgtg
    22441 ttcaggcaga ttacactgga atgcttggga ctgttatgaa tgctcttgtg atggcagatt
    22501 cattgcaaca agttggggtt gatacgcgtg tacaaacagc tattgctatg caacaagtgg
    22561 cagagcctta tgtccgtgga cgtgcccttc gtcaccttga aaaaggccgt atcgttatct
    22621 ttggtgctgg aattggttca ccatacttct cgacagatac aacagcggcc cttcgtgcag
    22681 ctgaaatcga agcagatgcc atcctcatgg ctaaaaatgg cgtcgatggt gtgtacaatg
    22741 ccgatcctaa gaaggacaag acagccgtta agtttgaaga attgacccac cgtgatgtta
    22801 tcaacaaagg tcttcgtatc atggactcaa cagcctcaac cctctcaatg gacaacgaca
    22861 ttgacttggt tgtcttcaac atgaaccaat caggcaacat caaacgtgtc gtatttggtg
    22921 aaaatatcgg aacaacagtt tcaaataata tcgaagaaaa ggaataagaa agaatatggc
    22981 taacgtaatt attgaaaaag ctaaagagag aatgacccag tctcaccaat cacttgctcg
    23041 tgaatttggt ggtatccgtg ctggtcgtgc caatgcaagc ttgcttgacc gtgtacatgt
    23101 agaatactat ggagtcgaaa ctcctcttaa ccaaatcgct tcaattacga ttccagaagc
    23161 gcgtgttttg ttggtaacac catttgacaa gtcttcattg aaagacatcg aacgtgcctt
    23221 gaacgcttct gatcttggta tcacaccggc taatgacggt tctgtgattc gcttggttat
    23281 cccagctctt acagaagaaa ctcgtcgtga ccttgctaaa gaagtgaaga aggtcggcga
    23341 aaatgctaaa gtggctgtcc gcaatatccg tcgcgatgct atggacgaag ctaagaaaca
    23401 agaaaaagca aaagaaatca ctgaagacga attgaagact cttgaaaaag acattcaaaa
    23461 agtaacagac gatgctgtta aacacatcga cgacatgact gctaacaaag agaaagaact
    23521 tttggaagtc taaaaataaa cagaaaaact cagttggcat tgctggctga gttttattcg
    23581 aaagaaggaa atatgaatac aaatcttgca agttttatcg ttggactgat catcgatgaa
    23641 aacgaccgtt tttactttgt gcaaaaggat ggtcaaacct atgctcttgc taaggaagaa
    23701 ggccaacata cagtagggga tacggtcaaa ggttttgcat acacggatat gaagcaaaaa
    23761 ttccgcctga caaccttaga agtgactgcc actcaggacc aatttggttg gggacgtgtc
    23821 acagaggttc gtaaggactt gggtgtcttt gtggatacag gccttcctga caaggaaatc
    23881 gttgtgtcac tcgatattct ccctgagctc aaggaactct ggcctaagaa gggcgaccaa
    23941 ctctacatcc gtcttgaagt agataagaaa gaccgtatct ggggcctctt ggcttatcaa
    24001 gaagacttcc aacgtcttgc tcgtcctgct tacaacaaca tgcagaacca aaactggcca
    24061 gccattgttt accgtctcaa gctgtcagga acttttgttt acctaccaga aaataatatg
    24121 cttggtttta ttcatcctag cgagcgttac gcagagccac gtttggggca agtattagat
    24181 gcgcgcgtta ttggtttccg tgaagtggac cgcactctga acctctccct caaaccacgc
    24241 tcctttgaaa tgttggaaaa cgatgctcag atgattttga cttatttgga aagcaatggc
    24301 ggtttcatga ccttaaatga caagtcatct ccagacgaca tcaaggcaac ctttggcatt
    24361 tctaaaggtc agttcaagaa agctttaggt ggtcttatga aggctggtaa aatcaagcaa
    24421 gaccagtttg ggacagagtt gatttaggga ggcttatgag aaaatcattt tacacttggc
    24481 tcatgaccga gcgcaatcct aaaagtaaca gtcccaaagc aattttggca gacctcgctt
    24541 ttgaagaggc agcttttcca aaacatacag atgattttga tgaggtcagt cgctttttgg
    24601 aggagcatgc cagtttctct tttaacctag gagattttga cagcatttgg caggaatatc
    24661 tagaacacta gcatttattc attgggtttg ggctagtaat ttctccatcc ctctgctata
    24721 ataaaaagaa ataaaaggat tagagaggtt ctttatttga aggaacattc aatagacatt
    24781 caactgagtc atccagatga cctgtttcat ctttttggtt ccaatgaacg ccatcttcgt
    24841 ttgatggaag aagagcttga tgttgtgatt catgctcgta cggagattgt ccaggttttg
    24901 ggagaagagt ctgcctgtga ggaagcccgt caagttattc aggctttgat ggtcttggta
    24961 aatcgtggga tgaccgttgg tacgccagat gtagtcactg cgattagcat ggtcaaaaac
    25021 gatgaaattg ataagtttgt cgccctttac gaagaagaaa ttatcaagga taatactggg
    25081 aaaccgatcc gcgtcaaaac cttaggtcaa aaactttatg tggacagtgt caaacagcat
    25141 gatgtgacct ttggaattgg gcctgcaggg acggggaaga cctttcttgc agttactttg
    25201 gcagtgactg cccttaaacg tgggcaagtc aagcggatta tcttgacacg tccagcggtg
    25261 gaagcaggag agagtctagg ttttcttccg ggtgatctta aggagaaggt agatccttac
    25321 cttcgtcctg tttacgatgc cttgtatcag attctgggga aagaccaaac gactcgtctc
    25381 atggagcgtg aaattatcga aattgcgccc cttgcctata tgcgtggtcg gaccttggat
    25441 gatgcctttg tcattctcga tgaggcgcaa aacacgacca tcatgcagat gaagatgttc
    25501 ttgacgcgtt taggctttca ttctaagatg attgtcaatg gagatatcag tcagattgac
    25561 ctgccacgca atgtcaagtc aggtttgatt gatgcccaag agaaactcaa gaacatccat
    25621 cagattgact ttgttcattt ttcagctaag gatgtggttc gccatccagt tgtcgctcag
    25681 attatccgag cttatgaata ttctactgaa gttgcacacg actgattttg aggaagttcg
    25741 cctgcaaaag aatatacttt tgagagagga aaatccagtt gtataggcta aaggttttat
    25801 ccaaaggttt gagacaacga ttaggcacga tggaaagaac ttttatgtgg ctgatgacga
    25861 tcagtgcatc ttcctgtgtc ataatcacag ggcacaagaa agtaggaatt tgaaaagatg
    25921 attgaccaac tatctaagta ttacagttgt aggatactaa ctgaaaagga tattccaagt
    25981 attttatctt tatatgaaag taatcctctg tattttcagc attgtccacc agaaccaaat
    26041 tttgcaactg taaaagagga catgctttgt ctacctgaag gtaaagctaa ggctgataag
    26101 ttttttgttg gattttggaa tggatctgac cttgtggctg ttatggattt tgtctatgca
    26161 tatcctgatg aggagactgt ttttattggt ttgtttatgg ttgatcaagc ctatcagagg
    26221 aaagggattg gtagtcatat tgtgacagaa gcactagctt attttgctaa gaactttcga
    26281 aaggcacgtt tggcttatgt taagggaaat ccgcaatctc agcatttttg ggaaaagcag
    26341 ggctttaaat caattggatg cgaggttaag caagaactct atacggttgt tatcgctgaa
    26401 cagagcctag aagattagaa atggcatcaa gtaagaacta tttggaattt gttttggaac
    26461 aattatcagg attagatgat gtgacttacc gttccatgat gggggagtat attctttact
    26521 tccgcggcaa gattattggc ggcatttatg acgatcgctt tttagttaaa cccgtgcaag
    26581 cagtcttaga taagattgac caatcttctt ttgagtttcc atacaaaggt gccaaagaaa
    26641 tgatttgagt ggaagaactt gataataaga tgtttctata agacctgatt ttagctatgt
    26701 ataaccaact gccaacgccc aaacctaaaa agaaaaagca agtgtgaacg aagtaaaaaa
    26761 gaagtctgct aaggccctgt ctttgcacgg gtaaaatttt atatataaaa agaagctggg
    26821 actaaagagc tcagcttcct ttggtttata taattgtcat tacaagacga agtggttggg
    26881 cgaaactctg ttgactttat tcaatttaga gtttcttatg cacgattgag tctggaacga
    26941 aagtctccag ttgcaaagta tacagtacaa taaaccaacg atgtaatagc tgatgacaca
    27001 aagcacagtg ggtaggactt gcgaagtcac ccttttcttt tcaaaattta tactaaatca
    27061 ttgatatcag tgtagtcacg attaagtcct tgagcaactg gtaggctagt caagtaacct
    27121 tgataagtgg tcacaccttg acgcaagcct tcatcttcag agattgcttg tgcgaatcct
    27181 ttgccagcca aagcttcgat ataaggaaga gtgacattgg ttagggcgat ggttgaagtg
    27241 tgggcaaccg caccagggat attggcaacg gcatagtgga gaacaccgtg tttttcatag
    27301 acgggttcat cgtgcgttgt cacacggtca gctgtttcga taaggccacc ttggtcaaca
    27361 gcaacgtcaa cgatacagag cctggacgca tttgtttgac catctcatct gtcaccaatt
    27421 ccggtgcttt tgcaccaggg atgagaatgg ctccaatcac cacatcagca tctctcacac
    27481 ttgcttcaat gttgaatgaa ttagatataa gagtttgaat ttgacttcca aagacttctt
    27541 ctagaactga gagacgcttg gcactaatat ctaaaatagt cacttgagca ccaagaccaa
    27601 gggcgatgcg ggcagcatgt gtaccgacga caccatcacc gatgatagtt acttttcctt
    27661 ttggaacacc tggtacacca ccaggtagaa caccagagcc accagcttgc ttagtaagga
    27721 agtgagctcc gatttaaaca gccatacgac ctgcaacctc actcatagga acgaggagcg
    27781 gtagttgtcc ttgattgtca cgaacagttt cataggcaat tcctgttgtt tttgctgcta
    27841 acatagcatc tgctaattct ggagcagcgg ccatgtgcaa gtaggtgaag agaagaagat
    27901 cgtcgcgcaa gtaaccgtat tcagaactta aaggttcttt tactttcaca accaactctg
    27961 ctacccaagc ttcaccagca gtagcgacaa tctcagctcc ttgcttttga tagtcagcat
    28021 cagtaaagcc agaaccgaga ccagcatttg tttcgataag gacacgatga ccacgactaa
    28081 ctaagctatg aacacctgca ggtgtgaggg cgacacggtt ttcgttattt ttaatttctt
    28141 ttgggattcc gattaacatt gagataacct acctttcaat tgacggtctt gttttggttg
    28201 tcacattcca gttcataaat caaaaatgtg acggtttcat tgtatatgaa accgcttcaa
    28261 aaatcaagaa aaacttgtca tcccaatttt tttatgctag actagtgaaa atcaagctct
    28321 aatggaggga aaagtatgga atcaattttt gtaaaacttg cccagtatcc gtctatagaa
    28381 acggagcgtt tattgcttag acctgtaact ttggatgatg cggaagcaat gtttgactat
    28441 gcctcggaca agggtaatac acgttacact tttccaacca atcaaagctt ggaagaaacc
    28501 aagaataaca ttgctcagtt ctacttggct aatcccttgg gacgttgggg aatagaacta
    28561 aaaagcaatg gtcagtttat tggaaccatt gacttgcaca agtaaggcta atcccgcgtc
    28621 aggaaaggtc atggagaaat caggcatgcg tttttcccat gcagaaccat atgcttgtat
    28681 ggaccagcat gaaaaaggcc gaatcgtgac aagagttcat tatgtcttga ccaaggaaga
    28741 ctattttgca aataaataag cagttgaaaa gaaatttttc gactgttttt tcttcctctt
    28801 acgaataatc taagagagga gaaaatatgg aagcaattat cgagaaaatc aaagagtata
    28861 aaatcatcgt catctgtact ggtctgggct tgcttgtagg aggatttttc ctgctaaagc
    28921 cagctccaca aacacctgtc aaagagacga atttgcaggc tgaagttgca gctgtttcca
    28981 aggactcatc gaccggaaag gaagtgaaca aggaagagaa ggaagaacca gttgaacaag
    29041 atctaatcac agtagatgtc aaaggtgctg tcaaatcgcc agggatttat gacttgcctg
    29101 taggtagtcg agtcaatgat gctgttcaga aggctggtgg cttgacagag caagcagaca
    29161 gcaagtcgct caatctagct cagaaagtta gtgatgaggc tctggtttac gttcctacta
    29221 agggagaaga agcagttagt caacagactg gttcggggac agcttcttca acaagcaagg
    29281 aaaagaaggt caatctcaac aaggccagtc tggaagaact caagcaggtc aagggactgg
    29341 gaggaaaacg agctcaggac attattgacc atcgtgaggc aaatggcaag ttcaagtcag
    29401 tagacgagct caataaggtc tctggcattg gtgccaagac tatagaaaag ttaaaagact
    29461 atgttacagt ggattaagaa tttctctatt cccctaattt acctgagttt tctgttactt
    29521 tggctttact acgccatttt ttcaacatcc tatcttgctt tgttgggatt tgtttttctg
    29581 ctagtctgtc tctttttcca atttccttgg aaatctgcta gcaaagttct agtgatttgt
    29641 ggaatctttg gattttggtt tgtttttcaa aattggcaac agagtcaagc gagtcaaaat
    29701 ctggcggatt ctgttgaagg ggtacggatt ttgcctgata ctattaaggt taatggtgat
    29761 agtctatcct ttcgtggcaa gtctaacggt cgtgctttcc aagtctatta taaactccag
    29821 tccgaggagg agaaagaagc ctttcaagct ttaaccgacc tgcatgagat aggactagaa
    29881 gggaagcttt cggagccaga agggcagaga aattttggtg gctttaatta ccaagcctat
    29941 ctgaagactc agggaattta ccagactctc aatatcaaaa caatccagtc acttcaaaag
    30001 attggcagtt gggatatagg agaaaacttg tccagtttac gtcgaaaggc tgtggtttgg
    30061 attaagacgc actttccagg ccctatgcgc aattacatga caggactctt gctgggacat
    30121 ctggacaccg actttgagga gatgaatgag ctttattcca gtctaggaat tatccacctc
    30181 tttgccctat ctggcatgca ggtaggtttt ttcatgaatg gatttaagaa acttctcttg
    30241 cgattgggct tgacccaaga aaagttgaaa tggctgactt atcccttttc ccttatctat
    30301 gcgggactaa ctggattttc agcatcggtt attcgcagtc tcttgcaaaa gctactggct
    30361 caacatgggg ttaagggctt ggataatttt gccttgacgg tgcttgtcct ctttattgtc
    30421 atgccaaact ttttcttgat agcaggagga gtcttgtcct gcgcttatgc ttttatcctg
    30481 accatgacca gcaaagaagg ggaggggctc aaggctgttg ctagtgaaag tctagtcatc
    30541 tccttgggca tattgcccat tctatccttc tattttgcgg aatttcaacc ttggtctatc
    30601 cttttgacct ttgtcttttc ctttctattt gacttgacct tcttaccgct cttgtctatt
    30661 ttatttgtcc tttcctttct ctatccagtc attcagctga actttatctt tgaatggtta
    30721 gagggcatta ttcgcttggt ctcgcaggtg gcaaggagac cgcttgtctt tggtcaaccc
    30781 aacgcatggc ttttaatctt attgttaatt tccttggctt tggtctatga tttgaggaaa
    30841 aacattaaag gattaacagt attgagttta ttgattacag gtctcttttt ccttaccaag
    30901 tatccactgg aaaatgaaat caccatgctg gatgtggggc aaggagaaag tattttccta
    30961 cgggatgtaa ctgggaaaac cattctcata gatgtaggtg gtaaggcaga atcttataag
    31021 aaaatcgaaa aatggcaaga aaagatgacg accagcaatg cccagcgaac cttgattccc
    31081 tatctcaaaa gtcgaggagt agctaagatt gaccagctaa ttttgactaa cacggacaag
    31141 gagaatgttg gagatttgtc agaggtgacc aaggctttcc atgtagggga gattctagta
    31201 tcaaaagaca gtctgaaaca gaaggaattt gtggcagaac tacaggcgac tcaaacaaag
    31261 gtgcgtagta tgacagtagg ggagaacttg cccatttttg gaagtcagtt agaagttcta
    31321 tctccaagga aaatgggaga tggaggacac gatgataccc tagttctgta tgggaaattc
    31381 ttggataagc aatttctctt cacgggaaat ttggaggaga aaggagagaa ggacttgctg
    31441 aagcactatc cagacttgaa agtaaatgtt ttgaaagcta gccaacatgg caataaaaaa
    31501 tcatcaagtc cagcctttct agaaaaactc aaaccagagc ttactcttat ctcagttgga
    31561 aagagcaatc gaatgaaact cccccatcag gaaacattga cacgactgga aggtatcaat
    31621 agcaaagttt atcgaactga ccagcaagga gctatacgtt ttaaggggtt ggatagttgg
    31681 aaaatcgaaa gtgttcgata ggaaggataa atgttgtaga ttagtgaaat aaactaaaaa
    31741 tttgttgcat aataatgata aaaatggtat aatgaaaacg tattcaatat tgaggatgta
    31801 aaatcattaa aaattagcaa aaatcgttta attagttagt ttataatcta ttggtcttct
    31861 tcagtccagt gtatctgctg tgacagtcac taaaagttac aagtatgatt ggaatacggt
    31921 ttgggaatat agtaccaact atcacgacca tcagtatgct tggattccgt catggtctcg
    31981 ttatgacagc tattctgagt ataaagttgg cggaggctgg aactacggtc gttatgaggt
    32041 cataaactat tacagcggag gctattaatc cttaaagagt gagaaaagga gggctggata
    32101 tgttaaatat tactcatgtt accttaaaaa cgcgacaagt catcttgcaa gatgtggatt
    32161 tcacctttaa aaagggtagg gtttatggtc ttcttgctat caatggctct ggaaagacga
    32221 ccctgttccg tgccattagc aatttaattc ccataagtag tggaaatatc tcagcccctc
    32281 cttctttatt ttattatgag agtattgaat ggctggatgg aaacttaagt gggatggact
    32341 accttcgtct tatcaaaaac atctggaagt caggtctgaa cttgagggat gaaatcgcct
    32401 attgggaaat gtctgactat atcagtcttc ccattcgcaa gtattcctta ggcatgaagc
    32461 aacgcttggt gattgccatg tatttcctca gtcaggccaa atgctggctc atggatgaga
    32521 ttacaaatgg cttagatgag tattatcgac agaagttttt tgataggtta gcacaaatcg
    32581 atagacaaga acagctggtt cttttaagtt cccactataa ggaagagttg gttgatatct
    32641 gcgatagagt agtaaccatt catcaggggc agatagaaga ggtttagttt atgaaagatg
    32701 ttagtctatt tttattgaaa aaagttttca aaagccgctt aaactggatt atcttagctt
    32761 tatttgtatc tgtactcggt gttacttttt attttaatag tcagactgca aactcagtca
    32821 gcttggagag agagttggaa actcgtcttg tagaccgtga gagagtcatc aatgaatatg
    32881 aagagaaact ctcccaaatg tctgatacca gctcggagga ataccagttt gctaaaaata
    32941 atttagacgt gcaaaaaaat cttttgacgc gaaagacaga aattctaact ttactaaaag
    33001 aagggcgctg gaaagaggcc tactatctgc agtggcaaga tgaagagaaa gattatgaat
    33061 ttgtatcaaa tgacccgact gctagctctg aattaaaaat gggggttgac cgcgaacgga
    33121 agatttatca agccctgtat cccttgaaca taaaagcaca tactttggag tttccgaccc
    33181 acgggattga tcagattgtc tggattttag aggttatcat cccaagcttg tttgtggttg
    33241 cgattatttt tatgctaaca caactatttg cagaaagata tcaaaatcat ctggacacag
    33301 ctcacttata tcctgtttca aaagtgacat ttgcaatatc ctctcttgga gttggagtgg
    33361 gatatgtaac tgtgctgttt atcggaatct gtggcttttc ttttctagtg ggaagtctga
    33421 taagtggttt tggacagtta gattatccct acccaattta tagcttagtg aatcaagaag
    33481 taactattgg gaaaatacaa gatgtattat ttcctggctt gctcttagct ttcttagcct
    33541 ttatcgtcat tgtggaagtt gtgtacttga ttgcttactt tttcaagcaa aaaatgcctg
    33601 tcctctttct ttcactcatt gggattgttg gcttattgtt tggcatccaa acaataagcc
    33661 tcttcaaagg attgcacatc tgattccctt tacttacttg cgttcagtgg agattttatc
    33721 tggaagatta tctaagcaga ttgataatgt cgatctaaat tggagcatgg ggatggtctt
    33781 acttccttgc ctgattatcc ttttgttagt ggggattcta tttatcgaaa gatggggaag
    33841 ttcacgtaaa aaggaagttt ttaaagttta gttttcctat agggaagcta aagaaaaact
    33901 aacataggga gagaatcaac ttggttctct ctttttgatt cgaaaaccaa accaaaatac
    33961 aaacacaaac ttttcaaaaa ataacttttt atcttgacaa gagctagaaa acttggtatc
    34021 atataaaagt tgagaaaagc agaagtgaga gcttctcgcc ttgtgacatt aagttgcctg
    34081 gccctacgga tgaaaagttt cgaagaaacg ctatcataac gtgcgggctt gtatatttac
    34141 gagtccgcta ttgtttttct ctaataaaac aaaagaggtg aaaaccatag caaagcaaga
    34201 cttattcatc aatgatgaga ttcgtgtacg tgaagttcgc ttgattggtc ttgagggaga
    34261 acagctaggc atcaagccac tcagtgaagc gcaagctttg gctgataacg ctaatgttga
    34321 cctagtattg attcaacccc aagccaaacc gcctgttgca aaaattatgg actacggtaa
    34381 gttcaaattt gagtaccaga agaagcaaaa agaacaacgt aaaaaacaaa gcgttgttac
    34441 tgtgaaagaa gttcgtctaa gtccaacaat tgacaagggt gactttgata caaaacttcg
    34501 taatgcacgt aagttccttg aaaaaggaaa taaagttaag gtatctattc gctttaaggg
    34561 tcgtatgatt acccataaag agattggtgc aaaagtttta gccgagtttg ctgaagcaac
    34621 tcaagatatt gccatcatcg aacaacgtgc taaaatggat ggacgtcaaa tgttcatgca
    34681 attggcgcca gcgactgaca aaaaataatt gtcagaaagt taaataaagg agaaaaaatc
    34741 atgccaaaac aaaaaacaca ccgcgcatca gctaaacgtt tcaaacgtac aggttctggt
    34801 ggacttaaac gtttccgtgc ttacacttct caccgtttcc acggaaaaac taagaaacaa
    34861 cgtcgtcatc ttcgtaaagc atctatggtg cattcaggag attacaaacg tatcaaagca
    34921 atgcttactc gcttgaaata atagcttgac tgtaagtaaa caattctagg aaatatttgg
    34981 aggaaataaa acatggcacg tgttaaaggt ggcgttgtat cacgcaaacg tcgtaaacgt
    35041 attcttaaat tagcaaaagg ttactatgga gctaaacaca tcttgttccg tactgcaaaa
    35101 gaacaagtaa tgaactctta ctactatgca taccgtgacc gtcgtcagaa aaaacgtgac
    35161 ttccgcaaat tgtggattac tcgtatcaat gcggcagctc gtatgaacgg actttcatac
    35221 tcacaattga tgcatggttt gaaattggct gagatcgaag ttaaccgtaa aatgcttgct
    35281 gacttggctg ttaacgatgc agtagctttc acagctcttg cagatgcagc taaagcaaaa
    35341 cttggtaaat aacaactgat gagactggaa caggattgtc cagtcttttt aaaaataaag
    35401 gagaaagata tggcttcaaa aatgctacac acttgcttac gagtagaaaa tcttgaaaaa
    35461 tcaatcgcat tttatcaaga tgcttttggt tttaaagaat tgcgtcgcag agattttcca
    35521 gaccatgcct tcacgattgt ctatctaggt cttgagggtg atgattatga gttggagttg
    35581 acttataact acgatcacgg tccgtatgtg gttggtgatg ggtttgccca tatcgccctc
    35641 agtacacctg atcttgaggc acttcatcaa gaacacagtg caaaaggcta tgaagtgact
    35701 gagccaaatg gtctaccagg aactacacca aactattact ttgttaaaga ccctgatgga
    35761 tataaggtcg aagtcattcg tgaaaaataa tttcgtgcaa gttaagtaga atattcgttt
    35821 tctacttgac tttttttagc tgaaagagta tactaataaa aattcaacct ttaaggggag
    35881 tccagagaga ctcacaaggt gtcagataaa agaatagtgc aattttctag aggagacctt
    35941 ttgagtgtgc tctcttgtgt tgtacgattt taactgaggc cttgcactag caaggtcttt
    36001 tctttatctg gtccccttaa aatttaagga ggaaaagtta tgaatctcac atgtaagaag
    36061 cgtttgggtg tcattcggtt ggaaaccatg aaggtggttg cacaagagga aatcgcgcca
    36121 gcaatctttg aattagtcct agaaggagaa atggttgaag ccatgcgagc aggccaattt
    36181 cttcatctgc gtgtaccaga cgatgcccat ctcttacgtc gtcctatttc aatttcgtct
    36241 attgacaagg caaacaagca gtgtcacctc atttatcgga ttgagggagc tgggactgca
    36301 attttttcaa ccttaagtca gggagacact cttgatgtga tggggcctca gggaaatggt
    36361 tttgacttgt ctgaccttga tgagcagaat caggttctcc ttgttggtgg tgggattggt
    36421 gttccaccct tgcttgaggt ggccaaggaa ttgcatgaac gtggagtgaa agtagtgaca
    36481 gtcctcggtt ttgctaataa ggatgctgtt attttgaaaa cggaattggc tcagtatggt
    36541 caggtctttg taacgacaga tgatggttct tatggcatca agggaaatgt ttccgttgtt
    36601 atcaatgatt tagatagtca gtttgatgct gtttactcgt gtggggctcc aggaatgatg
    36661 aagtatatca atcaaacctt tgatgatcac ccaagagcct atttatctct ggaatctcgt
    36721 atggcttgtg ggatgggagc ttgctatgcc tgtgttctaa aagtaccaga aagcgagacg
    36781 gtcagccaac gcgtctgtga agatggtcct gttttccgca caggaacagt tgtattataa
    36841 ggagaaaatt atgactacaa atcgattaca agtgtctcta cctggtttgg atttgaaaaa
    36901 tccgattatt ccagcatcag gctgttttgt ctttggacaa gagtatgcca agtactatga
    36961 tttagacctt ttaggttcta ttatgatcaa ggcgacaacc cttgaaccac gttttgggaa
    37021 tccaactcca agagtggcag agacgcctgc tggtatgctc aatgcaattg gcttgcaaaa
    37081 tcctggttta gaggttgttt tggctgaaaa gctaccttgg ctggaaagag aatatccaaa
    37141 tcttcctatt attgccaatg tagctggttt ttcaaaacaa gagtatgcag ctgtttctca
    37201 tgggatttcc aaggcaacta atgtaaaagc tatcgagctc aatatttctt gtcccaatgt
    37261 tgaccactgt aatcatggac ttttgattgg tcaagatcca gatttggctt atgatgtggt
    37321 gaaagcagct gtggaagcct cagaagtgcc agtttatgtc aaattaaccc cgagtgtgac
    37381 cgatatcgtt actgtcgcaa aagctgcaga agatgcggga gcaagtggct tgaccatgat
    37441 caatactctg gttggaatgc gctttgacct caaaaccaga aaaccaatct tggccaatgg
    37501 aacaggtgga atgtcaggtc cagcagtctt tccagtagcc ctcaaactca tccgccaagt
    37561 agcccaaaca acagacctgc ctatcattgg aatgggggga gtggattcgg ctgaagctgc
    37621 cctagaaatg tatctggctg gggcatctgc tatcggagtt ggaacagcta actttaccaa
    37681 tccttatgcc tgccctgaca tcatcgaaaa tttaccaaaa gtcatggata aatacggtat
    37741 tagcagtctg gaagaactcc gtcaggaagt aaaagagtct ctgaggtaaa ctgcaatcaa
    37801 tctgttcttg attttttatt agtttgtaat atgaatttag gagaattttg gtacaataaa
    37861 ataaataaga acagaggaag aaggttaatg aagaaagtaa gatttatttt tttagctctg
    37921 ctatttttct tagctagtcc agagggtgca atggctagtg atggtacttg gcaaggaaaa
    37981 cagtatctga aagaagatgg cagtcaagca gcgaatgagt gggtttttga tactcattat
    38041 caatcttggt tctatataaa agcagatgct aactatgctg ataatgaatg gctaaagcaa
    38101 ggtgacgact atttttacct caaatctggt ggctatatgg ccaaatcaga atgggtagaa
    38161 gacaagggag tcttttatta tcttgaccaa gatggaaaga tgaaaagaaa tgcttgggta
    38221 ggaacttcct atgttggtgc aacaggtgcc aaagtaatag aagactgggt ctatgattct
    38281 caatacgatg cttggtttta tatcaaagca gatggacagc acgcagagaa agaatggctc
    38341 caaattaaag ggaaggacta ttatttcaaa tccggtggtt atctactgac aagtcagtgg
    38401 attaatcaag cttatgtgaa tgctagtggt gccaaagtgc agcaaggttg gctttttgac
    38461 aaacaatacc aatcttggtt ttacatcaaa gaaaatggaa actatgctga taaagaatgg
    38521 attttcgaga atggtcacta ttattatcta aaatccggtg gctacatggc agccaatgaa
    38581 tggatttggg ataaggaatc ttggttttat ctcaaatttg atgggaaaat agctgaaaaa
    38641 gaatgggtct acgattctca tagtcaagcc tggtactact tcaaatccgg tggttacatg
    38701 acagccaatg aatggatttg ggataaggaa tcttggtttt acctcaaatc tgatgggaaa
    38761 atagctgaaa aagaatgggt ctacgattct catagtcaag cttggtacta cttcaaatcc
    38821 ggtggttaca tgacagccaa tgaatggatt tgggataagg aatcttggtt ttacctcaag
    38881 tctgatggca aaatggctga aaaagaatgg gtctacgatt ctcatagtca agcctggtac
    38941 tacttcaaat ctggtggcta catggcgaaa aatgagacag tagatggtta tcagcttgga
    39001 agcgatggta aatggcttgg aggaaaagct acaaatgaaa atgctgctta ctatcaagta
    39061 gtgcctgtca cagccaatgt ttatgattca gatggtgaaa agctttccta tatatcgcaa
    39121 ggtagtgtcg tatggctaga taaggataga aaaagtgatg acaagcgctt ggctattact
    39181 atttctggtt tgtcaggcta tatgaaaaca gaagatttac aagcgctaga tgctagtaag
    39241 gactttatcc cttattatga gagtgatggc caccgttttt atcactatgt ggctcagaat
    39301 gctagtatcc cagtagcttc tcatctttct gatatggaag taggcaagaa atattattcg
    39361 gcagatggcc tgcattttga tggttttaag cttgagaatc ccttcctttt caaagattta
    39421 acagaggcta caaactacag tgctgaagaa ttggataagg tatttagttt gctaaacatt
    39481 aacaatagcc ttttggagaa caagggcgct acttttaagg aagccgaaga acattaccat
    39541 atcaatgctc tttatctcct tgcccatagt gccctagaaa gtaactgggg aagaagtaaa
    39601 attgccaaag ataagaataa tttctttggc attacagcct atgatacgac cccttacctt
    39661 tctgctaaga catttgatga tgtggataag ggaattttag gtgcaaccaa gtggattaag
    39721 gaaaattata tcgatagggg aagaactttc cttggaaaca aggcttctgg tatgaatgtg
    39781 gaatatgctt cagaccctta ttggggcgaa aaaattgcta gtgtgatgat gaaaatcaat
    39841 gagaagctag gtggcaaaga ttagtactat aagtgaatat gatttgagtg aatagtaagt
    39901 taaaaatcct gatttcaagt aaaatcagga ttttttcatg gatgcaattt ttttggagtc
    39961 tggtgtgacg cggagggtct tttgtcctgt gtaagtgaca aagccgggtt ttccaccagt
    40021 tggtttattg agttttttga cttcaatcat atctacctgc accagattcg acaggcgccc
    40081 ttgagagaag taggcagcta actctgctgc gtctgtcttg actgcatcag atgggtcaag
    40141 atttcctgag atgacaacat ggcttccagg aatgtcctta gcatggaacc aaagttcctc
    40201 cttgcgggcc attttaaagg tcaattcctc attttgaaga ttgtttcgtc cgacatagat
    40261 gatggttttg ccatcgcttg ctagatattg ttctagtttt ttgcgtttct ggattttctc
    40321 ccgttgtctt ctgcggataa aacctgtttg aatcaattct tcacggattt cagcgatttc
    40381 ttccagtcca gcttggttga ggacggtttc tacactttcc agatagagaa tagtggcttt
    40441 ggtttcttca atcaaatcag tcaagtattt gacagcttct ttgagtttct gataccgttt
    40501 aaaatagcgt tgggcattct ggttgggagt cagagcctta tcaagcgcaa tcatgatagg
    40561 ttggttggta tagtagttgt ctaggataac ctggtcttgg tcgttaggca cttggtggag
    40621 gaaggttgtc agcaattctc ctttttgacg aaattcttca gcgttgtctg tcgccagtaa
    40681 ctctttttcc tgttttttga gtttgtgtcg gtttttctga agttcatttt caacacgacg
    40741 aatcagttca ctggcctgct gtttgacgcg gtcgcgctca gccttatcct tatagtaggt
    40801 gtccaacaaa tcagaaagat ttgcaaaagg ctctcccacc tgatttgcaa aaggaactgg
    40861 actgaaggaa gtctcagtca agcatggctt ggtttcttga ttgaaaaaat ttcggaaagc
    40921 ggaaagtttt tcactaacca gtatcctttc caattcattt gccgtatcgc gtcccagacc
    40981 ttgaaagagg ctttgaagat tttttgctgt tagttcttgg gtttgtagga tttcaaagag
    41041 cttttcatcc ttgatagtaa aaggattgag agattttgta cttggcggag cgatataggt
    41101 cgatcctgga agtaaggtgc ggtagctatt ttgtgaaaaa ccgacgtgtt tgataacttc
    41161 gaggatttta tgactgcttt tatcgaccag tagaatatta ctgtgttttc ccataatttc
    41221 aataatcaag gtagcctgga tatggtctcc aatctcgttt ttattggaaa ctgtaatttc
    41281 cacaatacgg tcattttcca cttgctcaat cgactcaatc agggccccct gcaaatactt
    41341 tctcaaaacc atgataaagg tagaaggttg agctggattt tcaaaagtcg tttgggtcag
    41401 ctgaatgcgt ccaaaaactg gatgggcaga aaggagcagg cgatggcttt ggcgattgct
    41461 gcggatttgc aagaccaact cttgttcaaa aggctgattg attttctgga tgcgaccatt
    41521 cactaattcg cttcgcaatt cctcaactat gtggtgtaaa aaaaatccgt caaatgacat
    41581 cgttctctcc ttgtgattgt attccatagt attatatcaa aaaggtagaa taaaatcatg
    41641 gaaatgtggt ataataaagc caagtaaaga gaaacgagaa gcacatgtat attgaaatgg
    41701 tagatgaaac tggtcaagtt tcaaaagaaa tgttgcaaca aacccaagaa attttggaat
    41761 ttgcagccaa aaaattagga aaagaagaca aggagatggc agtcactttt gtgaccaatg
    41821 agcgtagtca tgaacttaat ctggagtacc gtgacaccga ccgtccgaca gatgtcatca
    41881 gccttgagta taaaccagaa ttggaaattg cctttgacga agaggatttg cttgaaaatc
    41941 cagaattggc agagatgatg tctgagtttg atgcctatat tggggaattg ttcatctcta
    42001 tcgataaggc tcatgagcag gccgaagaat atggtcacag ctttgagcgt gagatgggct
    42061 tcttggcagt acacggcttt ttacatatta acggctatga tcactatact ccggaagaag
    42121 aagcggagat gttcggttta caagaagaaa ttttgacagc ctatggactc acaagacaat
    42181 aaacgaaaat ggaaaaatcg tgacttgata tccagtttag aatttgccat cacagggatt
    42241 tttactgcta tcaaggaaga acgaaatatg cgaaaacatg cagtgacggc tctagtggtc
    42301 atccttgcag gttttgtttt tcaggtgtca cgaatcgaat ggctctttct cctattgagt
    42361 attttcttgg tagtagcctt tgagattatc aactctgcta ttgaaaatgt ggtggatttg
    42421 gccagtcact atcacttttc catgctggct aaaaatgcca aggatatggc ggccggcgcg
    42481 gtattagtgg tttctctttt cgcagcctta acaggcgcat tgatttttct cccacgaatc
    42541 tgggatttat tattttaaac agtaagagga aattatgact tttaaatcag gctttgtagc
    42601 cattttagga cgtcccaatg ttgggaagtc aaccttttta aatcacgtta tggggcaaaa
    42661 gattgccatc atgagtgaca aggcgcagac aacgcgcaat aaaatcatgg gaatttacac
    42721 gactgataag gagcaaattg tctttatcga cacaccaggg attcacaaac ctaaaacagc
    42781 tctcggagat ttcatggttg agtctgccta cagtaccctt cgcgaagtgg acaccgttct
    42841 tttcatggtg cctgctgatg aagcgcgtgg taagggggac gatatgatta tcgagcgtct
    42901 caaggctgcc aaggttcctg tgattttggt ggtgaataaa atcgataagg tccatccaga
    42961 ccagctcttg tctcagattg atgacttccg taatcaaatg gactttaagg aaattgttcc
    43021 aatctcagcc cttcagggaa ataacgtgtc tcgtctagtg gatattttga gtgaaaatct
    43081 ggatgaaggt ttccaatatt tcccgtctga tcaaatcaca gaccatccag aacgtttctt
    43141 ggtttcagaa atggttcgcg agaaagtctt gcatctaact cgtgaagaga ttccgcattc
    43201 tgtagcagta gttgttgact ctatgaaacg agacgaagag acagacaagg ttcacatccg
    43261 tgcaaccatc atggtcgagc gcgatagcca aaaagggatt atcatcggta aaggtggcgc
    43321 tatgcttaag aaaatcggta gcatggcccg tcgtgatatc gaactcatgc taggagacaa
    43381 ggtcttccta gaaacctggg tcaaggtcaa gaaaaactgg cgcgataaaa agctagattt
    43441 ggctgacttt ggctataatg aaagagaata ctaagtagag gtaggctcat gcctgcttct
    43501 tgtttttaca gaaggaggac ttatgcctga attacctgag gttgaaaccg tttgtcgtgg
    43561 cttagaaaaa ttgattatag gaaagaagat ttcgagtata gaaattcgct accccaagat
    43621 gattaagacg gatttggaag agtttcaaag ggaattgcct agtcagatta tcgagtcaat
    43681 gggacgtcgt ggaaaatatt tgctttttta tctgacagac aaggtcttga tttcccattt
    43741 gcggatggag ggcaagtatt tttactatcc agaccaagga cctgaacgca agcatgccca
    43801 tgttttcttt cattttgaag atggtggcac gcttgtttat gaggatgttc gcaagtttgg
    43861 aaccatggaa ctcttggtgc ctgacctttt agacgcctac tttatttcta aaaaattagg
    43921 tcctgaacca agcgaacaag actttgattt acaggtcttt caagctgccc ttgccaagtc
    43981 caaaaagcct atcaaatccc atctcctaga ccagaccttg gtagctggac ttggcaatat
    44041 ctatgtggat gaggttctct ggcgagctca ggttcatcca gctagacctt cccagacttt
    44101 gacagcagaa gaagcgactg ccattcatga ccagaccatt gctgttttgg gccaggctgt
    44161 tgaaaaaggt ggctccacca ttcggactta taccaatgcc tttggggaag atggaagcat
    44221 gcaggacttt catcaggtct atgataagac tggtcaagaa tgtgtacgct gtggtaccat
    44281 cattgagaaa attcaactag gcggacgagg cacccacttt tgtccaaact gtcaaaggag
    44341 ggactgatga gaaaaatcat cggaatcact gggggaattg cctctggtaa gtcaactgtg
    44401 acaaattttc taagacagca aggctttcaa gtagtggatg ccgacgcagt cgtccaccaa
    44461 ctacagaaat ctggtggtcg tctgtttgag gctctagtac agcactttgg gcaagaaatc
    44521 attcttgaaa acggagaact caatcgccct ctcctagcta gtctcatctt ttcaaatcct
    44581 gaagagcaaa aatggtctaa gcaaattcaa ggggagatta tccgtgagga actggctact
    44641 ttgagagaac agttggctca gacagaagag attttcttca tggatattcc cctacttttt
    44701 gagcaggact acagcgattg gtttgctgag acttggttgg tctatgtgga ccgagatgcc
    44761 caagtagaac gcttaatgaa aagggaccag ttgtccaaag atgaagctga gtctcgtctg
    44821 gcagcccagt ggcctttaga aaaaaagaaa gatttggcca gccaggttct tgataataat
    44881 ggcaatcaga accagcttct taatcaagtg catatccttc ttgagggagg taggcaagat
    44941 gacagagatt aactggaagg ataatctgcg tattgcctgg tttggtaatt ttctgacagg
    45001 agccagtatt tctttggttg taccttttat gcccatcttc gtggaaaatc taggtgtagg
    45061 gagtcagcaa gtcgcttttt atgcaggctt agcaatttct gtctctgcta tttccgcggc
    45121 gctcttttct cctatttggg gtattcttgc tgacaaatac ggccgaaaac ccatgatgat
    45181 tcgggcaggt cttgctatga ctatcactat gggaggcttg gcctttgtcc caaatatcta
    45241 ttggttaatc tttcttcgtt tactaaacgg tgtatttgca ggttttgttc ctaatgcaac
    45301 ggcactgata gccagtcagg ttccaaagga gaaatcaggc tctgccttag gtactttgtc
    45361 tacaggcgta gttgcaggta ctctaactgg tccctttatt ggtggcttta tcgcagaatt
    45421 atttggcatt cgtacagttt tcttactggt tggtagtttt ctatttttag ctgctatttt
    45481 gactatttgc tttatcaagg aagattttca accagtagcc aaggaaaagg ctattccaac
    45541 aaaggaatta tttacctcgg ttaaatatcc ctatcttttg ctcaatctct ttttaaccag
    45601 ttttgtcata caattttcag ctcaatcgat cggccctatt ttggctcttt atgtacgcga
    45661 cttagggcag acagagaatc ttctttttgt ctctggtttg attgtgtcca gtatgggctt
    45721 ttccagcatg atgagtgcag gagtcatggg caagctaggt gacaaggtgg gcaatcatcg
    45781 tctcttggtt gtcgcccagt tttatttagt catcatctat ctcctctgtg ccaatgcctc
    45841 tagcccgctt caactaggac tttatcgatt cctctttgga ttgggaaccg gtgccttgat
    45901 tcccggggtt aatgccctac tcagcaaaat gactcccaaa gccggcattt cgagggtctt
    45961 tgccttcaat caggtattct tttatctggg aggtgttgtt ggtcccatgg caggttctgc
    46021 agtagcaggt caatttggct accatgctgt cttttatgcg acgagccttt gtgttgcctt
    46081 tagttgtctc tttaacctga ttcaatttcg aacattatta aaagtaaagg aaatctagtg
    46141 cgagtaaaaa ttaatctcaa atgctcctct tgtgacagta tcaattacct aaccagtaaa
    46201 aattcaaaaa cccatccaga caagattgag gttttaaagt attgtcccaa ggaaagaaaa
    46261 gtaaccctac atcttgaatc taagtagatt ttatggtaaa ataataggga ttttaaggag
    46321 tttgatatgt ataacctatt attaaccatt ttattagtat tatctgttgt gattgtgatt
    46381 gcaattttca tgcaaccaac caaaaaccaa tccagcaatg tatttgatgc cagttcaggt
    46441 gatttgtttg aacgcagtaa agctcgcggt tttgaagctg taatgcagcg tttgacaggg
    46501 attttagtct ttttctggct agccattgcc ttagcattga cggtattatc aagtagataa
    46561 gaaaataatg ggcaggacta ggtctttgcc tctttttatt tttaaaggat gtttgagaag
    46621 gttttacagt aaaagaaaat taaaaaatct agaaagaaaa tatgaaagat agaataaaag
    46681 aatatttaca agacaaggga aaggtgactg ttaatgattt ggctcaggct ttgggaaaag
    46741 acagttccaa ggattttcgt gagttgatta aaaccttgtc cttaatggaa agaaagcacc
    46801 agattcgctt tgaagaagat ggcagtctga ccttggaagc caagaaaaaa catgagatta
    46861 ccctcaaggg gatttttcat gcccataaaa atggttttgg ttttgtcagc ctagaagggg
    46921 aagaggacga cctttttgta gggaaaaatg atgtcaacta tgctattgat ggtgataccg
    46981 tcgaggtagt gattaagaaa gtcgctgacc gcaataaggg aacagcagca gaagccaaaa
    47041 ttattgatat cctagaacac agtttgacaa cagttgtcgg gcaaatcgtt ctggatcagg
    47101 aaaagcctaa gtatgctggc tatattcgtt caaaaaatca gaaaatcagt caaccgattt
    47161 atgttaagaa accagcccta aaattagaag gaacagaagt tctcaaagtc tttatcgata
    47221 aatacccaag caagaaacat gatttctttg tcgctagtgt actcgatgta gtgggacact
    47281 caacggatgt cggaattgat gttcttgagg tcttggaatc aatggacatt gtatccgagt
    47341 ttccagaagc tgttgttaag gaagcagaaa gtgtgcctga tgctccgtct caaaaggata
    47401 tggaaggtcg tctggatcta agagatgaaa ttacctttac cattgacggt gcggatgcca
    47461 aggacttgga cgatgcagtg catatcaagg ctctgaaaaa tggcaatctg gagcttgggg
    47521 ttcacattgc agatgtttct tattatgtga ccgaggggtc tgcccttgac aaggaagccc
    47581 ttaaccgtgc gacttctgtt tacgtgacag accgagtggt gccaatgctt ccagaacgac
    47641 tatcaaatgg catctgctct ctcaatcccc aagttgaccg cctgacccag tctgctatta
    47701 tggagattga taaacatggt cgtgtggtca actataccat tatacaaaca gttatcaaga
    47761 ccagttttcg tatgacctat agcgatgtca atgatatcct agctgtcgat gaagaaaaga
    47821 gaaaagaata tcataaaatt gtatcaagta tcgaactcat ggccaagctt catgaaactt
    47881 tagaaaacat gcgtgtgaaa cgtggagctc tcaattttga taccaatgaa gcgaagattt
    47941 tagtggataa acaaggtaag cctgttgata tcgttcttcg gcagcgtggc attgccgagc
    48001 ggatgattga gtcttttatg ttgatggcta atgaaacagt tgccgaacat ttcagcaagt
    48061 tggatttgcc ttttatctat cgaattcacg aggagcctaa ggctgaaaag gttcagaagt
    48121 ttattgatta tgcttcgagt tttggcttgc gtatttatgg gactgccagt gagattagtc
    48181 aggaggcact tcaagacatc atgcgtgctg ttgagggaga accttatgca gatgtattgt
    48241 ccatgatgct tcttcgctct atgcagcagg ctcgttattc ggagcacaat cacggccact
    48301 atggactagc tgctgactat tatactcact ttaccagtcc aattcgtcgt tatccagacc
    48361 ttcttgttca ccgtatgatt cgggattacg gccgttctaa ggaaatagca gagcattttg
    48421 aacaagtgat tccagagatt gcgacccagt cttccaaccg tgaacgtcgt gccatagaag
    48481 ctgagcgtga agtcgaagcc atgaaaaagg ctgagtatat ggaagaatac gtgggtgaag
    48541 agtatgatgc agttgtatca agtattgtca aattcggtct ctttgtcgaa ttgccaaaca
    48601 cagttgaagg cttgattcac atcactaatc tacctgaatt ttatcatttc aatgagcgtg
    48661 atttgactct tcgtggagaa aaatcaggta tcactttccg agtgggtcag cagatccgta
    48721 tccgtgttga aagagcggat aaaatgactg gagagattga tttttcattc gtacctagtg
    48781 agtttgatgt gattgaaaaa ggcttgaaac agtctagtca tagtggcaga gggcgtggtt
    48841 caaatcgtcg ttcggataag aaggaagaca agagaaaatc aggacgctca aatgataagc
    48901 gtaagcattc acaaaaagac aagaagaaaa aaggaaagaa acctttttac aaggaagtag
    48961 ctaagaaagg agccaagcat ggcaaagggc gagggaaagg tcgtcgcaca aaataaaaag
    49021 gcacgccacg actatacaat cgtagatacg ctagaggcag ggatggtcct gactggaact
    49081 gaaatcaaga gtgtacgagc tgctcgaatt aatctcaagg atggctttgc tcaagtgaaa
    49141 aatggagaag tttggctgag caatgttcat atcgcgcctt acgaagaggg caatatctgg
    49201 aaccaggaac cagaacgtcg tcgtaaactc ctgctccata aaaagcaaat tcaaaaattg
    49261 gaacaagaga ccaaagggac aggaatgacc ttagttcccc ttaaggtcta tataaaagat
    49321 ggctacgcta agcttctttt aggacttgcc aaagggaagc atgactatga caaacgggag
    49381 tctatcaaac gtcgtgagca aaatcgagat atcgcgcgtg tgatgaaagc tgttaatcag
    49441 cgataaaaag aggaattgaa aatggaaaaa ttagttgcct ataaacgcat gcctttgtgg
    49501 aataaacaaa caatgcctga agctgttcag caaaagcaca atacaaaagt tgggacttgg
    49561 gggaaaatta ctgtcttgaa gggagctctc aagtttattg aattgacaga agaaggggaa
    49621 gttctagctg aacacctctt tgaagcaggg gcagacaatc caatggccca acctcaagcc
    49681 tggcaccgag tggaagctgc cacagatgat gtggaatggt acttggaatt ttattgtaaa
    49741 cctgaggatt attttgctaa aaaatacaat accaatcctg ttcattcaga ggtcctagag
    49801 gccatgcaga cagtgaaaca agggaaagct ttggatttgg gttgtggtca gggacgtaat
    49861 tctctttttc tagcccagca agattttgat gtgacggctg tagatcaaaa tggactagct
    49921 cttgaaatct tgcaaagcat tgtggagcag gaagatttgg acatgcctgt tggcctttac
    49981 gatatcaatt cagctagcat tgaacaagaa tatgatttta tcgtttcaac agttgttctc
    50041 atgtttctac aagcggaccg cattccagct attattcaaa atatgcagga gaaaaccagt
    50101 gttggtggtt acaaccttat cgtttgtgcc atggacacgg aggattatcc ttgctcggtt
    50161 aacttcccat tcacctttaa agaaggagaa ctggcagact attacaagga ttgggaattg
    50221 gttaagtaca atgaaaatcc aggccatttg catcgtcgcg atgagaatgg caatcgtatt
    50281 caactacgct ttgcgacctt actagctaag aaaatcaagt aaacacacat gaagattagg
    50341 aattttcctg atcttttttc ttttttacga atgatataga aaaggaggga attcatgttt
    50401 gttgcgagag atgctagggg agaattggta aatgtgttag aggataaact tgagaagcaa
    50461 gcatacacct gcccagcttg tggaggccag atccatttgc gtcaaggacc aagtgtacgg
    50521 acgcattttg cccataaatc cttaaaagac tgtgattttt tctttgaaaa tgaaagtcca
    50581 gaacacatag ccaataagga atccctctat cactggttga aaaaagagac aaaggttcaa
    50641 ttagagtacc cgctttcaga acttaaacag attgcggatg tatttgtaaa tggcaatcta
    50701 gctctagaag ttcagtgtag tcccttgcct cagaaagtcc ttaaagagcg aagtgagggc
    50761 tatcgtagtc agggttacca agtactgtgg ttgctgggta aaaaactgtg gctcaaggag
    50821 cgtttgactt gtctacagca aggttttctt tatttcagtc aaaacatggg cttttatgtt
    50881 tgggaattag acaaggaaaa acaagtttta agactcaaat acctgattta ccaggatctc
    50941 cgcggtaaac tccattatca aatcaaggaa ttttcctatg gtcaaggtag tttattggaa
    51001 atattgcgtc ttccctataa gagacaaaaa atatctcatt ttacagtttc tgaggacaag
    51061 gacatctgtc gctatatccg gcaacaactt tattatcaaa atctcttttg gatgaaagaa
    51121 caagcagaag cctatcaaaa gggagaaaat atcctgactt atggactgaa agaatggtat
    51181 ccacaaattc gaccaatagt gggcaaattt ttccagatta aacaagactt gactagctat
    51241 tatcagcact tttataccta ttaccaaaaa aatcctcaaa atgattggca aaagctttat
    51301 ccaccagcct tttatcagca atatttcttg aaaaatatgg tagaatagaa aggatggagg
    51361 aatctaatgg tattacaaag aaatgaaata aatgaaaaag atacatggga tctatcaacg
    51421 atctacccaa ctgaccaggc ttgggaagaa gccttaaaag atttaacaga acaattggag
    51481 acagtagccc agtatgaagg ccatctcttg gatagtgcgg ataacctact agaaatcact
    51541 gaattttctc ttgaaatgga acgccagatg gagaagcttt acgtttatgc tcatatgaag
    51601 aatgaccagg atacacgtga agctaagtat caagagtact atgccaaggc catgacactc
    51661 tacagccagt tagaccaagc cttttcattc tatgagcctg aatttatgga gattagcgaa
    51721 aagcagtatg ctgacttttt agaagctcaa ccaaagctgc aggtttatca acactatttt
    51781 gacaagctct tgcaaggcaa ggatcacgtt ctctcacaac gtgaagaaga attattggct
    51841 ggagctggag aaatctttgg ttcagcaagt gaaaccttcg ctatcttgga caatgcggat
    51901 attgtgttcc cttatgtcct agacgatgat ggtaaagaag ttcagctatc tcatgggact
    51961 tacacacgtt tgatggagtc taaaaaacgt gaggttcgcc gtggtgccta tcaagctctt
    52021 tatgcgactt acgaacaatt ccaacacacc tatgccaaaa ccttgcaaac caatgttaag
    52081 gtgcaaaatt accgtgctaa agttcgtaac tacaagagtg ctcgtcatgc agccctcgca
    52141 gcgaattttg ttccagaaag tgtttatgac aatttggtag cagcagttcg caagcatttg
    52201 ccactcttac atcgctatct tgagcttcgt tcaaaaatct tggggatttc agatctcaag
    52261 atgtacgatg tttacacacc gctttcatct gttgaataca gttttaccta ccaagaagcc
    52321 ttgaaaaaag cagaagatgc tttggcagtc ttgggtgagg attacttgag ccgtgttaaa
    52381 cgtgccttca gcgagcgttg gattgatgtt tacgaaaatc aaggcaagcg ttcaggtgcc
    52441 tactctggtg gttcttacga taccaatgcc tttatgcttc tcaactggca ggacaatctg
    52501 gacaatctct ttactcttgt tcatgaaaca ggtcacagta tgcattcaag ctatactcgt
    52561 gaaactcagc cttatgttta cggagattac tctatctttt tggctgagat tgcctcaact
    52621 accaatgaaa atatcttgac ggagaaatta ttggaagaag tggaagacga cgcaacacgt
    52681 tttgctattc tcaataactt cctagatggt ttccgtggaa cagttttccg ccaaactcaa
    52741 tttgctgagt ttgaacacgc cattcaccaa gcagatcaaa atggggaggt cttgacaagc
    52801 gatttcctaa ataaactcta cgcatacttg aaccaagagt attatggttt gagtaaggaa
    52861 gacaatcctg aaatccaata cgagtgggct cgcattccac acttctacta taactactat
    52921 gtatatcaat attcaactgg ctttgcggcc gcctcagcct tggctgaaaa aattgtccat
    52981 ggtagtcaag aagaccgtga ccgctatatc gactacctca aggcaggtaa gtcggactat
    53041 ccacttaatg tcatgagaaa agctggtgtt gatatggaga aggaagacta cctcaacgat
    53101 gcctttgcag tctttgaacg ccgtttaaat gagtttgaag cccttgttga aaaattagga
    53161 ttggcataaa atggttgaat cgtatagtaa gaatgctaac cataacatgc gtcgtcctgt
    53221 cgtcaaagaa gaaattgtag acttgatgcg tcagcgtcaa aagcaagtca caggtttctt
    53281 gaaagaattg gaagactttg cccgcaagga aaatattcct attattcccc atgaaacggt
    53341 tgcttatttc cgttttctta tggaaaccat gcagcctaaa aatattctgg aaattgggac
    53401 ggctatcggt ttttcagctc tcttgatggc tgaacatgcg ccaaatgcta agattacaac
    53461 tattgatcgt aatccagaaa tgattggttt tgccaaggaa aattttgccc agtttgacag
    53521 tcgcaagcaa atcactctcc tagagggaga tgcggtggat gtcttatcta cactgacaga
    53581 gtcttatgat ttcgtcttta tggattctgc caagtctaaa tacatcgtct ttctgccaga
    53641 aatcctcaaa catttggaag ttggtggtgt ggttgtcttg gatgatattt ttcaaggtgg
    53701 tgatgttgcc aaggatatta tggaagtccg tcgtggtcag cgaaccattt atcgaggcct
    53761 tcaaaaatta tttgatgcaa ccttagacaa tccagaactc accgcaacat tagtgccttt
    53821 aggagatggt attctcatgc ttcgtaaaaa tgtagcagat gttcaactgt ctgaaagcga
    53881 atgattttca gaaaaattta agaaaaaata gtaaaataga tagagtaaca cttatctcaa
    53941 aggagtagac atgaagaaaa aattattggc aggtgccatc acactattat cagtagcaac
    54001 tttagcagct tgttcgaaag ggtcagaagg ggcagacctt atcagtatga aaggggatgt
    54061 catcacagaa catcaatttt atgagcaagt gaaaaacaac ccttcagccc aacaagtctt
    54121 gttaaatatg accatccaaa aagtttttga aaaacaatat ggctcagagc ttgatgataa
    54181 agaggttgat gatactattg ccgaagaaaa aaaacaatat ggcgaaaact accaacgtgt
    54241 cttgtcacaa gcaggtatga ctcttgaaac acgtaaagct caaattcgta caagtaaatt
    54301 agttgagttg gcagttaaga aggtagcaga agctgaattg acagatgaag cctataagaa
    54361 agcctttgat gagtacactc cagatgtaac ggctcaaatc atccgtctta ataatgaaga
    54421 taaggccaaa gaagttctcg aaaaagccaa ggcagaaggt gctgattttg ctcaattagc
    54481 caaagataat tcaactgatg aaaaaacaaa agaaaatggt ggagaaatta cctttgattc
    54541 tgcttcaaca gaagtacctg agcaagtcaa aaaagccgct ttcgctttag atgtggatgg
    54601 tgtttctgat gtgattacag caactggcac acaagcctac agtagccaat attacattgt
    54661 aaaactcact aagaaaacag aaaaatcatc taatattgat gactacaaag aaaaattaaa
    54721 aactgttatc ttgactcaaa aacaaaatga ttcaacattt gttcaaagca ttatcggaaa
    54781 agaattgcaa gcagctaata ttaaggttaa ggaccaagcc ttccaaaata tctttaccca
    54841 atatatcggt ggtggagatt caagctcaag cagtagtaca tcaaacgaat agtccaaatc
    54901 aatgagtcag ggaaaaaact cgacttcagg aaaaaatgaa gcaaacattc ccacaataaa
    54961 acgcatagta caaggtttgt actgcccccc aaaaaagtta gacaattaat ttatccgaag
    55021 gatttagttc tgtattgcac agagctaagt ccttttagtt ttatcttaat tctcttattg
    55081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
    55141 tgctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
    55201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
    55261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
    55321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
    55381 taagattaga attgtttatc ccaaatttat ttgaaagctt ctctaagctt aagctatatc
    55441 cttgttttct aagttcatag at
//
LOCUS       DBEJNA010000011        51484 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEJNA010000011 DBEJNA010000000
VERSION     DBEJNA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 51484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.11"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(617..1295)
                     /locus_tag="ACL3JB_000737"
                     /pseudo
     CDS             complement(617..1295)
                     /locus_tag="ACL3JB_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1363..3185)
                     /locus_tag="ACL3JB_000738"
                     /pseudo
     CDS             complement(1363..3185)
                     /locus_tag="ACL3JB_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(3172..3537)
                     /locus_tag="ACL3JB_000739"
     CDS             complement(3172..3537)
                     /locus_tag="ACL3JB_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGR0685516.1"
                     /translation="MENRYRTNLKKVFLSDSELGQLKHCIDQSGCQSFSEYARRTLLD
                     PGMNFITIDTTGYQDLVFELKRIGNNINQIARSVNQSQLISSEELQDLKKGIADLIRE
                     VEKEFSIQAKKLREFHGHH"
     gene            complement(3542..3898)
                     /locus_tag="ACL3JB_000740"
     CDS             complement(3542..3898)
                     /locus_tag="ACL3JB_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR0685517.1"
                     /translation="MPEQYRDIRKEVNLTANELEMIGVMMKNKGFEHFSSFARNKLLE
                     NELEMTAEKWFTFWRAQKLEQISRDVYEILILSRAEHQVTQEHVSILLTCVQELIQEI
                     GNSIPLSQDFRKKYMR"
     gene            complement(4792..6330)
                     /locus_tag="ACL3JB_000741"
     CDS             complement(4792..6330)
                     /locus_tag="ACL3JB_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGR0685518.1"
                     /translation="MSDIATQDKNVKKELLEYQGNILILANAGSGKTTFLTKKLKSDS
                     KRLNNYQKLAAITFTRNATEEIKQKLVDIPDNVVVSTIDSFLDKEIILPFLNQKYEIQ
                     TSVQFSFRIDHNFSDYSTGIKQILQDGIFGTYDFPTSKHGKNFKCEVALDILKTIDSA
                     SEYIKYKFNTLYIDEFQDCDQSMNDLFLYLKNELGIPLFIVGDDKQSIYQWRGASPKY
                     INNLWKNKNDFRKKRFIGNFRSLPRIVDFSLALTPEVTVDNIREEGSILYLEPNQDYP
                     KEDIIKYLIDNGDINLQEKNYFLIGINKDIEETATHLNDILSNKVDYVRKNPFIDCTN
                     SNFLQSMAQYYFLEDFSEYDVLNNLFPEYNDEFRKELLKKLKRLRQRPTQSLIEEIAS
                     YLDVSITNYEDKLESQILLEILSNLDNKKMFDTNLMSNNLLMTTHASKGLAADTVVIF
                     VEYLIDWRTGLKFEDHYVAITRAKSKVIIIDNRTIYTSEINRLLSNNNGNFSFEDFIE
                     RRYI"
     gene            complement(6323..8080)
                     /locus_tag="ACL3JB_000742"
     CDS             complement(6323..8080)
                     /locus_tag="ACL3JB_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0685519.1"
                     /translation="MEFKKLVIENFRNFSSIEVALSNKNVIFGMNDSGKTNLLFAIRY
                     LLDRTIRNKGFIKSDYYRHDTSRPIKIQLELDLSDRKMEGDEESLKSSHSRLLISTVA
                     GARNNSSLDTFFISLEAVYNEKELFGNPVLSWGSTLDNLVEVPQYGTRSDIDKIFQIV
                     YVNPAIELDSFFKRNRRILFSDDSKTDEDVKLEEEIENNIEKLNENISNLHLITSVQS
                     QLTEAYKSYRKENLEIKIQSEISISGYLDNLTPYINWNDDTHNYPTSGDGRKKLLSYA
                     INHLISEKQYNKKVIIYLIEEPENSLHRSVQISLSKQLFVQNIYEYFFLTTHSAEVLY
                     EMDNTQLIKITNQQDATGQSVYYTVPNEFSNLKKKLNKSLAQSIFYDRILLVEGPSEY
                     YLFSAIFEYVSPNFEADGKYLLQVDGINFKPYSELYKALGIDFWIKTDNDLKASRGDK
                     HVFSPIGLNRCIDLLDHSATPILDNYRIDFSSKDERKQNIKSKKEELYLTNHNLVLQL
                     NADGIFISEIDLENDLAQVLSDSERNEMSKLDFVNWLQSSKQYNMLEYISNHLTKEIA
                     LKIVESGYFKVLAEFLDYE"
     gene            complement(8070..8846)
                     /gene="pezT"
                     /locus_tag="ACL3JB_000743"
     CDS             complement(8070..8846)
                     /gene="pezT"
                     /locus_tag="ACL3JB_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR0685520.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKFSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVVEERHKELEGKNSYGI"
     gene            complement(8846..9322)
                     /gene="pezA"
                     /locus_tag="ACL3JB_000744"
     CDS             complement(8846..9322)
                     /gene="pezA"
                     /locus_tag="ACL3JB_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR0685521.1"
                     /translation="MIGKNIKSLRKTHDLTQDEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(9767..10192)
                     /locus_tag="ACL3JB_000745"
                     /pseudo
     CDS             complement(9767..10192)
                     /locus_tag="ACL3JB_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10169..10901)
                     /locus_tag="ACL3JB_000746"
                     /pseudo
     CDS             complement(10169..10901)
                     /locus_tag="ACL3JB_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(11063..11947)
                     /locus_tag="ACL3JB_000747"
     CDS             complement(11063..11947)
                     /locus_tag="ACL3JB_000747"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0685522.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKTFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(12059..12913)
                     /locus_tag="ACL3JB_000748"
     CDS             complement(12059..12913)
                     /locus_tag="ACL3JB_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0685523.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(12971..13729)
                     /locus_tag="ACL3JB_000749"
     CDS             complement(12971..13729)
                     /locus_tag="ACL3JB_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0685524.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFYEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYVGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(13791..13979)
                     /locus_tag="ACL3JB_000750"
     CDS             complement(13791..13979)
                     /locus_tag="ACL3JB_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0685525.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(14302..14868)
                     /locus_tag="ACL3JB_000751"
     CDS             complement(14302..14868)
                     /locus_tag="ACL3JB_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685526.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(15136..16814)
                     /locus_tag="ACL3JB_000752"
                     /pseudo
     CDS             complement(15136..16814)
                     /locus_tag="ACL3JB_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(16906..17067)
                     /locus_tag="ACL3JB_000753"
     CDS             complement(16906..17067)
                     /locus_tag="ACL3JB_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685527.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(17751..18455)
                     /locus_tag="ACL3JB_000754"
     CDS             complement(17751..18455)
                     /locus_tag="ACL3JB_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR0685528.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINKGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIDKEREGEIDKKSTPIFYGEF
                     KNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLR
                     QKGLNKKMNYDVGESL"
     gene            complement(18582..19109)
                     /locus_tag="ACL3JB_000755"
     CDS             complement(18582..19109)
                     /locus_tag="ACL3JB_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGR0685529.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(19295..19468)
                     /locus_tag="ACL3JB_000756"
     CDS             complement(19295..19468)
                     /locus_tag="ACL3JB_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685530.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(19542..21182)
                     /gene="mobQ"
                     /locus_tag="ACL3JB_000757"
                     /pseudo
     CDS             complement(19542..21182)
                     /gene="mobQ"
                     /locus_tag="ACL3JB_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(21496..21813)
                     /locus_tag="ACL3JB_000758"
     CDS             complement(21496..21813)
                     /locus_tag="ACL3JB_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGR0685531.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(21869..22294)
                     /locus_tag="ACL3JB_000759"
     CDS             complement(21869..22294)
                     /locus_tag="ACL3JB_000759"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0685532.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(22347..22531)
                     /locus_tag="ACL3JB_000760"
                     /pseudo
     CDS             complement(22347..22531)
                     /locus_tag="ACL3JB_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(22682..23476)
                     /locus_tag="ACL3JB_000761"
     CDS             complement(22682..23476)
                     /locus_tag="ACL3JB_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685533.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            complement(23476..24483)
                     /locus_tag="ACL3JB_000762"
     CDS             complement(23476..24483)
                     /locus_tag="ACL3JB_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR0685534.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(24483..25490)
                     /locus_tag="ACL3JB_000763"
     CDS             complement(24483..25490)
                     /locus_tag="ACL3JB_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0685535.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(25480..26505)
                     /locus_tag="ACL3JB_000764"
     CDS             complement(25480..26505)
                     /locus_tag="ACL3JB_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0685536.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(26898..27116)
                     /locus_tag="ACL3JB_000765"
     CDS             complement(26898..27116)
                     /locus_tag="ACL3JB_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0685537.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(27362..27640)
                     /locus_tag="ACL3JB_000766"
     CDS             complement(27362..27640)
                     /locus_tag="ACL3JB_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685538.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVFELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(27854..29476)
                     /gene="rlmD"
                     /locus_tag="ACL3JB_000767"
     CDS             complement(27854..29476)
                     /gene="rlmD"
                     /locus_tag="ACL3JB_000767"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0685539.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREH
                     YNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(29550..30524)
                     /locus_tag="ACL3JB_000768"
     CDS             complement(29550..30524)
                     /locus_tag="ACL3JB_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0685540.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(30598..31212)
                     /gene="pmp23"
                     /locus_tag="ACL3JB_000769"
     CDS             complement(30598..31212)
                     /gene="pmp23"
                     /locus_tag="ACL3JB_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0685541.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(31212..32186)
                     /locus_tag="ACL3JB_000770"
     CDS             complement(31212..32186)
                     /locus_tag="ACL3JB_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0685542.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(32194..33450)
                     /gene="glyA"
                     /locus_tag="ACL3JB_000771"
     CDS             complement(32194..33450)
                     /gene="glyA"
                     /locus_tag="ACL3JB_000771"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0685543.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAALIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(33512..33943)
                     /locus_tag="ACL3JB_000772"
     CDS             complement(33512..33943)
                     /locus_tag="ACL3JB_000772"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685544.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(33945..34544)
                     /locus_tag="ACL3JB_000773"
     CDS             complement(33945..34544)
                     /locus_tag="ACL3JB_000773"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0685545.1"
                     /translation="MDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(34531..35370)
                     /gene="prmC"
                     /locus_tag="ACL3JB_000774"
     CDS             complement(34531..35370)
                     /gene="prmC"
                     /locus_tag="ACL3JB_000774"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0685546.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPAWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(35370..36449)
                     /gene="prfA"
                     /locus_tag="ACL3JB_000775"
     CDS             complement(35370..36449)
                     /gene="prfA"
                     /locus_tag="ACL3JB_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0685547.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(36446..37036)
                     /locus_tag="ACL3JB_000776"
     CDS             complement(36446..37036)
                     /locus_tag="ACL3JB_000776"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0685548.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            37159..37341
                     /locus_tag="ACL3JB_000777"
     CDS             37159..37341
                     /locus_tag="ACL3JB_000777"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0685549.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            37477..38850
                     /gene="mnmE"
                     /locus_tag="ACL3JB_000778"
     CDS             37477..38850
                     /gene="mnmE"
                     /locus_tag="ACL3JB_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0685550.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(38897..39832)
                     /gene="dapA"
                     /locus_tag="ACL3JB_000779"
     CDS             complement(38897..39832)
                     /gene="dapA"
                     /locus_tag="ACL3JB_000779"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0685551.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(39888..40964)
                     /locus_tag="ACL3JB_000780"
     CDS             complement(39888..40964)
                     /locus_tag="ACL3JB_000780"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0685552.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(41307..41379)
                     /locus_tag="ACL3JB_000781"
     tRNA            complement(41307..41379)
                     /locus_tag="ACL3JB_000781"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(41344..41346),aa:Thr,seq:ggt)
     gene            complement(41479..41988)
                     /locus_tag="ACL3JB_000782"
     CDS             complement(41479..41988)
                     /locus_tag="ACL3JB_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0685553.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(41986..42082)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            42111..42542
                     /locus_tag="ACL3JB_000783"
     CDS             42111..42542
                     /locus_tag="ACL3JB_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0685554.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            42624..43001
                     /gene="mscL"
                     /locus_tag="ACL3JB_000784"
     CDS             42624..43001
                     /gene="mscL"
                     /locus_tag="ACL3JB_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0685555.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(43043..44137)
                     /gene="hemH"
                     /locus_tag="ACL3JB_000785"
     CDS             complement(43043..44137)
                     /gene="hemH"
                     /locus_tag="ACL3JB_000785"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0685556.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            44292..45515
                     /gene="pepT"
                     /locus_tag="ACL3JB_000786"
     CDS             44292..45515
                     /gene="pepT"
                     /locus_tag="ACL3JB_000786"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0685557.1"
                     /translation="MTYPNLLDHFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(45551..46204)
                     /locus_tag="ACL3JB_000787"
                     /pseudo
     CDS             complement(45551..46204)
                     /locus_tag="ACL3JB_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            46202..46366
                     /locus_tag="ACL3JB_000788"
                     /pseudo
     CDS             46202..46366
                     /locus_tag="ACL3JB_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(46443..47086)
                     /locus_tag="ACL3JB_000789"
                     /pseudo
     CDS             complement(46443..47086)
                     /locus_tag="ACL3JB_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(47193..47753)
                     /locus_tag="ACL3JB_000790"
                     /pseudo
     CDS             complement(47193..47753)
                     /locus_tag="ACL3JB_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(47979..51098)
                     /gene="phtE"
                     /locus_tag="ACL3JB_000791"
     CDS             complement(47979..51098)
                     /gene="phtE"
                     /locus_tag="ACL3JB_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0685558.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT        14954 a        10113 c         8121 g        18296 t
ORIGIN      
        1 agttgttcac cccttcgctc cacttccact acagaagttt cctcactact atgggctcgg
       61 ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct cacgggataa
      121 gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta caatgaaaat
      181 aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca catagacctt
      241 agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc tttttggact
      301 ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc ctgttcgtag
      361 agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca gacttaaaac
      421 ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg ggaatcgcta
      481 ttgggttcac cggtagcggg tgcccacgga ggacttacac ctcagatgca cgacatgccc
      541 gtcgtacctt aaaaagcctt ggaaaaaact gtttccaagg ctttctctat atttgtcctt
      601 attgaccaaa ccagttacat tgctttatcg tatctgtgat tttagtaata gcctcttcag
      661 tattattctg caaccataga tagcgacaaa cattataatt aaatttaata gaaaggttta
      721 attcttcgat tgtgtttaac ttgagttgat ttacttgata ctctaacttt tctctaattt
      781 cattaaaact ctctaaatct tcaatatcat aataaaaatt gaatagagta tttgcaactt
      841 gagggtaggt caagtcagtt acacttaact gagatagtac cttctccaat attgccacag
      901 cctcctcttt ttgcccatag aaataaaaat ctataagaga ttttatccac tccatataaa
      961 atttatttac cagagacaag cgatgtacct ttacactctc taattcatat atatttcaaa
     1021 gattcataat ttcgatttgt gataaatgtc tgggctaact ttttaaactc tgataactca
     1081 tcaatctctt ctacaatctg ctcattaaaa aaataatcta cactaacttt taacttctta
     1141 gacagagcat ataaaaagtc tgctcctgga gtaaattctc cattctctaa tcgactaatc
     1201 tgtccctgtt tacatatccc ctcagtcaat tctcgctgag acatttttaa ttcttttcgt
     1261 ctatttttta atctggttgc taatagtgtg cccaagtttg cattttcctt ttctattcga
     1321 tttcaaaaga tacaaattat atataagcaa tgactagata ggttattttt gaaaacctat
     1381 cccttcttct tttgaaattt tcttactcaa acgattgata aacttattca atttaaatac
     1441 gatgttctca tatctatcgc tctctaattc tatttggata cctaactcat tcaactcctt
     1501 ctcaacaaca tcaatgccaa ttttatcagt tatattcaac tttgaaagat tcattttcat
     1561 ttcttgctta ttttcaactg aagccagtaa atattctgct acttgattta aggttgtcac
     1621 tcgttcttga aaagcattga ttctcaattc agaagctgct aattcatgaa ctagttcatc
     1681 tttaattgta atataagagt gcttatccgt atccagctca agtaaagtat acacttcctc
     1741 aatcttctcc tttatcatct ccacagttgt tttcctgcgg aacggaattg tttgattttc
     1801 agagctgaat tggcgaatta atgttctacc tttcatatag caatttttct cggcatcatc
     1861 tttgtaatag acatagtagg agctcgtttc tctgataaaa accttcacct tatcctcctc
     1921 catatcgagc tccatgttag gcaaaaagat aagcccttcc tgacgaatac caaacttgac
     1981 cttgatgtaa ataccatcat ccactacttt ttcaatttga ttgagtgaca actctacctc
     2041 aaattcatga atagcatctc tatttctcct gaactcttga taggactccc aaaacttctc
     2101 ctcgcttggg agtctttttc ttttgagaat ctttcttctt gataaacttg aactaaatcc
     2161 tgaacttctg gagctttcaa atcttttctc ttctcaaaat aatctttgaa aaactctaca
     2221 tcatataagt ttttcttgtc tagttctgtt tctttcactt ctactcctgc aaattgaaaa
     2281 gaaacatgct tttgcttagg attgatattt aatccaaata gttttgcttt tttaatcaga
     2341 tcttctaagt tatcaacctt gggtaaaata aattccataa gctcttccat tttccttttt
     2401 gcgaagtaat tcttgaaaaa ttcttctgtg taagcttgct tgtgattgag tttattacca
     2461 cgcaccactt gtctcatagt tgagtccgtc ataaaaaagg tagcatgctt gtgactgaaa
     2521 tccatcttca catgtagtaa tggagcgttc tttttgaaat cctcaaaatc ggtagaattt
     2581 tccatcaaaa aatagagtcg ttgcttaagt tcatacttgt gattggtctt acgataaact
     2641 ttatactgat ggtaagaata gcgattctca ataatttttg cacctgcaat tttagaaaat
     2701 ctatctgaaa tcatgcgaag atttcgttcg actttataat tccactttag ttttttgtcc
     2761 gaattgttat caaccgaatt aacaatgata tgattatgga aatgattttt atcaacgtga
     2821 gtcgcaacga taaaacgaaa tttaccacca gttaactcct tcattgtctc atagccaatc
     2881 tgattgattt gtttaggagt gagatgatct tcgggtgaaa aggactgaat gatatgatga
     2941 gcatgaatta gtcgttgatt ttcctcatgc ctgtcgtggc gaaaatcgta aagcgtatca
     3001 ttactgataa aattttcatg atacatctgc accatctcct cataactagg aaaatccaga
     3061 aaattcctca tgccatagtg cgataccaat gcaagatttt cggtcttctc aggattgaga
     3121 atatacttga taattttttt gcgataacac tttccgtgaa cggcaaaatg cttagtgatg
     3181 accatgaaac tccctcaact ttttagcttg aatactaaac tctttctcta cctctcttat
     3241 caagtcagcg attccctttt tcaagtcttg caattcttca cttgaaatca actgagattg
     3301 attgacactt cgggcaatct ggttgatgtt attaccaatc ctcttcaact caaatactaa
     3361 atcttgataa ccagttgtat caatggtgat gaaattcata ccagggtcaa gtagagttcg
     3421 tcgagcatat tctgaaaaag attgacaacc gctttggtcg atacaatgtt tcaactgacc
     3481 caattcgcta tcagacagga aaactttctt tagattggtt cggtaacgat tttccatgtg
     3541 cctacctcat gtatttttta cggaagtctt gactaagagg aatggaattc cctatttctt
     3601 gaatcaattc ctgaacgcag gttaagagaa tggatacgtg ttcttgggtg acttgatgtt
     3661 ctgcccttga taagattaaa atctcataaa catcacgact gatttgttcc aacttttgag
     3721 ctcgccagaa ggtgaaccac ttttcagcag tcatttctaa ctcgttctcc agtaacttgt
     3781 ttctggcaaa tgaagaaaag tgttcaaatc ctttattttt catcattacg ccaatcattt
     3841 ctaattcatt tgcggtcaaa ttaacctctt tgcgaatgtc tctgtattgt tctggcatac
     3901 tacttcctca cttttatcta ttgtcggata attcccgacc ccgtgtcaac cacgggaaac
     3961 ttataaaaac aaaatctatc atcttgtaag gctttgcgag ctcagatatt gtgtccacaa
     4021 tatcccaaaa atcatatcgc cagctaatca aaacctacca gttttgacag ctaacgataa
     4081 gataacttgg tggctccgcc cccaaacccc cagtgaagat ttgaggtttt attttcttaa
     4141 gaatgatata agaatagcag agaaaatttg gaaaagatat cacaggagaa tgagaggatg
     4201 aaaaaaagag agcaaatgct ctcaatgaac tcatataaat atatatcaaa atactcttca
     4261 aaaacataag gttctaaaga ttatgtagaa aaagctttag caagtcttaa acactctgtt
     4321 gctctaactt atactggtcg atgctaaaat aatttaattc cttgaagtaa ttttccagct
     4381 tttaaatgat actcttgatt tttcatctcc tctaaacgac tatctacagc taaggcaaat
     4441 atattccata ttacattcca tcttcgtatc ttgttcttgt catataatct taaatgtcat
     4501 agagcatgga tttcatattt tgataattag gtattcctac caatgctcga ctagctctat
     4561 ttatcccttc aacataaccc tttgagtcat tcaatatacc aaaattccag aaccttttag
     4621 aattattcgg tgtctagttg taaccgtaat actcgtaaaa tggctaatgt agtacaatca
     4681 tcttcatttt ttatttttca actcctgcac tattaaaatc aatgtgccaa ttaattgcag
     4741 aacctaaaac acctgtaata tcaaattgca atctatcttg atttagacta gtcaaatata
     4801 tcttctttct ataaaatctt caaaagaaaa attcccattg ttgttactta ataatctatt
     4861 gatttcacta gtataaattg ttcgattatc aataattatg acttttgatt ttgctctagt
     4921 aattgcaaca taatgatctt caaatttcaa tcctgtgcgc caatcaatta gatattctac
     4981 aaaaattact acagtgtctg cagccaaacc ttttgatgca tgagtagtca ttaataaatt
     5041 attactcatt aaatttgtat caaacatttt tttattatcc aaattactca aaatttccaa
     5101 cagtatttga ctttctaact tatcttcata atttgtaatt gaaacatcta aatacgaagc
     5161 tatttcctca ataagtgact gtgtaggtcg ttgacgaagc ctctttaatt tttttaaaag
     5221 ttctttccta aattcatcgt tatattcagg aaaaagatta ttcaatacat catactcaga
     5281 aaagtcttca agaaaataat attgagccat agattgcaaa aaattactgt tagtacaatc
     5341 tataaatgga ttttttctaa cgtaatcaac tttatttgaa agaatatcat tcaaatgtgt
     5401 cgcagtttct tcaatatctt tattaattcc aattaaaaaa taattctttt cttgtaaatt
     5461 tatatcacca ttatcaataa ggtacttaat aatatcttct tttggataat cctgattagg
     5521 ttctaaatat agaattgaac cctcttctct aatattatcg acagtcactt caggagtcag
     5581 agctaaagag aaatccacta ttctaggcaa acttctaaaa ttcccaataa atctcttttt
     5641 tctaaaatca tttttgtttt tccataaatt atttatatat ttgggtgatg ctcctctcca
     5701 ctgataaata gattgcttat catctcctac aataaataaa ggaatcccta actcattttt
     5761 tagatacaga aataaatcat tcatagactg gtcacaatct tgaaattcat caatatacaa
     5821 agtattaaat ttatatttta tatattctga cgcagaatct attgtcttca aaatatctaa
     5881 agcaacttca catttgaaat tcttgccgtg tttagaagta ggaaagtcgt aagtcccgaa
     5941 aataccatcc tgcaatattt gttttattcc agtgctatag tcgctaaaat tatggtctat
     6001 ccgaaagcta aactgtacag atgtttgaat ttcgtatttc tgattaagaa aaggaaggat
     6061 tatttcttta tctaaaaacg aatctatggt cgatacaaca acgttgtccg gaatatcaac
     6121 taatttttgc tttatttcct ccgttgcatt tcgagtaaaa gttattgctg ctaatttttg
     6181 ataattattt aatcgtttag aatcactttt tagcttttta gttaaaaaag ttgtttttcc
     6241 cgaacctgcg ttcgctaaaa ttaaaatatt tccttggtat tctaacaatt cttttttgac
     6301 attcttgtcc tgtgtagcaa tatcactcat agtctaaaaa ctccgccaaa actttaaaat
     6361 atcctgattc cacaatctta agcgcaatct ctttagtaag atgattactt atatattcta
     6421 gcatattgta ttgtttactg ctttgtaacc aattcacaaa atctaattta ctcatttcat
     6481 ttctctcgct atcggataaa acctgagcta aatcattttc taaatcaatt tccgatataa
     6541 agattccatc tgcatttaat tgtaatacta gattatgatt agtcaaatat aattcttctt
     6601 ttttagactt tatattctgt tttctctcat cttttgaaga gaaatctata cgataattat
     6661 ctaatatagg agtcgcacta tgatcaagca agtcaataca cctatttaag ccaataggag
     6721 aaaatacatg tttatctcca cgactagctt ttaaatcatt atcagtttta atccaaaaat
     6781 caatccctaa tgccttatat agctctgaat aaggtttaaa atttattcca tcaacttgta
     6841 ataagtattt tccatcagcc tcgaaattgg gacttacata ttcaaaaata gcagaaaata
     6901 gataatattc tgatggacct tcgaccaaaa gaatcctatc ataaaagatt gactgagcca
     6961 acgatttatt taattttttc tttaagtttg aaaattcatt aggaactgtg taatagactg
     7021 attgccctgt tgcatcttgt tgattggtta tcttaatgag ctgagtatta tccatttcat
     7081 aaagaacttc tgctgaatga gtcgttagaa aaaagtattc ataaatattc tgaacaaaaa
     7141 gttgctttga aagagagatt tgaacggaac gatgtaagct attctctggc tcctcaatta
     7201 aataaataat taccttcttg ttgtattgtt tctctgaaat taaatggtta atagcatatg
     7261 ataaaagctt tttacgaccg tctcctgacg tcggataatt gtgagtatca tcattccagt
     7321 taatgtatgg tgtgagattg tctaaatatc ctgaaataga tatctctgat tgaattttaa
     7381 tttctaaatt ttctttacga taacttttat aggcttcagt caactgtgat tgaacactag
     7441 taatcaaatg taagttagaa atattttcat ttaatttttc aatgttattc tcaatctctt
     7501 cctcaagctt tacatcctca tcagttttag aatcatcaga gaacaatatc cttctatttc
     7561 gcttaaaaaa ggaatctaac tctatagcgg gatttacata aactatttgg aatattttat
     7621 caatgtcact tcttgtacca tattgaggaa cttccactaa attatctagt gttgagcccc
     7681 agcttaatac cggatttcca aataactctt tctcattata aactgcttct aatgagataa
     7741 agaatgtatc taagctagag ttatttcttg ctccagctac cgttgaaatt agaagacgag
     7801 aatgtgaaga ttttagtgat tcttcatccc cctccatttt tctatcagac aaatcaagct
     7861 caagttgtat ttttataggt ctactagtat catgtctata ataatccgat ttaataaaac
     7921 ctttatttcg tatagttctg tccaagaggt atcttattgc aaatagaagg tttgttttcc
     7981 ctgaatcatt cattccaaat ataacatttt tatttgataa agcaacctca atagaactaa
     8041 aattacgaaa attttcaatt actagttttt taaattccat aactattttt tccttctaac
     8101 tctttatgtc tttcttccac caccctcaac atctctttct ctacctgact ccactcccca
     8161 aagagtaact cttgaagaac atctgctgct gaagttgtat tttcttttga atcatataca
     8221 gaacttctat ctcgttggta aatttgaatt ctttcaaaga tagccagttc ttccaattgt
     8281 cgtgtattat caactagatg atttacaatg aaatcatgat gttcttttgg agttgcgcgt
     8341 gcttgatttg gattgataat gtacagttct tcataacgga taagagtact tagatacgac
     8401 aattcaggct ttgtcgcaat taaggccaat tgtacttcat atcccttatt tttcaagagt
     8461 tgtgctgttt tctttggaac atcaactgtt cgtaaagttc cctctatcaa aagattgtat
     8521 ctcaaactac taaattttgt tactaaagac tctaccattt ttcctgcaaa atctttggta
     8581 tattctacac tgtctttgcc atattcttgc tgcagttcta aatagtgtgg atgctgagaa
     8641 cgaaaactat caccatctat gataacaata tttccttgaa attctttctg tttaatacga
     8701 tgaattgtag tcttaccggc accactttga cctccaagca aaatcgctat aggttgctta
     8761 ctggactttt ttcctcttgt cagtgaacga agattccttg ctaaagcatg tttgaattca
     8821 ctatcagtat aatcttggat ttccattaag ctaccatccg cttttcagat atctctaaca
     8881 tacgttcaat tccatccaaa tagccactat atctctctat ttcatcaaaa gtttctacta
     8941 aatagatatt cgtatgaatc aaatcagaaa gatcatcact cattaaaatc caaggattag
     9001 attcatcatc aatgctaatt ccctgactat cttgatagcg atagagtcga gataatagat
     9061 tagcacctct ttctttcaca atttcaattt ttaaagtcaa ttcataatct tcaacaggat
     9121 tgagcatttt atcttctcct acgatatcga cataagatac attaaacttc tgacaaatga
     9181 tgtctattaa ttcggtagag actgaactcg ttccattttc ataacgactc agactatttc
     9241 gtgaaatacc tacaatccgt gcaaattcgt cttgtgttaa gtcatgtgtt ttacgtaagg
     9301 attttatgtt ctttccaatc atggcaaact cctttatttt tataattcaa ttatagcata
     9361 aaaaagcata atgcaccaaa aatggtgcat tatttcttgt ttttctatcc taaactttac
     9421 ttctataaaa gtcacctaaa gagccataaa tatttattct tgtattaatt ttttcgatgc
     9481 gcaaacgata tctacaaata catctataac gattcacctt ttaggatttt tattgtcaaa
     9541 attgccttta tctacaaaga caaaatgctt ataaaatagc ttgaaatcaa ggattatcac
     9601 ctttttcgtt gtagcaacac tccacatgtg attattaggc tattagcaaa gcgtatccaa
     9661 tacctcaata aagtgttgtt tttactgata ttttaactat attgtatagt ctactattta
     9721 aatctcaatt aggatatttt atagaatacc caaaattcaa caataactaa aagtaagatt
     9781 ccattgtatt tccttgttgg tctttcatat cacgaatttt atttttcaga atattaaagt
     9841 tacaaatttc atctctaata tcgttatccg ctctgtagcc attaatcatc tcagtcagag
     9901 ttttcccttt actaccattc tttatagtag tatttactct ttttatactg ctttcaaaag
     9961 gctcatatgt tttatactta attacttcgt ctttaaaatt aaataaaggt gtatccggct
    10021 tagcattcca taaaataatc aaccacatta tagcattata aagctacttt gcagtttcat
    10081 tccacttttc aggttgtaaa tttccactcc ctgtattgtc atattcttgt ctattattta
    10141 catgagaatc acctacaagc ggattaaaaa gaggtagccc tttgtgatta attagttcta
    10201 aaaatccctt gccgcaccca tgcaacactg tctccaaaat gacggtcaat ttcaaagtaa
    10261 tctgtcgtat tgtacttgtg attgcttgta gattcaaaga tgggacaaag atatagtcca
    10321 gtaataccca agtcttgcaa gtaatccata tgatcaataa tcccctgtaa atcaccacca
    10381 aagaaatcat cgctcttagg tgtgacagat gaatcccagt ctaaagtccc ttctgggttt
    10441 aatagagcat tgccattggc aaatctttca ggaaatatct gataccatac cgtatctgaa
    10501 acccagtcag gaaccttgca ggcatcaatc tcatgaagat aaggcaactt aaatccattc
    10561 ccaattgcat gaagattttc tagagaattt tccacacacc ctttatcgcc atacaaaata
    10621 ttttgacctt ctgtatctct gagctcaaag agatactgga tacgtgcaaa gtcaactgac
    10681 acttcaacct gccaatggtc aaataaggta ccagaagtta tcttgaccat ttcttttgta
    10741 tcctgataaa actcctccat aaagataaaa gggtccccat agtgcaagtt aatgctttca
    10801 atgtcccctt tcttagttcg aattcgaata tggagtttct tatccttata aagataggca
    10861 tactccgact caggcctatg gtaaatagca ctcaattcca tcaatttgtc tcctaaagta
    10921 ttcattcaaa ttttacgcaa acgttttcaa actcaataaa tccagtatac tatttttgta
    10981 aactatttac aaggaatgtc cgttgttaaa ggaactatct tttaaagtat acaaaaagcc
    11041 ttaaaaaggc tttctctata tactaatcct ctttcggttt tgaaaatact tctactcgct
    11101 gagctaggac tttgatttct acaggtaggt tatctgattt atctccgtca acatctgact
    11161 ccaattcact atctgaagag attttaatat tacgcgcttt gatatactcg atattatcat
    11221 ttgcgacaac atcccctttt aataaatcag gaatgacgga taatttggag aatatagagg
    11281 catctttcag aatcaaaatg ttggcatagc cgtccttgtt ttcttcaaag gttttcttat
    11341 cagcgaagta atttgtcaaa aggaccaaaa catggctagc ttcaccaaca taatttccat
    11401 tttctgtctc aaccttaata ttaaagacct gatctgtcat gacagacttc atggtattta
    11461 cagcataggt taaaataccg aattttgttt tgtcctctat ttcaacattg tgaatcgcct
    11521 caggcagaga accgatacta aagatataac caaaatagtt gtcatttgct ttaccgatat
    11581 caatcttatt ggttaaatca aaatccagtt cgtcaattgc gccatcgatg tcttgattga
    11641 tttccaaaag ttttgtaatg aggttacccg taccgcctgg gataatccct aacttaggaa
    11701 tgtagtctct ctcatcaata cctgaaatga cttcattgac agttccatct ccaccaaaca
    11761 caaccactgc atcatactgc tcacgagaag cttcttcagc aaaatgtgtt gcatccagcg
    11821 ctttttcggt aattttggtt tcaacatatt caaagtattc ttttgcttta ttctccagct
    11881 tttctttgta atccaaagcc ttctcgccac cagaagtagg gttgataatt accattgctt
    11941 ttttcattga ttttatcctt aattttaaac agaaatgttt acatttcgtc gtatgcaagt
    12001 aaatgtaatc ctattataca atgaaaatac agaaaagaga aatctgacgt actggagatt
    12061 aatacgcttt tattctattt tcccatcgcc taactacatc ctttaagggt tcatccaagt
    12121 aagaataggc cttatccttg atccaatcag gaataccgta agctgcctct gctatgttac
    12181 aagtgattgc tgcgagagta tcactgtcgc caccaagtga gatggcattt cttatcgcat
    12241 cttcgaagtc tctactttca agaaaggcga taatggcttg agggacagtt tcctgacatg
    12301 tttcgttaaa acgatagtta ggacggattt catctaaagt ttgagataga ttgtaatcgt
    12361 attctttttc tatataatcc ttaattcgtc ttttacactc tgtaggattg tcgttaattg
    12421 attgctcgta ctctctacaa taaccaccaa agtaaaaacg acatagaaag atagcatcag
    12481 ctgtagccat agcgcctttg acaccttctg gatgattatg agttacctct gcagaaagac
    12541 tcgtaagtcc tctagatgat ggccatatac cagttttcgc ataaaaacca cagtccatga
    12601 tccaagcaca tggagaaata cgcatagctg atccattacc aaagctatta taaggctcac
    12661 ggttatcgct gtttagccat gcattaaacc gagcaccgta atcagcattc ggatacattc
    12721 tgccatattt cttcatcgcg tcaatgaagt cgtctttttg tccaccattc ataattgctt
    12781 ctgcaacagc acaagtcata accgtgtcat ctgtaaaaaa gcagtccttc cgaaataaag
    12841 gaaagtcctt tgttttgata ttgttccatt cgtaaacaga accgacaata tctccaataa
    12901 ttgctccaag catcagattc ctccttgttc attttgatgc tttttatatt ggttatctac
    12961 catatttatt ttagaaaata acatcctgtt ggattttaaa aatttcattt ttttcaaaat
    13021 agggttttac catttctttc cacctagctc tatgaaaatt gattgatttt aaaggagata
    13081 ggccataatt tcccaatgca taaccatcat ttacttcaac aacaagtgtt ctgccatcgc
    13141 gagtaacacc gatatctagt ccataagcta ttggcgcatc tttccaacat gatatcgctt
    13201 catcaattac acttgcatca aattgtgcat gataatcacc tgtatagggt cgaacatcta
    13261 atacgcgacc atctaacaca aaacaacgcc attcagctat gaattctaca acctcactaa
    13321 tccatatagg atagtcgaaa ggtagaccaa tacctattaa atcatgggtt ccattaacaa
    13381 ctcttccagt aaagactttt gaaccagctt taggcttaat aaattttccc caattatcag
    13441 gtatattcac aatctctcct aaaataccaa cataaatctt tcgaccataa aactctttaa
    13501 gctcaatagg atagtcataa accggaacgt ttaagcccat catttttagt aatgctctag
    13561 tctccattat ataatctaca actatatctt cacttgttaa ctcttttatt tcataaaaag
    13621 attgatataa aataacttct tctccttgta agtaggcacc tacttgagca ttgtatttat
    13681 taattgaaac ctcacttggt aatttacttt gtctaatata aacaaccatt tcatcactcc
    13741 tgtatcacta gtgttacacc aatttgtaaa aaataatagc aattttgctc ttattttttt
    13801 gagtaaatag cccccataat atcatcgaaa taatcaacgg tatttaggag taattcaata
    13861 acctgggact ttgttagtcg cattcccctt ctatctctag catcttctac taaattttca
    13921 agtttctcta gatttttatc atccaagcta atcattattc tatttttatc ggttgccatt
    13981 ttcatcacct caagttaatt ctatcacagg tgtaacactt gtgttaactg gcttttataa
    14041 tacattagtt taaaagtgga gaggattttt tacacagtaa ctttaaatct ttggtattaa
    14101 aaaattttca caatatttat agaaataaaa tctgtctcaa atcagttatc aaatctagta
    14161 taaattatga gcggctactc taatactttc cctctaaaca agaaaaagac ttacactcaa
    14221 ggattttctt cccccccctt cgttataacg ttttgactct tttactagca aaggtatata
    14281 ctcacaagga actttggttg actattgaat ctctccaact tcttctttaa catatccttc
    14341 tacatcttca atctctacaa acattgggtc taagtgacac aagaaatgcc aaacttcgat
    14401 cccttttttt ctgtaaagaa tcgcttcacc gtcttcactt ccgaaaaagc ttctgtcgat
    14461 ttcatatccg cggctttcta agaagtcttt tgctttacga tagttcgttt ctcttgtttc
    14521 gacataggct ttaacttcat ggttgttaac gacatatgca tcaatttttg aatatccttc
    14581 gatcactcta tcatttttga gggataaatt tgaaatctct ttccaaataa tgtttacatt
    14641 ttccccagga tcgaacataa atttagataa aggaacaata tttccgttaa aaataatttc
    14701 catataatcc ggtatgtttt taggattaaa atactccact tcaaaaccat cttctgtttc
    14761 cagagtgtat cccgggattt gagctacaaa ggctttccca tcttctatgg aatcaaatgc
    14821 tactaaatct ttagaataat cattttggta caattccaat ataaccatcg ataatctctc
    14881 cattttcatt atcaggctaa tgtaaataag cacgtcacct gaccaattca ggctctctgt
    14941 atcatctcat catatttcct acttacttta cgagtcctat acccagaaca caccttatcg
    15001 accttcggtc tcacctcgtt gcattggctg aacatctact tttacttcgc tgatgcttca
    15061 actcgtacaa gcagtgatac cgcctcagcg tgatgcgtca gtgggactca aaaggttcgg
    15121 ggaacctttt gaggattaac tacgtttctc taataaactt acacattcaa cttgttcatc
    15181 attgtccaaa cctatgttga gattttcttc tataattggt agcttaaaag taatggattt
    15241 tagccattgt ccgttagatt gtttttcttc ataaacttga atttcagaaa tcaaagctga
    15301 aattaactgc ctacgctcta catcattcat gactttatag agcttatcaa aatagatcag
    15361 aaccttatat atgttatctc ctgtaagctt ttcagcttca atagtctgtt tctttgcttt
    15421 cgcatcaatt agtgatgatt ctaattcatc tattttgtca tacatacgat atagtctatc
    15481 atctaaatcc tgtttccttc tcttatagtg cttatcttca acatctaaat tatctatttc
    15541 ctcaattagc ttaaactttg tagaatgact ctttctcaat tccttttggt aattatctat
    15601 ttctttttct atttcagagg tatccacctt catgttgatt ttttcttgca tcatagaagc
    15661 aaatttcgga ttacttacta tcttgacaat cacctctgca acagcatcat ctaacaattc
    15721 ttctctaatt tgcttactga atgtacactt atgacctctt atcatctgcc tatgtttaca
    15781 accatagtaa taaaaatctt tatactttgt gccatctttc tttttcttga tacacttgtt
    15841 cccaaacatt cccactccac atatccggca ttttacaatt ccagaaagca agtgtgtgcg
    15901 tgtatctttt cctttattca catgctcata tttctttgct tgagatttta gcttaacctg
    15961 agcagcttgc caaacttcat cggaaactat agcttcatgt atcccttcag atattagata
    16021 ttcatcttgt tcaacctgct tatattcatt tcttgtacca tgaacttttt ctaaagttct
    16081 tcttccaaat actattttcc cattatatac aggattcttt aatatctttc ttataagacc
    16141 tgcatcaaac aaaggattct taccattctg tcttgggatt tttctaattc catgattctc
    16201 taagtattta gatatcccat tggctcctat cgtagtattt acatactggt cgaaaatcgt
    16261 tcttattgca actgcctctt cctcatttat aaacagcttg ccgtcttcaa gtttatatcc
    16321 atacggagca aagccaccat tccattttcc ttcccttgct tttgaatgcg accttccatt
    16381 gtttgaatac ggatgttttc tctttctatt tcagccacag ctgataaaac agaaatcatt
    16441 agtttcccag catctttaga tgaatcaatg ccatcttcaa cgcagataag attaactcca
    16501 taatcctgca ttatctgaag tgtagaaaga acatcagcgg catttcttgc aaatcttgat
    16561 aacttaaaca caagaacaaa agatactcca tcttttccag attttatatc ttccatcatt
    16621 cgattgaact gtattctacc ttcaatagac ttgccagact tcccggcatc ttcatactct
    16681 ccaacaattt cataatcatt gtaaatagca aaagctttca ttcgtgattt ttgtgcctct
    16741 aacgaatacc cctctatctg tattgacgta gatactcgtg tatagaggta tacttttatt
    16801 ttttcttttg acatagtatt aacctcaata taatttttct atatcatata taattttttt
    16861 aatttaagtt tggactatca tttcaagtat attataacac ttttattagt ccgtctcaat
    16921 ttgtgttttt gccatgtcaa aactattttt catctcttga ttttttgctg gcgttggatc
    16981 gggtagatta tctaaatcta aagcaccagc atattttgca atcagatttg ctattaaatc
    17041 agccaatcca ttccagtcat tgtccaatat atacctcctc taaagtttta tatctaataa
    17101 ttatttgttt aattaagttt tttgacattg acaagtgctt tggattagca acataggaat
    17161 ctcacctccg cctctattcc ggatgagccg gcttcaacct tagaagtatc attatcctca
    17221 ttttcttcat agcggatagg gtatccctcc ctatattcaa actcttactt atcgctcact
    17281 ttctttttgc tcagcagaac tttttttgcc gaattattca gccgaaagat cttgacggat
    17341 aggttattac gctccaaaaa taattaacgt cttgtcttgg tctattcaat tgttaaggtt
    17401 caaaatttat cgagagttat taatcttttt aaaatttgac catcagaaaa tatttatctt
    17461 gatgtaataa aattctataa attaccctct tatacttaac agtgaaaaga agtctttctt
    17521 ggtaaccaat tttgaaatag aatttgctta tataaaaagg tccaattcct actgcataag
    17581 tagcagtgaa aattagaccc tcttggtaac tgtcatctaa aagtcttcta gcatttcttt
    17641 aattttctaa tcgcctttaa agtgtcatat ttatattttt ttatctctgg catactttga
    17701 taccttttta gacttaaagt ctttaatagt gcctttccac ctctttttat ctataaagat
    17761 tctcctacat cataattcat ttttttattt aaacctttct gtcttagttt gtctttatct
    17821 tcttcatacc attttaagat tgtcacatag tggttttgat aggtcttacc actgctttcc
    17881 atgtatctgg atagtttatt tatcattata tctgtgtgtg agtttaattt ttcttttaga
    17941 tttttatatt cttctttgct taaccttaca tttttgaatt ctccataaaa aatgggggtg
    18001 gactttttat ctatctctcc ctctctctct ttatctatct cttgtcggac atgggttgga
    18061 ctcattaagg acaatgttct ctgtttattt tgtctgtatc ttcttttttt ctctgcccag
    18121 gctgtttctg atccgattaa gtttggtatt tcagttaggt agtattcatc attttctgtt
    18181 acaacttcta ataagccttt attgattaaa taatttactg ttaccattac atcatcgtct
    18241 gtttcatcta tggttagtgc taactctttt ataaaatcac tttctactcc gtcataatag
    18301 agtttgccct catcttttag gcttagtagt agaagtttta ggtagattat cgtataggta
    18361 tctcctccag atattctcct taaccttttt atccttttgt ctgtgaaaaa ttcttctttt
    18421 aattttatcc aatagtatct tttgtttgtt gccatatctg ctcctttctt gattttcgat
    18481 aatcgaaatt cttgatttcc gattttcgga attctggact tctgtttttc ggaagtcttg
    18541 ttattatggt tatttaaggg tgtaactttt cgttactccc tttagatttc tctggtcata
    18601 tcttttttgt ttggttttac tttttctttt actttccttt ttcctttttc ttttgtctta
    18661 tctttgtttt tggataggtc tttgtatttc tttatttgtt ttaggatact ttctttttct
    18721 tttttatttt ccttggctat gacttgctta aaggcatatt ccattacttt tatgtctttg
    18781 gcttggaaga atatttcata gtttttgctt tctttgtttt tcattactga gaaacttact
    18841 ccaagtttgt ttagttcttt ttttaagtct ttgaggtcga tttgatctat gcttatattt
    18901 tctagttgtc ctttcttgta gagatctttt attttcattt catcgcccat aagacttttt
    18961 aagtttccat ttgctttttc taaagtttca ttcatctttt ttcttatttc tttttctaaa
    19021 ttgattgatt cttttgttgc ctttattgtg tatgatatta tggtttgtgc tgcttgacct
    19081 gcttccttgc ttatttcttc gtttatcatg cttttctctc ctttgtttga attaaaaaag
    19141 ggaagtatag gttttaattt ttctatactt ccctttgctt gtttttattt tattgttctt
    19201 ggtggtggaa tactttattt tgatgttttt atatatttct taggtctttg taccttttat
    19261 acttttaaaa atagcttaca ctacctttcc acctttaata gtttatgtgt gttcttttgt
    19321 ctgatagata gtttttcatg ttggaatata taatctgtat ttcttcattg ttcattgctt
    19381 ttatttcttc tgtgctttta taggttttgt atgttccatc ttcatttgct tttatgagtt
    19441 catctattag ctcttgcctt ttattcatct ctattacctc ctagatctga ctttagttgt
    19501 ttggtcatat tatagcttgg ataagatatt tttaccaggt cttatctttc ttgatccatt
    19561 ttcttgtttt tcatcatttc tctgtattca ttatctttat tgacttggtc ttggaacttt
    19621 ttaatctgtg ctattacact tggtttttct ccctgtttta ttagcttatc tatttctatg
    19681 gataaatcta taccaagttc tttgtttaca aaatctactg aatattttat atgattaatt
    19741 tcctggtatt catcttttat cttgtctttt tctttattta tttcttcaag attttacatt
    19801 aaaagaattt tttcttcatt ccacttttta ggacttagtt tttccttatc tgataggagt
    19861 ttttttaatt tcccgcttac tactttatat tggtctatat ctttcttatg tttgttataa
    19921 aatgcttctt ttgtgaatat atttttcttt tgatattctt cataaacttc ttttttggct
    19981 ttgtagattt catagtatag aattttcttt tctacatctt ccatttcttt atggattgtc
    20041 tttgcttttt tatttagcct ataactatta gactttaaag tttctatttt tgtttgtaac
    20101 tgacctatgg tttctatgtt gttttttctt aaataactat atgcacttgt tagctttttg
    20161 aagtcatatt tttctttatt agtttttgca tatcctttta gatatttact tttttctttt
    20221 tgaatttctg aataagttaa tagataattt gttagattaa aaagtttagg gttgtctatt
    20281 accttatctc tttcgatatc cttaaatttt tcataagcag tagataagtt atctaataaa
    20341 tttcctatcc aaccctttaa tgtttttatc tcttctttta ttgtttttac aagttgatta
    20401 tattttctta tttctctatt atagtttccc ttgtcagttt ctattccctt tctttccatt
    20461 gcacttgctg ctgatcctaa atggattgtc ggtagataat ctgaatttta tcttttaaaa
    20521 ctcctatggt ctactctttt ttctgctcct gctctttcta aatatttgtt acaaagatct
    20581 gaaaaatttt ctctccattt ttctacattg cctgtatcgt tccaggttgt tagttctact
    20641 tttcttgtct ttggttttcc atttttgttt aatacttttt ctcctttttc atctaggata
    20701 tattcttttt ttgacttggc taagaactct cctttttcgt ttattggtcg cattatggtc
    20761 attatatgac aatggatatt tccattttta tcttgactct catcatgaat tgcataatct
    20821 actatcattc cttgtgatgt taaattttct tttatatatc tttcaaccag gtttttattt
    20881 tcacttaaag ataactcttt tggtagtcct attatgaatt gtcttgctag ttgtgcatta
    20941 gaattttttt ctgccatttc tactttattc cataagatag acctatcatt aaattctttt
    21001 ggtatatgat caggcaatat tatatttttt actaatattt tttcttttct tgtgtagtca
    21061 tgggttactc cgtcccattc attttttatt ttttctccac ttatatatgc tgcacttgct
    21121 actgcacttt tgccttttcc tcttgatatt atgtttactg aaaaatgaaa actgtctgcc
    21181 atttttatca cttcctttct ttctttgttg ttttaggtgg aggcttaata gtttttttat
    21241 atcctctttg tgaatgagcg ttttgaaatg atagaattaa aaaagccgac tactgaatta
    21301 atttttgttg tttcagtatg tcggcttaat tgttactttc atttcaaatt ttaaaagtca
    21361 agggcgagcc ttagcgagtt tatttaccct tgacttttaa aaagcgaatg gttgttgctc
    21421 cctgcaaggg tttgactccg caggacgcaa gtacccttta gggtgtataa ttgcgccctt
    21481 gtaaccaagg gacaattatg ttatttcatc tttagatgat ttttctacat tatcatctat
    21541 tctttcttct aaaatttcca ttatgtttaa tcttatttct tcatcattta acgtttttat
    21601 taacttataa aattcatctt ttgttaaatc aatactttct tcaaaaatac tttcaaacac
    21661 tgcacctttt tctataagtc ttttgtttct tgcttttctt tcttgttcat taagtttttt
    21721 cttcaactgt cttttttgat tttgtaattg cttaatgctt tcttctttct tttcaatctg
    21781 ttcttcaata cttaatcttt tacttgccat catgtatcct ttcttaaaat aaaaaacgac
    21841 tagattttta tttctaatcg ttcttgtttt aaatattata atttgctata ttgcatttta
    21901 attttaagtc ttctatatat ctttccatgt aattccaatc tggagtacct ctactgtcta
    21961 tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct ttatattcag
    22021 tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct ttattcaatt
    22081 ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta tatttatgat
    22141 aaaagactgc tcctaaaaat gaaacagata taaaattttc aaagactcta taatttttat
    22201 catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca ctaattctag
    22261 gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt acttaactcg
    22321 atttcccctt tttttcggta ataaatattt ctttttattt tgttgtctga tatttttcct
    22381 acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt tacttgaagt
    22441 tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc tgatcttttt
    22501 aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt actaatttta
    22561 tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt agttttttgg
    22621 cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattcca atattcaatt
    22681 attaagagtt aatatggtgc ttgccaatag gaatcattag aggcgaattg gaaatagggt
    22741 cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca tttagtatat
    22801 cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg taatcagcgt
    22861 atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt
    22921 ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag taagtagttg
    22981 gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc catactcttt
    23041 gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca acattggcct
    23101 taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta aaaggctttc
    23161 tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca gggattattg
    23221 gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa gaattaattg
    23281 atttattatc aagcaatact tctccctcta atggctttat aagtcgagac aaggttttaa
    23341 tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt tcttcaggta
    23401 tttttatatt tatattttcc aagattattt tttcatcata accgcaggta agattatttg
    23461 accacagacc tttcattata tattcctcct gttcattttt attagtaagt atattaaata
    23521 tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta aaatattttg
    23581 agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta atattgggct
    23641 tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac aagctattgg
    23701 tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta aaacaagcct
    23761 tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt caataatttc
    23821 tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta ttagaacaag
    23881 gggtatgtca tctaactttg taaaagataa agagccactg agccatctca taacttcttg
    23941 taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg tgacagcttg
    24001 aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa
    24061 aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag tagttaaact
    24121 atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc
    24181 gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa atcctgccaa
    24241 tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa tttccataat
    24301 cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag ttgaaaaaga
    24361 ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta ttaataaaaa
    24421 tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa ttaaattttg
    24481 cattagttat taacccctct atttttcata gttacataaa taagtactgg acccccgatt
    24541 attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg gccgattata
    24601 tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat tgtgcgtata
    24661 tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa gccaataggt
    24721 ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc aagtgatctt
    24781 atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc taaagcgttt
    24841 aaatctgatg aaataaatat agctatcaag tgacctaaaa ttataaaagg tagtagtgta
    24901 gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct aaatttgtct
    24961 aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc catactaaca
    25021 caagttcctg ataaggcaag ttttataggg gtaaggcctg cttttccgct tacagcaatc
    25081 gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat atggcttatg
    25141 cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc tcctgtgttt
    25201 ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat caatacaccg
    25261 cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat tcttttatat
    25321 ataattgatt taataaaatc atcatttgta ttacccattc caaaagctgc taaaaaatct
    25381 ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat aagaagacct
    25441 aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat ttttgcatgc
    25501 atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg gtgttggagt
    25561 gcatgaggct gctaacggtg tattatctgg aattacagca acggcaccat ttttaattgc
    25621 atttatttta cctaaaagag gatctttttg taaagcttca agagttttat catcaccata
    25681 agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa tttcctttgc
    25741 aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac ctaaatctgt
    25801 taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg tatctgcagc
    25861 attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt ctggatgttt
    25921 ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac cttctttttc
    25981 catacctaag gcttttgaat caattttaat catatctctc cataaagttt gccaaggttt
    26041 agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt ctttagttat
    26101 accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt caaagttaag
    26161 tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt tttcttctgt
    26221 ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa atccaacagg
    26281 aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg caactctttc
    26341 aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt tatcaggcgc
    26401 atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag cgctaaaaac
    26461 tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa ctccttaaac
    26521 atatttcaag tctattgtat cgataataat tatcattgtc aatagatgca gttacaaatt
    26581 taataatata attttttcaa aaaaggatct agtttttatt tttagttaaa ttatgtctat
    26641 atttttcatt aactcatcaa taaaaatttg tttgctaata tctctttctt ctgattttgt
    26701 ttcaaggatt attgctacat cattcatatt tttaggtaaa taccaaccat ctggcttatc
    26761 tgaatatccc ttgaagccta attgattaaa agtagttatt tgaccagtac cttgattgat
    26821 gttttcttca acttcattaa agcctatact tctcttgcat aatccctaac ttgatcttct
    26881 gtccttaaag tcattttcta ttcctcgtca ctaaaattat cttcaaaact aataatatca
    26941 ttaggagtgc aagataaagc cttacatatt ctttctaaat tcttaaatgt aattggttta
    27001 tcctttccca tttgtgccat aacatttgtt gtaagtcctg ccatagctat tacatctgtt
    27061 ttctttagtc ctttttttgc taactgtatc cataatggtt tatagttaag tgccataata
    27121 tccctctttt tttcttcatt agatttattt aattatagca taaatattga tttcattcaa
    27181 tcttacattg atttagtgat ttgttttaga gaatttgttg tgttattccg tccttatttt
    27241 gccataaatt gttttaagtg ggacctctta tccttaccat ttttacctcc taattttgag
    27301 tataaaaaag acgatagagt ttttaatttc tatcgtctga gatttacata ttaaattttc
    27361 atcacaaaat aagactcttt aaagaatctt taaattcatt ggtatgctgc ttacaatatc
    27421 cattattaaa atggatattg taagcagcac accaactatt tattttttga gttttaaact
    27481 ttggtagaag tcttgaactc cttatattta cataactatt tgcctctata actgttatga
    27541 cacgaaacca acaagcaagt tcaaacacct ccatatcttt attcaaatga ggactaagat
    27601 attcacaaac tttatcataa acctctttat cttttttcat aaaaggggca tacaacttag
    27661 caaatttatc ctaaaatttt ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat
    27721 aaaaatgatc ctatcaatct ttatattgat cctattttct aattgatacc ttgcaagaaa
    27781 ggaataatag ctgttcctat accaagtagg aatgtaataa atgcagaaag tcatatactg
    27841 tcattctttt ctattaaatc attttgaagt gtctcaaagc atccatgatg gcttcttctt
    27901 tttcaggtgt acactgtgga ataatttgtt tatccttttt agacttgttg taatgttctc
    27961 gtaattctat tccacatttc ttttttatct gtgcaatata taatgtcgaa acttttaatt
    28021 caaatttatt ccaaacatat tctttgattt gagcatatgt tgctttgctc tccgcacttg
    28081 tcaaatccag ctcaatttca acacttatgt gcttatcgac atcgagtttg gacaaaagtg
    28141 ctaccgtctc gacgtgatgc gtttgaggaa atagatccac cggctggact ttcttcaatt
    28201 catatcccaa ctcttggtat agtttaatat cacgcgccat ggttgcgaca ttgcaggaga
    28261 tataggcgat gcgatcggct cctgtttggg cgcttgcttt gataaagctt tctgtcaagc
    28321 ccttgcgtgg aggatcaacc aagataacgg ttggttgaat cccatcttta agccaattct
    28381 tcatagcatt ttcagctgtg tcacagacat agtgggcgtt tgaaatattg ttcagctgag
    28441 catttttttt actattctca accgcttctg gaatcagttc aacaccgtag acttctttga
    28501 catgcttggc gactgataaa ccaatggttc caataccaga ataagcatca ataaccacgt
    28561 catctttttt taactctgca aagtcaatgg ctgtttgata gagtttctcc gccatttcag
    28621 tattgacttg gtaaaaggct gggccagcga tttggaagtc atttcccaac atctggtccg
    28681 taatatagtc ttgaccataa agagtgcgcc actccttacc aaaaatcgca ttggtattct
    28741 ggtcgttgat attttgcatg acagacacaa tctctgggaa ctgcttgata acttgttcaa
    28801 tcaattggtc aacacgaaaa acttttggac gagttgtcac caaaacgacc atgatttgtc
    28861 ctgaatagtg accacgacgc accacaagat tccgaatcaa tccagactgt tccttttcgt
    28921 cataaggttt taaatcaaaa cgacggagca ggtctcgaag agctactacg acttggtcaa
    28981 tgacaggatc ctggataaag aaatcttcaa ggggcatgag gttgtgcgaa ttcttacgga
    29041 aaaatcctgt ttccaagaca ccattcactc gacgaacggg cacctgcgcc ttattgcgat
    29101 acttgactgg atgttccata ccaagcgttt cagcaacttc tacatctgca attccagcaa
    29161 tcttgtagag actgtccttg acttgcttgg ttttaaactt gagctgttct ggataagaaa
    29221 ggtgtcctaa atccgcgatt cctgaacgca ggtaagccaa atctagatct tgattacggt
    29281 gtggtgactg gacaaggtat ttttcaactt ttccaaagcc aatcttttta ttgaccttga
    29341 ggacacgcat gagaattttt tcactcggta aagcattctc tacaaaaaag accaaaccat
    29401 ctaccttggc aactcctgcc ccttcatggg tcaaatcaac aatttcaact tctacaatat
    29461 catttttctt taacattctt ttctctttct attggccgac aaaaaagacg gcaacgttac
    29521 ggttaccatc cattatacca tgaaatttct taagaaccaa aactcttgaa gaagttgaca
    29581 agggcttgcc agagggagct taagaagtta ccaccgtcct ctagcgcctt atccgcatca
    29641 aagttaaggt tgatattttt aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg
    29701 tcatttaggg ttttagtgaa atctgcattg ctgaggatat cactctttga gagattcaag
    29761 gcaaaattga tgatgatatt gatctggttt cctgttatga cctgatcaag tttgtaattt
    29821 tttaaggtat cttcaacaat cttgcggaca tcttcttctg tcagatttcc cttgctttct
    29881 ttagctttgg caagtcctga cttgatatca gctagggcaa cgtttaattt attagcatca
    29941 tagcctgatt tgtccttgtt ttcagcattg atatctgaca aagccttcaa ctcttcttga
    30001 gccaaatctt tattagcttg tggcaccttg gctccattag cctctagcga atagtaaatc
    30061 cctgctaagg cactttctcc tgtaaccgga ataggggctg ctacagtgat tttggcatgt
    30121 tccataccca gcgttactgc tgcgtttcgg tacatatcct gagtcacctt agtgatattt
    30181 tctggtgttt caatcttgac ctcaagtggc gatttgtcac ctagcttttg aatcttggct
    30241 gatgaataca actgtaagct agagtcattg gccacattca tgattttaga ataaacatca
    30301 ggtgtcatgg tcttgagttc tttggtatct gttgaggcat tgtagcccag ttttttaaga
    30361 gtttgatttt tttggtcttc agatagggaa gaacctagga catattcagg ttggacatag
    30421 gtttcatcga taactttttg aacatctgtt gctgcatgaa cgctattcat agctgttact
    30481 gcccacaaga tcgcagcgct agtcagaaag agtttctttc tcatagggaa ttgcctcctt
    30541 tacttcttta gagtaatata tctatcttaa agaaaactta taacaaaaac acctggtcta
    30601 gccagatgtt gaaaagagag tgaaacattt gatgatgtaa aggttaagtc gtacctgtct
    30661 agaataataa tagtttcctc catttacata gagttcagca ccgtgaaaaa tggaaatggg
    30721 gtgaatataa ctataagtct ttccagtcct attaccaagc aagggggcaa cagtctcacg
    30781 agagtactgt ttggctagag ccagggtatt ttccttgcca ttttgggcga taaaatcgat
    30841 ataggcaggt ccaaaattat aggcttgaac agctgtccag atatctacac ccttcttctg
    30901 cgccagatag agattgcctg tcagagtttg aatgccttgc cgaatgctag aggcattatc
    30961 attgatggtg ttggtggaac cacttgcaga ctcactagac tgcataacat cgccttcttt
    31021 tccttttgtt tcagtataaa tcatagcaag cacaagctct tcgtttgctg gggtgtcttg
    31081 ttcactcaat atttctcgca ccatgggttg ataggtcatg acttgtttga catcttgatg
    31141 aacgcggtaa gctttatagc cagcaaaaag gaagactgct agtacaagca ctcttcgaat
    31201 tcgtttaaac attatttact ttggatatcc tcgatatttt tgattaagat agagtaggtt
    31261 ccattttcgt tttggataaa ctcaacagac tcggcgtctt gatagacgtt attgggaacg
    31321 atgagctcaa ttccatttga taaggagagt ttttggtttt caaatttctt taattggcga
    31381 ctggcatcaa tttcatcaaa ttgaacaggt tctggtacgg cttctttgac ttggtcaata
    31441 aagctcaaac gagccgtcag attgttgtca aaaaggtcat tagccaattt ctcaggtgac
    31501 aattcattgc tttcttctag gttgttgaaa atagctgatt tgaccttgga ttgaaattga
    31561 aaatcatctg tgttaaaaga ttcagcaatt ctctgggctg ttttttccag ttccttgata
    31621 gattttttag gagaaatctt aggagcgaca gcaagaagat tatctgaaaa atagttcaaa
    31681 aaagtcccgt tgtacttgat tcgtttttca atcaggtgat acttgcgact ctgaagattg
    31741 accaccaagg cctcgtcagc acccgttcca aatccaggca ggttattctg agtcagcttg
    31801 attggattat caacttctcc tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag
    31861 aaagcgaaat gttctacacc ttctttagaa aattgaacaa aaatcaagtc attggtcttg
    31921 agattttcag aaatgctaaa ctcctctttc caaagattag ccagcgttac tgatgtctcc
    31981 aacaaatcgt ctgtaatatg attgaagaag ggattttctt cttcgaaaat cccagtcttg
    32041 gcttcatctg aatacacatg ttcaattttt ttacgtaggt attcttcgat ttttggagta
    32101 atattgagaa acttatctgc taagaacagc tcggtatcat ccggactgaa ctggtgaata
    32161 atggctttct taatataaat gtccataaaa gttttagtcc tcgtataatg ggaaggcatc
    32221 tgtcaattct ttgactgcac ttctcacttc ttctaataca gcctcatttt ctgaattctt
    32281 aagggtttta atgatgagtg cagccacttt gcgactttct tcttcaccaa atccacgtgc
    32341 agtaatagct gctgctccga tacgaatccc acttgtcttg aatggtgaca aggtttcgta
    32401 agggattgaa tttttattta gggtaatatt gacttcatcc agcaagtttt gagcaacttt
    32461 tccgttttct acaaccttag tcacatcaac aaggaagaga tggttttcag ttccacctga
    32521 aataatacgg aaatcagggt cttgcaagaa gacatctgcc atagccttgc tgttcttaat
    32581 tacattggca gcatattcct tgaaggctgg atccaaaact tctttgaagg aaactgcctt
    32641 agccgccaca acatgctcta aaggaccgcc ctgaatacct gggaaaatag ctgaattgat
    32701 ttttttagca agttcttcgt cattggtcaa aatcaaacca ccacgaggtc cacgaagggt
    32761 tttgtgggtc gttgttgttg tgatatgagc gtatggaact gggcttggat gaaggccagc
    32821 cgcaaccaaa ccagcgatat gggccatgtc caccatgagc ttcgcaccga cagcatctgc
    32881 gatttcacgg aattttgaaa aatcgataat ttgagaatat gctgaagcac cagctacaat
    32941 cagttttggt tttacttctt gggcttgttt caagatagca tcaaagtcta agagttctgt
    33001 ttcaggatcc acactataag aaacaaagtt gtaggtttga ccagagaagc taacaggagc
    33061 cccatgagtc aaatgaccac ctgatgccaa atccattccc ataaccgtat cacctggctc
    33121 aatcaaggac atgtaagccg cacagttagc ttggcttcct gaatgtggtt ggacattggc
    33181 aaatttagca ccgaaaattt cttttgcgcg ttcaatagca agagtctcta caacgtctac
    33241 tacatcagtt ccaccataat aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa
    33301 gatagaccct tgagctgcca taacagcctt ggaaactacg ttttccgaag caattaactc
    33361 gatattattt tgttggcgtt cttcttcttt ggcaatagca ttccagagat cagcatcata
    33421 tgctttaaaa tcatctttgt caaaaatcat aggtcttctc ctttattgtg tgactagtcc
    33481 attagtttga ttttacaata agaaaatcaa actaacagat gcgaataaac cgtttctgca
    33541 ttttatcaca agtatagcca actttttcat aaaatgcatg agcacccaga cgatgattgg
    33601 cagaatttaa gcggataaac ccataaccac atctttttgc ttcttcttcc aacccttgta
    33661 gtaaactttt accaatacct tgaccttgcg cttgaggtga aactgctaaa gctaagatat
    33721 taaatcctgc tttggaatag agtgattcgt aaacttcagc gtggacatat ccaagtaaga
    33781 catgattagc tgcatcctca tagccaagta ggaaatgatg ggaatcctga gacagtctag
    33841 ctagttggct agccgtttcc tctggactaa aagtataacc caaagcctct tggttgatgt
    33901 cacatatcgc tttcacatct gtttcttgca aatctcttag catttcaagc ctcctcaaaa
    33961 gaaatctctg gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt
    34021 ttcaccttgt ctccagacaa atccacaata gttgaatcct gtccagttag aaaagcatcg
    34081 tcttccagac ccagaacctc ttggtcaaaa tccttcagaa tttgttcaaa ggttacacca
    34141 cttgcctgac ctgagatatt ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa
    34201 tccagtgtga tagggtgact gggcatccga aatccaatag ttgcaaggtc agaatttacc
    34261 caatagggaa ctcggtcatt ggcttcgaga ataatggtca agggacctgg caaaaaggtc
    34321 tctacaagtt tttgtagata agctggctga ttcttagaaa agtgcaagat gtcctcgaaa
    34381 gaggcgatat tgagattgag tgccttatct ctaggacgac gtttgagttg gtaaacatgg
    34441 tcgacagctt tttcatctaa ggccttagca aaaagaccgt aaaccgtctc tgtaggtaga
    34501 acgacagctc caccattttc caactcttgt ctaatcctgt ccatcatcaa ccacaaccat
    34561 cctgttttga ccaaattggt ccttgagtgt tcgaactctt ttttcaggaa gatgtttcct
    34621 aaaaagttcg ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc
    34681 atctttgaga tagtcttttg catcttccgc aattctacag taaatagcta ggccatcctc
    34741 gtctgcaaag agagctagat gaggctccga atgcaaaaca ttcaagccta cctctgactc
    34801 atcttcacga gagatatagg gtggattgga tacaattata tcatattttt cagaaatttc
    34861 tgcaaaacaa tcagattttt taaaaaatat attaagattt tgattgctag cattctctga
    34921 tgcaagctct aaggcctctt gagaaacatc tgctgctgtc actgaccaag ctggtctatt
    34981 ttttgctaga gcgagagcaa tagctccact acctgttcca atatccagaa ctgagagatt
    35041 cgtctcaaga ttttcagtta gaataagctc cactaactcc tctgtttctg gacgaggaat
    35101 caaaacccgt tcatccacct ttaaatgcat tccataaaaa tctgcctgtc caatgatgta
    35161 ctgagctggc ttgtgagctg ctagttgctg gtaaatatct tctacaaatt gtttttcttc
    35221 ctctgttgtc acctcctgct ggagggcaaa aataaagtct gtaaaagata gatttttcag
    35281 actacgatag acaaaagaga ggctttccgc ttcctctcct tgtcttatca actcttcttc
    35341 aaaatttgaa aataattgag ctaatttcat tatttgttta attcttctag tttttgtgtt
    35401 tggtcataaa gcaccaaggc atccacaact tcgtccaatt taccagacaa aatcgtatct
    35461 agtttttgga gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg gaagttataa
    35521 gttcggatcc gttctgaacg gtcaccagta ccgattgtcg acttacgctc agcgtcctgc
    35581 tcatcttgag caatctgagc aaagtggtca gcaacacggg cacggatgat tttcatggcc
    35641 ttctcacggt ttttctgctg ggtacgttct tcttgcatct caaccttgat attggttggc
    35701 aagtgaacga tacgcacggc agtcgcaacc ttattgacgt tctgaccacc agcacctgat
    35761 gcgtggtaaa tatcaacacg aagatctttt ggatcgatat cgtattctac ttcttcgact
    35821 tcaggcatga caagaactgt ggcagttgag gtatgaacac gaccttggct ttctgtcacg
    35881 gggacacgct gcacacggtg ggcacctgat tcatacttaa gcttagagta tacagactga
    35941 cctgaaacca tagcaaccac ttctttaaaa ccaccgacac cattcataga ggcttccatg
    36001 acttcaaagc gccaaccttg ggcttccgca tacttttggt acatagttag caaatctcca
    36061 gcgaaaagtg ccgcttcgtc tccaccagct gctccacgga tttcaaggat gatattcttg
    36121 tcatcgtttg gatcctttgg aaggagcaaa attttcagtt tttcttcata ttcttctttt
    36181 tcagccttgg catctttgag ttcttgcttg gccaattctt ccaagtccgc atctccgcct
    36241 gattccttaa tcatctcttc ggcatcgacg atattttgaa ggacttgttt atactcacgg
    36301 taggctatta cggtgtcacg attggaagct tcttcttttg aaagctccat aaaacgcttg
    36361 gtgtctgaaa cgacatcagg gtcactcagc aattctccta gttcttcata acggtcttct
    36421 acagcttgta gttgatcata gatgttcatt tttcttcatt ctccttattg atttcagggg
    36481 caaaataatg tttacggcaa accgagatat aggtttcatt accaccaatc tggatctgtt
    36541 ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac catggtcgcc tttttcttgc
    36601 aatactgaca gatggtcttg atttcgtcaa tcttgtctgc taaaagcaag agatatttgg
    36661 aaccttcgaa caattcattg cgaaagtcat ttttcaagcc aaaagccatg acgggtatgt
    36721 ctaactcgtc cacaacacga gctaggtcat aaacatggtg gcgtttgaga aactgggctt
    36781 catcgaccaa aacacagtaa ggtttttctg gtaggtctcg gatatagcca aagatatccg
    36841 ttgtttcctc aatagcaagg gcagggcgtt tcatgccaat tcgactcgac acatagccaa
    36901 caccgtcacg cgtatccaga gccgaggtca taatcacaac accttttcct tgctcctcgt
    36961 agttataggc cactttgaga atctcaatcg ttttaccaga gttcatggtc ccataacgat
    37021 agtacaactg tgccatgttt cttgcttcac gtccatttct aaatttttgc tacattctag
    37081 tatatcataa ttttcttaag ctttaaacgg caaaatgtgg taaaatggaa gaaatcaaaa
    37141 ctagtggagg aagctattat gccatttgta cgcatcgatt tatttgaagg acgcacgctc
    37201 gagcaaaaga aagctcttgc taaggaagta acggaagcag ttgtccgcaa cactggagca
    37261 cctcaatctg ctgtccatgt catcatcaac gacatgccag aaggaactta cttcccacaa
    37321 ggggaaatgc gtactaaata agctagctta agcagaattg cttaggcttt ttcaatctcc
    37381 aagtagcacc cattgaagaa atagtctaaa tttgttacaa tttgaaaaga gacttggaaa
    37441 attccaagaa aagagcaatt aattaaagga aacattatga ttacacgtga atttgatacc
    37501 atcgctgcta tctctactcc actaggtgaa ggagctattg gtattgtccg cctgagcgga
    37561 acagacagtt ttgctattgc gcaaaagatt tttaaaggaa aagacttgag tcaggttgct
    37621 agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag
    37681 gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt
    37741 aacacccacg gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga
    37801 gctcggttgg cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat
    37861 ttgacacagg ccgaggcggt gatggatatc atccgagcca agacagacaa ggccatgaac
    37921 atcgcggtca aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa
    37981 atccttaaca cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt
    38041 gaggaagcca ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc
    38101 aaactcctta ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc
    38161 attggacgtc ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag
    38221 gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc
    38281 aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga tgacatagtg
    38341 gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt ggttctacta
    38401 gtgctaaatg ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa
    38461 gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg
    38521 aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt
    38581 gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca agatgctact
    38641 tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc
    38701 gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt
    38761 acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa
    38821 ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg
    38881 gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg
    38941 cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg
    39001 gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa
    39061 ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa
    39121 ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat
    39181 ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga
    39241 aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt
    39301 aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca
    39361 agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa
    39421 taattggtag gtcagaagca tctgcaatag ccttaaagtg ctgatacatc ccttcttgag
    39481 aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta
    39541 cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag
    39601 gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg
    39661 tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca
    39721 ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc tcatggaagg
    39781 gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac acgaaaacac
    39841 ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca
    39901 aatttcaatt cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga
    39961 actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct
    40021 ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca
    40081 ttgatagctt gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag
    40141 gctgcgatag ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca
    40201 gactcagagt gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta
    40261 tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca
    40321 ttatcagtga aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg
    40381 tcaccacctg aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag
    40441 acttcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct
    40501 tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc
    40561 accatcattt ggattgttga acaattaggg caggcaatga ttccgttgtg agcatcaagt
    40621 gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat
    40681 gtattatcta ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta
    40741 gaactacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct
    40801 tcaattgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca
    40861 aggtaacgga ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca
    40921 ccgacggcac ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg
    40981 aattttctaa aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc
    41041 tttttcatca ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat
    41101 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    41161 ttatgctcaa tagtagtccg aagactacct atcgactcat cgcatattct atattactag
    41221 agatacttga ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aaactctcgt
    41281 attcaagagt ttccctatac atatcatgct aattgccggg attgaaccgg cgacctcatc
    41341 cttaccatgg atgcgctctg ccaactgagc taaatcagct tacttaagaa gtatactata
    41401 ttcagaaaaa cttgtcaagt ttccttagaa attttccata ggaaaaagcc aggtaagaac
    41461 tacctagctt atcttcttct atttacttaa atcaattcga cgaccaattt taccaataat
    41521 aatcgctcca ataatcaatg aagcaaattc accgattcct gttgtaaacc aagtaaggaa
    41581 gaatggtaat tctgctacaa tatttaactc tgcagcgata gtaaacatgg aaattgaaaa
    41641 gaggattgaa aagaagaaat gatcttttcg aatcaatccg ttaaagaggt aatccttgct
    41701 atattttgca aaaagccaaa cacctaaact gaggaatact aaggttgaac caccaccaac
    41761 aaagacatct agcagtccga agctaaagaa attagcaatc atacaaccga tggtaactcc
    41821 gatgatgtac ttaggattgt aaaaagccat aaagttcatc atttctgaaa tacgaaactg
    41881 ataagcacca tagctgatgg catttagggg cggtgtgaca gtcaaaacga cgtagatagc
    41941 agcgacgatt gcaatatctg caacatcacg aatagttaat tttttcatct tttctccttt
    42001 ggcggttgcc cgcgtgtaat atgcttggtg aaagaagcta agcaccaagg gttgctttat
    42061 tcaaccctac tagtatagca caatagcctg ctttatgcta tacttaacac atgaaaattc
    42121 ctattcaaaa attttttaac aatgaaatct tagcctatct cttttttggt atagtgacta
    42181 ctcttgttgc tatactatta cgattagtca tttatcagct aagtcatcaa gaactccttg
    42241 ctacggcctt ggcaaatatt atcggtattt tatttgcctt tatcacaaat gatacaattg
    42301 tatttaagca aaaaaagaaa aatagactta tccgtttagt gaaattttct cttgctcgcc
    42361 tttctacttt tctgttagac ttgtttttaa cttttctctt tgtaacccaa tttcctcaca
    42421 tcatagggca attcgtaact gaaaacattg ataagataaa tgctattgaa acaataattg
    42481 cacaaatatt cattattatc atcaattata tcttgagcaa ggtctatatt tttagaaaat
    42541 aatgctccat ttatgagcct tttaattgcc ttctataatg atttaggata caatgaaaca
    42601 cgaaacattg aaaggaaaac agtatgttaa aaaatctaaa atcgttcttg cttcgaggaa
    42661 atgttattga ccttgctgtc ggtgttgtaa ttgcctctgc ttttggtgct atcgttactt
    42721 cacttgtaaa cgacattatc actcctctta ttttaaatcc cgctttgaaa gctgctaaag
    42781 ttgaacgtat cgctcaactt tcttggcatg gagtcggcta tggtaacttc ttaagtgcta
    42841 ttatcaattt tatctttgtg ggtaccgccc tcttctttat tatcaagggc attgaaaaag
    42901 cacagaaact gactggcata aaggaagaaa aaactgccga aaaaaaacca accgaattgg
    42961 aagtccttca agaaataaaa gctctccttg agaaaaaata atcgattaaa aggatctagc
    43021 gcaaagctaa atcctttttt ctttactctt tgggtaactt gcctgctttt tcaagcattt
    43081 ttttgataag ataaggcatc ttaacattct cccgcccttt tttctcaatc agttttttca
    43141 caaattctgg catttgtaaa tcttgagatt cggctaagat atttttagtc tcatctgaag
    43201 gcactaactc atcaaaggtt tcttcttctg ggagaaattc cttaaactct tgattttcat
    43261 tgactctaac tgtattgacc aaggcatcaa tcaaacgaga atctgtattt ggcattggtg
    43321 gacgatggta gtttacccca aattcctgac ataaatcata acattccaca tcattgtcaa
    43381 acaagacctc aatatgctca ctgatgaaac taataggtac aaaaatataa tggtctggat
    43441 gttctgtctg ttctctgaga tactccaaaa catctggttt aatccatgga ataccaatat
    43501 cactctcact ctgccaagtg ttggtatatt gttctgaact caagcccagt ttttcagcga
    43561 ctagcttgct attttcgaaa atttggtcta tataaggatc tccaaagtcc aaggcaaaaa
    43621 taggcacact atgggctgaa aagatgactt taaagctgtc ttgctttact tcttctttta
    43681 aaatcttagc aatttcatct gcccaatagt ttaagagcgc ttcttcctga taccagtcct
    43741 taatgaccaa aaattgaatt tgtttgcttt ctaaaaattt ttcatagccc atgacagagt
    43801 agaaagaata atggggctcc aaaatcaagc aaatacactg ttcaattccg tctgcttcca
    43861 tttgaccgat cacatctgga ataaagggac tggaaaactt attagcaaag tagacactgt
    43921 attcattccc cagcctagct tctaccaagg caacctcttg acgggtaatt ttttgcagag
    43981 gcgtgcctcc aattcgtaca taattatcat agagagtctg aatctcgtgg tcttggggtc
    44041 tcatcccacg acgaatattt gtgaaaaaat cagctacacc ttcaaaggta atctcttctg
    44101 gtgaaccgaa ggtcatcatt aaaattgctt ttttcatgac tgcttccttg tgatgttttt
    44161 atcaagttta ttttatcatt aattcatcga taagtaaacg ctagcatagg gacattctca
    44221 atcttctgtc ttttgttttt ctcttctttc tatgatacaa tggaaaaaat aaattcaaaa
    44281 ggagtttttt tatgacttat ccaaatctct tggaccactt cttaacctac gttaaggtca
    44341 acacgcgctc tgatgaacac tctactacta ctccaagtac acagagtcag gttgacttcg
    44401 caacaaatgt cctaattcct gaaatgaaac gtgttggact gcaaaatgtt tactatctac
    44461 cgaatggttt tgctattgga accttgccag ccaacgatcc gtctttaaca cgtaagattg
    44521 gttttatatc gcacatggat actgctgatt ttaatgctga aggagtcaat ccacaggtaa
    44581 ttgaaaacta cgatggtggt gtgattgaac tagggaattc tggtttcaaa ctcgatccag
    44641 ctgacttcaa gagtcttgaa aaatatccag gacaaacgct catcacaaca gatggaacaa
    44701 ccttgctagg tgctgatgac aagtcaggaa ttgctgaaat tatgacagcc attgaatatc
    44761 taactgctca tcctgaaatt aagcactgtg agattcgtgt tggttttggt ccagatgaag
    44821 aaatcggtgt tggtgccaat aaatttgatg cagaagattt tgatgtggat tttgcctaca
    44881 ctgttgacgg tggtccacta ggtgaacttc agtacgagac tttctcagcc gctggtgctg
    44941 aattgcattt ccaaggccgt aatgtccacc ctggtactgc caaagggcag atggtcaatg
    45001 cccttcagct agcaattgat tttcataatc aacttccaga aaatgaccga cctgagttaa
    45061 ctgaaggtta ccaaggtttt taccatctaa tggatgtgac aggtagtgtt gaggaggtgc
    45121 gtgcaagcta catcattcgt gattttgaaa aagatgcctt tgaagcgcgt aaagcatcca
    45181 tgcaatctat cgctgataag atgaatgaag aacttgggag cgaccgtgtc actctcaact
    45241 tgacagacca gtactacaat atgaaagaag tcattgaaaa agatatgact ccaattacca
    45301 ttgctaaagc cgttatggaa gatctaggta tcacgcctat tatcgaacca atccggggtg
    45361 gaacagacgg ctctaagatt tcctttatgg gaatcccaac tccgaatatc tttgcaggtg
    45421 gcgaaaatat gcacggacgt tttgaatacg ttagccttca gactatggaa cgtgcagttg
    45481 ataccatcat tggcatcgta gcttataaag gctaaaaaga cgaggtagct cagctacttc
    45541 gcctttcttt ttattctact ggtttttctt gatttccagt agttgtagaa gattctgttg
    45601 tttcattttc tgaagttgat tcagcaggtt tagaatctct tgtattgctt ggtttgtttt
    45661 cgtcgctagc agtttcaatg ttagattctg cagttgcgtt tggttggttc tcagcactgg
    45721 tgttatcact atttgcttca gcatttcttg ctggacttgt ttcttcactt gcgctagctt
    45781 ttgactggat ttgatgattc aaaactagaa tagcttttgt cgattcaagt aaagctgttt
    45841 tgtctttact cttagcagaa agttgatcta ataatgcatc caccttatca aagtccgcat
    45901 cagatccatt attactttct aaataagagt gaagcgacat gagaatatcg tagagttttt
    45961 gatagagtac aagtgtctga gaatcttgct cagcattttc cttttcttgt tgaagggcgc
    46021 tagcgatacg agtcaaaaca tcttttacct gactgtttac ttcatccaag tctgcatcag
    46081 ccttgtttgt ggcagctttt agattttcta cttcttctgc caaggattgt ctgattcctt
    46141 cttcatggat ttgttccaag agttgatttg ccttgttcaa aaaactttct acttcttcct
    46201 tgctatctgt cgcagattat tggttgctat ctaccatgta ctcctaaaac aggagagtta
    46261 taatccaaga ttacaaggcc ttacagaaat aagaaatcca gataagacaa tgttcgtcca
    46321 agacgctatt cgcttcgcac agcagcacgg attcaatata ctttaatttt aaagtttagg
    46381 tgtcaagacc tctttttagt gtgcccaaaa tttagagaag taatcaatca actaactttt
    46441 atttttttca aactttcagt aaactgacct aaagctaact caatctgtct ttgttcgata
    46501 ggcttgtctt tgtagatgct tctgctatca gctagaagtt gatctacttt tgccaagact
    46561 gccttctcat caaaagttcc aggttgatag ttggattgca gggatggaat cttgtttttc
    46621 aaagccgctt catatccctt agtttgaacc ttgatgtagt gattgtggtc gccacgagga
    46681 atcacaaaac cttctgaatc ttcacttata attcgattgg catcaaaacc atgaccatct
    46741 tcttcctcat ggtggacatg tagtgacgga ttacttaata cagaactaga agaacttcct
    46801 accttttccg tgttagagtg tgatggggga ttgttaagag atgacttagg aatatagtga
    46861 tagtgacccc atgtcttact atataagcat cacctgtatc tctgacaata tcattagggt
    46921 taaagacata accatcatct gctgcagaaa caccattatt cggtgtcacc gacaaagatt
    46981 gactgagagc tgtagtattc tctgataatt atacttttgc agctgctaat tcacctgccg
    47041 acaagtcact ctcaggaatg aaatgatagt gaccaccatg tggtactata gtagattgaa
    47101 atagaatatg agcaaattga taaggggatt ttaaagtaat ttctaacaat gatttagaaa
    47161 ctatgatgtg ctattctaaa ttcaactcac tatatataac catcatcggt agtataacgt
    47221 ccctgtaatt ttgctacaga tacttctgca ctagctcctt tatcgtcttt accatgttct
    47281 tgtttttggc gattgatttc atcttttatt cgtacatttt ctgcatgagc ttgatcttta
    47341 aggtaaacat aatactttcc atctacctta ataatatatc ctcccttaac ctaactgacg
    47401 atatcttgat ctttcggctg atagttgggg gctttcatta atagctcttc actaaagagc
    47461 gcatacaaag gaactttacc attatagcag tgataatgat cgccatgaga agttacataa
    47521 ccttgatctg taatcttaat aacaatttgt tttgcttgaa ttccttcttt ttgactaacc
    47581 tagtctggag tcaaattttc agtcttctta gtgtctttat tactgtttac atatgaaaca
    47641 cgatttttat ctgtattggc ctgttagcta tgttggttca gagcataaac acacagactt
    47701 aaggaaagga taacaacaga tccagctgtt atatatttct ttttaaattt cataattacc
    47761 tcatttctat aattatttat atgatgtctt cattattaaa tgattaaata aattaattaa
    47821 ccaattaatt aactagtaaa tattccacct ctttttaagt tgtatgtcaa gaaattttat
    47881 atattaataa taaaatgaaa ttctcccaaa gtcagagttt tatttctaac ttttgagaga
    47941 acttcatttt tgattcagac tttttctact gctattcctt acgctatgag atcagataaa
    48001 ttctttttta tcacttctcc acttggcaat cttaattcaa tcgttccatc catattgaat
    48061 ataacactat ctaaacctaa tccataacta gctgtaaatt tttctaattt ttcttgtaca
    48121 ggatctactg ctggagcttc ctctaatgct ggatctaaca tagggtcact ccccacattc
    48181 ccttctggat tcaacattcc attatccgtt gagttttctg gttttacagg ttttttgttt
    48241 ggtgcctctg gtaaagaatc tgctggttta ttttctgttg gttggttctc aactgttcca
    48301 gtagatactt ttccattttc agatggttta ttttcaccat ttccttgagg tgcttctcct
    48361 gtaaaatctg ccatattctt tttaatgact tctcccgatg gtaaatataa ttcaattgtt
    48421 ccgtccatat taaacaagac attttctagc ttcatcccat aactttcagc aaattttgct
    48481 actttttctt gtacaggatc cactgtagga acttcttcta acgttgaatt actagtacta
    48541 ttcccagttt cagaaagttt ttctttttct accttctcac tagtctttgg ttcttctacc
    48601 ttttcatcaa gttttgagtt ttcttgtgct ttattccttt taaattgtgg tagaatactt
    48661 ggtttatcag tttgattttc tttttccaag ataggtactt ccacaatata agtcgattga
    48721 ttgtccaaat aagcatttgc catgaaggtt acaggaattt tatttccggc cgttctggtt
    48781 gttccttggt ttaatttcgg aatcggtaat ttaatttcac caactttata gttattttct
    48841 aaataagcat ttccatgaaa ttcatcaaac actctgacta aagcatcagt tcctttaggc
    48901 actgcaaatt gagggttcac tcttaaataa gtatcccctg catggaaagg atagaaaatc
    48961 gtttgactgg ccattttgta agctaaagag gttggaactg taaatgtacc atcataactt
    49021 acttctggat aatcttttga agcgatagta tacttaaatg tttgtcctgg taaataaggt
    49081 tgatctaatt caaagtttgc aatattccct actccttctc caaatacttt accagatact
    49141 ttctccaata cttttccatc tggtgttatt aattttacta gcatattgat acctaatttt
    49201 ttctccaatt caggcggaaa actaaaagaa acgcgttttt gaccattggc tagagtaaag
    49261 ttttgattat taaacgtact attttttaac aaattaacaa cattcgttaa ttcttctcca
    49321 gtataaactt tattcccttc ttttttagca actccttctt cgggtttaaa cagttcatag
    49381 ttactgtgag aatgaccaat tccaaccggt ttatgttcat caatcggatc tgcatgatgg
    49441 tgatctccat gcggataaat aatcgcattt ttttctttat tcacgacaat actttcacgt
    49501 ttgacaccat attgtttcat aatgccagca attttttctt cgattttttt atctaaatct
    49561 ttcatttctt tggcattact tggataatcc tgttcatgag atgacaaaga atctaatcca
    49621 ttatgactag ttttaacttc ctctaaatgt ttttgcgcag ccttaatttg ctcttctgtc
    49681 aagtccttct tgaagaaata atgattgtgg tctccgtgac tcatgacaaa acctgattca
    49741 tcttcagcga taatacgatt agcatcaaat ccgtatccat cttcttcatg tttctcatgt
    49801 gaagttcctg gattgattgg aagagatgga gaaggtgttg ctagactatt gtttggaaga
    49861 gtcggttgcc caatttgatt tgattttgga atgtaatgga aatgatcacc atgtcttaca
    49921 atataagctg tagccgtttc ttcaacgata tcttttggat taaaaatata accatcagat
    49981 gctgaagaga gctccttact tgtcgttaaa gaagaaggat tgcttgaaag actgcctaga
    50041 ctagacacta cttcattagg ttttgcattt gtagaaactg tagaaccagt tccactgata
    50101 ggcaccattc tggcaatctt ttcttctaag gcagaaagct tgctgtaagg aataaagtgg
    50161 taatggtcgc catgcggaat cgcaactcca tttggtgtac gactgataat cttagcaggg
    50221 tcaaagacca ggccatctga ttcactgtaa cgttgggcgc taggtgaatc atagagttcc
    50281 ttcaaaagac tctggagatt ttcagattta tttgctggct tgctagttga tccttttgct
    50341 acagattgcg tgttattgtc actagctgtt gaagaatagc ttaactgact cggttgcata
    50401 ttttttccag ccagatgtgc tttagctgct gctaattcac tagcagataa atcgcttttg
    50461 ggaatgtagt gatagtgacc tccatgagga acgatataag cattacccgt atcttcgata
    50521 atatcagctg gattaaagac ataaccatca tttgtcgtat atcgtccctg agaccttgct
    50581 acagcaacat tagagttaac cttctcatta tctttgacat gttcttgttt ttgacgattg
    50641 atttcatctt tagttcgaac attatcagca tgagctgcat ctttcaggta gacataatat
    50701 tttccatcga ccttgatgat ataaccaccc ttgacttcat tgacaatatc agcgtcttta
    50761 agttgatagt ttggatcctt catcaagagt tcttcactaa agagggcatc ataaggaact
    50821 ttcccattat agtaatgata gtggtcaccg tgtgacgtta catagccctg atctgtaatt
    50881 ttgattacaa tttgctcagc ctgaattcct tctttctggc taacctggtc tggtgtcaag
    50941 ttttcacttt tctgacttga ctggctgcca tccacataag agacacgatt attgtcctta
    51001 ttttcctgcg aacgatgctg gtttagtgca taggcacata gactcaagga tacgataaca
    51061 gctgatccag ctgctatata ttttttacta aatttcataa atccctcatt tcaataaatg
    51121 atgaagtttt ttctcaactt cttttacttt attaaatagt tttctaaacc ggttatttaa
    51181 ccatttaatt aaccagtaaa tagtttacta tttaaaatta cttttgtcaa gtttctgtta
    51241 cgtttttcta aaaaagagaa gtaacacgaa aggttacttc tccataaaat atgctccatt
    51301 cattttacta ctgtatcgga gccggttgac ttttttttaa caaagccaag agactatcta
    51361 cttctgctga aatagtgtta ttatctttcg ttccgagaag aagactactt tttagaccag
    51421 tcaatgtctc catagcattt tgtctaatac tagaatctgt tactttttct agcaaggcct
    51481 ccgc
//
LOCUS       DBEJNA010000012        49791 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEJNA010000012 DBEJNA010000000
VERSION     DBEJNA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.12"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            144..1163
                     /gene="galE"
                     /locus_tag="ACL3JB_000792"
     CDS             144..1163
                     /gene="galE"
                     /locus_tag="ACL3JB_000792"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0685559.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            1165..2118
                     /locus_tag="ACL3JB_000793"
     CDS             1165..2118
                     /locus_tag="ACL3JB_000793"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0685560.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(2180..2386)
                     /locus_tag="ACL3JB_000794"
     CDS             complement(2180..2386)
                     /locus_tag="ACL3JB_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0685561.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            2438..2914
                     /locus_tag="ACL3JB_000795"
     CDS             2438..2914
                     /locus_tag="ACL3JB_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0685562.1"
                     /translation="MAKEPWQEDIYDQEESRAGHRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            2923..3594
                     /gene="cmk"
                     /locus_tag="ACL3JB_000796"
     CDS             2923..3594
                     /gene="cmk"
                     /locus_tag="ACL3JB_000796"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0685563.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            3725..4063
                     /locus_tag="ACL3JB_000797"
     CDS             3725..4063
                     /locus_tag="ACL3JB_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0685564.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            4066..4695
                     /locus_tag="ACL3JB_000798"
     CDS             4066..4695
                     /locus_tag="ACL3JB_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0685565.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            4935..6086
                     /locus_tag="ACL3JB_000799"
     CDS             4935..6086
                     /locus_tag="ACL3JB_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0685566.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            6399..7148
                     /gene="truA"
                     /locus_tag="ACL3JB_000800"
     CDS             6399..7148
                     /gene="truA"
                     /locus_tag="ACL3JB_000800"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0685567.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTN
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            7138..7911
                     /locus_tag="ACL3JB_000801"
     CDS             7138..7911
                     /locus_tag="ACL3JB_000801"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0685568.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            7889..8350
                     /locus_tag="ACL3JB_000802"
     CDS             7889..8350
                     /locus_tag="ACL3JB_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0685569.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(8609..8857)
                     /locus_tag="ACL3JB_000803"
     CDS             complement(8609..8857)
                     /locus_tag="ACL3JB_000803"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685570.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(8805..9887)
                     /locus_tag="ACL3JB_000804"
     CDS             complement(8805..9887)
                     /locus_tag="ACL3JB_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0685571.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(10013..10795)
                     /gene="gatD"
                     /locus_tag="ACL3JB_000805"
     CDS             complement(10013..10795)
                     /gene="gatD"
                     /locus_tag="ACL3JB_000805"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0685572.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(10795..12138)
                     /gene="murT"
                     /locus_tag="ACL3JB_000806"
     CDS             complement(10795..12138)
                     /gene="murT"
                     /locus_tag="ACL3JB_000806"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0685573.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(12237..13553)
                     /locus_tag="ACL3JB_000807"
     CDS             complement(12237..13553)
                     /locus_tag="ACL3JB_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0685574.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGTFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            13747..14973
                     /locus_tag="ACL3JB_000808"
     CDS             13747..14973
                     /locus_tag="ACL3JB_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0685575.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILAGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            15172..16746
                     /locus_tag="ACL3JB_000809"
     CDS             15172..16746
                     /locus_tag="ACL3JB_000809"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0685576.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            17010..17798
                     /gene="codY"
                     /locus_tag="ACL3JB_000810"
     CDS             17010..17798
                     /gene="codY"
                     /locus_tag="ACL3JB_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0685577.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            17798..18373
                     /locus_tag="ACL3JB_000811"
     CDS             17798..18373
                     /locus_tag="ACL3JB_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0685578.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            18455..18540
                     /locus_tag="ACL3JB_000812"
     tRNA            18455..18540
                     /locus_tag="ACL3JB_000812"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18489..18491,aa:Leu,seq:aag)
     gene            18823..19953
                     /locus_tag="ACL3JB_000813"
     CDS             18823..19953
                     /locus_tag="ACL3JB_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685579.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            20454..21212
                     /locus_tag="ACL3JB_000814"
     CDS             20454..21212
                     /locus_tag="ACL3JB_000814"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0685580.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            21300..21812
                     /locus_tag="ACL3JB_000815"
     CDS             21300..21812
                     /locus_tag="ACL3JB_000815"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0685581.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            21994..22938
                     /gene="metA"
                     /locus_tag="ACL3JB_000816"
     CDS             21994..22938
                     /gene="metA"
                     /locus_tag="ACL3JB_000816"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0685582.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            22947..23624
                     /locus_tag="ACL3JB_000817"
     CDS             22947..23624
                     /locus_tag="ACL3JB_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0685583.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTSQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            23722..24480
                     /gene="tpiA"
                     /locus_tag="ACL3JB_000818"
     CDS             23722..24480
                     /gene="tpiA"
                     /locus_tag="ACL3JB_000818"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0685584.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            24518..26023
                     /gene="lytC"
                     /locus_tag="ACL3JB_000819"
     CDS             24518..26023
                     /gene="lytC"
                     /locus_tag="ACL3JB_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0685585.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDFN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            26520..27038
                     /locus_tag="ACL3JB_000820"
     CDS             26520..27038
                     /locus_tag="ACL3JB_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0685586.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            27168..27674
                     /locus_tag="ACL3JB_000821"
     CDS             27168..27674
                     /locus_tag="ACL3JB_000821"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0685587.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            27876..29108
                     /gene="clpX"
                     /locus_tag="ACL3JB_000822"
     CDS             27876..29108
                     /gene="clpX"
                     /locus_tag="ACL3JB_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0685588.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            29117..29704
                     /gene="yihA"
                     /locus_tag="ACL3JB_000823"
     CDS             29117..29704
                     /gene="yihA"
                     /locus_tag="ACL3JB_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0685589.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            29715..30095
                     /locus_tag="ACL3JB_000824"
     CDS             29715..30095
                     /locus_tag="ACL3JB_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0685590.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            30147..31037
                     /gene="rapZ"
                     /locus_tag="ACL3JB_000825"
     CDS             30147..31037
                     /gene="rapZ"
                     /locus_tag="ACL3JB_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0685591.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            31034..32011
                     /locus_tag="ACL3JB_000826"
     CDS             31034..32011
                     /locus_tag="ACL3JB_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0685592.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            32008..32919
                     /gene="whiA"
                     /locus_tag="ACL3JB_000827"
     CDS             32008..32919
                     /gene="whiA"
                     /locus_tag="ACL3JB_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0685593.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(32953..33921)
                     /locus_tag="ACL3JB_000828"
     CDS             complement(32953..33921)
                     /locus_tag="ACL3JB_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0685594.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIYPEQKVQPKHSTSL"
     gene            34057..34914
                     /gene="cdaA"
                     /locus_tag="ACL3JB_000829"
     CDS             34057..34914
                     /gene="cdaA"
                     /locus_tag="ACL3JB_000829"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0685595.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            34901..35680
                     /locus_tag="ACL3JB_000830"
     CDS             34901..35680
                     /locus_tag="ACL3JB_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0685596.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            35704..37056
                     /gene="glmM"
                     /locus_tag="ACL3JB_000831"
     CDS             35704..37056
                     /gene="glmM"
                     /locus_tag="ACL3JB_000831"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0685597.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            37130..37504
                     /locus_tag="ACL3JB_000832"
     CDS             37130..37504
                     /locus_tag="ACL3JB_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0685598.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            37506..38354
                     /locus_tag="ACL3JB_000833"
     CDS             37506..38354
                     /locus_tag="ACL3JB_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0685599.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            38620..39387
                     /gene="dapB"
                     /locus_tag="ACL3JB_000834"
     CDS             38620..39387
                     /gene="dapB"
                     /locus_tag="ACL3JB_000834"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0685600.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            39384..40583
                     /locus_tag="ACL3JB_000835"
     CDS             39384..40583
                     /locus_tag="ACL3JB_000835"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0685601.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAI
                     TEKYQSLTIHDKKDIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            40580..42451
                     /locus_tag="ACL3JB_000836"
     CDS             40580..42451
                     /locus_tag="ACL3JB_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0685602.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYRGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIEALEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(42594..43778)
                     /gene="mntE"
                     /locus_tag="ACL3JB_000837"
     CDS             complement(42594..43778)
                     /gene="mntE"
                     /locus_tag="ACL3JB_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0685603.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            44082..46778
                     /locus_tag="ACL3JB_000838"
     CDS             44082..46778
                     /locus_tag="ACL3JB_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0685604.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDITPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            46791..47582
                     /gene="yghU"
                     /locus_tag="ACL3JB_000839"
     CDS             46791..47582
                     /gene="yghU"
                     /locus_tag="ACL3JB_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0685605.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            47698..48108
                     /locus_tag="ACL3JB_000840"
     CDS             47698..48108
                     /locus_tag="ACL3JB_000840"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0685606.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            48120..49715
                     /locus_tag="ACL3JB_000841"
     CDS             48120..49715
                     /locus_tag="ACL3JB_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685607.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVNDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT        14470 a         9338 c        11369 g        14614 t
ORIGIN      
        1 cgacgttgac gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta
       61 tcaggtagtt taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat
      121 aatctgagaa tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt
      181 ttattggaac ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg
      241 ataatcttgt caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg
      301 agattccttt ctatgaggca gatattcgtg acacagctac cctcagagat attttcaagc
      361 aggaagaacc gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac
      421 gtatccctct tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca
      481 tggaagaaaa caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggggatc
      541 cgcacacagt gcccatcttg gaagatttcc cactttcagt gaccaaccca tacggtcgta
      601 ctaagctcat gctagaggaa attttgactg atatttacaa agcagactca gaatggaatg
      661 ttgtcttgct tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa
      721 atccaaacgg tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat
      781 tagagcaagt gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg
      841 actatatcca cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa
      901 aaggttcagg actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa
      961 ttatccaaaa catggaaaaa gcggtgggac gtcctattcc ttaccgcatc gtagaacgtc
     1021 gcccaggtga tatcgctgcc tgctactcag acccagcaaa agctaaagca gaactcggtt
     1081 gggaagcaga actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc
     1141 atccaaatgg atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa
     1201 gaggaagtac ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca
     1261 gaaatcgagt atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag
     1321 gcctatcggg agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa
     1381 gaagcagccc tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat
     1441 gcagacctcc aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat
     1501 gtagacttgg actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc
     1561 agtttctgtg ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg
     1621 tcgggtgtcc gtgattttcg tatgatgaga aggtctgtag tcgatgccat tttaagcttg
     1681 accgagtcca atcgtttttc aaaggggctc ttcgcctggg tgggtttcaa aacctactat
     1741 ttggactatc caaatgtcga aaggcaggct ggcaagacca gttggagttt taggcaactc
     1801 tttttttact ccattgaagg gattgttaat ttttcagatt tccctttgac tatagccttt
     1861 gtagctggtc tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg
     1921 accctcattt tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt
     1981 cttggaggca ttcaactctt gaccattggg attctcggta agtatatcag taagatttat
     2041 ttagagacta aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt
     2101 acagaaaaaa taaagtgaaa agactataat tttacatgga aatgtgctaa actagaggga
     2161 gtggattatc gccattgatt taggcttcct ggtttccaat cagggcgcga gttgggcaat
     2221 ttttaacagc ctctaagaca tcctgactag gagaaatttc tttttccagt tggtcagggt
     2281 catcgtaaaa acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa taagtttggc
     2341 aaagtccaca ggcgatacat cgttcaggta taagtgtgat tttcatgttc atatttatat
     2401 tgtaataaga aaagtaaaaa aaaacaagga gtaaggtatg gcaaaagaac cgtggcaaga
     2461 agatatttat gatcaagaag aatcaagagc agggcatcgg catcgaaacc acggaggggc
     2521 tgataggatg gctaatcgta ttttgacgat cctagctagt attttctttg taattgtggt
     2581 ggtgatggtc atcgttctca tctatctatc atcggggggg agtaatcgca cagcagcctt
     2641 aaaagacttt catgattctg atgcaagtgt agtacaaatc tcatcttcaa gcagttctca
     2701 gcctgagcag agttcagagc cagaatctac ttctagtagt tcagaagaag ctgctaatcc
     2761 tgaaggaacg attaaagttc tcgcaggaga aggggaagca gctattgccg ctcgtgcagg
     2821 aatctccatt gctcagttag aggccttgaa tcctgggcac atggctacag gatcttggtt
     2881 tgctaatcca ggtgatgtta taaaaataaa ataggagccg atatgaaaac aattcaaatt
     2941 gctattgatg gtcctgcttc cagcggtaag agtacggtcg caaagattat tgctaaggat
     3001 tttgggttca cctaccttga tacaggagct atgtatcgtg cagcgaccta tatggctctt
     3061 aagaaccaat taggagttga agaagtcgaa gcccttctag ccttgttgga ccagcatcca
     3121 atcagctttg gacgttcaga aactggagac cagcttgttt ttgtaggaga tgtggatatt
     3181 acccatccta tccgtgaaaa tgaagtgacc aatcatgttt ctgctattgc agcaattcct
     3241 gaagtgcgtg agaaactggt ttctctccaa caagaaattg cccagcaagg cgggattgtc
     3301 atggatggtc gcgatattgg aactgttgta ttgccacaag cagaattgaa aattttccta
     3361 gtagcttctg ttgatgagag agcagagcgt cgttacaagg aaaatattgc caagggaatt
     3421 gaaacagacc ttgaaaccct aaaaaaggaa attgctgcgc gtgactacaa ggatagtcat
     3481 cgtgagactt ctcctctcaa acaagcagag gatgctgtct accttgatac aactggtttg
     3541 aacattcaag aagtagttga aaaaatcaaa gcagaagctg aaaaaagaat gtaaatgtag
     3601 aaaagccgat agattgatat cggttttttt ctaaatttgt caaaatgctg attttagggt
     3661 ataatagttg ctgttcgaga aattttgatt ttcaaagaat agtgaatgat gataaggaga
     3721 aaccatgaac aatttaccaa attgtccaaa atgtaactca gagtatgtct acgaagacgg
     3781 tgctctactg gtttgcccag agtgtgctca tgagtggaat cctgctgaag ttgcagaagt
     3841 agaagaaggt cttgtcgcta tcgatgccaa cggaaataaa ttgactgatg gtgatacagt
     3901 aactctcatc aaggacttga aagtaaaagg tgcgccaaaa gatttgaaac aagggacgcg
     3961 cgtgaaaaat atccgcatcg tagaaggcga tcacaatatc gactgtaaga ttgatggttt
     4021 tggtgccatg aaacttaaat cagagtttgt gaggaagatt taagcatgtc aaaacactat
     4081 aaacttgtat tttatagccg tatcttcttg tttctagcgg cttttacggg agtttatctt
     4141 gaaattacta ggcatggtgg ttttgggatg cttctctatt acacggttct gtccaacctc
     4201 ttggtaacta tttttaccct ttatcttcta aaggttatga gccgtgtagg tgaaaattgg
     4261 caaaggccaa gtctcttgcg cttaaaaggt ggggtcacca tgagtatcat gattacctgt
     4321 gtgatttacc atttcctctt ggcgcccatt gcgactaatt tctataccct agaaaatttc
     4381 ctttgccact atatcgttcc catctggttt ttagcggata ccctcttttt tgacaaacag
     4441 ggtcaataca agatttggga tccagcagtg tggaccattt taccctttct gtatatgatg
     4501 tttgctcttt ttaatggctt ggttctaaaa ctcaatattc caaatgccaa ggataatcct
     4561 ttcccttact tctttttgaa tgtgaacaag ggttggaatg ttgtgtttaa gtggtgtctg
     4621 attatctttg ttgcctatat ggtagcagga tttattttct actttatcaa gcaaatcaag
     4681 agaaagtcat cctaatactc ttcgaaaatc tcttcaaacc acgtcagttt ccatctgcaa
     4741 cctcaaaaca ctgttttgaa caacctgcgg ctagcttcct agtttgctct ttgattttca
     4801 ttgagtataa gatacaaggg attcattttc gaatttaaga aggagtctac aaaccaatga
     4861 ggcttcttct tttcttgctt atttgataac tatcaaaaaa gtagaagatt aagagaaata
     4921 tagaaagaga tttcatgaaa caatttttag aacgggccag cattttggct ctctccctcg
     4981 ttttgattac ctccttttcc atttcgagtg ccctaccagc catgtttgac tattatcagg
     5041 gttattctaa ggaacaaatt gagctcttgg tgagcttgcc ttcctttgga atcatgatga
     5101 tgttactgct aaatggtttc ttagaaaaaa tatttcctga gcgcttacag attagtttgg
     5161 gcttgctgat tttatcattg agcggtacag ctcccttctg gtaccaagcc tatccctttg
     5221 tctttggaac acggcttctc tttggtttgg gtcttgggat gatcaatgcc aaggccattt
     5281 ctattatcag tgaacgctac caaggaaaaa ggcgaattca gatgttaggg ctacgcgctt
     5341 ctgcagaggt cgttggagct tctctcatta ccttggccgt cggtcagttg ttggcctttg
     5401 gttggacagc tatctttcta gcctatagtg ctggattttt ggtgctgccc ctttatctgc
     5461 tctttgtccc ttatggaaaa tcaaagaaag aagtcaagaa aagagcgaag gaagcaagtc
     5521 gtttaactcg agaaatgaaa ggcttgattt ttaccttagc tatcgaagcg gcagttgtag
     5581 tttgtaccaa tacagctatt accatccgta ttccaagttt gatggtggaa agaggattgg
     5641 gggatgccca gttatctagt tttgttctta gtatcatgca gttgatcggg attgtggctg
     5701 gggtgagttt ttctttcttg atttctatct ttaaagagaa actgctcctc tggtctggta
     5761 ttacctttgg cttggggcaa attgtgattg ccttgtcttc atccttgtgg gtggtagtag
     5821 caggaagtgt tctggctgga tttgcctata gtgtagtctt gacgacggtc tttcaacttg
     5881 tctctgaacg aattccagct aaactcctca atcaagcaac ttcatttgct gtattaggct
     5941 gtagtttcgg agcctttacg accccatttg ttctaggtgc aattggctta ctaactcaca
     6001 atgggatgtt ggtctttagt atcttaggag gttggttgat tgtaatctct atctttgtca
     6061 tgtacctact tcagaagaga gcttaggatt gattcctaag tttttctttt gatactcaat
     6121 gaaaatcaaa gagcatagtt gattgagttt ggaatagtac gctgtagtta ctaaaatatt
     6181 tctagaaatt aatttgactt ttctaataga gttattcata tcttatttca atctactata
     6241 gaaagctagc cgcaggttgc tcaaaatagt gttttgaggt tgcagatgga aactgacgtg
     6301 gtttgaagag attttcgaag agtatgagat ttttataccc atacaatatt tgttttaggt
     6361 ccttgtttac agactaattt cttgataaaa tagaggttat gacgagatat aaagcaacta
     6421 tttcctatga tggttatgcc tttgctggct ttcagcgcca gtctcatgcg cgtagcgttc
     6481 aggaagaaat tgaaaaaacc ttgaccagat taaataaagg gcaaaccaat actgttcacg
     6541 gtgctggtag gacagatagt ggggttcatg ccctgggaca ggtcattcat tttgacctgc
     6601 cttatcagat ggatgaggag aaactccgtt ttgccttgga tacccagtct cctgaagata
     6661 ttgatgtgat ttcgattgag cttgtggcag atgattttca ttgccgttat gccaaacata
     6721 gcaagaccta tgagtttatt gtggatagag gacgtcccaa aaatcctatg cgccgtcact
     6781 atgccaccca ctttccctac ccactcgatg tggaacgaat gcagattgca atcaaaaagc
     6841 tagagggaac ccatgatttt accggtttta cagcctctgg gactagtgta gaggataagg
     6901 ttcgcaccat cacagaagct agtttaatag tcgatgagac aggacaattt ttgaccttta
     6961 ccttttcagg aaatggtttc ttgtataaac agattcgcaa tatggtgggg actcttctca
     7021 aaatcggtaa caaccgcatg ccagtagagc agattgatct catcttggag aagaaggaca
     7081 ggcaacttgc aggtcccact gcagcaccaa atggtttgta tttaaaggag attcgttatg
     7141 aagaataatc gtattttagc actttctgga aatgatattt ttagtggtgg tggactgtca
     7201 gctgatttgg ctacctatac cttgaacggc ttgcatgggt ttgtagcagt gacttgtttg
     7261 acagccttga cagaaaaagg atttgaagtc tttccaactg atgataccat ttttcaacat
     7321 gaattagata gcttgcgtga tgtggaattt gggggaatta agattggtct tctccctact
     7381 gtcagtgtgg ctgagaaggc cttggacttt atcaaacaac gcccaggagt acctgtggtg
     7441 ttggatcctg tcttggtctg caaggaaacg catgatgtag ctgtcagtga gctctgccaa
     7501 gagttgattc gctttttccc ttatgtcagt gtgattacgc ctaatctccc agaagcagaa
     7561 ttattatccg gtcaggaaat taaaaccttg gaagacatga aaactgcagc gcagaaattg
     7621 catgatttag gagcgccagc agtcattatc aagggaggca atcgtcttag tcaggacaag
     7681 gctgtggatg tcttttatga tggacagacc tttactatcc tagaaaatcc agttatccaa
     7741 ggccaaaatg ctggtgcagg ttgtaccttt gcctctagca ttgccagtca cttgattaaa
     7801 ggtgataaac ttttgccagc agtagaaagc tctaaggctt tcgtttatcg tgctattgca
     7861 caagcagatc agtatggagt aagacaatat gaagcaaaca aaaacaacta aaatcgccct
     7921 tgtatcccta ttaaccgccc tttctgtggt tctaggttat ttcttaaaaa tcccaacacc
     7981 tacaggaatt ctaactcttt tagatgctgg tgtcttcttt gcggcctttt actttggtag
     8041 tcgtgaagga gcggtagtcg gaggactagc aagtttcttg attgacctct tatcaggcta
     8101 ccctcagtgg atgttcttta gcttggtcaa ccatggcttg cagggatttt tcgcaggatt
     8161 taaaggaaaa agtcagtggt taggccttat tttagcaact attgccatgg taggaggcta
     8221 cgccttgggt tctactttga tgaatggctg ggcagcagcc ctcccagaaa ttctaccaaa
     8281 tttcatgcaa aatatggtag ggatgattgt aggatttatt cttagtcaaa gtatcaagaa
     8341 gattaagtaa tactcttcga aaatctcttc aaaccacgtc agtttccatc tgcaacctca
     8401 aaacactgtt ttgagcagcc tgcggctagc tttctagtct gattttcatt gagcataaag
     8461 aggttgagta aaaagtcttt caaataagaa aaacgcatag tatcaggtgt tgaatgaaca
     8521 cctgatacta tgcgttttat tgtgggaaga ttttcctcat tttctagtga aattgaactt
     8581 tttctaacat cttttgatag atgacttctt aatcaattat catttccatt gttgtttctt
     8641 ggggtttcat cccttgtctt tgataaaagc ggagagcacc ctcgttatca ttccagacac
     8701 ttagggttag attattgcag ccaatttctt tagcataata gcagaaaaat gacaataaaa
     8761 tagcccctag atattttgaa aggaaagcat aggggctata tagtttaatc aaaataaagc
     8821 aaatctttgc tggtgcttgt aaagaggtcg aagccatcct tggtaacaac accgcagtct
     8881 tcaatacgaa caccgacttt accagggata tagatacctg gttcaacaga gaagcacatg
     8941 ccttcttcga tgaccatgtc gtttccttcc atgatagatg ggaattcatg gacatccata
     9001 ccgataccat gcccgagacg gtggttgaag tactcaccat aaccagcttt ttcgatgacc
     9061 tcacgggcag cgcggtccac ttcatgagca gtcacacctg gcttgataaa gtcaagagca
     9121 gcttgttggg cttcaagagt caagttgtaa atatctttct tgaattggtc tggtttgccg
     9181 acagcgactg tacgagtcat atctgacgca tagccattga ccagaacacc caggtcaaag
     9241 aggagaagag catcattttc aaccttatta gctgctggaa tgccgtgtgg attcgcagca
     9301 ttatcaccag tcaagaccat ggtatcaaag ctcatttcgt aaccttcacg tttcatggca
     9361 aagtcaattt gtgcgatgat atctgtctca gtcttatcaa gagaaatatt gtcaaaacca
     9421 acatgaacag ccttgtcagc ataaagacct gcaaccatca ttttttgcac ttcatcagct
     9481 gatttgatga ggcgcatgcg ttggatacga ggagtgaggt tgtcaaactc agcagtctca
     9541 aaaactgttt tcaaaccatg gtatttggtc aagatgagat tgtcaaactc aacagcgaca
     9601 cgtttgaagt caagttgtgg aagagcatgt ttgatttttt gccatggatt ttcagaatcg
     9661 acatagccca ctactgggaa ggaaacggtg ctacttgcac gttctacttc aagagctggg
     9721 acaaagagga gaggttcctg atctgctagg acaaagagga acatttggcg ttcatgggga
     9781 tcactgtaaa aaccagtgag gtaattgatt gtgacggggt cagatacgac agcgacgtct
     9841 agtttttctg attcaagata tgttaggatt tgttgtaatt tagacatatg ctaccttctt
     9901 tctatccctc tattttggca aaaaatgaga gaaaatgcaa gggagaaggg taaaagaaaa
     9961 gacaaaaaac tccgacaaga taacggagtt ctttgatatc attttccttt gtttaagaaa
    10021 agtcagcctt gcttttgacg tcactgtact cttcagcgat ttcttggctg aggatatcct
    10081 cataggcagg gagttggata tcctgaccat atttcttctt gagggcagta gtaactaggc
    10141 gataagccag attggcatta cgagagagga taggcccgtg gaagtaggaa ccaaagacat
    10201 tcttataatg aaccccttca ccgacctttt cttcgttgtt tccatttcca tagacaacct
    10261 gtcccagcgg tttttggtca tcagagagga aggtacggcc ttggtgattt tcaaatccat
    10321 agtaggtttc atcgaaatct tcattgtgaa tcttgatgtc accgataaaa cggttattgg
    10381 tctggttgag cgtgtagtgt cccatgaccc ctagcccttc gatacgtttt cctgaagctt
    10441 caacataata ttgacccaat agttggaaac caccgcagat agccagaact acaccgtcgt
    10501 tttggatgta gttgtcaatg ctctcttttt tagcaggtag gtcgtctgca atgatacttt
    10561 gttcaaagtc ttgaccacca ccgaaaaagg cgatgtcgta gtgattttca tcaaagtcat
    10621 catggagaga aacgatgtca acggtcacat gggctcccag tttttcagcc acatacttga
    10681 gcatgaggat gtttccattg tccccgtagg tattcatgag atttccgtag aggtgggcaa
    10741 tgttgagctg ataggggtaa ttgccatctt ttgaggaaag tgaagtataa accattagtt
    10801 catctccttt ctaacaatct gacgactagc cagcagttca cgaaattcca gcatggcagt
    10861 ataagttgcc agaatatagg catgcttgca gtcttgattc tcaatggtct tgagaacttg
    10921 ctccagatta ctcgtttcag tgattttctc agctggatag ccagtcactc ggaggcgacg
    10981 agcgatttca gaatgacgaa caccgccagc gttgatttca ggaatgtcca tgtcagtgat
    11041 ttgttcaaag tctgcatccc agatccagct agtgtcaatt ccatctgcat agttggcatt
    11101 aaggaggaca gataggctaa atggataagg tgctagtttg atcatttcga tagcttgggt
    11161 tgcaccgact ggatttttaa tcaagacaag ggtacattcc ttgtcaccga tatgaaaggt
    11221 ttcttggcgt ccaaagacag cacggctctt gtcaaatccc tgtttgatga gttgcgaatc
    11281 ggcacctagg aaacgggcga tggccacagc agctagggcg ttatagatat tatagagccc
    11341 gccgatttgg ataccgtatt cttggccgtc tatgacaaag cgagagcgat tgttggtcaa
    11401 ctcaaccagt tttgtcaaac gatagtcgag atcaggacgt ttgcatccac aaccttcaca
    11461 gatataggca cccaagtttg cataggtatt atgctcatat ttgaggatgc cttggcagtc
    11521 aggacagaga atcccttcgg tattgtagtg agccagttgg gctggtcctt tttccaagtc
    11581 aaaaccaaaa tactctatag ggtttggaat agttggcttg tagaaaagtg gactgtctcc
    11641 gttaaggaga acagtagcag ttggaacttt ccgaatggct tccaatatca tgttataggt
    11701 agtatagatt tcaccgaaac ggtccatctg gtcacggaag atattagtaa tgacaaaaag
    11761 actaggctgg atatagtcac agatacgaga tagactggct tcgtcaattt cgaggacggc
    11821 aatatttttc ccagtttttg aagatttggc tgttaggaag gttgttgcaa tccctgtaat
    11881 catgttggca ccgcttgggt tggttagaac ttgaccataa acctctttta aaatgccgac
    11941 agtgagggca gttgtcaggg tttttccatt tgttccagtg acaacgacaa tctcgtagtt
    12001 cttagctagg ttttgtaaaa tatctttatc aaattgaagg gcgactttac ctgggagcgt
    12061 acttccacgt ccaagacggc ttaaaacgaa gtgggaagaa cgcccagcaa gaaggcccaa
    12121 agtagttttt aagttcatgt ttctattata tcacaaaaga gggaaaagac agatttggtg
    12181 tttcgtagaa gtaaaaacag cccaaagagg gctgtcagtt aagatgagat ttcaacttaa
    12241 atcgcaaaca agtcattcaa gttctcagcc aaggttgggt gagtgaagat ttgttttgtg
    12301 aagtaagtgt aaggaatctt gttgtccata gcaacagtaa tgatgttgat gatttcttga
    12361 gaaccttctg agaagatgct tgcaccaaga atttcttttg tttcagtatt aacaacagct
    12421 ttgaaagttc cgcgaaggtc tccatttacg tgaccacgag gcatggctgc aacagggatt
    12481 tctttcactg cgtatggaag tttcaaatca gctgcttggc tttcagtcaa accaacttgt
    12541 gaaagtgcag gtgtgatgaa catagtattt ggcacattga gacggtcctc aagtgtgtag
    12601 ctgccatctc cagcaaggta gctgtaaaca acacggaagt catcaagtga aatgtaagta
    12661 aattgaagac caccgttgac atctccaact gcaaagacac caggaacgtt tgtttgacag
    12721 tgtttatcta ctttaatagc gccacgttca gttagttcaa tatctgtatt ttcaagttga
    12781 agtggttcta catttggttt gcgtccagtt gcgtagagaa gggcgtcgaa acggtaagtt
    12841 tcgtcttcag ttacgacaag cacttggtca ccgtcgtttt taatttcagt agtatggata
    12901 ttttgaagca attcaatacc gtcttcttcc aggtattgtt tagcaagagc tgcgatggaa
    12961 ggttctgcac gaggtaggaa tgtatccaag gcatctagga ctgtaacctt gcttcctagt
    13021 ttattgtaaa ggccagcaaa ttcaagaccg atatttccgc caccaaggac tccaagtttt
    13081 tcaggcaatt tatccaagct ttggatacct gttgagtcaa agacgttttt gcttgtagca
    13141 agtccaggga ttggcaagac gtttgaaaca gcaccagtgt tgatgacgat agtttcagca
    13201 gtcaattctt gtttttcatc accagcttgg atttcgatga ctttatttga aaggaagtga
    13261 gcttcagcat caaagatatc gacgccagta ccagcaacag tcgtatagtt tttaccgttg
    13321 aggcgaccag tgatcgtgtt tttggtagca atgacttctt caaaagacaa gtctttctca
    13381 gcagcaacca gcaaagtttt agttgggata caaccgatgt tgatacaagt tccaccgtac
    13441 atagctttgc tacgttcaac gagggcaact tttttgccag ctgaagccaa tttaccagct
    13501 agtgttttac cagctttacc aaatccgata acgattaaat cataagttaa catttagaat
    13561 tcctcctatt cgaattacat tctagcacaa gaaaaaaact tttgcacaat tctgctacga
    13621 aaaagacaga aaaatatgaa aacgctttcc aggcaaaaaa ctagtaattt tttgacaagc
    13681 ttgataaact aaaatcctat ctatttttat ataagataga ataaatgttc gaaaatagga
    13741 ggttttatga aatcgaatcg ttatattatt gcctttgctg gggtcatttt acacttaatg
    13801 ctgggttcga cttatgcctg gagtgtttat cgtaacccta tcattgaaaa aacgggatgg
    13861 gatcaggctt ctgttgcctt cgcctttagt ctagcaatct tttgtttggg cttatcggct
    13921 gcatttatgg ggcgtttggt agaaaaattt ggtccgaaag tcatgggaag tctatctgct
    13981 tttctatacg caggtggaaa tatcttagca ggatttgcaa tagaccgtca ggagctgtgg
    14041 ttgttgtatc tcgcttatgg cattttaggt gggcttggtt tgggagcagg ctatattacc
    14101 cctgtgtcga cgattataaa atggtttcct gataaacgtg gtctcgcaac aggtttagcg
    14161 attatggggt ttggttttgc ttctttattg actagtccca tagcgcaaca cctcatcgca
    14221 ggggtagggc ttgtagaaac tttttatatt ttaggagcaa gttactttat tatcatgctc
    14281 ctagcttcac aattcattaa gcgtccaaat gagcaagagc ttgcaatttt atcttcttca
    14341 gggaaagaaa aaacagcctc tttgacgcaa ggaatggctg caaatcaggc tctgaaaagc
    14401 aatcggtttt atatgctttg gattattttc tttatcaaca tagcttgtgg tttaggctta
    14461 atttcagcgg catcgccaat ggcacaggag atggctggct tgtctacaag tcatgcagca
    14521 gtaatggtgg gtgttttggg gattttcaat ggatttggtc gcttgctctg ggcgagtttg
    14581 tctgactata tcggtcgccc tctaaccttt agtatattac tgcttgtcaa tcttttcttt
    14641 tctctctcac tttggctctt tacagattcc gttttatttg tagttgctat gtctattttg
    14701 atgacttgct atggagctgg tttttctttg attccagctt atctcagtga tatttttgga
    14761 accaaggaat tggccgctct gcatggttat attttaacag cttgggcaat ggctggttta
    14821 gcgggaccta ttttattagc agagacttat aaaatggctc attcgtacac acaaaccttg
    14881 ttcgtttttc tcattttata cagtatcgcc ttggctttgt cttattatct aggtcgttca
    14941 atcaaaaaag aaagtcaaaa accgcttaca tgattttctg tagaaatggg gctatctttt
    15001 gctctggtct tgtgttatac tagataggtt gcaaagaaaa cagtactttt cttttgtgga
    15061 aaagaagcaa cacgatttta tatctagtta tatgaaaata cgtcataaaa agaaaagtat
    15121 aaactaagcc ctatagggtg gcttcgcacc acctttagaa agaagaataa cgtgaaattt
    15181 aatgaattaa acttgtctgc tgatttgcta gcagaaattg aaaaagctgg ttttgtagaa
    15241 gctagtccta tccaagaaca aactattcct ttggcccttg aaggcaagga tgttatcggt
    15301 caagctcaga ctggtacagg aaaaactgca gcctttggct tgcctaccct tgaaaaaatc
    15361 cgtacagaag aagcgactat ccaagccttg gtcatcgctc caactcgtga actagctgtc
    15421 caaagtcaag aagaactctt ccgctttggt cgtagtaagg gagtcaaagt ccgttcagta
    15481 tatggcggat caagcattga aaaacaaatt aaggctctta aatctggtgc ccatatcgtg
    15541 gtgggaactc caggtcgcct cttggacttg attaaacgca aggccttgaa attacaagac
    15601 attgaaaccc ttatccttga cgaagcggat gaaatgctta acatgggctt ccttgaagac
    15661 atcgaagcca ttatttcccg tgtacctgag aaccgtcaaa ctttgctttt ctcagcaact
    15721 atgccagatg ccatcaaacg tatcggtgtt cagtttatga aagcccctga acatgtcaag
    15781 attgcggcta aggaattgac aacagaattg gttgaccagt actatatccg tgttaaggaa
    15841 caagaaaaat ttgacaccat gactcgtctc atggatgtgg cacaaccaga actcgctatt
    15901 gtatttggtc gtaccaaacg ccgtgtggat gaattgactc gtggtttgaa aattcgtggc
    15961 ttccgtgcag aaggaattca tggcgaccta gaccaaaaca aacgtcttcg tgtccttcgt
    16021 gactttaaaa atggcaatct tgatgttttg gttgcgacag acgttgcagc gcgtggtttg
    16081 gatatttcag gtgtgaccca tgtctacaac tacgatattc cacaagatcc tgagagttat
    16141 gttcaccgta tcggtcgtac aggtcgtgct ggtaagtcgg gtcaatctat tacttttgtt
    16201 gctccaaacg aaatgggtta ccttcaaatc attgaaaact tgactaagaa acgcatgaaa
    16261 ggtctcaaac ctgcaagtgt agaagaatcc ttccaatcaa aaaaacaggt agctctcaag
    16321 aaaatcgaac gtgattttgc agatgaaacc attcgtgcca actttgagaa atttggtaag
    16381 gatgctcgca aattggctgc tgagtttact ccagaagaat tggcaatgta tatcttgagt
    16441 ctgacagtcc aagacccaga tagccttcca gaagtggaga ttgcacgtga aaaaccacta
    16501 ccgtttaaac catcaggtaa tggtttcggt ggtaaagcta agggaggtcg tggaggccgt
    16561 cgtggggacg accgtcgaga gcgtgatcgc cgtggcaatg gtcgccgtga tgagttcaaa
    16621 aaaggaagtc gtggcaacga tcgttttgat aaggaaaaac gttaccgtaa ggataataaa
    16681 aaaccacgca atactttaag cgaaaagcaa acaggctttg ttattcgtaa caaaggcgat
    16741 aaataagaaa aagcggttca aaatgaatcg cttttttata taaggagacc gaatgtgaaa
    16801 agacaaataa aattattata ttatcttttg taatgttatg atacacaaaa ataggcaact
    16861 tgtcaataga aaaggaacaa tttaattaaa aatattctgg tttttaatta aattgtaagt
    16921 caatgcaagt caataaggaa ttttcagata attattgaaa aagagacgtt tttatgttat
    16981 aatgatagcg attaaattcg aggtgaaaaa tggcacattt attagaaaaa actagaaaaa
    17041 ttacatcaat tttgaaacgc tcagaggagc agttgcagga tgagctccct tacaacgcta
    17101 ttacgcgtca gttagcggat attattcatt gcaatgcctg cattatcaat agtaagggac
    17161 gtctgcttgg ctattttatg cgttataaaa caaatacaga tcgcgtagag caattcttcc
    17221 aaactaagat tttcccagat gactacgttc aaggggctaa tatgatttac gaaacagaag
    17281 caaacttgcc tgttgagcat gatatgagta ttttccctgt tgagagtaga gatgattttc
    17341 cagatggctt gacgactatt gcaccgattc atgtatcggg gattcgcctt ggttctttga
    17401 ttatttggcg taatgataaa aaattcgaag atgaggactt ggttcttgtt gagattgcca
    17461 gtaccgttgt tgggattcag cttcttaact tccaacgtga agaagatgag aaaaatattc
    17521 gtcgtcgtac tgctgtcacc atggcggtca ataccctttc ttactccgaa ctccgtgctg
    17581 tttcagcaat tttaggggaa ttaaatggaa atgaagggaa gttgactgcg tcagtgattg
    17641 cagatcgtat cggaatcact cgctctgtga ttgtcaatgc tcttcgtaaa cttgagtctg
    17701 cggggattat tgaaagtcgc tcacttggaa tgaagggaac ctatcttaag gtcttgattt
    17761 cagatatttt tgaagaagtg aagaaaagag attactaatg acaaaggctt taatttcgat
    17821 tgattataca gaagattttg ttgctgatag tgggaagctg acagcaggtg ctccagctca
    17881 ggcgatttcg gatgccatta gcaaggtaac tagattagct tttgaacgag gagattatat
    17941 cttctttact attgatgctc atgaagaaaa cgattgtttc catccggaaa gtaagttatt
    18001 tcctcctcat aatctgattg ggacgagtgg acggaattta tatggagatt tggggatctt
    18061 ttatcaagag catggttcag acagtcgtgt cttttggatg gataaacgcc attactcagc
    18121 tttttcaggg actgacctag atattcgttt gagagagcgt agagtgtcta ccgttatctt
    18181 aacaggtgtc ttgacggata tctgtgtcct acatacagct atagatgcct ataatctagg
    18241 atatgacatc gagattgtta aaccagctgt tgcttccatc tggcctgaaa atcatcaatt
    18301 tgccctaggt catttcaaaa atacactcgg agctaagtta gtagatgaaa atctaaatga
    18361 actttctgag taacctggtt ggtgaaaatg aaaaaatttg aaaaaaagtg ttgacaagca
    18421 tcccaaaagt tgatatacta gtaaagtaat cgacgcgggg atggcggaat tggcagacgc
    18481 gcaggactaa ggatcctgtg accgctttag gtcgtgaggg ttcaagtccc tctctccgca
    18541 taggaaaaga gttagctaaa gctagctctt ttgtatttct ctaaaaaatt agaatccagt
    18601 caaatgtagt ggagaatcag cgaaaatatg ggaaaactga tccttgtttc tgcttttgtc
    18661 atagaagaat aataaagatt atcttcttca aattctccga tattctctaa agttttgtgc
    18721 aagttgcaca gaactttttt atttttttgg tcatcttgcc atagaaatat aaagcgtttt
    18781 catctataat ataattatca aaagacaaaa ggagttcacc tcatggtaga attgaatctt
    18841 aaaaatattt acaaaaaata tccaaacagc gaacactatt cagttgaaga tttcaacttg
    18901 aacatcaaag ataaagaatt tatcgttttc gtaggacctt caggatgtgg taaatcaact
    18961 acactccgta tgattgctgg tcttgaagac attacagaag gtactgcatc tatcgatggc
    19021 gtggttgtca acgacgtagc tccaaaagac cgtgatatcg ccatggtatt ccaaaactac
    19081 gctctttacc cacacatgac tgtttatgac aacatggctt tcggtttgaa attgcgtaaa
    19141 tacagcaaag aagacattaa caaacgtgtt caagaagcag ctgaaatact tggattgaaa
    19201 gaattcttgg aacgtaaacc agctgacctt tcaggtggtc aacgtcaacg tgttgccatg
    19261 gggcgtgcga ttgtccgtga tgcgaaagta ttcttgatgg acgaaccttt gtcaaacttg
    19321 gatgccaaac ttcgtgtatc aatgcgtgct gaaatcgcta aaattcaccg tcgtatcgga
    19381 gctacaacta tctatgtaac tcacgaccaa acagaagcga tgacacttgc agaccgtatc
    19441 gttattatgt cagctactaa gaaccctgct ggtacaggta ctatcggacg tgtagaacaa
    19501 atcggtactc ctcaagaagt ttacaaaaat ccagttaaca aattcgttgc aggattcatc
    19561 ggaagcccag ctatgaactt catcaacgtg aaattggttg gtagcgaaat tgtttctgac
    19621 ggtttccgtt tgaaagtgcc agaaggagca ttgaaagttc ttcgtgaaaa aggctacgaa
    19681 ggaaaagaat tgatctttgg tatccgtcca gaagacgtga atgcagaacc tgctttcctt
    19741 gaaacattcc cagactgtgt tgtaaaagcg actatctctg tatcagaact gcttggttca
    19801 gaatctcacc tttactgcca agttggtaaa gacgagtttg ttgcaaaagt tgatgctcgt
    19861 gactacttgc aaacaggtgc aacagttgag cttggatttg acttgaacaa agcacacttc
    19921 ttcgatgtag aaactgaaaa aacaatctac taaaataaat aaaattcaaa gcactacaag
    19981 aaaagatatc tctttatcaa ttgtagtgga gagatatcag ttaatctagg gagagaaaca
    20041 aaatgcttct ctcctttttg ctagggaagt catattatgc atctatattg tgatgctctt
    20101 taatactctt cgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgta cgtatgatta
    20161 ctgatttcgt cagttttatc tgcaacctca aagatgtact ttgagcagct tacggctagt
    20221 ttcctagttt gctctttgat ttccattgag tattatttgt gggtaccatc tacaagtgaa
    20281 gctatatgcg taaactacgt gagcaattga attcgaacta gagaggtaat aataaattta
    20341 tgctatagtt atggtgactt gtatgctttt gattctagtt tatcaaataa tagattagaa
    20401 ttgtcagata atatcatttt gtgttataat gaagaaaaaa cagaggtgtt caaatgtcag
    20461 aagcaggtca taagttttta gcaaaattgg ggaaaaaacg cttacgtcca ggtggaaagc
    20521 gtgccacaga ttggttaatt gcagaaggag gattttcaaa agaaaagaga atactagagg
    20581 ttgcgtgtaa taggggaact acagcaattg agttggcaca gcgttttggt tgcaagataa
    20641 ctgctgttga tatggatgct caagctttag aagtggctaa aaaatctgct ggaacggcag
    20701 gtgttgctca tttaatcagt tttgaaagag caaatgcaat gaaacttcct tatcaagatg
    20761 ctagttttga tattgttata aatgaagcta tgctgactat gcaagccgat caagctaaga
    20821 aaaaatgtgt aatggaatat ctaagggtat taaaacctgg aggtcttctc ttgacacatg
    20881 atgtgcttct taaggaagct aaagagtcta tcagacagga attatcacaa gcaattcatg
    20941 taaatgtagg tcctttaact caagatggtt gggaacaggt gatgatagaa tcaggttatt
    21001 gtgatgtgaa agcattgact ggtgaaatga cattaatgaa attatcgggt atgatttatg
    21061 acgaaggttt gctaggaact ttgaaaattt gtgtaaatgc ttgtaaaaag gagaatagaa
    21121 agcagttttt aactatgtat aaaatgtttg ctaagaataa acagaaattg ggctttattg
    21181 cgatggctag ttataaatcg tcaaaacgtt agataattat tgaagttaac ttttcctttt
    21241 ttctttctta aaaaatatgc tataatagag agtaaaaaac tttgaaagaa agaaaaaaga
    21301 tgaatttaaa agattacatt gcaacaattg aaaattatcc aaaggaaggc attaccttcc
    21361 gtgatattag tcctttgatg gctgatggaa atgcttatag ctacgctgtt cgtgaaatcg
    21421 ttcagtatgc tactgacaag aaagtcgaca tgatcgtggg acctgaagct cgtggattta
    21481 tcgtgggttg tccagttgcc tttgagttgg gaattggttt tgcgcctgtt cgtaagccag
    21541 gtaaattgcc acgtgaagtt atttctgctg actatgaaaa agagtacggt gtcgatacct
    21601 tgactatgca cgcggatgcc attaagccag gtcaacgtgt tcttattgta gatgaccttt
    21661 tggcgacagg tggaactgtt aaggcaacta tcgagatgat tgaaaaactt ggtggtgtta
    21721 tggcaggttg tgccttcctt gttgaattgg atgaattgaa cggccgtgaa aaaattggtg
    21781 actacgacta caaagttctt atgcattatt aatgaaaaca gtccctaggg ctgttttctc
    21841 tacactatga tataaaaata gactataact agttagagaa aaactataat tgaaaactat
    21901 atcttcttgc agtataataa aaggactaag tgtttgagat ttgtcttcaa acatatgcaa
    21961 ttattcctga aagagtacag ttaggagagg gttatgccga ttcgaattga taaaaaattg
    22021 ccagctgttg agattttacg gacagagaat atctttgtca tggatgatca acgtgctgcc
    22081 caccaagata tccgtccttt gaagatttta attttaaatc tcatgccaca gaaaatggtc
    22141 acagagaccc agttgttgcg ccacttggct aatacacccc tacaactgga tattgatttt
    22201 ctctatatgg agagccaccg ttctaaaaca actcgttcag agcacatgga gaccttctat
    22261 aaaacttttc ctgaagtcaa ggatgagtat tttgatggga tgatcatcac gggtgctcca
    22321 gttgagcatt taccatttga ggaagtggac tattgggagg aatttagaca gatgcttgag
    22381 tggtctaaga ctcatgtcta ttcgaccctt catatctgtt ggggggctca ggctgggctt
    22441 tatctgcgct atggtgtaga aaaataccag atggacagta agctatcagg tatttatcct
    22501 caggacaccc taaaagaggg tcaccttcta tttagaggct ttgatgatag ctatgtatcc
    22561 cctcattcac ggcacacgga gatttctaag gaagaggtct taaacaagac caatctcgag
    22621 attttatcag aaggacctca ggttggggtt tctattttgg ccagtcgtga tttacgagaa
    22681 atttatagtt ttggtcattt ggagtatgac cgtgatacct tggcaaaaga gtattttcga
    22741 gatcgtgatg caggtttcga cccacatatt ccagaaaatt actttaaaga tgatgatgtt
    22801 aatcaggtac cttgtctttg ttggtcttca tctgcagccc tctttttcag taattgggta
    22861 aaccatgcgg tctatcagga gacgcctttt gattggagaa agatagaaga tgatgcatct
    22921 gcatatgggt atttataaga ggaattatga catatttaga cgcttttaaa tcaggtacct
    22981 tggttttacc gagtgccctg ctcttgcatt ttaaggaact ctttccttct agcgacgatt
    23041 ttctggtttg gcaatttttc tatttgcaaa atacgacagg cttagaagaa atgtcgccaa
    23101 gccagattgc tgaaaggatt ggcaaggaaa tttcggatgt caaccagtcc atttctaatc
    23161 tgacggaaag gggactgctc cagtatcgta ctatcgaatt aaatggcgaa attgaattgc
    23221 tctttgatgc tagtttggcc ttggaacgtt tggatgacct gtttggagca gttcattcaa
    23281 gttcagacca gctaacatct caaaaccagc tcaaggattt ggtggaaacc ttccagcagg
    23341 agttgggacg attgttgacg ccttttgaga ttgaggattt gaccaagaca ctaaaggaag
    23401 atggaaccag tgctgacttg attaaggagg ctcttcgtga agctgttttg aatggaaaac
    23461 caaactggaa gtacattcag gcgattttga gaaactggcg ccatgaagga atcaagagtg
    23521 tggctcaaat tgaggccaag agagcagaaa gagaagcaag caatcctcag ttgacacagg
    23581 tatctgcaga tttcagaaat gccatggatc tctggaagga ttaatccatg caagtaggct
    23641 tgaaatccga gtaagatttg caagctgtgt ataattgtga tagaataaat agaaaataaa
    23701 ttgaaaaaag aggtatgtga aatgtcacgt aaaccattta tcgctggtaa ctggaaaatg
    23761 aacaaaaatc cagaagaagc taaagcattc gttgaagcag ttgcatcaaa acttccttca
    23821 tcagatcttg ttgaagcagg tatcgctgct ccagctcttg atttgacaac tgttcttgct
    23881 gttgcaaaag gctcaaacct taaagttgct gctcaaaact gctactttga aaatgcaggt
    23941 gctttcactg gtgaaactag cccacaagtt ttgaaagaaa tcggtactga ctacgttgtt
    24001 atcggtcact cagaacgccg tgactacttc catgaaactg acgaagatat caacaaaaaa
    24061 gcaaaagcaa tctttgcgaa cggtatgctt ccaatcatct gttgtggtga atcacttgaa
    24121 acttacgaag ctggtaaagc tgctgaattc gtaggtgctc aagtatctgc tgcattggct
    24181 ggattgactg ctgaacaagt tgctgcctca gttatcgctt atgagccaat ctgggctatc
    24241 ggtactggta aatcagcttc acaagacgat gcacaaaaaa tgtgtaaagt tgttcgtgac
    24301 gttgtagctg ctgactttgg tcaagaagtc gcagacaaag ttcgtgttca atacggtggt
    24361 tctgttaaac ctgaaaatgt tgcttcatac atggcttgcc cagacgttga cggtgccctt
    24421 gtaggtggtg cgtcacttga agctgaaagc ttcttggctt tgcttgactt tgtaaaataa
    24481 tcagtaagta gcaaaagcta ggtggaacag cattcagatg tctgttacat tttttatagg
    24541 agagcaaaga ttgaaaacaa aaattggatt agcaagtatc tgtttactag gcttggcaac
    24601 tagtcatgtc gctgcaaatg aaactgaagt agcaaaaact tcgcaggata caacgacagc
    24661 ttcaagtagt tcagagcaaa atcagtcttc taataaaacg caaacgagcg cagaagtaca
    24721 gactaatgct gctgcccact gggatgggga ttattatgta aaggatgatg gttctaaagc
    24781 tcaaagtgaa tggatttttg acaactacta taaggcttgg ttttatatta attcagatgg
    24841 tcgttactcg cagaatgaat ggcatggaaa ttactaccta aaatcaggtg gatatatggc
    24901 ccaaaacgag tggatctatg acagtaatta caagagttgg ttttatctca agtcagatgg
    24961 ggcttatgct catcaagaat ggcaattgat tggaaataag tggtactact tcaagaagtg
    25021 gggttacatg gctaaaagcc aatggcaagg aagttatttc ttgaatggtc aaggagctat
    25081 gatgcaaaat gaatggctct atgatccagc ctattctgct tatttttatc taaaatccga
    25141 tggaacttat gctaaccaag agtggcaaaa agtgggcggc aaatggtact atttcaagaa
    25201 gtggggctat atggctcgga atgagtggca aggcaactac tatttgactg gaagtggtgc
    25261 tatggcgact gacgaagtga ttatggatgg tgctcgctat atctttgcgg cctctggtga
    25321 gctcaaagaa aagaaagatt ttaatgtcgg ctgggttcac agagatggta aacgctattt
    25381 ctttaataat agagaagaac aagtgggaac cgaacatgct aagaaaatca ttgatattag
    25441 tgagcacaat ggtcgtatca atgattggaa aaaggttatt gatgagaacg aggtggatgg
    25501 tgtcattgtt cgtctaggtt atagcggtaa agaagacaag gaattggcgc ataacattaa
    25561 ggagttaaac cgtctgggaa ttccttatgg tgtctatctc tatacctatg ctgaaaatga
    25621 gaccgatgct gagaatgacg ctaaacagac cattgaactt ataaagaaat acaatatgaa
    25681 cctgtcttac cctatctatt atgatgttga gaactgggaa tatgtaaata agagcaagag
    25741 agctccaagt gatacagaca cttgggttaa aatcatcaac aagtacatgg acacgatgaa
    25801 gcaggcgggt tatcaaaatg tgtatgtcta tagctatcgt agtttattac agacgcgttt
    25861 aaaacaccca gatattttaa aacatgtaaa ctgggtagcg gcttatacga atgctttaga
    25921 atgggaaaac ccttattatt caggagaaaa aggttggcaa tatacctctt ctgaatacat
    25981 gaaaggaatc caagggcgcg tagatgtcag cgtttggtat taagcgatga tttgaaagag
    26041 ggatgtgata gtagcaccct ctttttcttt gttttatgat agttcatcct cgagtaaatt
    26101 caagatcttg ctcggaaatg aagcttatat agtagattga atatagacaa ataccttgtg
    26161 attggtaaaa cattttagaa attcatttac ctttcctaat cgacttggtt tcatcttatt
    26221 tcaatctatt atagtattgg ggaatttctt caaaccacat cagcttggtc agttctacct
    26281 gcgacctcaa aacttgtgct ttggtcaagc tgggtttagt ttcctagttt gctgatggat
    26341 ttccattgac tataagcatc caaccctctt tttgtcttct aaagaattct taaattatca
    26401 gtctattgca acttttctca tataagttct ttgtcttgct attggttttc cttagtagta
    26461 tactaaggta gtaatcatta agaagtggtt acaaaaaata atgaatgagg taaaataaaa
    26521 tggtagaatt gaaaaaagaa gcagcaaaag atgtcgcaac attgacaaaa gcagcgccag
    26581 tagcattggc aaaaacaaag gaagtcttga accaagctgt tgctgatttg tatgtagctc
    26641 acgttgcttt gcaccaagtg cactggtata tgcatggtcg tggtttcctt gtatggcatc
    26701 caaaaatgga tgagtacatg gaagctcttg acggtcaatt ggatgaaatc agcgaacgct
    26761 tgattacact cggtggaagc ccattctcta ctttgacaga gttccttcaa aacagtgaaa
    26821 tcgaagaaga agctggtgaa taccgtaatg ttgaagaaag cttggaacgt gttctagcta
    26881 tttatcgcta cctcatcact cttttccaaa aagcgttgga tgtgactgac gaagaaggcg
    26941 atgatgttac aaacgatatt tttgttggtg ctaaggctga acttgagaaa acagtttgga
    27001 tgcttgccgc agaacttgga caagcacctg gtttgtaaga aacaagacaa catagataaa
    27061 tctgtaggaa atttcttaca gattttttct attttgtaag ctattccaaa ccagtctttt
    27121 tttgagtttt ttgataaaat agtactatca gtgaaaagga tggaagcatg actaagaaaa
    27181 tcgtagctat ttgggcccag gatgaagagg gtgtgattgg taaggacaat cgtctgcctt
    27241 ggcatttgcc agcagaattg cagcacttta aagaaacaac tctgaatcat gctatcttga
    27301 tggggcgggt aacctttgat ggaatggggc gtcgcttgct tccaaaacgg gagaccctga
    27361 ttttgacgcg taatccggaa gaaaagatag atggggttgc tacttttcag gacgtccagt
    27421 ctgttcttga ctggtatcag gctcaagaaa agaatctcta cattatcggt gggaagcaaa
    27481 tttttcaggc ttttgaagct taccttgatg aagtgattgt cactcacatt catgctcggg
    27541 tggaaggaga tacctatttc cctgaagagc ttgacttgtc tctttttgag acagtttcaa
    27601 gcaaatttta cgccaaagat gagaagaatc cttatgattt taccatccaa taccgcaaga
    27661 gaaaggaagt ttaatggaac ggagtttatt tggtctattc acggcttttc tgtgtttcat
    27721 ctgctttctg gcaggagcac aagcttttcg taaaaagcgt tacgggcttt ctatcctcct
    27781 ttggttaaat gcctttacca atctggtcaa tagtattcat gctttttaca tgaccttatt
    27841 ttagatagaa tgacagtata gaatggaagg aaatcatgtc tacaaataga aaaaatgata
    27901 tgatggttta ttgctcattt tgtggcaaaa accaagaaga agtacaaaaa ataattgctg
    27961 gcaacaatgc ttttatttgt aatgaatgcg tggagttagc tcaggaaatc attcgagaag
    28021 aattggttga ggaagtcttg gcagacttgt ctgaggtgcc aaaaccaatt gaactcctcc
    28081 atatcttgaa ccactatgta attggtcaag atcgtgccaa gcgtgccttg gcagtggcgg
    28141 tttataacca ctacaaacgc atcaatttcc acgatacacg cgaagagtca gaagatgtgg
    28201 atttgcagaa gtcaaacatt ttgatgattg gcccaactgg ttcagggaaa actttccttg
    28261 cccagacctt ggctaagagc ttgaatgtac cttttgctat tgcggatgcg acagctctga
    28321 cggaggctgg ttatgtgggt gaggatgtgg aaaatatact cctcaaactc ttgcaggttg
    28381 ctgactttaa catcgaacgt gcagagcgtg gcattatcta tgtggatgaa attgacaaga
    28441 ttgccaagaa gagtgagaat gtgtctatca cacgtgatgt ttctggtgaa ggggtgcaac
    28501 aagcccttct caagattatc gagggaactg ttgctagcgt accgcctcaa ggtggacgca
    28561 aacatccaca acaagagatg attcaagtgg atacaaaaaa tatcctcttc atcgtgggtg
    28621 gtgcttttga tggtattgaa gaaattgtca aacaacgtct gggtgaaaaa gtcatcggat
    28681 ttggtcaaaa caataaggcg attgacgaaa acagctcata catgcaagaa atcatcgctg
    28741 aagacattca aaaatttggt attatccctg agttgattgg acgcttgcct gtttttgcgg
    28801 ctcttgagca attgaccgtt gatgacttgg ttcgcatctt gaaagagcca agaaatgcct
    28861 tggtgaaaca ataccaaact ttgctttctt atgatgatgt tgagttggaa tttgacgacg
    28921 aagcccttca agagattgct aataaagcaa tcgaacggaa gacaggggcg cgtggacttc
    28981 gctccattat cgaagaaacc atgctagatg ttatgtttga ggtgccgagt caggaaaatg
    29041 tgaaattggt tcgcatcact aaagaaactg tcgatggaac ggataaaccg atcctagaaa
    29101 cagcctagag gtgactatgg aacttaatac acacaatgct gaaatcttgc tcagtgcagc
    29161 taataagtcc cactatccgc aggatgaact gccagagatt gccctagcag ggcgttcaaa
    29221 tgttggtaaa tccagcttta tcaacactat gttgaaccgt aagaatctcg cccgtacatc
    29281 aggaaaacct ggtaaaaccc agctcctgaa cttttttaac attgatgaca agatgcgctt
    29341 tgtggatgtg cctggttatg gctatgctcg tgtttctaaa aaggaacgtg aaaagtgggg
    29401 gtgcatgatt gaggagtact taacgactcg ggaaaatctc cgtgcggttg tcagtctagt
    29461 tgaccttcgt catgacccgt cagcagatga tgtgcagatg tacgaatttc tcaagtatta
    29521 tgagattcca gtcatcattg tggcgaccaa ggcggacaag attcctcgtg gtaaatggaa
    29581 caagcatgaa tcagcaatca aaaagaaatt aaactttgac ccgagtgacg atttcatcct
    29641 cttttcatct gtcagcaagg cagggatgga tgaggcttgg gatgcaatct tagaaaaatt
    29701 gtgaggaaaa gaaaatggca aaaacaattc atacagataa ggccccaaag gctatcggac
    29761 cctatgttca aggaaaaatc gttggcaacc ttttgtttgc tagcggtcaa gttcccctat
    29821 cccctgaaac tggggaaatt gtaggagaga atatccaaga acagacagag caagtcttga
    29881 aaaacatcgg tgctattttg gcagaagcag gaacagactt tgaccatgtt gtcaaaacaa
    29941 cttgtttctt gagcgatatg aacgactttg ttccttttaa tgaggtttac caaacggcct
    30001 tcaaagagga attcccagct cgttcagctg tggaggtagc tcgtcttcct cgtgatgtaa
    30061 aagtcgaaat tgaagtcatc gcagagattg gataagctag ttgaagtttg gtgttgccaa
    30121 acttcttttg atataaggag aaaaagatga caaagaaaca acttcacttg gtgattgtga
    30181 cagggatgag tggcgcaggg aaaactgtag ccattcagtc cttcgaggat ctaggttatt
    30241 tcaccattga taatatgccg ccagctctct tgcctaagtt tttgcagctg gttgaaatta
    30301 aggaagacaa tcctaagttg gccttggtag tggatatgcg tagccgttct ttcttttcag
    30361 agattcaagc tgttttggat gagttggaaa atcaagatgg tttggatttc aaaatcctct
    30421 ttttggatgc ggctgataag gaattggtcg ctcgttacaa ggaaaccaga cggagtcacc
    30481 cactagcagc agacggtcgt attttagatg gaatcaagtt ggaacgtgaa ctcttggcac
    30541 ctttgaaaaa tatgagccaa aatgtggtgg atacgactga actcactcca cgtgagctgc
    30601 gcaaaaccct tgcagagcag ttttcagacc aagaacaagc ccagtctttc cgtatcgaag
    30661 tcatgtcttt cggatttaag tatggaatcc cgattgatgc ggacttggtc tttgatgtcc
    30721 gtttcttgcc aaatccctat tatttaccag aactgagaaa ccaaacgggt gtggatgaac
    30781 ctgtttatga ttatgtcatg aaccatcctg agtcagaaga cttttatcaa catttattgg
    30841 ccttgattga gccgattctg ccaagttacc aaaaggaagg taagtccgtt ttgaccattg
    30901 ccatgggatg tacgggtgga caacaccgta gtgtggcatt tgctaaacgc ttggtgcagg
    30961 acttatccaa gaattggtct gttaatgaag ggcatcgcga caaagaccgc agaaaggaaa
    31021 cggtaaaccg ttcatgagaa aaccaaagat aacggtgatt ggtggaggga ctggaattcc
    31081 cgtcattcta aaaagtctgc gggaaaaaga tgtggaaatc gcagctatcg tgacggtggc
    31141 agatgatggt ggttcttcag gtgaactccg aaaaaatatg caacagttga caccgccagg
    31201 tgattttcgt aatgtccttg tggccatgtc ggatatgcct aagttttatg agaaggtctt
    31261 tcagtatcgg ttctctgagg atgccggagc ctttgctggc catccattgg gaaatctcat
    31321 cattgctggc ttgtcagaaa tgcagggttc aacctataat gccatgcagt tattgagcaa
    31381 atttttccat acaacaggga aaatttatcc ttccagtgac catcctttga cccttcatgc
    31441 agtctttcag gatgggacag aagtggctgg agagagtcat attgtagacc atcgaggcat
    31501 aattgacaat gtctatgtga ccaatgccct aaacgatgat acgcctctgg ccagccgtcg
    31561 agtagtgcag accatccttg aaagtgacat gattgtccta gggccaggtt ccctctttac
    31621 ctctattttg cccaatatcg tgattaagga aattgggcgg gctcttttgg aaaccaaggc
    31681 agaaattgcc tatgtctgca atatcatgac ccaacgtggg gagacggaac actttacaga
    31741 tagcgaccac gtggaagtct tgcatcgtca ccttggtcgc ccttttatcg acactgtctt
    31801 ggtgaatatt gaaaaagtgc ctcaggaata catgaattcc aaccgttttg atgaatactt
    31861 ggtgcaagtg gaacacgatt ttgtaggtct ttgtaagcaa gtttcgcgcg tgatttcatc
    31921 taacttcctt cgtctggaaa atggcggtgc cttccacgat ggagatttga ttgtggacga
    31981 gttgatgcgc attatacagg tgaaaaaatg agtttcacag tagcagtaaa agaagaaatc
    32041 ctgggccaac accatctgag ctggcatgaa ttatctgcca ttatcaaaat gtctggtagc
    32101 atcggtctct cgacttcggg cttgactttg tcagttgtga cagaaaatgc caaactggcc
    32161 cgtcacctct atgagtcctt tctccatttc tatgaaatca aatctgaaat tcgtcaccac
    32221 caacggagca atcttcgcaa gaatcgcgtc tataccgttt ttacagatga aaaggtgcag
    32281 gatttgttaa gtgatttgca cttggcagac tctttctttg gcctggaaac aggtattgat
    32341 gaggcgattt tatcggatga ggaagcaggt cgtgcctatc tctgtggcgc tttcttggca
    32401 aatgggagca ttcgtgaccc tgagtcaggc aagtaccagt tggaaatcag ttctgtttat
    32461 ctggaccacg cgcaaggaat tgcctccctt ctccaacagt ttttactgga tgccaaggtg
    32521 cttgagcgca agaagggggc tgtgacctat ctccagcgag cagaagacat tatggacttc
    32581 ttgatagtaa tcggagccat gcaggcacgt gatgattttg agcgggttaa gattttgcga
    32641 gaaacccgta acgacctcaa tcgggctaat aatgccgaga cagctaatat cgctcggaca
    32701 gtttctgcca gcatgaagac cattaacaat atcagtaaaa tcaaagatat catgggctta
    32761 gaaaatttgc cagtagattt gcaggaagtg gcgcaactga ggattcagca cccagactac
    32821 tctatccagc agttagcaga tagtctcagc acccctctga ccaaaagtgg tgtcaatcac
    32881 agactcagaa aaatcaataa gatagcggat gaattataaa accacgaatc ctatgtgact
    32941 cgtggttctt ttttataaac tggtagagtg ttttggttgt actttttgtt cagggtaaat
    33001 gtagttgata gcgttgttga cagcagttgg agcttctccg aggcctgtcg caatcagatc
    33061 aatttttccg tcatagtagc agcagtcacc gatagcatag atacctgctt ggctggattc
    33121 ctgtttgctg tttacgataa tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt
    33181 accgacagaa gatttgaaac catagttgac aaagaggtgg tctaggtcaa tggtttcagt
    33241 ttcatcagat ttgacttttg tgatttcaag tttatcaagt gtttttccat ttccaaggag
    33301 ttggctaggg gcgaatggtg tcttgatggt tacagatgat tcttgcaagg cttgaacact
    33361 gtgttccaag gcacggaaat tatctctgcg gtgaacaagg gtagttggtg cgattttttc
    33421 aaaagccaaa gtccaatcca cagccgagtc tcccccgcca agaatcgtca ctttcttacc
    33481 agcgtattgc tgaatgttag aaacgtggta gtggatattt tcatagccct caaccccttc
    33541 aagttccagc ggacgtggtt tgaaggcacc gccacccata gcaatgataa ctgttttagt
    33601 caggtgactt cctttagaag ttgtgatggc aaattcttct tcttgtttgt caatttcaag
    33661 aaccgtttca ttgagatgaa taggggtatc aaatccattt agctgttcaa tcaagcggtt
    33721 agtcaactct tctccagtca ggtttgggaa gcctggtacg tctaggattt ccttttcagg
    33781 gtagagaata gcaggttgtc cacctagctg gggaagagag tcgatgattt gaaccttggc
    33841 ttggcgtagg tgggcataaa aggctgcaaa aagcccgaca ggaccaccac ccacaatggt
    33901 aatatcatag agttgagaca tagtttctcc tttgtttttt ctagtcagtt tattttatca
    33961 tatttttgtt caatgtaaaa tggactagga tagggaaaaa aatgccagaa aatggtataa
    34021 taggacgaaa gtgttttgat agggaggata tcagggatga attttcaaca attatccaat
    34081 ctgcaatatt ggaccagttt gtttgcaagt ccatggacga tagctatcaa tctgattgat
    34141 attttgattg ttgcttatat tttataccat tttacaaaag ctattgcagg aaccaagatt
    34201 atgattttgg tacgtggagt tttggtgttt attttagctc aaatccttgc aaatatgatt
    34261 ggtttgacta cgatttcttg gttaatcaat caaattatta cttatggggt tattgcggcg
    34321 gttgttatct tctctccaga gattcggact ggtttggaac gtttgggaag agcgacagat
    34381 ttcttttcca atgcccctat tagtgctgag gaacagatga ttcgtgcctt tgttaagtct
    34441 gttgaataca tgagtcctcg taaaatcggg gccttggttg ctattcagcg tgtacgtacc
    34501 ttgcaggagt atatgtcgac aggaattccc ttggatgcta agatttctgc agaacttctc
    34561 attaacattt ttattcccaa cactccccta catgacggtg cggtgattat caaagaagaa
    34621 cgtatcgctg tgacgtctgc ctatctgccc ttgacaaaaa acacagggat ttccaaggaa
    34681 tttgggacca gacaccgggc ggctatcggt ttatcagaag tctcagatgc cttgactttt
    34741 gtcgtatcag aggaaacggg aggaatttcg ataacctata atggaaggtt taagcacaac
    34801 ctaacacttg atgaatttga aacagaatta cgtgaaatct tacttccaaa agaggaagtg
    34861 ggtcttagtt ttaaagaacg attgctagga ggatggaaac atgaaaaaaa atagtttata
    34921 tatcatatcc tcactctttt ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt
    34981 tcaaaacagt accagtgcta ggcaggtaaa aacggaaacc tatactaata cagtaacaaa
    35041 tgtccctatt gacatacgct ataatagtga taagtatttt attagcggtt ttgcttcaga
    35101 agtatcagtg gtcttgactg gtgcaaatcg tctatcgcta gctagtgaaa tgcaagaaag
    35161 tacacgtaaa ttcaaggtta ctgctgacct aacagatgcc ggtgttggaa cgattgaagt
    35221 tcctttgagc attgaagatt tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat
    35281 tacagtcaag attggtaaga aggctcagaa ggataaggta aagattgtac cagagattga
    35341 ccctagtcaa attgatagtc gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt
    35401 gtctattacg agtgaccaag agacattgga tagaattgat aagattatcg ctgtcttgcc
    35461 aactagcgaa cgtataacag gtaattacag tggttcagta cctttgcagg caatcgaccg
    35521 caatggtgtt gtcttaccgg cagttatcac tccgtttgat acaataatga aggtgactac
    35581 aaaaccagta gcaccaagtt caagcacatc aaattcaagt acaagcagtt catcggagac
    35641 atcttcgtca acgaaagcaa ctagttcaaa aacgaattaa aaatagaaaa ggattttata
    35701 acaatgggta aatattttgg gactgatgga gtccgtggag aagctaacct agaactaaca
    35761 ccagaattag cctttaaact aggacgtttt ggaggctatg ttcttagtca acatgaaacg
    35821 gaagcgccga aagtctttgt aggacgtgac acacgtattt caggggaaat gctggaatcg
    35881 gccttggtgg caggtctcct ttcagtaggg attcacgtat acaaacttgg tgtccttgca
    35941 acaccagcag tagcttactt ggttgaaact gaaggagcaa gtgccggtgt catgatttct
    36001 gctagccaca acccagccct tgataacgga atcaagttct ttggcggtga tggcttcaaa
    36061 ctagatgatg aaaaagaagc agaaattgaa gccttgctag atgctgagga agacactctt
    36121 cctcgtccaa gtgcagaagg tttaggaatt ttggtagatt atccagaagg cttgcgtaag
    36181 tatgaaggat accttgtttc aactggaact cctcttgatg gaatgaaggt tgccttggat
    36241 acagctaatg gagcagcttc taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa
    36301 ttgacggtta tcggggaaac accagacggt cttaacatca accttaatgt tggttcaaca
    36361 catccagaag cccttcaaga agtggtcaaa gaaagtgggt cagctattgg tttggccttt
    36421 gatggagaca gtgaccgctt gattgctgtt gatgagaatg gtgacatcgt cgatggtgac
    36481 aagattatgt acatcatcgg aaaatacctt tctgaaaaag gacaattggc tcaaaataca
    36541 attgtgacaa ctgttatgtc taaccttggt ttccacaagg ccttgaatcg cgaaggtatt
    36601 aacaaggcag ttactgcagt tggtgaccgc tacgttgttg aagaaatgag aaaatcaggt
    36661 tacaaccttg gtggtgaaca gtctggtcac gttatcttga tggattacaa taccacaggt
    36721 gatggtcaat tatcagcagt tcaattgact aaaatcatga aggaaactgg taagagctta
    36781 tcagagttgg cggcagaagt aacgatttat ccacaaaaat tagttaatat ccgagtggaa
    36841 aacgtcatga aggaaaaggc catggaagtg ccagctatca aggccatcat cgagaagatg
    36901 gaagaagaaa tggcggggaa cggccgtatc cttgttcgtc caagtggaac agaacccctc
    36961 ttgcgtgtta tggcagaagc gcctacaaca gaagaagtag actactatgt tgataccatc
    37021 acagatgtag ttcgtgctga aattgggatt gactaaatcc tagaaaacta gatgaaaata
    37081 aaaaattatg gtacaatagc ttataatatt gtagccgatg gagaaagaca tgaatcttaa
    37141 acgtgaacaa gaatttgtta gtcagtatca ttttgatgcg cgtaattttg aatgggaaaa
    37201 tgaaaatgga gctcctgaaa ccaaggtgga tgtgaatttc caattgctcc aacatgacca
    37261 agaaaatcaa gtgacttcct tgattgtcat cttgagcttt atgattgtat ttgataagtt
    37321 tgtcattagt ggaacaatct cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc
    37381 aagtgaattg aaccaagaag aggtggaaac cttggctcgt ccatgtttga acatgctcaa
    37441 tcgtttgact tacgaagtga ctgaaattgc attagactta ccaggaatta atttggagtt
    37501 ctaatatgaa attagctgtt ttcacagatt cctctgctta tctcagtgca gagaccttgc
    37561 aaagagaaga cttgtttgtc ttggatattc ctgtcaatat tgatggtgag gaatatgtcg
    37621 aaggcatcaa tctgtctgct gaggaatttt accaaaaaat ggctcaggct tctgaattgc
    37681 ctaagaccag tcaaccaagt attgccaagt tagatgaaat cttaacttcg ctcaaagaac
    37741 aaggctatac acatgccttg gggcttttcc tatcttctgg aatttcaggt ttttaccaaa
    37801 atatccagta tatggtcgat gactatgagg gcttaaccat tgctttccca gacactttga
    37861 ttacaagtgc tcccctaggc atcatggttg aaagcgtctt taattggcgt gatcagggcg
    37921 atgattttgc cagcattcag gataagctag ccattcaaat cagccgtacg tcagccttta
    37981 tcatggtaga tgacttggat catttggtaa aaggtggacg cctttcaaat ggggctgcca
    38041 ttttgggcaa tttgcttagc attaagccaa tcctttattt taacgatcaa ggtgtgattg
    38101 aagtttacga aaaagttcgt actgaaaaga aggccaccaa acgcttaatt gaaattatca
    38161 aggaaacaac ggcttcaggt caataccggg tcattgtcat tcatgggaat gctcctgaaa
    38221 aggctgaaga attgcgtcag catttgcttg attttggctt gggttcggat gtttcacttg
    38281 ctacatttgg tagtgtcatt ggaacgcacc taggagcagg aagtattgct ctgggttata
    38341 ttccagtgat ttagtaggca cttctaggct agttaatctt agcaattgaa cacggactac
    38401 ctgcctcttg aaaaaagatg tctgtcttgc ctttcgtgga aagtcagtgc cattccctat
    38461 ttttcatggg tggctaagat cctttgtatc ttgataattg aacacgcctg gaaccctgtg
    38521 tgaaaaagat agttcttcca aggagtagac acttcttgat cagaattcct attttcactt
    38581 tgtgttctta caggctttgt atcttagaca ggagtagaga tgagtattcg agtaattatt
    38641 gccggtttta agggaaagat gggtcaagct gcttgccaga tggtcttgac tgattcagat
    38701 ttggacttgg tagcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct
    38761 gttttcaagg ataaggctga tttagctggt tttgaagcgg atgtctgggt agactttact
    38821 actccagctg ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta
    38881 gttggaacga ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc
    38941 caagacttgg gtggcctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa
    39001 tttgcgacgc aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac
    39061 aagaaaaagg atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt
    39121 cgagagtcaa ttcagcaagg tgcagcagat gaggaagagc tgattgctgg tgctcgtggt
    39181 gctgactttg atggtatgcg catccactca gttcgtttgc caggtttggt agcccatcag
    39241 gaagtcatct ttggcaatca aggagaagga ttgaccctcc gtcatgactc ctatgatcgc
    39301 atctccttca tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt
    39361 gtctatggat tagaacactt attatgagat taacgcaaat gccttctgaa tttcagaagg
    39421 ctttaccagt attagaaaaa attaaagaag caggctttga ggcttatttt gttgggggct
    39481 ctgttcgaga tgcccttctc catagcccta tccacgatgt ggatattgcg acgtcttctt
    39541 atccagaaga gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa
    39601 ccgtcttggt cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg
    39661 tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt gcgctcgcta gaagaagacc
    39721 tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg
    39781 acttgttcca tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta
    39841 gtgagcgttt caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc
    39901 ttggttttgc acttgagcca gaaacattta aagctatgaa gaccttgacg ccgcttttgg
    39961 agaaaatttc tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt
    40021 ggagaagggg cttggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg
    40081 catctagcca gaacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat
    40141 cctctgaaca agcctgggcg gctttactat gggctttgga gattgaaaat gcgcagtcat
    40201 ttttgaaatc ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta
    40261 ttttggctct gcgtgaaaat ggagaattga gcaagcgaga ttgttatcgc tttgacatag
    40321 atttgctttt acaggctgaa aatcttcgtc aagctcgagg aaaagaagtc aacccacaag
    40381 ccatcacaga aaaataccaa agcttgacta tccatgacaa gaaagatatt cagattaatg
    40441 gcgatatttt gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa
    40501 cagagattga gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg
    40561 cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg
    40621 tgacaagacc gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt
    40681 aatcggtgtc aatgggactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg
    40741 ctttgatggg gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac
    40801 tcaggatcct gattttgatg atagaaagac agttttggat acggttctat ctagtgaact
    40861 caaggaaatc cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa
    40921 gcaggcgcgt ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaatcga
    40981 gagtcaggtc aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg
    41041 ggaattgtca ggtggtctga gaagacgggt acagttggca caagtcttac ttggtaacca
    41101 cgacctcttg cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct
    41161 gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt
    41221 cttagacgct ttgtcaacac ggattttcga gttggatcgt gcaggcttga ccgagtaccg
    41281 gggaaattac caggactatg ttcgcctaaa ggcggaacag gatgagcgcg acgcggctct
    41341 tcttcacaaa aaagaacaac tctacaaaca agaattggcc tggatgcgca gacaaccgca
    41401 ggcgcgtgcg accaagcagc aggcccgtat caatcgattc catgatctga aaaaggaagt
    41461 ttcaggcagt agtgctgaga cagacttgac catgaacttt gaaaccagtc ggattgggaa
    41521 gaaagtcatc gagtttcagg ctgtttcctt tgcctatgaa aacaagccta ttttgcaaga
    41581 ttttaatctc ttggtgcagg ccaaagaccg tatcggaatc gttggggaca atggtgttgg
    41641 aaaatcaacc ctgctcaact tgattgcagg aagtcttgag ccaactaaag gacaagttgt
    41701 gattggggaa actgttcgca tcgcctattt ctctcagcaa attgagggtt tggatgaaag
    41761 caagagagtt atcaattacc tgcaggaagt ggcagaagag gtcaagacca gtggcggttc
    41821 tacgacttcg attgcagagt tgctggagca gttccttttc ccacgttcga cgcatggaac
    41881 cttgattgag aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt
    41941 ggaaaaacca aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt
    42001 gacagtctta gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga
    42061 ccgctatttc ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg
    42121 tcctttcttt ggtcattaca ccgactatct tgatgaaaaa gcttttgaaa cagatatggc
    42181 caatcaagtg caaaaggccg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg
    42241 catgacctac caagaaaagc aggagtgggc aagtattgaa ggtgatattg aagccttgga
    42301 aaaacgtatc gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct
    42361 ggctactctc caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg
    42421 ctatgagtat ctcagtgaat ttgatagttg atactattcg aaaatcaaag tgcaaactat
    42481 gtcggcttca cattgccgac tcaagtacag cctgtgaccg gcttcctaat ttgcactttg
    42541 atttttattg agtataaacg aatagaaaaa tcccgtctca tgaaaggatt tctctattct
    42601 tttttggttt cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta
    42661 tggatgatac catctaactc atagcagata agtttggttt tttgactgat ggaagtaatt
    42721 tgaatgtcct tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc
    42781 tgctctccat cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt
    42841 ccttggtcga tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca
    42901 tcctcaggga taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgattc
    42961 tccagcatag actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga
    43021 ttcatctcta gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat
    43081 ttgaccttgc tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg
    43141 tcgtcaaagc catctgaaag actaaaggaa gactcgatga agatatcata ggcagtcttc
    43201 aagataaaga aagtgatgat gatagcaacc agtttatcca caatcggata attgaaacta
    43261 ctagctagga tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta
    43321 gcagctgcct tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag
    43381 accacaaaca taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc
    43441 gtttcttccc gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag
    43501 aacatgatga tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg
    43561 tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc cacatttcca
    43621 atgatgtccg atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga
    43681 ccagctgcta atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca
    43741 cgctcagcta acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat
    43801 agcattctac cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt
    43861 tgaaaactcc ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct
    43921 gtgatagtgt cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa
    43981 acagcgagac ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag
    44041 aaagagagtc tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac
    44101 gccaagcgtt ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc
    44161 aaggtttgtc atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg
    44221 aagaaggcga gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga
    44281 ttatcatcct agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg
    44341 cagatgccat tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag
    44401 aaggaaaagc tgaagaagct attgaagccc tcaaatccat gtctagtcca gttgcccgcg
    44461 ttcttcgtga tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg
    44521 ttgcccttga agcaggtgac gtggtaccag cggacctacg tttgatagaa gccaactctc
    44581 ttaaaattga agaagcagcc ttgacaggtg aatctgtacc agtcgaaaaa gacttgtcag
    44641 tcgagcttgc gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa
    44701 acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac aggtatgtac actgaagttg
    44761 gtcatattgc tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaatt
    44821 tgaacaacct ttctaaggtc ttgacctatg ctatcttggt cattgccctt gttacttttg
    44881 tagtgggtgt cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc
    44941 ttgccgttgc agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg
    45001 gtactcaagt tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac
    45061 ttggttcaac tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga
    45121 cagtcgaaaa agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag
    45181 gtcttgaaat gccactactt cgttcagttg tcttggccaa tgatacgaaa atcgatgtgg
    45241 aaggtaactt gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg
    45301 gctatgatgt caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact
    45361 ctgaccgtaa gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag
    45421 tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctggggata
    45481 ttactccgat tgatgagaag gttacaaatc tcattcatac aaacaattct gaaatggctc
    45541 atcaagcctt gcgtgtcctt gcaggtgctt ataagattat cgatagtatt ccagaaaatc
    45601 tcacttctga agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgacc
    45661 ctgaacgtcc tgaagccgct gaggctgttc gtgtggctaa ggaagcggga atccgtccaa
    45721 ttatgattac aggtgaccac caagacacag cggaagccat tgccaaacgt ttgggaatca
    45781 ttgacgcaaa cgatacagaa ggtcacgttt taactggtgc tgaactcaat gaactgtcag
    45841 atgaagaatt tgaaaaagtc gttggtcaat actctgttta tgcccgtgtg tctccagaac
    45901 acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa agtcgttgcc atgacaggtg
    45961 acggtgtcaa tgacgcgcca gctctgaaaa cagccgatat cggtatcggt atgggaatca
    46021 ctggtacaga ggtttctaag ggggcttctg atatgattct tgcagatgat aactttgcga
    46081 ctattatcgt cgcagtggaa gaaggacgta aggtcttctc aaacattcaa aagactattc
    46141 agtacctact ttctgctaat actgctgaag tattaaccat cttcctatca accttgtttg
    46201 gttgggatgt cttacagccg gttcatcttt tgtggatcaa cttggtaacg gataccttcc
    46261 cagctatcgc tcttggtgtt gaacctgcgg aacctggtgt catgaatcat aaaccacgtg
    46321 gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac
    46381 tccaagcagc tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg
    46441 gtgacaatca tgctattcat gcagatgccc taacgatggc ctttgcaacc cttggtttga
    46501 ttcagctctt ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc
    46561 cattcaagtc taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa
    46621 caatcgttgt agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat
    46681 ggggaattgt tatggctgga agcttctcaa tgattatcat cgtcgaaatc gttaagttta
    46741 ttcaacgcaa actcggtttt gacaagaatg cgatttaagg gaggtttcgg atgtcagcat
    46801 atcaattacc gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa
    46861 acagaccaac agcaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc
    46921 agctttattc actgggaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac
    46981 tagaagctgg ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg
    47041 atcaattcgg ctcagacttt gtgaagctca atccaaattc caagattcca gccttattgg
    47101 accagtcagg tactgaaaac gtaagagtct ttgagtctgc tcatattctt ctttaccttg
    47161 ctgagaaatt tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt
    47221 ggctattctg gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca
    47281 attatgctcc tgaaaaattg gaatatccta ttaaccgttt tacgatggaa gtgaaacgcc
    47341 agttggattt attggataag gaattggctc agaaacctta tattgcaggc aatgactata
    47401 cgattgcaga tattgctatc tggtcttggt atggacagtt agttcaagga aatctttacc
    47461 aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa
    47521 aaattgccaa tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat
    47581 agcaaaaaag tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta
    47641 tcggcttttg tgctataatt gctataatat agtaaaaagc aagaggagtg tgaggaagtg
    47701 gaaaagaaaa ttgtgaagga tatcttattt ttatctcaag tgtctcagcc ggcaagtcag
    47761 gaggaccttt atcttgccag agatttgcag gatacactct tagcaaatcg tgatacctgt
    47821 gttggtctag ctgccaatat gattggggtg cagaagcgcg tgattatctt taatcttggc
    47881 ttggttcccg tggtcatgtt taacccagtg cttctgtcct ttgaaggatc ctatgaggca
    47941 gaagaaggct gtttgtcctt ggtaggtgtg agatcaacta agcgttatga aaccataagg
    48001 gttgcctatc gtgacagcaa gtggcaggaa cagaccatta ccttgacagg cttcccagct
    48061 cagatttgcc agcatgagct ggatcacttg gaaggacgaa tcatttagga ggaaagcaaa
    48121 tgaaacgaat agtctttgaa cttattttta tcgcaacgac ctggtatatc tttttaccgc
    48181 cccttaacct gaccagctgg gaatttctct tcttcctctg tgggcatttg ttagttgtgg
    48241 caatcttatt tggctttggc aaggggataa accttgtcaa aacggttcat gtgcgccacg
    48301 gtaaggcgga agctgcctta aatcttgagg gtttcaaaat caatcggtta gggaaaattc
    48361 tgttagcttc gattggagga attcttctct tggcagcttt ggtttccttg gtaacttcca
    48421 gcatgtttca ggctaaaaat tatgccaatg tagtcacggt tacggaaaaa gactttactg
    48481 aatttcctaa gagtgacacc agtaaggttc ctatcctaga tagaagtact gctgaaaaaa
    48541 ttggagaccg ctacttgggt tccctaaccg ataaggtgtc gcaatacgta gcggcagata
    48601 cctataccca attgacaatt gatgggaaac cttatcgggt cacaccacta gaatatgcag
    48661 accctatcaa atggtttaac aatcaagcca agggaatcgg tgagtatatc aaggtagaca
    48721 tggtaactgg aaatgcggat ttggtggact tgaagacacc aatcaagtat tcagactcgg
    48781 agtattttaa ccgtgatgtc aaacgtcacc tgcgcttgaa gtacccgacc aaaatcttta
    48841 aaactccatc ttttgaggtg aacgatgagg gcaatccttt ctatgtagca acggtttacc
    48901 aaaagcaatt tggacttgcg gttcctcgtc ctgcttcagt cattatcttg gatgctacaa
    48961 atggagaaac caaggaatac agcttatcag atgttccaga atgggtggac aggatctatc
    49021 cagcagagga aaccattgag caaatcaact acaacggcaa gtacaaggac ggtttcttga
    49081 atgccatgat ttccaagaaa aacgtgaccc agactaccaa tggctataat tacttgtcta
    49141 tcggtaatga catctatctc tacacaggtg tgacgtcggc taatgcggat gagagtaatc
    49201 ttggtttcat ccttgaaaat atgcgaacag gagaaattac taagtatagc ttggcttctg
    49261 cgacagaaga atcagcccgt gaatcagcag aaggtgctgt tcaggagaaa tcctacaaag
    49321 caaccttccc aatcctcatc aacctcaatg acaagcctct ctacatcatg ggcttaaagg
    49381 acaatgctgg cttggtcaaa gagtacgccc tggtagacgc agtcgagtac caaaatgtta
    49441 tcgttgctac tacagtggaa gagatgctca gcaagtatgc caataaaaac gaccttgaaa
    49501 ttgacaatgc aacgacagaa agcatcaagg gagtagtagc agacctcaaa tcagctgtta
    49561 tcaagggaga cactgtctac ttctttaaag ttgatggcaa gatatacaag gtaaaggctt
    49621 cagtatccga tgaccttcct taccttgaaa atggtaaaac cttcgaaggt caagtaggaa
    49681 aagacaatta tctcaagacc tttaaagtac aataatactc ttcgaaaatc tctagctcta
    49741 tctgcaacct caaaacagtg ttttgagcag cctgcggcta gtttcctagt t
//
LOCUS       DBEJNA010000013        48192 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEJNA010000013 DBEJNA010000000
VERSION     DBEJNA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48192
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.13"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(93..945)
                     /locus_tag="ACL3JB_000842"
                     /pseudo
     CDS             complement(93..945)
                     /locus_tag="ACL3JB_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            936..1001
                     /locus_tag="ACL3JB_000843"
     CDS             936..1001
                     /locus_tag="ACL3JB_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGR0685608.1"
                     /translation="MISKFFPILMLVMDIIIIVGG"
     gene            1105..1974
                     /locus_tag="ACL3JB_000844"
     CDS             1105..1974
                     /locus_tag="ACL3JB_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HGR0685609.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYGDCLVTDS
                     GKDYTVIGKYDNL"
     gene            1961..2683
                     /locus_tag="ACL3JB_000845"
     CDS             1961..2683
                     /locus_tag="ACL3JB_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0685610.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            2680..3210
                     /locus_tag="ACL3JB_000846"
     CDS             2680..3210
                     /locus_tag="ACL3JB_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685611.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            3214..4308
                     /locus_tag="ACL3JB_000847"
     CDS             3214..4308
                     /locus_tag="ACL3JB_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685612.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            4311..4982
                     /locus_tag="ACL3JB_000848"
     CDS             4311..4982
                     /locus_tag="ACL3JB_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685613.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            4984..6012
                     /gene="galE"
                     /locus_tag="ACL3JB_000849"
     CDS             4984..6012
                     /gene="galE"
                     /locus_tag="ACL3JB_000849"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0685614.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFSGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            6036..7280
                     /locus_tag="ACL3JB_000850"
     CDS             6036..7280
                     /locus_tag="ACL3JB_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
                     /protein_id="HGR0685615.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            7282..8493
                     /locus_tag="ACL3JB_000851"
                     /pseudo
     CDS             7282..8493
                     /locus_tag="ACL3JB_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428251.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            9173..9394
                     /locus_tag="ACL3JB_000852"
     CDS             9173..9394
                     /locus_tag="ACL3JB_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685616.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            9840..10164
                     /locus_tag="ACL3JB_000853"
                     /pseudo
     CDS             9840..10164
                     /locus_tag="ACL3JB_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            10292..11521
                     /locus_tag="ACL3JB_000854"
     CDS             10292..11521
                     /locus_tag="ACL3JB_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0685617.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            11541..14237
                     /gene="ppc"
                     /locus_tag="ACL3JB_000855"
     CDS             11541..14237
                     /gene="ppc"
                     /locus_tag="ACL3JB_000855"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0685618.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDCIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    14320..14537
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14650..15654
                     /gene="trpX"
                     /locus_tag="ACL3JB_000856"
     CDS             14650..15654
                     /gene="trpX"
                     /locus_tag="ACL3JB_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0685619.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATSAAQGLASATKDLPVIMAAITDPIGANLVKGLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            15723..16589
                     /locus_tag="ACL3JB_000857"
     CDS             15723..16589
                     /locus_tag="ACL3JB_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685620.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            16586..17344
                     /locus_tag="ACL3JB_000858"
     CDS             16586..17344
                     /locus_tag="ACL3JB_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685621.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            17434..19194
                     /gene="dnaG"
                     /locus_tag="ACL3JB_000859"
     CDS             17434..19194
                     /gene="dnaG"
                     /locus_tag="ACL3JB_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0685622.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            19197..20306
                     /gene="rpoD"
                     /locus_tag="ACL3JB_000860"
     CDS             19197..20306
                     /gene="rpoD"
                     /locus_tag="ACL3JB_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0685623.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            20320..20649
                     /locus_tag="ACL3JB_000861"
     CDS             20320..20649
                     /locus_tag="ACL3JB_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0685624.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            20764..21807
                     /gene="cpoA"
                     /locus_tag="ACL3JB_000862"
     CDS             20764..21807
                     /gene="cpoA"
                     /locus_tag="ACL3JB_000862"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0685625.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            21823..23148
                     /locus_tag="ACL3JB_000863"
     CDS             21823..23148
                     /locus_tag="ACL3JB_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0685626.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            23179..23355
                     /locus_tag="ACL3JB_000864"
     CDS             23179..23355
                     /locus_tag="ACL3JB_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0685627.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            23414..23548
                     /locus_tag="ACL3JB_000865"
     CDS             23414..23548
                     /locus_tag="ACL3JB_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0685628.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            23612..24922
                     /gene="obgE"
                     /locus_tag="ACL3JB_000866"
     CDS             23612..24922
                     /gene="obgE"
                     /locus_tag="ACL3JB_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0685629.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            24932..25090
                     /locus_tag="ACL3JB_000867"
     CDS             24932..25090
                     /locus_tag="ACL3JB_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685630.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            26198..27457
                     /locus_tag="ACL3JB_000868"
     CDS             26198..27457
                     /locus_tag="ACL3JB_000868"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0685631.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            27473..28024
                     /locus_tag="ACL3JB_000869"
     CDS             27473..28024
                     /locus_tag="ACL3JB_000869"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685632.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            28017..29294
                     /gene="spxR"
                     /locus_tag="ACL3JB_000870"
     CDS             28017..29294
                     /gene="spxR"
                     /locus_tag="ACL3JB_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0685633.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATTINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            29310..30170
                     /locus_tag="ACL3JB_000871"
     CDS             29310..30170
                     /locus_tag="ACL3JB_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0685634.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKSGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            30549..31342
                     /locus_tag="ACL3JB_000872"
                     /pseudo
     CDS             30549..31342
                     /locus_tag="ACL3JB_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            31358..31855
                     /locus_tag="ACL3JB_000873"
                     /pseudo
     CDS             31358..31855
                     /locus_tag="ACL3JB_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            32012..32437
                     /gene="lacA"
                     /locus_tag="ACL3JB_000874"
     CDS             32012..32437
                     /gene="lacA"
                     /locus_tag="ACL3JB_000874"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0685635.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            32468..32983
                     /gene="lacB"
                     /locus_tag="ACL3JB_000875"
     CDS             32468..32983
                     /gene="lacB"
                     /locus_tag="ACL3JB_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0685636.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGDYHD"
     gene            32994..33923
                     /locus_tag="ACL3JB_000876"
     CDS             32994..33923
                     /locus_tag="ACL3JB_000876"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0685637.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            33925..34905
                     /gene="lacD"
                     /locus_tag="ACL3JB_000877"
     CDS             33925..34905
                     /gene="lacD"
                     /locus_tag="ACL3JB_000877"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0685638.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            35139..35975
                     /locus_tag="ACL3JB_000878"
     CDS             35139..35975
                     /locus_tag="ACL3JB_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0685639.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            36011..36328
                     /locus_tag="ACL3JB_000879"
     CDS             36011..36328
                     /locus_tag="ACL3JB_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0685640.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVQ"
     gene            36328..38019
                     /locus_tag="ACL3JB_000880"
     CDS             36328..38019
                     /locus_tag="ACL3JB_000880"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0685641.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            38234..39640
                     /gene="lacG"
                     /locus_tag="ACL3JB_000881"
     CDS             38234..39640
                     /gene="lacG"
                     /locus_tag="ACL3JB_000881"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0685642.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            39683..39892
                     /locus_tag="ACL3JB_000882"
     CDS             39683..39892
                     /locus_tag="ACL3JB_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0685643.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEE"
     gene            complement(40003..40764)
                     /locus_tag="ACL3JB_000883"
     CDS             complement(40003..40764)
                     /locus_tag="ACL3JB_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0685644.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(40946..41908)
                     /gene="nrdF"
                     /locus_tag="ACL3JB_000884"
     CDS             complement(40946..41908)
                     /gene="nrdF"
                     /locus_tag="ACL3JB_000884"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0685645.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(42096..44255)
                     /gene="nrdE"
                     /locus_tag="ACL3JB_000885"
     CDS             complement(42096..44255)
                     /gene="nrdE"
                     /locus_tag="ACL3JB_000885"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0685646.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(44336..44554)
                     /gene="nrdH"
                     /locus_tag="ACL3JB_000886"
     CDS             complement(44336..44554)
                     /gene="nrdH"
                     /locus_tag="ACL3JB_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0685647.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            44905..45168
                     /locus_tag="ACL3JB_000887"
     CDS             44905..45168
                     /locus_tag="ACL3JB_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0685648.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            45174..46907
                     /gene="ptsP"
                     /locus_tag="ACL3JB_000888"
     CDS             45174..46907
                     /gene="ptsP"
                     /locus_tag="ACL3JB_000888"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0685649.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKEAGEAYAKQKAEWALLKDAKTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVAYNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            47161..>48192
                     /gene="phtA"
                     /locus_tag="ACL3JB_000889"
     CDS             47161..>48192
                     /gene="phtA"
                     /locus_tag="ACL3JB_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGR0685650.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLAPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDATHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELE"
BASE COUNT        15347 a         7961 c        10053 g        14831 t
ORIGIN      
        1 atctgtctat agttaaaact acaagttcat cggagttgat aaggttttat tgagactctt
       61 gattataaaa cgttagatgg taaggaatca tttcatttat tgtttacaag tttatcaaaa
      121 tggctagtat agtgtaattt taacttgtct tctcctaaaa tatcgagaac ttgtatagct
      181 tgtttcattg tttcaatacc actacttaat tgacgtttaa attcatagta accggttgca
      241 tagagaaaaa ctgtctgttc ataaaagttt aattcattct ctgaacaatc cctttatctc
      301 attaattaaa taagagcaat tagaaaattc ttctttatct atgctgagaa tgaaacaatt
      361 tatagctagc tgagtgacaa tccgcttatt tgttttattt agagatgagt aaatataatt
      421 atttaacatt tctttagtta ataagaagta ggagttgtag ttaattgttc gtacacagtt
      481 acctaataaa ataatctcat aataacccca tttttcaact ttaaagagat aatctgctag
      541 ttgaagtaat tcatcatctg atggaatgat tcttgaatcc attgtgtgta aaatggattt
      601 taccattgtt ttttcaaaag aatctaaagt gtaatttgag gaatccgaaa gtagagattg
      661 tatattattg atgttttgta atgaatattg tttacggata tactgtatta agttggcaaa
      721 tgactcagtt tttgtatagt cttcatcgtg taaaataaga aactcatcca aagtaatgtg
      781 taatttgtct aaaatattga tcagtcggat acatgatatc tctgactctc cacgttcaaa
      841 tcgggatatt tgcgattttg aaagatgctc atcagcaaca gagcatagac tgatttgttt
      901 gcctttacga acttttctaa gtgtgatgcc aagttttgat ttcaaaattt ttcccaattt
      961 tgatgctagt gatggacatt atcattattg ttggtggtta aatcacttag gtgtacacct
     1021 aagtctttag attatctaaa gactatactt actagctaaa acatatttaa gttaaatcgt
     1081 aaaattttag agagtggtga gactttgaaa cataaaaaag tattaattat agggtatggt
     1141 ataatgactc ggggtatatt aaaaatcctg aaacagtcga aaaaatataa tatataccta
     1201 tatagtaggc atctaaattc aacaataaat ggaataatat ttattagaga agatgaatta
     1261 cctgatgcta taaatcaggt tgattttata atcacttgtt ttagtaatca tattgaaacg
     1321 gataatttca ttaatgagtt tttattaaat atacaatcac ttcgtaaaac catagtaatt
     1381 gattttacaa cctccaggat tgattgcgtt gaaaaattta aaaaaactgt tgaaattaaa
     1441 gggggatact atatagaggc tcctttcaca ggaggtaagt taggaagtaa tagtggtcaa
     1501 ctatcaattt ttttacatat tgatgaaggt gtaaactata ataaaaagga gttaatggaa
     1561 ttattaaaat taatttcaaa aaaaatatac ttttttgaaa agagtacgga accaacaaaa
     1621 ttcaagttaa tttataactc gtggggagcg tatttgcttt actctattaa gctattcaac
     1681 cctttacagt atgatttttc accaaagtct ctagaggtag cgaatacaat cgtatgtaat
     1741 gatggttgga tgagtttagt atgcaactcc aaattagaac agatcaatga tcaagatttt
     1801 gatgacatac actttagagt agaatatatg gtaaaagatt tagaatatgc taatttttca
     1861 gtctttcatg atgaagtgaa agaaataaat tatttattac agcaatatgg ggattgctta
     1921 gtaactgata gtggaaaaga ttatacggta ataggaaagt atgataactt ataggaatga
     1981 cttgctgtct aaagaattag atatactaat ttcatttttt aaaaaatgcg aagtaggaaa
     2041 aatttcactc gttattactg gttccttggc aagaggtaat ccaagaatca aggatgggaa
     2101 attagaatcg gatattgata ttctagttat agtagacagt attcagcaat taattagtat
     2161 aaaaaagact ttagagggaa ggtttcactt tgtacataaa atttctttga ttttttgttt
     2221 gaaggaaaga ataaatcgaa gtcgttatcg tggaattatt aatagtatta gaagtgtaga
     2281 taatctttta gtagataatc tgcatataaa aaatcaaata atagaagctt tagactcacc
     2341 taccaatatt gtggagcaga ctcgctctat gattcaggaa ttttgttatt attcatcaaa
     2401 atatttaatt tcaaagaata attatttgga attaaaacta gaaaagtatt ggaaggagat
     2461 tgcaacatta aatcatatcg ataaaaagat aaaacaccta gattttgaaa gaatatttgc
     2521 tgttttaaaa gaacacaaaa tacaaatttt ggattcaagt gaatattttt tccaaaatgt
     2581 aaaaacttct gagaatattt atttagagat gagggattta gtatctttgg aaaatcaagg
     2641 attagacttt gaacattgta ttttgagctt gggggaaaga tgataataaa tacattagga
     2701 ccaactgcaa cagattgttt ttatgcaata aatcgtataa aattaaaagt agatgtgatt
     2761 gtactgtatg atagttttga tagtatagtt aattgctttg ataaattaaa agggcaatat
     2821 atattattac ctgtagcttt cgagagtagt attaaaaatt atagttggaa agatttcaac
     2881 tttgaatatc ataagcggat tgaaattgtg gattcttttc actcttttac taagggaatg
     2941 gttctaatcg agaattgtaa ttataaaatt aatagggcga ttatccaacc tgcaactgag
     3001 attttgatgt taaactattt aaagaaaaaa agtatggatc tgaggataga ttttacccat
     3061 agtaaagtta tggcaaataa aaaatttctg gaagaaggtt atcgtttttc aatagtaagc
     3121 caagaaacga taattaataa tgatgatatt attatttgtg aaactttctc tccagaaatg
     3181 atttggtgct tatatagagt gaaaggatag aaaatgtttt ctgaaattat taagaaatat
     3241 gatattgtta cactgaaaga tagtggtttt ttgagaggtg attggttcat aggttcagcg
     3301 ttaatggctc atgactatga aagccttaag gaagggatat atttctatcc ccaggaaaca
     3361 atttggacaa gaatcttgga tttagaatat ataaatccgt attgggaaat atataatcaa
     3421 acttataatt tcttattagt taataaacaa gattcattag caatgaattt tttaactagt
     3481 cttctaagag aaatagaagt tatttcgtct aaaacattag attttgttgt tattacttca
     3541 aacgaacacc taattaggaa tttaattgat agagactatt atattattac aaaagagatt
     3601 ccatttttta ttgaaaactc aaaagttgga aattatttta aaatttttgt gaaaaatgga
     3661 ggacagttta ttcctataat tgactgtacg gaatttaaga ttcagtctaa gaaatatttt
     3721 gagataaata ttaataaatt ctacctgaaa cttttggatt actttcttca tggagagatt
     3781 ccagaaaaat ttaaattttt tggaaatacc tctaatttca atatagaaag cttgtttcta
     3841 gaatttattg atagccaaga aaatattcga gtagtttcct tgttggattg tcttattcaa
     3901 ttatcctcta aaaatattga aatttcagga aattataaag ggcacacagt gaaaaaaata
     3961 ctaaaaaaat tcgctttata ctcagtaatt accaaacttg atataacgaa agtaaatcat
     4021 ttattgagaa atgattatat ctacttttta atgaaggaaa ttgacaatat tactaaaaaa
     4081 tatccaaagt taattcaaaa gtaccctaga gatatcttga gtgataggta tggaataaca
     4141 aatgaagtat atagatactt aatcggagag aatttacata taaaaattaa tcataaatta
     4201 gatgaggtta gatattttac agatattcca tttattgata cttcactttc tattgaagag
     4261 tttgacaaaa tagtttctaa aatattaaaa attaaagtgg gagggtaact atgataagat
     4321 taccaaataa atttaaaggt aataatataa ctctagaagt taaactaaat aaagcagttg
     4381 atgctagtgt attataccca gatgttaagt ctctagatca agaattgtat cgacaactac
     4441 aatcagtaga atcattctat cttacctttt ctgatatgta ttcagaaatt aatgaaaata
     4501 atgaaatctt atatacagaa ataatcttta agatacctct ttgtattgga gaagattatt
     4561 ttaattttcc ggttgtatca tatgtttcaa atccctattc gttaataaga ggattttatc
     4621 taggttttca taaggaattg gactgtaact atgtatttga tgatgcagag cttcattttt
     4681 ttagggaagg gatttgtgaa tttaacttcg aatttaaaaa tcaaaattca atcattacag
     4741 cagaattacc aagggagtat aactatccct tgatcttgtt taataattcc aatctggtta
     4801 atcaatatgg aaaatatact ttgttagaca tagacaaata taaattagag tctagaaaga
     4861 tttttgaatt tccagaaatt tctatcggta actttcttgg aagtgaagca aaatcaaata
     4921 gggtaatttt tagccaagat aaatttcaaa ttaatggcat aaagaatatg gaggtaaatt
     4981 agcatgaaat cattattaat aacaggtgga gcaggataca taggatcaca tacagttttg
     5041 gacttgttag ataataatta tgaagtaaca atcattgatg atttgagtaa ctctaagaaa
     5101 aaagttattg agtctattaa gcagatatcc aagaagagta gaaatcttca tttttataaa
     5161 attgatttaa aaaatgaaga aaaattggaa aatgttttta agagacataa ttttgatgga
     5221 gtaattcatt tttcagggta taaagctgtt ggagaatccg tggttgaacc attgaagtat
     5281 tatgaaaata atttattatc aactataaat attttaaaac taatgaaaaa atataaggta
     5341 tttaattttg tgtttagttc atcagctact gtatacgaaa gtactcctat catgccattc
     5401 tatgagacta atccattaaa agcttcaaac ccgtatggga gaacaaaaca gtatatagaa
     5461 gtacttttaa atgatttgtt tatttcgaat tcaaattgga aaattgtttg tctgaggtat
     5521 tttaatccat tgggtgcaca tgaaagtggt gatttaggag aggatccaaa tggaattccg
     5581 aataatcttg ttccttacat tacacaagtt gcaattggaa aattaccata tttaaatata
     5641 ttcggagttg attacagtac tcctgatggg acttgtataa gggactatgt tcacgttaac
     5701 gatttagcat acggacacag aaaagcatta gagtatattt ttaatacaga tgaaggttta
     5761 tatgaagtaa tcaatttagg aagtggtgtt ggttttagtg tatttgaaat cctacacagc
     5821 ttagagagtg tcataggctc gtatattcca tataagataa cttcaaggag agcaggagat
     5881 atggacgttt caattgcaga tatttcaaaa gcagaagagc tactgggatg gaagccaagg
     5941 tatgatatta tgaaaatgtg ccaagatacg tggaaatggc aacagaaaca tccaaatgga
     6001 tatgatgact aataattgaa aggattggga ttaacatgca tatagtatta tttagatatt
     6061 ctgcacgggt tgttaaacta aaatatctgt ataacagaaa tgtagtaatt attgcacctg
     6121 aggttcaaag aaaaaaatat gaagattatc tagctgaagg aaataatcta cctaaggtca
     6181 tttttttaga agattttatt ctaccaaata tcatcttaga aattagaagg ataagtcaaa
     6241 atacagaagt tgagagtatt acaaccttga gtgaggaaga catggatata gtaggttttt
     6301 tgaatgatca ttttgtagaa aaaaatactc actctgtgtc taatttatta tttaaagaca
     6361 aatacttcat gcgttcattt ttagttggag tagtaaatca accgtatttt aggcttttag
     6421 aatcagaaaa tgatttacgt gttttttgga ataattgtaa atcttctgct gcaattttaa
     6481 aacctagaaa tgaagcagga agtaatggaa taaaaaaagt ttaccctaac gagaaaattg
     6541 attcagtgta ttttgaaaaa aactatatta tagaggaata cattgatatc gataacatga
     6601 taacatgtga tggttattca attggaagtg agattaagcg attttatgtt cacgaatatg
     6661 aggaactatt gttcaatacc ttaagttcta gtggatatta tcttgtaagg actagttcgt
     6721 tatataatga tagtgaaaaa attgaataca tagaaaaagc attggaagaa tgtcgcaaag
     6781 ttttgaatgt tttttctatc aattctgaaa taaccccttt tcattttgaa tggttccttg
     6841 aattatcaac tggtaaaata gtcttttgtg aagttggaaa aagatttgga gggggagata
     6901 ttccccagtt aattgaggat agtcatggag ttgatgtaat taaagaatat tgggatattt
     6961 tgactaattc acaaggattg aaaaaaataa atttttctaa agtgatttct agacctgcta
     7021 atatctcagc aacgtttgct ttatatagaa agcaaggtaa ggttatcgag gtacctgatg
     7081 aaaaagaatt ggcttgggca aaaaaagtgt acatatttat taaaccaaat acttactata
     7141 aagtatctga aaatgtagtc gaaaattcaa tgttggtcca atttaattgc aaaaatagtt
     7201 gtgaatttga gaaaaggtta gatgaactta agcacatatc acaaaagttt aaatatgtga
     7261 ttactgattc gggagaataa aatgattaga gaagaacatc acaatattct atccattgta
     7321 gctagtagga tgatatctcg aatcggagat atcatgtttg atttcgccaa taataccttt
     7381 cttgctggtc ttaatccaac atctctatca gtggttgcaa tttatcaatc attagaaagt
     7441 atgataggtg ttctatttaa tttatttggt ggagttattg cagatagttt caagcggaaa
     7501 aaaattatta ttactacaaa tatcttatgt ggtattgctt gcataactct ttcatttata
     7561 tcccaagaaa aatggttggt ttatgcgata gtcataacaa atgtcatttt ggcttttatg
     7621 agtgcttttt cagggccatc atacaaagct tttacgaaag aaattgtaaa aaaggacagt
     7681 atatcataac ttaattcatt gctagaaaca acaagtactg tgattaaagt aacaattcct
     7741 atgattgcaa ttttcttata taagttactt ggaatacatg gtgtgttatt actagatgga
     7801 ttatcgtttt taattgctgc ctcactaatt ttcttcatta ctcctgtaaa tgaggaggtg
     7861 gatacaaaag agaatatgac gataagagga atctttgatg atttaaaaat aggatttacg
     7921 tatgtatata gtcataaaca aattctcact ataattgccc tttcagcact tgttaacttt
     7981 ttcctagcag cctataattt gttgctgcca tacagtaatc aaatgtttgg aagtatttca
     8041 agtgggctat atggaacctt tttaacagcc gaagcgattg gtggctttat tggtgcgata
     8101 ttaagtggat ttatcaataa atccttgtca agcaaacgtt taatgctctt tttagcatat
     8161 tcaggtttga tgttaatgct aacagcgccg atctattata tgttccgcaa cgtcattatt
     8221 ttagccttta ctccagcatt atttagtcta tttctttcca tttttaatat ccaatttttc
     8281 tctattgttc aaagagacgt agataatgag tttcttggca gagtatttgg aatcatcttt
     8341 acggtagcta ttctttttat gccactaggt actgtttttt tctcagtagt tttaaatcct
     8401 aacaatactt ttaatttttt tattattggt gtatctatta cgatattatc gctaatattt
     8461 agcacgctat tgaagaggta tgatagaagt tgatagatga taaaaaatag ctgatataga
     8521 gaatttagag cgcctttgga atatattttt ggaatttaat caatcacagt tgaatgtgaa
     8581 gggcaatcct ttttagaaga atacaatcaa gataccatta tgctatttct ttagttcagt
     8641 taaaatattg agaagtatta cttttattga aaaagcatca caaaggactc caattaattt
     8701 ttaatgattt ttctaatcta attttgtggt tattgacaaa taaagtctag ttaattgctt
     8761 tgaaatccat ggagtggtct atatacatct gttaatgcaa cggaaaattt tattgataag
     8821 tagggggtgg ctattattca acttttaggt tctgaaagta agagattcac attagaaata
     8881 tcatgttgac catttttcaa tttgctggtt agtagtaatc tggacatcat taatcccttc
     8941 cttaacaaaa ttatgtgact tttgttaccg gattactgct gattttttaa tagtttataa
     9001 catctttaga cggttaatag attttgaccg tctttcttaa tattgtctta cctataatag
     9061 atatgcttat gagatatgtt taataaatta attttagttc aaaatgtcca gtttggacac
     9121 tttgaatgat ttcttagttt tatatattat acttttctca ggagaaagct agatgtacag
     9181 acgtttgaga gatttgaggg aagatcacga tttgacccaa aaacaaatag ctaaaatact
     9241 ttcgtttaca aactcagctt atgctaaaat tgaacggggt gagcatacgt taacagcaga
     9301 tgtattggta actctctcaa acttttacga tgtcagtaca gactacctat tggaattgac
     9361 agattttcct gataaaattc gctttagaaa ataatctcct caatttcata gagtgtgaaa
     9421 atgaggagat tttttatttg ttctttgaaa attaaatagt ccaaaatggt actttcctca
     9481 tttgtggagc aaatttgaat ggctcgccat gataagagcg attttaaaac catcaataaa
     9541 atagagcgat actttatatg ccatgataca aatgatatac aatgatactt ctgaccgttc
     9601 aggctgccat cgtaaaagag cagcaagtga aattcttatg atgacttcat cagtcatgcc
     9661 acgttaaatg tgtgagtttg ttagagaaac gcaattaatc ctcaaaaggt tccccgaacc
     9721 ttttgagttc cacagacgca tcacgtggag tgtgtaagct tgttgctaaa agcgtaaaaa
     9781 ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatacaatac aataaaacta
     9841 tggatgatga agcaagtaaa caattaagcg atagccgttt caagagcctt gtaggtgttc
     9901 agcgcacgag atgttagctg tgtcaaaaac agcttatcaa cgcaacgtaa acgcgcaaaa
     9961 ggtggacgaa aaaccaaatt aagcctagac gatctcctca tggtaactat tcaatacatg
    10021 cgagaatagc gcacttatga acaaattgcg gctgattttg gcattcacga aagcaactta
    10081 atccgtcgga gccaatgggt tgaagtaact cttgttcaaa atggttttac gatttcaaat
    10141 tctgccctaa ttatgaaaaa cagtaaaatt cgaaggattg taaggtaaga gtttttttct
    10201 ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat ttggaacaga
    10261 tttgtctgta tcctagtaga gtggtgatgc tatgaagatt agtaagaggc acttattaaa
    10321 ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg tggtctattc
    10381 gaccaccagt gctattttaa ttgaagaagg caagagcgcc ttgcagttgg ttcgaaacca
    10441 aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat tgagactaga
    10501 ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc ttttattgtt
    10561 cttggctcgt tttattggta tttccgtaaa cggggcatac ggttggattt cggttgcagg
    10621 aataactatt cagccagctg agtacttaaa aatcattatt atttggtatt tagctcaccg
    10681 attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga ctcaaaatca
    10741 atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga ttggaagttt
    10801 gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct tgattatgta
    10861 tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg tatctgccgc
    10921 ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt caaaaattcc
    10981 agtatttggc tatgtagcca agcgctttag tgcctttttt aatccttttg ccgatcgtgc
    11041 tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggcg gttggtttgg
    11101 tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc atacagactt
    11161 tgtcttttct atcgtgattg aagaatttgg ctttgttggt gccagtctta ttttagctct
    11221 cttgtttttc atgattttgc ggattatctt ggtcggtatt cgagcggaga atcctttcaa
    11281 tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg tcaatatcgg
    11341 agggatttcg ggcttgattc catctacagg agtaaccttc cccttcttat cccagggtgg
    11401 aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg atgccagtga
    11461 aaaacgcgct aagttgtacc gagaattgga aaatcaacca atgaaccttc tgttgaagta
    11521 ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt aataaaagtg
    11581 ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact aaaaatatgc
    11641 ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg caggaagatt
    11701 atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc tatatttcac
    11761 gctatttctc tatcttgcct cttttgatta atatttcaga ggatgtggat ttagcttatg
    11821 aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct acaacgatta
    11881 aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat gttgtccctg
    11941 ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta acaaatcata
    12001 ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat aaagataaat
    12061 ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg attcgtgaga
    12121 aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac agctcctttt
    12181 tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg catggtctga
    12241 atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgac cgtgatggaa
    12301 atccatttgt tacagcaaag accttgaagc agtctgcact cactcagtgt gaagtcatca
    12361 tgaactacta tgataaaaag atttaccaac tttatcgtga attttctctt tcaactagca
    12421 ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat aactcgattt
    12481 accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa attcaggcaa
    12541 ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc gccaatgatt
    12601 tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggt gagtccttga
    12661 tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt tacttagcgt
    12721 caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa ctcttgaaat
    12781 cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt gaccttctct
    12841 tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa aaatcagaat
    12901 tattagcaaa agaattagct atttttaaga cggctcgtgt tttgaaagat aagttgggag
    12961 atgatgtcat ccgtcagacc atcatttcac atgcaaccag cctttctgat atgctagaat
    13021 tagctattct gttaaaagag gtaggactgg tggatacgga aagggcgcgt gttcagattg
    13081 ttcccctttt tgaaacaatt gaagacttgg atcattcaga ggaaacaatg agaaaatatc
    13141 tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa gaaatcatgc
    13201 ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg accctctaca
    13261 aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt accttcttcc
    13321 atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc attacatctc
    13381 aaccgctcaa gtctatcaag gattgtatcc gcttgacgga gcagggtgaa gtaattggga
    13441 ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta tcggcagcta
    13501 ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt tatgaagcca
    13561 ttatggatca agtagtggac cgtagttacg atatctaccg tgatttggtc tttggtaatg
    13621 agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca agttttaata
    13681 ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggtttg cgtgccatcc
    13741 cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac ggggttggtt
    13801 caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta cgagatatgt
    13861 accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt ttgtcaaaat
    13921 caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa gttaaggcca
    13981 tctatgagac tattttaaat gaatggcaag ttactaagaa cgttatcttg gctattgaag
    14041 gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat taccgtatgc
    14101 cttactttaa tattctcaac tatattcagt tagagttgat taaacgccaa cgtcgtggag
    14161 aattgtccag tgatcaagaa cgattgattc atatcaccat caacggaatt gcgacaggat
    14221 tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat caaaaaaatt
    14281 ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca gaaaagtaat
    14341 catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggcg atgatgaaaa
    14401 ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac accttacagt
    14461 gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag gtggtaccgc
    14521 gcatcgacgt ccttacacaa gttttttgtg tgaggatttt tttgatggag gttagtatgg
    14581 aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga aataaaaagg
    14641 agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc agtcttagta
    14701 gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa taaggatgag
    14761 aagaaaataa ccaagattgg tgtgcttcaa tttgtgagcc atccatccct tgatttgatt
    14821 tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca agttaaaatt
    14881 gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa acaattggtt
    14941 gcaaatggga atgaccttgt ggttggtatc gcaacatcag cagcccaagg gttggctagt
    15001 gcaacaaaag acctaccagt tatcatggcc gctattacag acccaattgg tgctaacttg
    15061 gttaaaggtt tgaaaaaacc aggtggcaac gttacagggg tatctgacca caatccagct
    15121 caacaacaaa ttgaactcat caaggctctg acaccgaatg tgaaaacaat cggagctctt
    15181 tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc ttatgctgaa
    15241 aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat tgcctcaact
    15301 gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa caccattgca
    15361 tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat ttatcccagt
    15421 gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca acatgacctt
    15481 ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc agccgatacc
    15541 ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc acaagaacta
    15601 ggtattacta ttcctgagtc tgttctcaaa gaagcaggac aagtcatcga ataaataagg
    15661 tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg attaaataaa
    15721 atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt ctgggaatct
    15781 ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc ttccctcttg
    15841 ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta gcgacacttg
    15901 ttgctgtagg agcaggttgt ttggctggaa tggcagcagg ccttctttat acaaaaggga
    15961 agatcccaac cttgctctca gggattttgg tgatgacttc ttgtcactca atcatgctct
    16021 tgattatggg acgtgcgaat ttaggcctgc ttggaaccaa gcaaattcag gatgttttgc
    16081 cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagt attgttattg
    16141 ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct acaggggata
    16201 atcctgatat ggctagaagt ttcgggattc atactggacg catggagctc atgggcttgg
    16261 tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa gaaggttatg
    16321 ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg attattggag
    16381 aagttatttt caagagtttg agcttggcag agcgtttggt tactatcgtt gtaggttcta
    16441 tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca agttaccttc
    16501 gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt aagcaaacaa
    16561 tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa atgcaaccaa
    16621 aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt ccttagaaat
    16681 ttttgaacgg gactttatca cgattttggg cggaaatggt gctggaaaat caactctctt
    16741 taacactata gcagggacct tatcactaac tagtggaact atccgtattt taggtgaaga
    16801 tctcactaag ttttcacccg agaagcgtgc caagtacctg tctcgtgtct tccaagatcc
    16861 aaagatgggg acagctcccc gtatgacggt cgctgaaaat cttttaatcg ccaagtttcg
    16921 tggtgaaaag cgtggattgt taccacgacg cttgactagc tataaggatg aatttcaggc
    16981 aaccattgaa aaagtaggaa atggtcttga gaaacacttg aatacaccga ttgagttctt
    17041 atcaggtgga caaagacagg ctttgagtct cttgatggca accttgaagc gacctgaatt
    17101 actcctgtta gatgagcata ctgctgccct ggatccaaag actagtgttg ctttgatgga
    17161 attgacagat gaatttgtta agaaagatca gctaacagcc cttatgatta ctcatcatat
    17221 ggaagatgct ctcaaatacg gcaatcgctt gattgtcatg aaagaaggac gaattatcca
    17281 agatttaaac caagaagaaa aagcaaaaat gaaaatctct gattattatc aactctttga
    17341 ataaagtagg gaaaatgagt gaaatggttt actttttttc tgaaataaag tatactatat
    17401 aaagtaaact atgataacat ggaggtattg tgtatggttg acaaacaagt cattgaagaa
    17461 atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt acaaaaggca
    17521 ggacggaact atctagggct ctgtcctttt catggtgaaa aaacaccatc tttcaatgtt
    17581 gtagaggaca agcagtttta tcactgtttc ggttgtggtc gctcaggtga tgtctttaag
    17641 ttcatcgagg agtaccaagg ggttcccttt atagaagcag tccaaatctt aggtcagcgt
    17701 gttggaattg aggttgaaaa accgctttat agtgagcaga agtcagcctc acctcaccaa
    17761 gctctttatg atatgcacga agatgcagcc aaattttacc atgctattct catgacaacg
    17821 actatgggcg aagaggccag aaattacctt tatcagcggg ggttgacaga tgaagtgctt
    17881 aaacattttt ggattggttt agcacctcca gaacgaaact atctctatca acgtttgtct
    17941 gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc ggatgccaat
    18001 caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga ccaaggaaag
    18061 gtcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc taagtataaa
    18121 aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat ggatagggca
    18181 aaaagatctt ctggaaaagc tagtgagatt tacctgatgg aaggattcat ggatgttatt
    18241 gcagcctatc gggctggaat cgaaaatgct gtggcgtcga tgggaacagc cttgagtcga
    18301 gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta cgatggagat
    18361 aaggctgggc aagccgcgac attgaaagca ttggatgaaa ttggtgatat gcctgtgcaa
    18421 atcgtcagca tgcctgataa cttggatcct gatgagtatc tacaaaaaaa tggtccagaa
    18481 gacttggcct atctattaac gaaaactcgt attagtccga ttgagttcta cattcatcag
    18541 tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttcttga aaaaatagct
    18601 cccttgattg ttcaagaaaa gtccatcgct gctcaaaaca gctatattca tattttagct
    18661 gacagtctgg cgtcctttga ttatacccag attgagcaga ttgttaatga gagtcgtcag
    18721 gtgcaaaggc agaatcgcat ggaaggaatt tccagaccga cgccaatcac catgcctgtc
    18781 accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg gatgatggaa
    18841 tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc tacacctgaa
    18901 tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga agttttagca
    18961 gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga tttgcctgct
    19021 gagatatcgc cgcaggaact tagtgaagta gagatgactc gaaacaaggc tctcttgaat
    19081 caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg agatacagat
    19141 acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga gtaataatgg
    19201 caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt atccgtaatc
    19261 ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtctggtt attcctttta
    19321 ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca ggcatttcta
    19381 tcacagataa cgaaggaaat ccaagtgcgc gtgttctcag caatgaagaa gaaccagaac
    19441 tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct gtccgtatgt
    19501 acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa gagttggcac
    19561 tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc aatcttcgtt
    19621 tggttgtttc cattgccaaa cgctatgtcg gtcgtggtat gcagttcctt gacttgattc
    19681 aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct aaagggttca
    19741 agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct attgcggacc
    19801 aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa ttggttcgtg
    19861 aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag attgctgaac
    19921 gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa gaaccagtat
    19981 ctcttgaaac tcctatcggt gaagaggacg atagccacct tggagacttt atcgaagatg
    20041 aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag caattggatg
    20101 aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt tttggactag
    20161 atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta actcgtgagc
    20221 gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt cgtagcaaac
    20281 cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac agaagagcaa
    20341 attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga ccctgagttg
    20401 ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg tgacacaggg
    20461 caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga ccttttgaca
    20521 gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga ggttaaatta
    20581 gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat tgccctaggc
    20641 attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa atttcccctc
    20701 ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga tataatagta
    20761 gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa agtagcagga
    20821 cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc tgccaaggac
    20881 caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt tcatacgatt
    20941 gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa gattggctat
    21001 gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt cttaaaggga
    21061 attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt tgtggtcaat
    21121 cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt gacctatatt
    21181 cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt agtcagactg
    21241 cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg gcaagttcag
    21301 aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca gattaccttt
    21361 atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca ctataagaaa
    21421 attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc agagcggatg
    21481 cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga gctctttcct
    21541 atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga tttagatctc
    21601 tataaggtga ttttggaggg aaattatcgg gcgacagcgg gtagagaaga gatgaaagag
    21661 gctattttgg aatatcaagc aaatcctgct gtcttaaaag atctcaaaga aaaggctaag
    21721 aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga cttttatgag
    21781 aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat tggtttattt
    21841 acagatacct attttcctca ggtttctggt gttgcgacca gtattcgaac cttgaaaaca
    21901 gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa ggatgtcaat
    21961 cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc ttttaaggat
    22021 cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca gtatcagcta
    22081 gatattatcc atactcagac agaattttct cttggcctgt tggggatttg gattgcgcgt
    22141 gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta tgtccattat
    22201 attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag aggtttcctg
    22261 catgatgtgg atggggttat ttgccctagt gagattgtcc gtgacttgct atctgattat
    22321 aaggtcaagg ttgaaaaacg ggtcattcct actgggattg aattagccaa gtttgagcgt
    22381 ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat tcaagatggt
    22441 gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca agcagtttta
    22501 gcagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt agctggggat
    22561 ggcccttatc tgaatgacct caaagagcaa gcccagaacc tagagattca agactcagtc
    22621 atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc ggcggatttc
    22681 ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag cttagccagt
    22741 ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag tgataaaatg
    22801 tttggaacct tgtactatgg agaacatgat ttggctggtg ctattttgga agccctgatt
    22861 gcaacaccag acatgaacga gcatacctta tcagagaaat tgtatgagat ttcagctgag
    22921 aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa taacttccag
    22981 aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt tttgtatctt
    23041 cagcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa ggcttcaaaa
    23101 acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa agaggaacag
    23161 ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg tgtttgtgct
    23221 ggggtggccc attatctgga tatggatccg actatcgttc aagtcatttg gggtgttctt
    23281 acttgctgtt acggagctgg aattgtagct tacattattt tatggattat cgcaccagta
    23341 gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat agaatgtaac
    23401 gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta tgtttgagaa
    23461 aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa tttttgcaac
    23521 tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt gactgggatt
    23581 tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata cagctaagat
    23641 taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg aaaaatatgt
    23701 ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg tcttcgttgt
    23761 agacgaagga ctacgtacct tgatggattt ccgctacaat cgtcatttca aggctgattc
    23821 tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc ttagagttcg
    23881 agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa cagatttgat
    23941 tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg gaaatattcg
    24001 tttcgcgaca ccaaaaaatc ctgcaccgga aatctctgaa aatggagaac caggtcagga
    24061 acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag gattcccatc
    24121 tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa ttggtgccta
    24181 ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag gtgaatcctt
    24241 tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg gtttgggaac
    24301 tcagttcctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg atatgtcagc
    24361 tagcgagggc cgtgatccat atgaggacta cctagctatc aataaagagc tggagtctta
    24421 caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg acatgcctga
    24481 gagtcaggaa aatcttgaag actttaagaa aaaattggct gaaaattatg atgaatttga
    24541 agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg caacactttt
    24601 agatgctaca gctgaattgt tagacaagac accagaattt ttgctctacg acgagtccga
    24661 tatggaagaa gaagcttact atggatttga cgaagaagaa aaagcctttg aaattagtcg
    24721 tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct ttaatatgac
    24781 caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg gtatgggggt
    24841 tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca ttggtaaatt
    24901 tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat ctttccgaga
    24961 tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat tggaagaact
    25021 atttaatcgt ctcaatccaa atcgtgcctt gagattggca cgaactaaaa aggaaaatcc
    25081 atctcagtaa agaagctaaa aaatcccgtg cctcatcaga cacgggattt tgtggtacga
    25141 caggcatgta tagcaaactg aatctggaat agcacagcat atcttctaaa atatagtaaa
    25201 atgaaatgag aacaggacaa atcgatcagg acagtaaaat cgatttctaa caatgtttta
    25261 gaagcagaga tgtactattc tagtttcaat caactatatt gttataaatt gatttgaatt
    25321 tcaaaattaa attgtttgat tcttatttca atttgttata gtatatctga tgtcaaagtt
    25381 ctcggcgagt caaatagcga ttcccaagcc tgactatcgt gaggtagcgg attaaaatgg
    25441 tctggggata gaccgtttta agtctgacgc tggaaataag aattgtcaga agaagggata
    25501 gcgaaatcgt ggctctacga acaggaacgt gataataagg cgtatatagc ggataagagg
    25561 gcctcaaact ctaaagtcca aaaaggtagt cgtaacctat atgcgtaaat cacgagagta
    25621 attgaattcg tactaagatt ttctattttc actgtaacct tttaacgtcc tcgtatcttg
    25681 tatacacgag gaaagatgta cgacttatcc cgtgaggtct atcactataa agagaaaacg
    25741 acagatagaa gtgatcctga gtcacggtta tctttaaaat agattgtctg ataggacggt
    25801 atgtataaaa cgcttctgtg aactgagaga agggggagaa gttcttgcta aaatttagtt
    25861 gaacagccgt attccgatat ttagataagg gatctagtct tagctcctac tcagttttag
    25921 gggataaaaa aggggcaata gcgattcgag aaagattata ctcttcgaaa atctcttcaa
    25981 atcacgtcaa tatcgccttg ccgtatgtgt aggatactga ctacgtcagt tctatctaca
    26041 acctcaaaac agtgttttga gcaacctgcg gctagtttcc tagtttgatc tttgattttc
    26101 atttaaaatt gaaaaggatg gaaaaaagga taaatttatg atatacttta ttttgaagac
    26161 cttattagaa atcttgaaag agtattgaaa acttagaatg agaaaaattg ttatcaatgg
    26221 tggattacca ctgcaaggtg aaatcactat tagtggtgct aaaaatagtg tcgttgcctt
    26281 aattccagct attatcttgg ctgatgatgt ggtgactttg gattgcgttc cagacatttc
    26341 ggatgtagcc agtcttgtcg aaatcatgga attgatggga gctactgtta agcgttatga
    26401 cgatgtattg gagattgacc caagaggtgt tcaaaatatt ccaatgcctt atggtaaaat
    26461 taacagtctt cgtgcatctt actattttta tgggagcctc ttaggccgtt ttggtgaagc
    26521 gacagttggt ctaccgggag gatgtgatct tggtcctcgt ccgattgact tacaccttaa
    26581 ggcgtttgaa gctatgggtg cgactgctag ctacgaggga gataacatga agttatctgc
    26641 taaagataca ggacttcatg gtgcaagtat ttacatggat acggttagtg tgggagcaac
    26701 gattaatacg atgattgctg cggttaaagc aaatggtcgt actattattg aaaatgcagc
    26761 ccgtgaacct gagattattg atgtagctac tctcttgaat aatatgggtg cccatatccg
    26821 tggggcagga actaatatca tcattattga tggtgttgaa agattacatg ggacacgtca
    26881 tcaggtgatt ccagaccgca ttgaagctgg aacatatata tctttagctg ctgcagttgg
    26941 taaaggaatt cgtataaata atgttcttta cgaacacctg gaagggttta ttgctaagtt
    27001 ggaagaaatg ggagtgagaa tgactgtatc tgaagacagc atttttgtcg aggaacagtc
    27061 taatttgaaa gcaatcaata ttaagacagc tccttaccca ggctttgcaa ctgatttgca
    27121 acaaccgctt acccctcttt tactaagagc gaatggtcgt ggtacaattg tcgatacgat
    27181 ttacgaaaaa cgtgtaaatc atgtttttga actagcaaag atggatgcgg atatttcgac
    27241 aacaaatggt catattttgt acacgggtgg acgtgattta cgtggggcca gtgttaaagc
    27301 gaccgactta agagctgggg ctgcactagt cattgctggg cttatggctg aaggtaaaac
    27361 tgaaattacc aatatcgagt ttatcttacg tggttattct gatattatcg aaaaattacg
    27421 taatttagga gcggatatta gacttgttga ggattaaacc gtagaggtgt ttatgaatat
    27481 ttggaccaaa ttagcaatgt tttctttttt tgaaacggat cgcttgtatt tgcgtccttt
    27541 cttttttagt gatagtcagg acttccgcga gatagcttca aatccagaaa atcttcaatt
    27601 tattttccca acgcaggcaa gtctggaaga aagtcaatat gcactggcca attactttat
    27661 gaagtcccct ttgggagtgt gggcaatttg tgaccagaaa aatcaacaaa tgattggttc
    27721 tattaaattt gagaagttag atgaaatcaa aaaagaagct gagcttggct attttttgag
    27781 aaaagatgct tggtcgcaag gatttatgac agaggttgtt agaaaaattt gtcagctttc
    27841 ttttgaggaa tttggcttaa aacaattatc tatcattacc caccttgaaa atgaagctag
    27901 ccaaagagtt gctcttaagt ctggatttag tttgttccgt cagtttaagg gaagtgatcg
    27961 ttacacaaga aaaatgcggg attatcttga atttcggtat gtaaaaggag agttcaatga
    28021 gtaagcatca ggaaattcta agctatttgg aggaattacc agtaggtaaa agggtcagtg
    28081 ttcgtagcat ttcgaatcat ctaggagtta gtgatggaac agcctatcgg gctattaaag
    28141 aagctgaaaa ccgtggaatt gtggagaccc gtcctagaag tggaacaatt cgtgttaaat
    28201 cccagaaagt tgctatagag agattaacgt ttgctgaaat tgcagaagtg acttcttctg
    28261 aggttctggc tgggcaagaa ggtttagaga gagaatttag caagttttca attggtgcca
    28321 tgactgaaca aaatatcttg tcttaccttc atgatggggg gctcttgatt gtcggagacc
    28381 gaacccgtat tcagttgcta gccttggaaa atgaaaatgc agttctggtt acagggggat
    28441 ttcaggttca tgatgatgtg cttaaactgg ccaatcaaaa agggattcct gttctaagaa
    28501 gtaagcatga tacctttacc gtcgcgacca cgatcaataa agccttgtca aatgtccaaa
    28561 tcaagactga tattctgaca gttgagaaac tttatcgccc tagtcatgag tatggttttc
    28621 tgagagagac agatacagtt aaagattatt tggacttggt tcgtaagaat cgtagcagcc
    28681 gtttccctgt tatcaatcaa catcaggtcg ttgttggcgt tgtaaccatg agagacgctg
    28741 gtgataaatc accaagcacg acaattgata aggttatgtc tcgtagtcta tttttggttg
    28801 gattatcgac aaatattgcc aatgtgagtc aacggatgat cgcagaagac tttgaaatgg
    28861 taccagttgt tcgaagcaat caaactttgc ttggcgttgt gacgcgacga gatgtcatgg
    28921 agaagatgag ccgttctcaa gtttcggctc taccaacttt ttctgagcag attggacaaa
    28981 agctctctta tcaccatgat gaagtagtca ttacagtgga accctttatg ctagaaaaaa
    29041 atggagtttt ggctaatggt gtattggcag aaattctgac ccacatgacc caagatttag
    29101 ttgttaatag tggtcgcaat ctcattatcg agcagatgct gatctacttt ttgcaggctg
    29161 ttcagataga tgatatattg cgcattcagg cacggattat tcatcatacg agacggtcag
    29221 ctataattga ttacgatatt tatcatggtc accagattgt ttcaaaagca aatgtgactg
    29281 ttaaaattaa ttagaaacta ggagaaaaga tgataacatt aaaatcagct cgtgaaatcg
    29341 aagctatgga caaggctggt gattttctag caagtattca tataggctta cgtgatttga
    29401 ttaagtcagg cgtagatatg tgggaagttg aagaatatgt ccgccgtcgt tgtaaagaag
    29461 aaaatttcct tccacttcag attggggttg acggtgccat gatggactat ccttatgcta
    29521 cctgttgctc tcttaacgat gaagtggctc acgctttccc tcgtcattat atcttgaaag
    29581 atggtgattt gctcaaagtt gatatggttt tgggaggtcc cattgctaaa tctgacctga
    29641 atgtctcaaa attaaacttc aacaatgttg aacaaatgaa aaaatacact cagagctatt
    29701 ctggtggttt agcagactca tgttgggctt atgctgttgg tacaccgtcc gaagaagtca
    29761 aaaacttgat ggatgtaacc aaagaagcta tgtacaaggg tattgagcaa gctgttattg
    29821 gaaatcgtat cggtgatatc ggtgcggcta ttcaagaata cgctgaaagt cgtggttacg
    29881 gtgtagtgcg tgatttggtt ggtcatggtg ttggcccaac tatgcacgaa gaaccaatgg
    29941 ttcctaacta tggtattgca ggtcgtggac tccgtcttcg tgaaggaatg gtcttaacca
    30001 ttgaaccaat gatcaataca ggcgattggg aaattgatac agatatgaaa actggttggg
    30061 cgcataagac cattgacggt ggattgtcat gtcagtatga acaccaattt gtcattacga
    30121 aagatggacc tgttatcttg actagccaag gtgaagaagg aacttattaa taaaaagtga
    30181 aaagactact ggaagtttat tatgaaaaaa tccagtagat cttttcataa taaaacgcat
    30241 tgtatcaagt gttaggggct gatatcatgc gtttttctgc ttttaagatt ttttccaact
    30301 ctgtttgtaa gcgcatcata acaaagggtc taggattcag ggctctcctc ctatatacta
    30361 ttagtaaagt aaaactaagg gaggatattt tagtgtcgca gtctattgtt cctgtagaga
    30421 ttccacaata ttgtcgtttt gattctaaaa agagaaatgg aattctgttt aatgttcgta
    30481 ttgccaatct taaatttacc ttttttagat tagactccct gcgaaacaaa acatggtata
    30541 gtagttctat gaatgatgaa gcaagtaaac aactaactga tgcacgattt aagcgttttg
    30601 ttggtgttca gcgcacgact tttgaagaga tgttagctgt attaaaaaca gcttatcaac
    30661 ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct agaagacctt cttatggcta
    30721 ctcttcaata tgtgcgagaa tatcgaactt atgaacaaat tgcggctgat tttggtatcc
    30781 acgaaagcaa ctttatccgt cggagccaat gggttgaagt aactcttgtt caaagtggtg
    30841 ttacgatttc aagaactcct ctcagctctg aggacacggt aatgattgat gcgacggaag
    30901 tacaaatcaa tcgccctaaa aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac
    30961 gctatgaagg ctcaagcgat tgtcacaagt caagggagaa ttgtttcttt ggatatcgct
    31021 gtgaactatt tgttatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc
    31081 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
    31141 aactccacgt aaatccagca aactcaagcc gctaacagct gaagataaag cctgtaacca
    31201 tgcgctatcc aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
    31261 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
    31321 tgctggtatt atcggattct agttttgcag gaagtctaat aaagaaacta gcaaggtcag
    31381 gccttacttt attggtggac atccaggatt taattgtctt ctacttgatg atgaagtcta
    31441 tgaagattat tatctagagt ttgagaaaga agagatttgc tctgttccac gtcctttccc
    31501 agaaacaggt atgttggatt tccaagatag aagtccatgg ctagagggac aaaaagaaat
    31561 agatcttagt tatgatcttt tcagcacaga tgcagtgact ttggatgaat tgcaatctcg
    31621 aacaattgcc cttcgttctc ttaaacatga taagggattg aaagtgcatt ttgcagaatt
    31681 tccaaacctc atcatctggt caactttgaa caagggacct ttcattacct ttgaaccatg
    31741 gtctggcttg tcaacattcc ttgaagaagg agatcattta gaagataaga agaatgtttg
    31801 tctcttagaa gccaatcagg ttgaagaatt agggtttgag atagaagttt tataaaaaag
    31861 taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa tagtagtata
    31921 ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact gctggaatcc
    31981 agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg cagatgctgc
    32041 aggtttgaga ttgaaagaag ttgtgaaaga ctttttagaa aaagaaaact tccaccttgt
    32101 ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg ctgcagaagt
    32161 aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg gtccatttat
    32221 ggttgcaact aagatcaaag gaatggttgc tgcagaagta tctgacgaac gttcagctta
    32281 tatgactcgt ggccacaaca actcacgtat gatcactatg ggggcacaac ttgttggtga
    32341 tgaattggct aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg gtggtcgtca
    32401 ccaaatccgg gttgacatgt tgaacaaaat gggctaatta gattatagta agaaaggtaa
    32461 gttaaaaatg agaattgcaa ttggatgtga ccacatcgta actgatgaaa aaatggcggt
    32521 ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacat atgaccatac
    32581 acggactcac tacccaatct ttggtaaaaa agtaggggaa gcagtaacta gtggtcaagc
    32641 tgatctcggg gtatgtatct gtggtactgg tgttggtatc aacaacgctg taaataaagt
    32701 tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg ctaaagaaca
    32761 attgaacgcc aacgttatcg gttttggtgg taagattact ggtgaattgc ttatgtgtga
    32821 tatcatcgaa gctttcattc atgctgaata caaaccatct gaagaaaaca aaaaattgat
    32881 tgcgaaaatt gaacaccttg aaagtcacaa tgctcaacaa acagacgcaa acttcttcac
    32941 tgaattcctt gaaaaatggg atcgcggaga ctaccacgac taagaggtaa actatgattt
    33001 taacagttac aatgaaccca tccattgata tttcctatcc cttggatgag ttgaagattg
    33061 atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga ctcaatgtta
    33121 cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg ggtggcaaac
    33181 ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc ttctcaattc
    33241 agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca gaagttcttg
    33301 aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat ttcaaaaaac
    33361 tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc cttccagttg
    33421 attactatgc gagcttggta gaacttgcta atcaagctgg caagcctgta gtcttggact
    33481 gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca gtcatcaaac
    33541 caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat ttggatgaat
    33601 taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc gtttcacttg
    33661 gtgccaacgg tacttttgcc aaacatggtg acactttcta caaggtagat attcctagaa
    33721 ttcaggtggt aaatcctgtt ggatctggag actctactgt ggcaggaatt tcttcaggac
    33781 ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt ggtatgctca
    33841 atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagtt ctatatgatc
    33901 aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt acgcttagaa
    33961 aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg tggtgctttg
    34021 aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat ggaagaactt
    34081 aaagtcttgg tagcagatga attgactaaa tacgcttcat ctatgcttct tgaccctgag
    34141 tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct tgcttatgaa
    34201 aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga tgtctggtct
    34261 gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta ctatgatgta
    34321 gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat cggttctgag
    34381 tgtgtggctg aagatatccc attcttcctt gaaatccttg cttacgatga aaaaattgcg
    34441 gatgcaggtt ctgtagaata cgcgaaagta aaaccacaca aagttatcgg cgctatgaaa
    34501 gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc tgttaacatt
    34561 aaatatgttg aaggcttcgc tgaaggtgaa gtagtttata cacgtgaaga agcagcagcc
    34621 ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag tgctggtgta
    34681 tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc aaactttaac
    34741 ggagttcttt gtggccgtgc tacatgggca ggatcagttg aagcttacat caaagatggt
    34801 gaagcagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga tgagctcaat
    34861 aaagttcttc aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag tcctcctagt
    34921 ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt acaaaataac
    34981 ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta agtaatatta
    35041 ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt ggtcattttt
    35101 tgtacttata tacctttaag atataaaagg aggttgacat gtatcgaatt ctaaatccaa
    35161 tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt gtaattggta
    35221 agggaattgc attcggaaag aagaaggggg atttgattgc tgaaaatcag gttgagaaaa
    35281 tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc aaagatgttc
    35341 cgcttgattt tatcacagtg acctatgaaa tcattgataa gctatcaaag aaatatcatt
    35401 atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt tcttatcaag
    35461 ctctaactca aggaaggtac aaggatagta atctgccaga tatttccgct aagtatcctg
    35521 tcgcttttca aatcgcaaat gaagcttttg aaatttaccg tcagaagcta gcagatcatt
    35581 ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa ggtgaaaatg
    35641 aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat gttgaagaag
    35701 ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat gatcgcttta
    35761 tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat aaccaatcac
    35821 ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag attggttcca
    35881 agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt gaacgagttt
    35941 atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac tatataagga
    36001 gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg tagcctatgc
    36061 tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg gtgattttga
    36121 aaaagcggac gctctggtag aggaagctgg tagctgtatt gcagaggctc accacgcgca
    36181 aacaagtcta ttgactaagg aagcttcagg tgaggacttg gcttatagtg taaccatgat
    36241 gcatggccaa gaccacttaa tgacaactat cttgttaaaa gatttgatgc atcatttaat
    36301 tgaactctac aagagaggag ttcaataatg aataaactaa ttgcatttat cgagaaagga
    36361 aagcctttct ttgaaaaact atctcgtaat atctatcttc gtgctattcg tgatggtttc
    36421 attgcaggta tgcctgttat tctcttctca agtatcttta tcttgattgc ctttgtacca
    36481 aactcatggg gctttaaatg gtctgatgaa gttgtagcct ttctgatgaa accttatagc
    36541 tattctatgg gtattctggc tctcttggta gctggtacaa cagctaagtc attgactgac
    36601 tcagtaaacc ggagcatgga aaaaaccaat caaatcaact atatgtcaac attgttggca
    36661 gcaattgttg gtttgttgat gttggcagct gatcctatcg aaagtggtct agctactgga
    36721 ttcttgggga caaaaggttt gctttcagcc ttccttgctg cctttgttac tgtagccatc
    36781 tataaggttt gtgttaagaa caacgtcact attcgtatgc ctgacgaagt tccaccaaat
    36841 atctcacaag tctttaaaga tgtgattcca ttcactctat ctgttgtttc tctttatgct
    36901 cttgacttat tagcacgtta ttttgttggt tctagtgtgg cagaatcaat cggtaaattc
    36961 ttcgcaccac tcttctcagc agcagacgga taccttggta ttaccattat ctttggtgcc
    37021 tttgccttct tctggtttgt tgggattcat ggtccatcta tcgttgaacc agctatcgca
    37081 gctattacct atgccaatgc cgaagttaac ttgaaccttc tccaacaagg gatgcatgca
    37141 gacaagattc ttacttctgg tacacaaatg tttatcgtta ccatgggtgg tacaggtgcg
    37201 acattggtcg ttccatttat gttcatgtgg ttgacaaaat cgaaacgtaa ccgtgcaatc
    37261 ggacgtgctt cagtagttcc taccttcttc ggtgtaaatg aaccaatctt gtttggtgca
    37321 cctcttgttt tgaatccaat cttcttcatt ccatttatct ttgctccaat tgcaaacgta
    37381 tggattttca aattctttat tgaaactctt ggaatgaact cattcactgc taatctacca
    37441 tggacaactc cagctccact aggtctagtt cttggaacta acttccaagt gctatcattc
    37501 attcttgctg cccttctaat tgtggttgac gtagttattt attacccatt ccttaaagtc
    37561 tatgatgaac aaattcttga agaagaacgt tcaggtaagt ctaatgatga attgaaagaa
    37621 aaagttgctg caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa agcgggtgtc
    37681 gatgcagcac aaaataccat cactgaagaa acaaatgtcc tcgttctctg tgctggtgga
    37741 ggtacaagtg gactccttgc aaatgctttg aataaggcag cagcagaata caatgtccct
    37801 gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa tgttaccaga gtttaatcta
    37861 gttatccttg cccctcaagt tgcttcaaac tttgaagata tgaaggcaga aacagataag
    37921 ctcggtatta aacttgctaa gacagaaggc gctcaataca tcaaattaac tcgtgatgga
    37981 aaaggtgccc tagcattcgt acaagagcaa ttcgattaag gctaggaact gtgaaacagt
    38041 ctcccatcgt tacggaaatc gctatggcga atttcctaat cgccttatta attcgtcggt
    38101 aaaaagatat cgtttttacc tcctcatgtc acaattcagt gacttggtac aagaagtgag
    38161 atggagaagc atggctcact gactcctctc ctctcacttt tactttattt aaatcaagaa
    38221 ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt attttcggtg gcgcaacagc
    38281 tgcttatcaa gcagaaggtg ctacacatac tgatggaaaa ggaccagttg cttgggataa
    38341 atatcttgag gataactact ggtacactgc cgaaccagct agtgattttt acaatcgata
    38401 tccagttgac ctcaagctag cagaagagta tggtgtcaat ggtattcgaa tttctattgc
    38461 ttggtcacgt attttcccga ctggttacgg ccaagtaaat gctaaaggtg ttgagtttta
    38521 tcataattta tttgcagagt gtcacaaacg tcatgttgag ccttttgtaa ctcttcatca
    38581 ctttgacacg ccagaagctc tccactcaaa tggagacttc ttaaaccgtg aaaatatcga
    38641 acattttgta gactacgctg ctttctgttt tgaagaattt ccagaagtaa actattggac
    38701 aacctttaat gaaattggac caatcggtga tggtcaatat ttggttggga aattccctcc
    38761 aggtatccag tacgaccttg ccaaagtctt tcaatcacac cacaatatga tggtgtctca
    38821 tgcacgcgcg gtaaaattgt acaaagagaa aggctataaa ggggaaattg gtgttgttca
    38881 cgccctgcct actaaatatc ctctagatca tgaaaatcca gcagatgttc gtgcagctga
    38941 gttggaagat attattcaca acaaatttat tttggatgca acctatctgg gtcactactc
    39001 tgaaaagact ctggcagggg tagaggctat cttggctgcc aatggtggta gcttggatct
    39061 tcgtgaagaa gattttacag cattagaagc tgcaaaagac ttgaatgatt tcctaggaat
    39121 caactactat atgagtgact ggatggaagc ctttgatgga gaaactgaaa ttatccataa
    39181 tggtaaaggt gaaaaaggaa gctctaaata ccaaatcaaa ggtattggtc gtcgtgtagc
    39241 tcctgactat gtaccacgca cggattggga ttggattatc taccctcaag gtttgtatga
    39301 ccaaatcatg cgcgtgaaga aagattatcc taactataag aaaatctaca tcactgaaaa
    39361 tggtcttgga tataaagatg agttcgttga taacactgtt tacgatgatg gacgtattga
    39421 ttacgtgaag caacacttgg aggttttatc tgatgcgatt gcagatggag ctaatgtaaa
    39481 aggttacttc atttggtcat taatggatgt cttctcatgg tcaaacggtt atgagaaacg
    39541 ttatggtctc ttctacgtag attttgaaac tcaagaacgt tatcctaaga aatcagctca
    39601 ctggtacaag aaagtagcgg aaactcagat tatagactag tagaattagt cattagatat
    39661 agaattttag tgagtcaaaa agatgttcaa agattttatc caatctattt atgaaaaagt
    39721 ttatattata aatttcgaaa aatgctctca aataccgtgt ttgacgagtg aagaattgaa
    39781 aagtcttgga aaatggtatg tctcgactgg taaagaatgg atttgtcatt cagatgatga
    39841 tctggaagaa tttaaaaatc tatttttaaa ttttatcaat cctgaagaat agaaaaacgc
    39901 atagtatcag gtgttgaaac acctgatact atgcgtttta ttgtgggaag atttactttt
    39961 tttcttctga aattgagttg ttacccaggc tctttcagtt tattaaggct tgatgacttt
    40021 aatgtgttta gatagcttaa aaaggattga atcacttagt ttagaatctg aaacaatagt
    40081 atcaagattt gatatattat aaaaagtata aaaatcaaac ttattgaact tactatgatc
    40141 tgcgagtaaa tattttttat tagaattatt taaagcgatg cgttgagcct ctccctcttc
    40201 ctcgctaaaa gtagctagag ctccgttttg aataccatta cagctaacga aagctttaga
    40261 aaattggaga ttagagagat tttgtagggt caatgtgcca acaaaagcac ctgtaatatc
    40321 gcgataattt ccacctatca aaatcaaatc tgttaatttt cgttcgctta aaatcagaaa
    40381 aacaggtaga ctgttggtta cgacgcggat attgtcaata ggcaactcac gcgcaaaaaa
    40441 ctctaatgtt gttcctggtc caatgaaaat agtttctctt tcttctacta gactgcctgc
    40501 aaaatgggct atttcttgtt tttctgccgt ttggagggct tgtttttcaa tatttgatcg
    40561 ctcattagtc aaaagggagt tggttcgaag tttttcagct ccaccatgca cacgaatcag
    40621 caaatcttta tcagctaatt cctgtaaata gcgccttgca gtcatatctg aaacggctat
    40681 ttcgtccata atctgtttaa ctgttatggt tcctttacta tttactatct ctaaaatttt
    40741 ggttaatttt tcttgtttga gcatattatc acctcgtttc ctactactat cttaccataa
    40801 acaaactcat cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa atatcgaagt
    40861 ttgttttcaa aactttcgat atttttgttg ggttataact ttgatgtttc tagtttactt
    40921 tttgatgatt gagagtgatg gagaattagt ctaaaccgta gttatagtca tcgtcttgca
    40981 tggcttcaac ttcgccaaga aggtaaccat ttccgacttg agagaagaag tcatggttgg
    41041 aagttcctgt tgaaataccg ttcataacga ttgggttgac atcttcagct gaatctggga
    41101 aaagtggatc ttgtcccatg ttcatgagag ctttattggc attgtagcga aggaaggttt
    41161 taacctcttc agtccaacca acaccgtcat aaagactctc tgtgtagcct tcttcatttt
    41221 cataaagagt atagagtagg tcgtacatcc attctttgag tttttcttgc tcttcttcag
    41281 gcaattcatt gaaaccaagt tggaatttgt aaccaatgta ggttccgtga acagactcgt
    41341 cacgaataat caatttaatg atttctgcaa cgttggctag tttgttgtta ccgagatagt
    41401 agaggggagt gaagaaacca gagtagaaga ggaaggtttc gaggaagacg ctggcaactt
    41461 tcttttcaag tgggctgccg tttaggtaga tttcgttgac aatctcagcc ttcttttgta
    41521 ggtaaggatt ggtattggtc cattcgaaaa tttcttcaat ctcagcctta gtattcaagg
    41581 tagaaaagat tgatgagtaa gatttagcgt ggacagattc cataaattgg atgttattga
    41641 aaacagcttc ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc ccagtttcag
    41701 attgcatagt gtcaagaagg gttaaaccac caaaaacttt tccgaccaag tctttctctt
    41761 tgttagatag ctttctccag tcatccaagt cgtttgataa gggaatacgt gtatcgagcc
    41821 aaaattgctc cgtcagtttt tcccaagttg atttgtcgat gacatcttcg atggcattcc
    41881 agttaatggc tttgtagtaa gtttccattt aaaatctctt tctgtgttta gtattgcgaa
    41941 ctcacaatta tttctacttt accataattc tataggagta tcgcacaaaa agtcggaagc
    42001 ccgactttta aaatgttaca taaattatgt tatgacatag tagatttgat tttatcagtg
    42061 ctgcttaggg aaaaatagtg tttctatgat agaaactaaa tcacacagct ttcacattgg
    42121 ttggcgccga cttctccacc gtcatctgta aaggtacgga cgtagtagat agacttgatt
    42181 cccttgttaa aggcatagtt acgaaggatg gacaagtcac gtgtcgtttg tttattttcc
    42241 ctcttccatt cgtaaaggcc ttttggaatg tcactacgca tgaagagggt gagtgaaagt
    42301 ccttgatcca cgtgttcagt cgcagcagcg taaacatcga tgactttacg catatccata
    42361 tcgtaggcag aagtgtagta aggaatggtt tctgtagaca agccagcagc agggtagtag
    42421 attttaccaa ttttcttctc ttggcgttct tcgatacgtt gcgtaattgg gtggatagaa
    42481 gcagaaacgt cgttgatata gctgatagaa ccatttggcg ctacagcaag gcgattttgg
    42541 tggtaaagac catcttcttg aaccttgtcg cgaagttcag cccaatcagc aacaccaggg
    42601 ataaagacat ttttgaagag ttctttaaca cggtctgatg ttggaacaaa ttcaccagtt
    42661 acatacttgt caaagtaact tccgttagca tagtctgatt tttcaaagtt gtggaaggta
    42721 ataccacgtt cacgcgcaat attgtttgac tctaccaagg tccagtagtt cataagcata
    42781 aagtagatgc ttgtaaattc aacagactca ggtgaaccat attcaatgag ttgttgggca
    42841 aggtagctgt gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct atttccatgg
    42901 tcaatcgttg gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag ggcacgaacc
    42961 atagcacgga tagaacgacc aaaatcaggt gaagtcatca tgttaaccac gttggttgaa
    43021 cccaggttac atgaaacatc tgttcccatt tgaaggaatt cttgagcatc gttgatcaag
    43081 cttggttctt gaacttgaag aatctcagaa cacaagttac tcatgataat ctttccatca
    43141 acaggatttg cacggttagc cgtatcgatg ttgactacat aaggatagcc agactcttgt
    43201 tgcaatttag agatttcagt ttccaaatcc cgcgccttga tttttgtctt gcgaatattt
    43261 ggatttgcga ccaattcatc gtatttttca gtaatgtcga tgtaattgaa tggcacaccg
    43321 tattcttttt ctacagagta agggctgaag aggtacattt cttcattttt acgagccaat
    43381 tcgtagaatt tatcaggtac tacaacacca agtgatagag tcttgacacg tactttttca
    43441 tcagcgtttt ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa gacgttgagg
    43501 tagacaacac cggcaccttg acgttgcccc aattggttgg agtaagagaa gctgtcttca
    43561 aaaagcttca tgacaggaac gacacctgaa gcagctcctt catagccttt gataggtgca
    43621 ccagcttcac gaaggttgct gagggtaatt cccacaccac caccaatacg tgaaagttga
    43681 agagctgagt tgatagaacg tccgatagag ttcatatcat ccgtcacttg gattaggaaa
    43741 caagatacca actccccacg acgagcacgt ccagcattca agaaggaagg agtagcaggt
    43801 tggtagcgtt ggtggatgat ttcattggca atatcgattg caacagcttc attcccatca
    43861 gcgaaataaa gggcgttgaa gaagacacgg tcttccatat tttcaagata gtattcaccg
    43921 tcattagtct ttaaggcata ttgattgtaa aatttataag ctgccatgaa tgacttgaat
    43981 tggaagtttt ggtctttgat aaattgagcc aattcttcca agaactctgg acggtatttc
    44041 tttataaagg ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt gtctttgatt
    44101 gaatcaaaaa ccatagtgtt tggaactaca ttttctttaa agaaagcatc caaggcttcc
    44161 ttatctttat gaagcatgat ttgtccatta acaggacggt taatttcgtt attaagacgg
    44221 aagtaagtca cgtcttcaag atgttttaat cccataaaat ttcccttatc taattacaaa
    44281 agaaaggctt ctaagttagc cctaaaagca gtttcttctg gatgatgtac taagattatg
    44341 ctaattgttt cagttttcct ggttggaaac ctgaaaagac ttcagttggt gtttggataa
    44401 caggagctgc gctaaaaccg agctctttaa cttgatcgac gtactcaggt tgctcatcaa
    44461 gattgatttc acgataagag acattattac tgtccaagaa acgcttggtc attttacatt
    44521 ggacacaatt gtttttagaa taaacggtta ccattgtgta actcctcttc aaaatttaat
    44581 actatcttag tatatcagaa aataaaattt tgtcaatgat ttaaactaaa tatagtggtg
    44641 ttcttttgtt gttttcatat ataaacacaa tatatagtgt ttgtattgtg aaatagcaat
    44701 gattatccta taaattgttt ttgaagaaac tatatcctgt gttttgttat ctaggataga
    44761 agattttcag caagttatct gaaaggaaat tgaaggaaaa tccagaaaat gcttgaaaaa
    44821 aatcctagaa gatggtataa tactaaattg taagggttat cacatataac tcaaaaaaag
    44881 aaagaacaaa aggagagtca aactatggct tctaaagatt tccacgtagt ggcagaaaca
    44941 ggtattcacg cacgtccagc aacattgttg gtacaaactg ctagcaaatt tgcttcagat
    45001 atcactcttg agtacaaagg taaatcagtt aaccttaaat caattatggg tgttatgagt
    45061 cttggtgttg gtcaaggtgc tgacgtaact atctcagctg aaggtgcaga tgcagatgac
    45121 gctatcgctg caatctcaga aacaatggaa aaagaaggat tggcataagg gaaatgacag
    45181 aaatgcttaa aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca tatctactcg
    45241 ttcagccgga tttgtcattt gagactatta cagtcgaaga tacaaacgca gaagaagctc
    45301 gccttgatgc cgctctacag gcatcacaag acgagctttc tgttattcgc gagaaagcag
    45361 taggtacgct cggtgaagaa gcagctcaag tttttgatgc tcacttaatg gttcttgctg
    45421 acccagaaat gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg aatgcagaag
    45481 caggtctgaa agaagttaca gatatgttta tcactatctt tgaaggcatg gaagacaacc
    45541 catacatgca agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta ttggcaaacc
    45601 ttcttggtaa aaaattgcca aacccagctt ctatcaatga agaagtgatt gtgattgcgc
    45661 atgacttgac tccttcagat acagctcaat tggacaaaaa ctttgtaaaa gcttttgtaa
    45721 ccaacatcgg tggacgtaca agccactcag ctatcatggc acgtacactt gaaattgctg
    45781 ctgtattagg tacaaataac atcactgaaa tcgttaaaga cggtgacatc cttgctgtta
    45841 acgggatcac tggtgaggtt attatcaacc caactgatga acaagcggca gaatttaaag
    45901 aagctggtga agcctatgca aaacaaaaag ctgaatgggc gctcttgaaa gacgctaaaa
    45961 cagtgactgc tgacggtaaa cacttcgagt tggctgctaa tatcggtact ccaaaagacg
    46021 ttgaaggtgt taacaacaac ggtgcagaag ctgttggact ttaccgtaca gagttcttgt
    46081 acatggattc tcaagacttc ccaactgaag atgagcagta tgaagcatac aaggctgttc
    46141 ttgaaggaat gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt ggagataagg
    46201 aacttcctta cttcgatatg cctcacgaaa tgaacccatt ccttggattc cgtgctcttc
    46261 gtatctctat ctctgagact ggagatgcta tgttccgcac acaaatccgt gctcttcttc
    46321 gtgcgtctgt tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc ttgaaagaat
    46381 tccgtgcagc gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct gaaggtgttg
    46441 cagttgcgta taacattcaa gttggtatca tgatcgagat tcctgcagcg gctatgcttg
    46501 cagaccaatt tgctaaagaa gttgacttct tctcaattgg tacaaatgac ttgatccaat
    46561 atacaatggc agcagaccgt atgaacgaac aagtttcata cctttaccaa ccatacaacc
    46621 catcaatcct acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa ggtaaatggg
    46681 ctggtatgtg tggtgagatg gctggtgacc aacaagctgt tccacttctt gtcggaatgg
    46741 gcttggatga gttctctatg tcagcaacat ctgtacttcg tacacgcagc ttgatgaaga
    46801 aactcgacac agctaagatg gaagagtacg caaaccgtgc ccttacagaa tgctcaacaa
    46861 tggaagaagt tcttgaactt caaaaagaat acgttaattt tgattaatcg aaaagtccct
    46921 gcaactcagt tacagggatt tttttgatat tttaaaaaga attttcaaga aaatctttct
    46981 tatagaaagt ccaaccttga aaaagtagtg gtcagaacaa aaaatactta aatggttcat
    47041 aaaattcttg acaagttgga gatttaggag taaactatta accagttaag taatagaggg
    47101 gagtttctgc aatttagaaa tgaattgcaa ctagaaatat caaatagaaa gagagtttcg
    47161 atgaaaatta ataagaaata ccttgttggt tctgcggcag ctttgatttt aagtgtttgt
    47221 tcttacgagt tgggactgta tcaagctaga acggttaagg aaaataatcg tgtttcctat
    47281 atagatggaa aacaagcgac gcaaaaaacg gagaatttgg ctcctgatga ggttagcaag
    47341 cgtgaaggaa tcaatgctga gcaaatcgtc atcaagataa cagaccaagg ctatgtcact
    47401 tcacatggcg accactatca ttattacaat ggtaaggttc cttatgatgc gattttcagt
    47461 gaagaattac tcatgaaaga tccaaactat aagctaaaag atgaggatat tgttaatgag
    47521 gtcaagggtg gatatgttat caaggtagat ggaaaatact atgtttacct taaggatgca
    47581 actcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agaacatagt
    47641 cagcatcgtg aaggagggac ttcagcaaac gatggtgcgg tagcctttgc acgttcacag
    47701 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaggacacg
    47761 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
    47821 tcagctagcg agttagctgc tgcagaagcc ttcctatctg gtcggggaaa tctgtcaaat
    47881 tcaagaacct atcgccgaca aaatagcgat aacacttcaa gaacaaactg ggtaccttct
    47941 gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac taacagtcaa
    48001 gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact gcctttgagt
    48061 caacgccatg tagaatctga tggccttgtt ttcgacccag cgcaaatcac aagtcgaaca
    48121 gccagaggtg tagctgtccc tcatggtaac cattaccact ttatccctta tgaacaaatg
    48181 tctgaattgg aa
//
LOCUS       DBEJNA010000014        43621 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEJNA010000014 DBEJNA010000000
VERSION     DBEJNA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.14"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            584..958
                     /gene="dhaM"
                     /locus_tag="ACL3JB_000890"
     CDS             584..958
                     /gene="dhaM"
                     /locus_tag="ACL3JB_000890"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR0685651.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            1416..2129
                     /locus_tag="ACL3JB_000891"
     CDS             1416..2129
                     /locus_tag="ACL3JB_000891"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0685652.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2163..2765
                     /locus_tag="ACL3JB_000892"
     CDS             2163..2765
                     /locus_tag="ACL3JB_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685653.1"
                     /translation="MTIEEYNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFEIGSKMLNDLKSNYKK"
     gene            2903..3556
                     /locus_tag="ACL3JB_000893"
     CDS             2903..3556
                     /locus_tag="ACL3JB_000893"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0685654.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3566..4030
                     /locus_tag="ACL3JB_000894"
     CDS             3566..4030
                     /locus_tag="ACL3JB_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0685655.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLGDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4043..5311
                     /locus_tag="ACL3JB_000895"
     CDS             4043..5311
                     /locus_tag="ACL3JB_000895"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0685656.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5325..5585
                     /locus_tag="ACL3JB_000896"
     CDS             5325..5585
                     /locus_tag="ACL3JB_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685657.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5596..6957
                     /gene="pdrM"
                     /locus_tag="ACL3JB_000897"
     CDS             5596..6957
                     /gene="pdrM"
                     /locus_tag="ACL3JB_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0685658.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7111..8079
                     /locus_tag="ACL3JB_000898"
     CDS             7111..8079
                     /locus_tag="ACL3JB_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0685659.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8095..9087
                     /locus_tag="ACL3JB_000899"
     CDS             8095..9087
                     /locus_tag="ACL3JB_000899"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0685660.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9305..10348
                     /locus_tag="ACL3JB_000900"
     CDS             9305..10348
                     /locus_tag="ACL3JB_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0685661.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPCINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10394..12097
                     /gene="lpdA"
                     /locus_tag="ACL3JB_000901"
     CDS             10394..12097
                     /gene="lpdA"
                     /locus_tag="ACL3JB_000901"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0685662.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENISHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12161..13150
                     /locus_tag="ACL3JB_000902"
     CDS             12161..13150
                     /locus_tag="ACL3JB_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0685663.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFVGISREEIAEAVVG"
     gene            complement(13223..14293)
                     /gene="xerS"
                     /locus_tag="ACL3JB_000903"
     CDS             complement(13223..14293)
                     /gene="xerS"
                     /locus_tag="ACL3JB_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0685664.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(14877..16427)
                     /locus_tag="ACL3JB_000904"
     CDS             complement(14877..16427)
                     /locus_tag="ACL3JB_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0685665.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16443..17222)
                     /locus_tag="ACL3JB_000905"
     CDS             complement(16443..17222)
                     /locus_tag="ACL3JB_000905"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0685666.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAIYQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17209..18060)
                     /gene="ylqF"
                     /locus_tag="ACL3JB_000906"
     CDS             complement(17209..18060)
                     /gene="ylqF"
                     /locus_tag="ACL3JB_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0685667.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            18142..18327
                     /locus_tag="ACL3JB_000907"
     CDS             18142..18327
                     /locus_tag="ACL3JB_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685668.1"
                     /translation="MMSKQFLFYDIEIYFILYHAFFILSDDSLLPYLLPYLLPYIEKS
                     HQMMTFQREQKTVPVIL"
     gene            complement(18291..18467)
                     /locus_tag="ACL3JB_000908"
     CDS             complement(18291..18467)
                     /locus_tag="ACL3JB_000908"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0685669.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18519..24533)
                     /gene="iga"
                     /locus_tag="ACL3JB_000909"
     CDS             complement(18519..24533)
                     /gene="iga"
                     /locus_tag="ACL3JB_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGR0685670.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAAMGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSKNTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDE
                     RSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSL
                     ANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNI
                     GGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFS
                     SKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKK
                     DSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMK
                     DNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQF
                     LYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLK
                     KLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYH
                     LDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKV
                     FLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDH
                     YDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVG
                     NKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLRQYVH
                     NMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEE
                     VERLRSFNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRR
                     IAYELLAAKGFKDGMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQY
                     HTWSEFKKAMYQERQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKD
                     AEHNYYHWNNYNPDIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(24742..25920)
                     /locus_tag="ACL3JB_000910"
     CDS             complement(24742..25920)
                     /locus_tag="ACL3JB_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685671.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(26135..29785)
                     /gene="addA"
                     /locus_tag="ACL3JB_000911"
     CDS             complement(26135..29785)
                     /gene="addA"
                     /locus_tag="ACL3JB_000911"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0685672.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLSRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIDSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADTYNEERKTQ
                     FAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEKNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29782..33057)
                     /gene="rexB"
                     /locus_tag="ACL3JB_000912"
     CDS             complement(29782..33057)
                     /gene="rexB"
                     /locus_tag="ACL3JB_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0685673.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKVSRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQTEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKRLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKNLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33257..33412)
                     /locus_tag="ACL3JB_000913"
                     /pseudo
     CDS             complement(33257..33412)
                     /locus_tag="ACL3JB_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            33510..33893
                     /locus_tag="ACL3JB_000914"
     CDS             33510..33893
                     /locus_tag="ACL3JB_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0685674.1"
                     /translation="MFVSYFNLLFSIDYINCLSETTDKNWHKSDRIFVTNTGKPVHSS
                     ILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTS
                     IYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(34031..35335)
                     /gene="eno"
                     /locus_tag="ACL3JB_000915"
     CDS             complement(34031..35335)
                     /gene="eno"
                     /locus_tag="ACL3JB_000915"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0685675.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            35499..35945
                     /locus_tag="ACL3JB_000916"
     CDS             35499..35945
                     /locus_tag="ACL3JB_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0685676.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(35942..37041)
                     /locus_tag="ACL3JB_000917"
                     /pseudo
     CDS             complement(35942..37041)
                     /locus_tag="ACL3JB_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(37050..37379)
                     /locus_tag="ACL3JB_000918"
     CDS             complement(37050..37379)
                     /locus_tag="ACL3JB_000918"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0685677.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVEQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(37324..37698)
                     /locus_tag="ACL3JB_000919"
     CDS             complement(37324..37698)
                     /locus_tag="ACL3JB_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HGR0685678.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVCGVW
                     WIPIVGEISKIPWYCLFHCQPA"
     gene            complement(37757..39190)
                     /gene="glgA"
                     /locus_tag="ACL3JB_000920"
     CDS             complement(37757..39190)
                     /gene="glgA"
                     /locus_tag="ACL3JB_000920"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0685679.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(39187..40326)
                     /gene="glgD"
                     /locus_tag="ACL3JB_000921"
     CDS             complement(39187..40326)
                     /gene="glgD"
                     /locus_tag="ACL3JB_000921"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0685680.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     FRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEHGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(40316..41458)
                     /locus_tag="ACL3JB_000922"
     CDS             complement(40316..41458)
                     /locus_tag="ACL3JB_000922"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0685681.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(41448..43376)
                     /gene="glgB"
                     /locus_tag="ACL3JB_000923"
     CDS             complement(41448..43376)
                     /gene="glgB"
                     /locus_tag="ACL3JB_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0685682.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFASLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT        12612 a         8759 c         8639 g        13611 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat cctagtatta gacaaaatgc tatggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttattaaag gagagtaagt aaaggtagca gcattttcta
      181 actcctaaaa acaggatagg agaacgggaa aacgaaaaat gagagcagaa tgtgagttct
      241 agttctcatt tttttcatga aaatgtgcaa aatatagtag attgaaacta gaatagtata
      301 cctctacttc taaaacattg ttagaaatcg atttgattgt cctgttctta tttcatttta
      361 ctatatctta acagatagtg taaataaaga taaactattt actggctaat taatcagtta
      421 aacactagtt aaggagtaat gatgaaaaaa agaacaatac tattattgat ggccagtctg
      481 ttagctcttg tcttaggagc atgtggtttc ttggacatat tgttcctgga tcattctcat
      541 caggattact atttactgct attttagaaa ctggggtggt ttgatggaaa gtattggtct
      601 tgttatcgtt tcacattcca aacatattgc agaaggtgtt gttgaactaa ttagtaaagt
      661 agctaaagat gttccgatta cttatgtagg aggaaccgag ggcggaggaa ttggaacgag
      721 ttttgatcaa gtagataggg ttgtttccga aaatccagca gatactttac ttgccttttt
      781 tgacctaggt tctgctaaaa tgaacttaaa aatggtgact gatttcagtg ataaaagtat
      841 catcatcaac agggttccaa ttgtagaagg tgcctataat gcagctgctc ttcttcaggc
      901 tggtgcagaa ctgtcagtta ttcaaacaca gttagcggag cttgaaatca ataaataagg
      961 aattttacta taactctttt tataggtaag ctattgatta tctcaactat aaaatgttaa
     1021 gtaaatgatt tcaaaatcag aaagggattg ctttatgcag ttccttttta ttttaacagg
     1081 agtgaaacta tagtgtttct aaattgtgaa tcaatcaaaa ctgattgtga tggggctatt
     1141 ctagctttag aatccttcaa aaattaaaat ttaaggcaat caattacttg gaagagtatg
     1201 aaagcattta gtttatagga attctaggtc tagaattaca tatgtattta tgaagacggg
     1261 gtgttcgata gttagtattg ttctattctg aaagatttga gctgtcagtt gtatagaaag
     1321 tgttcgaatt tttttaagtg attaaattag ttaattgtat gaggtgcttt atgatataat
     1381 gttcttaatg aattttcaga aaggaaaacc tcaaattgtt ctacaaattt ctactcttcg
     1441 acctcgacca cactcttctt gattttgatg ctgctgagga tgtggctttg acccaacttc
     1501 taaaagaaga aggagttgcg gatattcagg cttataaaga ttattacgtt cctatgaaca
     1561 aggctctctg gaaagacttg gagctgaaga aaatcagtaa acaagagttg gttaacacgc
     1621 gcttttctcg tttattttct cattttggac aggaaaaaga cggtagtttt cttgcccagc
     1681 gttaccaatt ttatctcgct cagcagggac aaacactatc gggcgctcat gatctcttgg
     1741 acagcctcat tgagcgtgat tatgacttgt atgctgcgac aaatggcatt actgccattc
     1801 agacaggacg tttggctcaa tctggtctag taccttattt caatcaagtc tttatctcag
     1861 aacagttgca aactcaaaag ccggatgctc tcttttatga aaagattggc cagcaaattg
     1921 ctggatttag taaagaaaag acgctgatga ttggagattc tctaaccgcc gacattcaag
     1981 gtggcaataa tgcggggatt gacactatct ggtataatcc tcatcacctc gaaaatcaca
     2041 cacaagccca gccgacttac gaagtctatt cttaccaaga cttgctggat tgtttagata
     2101 aaaatattct tgaaaagatc acattttaaa ggagacgagc taatgactac aaaaaagcta
     2161 atattactat tgaagagtac aatgaagctg ttaattatga atttacatct gacacttgtc
     2221 aattagcaaa tagtatttat caatctcttt ttaagttttt tgataagaaa aatttctctg
     2281 gcgatttaat ttttacttgg aaatctccat cattagtcaa agaaggggat tatattggga
     2341 gaagggattc acaagtagat aatcttagag taataggaaa tatatttccg aattatctta
     2401 ctaatcgaaa atatagcctc aatatgaatc gtaatggctg tatgggagat tttcctcatg
     2461 acttttttga tatataccta gatcatgtag caaaatatgc ctacgaacaa aaagttaata
     2521 atattaaaga gtattatcct ttaaaaagag cgattttaca ccaagagaat gcattgtatt
     2581 ttcgattgtt ttctaatttt gacgactttt tagaaaaaaa ttatttaaag actatatggc
     2641 aagtttctaa agaaactcct ttttctgaaa tggattttaa tatgtttaaa aatatttcag
     2701 aaaagataat cttcgaaata ggtagtaaaa tgcttaatga tttaaaaagt aattataaaa
     2761 aatagccagt ctttataaac tgtattcacg tattcaaatc gtatatatag tcgatttatt
     2821 aaatctttag ataaactgta aaaagtggtt tccatagcca ctttttgcta taatagaggc
     2881 agtaaaaatg aaggagttgg ctatggaaca ctcgtcttgg cacgctttga ttaaggcgca
     2941 attacctgag ggttatttcg ggaaaatcaa tcagtttatg gagcaggtct attctcaggg
     3001 gactatttat ccacccaagg aaaaggtttt tcaggctctc ttgacaacac tgcttgaaga
     3061 agttaaggtg gtaattctag ggcaagaccc ctaccacgga ccaggtcaag cgcagggctt
     3121 gagtttttct gtacctgact ctatcccagc tccaccatcc ttgcaaaata tcttgaaaga
     3181 attgtcagat gatatcggag ttaagaaatc tcatgatttg acagcttggg ctgagcaagg
     3241 agtcttgctt cttaatgctt gtttgactgt tcctgctgga caggccaatg gtcatgctgg
     3301 tcaaatctgg gagcctttta ctgatgctgt gattcaggtg gtcaatcatc tagatagacc
     3361 agtcgttttt gtactctggg gagcttatgc acgtaagaag aaggcattag ttaccaatcc
     3421 tcatcacttg attatcgaat cagcccatcc aagtcctttg tcggtttata gaggattttg
     3481 gggttccaag cccttttcca aggccaatgc attcttaaaa gagacaggac aagagccaat
     3541 cgattggctt agataaggag aaaatatgcc tcagttagcg acgatttgct acattgataa
     3601 tgggaaagaa ctgctcatgc tccatcgtaa taagaaaccc aatgatgtcc atgaagggaa
     3661 atggattggt gtgggtggta agctagagag aggagaaacg ccccaggaat gcgcggtgcg
     3721 tgaaatcctt gaagaaacag ggctcaaagc caagccagtt ctaaaaggtg tcatcacttt
     3781 tcctgaattt acaccagatt tagactggta cacctatgtt tttaaggtga cggagtttga
     3841 gggcgacttg attgactgca atgaggggac gctagaatgg gttccctatg atgaggtttt
     3901 gagcaagccg acttgggaag gtgaccacac ctttgttgag tggcttttag gggataaacc
     3961 cttcttttca gccaagtttg tttatgatgg ggataaattg ttggataccc aagttgattt
     4021 ctatgaataa aggagaaagc agatgctact aatcaaaaat ggtcgtgtaa tggatcctaa
     4081 gtctggtttg gatcaagttt gtgatgtctt agttcaagat gggaaaatta tcaaaattgc
     4141 gcctgagatc acggaagaag gagcagaaac gattgatgct actggtcttg tggttgctcc
     4201 tggtttggtc gatattcatg tgcatttccg tgaacctggt caaacacata aagaagacat
     4261 tcatactggt gccctggcag ccgctgcagg tggttttact actgtcgtca tgatggctaa
     4321 taccagtcca accatttcag acgtggagac tttgcaagca gttctccagt cagctgccaa
     4381 agagaagatt aatgtcaaga cagttgcgac cattactaaa aactttaatg gtaaaaactt
     4441 gactgacttt aaggcgctct tagaagctgg tgcggttggt ttctctgatg acggtattcc
     4501 gcttgagagc agtaagattg tcaaggaagc catggaggaa gccaaaaaac tcaatacctt
     4561 tatcagcctt catgaggaag atccaggttt gaacggtgtt cttggcttta atgaaaatat
     4621 tgctagagaa catttccata tctgcggtgc tactggggtg gctgagtacg ctatgatggc
     4681 gcgtgatgtc atgattgcct atgcaactaa agcccatgtt cacatccagc atttgtctaa
     4741 ggaagaaagt gttaaagtag tggagtttgc tcaggggtta ggtgcagaag tcacagcaga
     4801 agtagcgcca cagcatttct ctaagacaga agcacttctt ttaacacaag gtagcaatgc
     4861 taagatgaat ccaccgcttc gtttggaatc agaccgtcgt gccgttatcg aaggtctcaa
     4921 atcaggtgtc atcacagtta ttgcgactga ccacgcgcct catcatgtag atgaaaaaaa
     4981 tgttgaggat attaccaaag cgccatctgg tatgactggc ttagaaacat ccctgtctct
     5041 cggcttgacc tatttagtag aagctggtga gttgagcttg atggaattac ttgaaaaaat
     5101 gacatacaac ccagccaagc tttacaactt tgaagcaggt tacttggctg agaatggtcc
     5161 agcagatatc actatttttg atgccaaggc tgaccgcctt gtggactccc attttgcttc
     5221 caaagcagct aattcaccat tcatcggtga aaccttaaaa gggcaggtta aatataccat
     5281 ctgtaaggga caaatcgtct atcaagcttg ataggagtta gaatatgaat tattttcgaa
     5341 aacgtaggga gagacaagcg aaatctaata gtggaattta ctgtcccgca gctaatcgtt
     5401 ccaaaattca atatgaaact aaagaaaaag ctgaccatgc ggttcaatat gataacggag
     5461 gtttagttag aagctattat tgtcgtacat gtgcgtgttg gcatactact tcaaaatcta
     5521 ataaacctcc gctaagtttg aaaaactatg gtctgaaact ctttggttta gataaatcag
     5581 aatagaaaga gaagtatgta taagacaaag tgtttacgag agaagttagt attattttta
     5641 aaaattttct tcccaatcct gatctaccaa tttgccaatt attctgcctc ttttgttgat
     5701 actgcaatga caggtcaata caacactatg gacttggctg gtgtatctat ggcaaccagt
     5761 atctggaatc ctttctttac atttctaaca gggattgtgt cagccttggt gcctatcatt
     5821 ggtcaccatc ttggtcgagg caaaaaggaa gaagttgcgt ctgattttta ccaatttatt
     5881 tatttggcct tgggcctatc tgtggtcttg ctggggatgg tacttttctt ggcaccaaca
     5941 atcttgaatc atattgggtt agaagcagca gtagcggcag tagcggttcg ctatctttgg
     6001 tttttatcta tcgggattat ccccttgttg ctctttagcg tcattcgttc cttgctggat
     6061 tcgctgggct tgaccaaact gtccatgtac ctcatgcttt tgttactccc tctcaatagc
     6121 ggatttaact atctcttgat ttacggtgcc tttggtgttc cagaactggg aggggctggt
     6181 gctggtttag gaacatcctt ggcctactgg gtcttgcttg ggatttctgt tctggtttta
     6241 tttaaacagg agaagctcaa agccttacac cttgagaaac gaattccact taatatggat
     6301 aacattaagg aaggagttcg tttaggtctg cctattgggg gaactgtttt cgcggaagtg
     6361 gctatctttt cagtggttgg cttgattatg gctaagtttt cgtccttgat tatagctagt
     6421 caccagtcag ctatgaactt ttcaagtctt atgtacgcct ttcctatgag tatctcatcg
     6481 gctatggcta ttgtcgtttc ctatgaagtg ggagccaagc gatttgatga tgcgaaaacc
     6541 tatattggtc taggaagatg gactgccctc atttttgcgg ccttcacctt aaccttcctt
     6601 tacattttta ggggaaatgt ggccagtctt tatggtaacg acccaaaatt tatcgatttg
     6661 acagtgcgtt ttttaactta tagtcttttc ttccagttag cagatacctt tgcggcgccg
     6721 cttcagggaa ttttgcgggg gtataaggat acagttattc ctttttacct tggtttgctt
     6781 ggttattggg gcgtagcaat ccctgtggct acgctatttg attctctaac agattttgga
     6841 gcttattctt actggatcgg cttgattatt agtttgattg tgagtggggc gctctaccgt
     6901 tggcgtttaa ctgtgattat gaagagattt gaatctttag caaaatccaa acgctaaaaa
     6961 gtttgtgaaa aaatattctt gataagaaaa tcccttgttt tcacggggtt ttctttttta
     7021 ttttgtgaaa tttcttttag aaaaactttg acagtatttg ccaaaaacgg taaaatagta
     7081 aggtaagaag aaagttagaa aggcaagaag atgtcaactt tagataaaaa tcttttgcta
     7141 gaaatgttcc gtaagatgga agaaatccgt cgcatggact taaaaattgc acaattagta
     7201 aagaaaggga aagtgccagg aatgacgcac ttttctgttg gtgaagaggc agctaacgtg
     7261 ggggctatgt tagctctcaa tccagatgat ctgattacct caaaccaccg tggacacggg
     7321 caagctattg ctaaagggat tgacctcaac ggaatgatgg ctgaaatcct tggtaaatac
     7381 actggaacct gtaaagggaa aggtggatct atgcatatcg ctgaccttga tgctgggaac
     7441 cttggtgcca atggtatcgt aggtggtggt atggggatcg ctgtcggtgc agccctcagt
     7501 cagcaaatgc aaaataccgg taaaatcgtt gtttgcttct ttggagatgg tgcgaccaat
     7561 gaaggtgttt tccacgaagc agtgaacatg gcttctatct ggaacctgcc agtcattttc
     7621 tattgcatta acaacggtta cggtatctct gcggatatca agaaaatgac caatatagaa
     7681 catatccatc aacgtagcgc cgcttatgga attcctggaa tgttcatcga agacggtaac
     7741 aatgtcatcg atgtctatga aggatttcag aaagctgtag accatgttcg cagtggcaat
     7801 ggtccagtct tgattgaaag tgtaacttat cgctggctcg gtcactcatc atctgaccct
     7861 ggtaaatatc gtacgcgtga agaagtggaa ttgtggaaac aaaaagatcc aatcgaaaac
     7921 ctccgcaatt accttattga aaataacatt gcaagtgccg aagaattgga agaaatccaa
     7981 gcgcaagtaa aggaagcagt agaagcttct gttaaatttg cagaggaaag cccattccca
     8041 ccgcttgaat cagcctttga agatatttac gcagactaag gagaaagaga taaaatggaa
     8101 acaaaaacaa tgtccttccg tgacaccatt atccttgcta tgtctgagga aatgcgtcgc
     8161 gatgaaaatg tgttcttgat gggagaagac gtcggtgtct tcggaggaga cttcggtact
     8221 tctgttggaa tgcttgaaga atttggtcca gaacgcgtcc gtgactgtcc gatttctgaa
     8281 gctgccatct ctggagcagc agcaggagca gccatgacag gacttcgtcc aatcgtcgat
     8341 atgaccttca tggacttctc tgttattgcc atggacaata tcgtcaacca agctgctaaa
     8401 acacgttaca tgtttggtgg taaaggtcag gttccaatga ctgttcgttg tgcagctggt
     8461 aacggagttg gctctgccgc ccagcactca caatctctag agtcttggtt tactcacatt
     8521 ccaggactta aggttgtggc acctggaaca cctgcggaca tgaaaggcct gcttaagtct
     8581 tctatccgtg ataacaactc agttattata cttgagtaca agtcagaatt taaccaaaaa
     8641 ggggaagtgc cagttgatcc agactacaca attccacttg gggttggtga aatcaaacgc
     8701 caaggaacgg atgtaacagt tgttacttat ggaaaaatgc ttcgccgtgt ggttcaagct
     8761 gctgaagaat tagcagaaga aggaatttca gttgaaattg ttgacccacg tacccttgtt
     8821 ccgcttgata aggatatcat cataaactca gtgaagaaaa ctggtaaggt tgttctggtc
     8881 aacgatgccc acaaaacaag cggctatatc ggtgaaattt cagctattat ttcagaatca
     8941 gaagcatttg actatctaga tgcaccaatc cgccgttgtg caggagaaga tgtgccgatg
     9001 ccttatgcac aaaacctaga aaatgcaatg attccaacag ttgaaagtat caaagatgca
     9061 atccgaaaaa cttataacaa agaatagagt tgcataagat aagttatgta aataaaataa
     9121 agctgacgag aaactttgta tcttttaggt gcagagctct tcgtcattaa tatcttagat
     9181 tagagcacgg gctaaaagct cggaaaaaag ataaatctcc ttggcttcat cgaagccatc
     9241 gtcgatttcc tatttttcag tcgcttttga cgccctttgt atcataaata gaattggaga
     9301 ggtcatggct gatgacaagc taagagcgac tcctgcagct agaaagttag cagatgattt
     9361 agggataaac ctctacgacg tttctggctc aggtgcaaac ggtcgtgtcc acaaagaaga
     9421 cgtggaaact tataaagaca caaacgtggt tcgcatttcg ccacttgcaa aacgaattgc
     9481 cctcgaacat aacattgctt ggcaggaaat ccaaggaacc ggtcatcgtg gtaaaatcat
     9541 gaagaaggat gttttggccc tgcttcctga aaatatcgaa aacgatagca tcaaatctcc
     9601 tgctcagatt gaaaaagtgg aagaagtccc tgataacgta acaccatatg gtgaaatcga
     9661 gcgtattcca atgacaccaa tgcgtaaggt tattgcccaa cgcatggttg aatcttactt
     9721 gactgcgcca accttcaccc tcaactatga agttgatatg actgaaatgt tggctcttcg
     9781 taagagggtt cttgagccaa tcatggaagc aactgggaag aagactactg taacagacct
     9841 tctttcactt gcagttgtta agactcttat gaaacatcca tgcatcaacg cttcattgac
     9901 agaagatggc aagactatta tcactcacaa ctatgtcaat cttgccatgg cagttgggat
     9961 ggataatgga ttgatgacac ctgttgttta caatgctgag aagatgagtc tttcagaact
    10021 ggttgtagcc tttaaggatg ttattggccg taccttggat ggtaaattgg ctccaagtga
    10081 gttacaaaat tcaacattca caatcagtaa tttgggaatg tttggtgttc agtcctttgg
    10141 tccgattatt aaccaaccca actcagctat ccttggtgtc agttcgacaa tcgagaagcc
    10201 agttgtcgtc aatggtgaaa ttgtgattcg cccaatcatg agtttaggat taaccattga
    10261 ccaccgtgtc gtagatggta tggctggtgc taagtttatg aaggacttga aagagttgat
    10321 tgaaacgcca atctcaatgt taatttaaga gcaagagtat tcatttttaa gatatagata
    10381 aaggaaggaa gacatggcct tagaagtaat tatgccaaaa gccggcgtgg atatgacaga
    10441 aggacaaatc gtccaatgga ataaaaaagt cggagaattt gtaaaagaag gagaaatcct
    10501 tttggaaatc atgactgata aagtcagcat ggaattggaa gccgaagaag atgggtactt
    10561 gattgccatt ctcaaaggag atggtgaaac tgtccctgta acggaagtta tcggttacct
    10621 tggtgaagaa agggaaaaca tcccaacagc tggagcagca tcgccagaag ctagccctgt
    10681 acctgtagca agtacctcaa acgatgatgg taagagcgat gatgcttttg atatcgttgt
    10741 gattggtgga ggtcctgctg gttatgttgc agccattaaa gctgcccaac tcggcggtaa
    10801 ggttgccctt gttgagaaat ctgaacttgg tggaacctgc ttaaaccgtg gatgtattcc
    10861 aaccaagacc taccttcata acgctgaaat tattgaaaat atcagtcatg ctgcaaatcg
    10921 tggtatcgtg attgaaaatc ctaacttcac tgttgatatg gaaaaacttt tagaaactaa
    10981 atctaaagtt gttaatactc ttgttggtgg tgttgcagga cttcttcgta gctacggagt
    11041 tactgttcat aaaggaattg gtacaatcac taaagacaag aacgtcttgg taaatggttc
    11101 tgaattgctt gaaaccaaga aaatcattct tgctggtggt tcaaaagtca gcaagatcaa
    11161 cgtccctggt atggaatctc cacttgtcat gactagtgat gacattcttg aaatgaacga
    11221 agtgccagaa agccttgtta tcatcggtgg tggagttgtc ggtatcgaac tcggtcaggc
    11281 cttcatgaca tttggttcaa aagtgactgt tatcgaaatg atggaccgta tagttccagc
    11341 tatggatgcg gaagtttcta agaaccttcg cttgatcctt gagcgtaaag gaatgaccat
    11401 cttgactggt actaaactgc aagaaatcat tgaggaaaat ggtcaacttc gtatcaaggt
    11461 tgaaggaaaa gacgatatca tcgcaagcaa agctcttctt tcaattggtc gtatgccaga
    11521 ccttgaaggt attggagagg ttgagtttga attggatcgt ggttgtatca aggtcaacga
    11581 atacatggaa acttcagttc caggcattta tgcaccaggt gacatcaacg gtactaagat
    11641 gttggctcac gcagctttcc gcatgggtga agtttccgct gaaaatgccc ttaaaggaaa
    11701 tcatgcagtt gccaaattga atttgactcc tgcagccatc tacactctcc ctgaagtagc
    11761 agcagtaggt ttgacagaag aacaagcccg tgagaaatac gatgttgcca tcggtaagtt
    11821 taactttgct gctaacggtc gtgctattgc atctgacgca gctcaaggtt tcgtaaaagt
    11881 tatcgctgat aagaaatatg gagaaatcct tggtgtacac attattggtc ctgcagccgc
    11941 agaattaata aacgaagcat caagcatcat cgaaatggaa atcactgttg aggaaatgct
    12001 gaagaccatc cacgggcacc caacttactc tgaagtgatg tacgaagcgt ttgcagatgt
    12061 tctaggaatg gccatccatt cacctaagaa aaaataaaac gaagatagat tagactggaa
    12121 ggttatttcc agtctctatc atataaagta aagggatatc atgaaataca ttatcaatca
    12181 ttcaaatgac actgctttta atattgcctt ggaagaatac gcctttaaac accttttgga
    12241 tgaggatcaa atcttcctac tttggattaa caagccatct atcattgttg gtcgtcacca
    12301 gaacactatc gaagaaatca accgtgatta tgttcgcgaa aatggtattg aggtagttcg
    12361 ccgtattagt ggtggtggag ctgtttacca cgatttaaat aacctcaact acacgatcat
    12421 ctccaaagaa gatgaaaata aggcatttga cttcaagagc ttctcaactc cggttatcaa
    12481 taccctggct caactcgggg ttaaagctga gttcacaggt cgtaatgacc ttgagattga
    12541 tggtaagaag ttctgtggca atgcccaagc ctatatcaac ggccgtatca tgcaccacgg
    12601 ttgcttgctc tttgacgttg atttgtcagt cctcgcaaat gcccttaagg tttcaaaaga
    12661 taaatttgaa tcaaaaggtg tgaaatccgt ccgtgcccgt gtaactaata ttatcaatga
    12721 attaccaaaa aaaatcacag tcgaaaaatt ccgtgattta ctcttggaat acatgaaaaa
    12781 agagtaccca gagatgactg aatacgtctt ttcagaagaa gaattggccg aaatcaatca
    12841 catcaaggat actaagtttg gaacttggga ctggaactat ggtaaatcac ctgaatttaa
    12901 cgtccgtcgt ggaaccaaat tcactagtgg taaggttgaa gtctttgcta acgttactga
    12961 atcaaaaatc caagacatca agatttatgg tgacttcttt ggtattgaag acgttgctgc
    13021 agtagaagat gtccttcgtg gggtgaaata cgaacgcgaa gatgttctta aggcgctaaa
    13081 aaccattgat atcacacgct acttcgttgg tattagccgt gaagaaattg ctgaagcggt
    13141 agttggataa atcaaaaaga agttggccaa ctaaccaact tctttttttg atatttattt
    13201 acataattta aaatacgtaa aatcataaac tatccagagc attcttttgt tcatcactaa
    13261 caatatgggt atagaggtca gtgacttgtg tgctagcatg tcctagttgg tgactgacta
    13321 aaacttgtga tttagtcgca tcatagagcc tagttgctag tgtatggcgc agtttatggg
    13381 gtgttacacg cactttaaaa tcctctgagt atttagcaac cattttctca acgctagaag
    13441 catcgatacg attaggaaca cctctgtaga gagttaaaaa aagggctgta tctgtttttt
    13501 ccgttttata gcgttgattc cgaatggcca gataattctc taaataaggt ttagcaaaag
    13561 cagcgacatt gactgagtca cgtttgccac cttttcgagt aacatcaata accatcattt
    13621 ttagattgag atctcttaga tctagattaa cagcttcaga taagcgaaca ccagatgcca
    13681 agagaagggc aataatggct aaatctcgtt ctttattttt gttgaatgat gagagagctc
    13741 gatttgaaag ctgttgtggg tgctcttgat cgatataagt tagaaaacct gctgtttcat
    13801 cacctagaaa gagtttttgc ttgatatttt cagctctggc agcaagggtt tctttctttt
    13861 tcttggttga aacttttttc attacattac gatagaaata aggttccccc tgatcgtttt
    13921 caacctcctc ggttagatac ttgtaaagac tagaaagtgc tgataaggtt cgattgatag
    13981 ttgtctgtga aacaccttgt tttgttgtat tagcattcag caagggacgt tcacgtagat
    14041 aaaggataaa ggattccatg tctttcttag acatattttc caaaactgat aaaggaatat
    14101 cggatatttt atcagcgttt gaaataccag actccaaaac ccagctgaaa aatcggtcat
    14161 attccttaag atattcgtac agggttgtaa aactgtaggg cacagccagc ttagattggt
    14221 agtattccag aacataccag ggcatgagtt gttttagttt gtcgattcgt tccagtaaaa
    14281 tctcacgttt catgtatttt ctccataatt aagtatacta gtagtatagc atagacttgt
    14341 atgtttttca agaaaattat agtttttcag aaagatgtta taggagtttt tcaaagtgat
    14401 aaaaagactt agacctacaa acaaaacaga ataaggaaaa taataaaaat ctcacccact
    14461 aaacttctgt taatactaca taactgaaga gctatataag gagctatgag atacaaaaca
    14521 cattgtataa tagattgaaa ctagaatagt acatctggac ttctaaaaca ttgctagaaa
    14581 ttgatttgat tgtcctgatt gttttatcct atttctattt catttctcta tataattgct
    14641 attgttttct ttttcatgat tttaatctta ctgtacagat ttgatacagt aaactccttt
    14701 ctagctttat actttatcat ttctaactta attatagtct tatttttaat aaagttcaat
    14761 tatttatatg taaaattcct catcagtaaa aaataaccga tctcatttct gagaatcggt
    14821 tttctaaata aatcaaactg atcatttaca taacataaat tatgtaaatg atcatactac
    14881 aacaacaaat ctttgacttt tccaatttca ctttttggaa taaccaggtg aatcatatca
    14941 cccagataca ttctggttga gccgttaact gtttggctct tgccattatg gacttgagtt
    15001 gtgatgagga cgttgtgtgg taagttgagt tcatgaactt gtttcccagc aattttatca
    15061 gaaactggta tttcgataag tgtaacttct ccttcgctag atacttcttc tggaagcatt
    15121 ttttccagca tggcttcata gactggcgta cctttgagca aatccatgat aatataagaa
    15181 acaagagtga caagaccaag tggcataagg ttgcgaatat ctcctaccat ctcagttacg
    15241 aggatcatag cggttaaggg agcttttgat atggctccaa aatagccact cattcctaga
    15301 atgacaaata tagggaattg ctcttgactg acaagtccaa gattgacaca gataacacca
    15361 actaaggcac caagcaaaga accaagagct aaaatgggga ggaaaattcc tcctggcagt
    15421 ccacttccat agctaatcat actccaaata aagcggatta aaaagtaagc taataaaact
    15481 tggaaactaa aattttgttc agttaaagaa aggacaagct gatttccgcc accaatgatt
    15541 tgaggtaaga agattccgac tggtatgata aggataaaag ccaagatggg ataataagcc
    15601 ctatccaaat ggattttttg accaatcaag tcataaactc ttccaacgtt taatacagct
    15661 ttctcataga gaaaacctga aaatccaagg aaaattccca tgacgagata tatccaatac
    15721 tggtctaggg tcatgggagg aatgttatct ggcatatcca atactggtgt caaaccgaac
    15781 atgagtagag acacaaagtt tgctacgatg ctggctgcta gagttgagac ccagaaaaag
    15841 cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa gtgctgcaat aggagcatta
    15901 aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca aggaacgttc ctctactgga
    15961 ctggatttga gccacttggc aattccttta ccaccaactg ctccaagttg aatgctgggt
    16021 ccctctcgac ccagcatgag tccactggca atagcaagaa tacctagcac atattttttc
    16081 caaagaatgc cccaccagtt gagggacatg aggcctttca gttcggcttc gacttgagga
    16141 attcctgagc ctttaatatc tttttctgac cgtgttagtt tggcactgag ccaacagatg
    16201 agtatataaa acaaaaccag tacaaaaaga ttgcgcacta agtacccttg atcttgataa
    16261 actccttgta tcaggtggaa gcccttttca attaagaaac gaaaggatcc gacgataatt
    16321 ccaacgatga ggccgacaat gattcctcga ccaacttggg atagtatagt gctggatgca
    16381 aaggcgaatt ctttcttaga acggactatt tccgactgtt cctccatggt atttcctttc
    16441 aattaacttt cttttttacc taaaaccagt gatttaacgg gttcaaagct ggttcggtga
    16501 attggggtaa ctcctagttt tgtgaggcct tccagatgtt tagctgtgcc atatcctgca
    16561 ttagtagcga aatcatagcc agagaactgc tgatcgtatt ctttcatcaa ttcatcacgt
    16621 gttaccttgg ctactataga tgctgctgcg atagagaggg agttggcatc tcctttgata
    16681 atggaggttt gtgaaatggg caagtccagt ttcatggcat caatcaaaag gtgctctggt
    16741 tgagggctga gctggtagat tgcttcttgc atggctagtt tggttgcttc atagatgttg
    16801 acttggtcga tgacctgatt atctatgata ccaattccaa tcgacaaggc ttggtcttga
    16861 acggcttgga aaatctccag atgtttcttt ttaggaattt tcttgctgtc gttgagacct
    16921 ttaatcttac aatttttagg taaaataacg gccgcagcga ctacaggacc agcaagagga
    16981 ccacgaccaa cctcatcaat acctgcaatt aaggtcaatc cttgcttata aagttctttt
    17041 tcataagaaa gcatggattc caagcgcaaa ttttcatcta attcagcttg aatggctctt
    17101 ttacgcttgc tgatttcctt ttgaactcct gagcgattat ccttttcaag ctctaaaaaa
    17161 atagggcttt ctaactcctt gactgtcaca aggagttctt tgatttcttt aatcgttgcc
    17221 atcgaggtct tccaatgtat ctaaggtata gttaccgagt ttgccatcac ggacttcctt
    17281 cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa ccgagggcgc gggtcatatc
    17341 cataataatc acaggcgctt cttcttcaat tttcatttgt ttgaagcgtt cagccagctt
    17401 ttctggataa tgttctttga aataattgat accaaaaatg gtaacctcat ccataggaag
    17461 caactgatcc ttgatagctc cagtcaatgc caacttaagt gcaacagttt catcctcaaa
    17521 cttaggccag agaatccccg gtgtatccaa gatttccaga tctttattgg ttttaagcca
    17581 ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca gcaatctttt taccagccaa
    17641 acggttcatc agagttgatt taccagcgtt tggaatccca ataatcatgg tacgcaaggt
    17701 ttcaatctga atcccacgtt ctttctggcg agcaatctta tcagccatga gcttcttggc
    17761 cgcatctgtt acaactttta cagtcacttg ctctttggag ttgatagcta gcgtctggat
    17821 tccttgtgat tcaaaatact gacgccattc cttggtcatt gctggatcag ccaagtcggc
    17881 cttgtttaaa atcaagagtt ttggtttatc accaacaatc ttggtcaaca taggattttg
    17941 actagataga ggcaagcgtg catctactaa aatcgtcaca aaatcaacaa attttaaatt
    18001 ctcctgcacc tgtcgacgag ctttagacat gtgaccagga aaccattgaa tagtagccat
    18061 tgagtttttt cctttcatag caaggattta gatcccctat tttattttac tattgtttga
    18121 acatagagag ttttcaaatg aatgatgtcc aaacagttct tgttttatga catagaaatc
    18181 tactttatat tatatcatgc cttctttatt ttgtccgatg atagcctttt accctatctt
    18241 ttaccctatc ttttacccta tatagaaaaa agccatcaaa tgatgacttt tcagagggag
    18301 caaaaaactg ttcccgtcat attatgaacc aaaagaacta aactaccaac agctaatagg
    18361 cctaaagctg taagctcaga agttgatgaa cctgttgcag gaagagtttc ctgctgataa
    18421 ataagatcat aacttacttc attatcagta ggaattcctg cttgaatctt ggtttgttct
    18481 tcatcacctt tttaaacttt atttcctaat agtagacact attttttatt ctcaaaaatt
    18541 gaacttctaa aatcatttgt ttggtcaaga taggctttaa agattgctct cttgagcttg
    18601 tggacttcac tatctatgtc tggattgtag ttattccaat ggtagtaatt gtgttctgca
    18661 tccttacgaa cagcaacgtc cattaatttc tgtaattcat ctacactgct tgtagttttc
    18721 ttggcaaatg tttgccaagg ctgtgttgta tcattaaaag taactttgtt caatctatca
    18781 aactgatctt gtcgttcttg atacatagct ttcttaaact cactccaagt atgatattgg
    18841 ttattaaata ccttttccaa aaccaagtca tctgtaacca aacctcttgt tttaccgtag
    18901 agattgattg tcttgccctt ttgtttggct tcttcttcgt attggtttga gatatatggt
    18961 accataccat ctttaaagcc tttagcagct agtagttcat aggctatacg acgtcccatc
    19021 aggtcacctg gtgttcctat atcattactt aatgcagcat aaatcggtgc aaataactta
    19081 atagtgaagt agccatttct ttcgtattta cctgaggcat attccctaga cgaaagaata
    19141 ttattatcaa tcaaatcatt gaatgaacgt agtctttcaa cttcttctac tgttagattt
    19201 ctgacaacat ttgttgcata gaccttattt ccatcaggat caggatggta ctcatttgta
    19261 acttttctaa gaagttgttg tttttgattc gtatccaatt taagaattga atttccttcg
    19321 agatattcca acatataaac aacgtcaaac atgttgtgga catattgcct caaatcatct
    19381 gcattattaa atcttgtagt tggatcaagt acttgtaatc gtcgactttc tgtactatca
    19441 gattttgaat gtttcaagat ggagttgatg gtaatggtcg catcatctgg atggtctggt
    19501 gcttgtaata atcctttagc aaagaactct ggtcccaagc cacttcttcg accatatcct
    19561 ccaagataaa tgtcctgatc tgagtcatgt gtcatctcat gcgtataagt aatagctcca
    19621 tccttatcca acattcgata acccatataa taaactgcat cacctgtagc ataagcaccg
    19681 tgttgattat gcccaacttt atttccaaca ggtccaaaga aatgttgcat tgcaggattt
    19741 ggattatcaa aatctgccac ttctgtagct ttccctacgg tattatcatc gccaaattta
    19801 taagcatcgt aaagcaaaat atttctataa agtttttcac gtgcattgtc gtctaaaata
    19861 cgataccaat aatcgtagtg atctcgctga cgtttggctg tttcacgcgc attttcttca
    19921 acaaaatcat tgagagcctt gcccgcttta tggtcactac tgcggtagcg atcataagct
    19981 ccaaatccta gactagacat ggtcgagatg acaaatacgg atctctctgg caaggtcagg
    20041 agaggcaaga ccatattgcg gtatttccat gtggcactcg tgatacgatc ataaacaccg
    20101 atagaatact tggtgccagc taacccttgc ttcgttttca cctcttcgat agtggatttt
    20161 tcttcgacaa tgtaagcctt agtctctgat ttaaaccagt cattattgct tgtatttggt
    20221 aaaaagactt ttcggtaatg ttccagcgtg ctaaacaaat ctgtcgttcc atgttgactg
    20281 gcaagactga taccataagt atcgacatta ttcttagcta gaagattgtt aaagccagat
    20341 ttacccaact caatcagagt atctaatggt gaagcattcc ccttaccaaa gaagtccaaa
    20401 tggtacagaa ctaggtcttt gacattcacc tgaccatagc taaagttata ccaccgttcc
    20461 agataggtca agccaagtag caaggcttcc ttgttgcgtt tgattttatc tacaagataa
    20521 ccttcagtga cggggttagc actagccagt ccagcatccg ctgacaagag ttttttcaaa
    20581 ctgtcttcca gttgttgttt tgttttggcg aactggtctt ctagatagag ctcagtttgc
    20641 ttgacgtttg gagaaatacc cagcgtcttt ctgatggctt ctgaatgata gtcaaccttt
    20701 tgtaagtcag gtaagacttg cttgatgata gaggtttggt catacaggaa ttggtttggc
    20761 gtatagagaa gtccagtatt gcccagacta tattctgcta atttggcgaa atcattctgg
    20821 tatttgagat ccagcttctc agataaatca tccttgtagt gaagcaagag tttgtttgca
    20881 gtctgtttgt tagaaacaat gtctgtgatg acttggttgt ccttcatcat gactgctgac
    20941 aagagttctt tttgatataa aagactgttc tcattgacca ggtttccgta tttgacgatg
    21001 gttgccttgt tgtagaaagg tagcaatttt tcaatgtttt tataagtcaa gttgcgctta
    21061 gcttgataat aggccacctt agaaaaatca ctgtcttttt tgccacttgt tgaaagtggc
    21121 tccactgttg gtagaatgag aggattgatt tctgcttttt tgcttgcaat ttgagaagca
    21181 tctagcattg ttcctctttc ttcaaaggat tccttgctga cgacctcatc cttgaccaag
    21241 gtgacattgt agactctgtt ggccttgctg ctgaatgtgt cctttacctt catttcgtta
    21301 tagtggtaac cagtgatggc atttccgttg gttacattaa catcgctgag aacattggtc
    21361 aaacttccag catgcctaac atcaccagaa gttcgatccc acaaattgcc tgccactcca
    21421 gcgactctac caaagtgctt gacattgttg atatcacctt cagcatagct atcttggatc
    21481 tgtgcatctc ggtctactag gcctgcaagt ccacccacag tctgatctga agtatttgtg
    21541 ttagatgaaa tggctactgt cgcttttgac ttagtaagta aagccttgtc acctgtcaaa
    21601 tgaccgacca taccaccgat attgtaggca gcagtcgttt cataagtgtt gataattctt
    21661 cccttgaaac tgctctctgt gatgcttgat tgctcagcct tagccagcaa accaccgata
    21721 ccacgttcac cagccagaac accatcgacg tgaacttgct taatttttgt gttattctga
    21781 gcttcatttg ccagtgaacc gatatcatct ttccctgaaa tagcaacatt ttttagactc
    21841 agtttttcta ctgtagcacc actcaagttt tcaaacagag gttttttcaa attatagata
    21901 gcataattct tgccatcttt ttcaccgatt aaacgaccag taaaggtgtc cttgatatag
    21961 gatctttcat caggaccaag ctccacttcg ttagcattca ggctggccgc taaatgatag
    22021 gttccagagg gattttggtt tatagctttg accagattac taaaggaagt aaagtttgtt
    22081 gtttcttctg ttcccttctt agctagatag aaggtaaaat tatctttata tctgctttct
    22141 atctcctgct gaagcttctc tacttttgct gtgattttat aaaggatttt atcatttttt
    22201 ctttcctctg atattgatgc tactggtagg tatacatctt tgaatgaaga agatttcact
    22261 ttaacaaagt agctatttgg attgcttgga acttgctcta acgaaatgtg ttgtttataa
    22321 gtaccatttg acaaactgta taactctagg tcggaaacat ttcttaattc aagtgttttc
    22381 tctggttctt ctaccttttt atcagggtct agttcatttt cttgtttaat ttcttcgttt
    22441 ccatttgaat tggatgtgtt tgattcggtt gaaacatcct cagttgaatt tccgtttgat
    22501 ggttctggtt ctgtttgtcc attctctgat gttgtattac ctgaattttc tggttttgtt
    22561 gcagttccgt ttttttctgg ttgatttgat tcttcaactg gtggttttga atcactaggt
    22621 ttattggata cttctccagt attttcgtta gctattttcc cagagtttgt ttgtgtttct
    22681 tctgcaggtt gaactggttt ttctgtttct tgatttgagg taccttctac tgtgccttca
    22741 tttggattta ctggaacttc ttctacagtt ttttctgaat tttcattttt agagtcatta
    22801 tgttctggtt tatttgattc tccaactgag gttgtcgaat cactaggatt actggacact
    22861 tccccagtat ttttgctaga tgtatctggt gatactttct ctgaattcgt tgttgattct
    22921 tctgcaggtt gaactggatt ttctgcttct tgaattgagg ttccttctgt agtaccttca
    22981 tttggattta ctggtgtttc ttctgttggt tttactggaa cttcttcagt tttttctgga
    23041 ccttgttctt tggtcttctc aaccggagtt tcaggtttta cttgctcaat attaccctta
    23101 tattctggaa gcggtgctac ctgctctggt tcacctttat cacttaccac agtatctggc
    23161 gactctggtt gaacctcagt ctcacctttg tcggtcacaa ctgcttcggg taatgtaggt
    23221 tgaacttctg gttcgccttt gtcacttact acagcttcgg gcaactcagg ctgaattgcg
    23281 ggttcaacaa tagctccaga ctgtacgtcc ttatgttcta caccagtctc aggttgttcc
    23341 tttataactt gagttttttt agtacctttt tcgactattc ttggactagg cgcagtcgtt
    23401 gaagttgaaa caatttctcg cgaaacttct tccttgttta cagagaatat tctgacgatt
    23461 tcaactttct tacctaattt accttcttgt tttactctta cagttccttc agctaaatca
    23521 ggattttctt gaatttcttc ttgaaaatct atttttgtct ctatagtttc ctcacgatat
    23581 aagagttcag gtttgttcaa ttgacctgat aaaacttcat cctgtggatt taatgtattt
    23641 accccagtct tttcttttgg agaaatcttc tcctctttct tcgtttctag attcttatgt
    23701 tcggctaatt gttcttgaga atctgaagat tgtttctctt cttttcttgg attgattaat
    23761 tcagtagaga aaggtttttc aactacttga acttctgtcg gcttagttga agaaacaggt
    23821 gtttgttcct gaatagcttg tactgttgat ggatggtcta caaaattcgg tgtaacatta
    23881 taatccacct tttgttgttt tgtaggagtg gcaactgaac tcttttgatt acttacttca
    23941 gactcagaag tcgtttttcc ctctttgata tatccaatat aagtgtaacc tgaaatctct
    24001 ttaggaagag gtaatttttc tccagaggtc aattcatagt ccgtattgta atttagcaaa
    24061 agatgatttt ctaaagcatg gactgaaact aagacaccat ttcctatccc tgcaaccaat
    24121 actaaatgta ataccgtttt attcttaacc tttttcttgg aaacagcaaa aattaaaatt
    24181 cccatagcag ctaagctagc accagcaact agggcttgcc tctcattctt gcttccagta
    24241 tttggcaatt ccgccagttg attttgagaa tttaacttat aaacaagata ataagtttca
    24301 tcatcattct ccacgtatgt cggaatatca tagacaagct gcttcttttc ttctgatgat
    24361 agctctgaat ctgccacata tttatagtga actcccgcag tttcttgagc atccacagat
    24421 gaactagcta atacagacat aaaaaataaa cttgaaatcg ttgcagatac aagtcctact
    24481 gataattttc taaatgaaaa acgctcttgt ttttcaccaa aatacttttc cattattcct
    24541 ccttgaaata aaatttatat atgttacaaa gacctttatt atattagtgt attatctatt
    24601 atctatagaa aaggcagtat accttaatta tactcttaat ttacaaaaaa gtcttaaaat
    24661 tgagatgcgc tttcatactt tgttttatat tatttggagg tacaataaca cctaccatga
    24721 aatttacacg gtaggtgtta ctcatatcac taatcgttct aaaaatggtt tgaggcagtt
    24781 gaggagaatt ccttctatcc agcttccttg tgctgatgag cgatggtctt cctgcaggct
    24841 tttttttaga aaatctcgga cttgttctgg tgcgatttca aattcaaagg ctttcatttt
    24901 atagaaaaag tcgatgagat gatctgacag gtattcagtt gaaaagggta cttcaccact
    24961 ttttctatat tctaataaga gtctagaaaa tcgagctttt tcttcaggaa gctcacgaaa
    25021 ataggaattg aggagccaag tctgcttctg ttttctttca attggatcct gactggcaat
    25081 tcgttggtct ttttccagct ctttttggta ttgtttggcc ttgatagccc gttctgctct
    25141 atttttacca aaaagaattt tttcccactt gcgttcttct tgagtcaggg tctctgtaaa
    25201 gccaaagtaa tcttgataag cacgctctgc gggtcccatg gctagaacca gattgtctgc
    25261 atattgcttg gcgattttat ccctcttctt gcgttctttc tctgcctgga tacggagttc
    25321 ttgttcgtag tcaattttct ccttgcctag cttgacaagg tagagttggt catccgattt
    25381 cccaagtaaa aagggtttga tacacttttc aaggacttct tccatccgag cctttttctt
    25441 tggttccgcc ttggtccaac ttcctccctg aaagacttct aggaaaagct ggtagtctct
    25501 ctcaggcgca aattgattgc cacgattggg tttgaaaaca cctttttccc agagccattt
    25561 tagaagtcgc tcgtcaaagt cacttttatt gaccttaatt ttttcctttt tctgagcttt
    25621 tctggttaga ttttcaacct ttctgagcag tttttcttcc tcttccaatt gctggtcaag
    25681 ggacaatcga tgaaaatgac gaacacagtc gctaccaatt ggaaagaggc gttggcctgt
    25741 gacaccgtta aagagttcat aagcgtattt gatggcattt ccacagacac aattgctacg
    25801 gccgataccg ttaaaaatca aggaaacttc attccattcc ttggtagctt gttcccaagt
    25861 atccgctttc gaagcctgta aaactgcatc gtgcagggat tttctaactg gaagtgtcat
    25921 gaggtctcct ttctaatact caataaaaat caaagagcaa actagaaagc tagccgcaat
    25981 cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagct caaaacactg
    26041 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat atatacagca aggcgaagct
    26101 gacgtggttt gaagagattt tcgaagagta taagttatac ttttacaact tgaacctcgt
    26161 ctttaccgag taaaatcaag tatttttcaa tattttcaat cgaataggct cgtgataaag
    26221 cctcttcgta tagagctaac tgaccacgat agcggtctac gagttgactt ggttcatcat
    26281 agcggtctgt cttgtagtcg aacagaacaa ttttgttttc gtaaagcaga tagccatcaa
    26341 ggataccacg gacaacaaag tcttcctgac tcttttggtc tcgtttgagc atggagaaag
    26401 gttgctcgcg atagagatgg tcggtattag caagaatttc ctgaccgagt gctgtgtcaa
    26461 agaaagcaag aattttatca agattgatct tgtctctgac agcttggcta gtttgaactt
    26521 gtttgagtgt ttctgttagg ctagcaaggg ttagttgctg gctgaggtca attctctgca
    26581 tgagttcgtg agtagcacta ccaatctcag ctccagttac cttttctttg gttgaaaaat
    26641 ctggcaaatc gaagctgatt ttcttgccta ctgactgacc ttgaccagca atctcgacac
    26701 cttccatatc cataactggt tcgtagaatt tcttgatttg acttggggtt tgaacactag
    26761 gaagttcaat agctgcgcgg tgaagagtat tataaacttc cacctccttc agcatttcca
    26821 gagcttcttt gatggtatct gactgacgat tgtctgcttg ggagctatct tggagaggac
    26881 tcttggtttc caactctccg atagcttctc tggtcaactg atcttcgcca ataaaacgat
    26941 aactaaagtt gagcttgtcc ttagtaaaca ctttactgat agcccaaagc caatcttgga
    27001 aattccgtgc ttgcagtcta gtattgctat ttagtttccc atttttggct gctgggtatt
    27061 gcttggcttc cagcttttca cgagaaccct tgccgacaag atagagcttt ttctcagccc
    27121 gcgtcatagc aacatacagc aaacgcatct gctcagaata gcttgctagc tgtaattcct
    27181 cttcattctg cctataggtc aggctaggaa tggagagttt gatggtttta ggatagtggt
    27241 cttctactgc ccctgtctcc atcttggcaa tatatttgac accaagacca ttctgacgac
    27301 tgagaatgac ttctgacata gagtcttgct tgttgaaatc ttgatccata ttgaggataa
    27361 agacgtaagg aaactccagc cccttactct tgtggatggt catgagctct actgcatctt
    27421 ttggcggtgc gacggccacg cttgccaaat cgtgctgggc ttctaagact tggtcaatca
    27481 tacgaataaa acgcgataaa cctttgaaat tgctcttttc aaattgatca gcacgcagtg
    27541 ctagggcata gagattggcc tgcctagcag gaccattcgg caaagcccca acatagtcat
    27601 aataaaaacg gtcgttgtaa atcttccaaa tcaagtcata gagagagtgg gttttggcat
    27661 acaagcgcca agaagctagg atatccatga attgctttag tttttcagct agagctgtgt
    27721 gaatcaaacc tttttgacta cttgccattt tttgtgcatt gaccagtttc tcatagagat
    27781 tttcgtggac tttatcctct gctttctgaa gggacaaacg tgctagctca tcctcatcaa
    27841 aaccaaacat tggagacttc ataagggcaa ccaaggcgta gtcttgcagg ggattgtgaa
    27901 tgacacgaag agtgtctagc atgacttgca cttctaggga ttggagataa ttgtttttct
    27961 ctccgtcagt tttgacagga attccgtact cagacagggc gaggagaatc tggtcattac
    28021 gactgcggct ggaggtcaga agggcaattt ccttaaaggc aacacctttt tcttgatgaa
    28081 gtttcagaat ctccttgata actaagcgca tttcgcctgt tagtttcgtt tctgtttgac
    28141 tctcttcttc ctcacctgta tcgtccttat cgtagaggag aaattcggcc ttgttgtctg
    28201 gattgggagt cagtttggta ttggcaaaaa caagctggtg catgttatca tagttgattt
    28261 cgccgacctc ttggtccatg agacgttcaa agacatcatt ggttgctgac agcacttctg
    28321 aactactacg gaaattttcc ttgaggagaa tgagcttgcc ttcttgagga ttttgcgcat
    28381 agcgttggaa tttctcattg aaaatctgcg ggtctgcctg acggaaacga tagatggatt
    28441 gcttgatatc tcccaccata aagcgattgt ggccattaga caacaattcc agcatccgtt
    28501 cttgaatatg gttggtatcc tgatactcat cgaccatgac ttcatggaag cgctcctgat
    28561 aagactcacg aacttgtggg aaattctcta aaatctcaat ggtgtaatgg ctgatatcag
    28621 cgaattcaaa ggcattttcc tgtcgttttc tctgacgata agcctctaca aaatcgctca
    28681 tgaaagattg gaaggtttta gctagtttcc aagtgtctcc atgataacgt tcttgatagt
    28741 cgagaatcgc tatctggtct gataattgtc ctagtttagc aaactgggtc tttctctctt
    28801 cgttgtaggt atcagccagg ggcttcaaat cagccttacg gctggcatta gtcagagctc
    28861 gaccgttttt ctccttagag atggcgacaa cacgcgcaag cactgcctga taagcctgac
    28921 tatcggactc ctgatttagg gagtcaattt catccagaat taactgaaca ttttctaaat
    28981 aggcagcctt tgcaaactcc ttggcatcgt tatccagatg gtaacggaaa aagctttcca
    29041 aatcccaaag ggcttgtttg atttgctcag tcagtttttc tttttcactg gtaaaatcag
    29101 ctttctcaaa tcctttgagg aaagattcac tcagccactt ttgaggatta ctggtggatt
    29161 ggaggaagtc atagatttta tagacctgct ggcgcagacc ccgttcgtcc ttgccacgcc
    29221 cagcaaagtt tttcagcaaa tgactaaagg tctctttctg tttaccttgg taatgcgctt
    29281 caaagacctc atgaaagact tcgttttcga gaagaagttg ctcgctttgg ttttgtaaaa
    29341 tacggaaatt aggtgcaata tcaagcagat aaccatgttt gccaaggaat ttttgtgtga
    29401 aagagtccat ggttccgatg gcagcgttgg gtaggtctgc caactggcga ctcaagtgtt
    29461 gtttgagctc gacatcatct gtttcttgga ttttcttgct gatttttttc tctaaacgtt
    29521 ctttaagttc agttgcagcc ttgacggtaa aggttgagat aaagagttga gaaatttcga
    29581 caccacgcgc caattggtcc agaatgcgct ctgccatgac aaaggtcttt ccagaaccag
    29641 ccgatgctga gaccaggata ttctggccag aagtgtagat agcttcgatt tgctcggcag
    29701 ttttcttctg ttccttgctc gaatttgctt ctgcttcttg cagtttttga atctcctcct
    29761 cacttaaaaa gggaataagc ttcatcgatt caactcctct cttatttttt caagccaagc
    29821 ttgcttgagt ttttctccga ccagacgctt gctatcagct aggtccaact tttttaggaa
    29881 acgggcttgg cccagatggt aattggcttc aaagcctgta atagcctgat gttgctggac
    29941 gtatggggca atgcttctgc cattttcagt ataaggattg atggcgaacc ggcctgctaa
    30001 aatcttctca gcagctttct tgtaaagata ggcattgtag tccagtagga gctgaaattc
    30061 ctcatctgtc agttgattag ccttgttttt gttataaaat tcgcctaaat aactgctttc
    30121 tttttccaag aagagccctt ggtatttcat agatttgctg gcttctacca ctgctcctgc
    30181 aagatttttt accgccatca gagattggac aggttcagcc atttccaagt acatggcgcc
    30241 gaaaaagttc tgctcccctt ctctttttag ggcagcaaga taggttggta actgagaatt
    30301 gagcccatta aagaaatgag gaaactggaa ctgagtcaga ctggatttgt agtctactac
    30361 tcctatcgct ccattagctt tcaaacggtc aatccggtcc accttgcctc gtacaaagac
    30421 actgcgtcca ttgtctaatt gaataaaggc ttggtctttt ccaccaaaat ttgcttcttc
    30481 tttgatggtt tcgatggctg gattgtgtcg gagaatatgt ccagtcgtcc gtgcaacatc
    30541 aagcaaaact tccttggtaa actgggcttc caaactttct tgataaatag cttcaaattc
    30601 gcgttcttga ctggtttctt gaatagcttg ttctagacgt tggtcaaagg aatcttcatt
    30661 aggcaactgt aaggcgcgtt caaagatacg atgcaagaaa ttcccgtgac tacgggcatc
    30721 aggatgcaaa cgtaattcct cctgcaagcc taaaacgtag cgtaggaaat aactgtattc
    30781 attgcgataa aactctgtca aacccgacgt agacaggtaa aactcctgtt tggcaggata
    30841 gagagcttgc aaggtgtcct tggctaaggt cttgctgctt ggactggttg ggatagctgg
    30901 attttccaga ccttgctgat ctagtttttt acctatgaca cgcgacagaa ccttgacaaa
    30961 agtcaaatct tgctcagtat cgctcatctc accctgctgg tgataggcaa ccagactaga
    31021 caaaagactg tgataggacc ccatatcctc cttagacagt cttttgtgat tcatcctctt
    31081 ctctctccgc ctaaatccaa aatggatcaa ctcttgaaga taggcagatt ccttactttc
    31141 actttcgtta aaaaggcttg gagccgacaa gaacaactgc ttacgagcag aattgaccaa
    31201 ggaaagcata gtgtagcgat ttttcttgag attttcactg ctggcaatca gtaattgaac
    31261 gccttcttcg gtcgcttggt ttaggttttg cctttcttca tctgtcagaa gactggtgtt
    31321 ttgagaaatt tttggtaaat tgtcctgagt tagtccaata gcatagacaa agtcagcagt
    31381 caatggtgca atcaaatcgt aactctgcac cagaacagtg tccactgttg ctggaatggt
    31441 acggtattgg gacaaactca ttccagaatg gagcaaggct aggaagtctt ccagactaac
    31501 ctgtgaacca gcaaaaacag tcgcaaattg ttctaaaaca tggcagaaag ccttccaaac
    31561 ttcggtttgt ctttcctgtt ctacagcttc caaagtggtt gtcaaatctt gtaactgctt
    31621 agtcacagct ccttctttta gaaagacact ccatttttgt aggaggtttt cagccttttg
    31681 ttttcggctg gcaaagaggg tttcaagagg tgctaaaatt ctcaggcgga ggacattcaa
    31741 acgctcaaga ttaaattttc catggtggga tttggtgaag gtttgctgaa aggctggcaa
    31801 gccattgata ccaagatagc ggatatattg ctcaaaagca tcaatatcag actgactgag
    31861 gtcagtatac aaatcagttc taagaagatt aatcaaatcc tcctgacgaa aacggtaacg
    31921 ttttaaagct aaaatagact cgacaaactg agtcaaggga tgatgagcca tggcttcgct
    31981 tctaccaaga taaaaaggaa tctgatactg gtcaaaaata gttttgagag ataactggta
    32041 agaagctaca tcccccaaga gaatacgaaa atgcttgtag ctcaggtctg agttctcatg
    32101 taatttctga cgaatactac gggctactag ctccaactcc tccttttgcg tcaaacaaga
    32161 ccagatttgt aaattttcac ggtctttctc atcgacatcc aaagcgagtt ctgaaaagtc
    32221 ataagaagac tccaacaaac gagagacctt gtcaaaacta tccatcttct catgagtttg
    32281 agaacagtcc tgagcaggcg tttggtattt agaagccaga tgatggagaa attttacgct
    32341 ggcttggtag agattgccct cgctaaaagg actggtatag gctttcttac tagcataagc
    32401 cccgataaca atctcaacac ctttgccgtg aagtaagtcc acaacccgct cttcctcagc
    32461 agaaaaacga gtaaagccgt caatgaccaa ggtgatttga ttaaaatcac tacttacctt
    32521 gtcattctca atagcctcaa tcaaatggga caactgactt ccctgggcta actgaccttg
    32581 attaagatag gctgttactt tctcaaaaat caagagtaaa tccgtcctct tatcctcatc
    32641 tgttaaattc tccaagtcca aaaaactcat ctgagatttg gtcatctcat ggtaaagctc
    32701 aattaactgc tggatcaatt gaggatcctg cttaatagcg ccataaacac gcaagtcctt
    32761 gggatcgagt tcggcaaggc atttgtaaaa ggccaaccca agaccgatat catcaagagt
    32821 agttttaact ggtaaatcat tcaagaccag ataacgagcc atttgagcaa agcgcgtgac
    32881 ggtaatcgaa aaagaagcct gctgggacaa gcattccagc acggcgcgtt ccttttcaaa
    32941 agaaagagag ttgggggcaa tgtagaagac ccgcttgcca gctgcaacta gctcttctgc
    33001 ctctcttgtt agaatttctg tcaaagaagt tcgaatatca gtataaagta atttcatctc
    33061 agcctcgttg gaatttttca tcaccctata ttataccatg attagcctcg taaatctgtt
    33121 aaaatattta ggccatcctt tcttttcttc atcatctgct aaatcttaaa tacttagctt
    33181 tacttgtatt agatagaata agtctggcca ctgaaaatca tataataaaa aagcctcggt
    33241 aacaaggctt tgagttttat gattgtttct taggtacgga atacacttca atgtgttgtc
    33301 ccagtgtctt aatgtcgacg ggtagattgt ctgatttatt gccatcaaca tcggactcta
    33361 attcgatatc agaagaagtt ttaatattac gtgcctttat atattcaata ttcttgatag
    33421 aatgattgaa ctatagtaaa ttgaaactat aatagtacac cgtggatgct aaaatatttc
    33481 tagaaattaa tttgatttcc ctaatcaagc tgttcgtatc ttatttcaat ctactatttt
    33541 caattgacta tataaattgt ctaagcgaaa caaccgataa gaattggcac aaaagcgacc
    33601 gtatttttgt taccaataca ggaaaaccag ttcatagttc tatcttgagc aagtctctcc
    33661 agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca tctgtcccct cacatcttca
    33721 gacacaccac tattagcatc ttatcagaaa ataaaattcc tttaaaaaca atcacggaca
    33781 gggttggtca ttccgactct gaagtcacta cttccatcta cacccacgtc acaaagaaca
    33841 tgaaagatga agcaatcaat gtactggata aagttatgaa aaagattttt taaaaagttt
    33901 tgcccctttt ttgtcctcta aatacaaaaa tagcccttcg gataaaatcc gaggggctag
    33961 aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg gttcgggata aaatagttca
    34021 ctgaactatt ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
    34081 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
    34141 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcgatatca gcgattgttg
    34201 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
    34261 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
    34321 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
    34381 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
    34441 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
    34501 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
    34561 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccaa
    34621 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    34681 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    34741 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    34801 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    34861 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    34921 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    34981 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    35041 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    35101 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    35161 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    35221 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    35281 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    35341 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    35401 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    35461 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    35521 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    35581 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    35641 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    35701 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    35761 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    35821 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    35881 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    35941 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    36001 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    36061 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    36121 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    36181 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    36241 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaagg
    36301 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    36361 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    36421 gtagaccttt ttgattgcca aaagtgtaag tcgcaccttg atgaccacat aagggactca
    36481 cgacatctgc tagaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    36541 aaacagaagc taagtctaat aaggattgac cggaagcagg caagacattt ccatccctat
    36601 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    36661 caccaacacc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    36721 caataccata agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    36781 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    36841 ctttttgtcc aaaagggtct gtcattttag gtcaagagaa tgtcggatag catctacagt
    36901 accttctccc ccatcaccaa cagggcagag gagatattct acatctgcta tcgattgttg
    36961 gaagcctctt tttattgctt cagctacctg ttgagctgtc aaactttcct taaacgaatc
    37021 tggtgcaatt acaatcttca tattttccct cattctaaac agtcaatcaa aggaagaact
    37081 tctaaaaaat ccctcttgtc aacatgatgt ggtatttctt ttttgagcac ttctttggca
    37141 caaaaggcga ttcctaactc cgccgacttc aacattaata gattattgac cccatcaccg
    37201 attgccaccg ttctttcttt agaaagtttt agtttctttc tccatttttc cagagtctct
    37261 tttttgacct ggggacttat aatttgttca actaattttc ctgttaaaag accttctttg
    37321 acttcaagct ggttggcagt gaaataggca ataccaaggg attttgctaa tctctccaac
    37381 tattggtatc caccagacac cacacaccag accaactagg atgccattct tttggagaat
    37441 agagatgaac tctgggacat ttagcgatag atgaattgag ttgaagacgt tatcaaagac
    37501 caaaatagga agaccttcca acaaggacac tctttttctt aaactgcttt caaagaccaa
    37561 ctctcctcgc attgcccgac ttgtaatctg cgaaatttcc gcctcatgac ctgcctctct
    37621 ccctaaaaga tcaatcactt cttctaggat taaggttcca tctacatcca aaacacacaa
    37681 gccttttact tgagacatca gttctcctct ctaaacagcc taaaaatcgt atgaagtcat
    37741 catacgattt tatctattaa ttaactaaac tatggtacaa gtcaaggtat gacttgcagg
    37801 ctgtatccca tgagaagtca ctctccatag cttgtttttg taggtttctc caaatgtctg
    37861 gatggtttct atacaagtcc aatgctgttt ggaaagtcca atttaaccaa taaggagata
    37921 gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg attgaaagcg cgaactgtat
    37981 ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc ataacgcata gccatcattt
    38041 gagacaagcc acacggttca aaacgacttg gcatgaggaa gaggtcacaa gcagcgtaga
    38101 tttcctgagc aagtttgaca tcaaaagtga tatttgttga tagcttgtct gggtaaatct
    38161 gagcaaacca tgagaaagct ccttcaaagg ctggatcgcc agttcccaaa agaacaatct
    38221 gaacatcttc ttgcaagata tggtgaagac tttcgaccac cacatcaaaa cctttttgac
    38281 gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc tctaacaggc aagccaactc
    38341 tttcttgcaa ttttgcctta tttttggctt tcccagacaa atcttcctga ttgaaatgat
    38401 agtctaaaag agcatccgtc tgaggattat aaagatcagc atcaatccca ttcacgatac
    38461 cagatacttt accagactcc attttaagaa tctgatccaa attacatcca aactgactag
    38521 tcataatttc atgagcatag ctaggtgaaa cggttgaaac acggttcgca tagagaatac
    38581 ctgccttcat ccagttcaga cagttgttcc atcgaagggt gccatcagcg taacgttcaa
    38641 agccaactcc aaacaaatca cccaacattc cttctgaaaa ttgtccttgg aattctaaat
    38701 tatgaatggt taaaactgtt tcaatgtcct cataggcttg aatccaacgg tatttttcct
    38761 tcaacaagaa aggaatcata gctgtatggt agtcatgaac atggagaaga tcaggaataa
    38821 agtcaatcct ttccatagcc tcaatggcag ccagttggaa aaaggcaaag cgttctccgt
    38881 catcaaaatc accgtaaaca tgaccacgga agaaataata ttgattgtca ataaagtaga
    38941 aggttacacc atttaatact gttttcttaa ttccacaata ctgtctgcgc caaccaacgc
    39001 tcacctcaaa atgaagtaca tcttcaatct gatttccaaa tttagcctct accatatcat
    39061 agtagggtaa aatcactgca acttcgtgcc cagcttttac cagtgatttt ggaagagcgc
    39121 caatgacgtc tcccaaacca cctgtttttg aaaagggtgc accctctgct gctacaaata
    39181 aaattttcat gaatgaatat cctctgttac tttagcacct ttcttaacca caactggatg
    39241 ttctgcagtt cctcgaatca caacaccatg ctcaacttca acccctttgt ccaagatagc
    39301 atattcgacc tgagcccctt ctccaataac aacacgaggg aagagcaggc tatctttaac
    39361 caagctatcc ttatggacat gaatattacg tgatagaaca gaattagcta cttgaccttc
    39421 aataatacta ccagaggcaa actgagaagt gcttacctta gatgtattag catagtaagt
    39481 tggctcttcg tttttgacct ttgtataaat cttttggttt ggtgagaaaa gagaatagaa
    39541 tttttgtgat tcaagcatat cgatattcgc ttgataataa gatttaacag agtgaatatt
    39601 ggctagatag cccgtgtact cgtaggcgaa agctccctct tttacagcca aatcccgtaa
    39661 aacatagcga aatttctctg gatgttcttt tttagcttct tcttccaagt gttcaatcaa
    39721 ccaaggtgta tcaacgacaa agatatctgt agacatattg aacgtttcag ctgttgactt
    39781 gctatcaaag agtttatgag aaagaacatg gtctgtttca tctacatcca agattgcatt
    39841 tacttctgaa atatctttct tagctagttt tttataaact acagtgatag gctcttttgt
    39901 tgtactatgt aggtggaaaa cttggttcaa atcaatgtta ataagaacat cgcagttgag
    39961 ggcaaccgtt tggtttgagc cagaacgttt caaataagta agaagctgtt ggtagtattc
    40021 ttttccaact gtactacttt ctacacgggt attgtaaatt cctagatagt aatgactaag
    40081 aagggttgat aagccccact cgcgtcctga acgaatatgg tcaaatactg agctgatatt
    40141 atcctgctgg aaaataccaa agacactacg aacacctgca ttagcaaggc ttgaaagtgg
    40201 gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt gctactggac gatggtctgt
    40261 caatgtcgac atattgtgaa aaccaactgt atttcctaaa atggcagaat atttatcaat
    40321 cttcatctgt tgctaccccc actacttcat tatatcctac aacttgtact tcatctgttc
    40381 catcaatttc gacaccgtca gaaataatcg caccttcacc aataatggca cgtttaatct
    40441 tagctccttg accaatgata gctccactca tgataactga atcaaggact tccgctcctt
    40501 cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac agttccatca acgaaacatc
    40561 cgtctacaac taatgagtct tccacatgag catttgcccc gaggaagttt ggtggtgaaa
    40621 tcaagtttct tgagtaaatc ttccattgac ggttacgact atccaaggca ttttctggag
    40681 aaatatactc catgttcgct tcccaaagtg actcaatagt accaacatct ttccaataac
    40741 cactaaattc gtaagcataa acactttcac ctgactcaag gtaatttgga atgacatttt
    40801 taccaaagtc tgacatgcca accttgctct tttcagcagc gactaacata ttacgaaggc
    40861 gttgccaatc aaaaatgtag attcccatag aagcttttgt agatttaggt tgagctggtt
    40921 tttcttcaaa ttcaacaata cgattgttag catctgtgtt catgatacca aaacggcttg
    40981 cttctttaag agggacgtct aaaactgcta ctgtcaagct ggcattatta tccttatgag
    41041 actggagcat atcatcatag tccattttgt agatgtggtc cccagacaaa atcaagacat
    41101 actcaggatt gacactgtcg atatagtcga tattttggta aatagcgtga ctagttccct
    41161 caaaccaacg atttccttca cttgcagaat aaggttgaag aatagagacg cctgaattaa
    41221 taccgtctag tccccagctt gaaccattcc caatatggtt gttgagagca agtggttgat
    41281 actgtgtaac gaccccaaca ttatgaatcc ctgagttggc acagtttgat agggcaaagt
    41341 caatgatacg gtagcgccca ccaaattgca cagctggttt tgcgatgctt tgagtgagtt
    41401 taccgagacg agttccttgc ccaccagcaa gaatcaaagc taacatttca tttttcattt
    41461 tctactcctt tttggttttt atttgtgacg gttttagtag atttcaagcg acgtttgatt
    41521 ttccatacac ttgctcccat agccggtaga gtaaaggtta aggtctgctc ataatctttc
    41581 cataggcctt cttgcgtttg aacagtttga ttatgttctt tccaaacgcc tccccactct
    41641 tccaactcag tattccatac ttcttcgtaa attcctgcaa cgggtagtcc gattgtaaaa
    41701 tctttccgct caacaggtac catgttaaag atacagacta acatttctcc ctttttaccc
    41761 ttacgaataa aggaaagaac actctggtct cgattatccg catcaatgat ttcaatacca
    41821 tcatagctgg tatcgatttc ccacagacag cgatgatctt tgtaaaactg gtttagctga
    41881 gaagtgaaat acttcatctt agcattcatt gggtcttcta ggttagacca ttccaactgt
    41941 tcttcagatt tccattctag gaattgaccg tattcgctac ccatgaagag caatttctta
    42001 ccagggtgac aaatttggta cgtatagaga ttgcgcaagc ttgcgaattg attgtaacga
    42061 tctccccaca tcttatgcat catactcttc ttgccatgaa ccacttcatc gtgcgagaat
    42121 ggcaagagat aattctcctt gaaaacatac ataaagctga aagtcaccag gttaaagtca
    42181 tatttacgat aaatcggatc ttcttcgtag aaacggagga tatcattcat ccagcccatg
    42241 ttccatttgt agtcaaatcc tagaccacca atctctttca ttcccgtaat cttggtcgca
    42301 gacgaacttt cttctgcaat catcatcaca tctggatatt ctaacttaat aacttcattc
    42361 aagcgttgaa gaaaataata accttcatag ttgagatttc cgccatcttt attaggtgtc
    42421 catggagcat tatcatagtc caaatagagc atgttgctaa cagcatccac acgaatacca
    42481 tccaaatgat agacatcaat ccaatgctta atgcaagaaa ttaagaagga ctggacttca
    42541 ttttttccaa ggtcaaaatt aagggcaccc caaccatggt tatgagcctt attatggtct
    42601 tggtattcaa aagtcggtgt cccatcataa taggctaagg catcatcgtt gatggtaaag
    42661 tgacctggta cccagtccac aataacccca atattatggg tatgacactc ctcgacaaaa
    42721 tcttgaaact cctctggtct gccataagca tgctctaaag cgaagtaacc cataagctga
    42781 tacccccaac tcaagcccaa aggatgggac atcaagggca taaactcaat atgagtatag
    42841 ttcatttcaa cgagataagg aatgagttca tccttgagct gggcaaaact ataaggactg
    42901 ccatcagaat ttcttttcca tgatccagcg tgaacttcat aaatattgac aggacgctct
    42961 tcaaagcccc aacgttttct tcgtgccagc caaagtccat ccttccattt cttctcagga
    43021 agctctgtta agattgcccc tgttcctgga cgagcctcat acctgacagc aaaagggtca
    43081 atcttcatca gttgatgacc attttgacgt gtgacatgat atttgtaaat atgcccttct
    43141 tgagccatat tggtaaagac ttcccagacc ccaaaatcat ttcttaccat tggaatctga
    43201 ttttcaatcc agttggtaaa atcaccaacc aagtgaacag cctgagcatt aggtgcccaa
    43261 acacggaagg tatagccatg ctctccattt agttcttccc tatgtgctcc tagataatgt
    43321 tggagataaa aattttcacc cgtcataaag gtttttaatg cttctctatt atccatatac
    43381 tccccttctc ctgtaagcgt tttctatgtt tttattatac taccttttta gagaagattc
    43441 aagtaaatta ctatacttct ttaattattt tgaaaatcta caacaagttc acttactcgt
    43501 tcaattgtaa atcaatattt tttcaaaaaa ttgcgaaaac gcctttcttt ttctactata
    43561 gtgaaatgaa ataaaacatg cgcaaatcga ttaaggaatt taatctaatt tctaacaatg
    43621 t
//
LOCUS       DBEJNA010000015        43053 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEJNA010000015 DBEJNA010000000
VERSION     DBEJNA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.15"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            22..95
                     /locus_tag="ACL3JB_000924"
     tRNA            22..95
                     /locus_tag="ACL3JB_000924"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56..58,aa:Ile,seq:gat)
     gene            102..189
                     /locus_tag="ACL3JB_000925"
     tRNA            102..189
                     /locus_tag="ACL3JB_000925"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:136..138,aa:Ser,seq:gct)
     gene            complement(315..1250)
                     /gene="birA"
                     /locus_tag="ACL3JB_000926"
     CDS             complement(315..1250)
                     /gene="birA"
                     /locus_tag="ACL3JB_000926"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0685683.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1247..2107)
                     /locus_tag="ACL3JB_000927"
     CDS             complement(1247..2107)
                     /locus_tag="ACL3JB_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0685684.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2215..4377
                     /locus_tag="ACL3JB_000928"
     CDS             2215..4377
                     /locus_tag="ACL3JB_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0685685.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4469..5728
                     /locus_tag="ACL3JB_000929"
     CDS             4469..5728
                     /locus_tag="ACL3JB_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0685686.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5742..6608
                     /locus_tag="ACL3JB_000930"
     CDS             5742..6608
                     /locus_tag="ACL3JB_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0685687.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6622..7455
                     /locus_tag="ACL3JB_000931"
     CDS             6622..7455
                     /locus_tag="ACL3JB_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0685688.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAIMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7766..9208
                     /gene="gtfA"
                     /locus_tag="ACL3JB_000932"
     CDS             7766..9208
                     /gene="gtfA"
                     /locus_tag="ACL3JB_000932"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0685689.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYALNEFYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9346..10539
                     /locus_tag="ACL3JB_000933"
     CDS             9346..10539
                     /locus_tag="ACL3JB_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0685690.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11224..13203
                     /locus_tag="ACL3JB_000934"
     CDS             11224..13203
                     /locus_tag="ACL3JB_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0685691.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13270..14766
                     /locus_tag="ACL3JB_000935"
     CDS             13270..14766
                     /locus_tag="ACL3JB_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685692.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14766..15692
                     /gene="oppC"
                     /locus_tag="ACL3JB_000936"
     CDS             14766..15692
                     /gene="oppC"
                     /locus_tag="ACL3JB_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0685693.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15701..16768
                     /locus_tag="ACL3JB_000937"
     CDS             15701..16768
                     /locus_tag="ACL3JB_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685694.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIVQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16779..17705
                     /locus_tag="ACL3JB_000938"
     CDS             16779..17705
                     /locus_tag="ACL3JB_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685695.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18195..19133
                     /locus_tag="ACL3JB_000939"
                     /pseudo
     CDS             18195..19133
                     /locus_tag="ACL3JB_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate binding protein"
     gene            19145..20034
                     /locus_tag="ACL3JB_000940"
                     /pseudo
     CDS             19145..20034
                     /locus_tag="ACL3JB_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20047..20850
                     /locus_tag="ACL3JB_000941"
     CDS             20047..20850
                     /locus_tag="ACL3JB_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685696.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSMDEGDLLLAGKSIKNLSVRKRAKDIARVFQAPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQLTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLR"
     gene            complement(20882..21592)
                     /gene="treR"
                     /locus_tag="ACL3JB_000942"
     CDS             complement(20882..21592)
                     /gene="treR"
                     /locus_tag="ACL3JB_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0685697.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21777..23744
                     /gene="treP"
                     /locus_tag="ACL3JB_000943"
     CDS             21777..23744
                     /gene="treP"
                     /locus_tag="ACL3JB_000943"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0685698.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23922..25547
                     /gene="treC"
                     /locus_tag="ACL3JB_000944"
     CDS             23922..25547
                     /gene="treC"
                     /locus_tag="ACL3JB_000944"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0685699.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25803..26051
                     /locus_tag="ACL3JB_000945"
     CDS             25803..26051
                     /locus_tag="ACL3JB_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0685700.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26258..27052
                     /gene="racE"
                     /locus_tag="ACL3JB_000946"
     CDS             26258..27052
                     /gene="racE"
                     /locus_tag="ACL3JB_000946"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0685701.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27049..28020
                     /locus_tag="ACL3JB_000947"
     CDS             27049..28020
                     /locus_tag="ACL3JB_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0685702.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27996..28517
                     /locus_tag="ACL3JB_000948"
     CDS             27996..28517
                     /locus_tag="ACL3JB_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0685703.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28514..28975
                     /gene="cbpB"
                     /locus_tag="ACL3JB_000949"
     CDS             28514..28975
                     /gene="cbpB"
                     /locus_tag="ACL3JB_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0685704.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28972..29706
                     /gene="xerD"
                     /locus_tag="ACL3JB_000950"
     CDS             28972..29706
                     /gene="xerD"
                     /locus_tag="ACL3JB_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0685705.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29706..30434
                     /locus_tag="ACL3JB_000951"
     CDS             29706..30434
                     /locus_tag="ACL3JB_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0685706.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30453..31022
                     /gene="scpB"
                     /locus_tag="ACL3JB_000952"
     CDS             30453..31022
                     /gene="scpB"
                     /locus_tag="ACL3JB_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0685707.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31009..31731
                     /locus_tag="ACL3JB_000953"
     CDS             31009..31731
                     /locus_tag="ACL3JB_000953"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0685708.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31731..31973
                     /gene="yidD"
                     /locus_tag="ACL3JB_000954"
     CDS             31731..31973
                     /gene="yidD"
                     /locus_tag="ACL3JB_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0685709.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPIPDHFSLKRNQEGE"
     gene            complement(32198..33163)
                     /locus_tag="ACL3JB_000955"
     CDS             complement(32198..33163)
                     /locus_tag="ACL3JB_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0685710.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33259..34011)
                     /locus_tag="ACL3JB_000956"
     CDS             complement(33259..34011)
                     /locus_tag="ACL3JB_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685711.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34008..34964)
                     /locus_tag="ACL3JB_000957"
     CDS             complement(34008..34964)
                     /locus_tag="ACL3JB_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0685712.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFVLLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFSFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34954..35913)
                     /locus_tag="ACL3JB_000958"
     CDS             complement(34954..35913)
                     /locus_tag="ACL3JB_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685713.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGDLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36210..36320)
                     /locus_tag="ACL3JB_000959"
     CDS             complement(36210..36320)
                     /locus_tag="ACL3JB_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0685714.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(36336..37037)
                     /locus_tag="ACL3JB_000960"
     CDS             complement(36336..37037)
                     /locus_tag="ACL3JB_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0685715.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SHASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTTNVAGMNQV
                     LKVLSEVGIQKIMFSSTASLCGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37438..38502
                     /gene="pepA"
                     /locus_tag="ACL3JB_000961"
     CDS             37438..38502
                     /gene="pepA"
                     /locus_tag="ACL3JB_000961"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0685716.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38524..38820
                     /locus_tag="ACL3JB_000962"
     CDS             38524..38820
                     /locus_tag="ACL3JB_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0685717.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39502..39945
                     /locus_tag="ACL3JB_000963"
     CDS             39502..39945
                     /locus_tag="ACL3JB_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0685718.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39949..40713
                     /locus_tag="ACL3JB_000964"
     CDS             39949..40713
                     /locus_tag="ACL3JB_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0685719.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40728..41456
                     /locus_tag="ACL3JB_000965"
     CDS             40728..41456
                     /locus_tag="ACL3JB_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0685720.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41449..42969
                     /locus_tag="ACL3JB_000966"
     CDS             41449..42969
                     /locus_tag="ACL3JB_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0685721.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENVIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12477 a         7982 c         9666 g        12928 t
ORIGIN      
        1 aattaccaag ttttttaact tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa
       61 gcgtgaggtc ggtggttcga gtccactcgt gcccattaat tggagaatta ctcaagaggc
      121 tgaagaggac ggtttgctaa atcgttaggt cgggtaactg gcgcaagggt tcgaatccct
      181 tattctccgt tttaatgaga gtttgtaact ctctttttta tttttagagc caataaaact
      241 tcagatccgt aaaacttaat tgaattacta atctgaagtt atttttatat cgtttatatt
      301 ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt tagccagatt
      361 tcttttccgt tatcacattg aactaaaagt tttccatttt ctgagatgtc tttagcaagt
      421 cccttgtagt ctttttgctc tagtgtgaaa gtgacttctt ttcctagaat gaatgactgt
      481 tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg ccagatttct
      541 atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc agctttttct
      601 tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat aatgatatct
      661 gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc aattttatga
      721 ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt taggttctta
      781 atggctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt gtcatagggg
      841 agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta gaaggaacgt
      901 tgaaaacggc ctcggcctgc tgtttgatag gaagctagat agagggtatt tgcttcatgg
      961 cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg tttaaagctg
     1021 actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc attcatcagt
     1081 ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag tcgcttgatg
     1141 gctttccaaa ttgctgttcg gcttagggat agtttttctg cgattttttc tccgctgata
     1201 tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat aatgttgcct
     1261 ttcttactag ttggtattga gagtattctt ttcttgtatg acttggagtc tgattaaagt
     1321 attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag tatgcaatta
     1381 ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt cgaacgtaga
     1441 gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat aagtagcttc
     1501 tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga tagtggctat
     1561 caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc ttttttttct
     1621 gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc atgatatgga
     1681 gttgagctaa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct gagatgagtt
     1741 ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga tcagaaattt
     1801 gggaaagagc aaaataatca ggggctttcc ctccagtgat tcctaaccag tagtaggccc
     1861 aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat agaaagaaat
     1921 ctccttcttt taaatcaaca attttaccct tgtaatgaaa ttttccttgt cctttagtaa
     1981 tgtaatgtag aacgtatgta tcacgaatgg ctggaccaaa agagtaatta ggtgtgcatt
     2041 cctcatatcc ataaaagctt agggcaaggt cgattgttcc agtctggtat tctgaaaaaa
     2101 ctaacatgtg ctacctccta cctaacattt taccatattc ttgagacatt tttctatttt
     2161 ggaaagcgat ttcaggtgat aaaatataat caataaagtg atgaggtgaa gtaaatggga
     2221 gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt gattattgaa
     2281 aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa ctataaaggt
     2341 tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacggc tactaatcga
     2401 acctttagtt tagatactca gcgacagatt tttggacaac atggcttagg agattttagg
     2461 aaaccaacca tacaggttca gcatagtgta actgaagtaa cagactttcg atttgtagaa
     2521 gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca tagcatggac
     2581 gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag tctgactttg
     2641 tattatacta cttttaataa tgatgcgact attgctagct acagtaaatt agataataat
     2701 agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt tccagctgca
     2761 gattacgaaa tagtaactct gcagggtgct tatgctcgtg aaaagactgt tagacgtcaa
     2821 caggtagaac aaggaatctt ttcgattagc tcaaaccgag gtgcttctgg tcatgctcaa
     2881 acaccagctc ttctactatg cgaacaagga gtcacagagg atgctgggaa tgtgtttgct
     2941 attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca attgaatgaa
     3001 gttcgggtgg ctattggcat taatccagaa aacttttctt ggaagttagc ccctgaggaa
     3061 tactttgaaa caccggtagc tttagtgact cattcagatc agggattaac tggtattagt
     3121 catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc taaaaaagaa
     3181 cgtccaattc taatcaataa ctgggaagct acttactttg actttcagag agaaaaactg
     3241 ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt agatgatggt
     3301 tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt taatgaggaa
     3361 aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg tttgcagttt
     3421 ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg tcaacatcct
     3481 gactgggcta ttcaggttcc tgattatgag catacttatt ctcggaatca attagtactt
     3541 aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca actcctatct
     3601 tatcatgaga ttgattacat taaatgggat atgaaccgca atatcactaa gctagggaat
     3661 ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg actttacgaa
     3721 ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg ctctggtggt
     3781 ggtggacgaa atgatcttgg tatgatacgc tatttcccac aagtctgggc tagtgataat
     3841 actgatgcca ttgcacgttt accaattcaa tacggttcat cctatctcta tccaaccatt
     3901 tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat gacaccatta
     3961 gaaacacgtg gccatgtagc aatgatggga aatttgggct atgagcttga tttgacaaat
     4021 ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa agaattacga
     4081 ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgc atccaatgaa
     4141 gcagctgtac aatttaatta cggaaatcaa acgattgtaa cctacgttcg cgttttatct
     4201 gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga gggactatat
     4261 aaattacagg aaaatggcga agtttactca ggtgcagaac taatgtatgc gggcttaact
     4321 gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa actatgatat
     4381 gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt tcaataaggg
     4441 tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg gacttcttgc
     4501 aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta aatctgcgga
     4561 tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga
     4621 aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc
     4681 aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa
     4741 tatttaccca cagtccatcg aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt
     4801 gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa
     4861 cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact acaacaaaga
     4921 taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg aacagttagt
     4981 caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag atgcttggac
     5041 actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa
     5101 tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga ttatgaaaga
     5161 tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga actgggaagg
     5221 tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa
     5281 tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga ttgggacctt
     5341 catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag acttggcatg
     5401 gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg aatatatgac
     5461 ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag cgatcgaagg
     5521 ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg cctttacgga
     5581 tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc ataccttgac
     5641 catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga atgccttctt
     5701 taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa gtattacaaa
     5761 aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg
     5821 tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg acttataact
     5881 acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa ttcatgaatg
     5941 cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt gcactcggga
     6001 tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc cgtgcttggt
     6061 tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag caagtcttca
     6121 actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa accagtcttt
     6181 tagggactaa gtggggagca atctttgcgg ctgcctttgt ccttctttgg caaggggtgg
     6241 ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag attacagagg
     6301 cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa ttgccttact
     6361 tgctaccaag tgtctctatg gtctttatcc tagccctaaa aggtgggctg actgcctttg
     6421 accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca cttgggctct
     6481 tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc attgccgtaa
     6541 tcttgttcct cttaattgta gtgatttcga tcatccaatt gagagtatct aagaaatttg
     6601 aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat tggcaaatac
     6661 attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac cctctttagt
     6721 tccttcaaac ccactaagga tattgtagat aatttctttg gctttccaac caacttcaca
     6781 tgggacaact ttagccgtct cttagctgat gggattggag gctattattg gaactctgtc
     6841 gtcatcactg tcttgtcttt acttgcaata atgatcttta tccctatggc agcctactcc
     6901 atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct cttaatcctc
     6961 ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat gagtaaactc
     7021 ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat tccacagacc
     7081 ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga tgaagcagca
     7141 gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc aatgatgaaa
     7201 ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga cttcatgttg
     7261 ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt ccaatacaac
     7321 tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt ggtcggcatt
     7381 atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg aatgagcaac
     7441 ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc
     7501 tgtacttgag tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtataa
     7561 gaagagctca tggaatctat agtctttgac acagaggaag agttcagctt gttgataatt
     7621 ctatgtagaa aacaagaaag tagtactttg tttatcacag tctatattag tacgagtttg
     7681 atgataaata gagatttaaa atgaatttta tttatgaagc cagatcatat gagacttggc
     7741 ttcaattaga aaaaggagag taatgatgcc aattcaaaat aaaaccatgt tgattaccta
     7801 ttctgatagc cttggaaata atcttaaaga cttatatgat aatttggaag agcattttgg
     7861 agatgctatt ggaggagttc accttttacc atttttccca tcaacaggtg atcgtggatt
     7921 tgcgccagtt gactacgacg aagtggactc agcttttggt gattgggagg atgttaagcg
     7981 tttaggtgag agatattatc ttatgtttga ttttatgatt aatcatattt ctcgtcaatc
     8041 caagtattat aaggactatc aagaaaaaca tgaagccagt gaatttaaag atctcttttt
     8101 aaactgggat aagttttggc cagaaaaccg tccgacacag tctgatgtag atttaattta
     8161 caagcgtaag gatcgtgcac caaagcaaga gattgtgttt gaagatggtt cagtggaaca
     8221 tttgtggaat acctttggtg aggagcagat tgatcttgat gtgaccaaag aagtaactat
     8281 ggaatttatc cgtaagacca ttcagcactt ggcaagtaat gggtgtgatt tgattcgtct
     8341 agatgccttt gcttatgcag tgaagaaatt ggatactaat gatttctttg tggaaccaga
     8401 tatttgggat ttattggaca aagttcgaga tatcgctgct gagtatggga cagagctttt
     8461 acctgagatt catgaacact attcgattca gtttaaaata gcagaccatg attactatgt
     8521 ttatgatttt gctcttccaa tggtgacact ttatactctt tacagttcca gaacagagcg
     8581 tttggctaag tggttaaaga tgagcccgat gaagcaattt acgacgctag atacccatga
     8641 tgggattgga gtagtagatg tcaaggatat cctgaccgat gaggagattg actatgcttt
     8701 aaatgaattc tataaggttg gagccaatgt caaacgtaag tactctagtg ccgagtataa
     8761 caacttagat atctaccaaa tcaattcaac ctactattca gcgcttggag atgatgatgt
     8821 caagtatttt ctcgctcgtc taattcaagc ttttgcccca ggtattcctc aggtttacta
     8881 tgtgggtcta ttagcaggca agaatgactt gaaattatta gaagaaacta aagaaggtcg
     8941 aaatattaat cgtcattact atagcaacga ggaaatagca aaagaagtgc aacgacctgt
     9001 tgtgaaggcc cttctcaatc tattttcttt ccgtaaccgt tcagaagcct ttgatctaga
     9061 agggactact gagatagaga caccaacagc tcacagcatt gtaatcaaac gtcaaaataa
     9121 agataagtcc gtaacagcag tagcagaaat tgatttgcaa aatcagactt atcgggtaat
     9181 tgagaatgga gttgaagtaa cattttgaag ccttgatatg gtggataaaa tagggttttt
     9241 attttggaaa acgtttcctt tgttttcaaa ttgctaaaaa agtggtacaa tataggatag
     9301 cttactatta tctgaatcag ctgatttgga gagaaaggat tcattttgaa atcaataggc
     9361 tttattgaaa agctgaaggg gttgtctagt aaagagctga ttttattggg aattatcctg
     9421 agtatctttt taccctttta tctttttgta gttgtactct gtttatatat tatcagtttg
     9481 atttttacag gagacatgaa aagtattctt cagaaaatgg gggagcatcc gatgctgctt
     9541 ctttttctta gctatagtac tgttatatcc attcttgcac aaaattggat gggtcttgtg
     9601 gcttcagtag gaatgtttct atttactatt ttctttttgc actatcagtc gattttatcc
     9661 cataaattct ttcgattgat tttgcagttc gtcttgtttg gtagtgtctt gtcagctgct
     9721 tttgccagtt tagaacattt ccaaattgtg aagaaattta actatgcttt tctttcaccc
     9781 aatatgcagg tgtggcatca gaaccgggca gaagtgacct tctttaatcc taattattat
     9841 ggaattattt gttgtttctg tattatgatt gctttctatc tgtttacaac gaccaagttg
     9901 aattggttga aagtattctg tgtgattgca ggctttgtta atctctttgg tttgaacttt
     9961 actcaaaatc gaactgcctt tcctgctatt atcgctggag caattatcta tctctttacg
    10021 actattaaaa actggaaggc tttttggctt agtattgggg tcttcgcgat tggtttgagt
    10081 ttcctctttt ctagtgattt gggagttcga atgggtactt tagactcttc tatggaagaa
    10141 cgcatttcta tctgggatgc tgggatggcc ttgtttaagc aaaatccttt ttggggtgaa
    10201 gggccattga cctatatgca ctcttatcct cggatacatg ctccttatca tgaacatgcc
    10261 cacagtcttt atattgatac gattctgagt tacggaattg tgggtaccat tttattagtt
    10321 ctgtcttctg ttgctcctgt tcgtttgatg atggatatga gtcaggagtc ggggaaacgt
    10381 ccgattatcg gcctttatct atctttcctt acagtggttg ctgtgcacgg aatttttgac
    10441 ttggctctct tctggattca gtcaggcttt attttcttgc tagttatgtg cagtattcca
    10501 ttggagcatc gaatgttggt atcggacatg acggattaag ttttataagt ttgaaatctt
    10561 ctaccttggg taggagattt tttatacgat gggcatgtcg tgcatctgag gtgtaagtcc
    10621 tctgtaggga tccactaccg gtgaatacaa tagcgctccc caagcctgac tatcgtgagg
    10681 tagcggatta aaatggtctg gggatagatc gttttaagtc tgacgcagga aataagaatt
    10741 gtcagagaaa gcaatagtga aatcgtaggc tatgaataga aacgtgatag cgaggagcat
    10801 atagtggaca aggtagcgag aaattttaaa gtataaaaga tagtcttaat ctatatgtgt
    10861 aaatcacgaa agtaattgaa ttcggaataa ggttggtgtg aaaagacata gtaaactgaa
    10921 tcttgaatac tagaatgata cttctacaat attgttataa tttaatttga attccaaaat
    10981 cacattgttc cgtccgtatt tcattttact gtatgtcttc ctaagctcca aaatttctgt
    11041 gtcaaatttc ctattttcac tgtagtcttt gacacttcga acgacaattt gaatcatata
    11101 ttcaaaaaaa atgaaaaatt tgtgccaaca agcctaaata ttctgaaaat ttgtttgatt
    11161 tttaatggat aatgtgatat aatggttgtc aatctataat tcacataaac agaggagtag
    11221 aaaatgaaaa aaaatcgtgt atttgctaca gcaggtcttg ttttattagc agcaggtgta
    11281 cttgcagcat gcagttcttc aaaatcatct gattcatcag cccctaaagc ttatggctat
    11341 gtttatacag cagacccaga aaccttggac tacctgattt caagtaaaaa tagtacaaca
    11401 gtagtgactt caaatgggat tgatggttta ttcactaacg ataattacgg taatcttgct
    11461 cctgcagttg cagaggattg ggaagtctct aaggatggtt tgacctacac ttataagatt
    11521 cgtaaagggg ttaaatggtt tacctctgat ggagaagaat atgcagaggt gacggctaaa
    11581 gatttcgtga acggtttaaa acacgcagca gataaaaaat cagaagctat gtatttagct
    11641 gaaaattcgg ttaaaggctt ggcagattat ctatcaggaa cttcaacaga tttttcaaca
    11701 gttggtgtca aggcggttga tgattatacg ttacaataca ctttgaacca gcctgaaccg
    11761 ttctggaact ctaagttgac ctattctatt ttctggcctc tgaatgaaga attcgaaaca
    11821 tcaaaaggaa gcgattttgc taaaccaaca gatccgacat ccttgcttta taatggtcca
    11881 ttcttgttga aagggttgac tgcaaaatct tctgtagagt ttgtaaaaaa tgagcaatat
    11941 tgggataaag aaaatgtcca cctagatact atcaatctag cttactatga tggatcagat
    12001 caggagtcgc tagagcgtaa cttcactagt ggagcttata gttatgcccg tctttaccct
    12061 accagctcca actattctaa ggttgcagaa gaatacaagg acaatatcta ttacacacaa
    12121 tcaggctctg ggattgctgg tctgggtgtg aatattgatc gccaaagtta caactatact
    12181 tctaaaacta cagattcaga gaaagtagct actaagaagg cattgcttaa caaagatttc
    12241 cgtcaagcct tgaattttgc tcttgatcgc tcagcttact cagctcaaat caatggtaaa
    12301 gatggagcag ctttagcagt tcgtaattta tttgtaaaac cagactttgt ttcagctggt
    12361 gagaagacct ttggtgattt agtcgctgct caacttcctg cttatggtga tgagtggaaa
    12421 ggtgtgaatt tagctgatgg gcaggatggt ttattcaatg ctgacaaggc caaggcagag
    12481 tttgcgaaag ctaagaaagc tttagaagca gacggcgttc agtttcctat tcatctggac
    12541 gttccagtag accaagcatc aaaaaactat atatctcgta ttcagtcctt taaacaatct
    12601 gtagaaacag ttcttggtgt tgaaaatgtc gttgttgata ttcaacaaat gacaagtgat
    12661 gaattcctta atattactta ctatgctgcc aatgcttcat ctgaggattg ggatgtatcg
    12721 ggaggagttt catgggggcc agactatcaa gacccatcta cttacctgga tattttaaaa
    12781 acaactagca gtgaaactac aaaaacatat ttaggatttg ataatccaaa tagcccttca
    12841 gtagttcaag ttggtttgaa agaatacgat aaattagttg atgaagctgc caaagagaca
    12901 agcgacttga atgtccgtta tgaaaaatat gcagcggctc aagcatggtt gacagatagt
    12961 tcactcttta ttcctgctat ggcttcttct ggtgcagcac cagtgctttc acgaattgtt
    13021 ccatttactg gagcttctgc gcaaacaggc tctaaggggt cagatgttta cttcaaatat
    13081 ttgaaattac aagataaagc ggtgactaag gaagagtatg aaaaagctcg tgaaaaatgg
    13141 ttgaaagaaa aagctgaatc aaatgagaaa gctcaaaaag aattggcaag tcatgtgaag
    13201 taaataattt ctaatagaac tttctctcca tgaggagaag gttcttttgg gatttttaaa
    13261 ggaaataata tgaaaaaata tatttttatg cgtgttttgc ggtcattggt ttcgattttc
    13321 ttagtaacga ctttgaccta cacgattatc tataccttgg ttcctcgaaa attgattttc
    13381 aagcaggatc ctaactataa taaaattgcg acaacggctg ataaacgtga taactatgaa
    13441 aatactgtgt ttgagcgtat gggctacatt gagtattacg atactaaaga gttgcaagaa
    13501 aaggcaagta gcatggattc ttctgtaaca gtagaagcaa atgcgaccaa taaagctatt
    13561 tatgaaaagt acatcaatca attaggtcat ggttggactt tgggagaatt tactgaaagt
    13621 ggtcaattct atgctactcg tgaaattcca atttttgaac gtgtttttca cttctatgct
    13681 aacttgattg acattgacca tacaaataaa atccaagacc ctgaaaatcc agacttgaaa
    13741 cgctaccttc gttttgaaaa tgatccagct atcggatggt cattggtcgg ttcaggaact
    13801 aaacataaat atctcttgta ctttaacagt cagttcccat ttgttcatca aaactttgtg
    13861 aacttgaatt taggtgactc ttacccaacc tatgctaata caccagttct tcaggttatt
    13921 actcaaggtc aaggacaaac caaaactgcc caagttcagt tcccaacagg taagaaaacg
    13981 tcttctgtaa atatttactc aagaacctac aagtcaccta gtcaggctga ctctcgtgaa
    14041 gtagctagct atgggaaaga tgatccttat acagcgactg aaagtaatta ccaatatcca
    14101 tctatgattg tcagctctgc tattactggt ttgattggtt tggttcttgc ctatgctctt
    14161 gccgtgccac ttggttcagc catggctcgt ttcaagaaca cttggattga tagcctctca
    14221 acaggggctt tgaccttctt gcttgctctt ccaacgattg ccttggttta catcgttcga
    14281 ttgattggat catctattgc ccttccagat tcattcccta tcttgggagc tggagattgg
    14341 cgttcttacg ttttaccagc agtcatcctt ggtttgttgg gtgctcctgg tacagccatt
    14401 tggattcgtc gttacatgat tgacttgcaa tctcaagact ttgttcgttt cgctcgtgca
    14461 aaaggtttgt ctgaaaaaga aatttcaaac aaacacatct ttaaaaatgc catggttccg
    14521 ctggtttcag gaattcctgg tgccatcatt ggggttatcg gtggtgcaac ccttactgaa
    14581 acagtcttcg ccttcccagg tatgggtaaa atgttgattg actctgtaaa agcatctaat
    14641 aactctatgg tcgttggtct tgtcttcatc tttacatgta tttctatctt ctcacgtctt
    14701 ttgggagata tttggatgac tattattgac ccacgtatta aattgactga gaaaggaggc
    14761 aaataatgtc tacaatcgat aaagaaaaat ttcagtttgt aaaacgtgac gattttgcct
    14821 ctgaaactat tgatgcgcca gcatattctt actggaaatc agtgtttaaa caatttatga
    14881 agaaaaaatc aactgtagtc atgttgggaa tcttggtagc catcattttg ataagtttca
    14941 tctacccaat gttttctaag tttgatttca atgatgtcag caaggtaaac gactttagta
    15001 ttcgttatat caagccaaat gcggagcatt ggttcggtac tgacagtaac ggtaaatcgc
    15061 tctttgacgg tgtctggttc ggagctcgta actccatcct catttctgtg attgcgacag
    15121 tgattaactt ggttatcggt gtttttgtcg gtggtatttg gggtatttca aaatcagttg
    15181 accgtgtcat gatggaagtt tacaacgtca tctcaaacat cccacctctt ttgattgtta
    15241 ttgtcttgac ttactcaatc ggagctggat tctggaatct gatttttgcc atgagcgtaa
    15301 caacatggat tggtatcgcc ttcatgatcc gtgtgcaaat cttgcgctat cgtgacttgg
    15361 aatacaactt ggcgtcacgt actttgggaa caccaacctt gaagattgtt gccaaaaata
    15421 tcatgcctca attggtatct gttattgtga caaccatgac tcaaatgctt ccaagcttta
    15481 tctcatacga agccttcttg tctttcttcg gtcttggatt accgattaca gtgccaagtt
    15541 tgggtcgttt gatttcggat tattcacaaa acgtaacaac caatgcttac ttgttctgga
    15601 ttccattgac aacccttgtc ttggtatcct tgtccctttt cgtagttggt caaaacttag
    15661 cggatgctag tgatccacgt acacatagat aggagtagaa atgacaaaag aaaaaaatgt
    15721 aattttgact gctcgcgata ttgtcgtgga atttgacgtt cgtgacaaag tattgacagc
    15781 cattcgcggc gtttcccttg aactagttga aggagaagta ttagccttgg taggtgagtc
    15841 aggatcaggt aaatctgttt tgacaaagac cttcacaggt atgctcgaag aaaatggtcg
    15901 cattgtccaa ggtagtattg actaccgtgg tcaggatttg acagctttat cttctcacaa
    15961 ggattgggaa caaattcgtg gtgctaagat tgcgactatc ttccaggacc caatgactag
    16021 tttggacccc attaaaacaa ttggtagtca gattacagaa gttattgtaa aacaccaagg
    16081 aaaaacagct aaagaagcga aagaattggc cattgactac atgaataagg ttggcattcc
    16141 agacgcagat agacgtttta atgaataccc attccaatat tctggaggaa tgcgtcaacg
    16201 tatcgttatt gctattgccc ttgcctgccg acctgatgtc ttgatctgtg atgagccaac
    16261 aactgccttg gatgtaacta ttcaagctca gattattgat ttgctaaaat ctttacaaaa
    16321 cgagtatcat ttcacaacaa tctttattac ccacgacctt ggtgtggtgg caagtattgc
    16381 ggataaggta gcggttatgt atgcaggaga aatcgttgag tatggaacgg ttgaggaagt
    16441 cttctatgac cctcgccatc catatacatg gagtctcttg tctagcttgc ctcagcttgc
    16501 tgatgataaa ggggatcttt actcaatccc aggaacacct ccgtcacttt atactgacct
    16561 gaaaggggat gcttttgcct tgcgttctga ctacgcaatg cagattgact tcgaacaaaa
    16621 agctcctcaa ttctcagtat cagagacaca ttgggctaaa acttggcttc ttcatgagga
    16681 tgctccaaaa gtagaaaaac cagctgtgat tgcaaatctc catgataaga tccgtgaaaa
    16741 aatgggattt gcccatctgg ctgactagga ggaaggaaat gtctgaaaaa ttagtagaaa
    16801 tcaaagattt agaaatttcc ttcggtgaag gaagtaagaa gtttgtcgcg gttaaaaatg
    16861 ctaacttctt tatcaacaag ggagaaactt tctcgcttgt aggtgagtcc ggtagtggga
    16921 aaacaactat tggtcgtgct atcatcggtc taaatgatac aagtaatgga gatatcattt
    16981 ttgatggtca aaagattaat ggtaagaaat cgcgtgaaca agctgcggaa ttgattcgtc
    17041 gaatccagat gattttccaa gaccctgccg caagtttgaa tgaacgtgcg actgttgatt
    17101 atattatttc tgaaggtctt tacaatcacc gtttatttaa ggatgaagaa gaacgtaaag
    17161 agaaagttca aaatattatc cgtgaagtag gtcttcttgc tgagcacttg actcgttacc
    17221 ctcatgaatt ctcaggcggt caacgtcaac gtatcggtat tgcccgtgcc ttggtcatgc
    17281 aaccagactt tgttattgca gatgagccaa tttcagcctt ggacgtttct gtacgtgccc
    17341 aagtcttgaa cttgctcaaa aaattccaaa aagagctcgg cctgacctat ctcttcatcg
    17401 cccatgactt gtcggttgtt cgctttattt cagatcgtat cgcagttatt tacaagggtg
    17461 ttattgtaga ggttgcagaa acagaagaat tgtttaacaa tccaattcac ccatatactc
    17521 aagccttgct ttcagcggta ccaatcccag atccaatctt ggaacgtaag aaggtcttga
    17581 aggtttacga tccaagtcaa cacgactatg agactgataa gccatctatg gtagaaatcc
    17641 gtccaggtca ctatgtttgg gcgaaccaag ccgaattggc acgttatcaa aaaggactaa
    17701 actagtaatg gttttataat ttccatgtca atttttatgg aaattataaa actttttttg
    17761 ttggactgat ttgaaaaact ttgaaagctt cctgaaagaa tttttgaaaa attttaaaaa
    17821 ttatgaaata ttattgacag gtgacgaaaa aggtggtagg ataggaagca tcaaaaaaga
    17881 aagcagaaaa agaaatgaat aagagacaag ccgtaactat gaatcaaaac ttttacttta
    17941 gctactttag atagtgtttg tagacatgtc accatggatg caaacagttc aagcaatttg
    18001 tttgtatcta tgtggctaag atttttgatt gtggtccata tagatgaata tctaaatgga
    18061 ctagctaagt tgtaacttgt taggttattt caagtatccg tttagatagt atctaggcgg
    18121 ttttttgttt tatcttttct gagaaggagt ttcattatga aagttgttcg aaaatcacta
    18181 gccccctctt ggtagtgggg atcctcttga cttctctgat cagtttgcat cagttgaagg
    18241 cagataagaa aagagatgtc tttcgtatcg gtatttcgca gtttattacc caccagtcct
    18301 tagacgctac tagagaagga tttgtggatg agctggccaa acaaggctat gttgaggggg
    18361 aaaatattga gattgatttg caaaatgcac agggagaaca aagaaatcta aaaacgattt
    18421 cccagcaact agcagaatcc agcgatgtcg ttctagccat cgcaaggcct tctgctcaga
    18481 gcttggccaa tacgacgcaa acgacaccag ttatcttttc agctgtaaca gacccagtca
    18541 gtgccaagtt ggttgagtca agagaacatc ctgggggcaa tgtaactggg acaagcgatc
    18601 agtcatcaga tgccatttca acccaaatca atttgataaa gaaagtgttg ctaaaggcta
    18661 aaacgattgg aatcctctat actcagagcg agcccaattc ggttgtttaa aaggatgaag
    18721 ctaagcgact tctgaaagaa aaaggcttta ccgttgttga aaaaacaatc ttggacagta
    18781 ataacatcaa ggcggcagca gagagtttga tggcagaggt ggatatggtt tttgtcccaa
    18841 ctgataatat catttcgtca accatggaaa cagttaagca ggtttctatt aaacacaagg
    18901 ttccagtatt cggtggttca acagaaatga ttgctgttgg tgacttgtat aactacggaa
    18961 ccaattatga agaattggga agacagacag ctcgcatgct gattcgtgtt ttaaaaggtg
    19021 agaaaccaga aaatatagca gttgagttgc ctgaaaaact ggaattgcat actaatcaag
    19081 aaatggcaga tgcattggga attgatatta gtaagttaga aggcaaggaa taaggaggat
    19141 taagatgaat tttgtgttat ctagtttatc agaaggtttg ttgtggtcga ttgtggcgat
    19201 tggggtctac ttgactttcc gtattttgga tattgcggat atgactgctg agggagcctt
    19261 tcctctgggg gcagcagtcg ttgtatcaca gatacaggca ggggcaaatc cttggcttgc
    19321 gattttactt gctttgctgg caggtatggt agcaggtctt gtatcaggaa tgctccacac
    19381 caagatgaaa atcccagctc tcttgacagg gattgtgacc ttgacagggc tctattcaat
    19441 caatattaaa atcatgggca gtgtactcaa tctttccttg ggagattctg caaccgtctt
    19501 taaacagttg gcgagcttgg gtctgacaaa tgaaggagct gttttctcac ttagtttagt
    19561 ctgtctctta cttgtttggt cttgaccctt ttgatgaaaa cagagattgg tttggtcttg
    19621 cgttcgactg gggataatat cccgatgagt gaggccaatg gagtcaatgt agacaccatg
    19681 aagattgttg gttacatgat ttcaaacggt ttgattgccc tatgtggttc cttgtttgcc
    19741 caaaatgatg gattttcaga tgtgacttct gggacaggaa ccattgttgt tggtttgagt
    19801 tcggtgatta ttgcggaagt cttgatacac gacttgacca ttggaggccg cttattatcc
    19861 atcggaatcg gtgctattgt ttaccgtttg attattttaa atatctatga aattccaaat
    19921 ctagatcaaa acttggtacg tctctttaat gcaatcttgc tcgctttggt tttatttgca
    19981 ccagaattgc aaaagagatt aaagattcgt ggtctgaaat tgagaaatga ataggaggag
    20041 aaagttatgg caagtttgtt aacacttgaa aatattcaca agacatttga agcagggacg
    20101 gtcaatgaga accatgtcct caaaggatta gatttagagg ttgaagaggg agattttatc
    20161 tctgtgattg gtggaaatgg agcaggaaaa tccactttga tgaatatctt ggctggcaat
    20221 ctatcgatgg acgaagggga ccttctactg gcagggaaat ccattaaaaa tctgagtgtc
    20281 agaaagagag ccaaggatat tgcccgtgtt tttcaagctc ctaagatggg aacagcttct
    20341 cgtttgacga ttgaggagaa tatggctatt gccttgagac gtgggcaaaa gagagggctt
    20401 ggttggggcg tgaaggagaa ggatagaatc cagttccaag aggccttgaa ggagttgaat
    20461 attggtcttg aaaaccgctt aaaagtagat actcaatatc tctcaggagg acaaagacag
    20521 gctttgaccc tagtcatggc agctctggtg aaacccaaac ttttgctttt ggatgaacat
    20581 actgcggcac ttgacccgaa aaccagtcaa atggtgatgg acttgacgca aaagattgtg
    20641 gagcaccatc agttgacgac tttgatgatt acccatgata tgaatcatgc gattgagtac
    20701 ggcaatcgtc tcattatgct ctatcaaggc aagatagtgg tggatgtcaa gggagaagag
    20761 aaaaagcatc tgacagttga agaccttatg catctcttcc agaaaaatag tggccaaagt
    20821 ctggtcagtg atgaattagt tttgagataa agaaaaaggc tgagattggt gtctcagtct
    20881 tttatttctt gcgttttgca aaatctacaa atctaaattt ttctaactta tggcgacttt
    20941 cggtaaactg aaattggcgt ccgtcttgga gatagacttt tgatttaatc gaaacgacat
    21001 aagggtcttt gccaatgtcc atgagaatct tgtctcggtc gcttgagtgg tcaatggtga
    21061 tttccttctg agcataatca ataaggagtt tgaggccatt ttctatataa gaatagatag
    21121 actgctcagc aatttggcga gtgagatttg ggatgagttc catatccaga tagtctgtat
    21181 ccagaacgga taccagatca tccaccacac gctggcggac caccttccaa accatccgaa
    21241 actctgggaa accggttatc agtgaggatt ttttatcaat aataatcttg tccagactga
    21301 ccacgttggt tttagagcgc agtccaagtt ctttaactag ttcttggtag ctggttaggt
    21361 tggatacagg gaaattgacg gtttcttctt tgacgacttg agaaccttgc cctcttatct
    21421 ttttgatcaa tccttcctct tggaggagag acagggcctt tcggacggta tcacgactca
    21481 cttgatattg ctccataagg tcgtgctcgc taggaaggaa atctccgaca gcgtaagtct
    21541 cgttttgaat ggtttcttgg atttgcttaa ataattgttg gtatttcttc attttgcctg
    21601 cttaaatagg tttttagtct agtttaatga acacctgtat ctattttacc atacaagtgc
    21661 tagaaaattt acaaaaaaac acccttttta taccaaacaa gttgcagaca agtttggtat
    21721 cgtttacaat atacttatca aatcaaactt gctttgacaa gtataaggag aatcaaatgg
    21781 gaaaatttga acaagaagcc aaagatctgc ttcaggcaat tggaggcaaa gaaaatgtga
    21841 ctgccgtcac ccactgtgcg acacggatgc gctttgtttt aggagatgat aagaaggcta
    21901 atgttaaagc tatcgagtca attccagctg ttaaaggaac ttttacaaat gcaggtcaat
    21961 ttcaggtaat cattggaaat gacgtgccca tcttttataa tgattttaca gccgtttcag
    22021 gtattgaggg tgtttccaaa gaagcagcca agtctgcagc taagagtaat caaaacgtgg
    22081 tccaacgtgt tatgaccact ctggcggaga tttttactcc gattattcca gccttgatag
    22141 tcggaggatt gatcctcggt ttccgtaatg tcttggaagg tgtccattgg tcgatgttgg
    22201 atggcaagac catcacagaa tcctctcagt tttgggcagg tgtcaatcac ttcctctggt
    22261 tgcctggtga agctatcttc cagttcttac cagtagggat tacttggtct gtttctcgta
    22321 agatgggaac cagccaaatt ttgggaattg ttctcggaat ctgtttggta tcgcctcagt
    22381 tgctcaatgc ctatgcggtt gcttcaacgc cagcagctga tatcgcggca aactgggttt
    22441 ggaattttgg ctattttact gttaatcgta tcggttacca agcccaagtt atcccagcct
    22501 tgcttgcagg tttgagtctg tcttatcttg aaatcttctg gcgcaagcat atcccagaag
    22561 tcatttctat gatttttgta cctttcttgt cattgattcc agccttgatt ttggctcata
    22621 ctgttttggg accaatcggt tggacaattg gacaaggact ttcatcagtt gtcttggcag
    22681 gtttaactgg tccagttaaa tggctcttcg gtgcaatttt tggtgccctc tacgctccat
    22741 ttgtcatcac aggtctgcac catatgacca atgccattga tacacaattg attgcggatg
    22801 ctggtggcac tgccctatgg ccaatgattg ctctttctaa tattgctcaa ggctcagccg
    22861 tgtttgccta ttatttcatg catcgccatg atgagcgtga ggctcaggtt tcacttcctg
    22921 caaccatttc agcctatctc ggtgttacag aaccagctct ttttggggtt aacgtaaaat
    22981 atatttatcc atttgttgct gggatgactg gttcagccct tgcaggcatg ttatccgtta
    23041 cttttaatgt aactgcggct tctattggta tcggtggttt gccaggtatt ctctctattc
    23101 aacctcaata catgctgcca tttgcaggaa ctatgctagt tgcgattgtt gttccaatgc
    23161 tcttgacttt cttcttccgc aaggctggtc tctttacaaa aacagagggc gatacgaact
    23221 tgcaggcaga attcgttgct caagaagaag cagaatttgt gaaccatgaa ccagtagaac
    23281 ttacttcggt agaaattatc agcccactaa ctggccaagt gaaagaattg agtcaagcga
    23341 cggatcctat ttttgcatca ggtgtcatgg ggcaaggtct agtcattgaa ccaagccaag
    23401 gtgagttgac ctctccagtt aatgggacag tgacggttct tttccctacc aagcatgcca
    23461 tcggcattgt ctctgacgag ggagttgaat tgctcatcca catcggtatg gatacagtag
    23521 gtcttgatgg caaaggtttt gaaagtcttg tagtccaagg agatcacgtt acagttggtc
    23581 agcaactgat tcgttttgat atggatgtca ttaaggctgc aggtctggtg acagaaactc
    23641 ctgttatcat caccaaccaa gatgcttata cagcgactat tcccggaact tatccgacaa
    23701 cgatccaagc tggagcatct ctcatggtcg ctacacgaat ctaatactct tcgaaaatct
    23761 cttcaaacca cgtcagctct atctgcaacc tcaaaatagt gttttgagca acctgtggct
    23821 agcttcctag tttgttcttt gattttcatt gagtataatt gaaatagcac aaatagggac
    23881 ggaagactgc ttcctccctt ttatcagaaa aggagaaaca gatgacactt gataaaggaa
    23941 aagtagtcta tcaaatctat ccaaaatctt acaaagacac cactgaaaac ggtattgggg
    24001 atttccgtgg gattatcgaa aaaattccct atttagccaa actaggtgtg gatatggtct
    24061 ggctcaatcc attctatcca agccctcaac gggataatgg ttacgatatt tcagattata
    24121 tggcagtgga tcctcttttt ggtgatatgg ctgattttga ggaaatggtg tgtgtcggta
    24181 aagagcacaa gattgacttt atgctggaca tggtacttaa tcattgttcg acagagcatg
    24241 aatggtttca gaaagcccta gctggtgata agtattatca agactttttc ttcatccaag
    24301 accaaccaac agattggcag tctaagtttg gtggttctgc atgggcgcct ttcggggata
    24361 ctgggaaata ctatcttcac ctatttgatg agacccaggc tgaccttaac tggcgcaatt
    24421 ccaatgtccg taaggagctt ttcaaggttg ttaatttctg gcgcgacaag ggtgtcaaag
    24481 gtttccgatt tgatgtgatc aatttgatcg gtaaggacga ggtttcagtg gactgtcctg
    24541 aaaatgaagg gaagccagct tatacagaca aacccatcgt tcataactat ttgcgtatga
    24601 tgaaccaagc cacttttgga tctgacgata gctttatgac agttggggaa atgtcttcta
    24661 ccaccatgga aaactgtgtc ctctattcgt cgcctgatcg tcaggaatta tccatgacct
    24721 ttaattttca tcacctcaag gtggactata aggatggaca aaagtggacc ttggctccct
    24781 ttgattttga agagttgaag agtctttacc atagttgggg taaggaaatg agtgataaag
    24841 acggttggag tgccctcttt tggaacaatc acgatcaacc acgtgccttg aaccgttttg
    24901 tcgatattca aaacttccgc aaggaaggag ctaccatgct agcagccagc attcacctgt
    24961 cacgtgggac accttatatc tacatgggtg aggaaatcgg gatgattgac ccagactatg
    25021 attctatggc tgattatgtg gatgtcgaat cgcttaatgc ctatcagatg ctcttagaag
    25081 aaggaaagag tcagcaagaa gccttccaga ttattcaagc taagtcgcgt gataattcac
    25141 gtattcccat gcagtgggat acttctgaaa atgcaggatt ttcaacaggc actccatggt
    25201 tgaaagttgg taaatcctat aaagatatca atgtagaaaa tgaaatcaaa ggtctgattt
    25261 tcaccttcta tcaagacttg attcgactgc gtaaggaaat gccaatcatt tcagaaggaa
    25321 attacaaacc agcctttgaa gatagcaaac aagtctacgc ttttgaacgc cagtttgagg
    25381 atcaaaagtt actagtgctc aataactttt atgccaaaga agtggaaatc gacttgccag
    25441 cagtctacca aaatggacag attttgattt caaactatga agatgcagaa gtgtctgaga
    25501 aaattctact caaaccctat caaacactgg ctatttatgt aaattaatac tcttcgaaaa
    25561 tctcttcaaa ccgtgtcagt tttatctgta acctcaaagc ggtgctttga gcaacctgtg
    25621 gctagcttcc tagtttgctc tttgattttc attgagtata aacttagcaa ggagacctct
    25681 ttttcagaaa agcagggttc tttttgctgt ctattccatc cttgaaagtg tagaacaaac
    25741 tggtcagggt ggctagtttg tggtataatg aaagggactc aaaaagaaac aggagaaaaa
    25801 tgatggattt acttttagca attgtattga ttgtgctagc ttttctagga ggagctcttg
    25861 gaggaatgta cttggttcgt aagcaaatcg aaaaagaatt tgctgacaac ccacgtttga
    25921 atgctgaagc agttcgtact cttttgagtg caaatggtca aaaaccaagc gaagctaagg
    25981 tacaacaagt ttaccaccaa atcatccgcc aacaaaaggc agcccttgct aacaataaaa
    26041 agaaaaaata aataaggaaa agtctgggat gaaagttcca gacttctcac tatgttggtt
    26101 atggtttagg gatgagactt tttccttgca ttctattgat atttgattat gattaagaga
    26161 gaggtagttg acattctatc aagctgtcgg tcagttcgtt cagtacaagg aatcataatg
    26221 aacgatcaat cagaaaaaag actagaaaga agactgtatg gataatcgac caattggttt
    26281 tttggattcg ggtgtcgggg gcttgaccgt tgtgcgcgag ctcatgcgcc agcttcccca
    26341 tgaagaaatc gtctatattg gagattcggc gcgggcgccc tatggccccc gtcctgctga
    26401 gcaaattcgt gaatatactt ggcagctggt caactttctc ttgaccaagg atgtcaaaat
    26461 gattgtcatt gcttgtaaca ctgcgactgc ggtcgtctgg gaagaaatca aggctcaact
    26521 agatattcct gtcttgggtg taattttgcc aggagcttcg gcagccatca agtccagtca
    26581 aggtgggaaa atcggagtga ttggaacgcc catgacggta caatcagaca tataccgtca
    26641 gaaaatccat gatctggatc ccgacttaca ggtggagagc ttggcctgtc ccaagtttgc
    26701 tcccttggtt gagtcaggtg ccctgtcaac cagtgttacc aagaaggtgg tctatgaaac
    26761 cctgcgtccc ttggttggaa aggtggatag cctgattttg ggctgtactc attatccact
    26821 ccttcgccct attatccaaa atgtgatggg gccaaaggtt cagctcatcg atagtggggc
    26881 agagtgcgta cgggatatct cagtcttact caattatttt gaaatcaatc gtggtcgcga
    26941 tgctggacca ctccatcacc gtttttacac aacagccagt agccaaagtt ttgcacaaat
    27001 tggtgaagaa tggctggaaa aagagattca tgtggagcat gtagaattat gacaaataaa
    27061 atttatgaat ataaggatga ccaggactgg tatgttgggt cttatagtat ttttggtggc
    27121 gttaacagtt tgagcgacta taagacagat tttcctctgt ttgaattctc caaaatattt
    27181 ggagatgaag agtatggttt cccgctttca gttactgttt tacgctatgg ttctacctac
    27241 cgtttgttct cctttgtggt agacatgctt aatcaagaaa tgggacgaaa cttggaagtt
    27301 attcaacgtc atggggccct gctcttggtt gaaaatgggc aactcttgta tgtagaattg
    27361 cctaaagaag gggtcaatgt tcatgatttc tttgagacaa gcaaggtcag agaaaccttg
    27421 ttgattgcga ctcgtaacga aggtaaaacc aaggaattcc gagctatctt tgataagtta
    27481 ggctacgatg tggaaaatct taatgactac cctgacctgc ctgaagtagc agaaacaggt
    27541 atgacctttg aagaaaatgc ccgccttaag gcagaaacca tttctcaatt aacgggcaag
    27601 atggttttgg cagatgattc tggtctcaaa gtcgatgtcc ttggtggctt accaggcgtc
    27661 tggtcagctc gtttcgcagg tgtgggagca actgaccgtg aaaataatgc caaactcttg
    27721 cacgaattgg ccatggtctt tgaactcaag gaccgctcgg ctcagttcca cacaacccta
    27781 gtcgtagcca gcccaaataa ggaaagttta gttgttgaag cagactggtc aggttatatt
    27841 aactttgaac ctaagggtga aaatggcttt ggctatgatc ccctcttcct tgtaggagag
    27901 acaggtgagt catcagctga attaaccctg gaagaaaaaa atagtcaatc tcaccgtgcc
    27961 ttagccgtta agaaactttt ggaggtattt ccatcatggc aaagcaaacc atcattgtaa
    28021 tgagcgattc ccatggcgat agcttgattg tggaagaagt ccgtgatcgc tatgtgggca
    28081 aagtcgatgc cgtttttcat aacggcgatt ctgaactacg tccggattct ccactttggg
    28141 agggcatccg cgttgttaaa gggaacatgg acttctacgc cggctaccca gaacgtctgg
    28201 tgactgagct tggttcgacc aagattatcc aaactcatgg tcacttgttt gacatcaatt
    28261 tcaactttca aaagttggac tactgggctc aggaggaaga ggccgctatc tgcctctatg
    28321 gtcacttgca tgtgccaagt gcttggatgg aaggcaagat cctctttcta aatccaggtt
    28381 ctatcagcca accacgaggt accatcagag aatgtctcta tgctcgtgtg gagattgatg
    28441 atagttactt caaagtggac tttttgacac gagatcacga ggtgtatcca ggtttgtcca
    28501 aggagtttag ccgatgattg ccaaggagtt tgagactttc ttgttggggc aggaggaaac
    28561 ttttttgacc cctgctaaaa atctagctgt gttgattgat acccacaatg cggatcatgc
    28621 gaccctcttg ctcagtcaga tgacctatac ccgtgttccc gttgtgacag atgaaaaaca
    28681 gtttgttggg acgattggac tcagagatat tatggcttat cagatggagc atgacttgag
    28741 ccaagaaatc atggcggata cggatatcgt tcatatgaca aaaacggacg tagcggttgt
    28801 ttcgcctgat ttcaccatta cggaggtctt gcacaagcta gtagatgagt ccttcttacc
    28861 ggttgtggat gcagagggta ttttccaagg gattattacg cgcaagtcca tcctcaaggc
    28921 cgttaatgcc ctcttgcatg actttagtaa ggaatatgag attcgatgcc aatgagagac
    28981 aggatttcag cctttttaga ggaaaagcag ggcttgtctg tcaattccaa gcagtcctat
    29041 aagtatgatt tggagcaatt tttagacatg gtaggtgagc ggatttctga gaccagtctc
    29101 aagatttacc aagcccagct agccaatcta aaaatcagcg cccagaagcg aaagatttcg
    29161 gcctgtaacc aatttctata ctttctctat caaaaaggag aggtggacag cttttaccgc
    29221 ttggaattag ccaaacaagc tgaaaagaag acggaaaagc cagagattct atacctagac
    29281 tctttttggc aggaaagcga ccatccagag ggccgcttgc tagcgctctt aatcctagaa
    29341 atggggctct tgcccagtga gattttagcc atcaaggttg cggacatcaa tctggatttt
    29401 caggtgttgc gaatcagcaa ggcttcccaa cagaggattg tcaccattcc cacggccttg
    29461 ctttcagaat tggaaccctt gatggggcag acctatcttt ttgaaagagg agagaaaccc
    29521 tattctcgtc agtgggcctt tcgtcagtta gaatcttttg tcaaggagaa aggttttcca
    29581 tccttatcag ctcaagtctt acgtgaacag tttattctaa gacaaataga aaacaaggtc
    29641 gatttgtacg aaattgcaaa aaaattagga ttaaaaacag tcctgacctt agaaaaatat
    29701 agataatgga tattaaatta aaagattttg aaggacccct ggacttgctc ttgcatctgg
    29761 tttctaagta ccagatggat atctacgatg tgcccattac ggaagtcatc gaacagtatc
    29821 tagcctatgt ctcaaccctg caggccatgc gtctggaagt gacgggtgag tacatggtca
    29881 tggctagtca gctcatgctg attaagagtc gtaaactcct tccgaaggta gcagaagtga
    29941 cagacttggg ggatgacctg gagcaggacc tcctctctca aatcgaagaa tatcgcaagt
    30001 tcaagctctt gggtgagcac ttggaagcca agcaccaaga acgggcccag tattattcca
    30061 aagcgccgac agagttgatt tacgaagatg cggagcttgt gcatgacaag acgaccattg
    30121 acctcttttt ggctttttca aatatcctag ccaagaaaaa agaggagttt gcacaaaatc
    30181 acacgacgat cttgcgggat gagtataaga ttgaggacat gatgattatc gtgaaagagt
    30241 ccttgattgg acgagatcaa ttgcgcttgc aggatttgtt caaggaagcc cagaatgtcc
    30301 aagaggtcat caccctcttt ttggcaaccc tagagttaat caaaacccag gagctgatcc
    30361 tcgtgcaaga ggagagtttt ggagatatct atctcatgga aaagaaggaa gaaagtcaag
    30421 tgcctcaaag ctagacttga tagagaggaa agatgagtac tttagcaaaa atagaagcgc
    30481 tcttgtttgt agcgggtgaa gatgggattc gggtccgcca gttagctgaa ctcctctctc
    30541 tgccaccgac aggcatccag caaagtttag gaaaattagc ccagaagtat gaaaaggacc
    30601 cagattccag tttggctttg attgagacaa gtggtgctta tagattggtg accaagcctc
    30661 aatttgcaga gattttgaag gaatactcta aggcgcctat caaccagagc ttgtctcggg
    30721 ctgcccttga gaccttgtcc attattgcct acaaacagcc gattacgcgg atagaaattg
    30781 atgccatccg tggagttaac tcgagtggag ccttggcaaa gttgcaggct tttgacctga
    30841 taaaggaaga cgggaaaaag gaagtattgg ggcgccccaa cctctatgtg actacagatt
    30901 atttcctaga ttacatgggg ataaaccatt tagaagaatt accagtgatt gatgagcttg
    30961 agattcaagc ccaagaaagc caattatttg gtgaaaggat agaagaagat gagaatcaat
    31021 aagtatattg cccacgcagg tgtggccagt aggagaaaag cagaagagct gattaagcaa
    31081 ggcttggtga cggttaacgg tcaagtggtg cgtgaactag caaccactat caagtcaggc
    31141 gacaaggtcg aagttgaagg tcaacctatc tacaacgaag aaaaggtcta ctatctgctt
    31201 aacaaaccac gcggtgtcat ttccagtgtg acagatgata agggtcgcaa gacggttgtc
    31261 gacctcttgc ccaatgtcaa agagcgtatt taccctgtgg gtcgtttgga ctgggataca
    31321 tcaggagtct tgattttgac caatgatggg gactttacag acgagatgat tcaccctcgt
    31381 aatgagattg acaaggttta tgtcgcgcgt gttaaaggtg tggccaataa ggacaatctt
    31441 cgccccttga cccgtggtct tgagattgat ggtaagaaaa ccaagccagc tgtttatgaa
    31501 attctcaaag tggacccagt caaaaatcgc tctgtggtgc agttgaccat ccatgaaggg
    31561 cgtaaccatc aggttaaaaa gatgtttgaa gctgttggtc tccaagtaga taagttgtct
    31621 cggactcgtt tcggacacct agacttgaca ggactccgtc caggagaatc ccgtcgtctt
    31681 aataaaaaag aaatcagcca actacacacc atggctgtaa ctaagaaata atgaaacgaa
    31741 ttttaatagc gcttgtgcgc ttttaccaac gttttatctc accagtcttt ccaccctctt
    31801 gtcgctttga gctgacttgt tccaactaca tgattcaggc tattgaaaaa catggtttta
    31861 agggggtatt gatgggcttg gctcggattt tacgttgtca tccctggtcg aaaacaggta
    31921 aggaccccat tccagaccac ttttccctta aacgaaatca agaaggggaa tgaggtgggg
    31981 taaatagatt tcaaaatgat aaaaacgcat cctatcaggt ttgagtaaac ttgataggat
    32041 gcgttttaga atgtcaaaat tttatactct tcgaaaatct cttcaaaccg cgtcagcttt
    32101 catctgcaac ctcaaaacag tgttttgagc aacctgcggc tagtttccta gtttgctctt
    32161 tgattttcat tgagtattaa attgagtttg aagtggctta tttcaaagct ttttgtatgt
    32221 cttcaatcat gagttttgtt gattcaagtc cgcctccgct tagataccag aggtctggtg
    32281 ttagttggat aatcttacca tttttagcag caggtgtttc agcgataagg gcattttcta
    32341 ggacaccgtc gttgctagag ttgtccccac cgatggcaag ggtacggttg atgacaaaga
    32401 ggatgtcagg gttgatttct ttgacacttt caaagctgac ttcttgtccg tggcgtgagt
    32461 cttcaaattt tgtatcagtt ggtttgaatt tcaaggtttg gtacaagaaa gagaaacgag
    32521 atttggcacc aaaggctgcc atttttcctt cattaaggag gatcgcaagg gcttttttgt
    32581 cagagctttc atttttagta gcgacttctt ggatgctctt gtctagcttg gccaattctt
    32641 ccttggcttt ttgtgtacta gtttcgccga aggcacttgc taaggattcg atattagcct
    32701 tggtagaagt ccagtagtca tccttgcttg cttggaagag aacggttggg gcgatttctt
    32761 tgaatttgtc tacgaatttt tgtgtacgtg gtgaagcgat aatcaaatca ggctcaaggg
    32821 cggcgatagc ttctaaatca ggttctttca tagaaccaac atttttgaca gttcccacta
    32881 ggtcttttag ataagtcgga acagtttttg taggcattcc gacgatattt ttttcaaatc
    32941 ctaaagcgcg aatagtatcc gcagcgccga ggtcaaaggt cacaatcttt tcaggaactt
    33001 tggaaagttt gacctcgtcc agtgaacttt taatggttat ctctgttgga gcagagctac
    33061 tggtctctgt ctgactagtg cttgagtttg tactacatgc accaagtagg agcaagaagc
    33121 tggccactag ggcagtgaaa taaagtttaa gggatgtttt cataatttct cctttttaaa
    33181 atgtgataac gatttaggga gtctcttaat cttattgact aagagactga aggttctcta
    33241 acttgagctt ttatgttact agctatagat acagatcttt ttgttattga tatcagctag
    33301 cgtgatggga atctcataaa gttgactgag caggtcagcc tgcatgattt gatcggttct
    33361 tcccttgcta aagacctggc cgtccttgaa ggcgacaatt tcatctgcat actgactggc
    33421 catgttgata tcgtggagga cgatgataat ggtcttgccg agttcctcca ccagtcgtcg
    33481 aagaatctgc atcatgctga cgctttgctt gatatcgaga ttgttgagtg gttcgtccag
    33541 caagataaag tccgtatcct gggccagtac catagcgata aagacgcgct ggagttgccc
    33601 ccctgacagg ctattgatgt agcggtcttt taagttggtc agttccaaat agttcagagt
    33661 ttctcggatt ttttcccagt cttctgatct aagtcgacct cggctgtagg gaaaacgtcc
    33721 aaaactgacc agttcttcaa cagtcaattt ggcttggtaa ttgattttct gttttaggat
    33781 ggttagttct tgagccagtt cttgcgaatt ccagctctcg atttcacgtc ctttgatact
    33841 gagaactccc tgatctttct tggttagtct gctcatgatg gagaggagag tcgattttcc
    33901 agcaccattt ggaccaataa aggctgtcag tttttgagga ctgacttcaa gcgaaatgcc
    33961 ttgcaaaata tcctgttttt gaatggattt gtcaatgttt tccagtttca ctgacgagcc
    34021 ctcctatata gtaagataaa gaataagaag ccacccacac tctcaatgat catactgata
    34081 cgaatttcca gtgcaaagac tcgttcaatt aaggcttgcc ccaaggttaa gctaataaat
    34141 ccaaccagaa tggccactat aaagagtaac ttgtgctgat agtctttgac aatcaggtag
    34201 gtgaggttgg ccagcataaa gctgaagaag gccataggtc ctaccaaggc agtggccgtt
    34261 gaggtcaaaa gcacgattcc ccagagtaac tctttctgtt ctttttcaac atcgagtccc
    34321 aatatctgag ccgtttctct ttgcaggtgc aagacatcta gaacgactgc ttttcgaaag
    34381 aaaaagattg tcaaagcgag gatgatcaga gaaccgatgg ctaggatgga agtgttgaga
    34441 tgttgaaagg aggcaaaaag actattttgc agtttatcgt attcgtttgg atccattagg
    34501 acttgaagga aggtgctgat atttcgaaag agacttctga gcgctagaca gatcagcagg
    34561 acgaagacca ggtcttgctt catcagtgtc ttcaagtaac cttgtaaggc gagaaagaag
    34621 agggactgga caagaagtaa gactaggaat tctaagatag gggatttgcc aagttgaaga
    34681 aacttgcttt caaaaaccag tagtagggtt tgtagtagga cgtagaagga ttcaattccc
    34741 aaaatactag gcgtcaggaa gcgattttcc gtcagggttt gaaaactaat ggtcgaaatc
    34801 ccagtcgcga tggctaccaa gagataaacg atgatctttt gggaacgcaa cttccaagca
    34861 aaggctgaca agtgagtgat gggccaaaag tagagaagac aagctccgat ggcaagaata
    34921 atgagaatcc agaagagctt ggtatgtttg cttttagtct gcatcttttc gtccccctct
    34981 ccagagaagt aggataaaga cgagactacc gatgattcct agcaagagac tgacagacaa
    35041 ctcatagggc ctaatcagaa ctcgggatag gatatcgcaa gccagaacta gattggcacc
    35101 aaccagtgcg accatgagtt tggtttgact tagattatct ccatagcgct tgcgaacaag
    35161 attgggaacg ataactccga gaaatggtag gtcacccacg gtaatcatgg tgacgcttgt
    35221 cgttagcgcc accagaaaga gggccagttt ttcaagtagg gagtaggaaa tccccaaact
    35281 ctcgctggtt tctttcccta gattcatgat ggtgaaggtt tgggataatt tccaaacggt
    35341 tatcaggatg atgaggccta agaagagcca ctcatactga tgggtctgaa tcatggagaa
    35401 ggagccctgg gtccaggcag tcatactctg aaccagattg aaacgatagg cgataacttc
    35461 tgtgactgag ccgataatcc cgctatagat gatcccaatc agaggcaaca tccacctttc
    35521 ctttacagta aaaatggtca taaaggctag gaagaagagg gtgaatacga tggatgaaac
    35581 aaaagcgaag agcatctttt gggtcagact agccgatgga aagacaaaaa ggctcagcac
    35641 cattcccagt ttggcggctt cagtcgttcc aactgtactc ggtgcagcaa actgattttg
    35701 ggtaatagtc tgcatgagaa ggcctgccat actcatacta gaggcagtca ggagaatact
    35761 gatagttctt gggagacggg actcttgaaa gaggagccag gtctgctggt cgaaatcaaa
    35821 tagctttccc catgaaaaat cactggtccc aatgctaata gagagaaaga ctaggagtag
    35881 aagtaagcca attaaataat gagaaagttt cataccccgt cctttcatgt agatttggta
    35941 tcgaaagata tctgcggata taaatgtaac attatttttc taatctgtca ataaaatttc
    36001 tgacaattta ataaatacaa caaggagaga gcaacaagac tttctccttt gttatcctat
    36061 tctaaaatgt ttttacctta atctgataaa ataatatctt cgagggagta gctagccgtc
    36121 caatcaagat attgtttagc ttttgaagca tctgctagga cactggctgg gtcactagca
    36181 cgtcgagcaa caatctcgtg tgggattttt taatttagta attcttcagc agttttaaag
    36241 atttctttga tagtatagcc ttttttagtt cctaagttaa agatttgaga agaactgtct
    36301 tcttgaaata ggtagttcat tcctttaaca tgagcctatg caaggtccaa gacataaatg
    36361 taatctcgaa tacatgaacc gtcacgtgta tcgtagtcat ctccaaatat ttttaagcta
    36421 tcatgttgtc ccaatgcggt cttgttgata tttggaatga tgtgagttgg atttttcaca
    36481 cgcagaccgt ttgaagcatc catttcagcc ccagcaacat taaagtaacg gaaaataaca
    36541 tatttccagt cgtagcgatt ggccatccag taaatcattc gttcgcccat cagttttgtc
    36601 tctgcataag ggttgacagg gtcgagcagg gtatcttcag tcaccggctt gtcaatacag
    36661 ttatttccac agagagaagc agtcgaagag aacatgattt tttgaatgcc aacttcagat
    36721 aagactttga gaacttggtt cataccagca acgttggtag tgaagtattt acttggattt
    36781 tcaatacttt cgctcacaac aatttcacct gcacaatgga ggacagcatc aatctgattt
    36841 tcttctaagt aagcctttaa ggcgctagca tcataaacat ccagttcttt aaagctagca
    36901 tgactatcca cagccgctcg atttcctgtg gagagattat cgaggacatg cacctgatag
    36961 ccagcattta aaagagcttt aacggtatgg gagccaatgt agctagtccc acctgtaaca
    37021 agaattgttt tggtcatgat tttttccttt tctagttttg tactatagta aattgaaata
    37081 agatatgaac aactctatta ggaaagtcaa attaatttct agaaatgttt cagcagctac
    37141 agcgtactat tccaaactca accaactata tatttaaaga aagaagaaag ggaagtcaac
    37201 tattttctgt aaatttcatg aaaaatccaa acaactttga tggtgtattg tttttttgtt
    37261 tggaaataaa tattcgagtt aattttggaa tgtttactag attttgcact acatgcaaga
    37321 gaatactatc cttttctaag atagagcagg actaagatac taacttagaa atccaccttc
    37381 ccactatcct tctcctataa aaagtggtaa aatggatgaa agaaagaagg aactgaaatg
    37441 acaacattat tttcaaaaat taaagaagta acagaacttg ctgcagtctc aggtcatgaa
    37501 gcgcctgtcc gtgcttatct tcgtgaaaag ttgacaccgc atgtggatga agtggtgaca
    37561 gatggcttgg gtggtatttt tggtatcaaa cattcagaag ctgtggatgc accgcgcgtc
    37621 ttggtcgctt ctcatatgga cgaagttggt tttatggtca gcgaaatcaa gccagatggt
    37681 accttccgtg tcgtagaaat cggtggctgg aaccccatgg tggttagcag ccaacgtttc
    37741 aaactcttga ctcgtgatgg tcatgaaatt cctgtgattt caggttctgt tcctccgcat
    37801 ttgactcgtg gaaagggggg accaaccatg ccagccattg ccgatatcgt ttttgatggt
    37861 ggttttgcgg acaaggctga ggcagaaagt tttggcatcc gtcctggtga taccatcgta
    37921 ccagatagtt ctgcaatttt gacagccaat gaaaaaaata tcatctcaaa agcttgggat
    37981 aaccgctacg gtgtcctcat ggtaagcgag ctagctgaag ctttatcagg tcaaaaactc
    38041 ggcaatgaac tctatctggg ttctaacgtc caagaagaag ttggtctgcg tggcgctcat
    38101 acctctacaa ccaagtttga cccagaagtc ttcctcgcag ttgattgctc accagcaggt
    38161 gatgtctacg gtggtcaagg caagattgga gatggaacct tgattcgttt ctatgatcca
    38221 ggtcacttgc ttctcccagg gatgaaggat ttccttttga caacggctga agaagctggt
    38281 atcaagtacc aatactactg tggtaaaggc ggaacagatg caggtgcagc tcatctgaaa
    38341 aatggtggtg tcccatcaac aactatcggt gtctgcgctc gttatatcca ttctcaccaa
    38401 accctctatg caatggatga cttcctagaa gcgcaagctt tcttacaagc cttggtgaag
    38461 aaattggatc gttcaacggt tgatttgatt aaacattatt aaaccataag ggaggtggta
    38521 gggatggcag aaccaaacct agaaagcctt ataaaagatc tttacaatca tgctcgacat
    38581 gatttgagtg aagatttagt tgctgctctc ctagagacta ctaaaaaact acctactaca
    38641 aatgagcaat tgcaggcagt tcgtctctca ggcctggtca atcgtgaatt gctcctaaat
    38701 cccaaacatc cagcacctga gttgctcaac ttggctcgct ttatcaaaag agaagaagcc
    38761 aagtacagag gaactgcgac ttctgcgctt atgtatgagg aactctttaa aatgctttga
    38821 ttccattgtg gatcaaagca ttttttgtaa gatctatctc gtgagcgttc aaatagtagt
    38881 aacaaggaat catgagaagt cagccgagcc catagtagtg aagaaacttc tgtaatggaa
    38941 gtggagcgaa gtgaggaatc gtcaaacggt aggggatagg ctgtttgaag ggtgctacga
    39001 aaaagatagg gtaaggtgaa attatagcgg aatgaaataa gatatgaaca aattgattga
    39061 ggaaattaaa tgaatttata gaaatctttt agcagtcatg gtgtcctatt ccagtttcga
    39121 aatgctataa atacgaacaa attgattggg aaattcaaat cgctttctat caatgtttta
    39181 gaagatacag tgctctagtc taacttcaat atactataaa agaacagatg gaagcaatta
    39241 tgatttactt ctatctttaa aataaatggt ctgataggaa aaatgtgtcc cctcataaaa
    39301 tataggatag tacgaatgga aggcttttgt agactggagg acgaaggagt ttagaaactc
    39361 tcgttaaaag ttagttgagc cggagtatgg tggtgtggat aattatcaaa aattatttct
    39421 aaatcgaaat agttgacagt tagaacgatg agtgttacaa ttgttttatt catttcgata
    39481 tcgaaataaa ttggaggtgt tatgaaagat ggtcatttgc tagcccatca tattcgtttg
    39541 ttgaatgggc ggatttttca aaagttactg agtcaagatc ctgaggctct ttataggggt
    39601 gaacagggca agattttagc ggttttatgg aatagtgaaa ctggctgcgc aactgcgaca
    39661 gatatcgcgc ttgcgactgg acttgcgaat aatacgctga cgactatgat aaaaaagcta
    39721 gaggaacaaa agcttgtaat tgttagtccg tgtggaaaag acaagcgtaa gaagtattta
    39781 gttttaacgg agttaggcaa gtcccagaaa gaagtggggc atcgtgtcag tcagaaattg
    39841 gatactatct tttacaaagg attttcagag gaagaaattc accaatttga aggttttcaa
    39901 gaaagaattt tggcgaatct gaaagagaag ggaaatgagg tttagaatat gtcacaacaa
    39961 gtgaaaaatg ctcacaacct atacatccat gccattcaag acggacgagt tgctgaggct
    40021 caagcccagt ctgtagggga tacctatatc caacattcga caggtgttcc tgacgggaaa
    40081 gaaggatttg cagccttctt tgcagatttc tttgagcgtc atccagagcg tcagattaag
    40141 attgtccgca ccattgagga tggcaatctg gtctttgttc atgttcatca atatctgaat
    40201 ggtggagaag ctcaatgggt gacgacggat actttccgtg cggatgagaa tggtcgtatt
    40261 gttgagcatt gggatgtcat tgactactat cgaacacctg aaaatgacca actagatcaa
    40321 atttttggag attttgaaat caaggatttg gacaagaaag cagaaaataa aaagctggtt
    40381 cgccgtttct tgacagaaat tttccaaaat ggggagctag agcagtggag tgattatgtg
    40441 gcagacgatt tgattcagca taatcatgat attggacaag gaagtgctgc ttataaaaac
    40501 tatgtggctg aatatagtgt cacttttgac tttgttttcc aactcttagg acaaggaaac
    40561 tatgtggtta gctatggtca gactcagatt gatggcgttg cttatgccca gtacgatatc
    40621 ttccgtttag agaacgggaa aattgtggag cattgggata ataaggaagt catgcctaag
    40681 gtagaagact tgaccaatcg agggaagttt taaattgagg acaaagaatg attgaataca
    40741 aaaatgtagc actgcgctac acagaaaagg atgtcttgag agatgtcaac ttacagattg
    40801 aggatgggga atttatggtt ttagtagggc cttctgggtc aggtaagacg accatgctca
    40861 agatgattaa ccgtcttttg gaaccaactg atggaaatat ttatatggat gggaagcgca
    40921 tcaaagacta tgatgagcgt gaacttcgtc tttctactgg ttatgtttta caggctattg
    40981 ctctttttcc aaatctaaca gttgcggaaa atattgctct cattcctgaa atgaaggggt
    41041 ggagcaagga agaaattacg aagaaaacag aagagctttt ggctaaggtt ggtttaccag
    41101 tagccgagta tgggcatcgc ttacctagtg aattatctgg tggagaacag caacgggtcg
    41161 gtattgtccg agctatgatt ggtcagccca agattttcct catggatgaa cccttttcgg
    41221 ccttggatgc tatttcgaga aaacagttgc aggttctgac aaaagaattg cataaagagt
    41281 ttgggatgac aacgattttt gtaacccatg atacggatga agccttgaag ttggcggacc
    41341 gtattgctgt cttgcaggat ggagaaattc gccaggtagc gaatcccgag acaattttaa
    41401 aagcgcctgc aacagacttt gtagcagact tgtttggagg tagtgttcat gactaattta
    41461 attgcaactt ttcaggatcg ttttagtgat tggttgacag ctctatctca acatttgcag
    41521 ttgtcacttt tgaccttgtt actagctatt ttgcttgcga ttcccttggc tgtttttctt
    41581 cgctatcatg agaagctggc cgactgggtc ttgcagattg caggtatttt ccagaccatc
    41641 ccgtctctgg ccttgttggg actctttatt cccttgatgg gaattgggac tttaccggca
    41701 ttgacagctc tagtgattta tgcgattttt ccgattttac aaaatactat tactgggctg
    41761 aagggaattg atccgagtct tcaagaggct gggattgcct ttgggatgac cagatgggag
    41821 cgtctcaaga agtttgaaat tccacttgcc atgcctgtta tcatgtctgg aattcggacg
    41881 gcagcggtct tgattatcgg tacggctacc ttggcgacct tgattggggc agggggactg
    41941 ggttccttta tcctgttggg aattgaccgt aataatgcca gtttgatttt gattggggcc
    42001 ctttcttctg cagtgctagc tattgccttt aacttcctac taaaagtaat ggaaaaagcg
    42061 aaattgcgga cgattttctc tggttttgcc ttggtggctt tattactggg tctgtcttat
    42121 agtccagccc ttttggctca aaaagagaag gaaaacgtga ttattgctgg gaaaataggc
    42181 ccagaaccag aaattttggc taatatgtat aaattgctga ttgaagaaaa taccagcatg
    42241 actgcgactg ttaaaccgaa ttttgggacg acaagtttcc tttatgaagc tctgaaaaaa
    42301 ggtgatattg acatttatcc tgaatttacc ggtacggtga ctgaaagttt gcttcaacca
    42361 tcacccaagg tgagtcatga gccagagcag gtttatcaag tggcgcgtga tggcattgcc
    42421 aagcaggatc atctagccta tctcaaacct atgtcttatc aaaataccta tgctgtagct
    42481 gttccgaaaa agattgctca agaatatggc ttgaagacca tttcggattt gaaaaaagtg
    42541 gaagggcagc tgaaggcagg ctttacgctt gagtttaacg accgtgaaga tggaaataag
    42601 ggcttgcaat caatgtatgg tctcaatctc aatgtggcga ctatgcagcc agctcttcgt
    42661 tatcaggcaa ttcagtcagg ggatattcaa atcacggatg cctattcgac tgatgcggaa
    42721 ttggagcgtt atgatttaca ggtcttggaa gatgacaagc aactcttccc accttatcaa
    42781 ggggctccac tcatgaaaga agctcttctc aagaaacacc cagagttgga aagagttctt
    42841 aatacattgg ctggtaagat tacagaaagc cagatgagcc agctcaacta ccaagtcggt
    42901 gttgaaggca agtcagcaaa gcaagtagcc aaggagtttc tccaagaaca aggtttgttg
    42961 aagaaatgat gggacagaga ctttaaacat actgaactca acttccttaa acgactagat
    43021 aaaagaatgc tcagacaatt tcgtctgggc ttt
//
LOCUS       DBEJNA010000016        42637 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEJNA010000016 DBEJNA010000000
VERSION     DBEJNA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.16"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(401..2128)
                     /gene="ezrA"
                     /locus_tag="ACL3JB_000967"
     CDS             complement(401..2128)
                     /gene="ezrA"
                     /locus_tag="ACL3JB_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0685722.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2210..4156)
                     /gene="gyrB"
                     /locus_tag="ACL3JB_000968"
     CDS             complement(2210..4156)
                     /gene="gyrB"
                     /locus_tag="ACL3JB_000968"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0685723.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4171..4734)
                     /locus_tag="ACL3JB_000969"
     CDS             complement(4171..4734)
                     /locus_tag="ACL3JB_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0685724.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQT
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4819..5373)
                     /locus_tag="ACL3JB_000970"
     CDS             complement(4819..5373)
                     /locus_tag="ACL3JB_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0685725.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5384..6607)
                     /locus_tag="ACL3JB_000971"
     CDS             complement(5384..6607)
                     /locus_tag="ACL3JB_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0685726.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6644..9094)
                     /locus_tag="ACL3JB_000972"
     CDS             complement(6644..9094)
                     /locus_tag="ACL3JB_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0685727.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDVHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATIK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9294..10223)
                     /locus_tag="ACL3JB_000973"
     CDS             complement(9294..10223)
                     /locus_tag="ACL3JB_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0685728.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNWIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10363..10650
                     /locus_tag="ACL3JB_000974"
     CDS             10363..10650
                     /locus_tag="ACL3JB_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0685729.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10684..12018)
                     /gene="ciaH"
                     /locus_tag="ACL3JB_000975"
     CDS             complement(10684..12018)
                     /gene="ciaH"
                     /locus_tag="ACL3JB_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0685730.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12008..12682)
                     /gene="ciaR"
                     /locus_tag="ACL3JB_000976"
     CDS             complement(12008..12682)
                     /gene="ciaR"
                     /locus_tag="ACL3JB_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0685731.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12791..15337)
                     /locus_tag="ACL3JB_000977"
     CDS             complement(12791..15337)
                     /locus_tag="ACL3JB_000977"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0685732.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15460..15900)
                     /locus_tag="ACL3JB_000978"
     CDS             complement(15460..15900)
                     /locus_tag="ACL3JB_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0685733.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15875..16744)
                     /locus_tag="ACL3JB_000979"
     CDS             complement(15875..16744)
                     /locus_tag="ACL3JB_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0685734.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16786..17514)
                     /locus_tag="ACL3JB_000980"
     CDS             complement(16786..17514)
                     /locus_tag="ACL3JB_000980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685735.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGLAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17522..18001)
                     /locus_tag="ACL3JB_000981"
     CDS             complement(17522..18001)
                     /locus_tag="ACL3JB_000981"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0685736.1"
                     /translation="MEIKKHFGVYAVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18012..18710)
                     /locus_tag="ACL3JB_000982"
     CDS             complement(18012..18710)
                     /locus_tag="ACL3JB_000982"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0685737.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18703..18939)
                     /locus_tag="ACL3JB_000983"
     CDS             complement(18703..18939)
                     /locus_tag="ACL3JB_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0685738.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19035..19961)
                     /locus_tag="ACL3JB_000984"
     CDS             complement(19035..19961)
                     /locus_tag="ACL3JB_000984"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0685739.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEEFVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSVAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20036..20851)
                     /locus_tag="ACL3JB_000985"
     CDS             complement(20036..20851)
                     /locus_tag="ACL3JB_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685740.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKFGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPDPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFHGFKKIKWSEV"
     gene            complement(20855..21175)
                     /locus_tag="ACL3JB_000986"
     CDS             complement(20855..21175)
                     /locus_tag="ACL3JB_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0685741.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21265..21501)
                     /locus_tag="ACL3JB_000987"
     CDS             complement(21265..21501)
                     /locus_tag="ACL3JB_000987"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685742.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     SKHVFEVVDETDEVSNHTYGRATLTWFEEIFEEY"
     gene            complement(21551..23548)
                     /gene="metG"
                     /locus_tag="ACL3JB_000988"
     CDS             complement(21551..23548)
                     /gene="metG"
                     /locus_tag="ACL3JB_000988"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0685743.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23672..24931)
                     /locus_tag="ACL3JB_000989"
     CDS             complement(23672..24931)
                     /locus_tag="ACL3JB_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685744.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24933..25634)
                     /locus_tag="ACL3JB_000990"
     CDS             complement(24933..25634)
                     /locus_tag="ACL3JB_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685745.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25618..26817)
                     /locus_tag="ACL3JB_000991"
     CDS             complement(25618..26817)
                     /locus_tag="ACL3JB_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0685746.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27103..28449
                     /gene="gor"
                     /locus_tag="ACL3JB_000992"
     CDS             27103..28449
                     /gene="gor"
                     /locus_tag="ACL3JB_000992"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0685747.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSSCTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28646..29182
                     /locus_tag="ACL3JB_000993"
     CDS             28646..29182
                     /locus_tag="ACL3JB_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0685748.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29243..29389
                     /locus_tag="ACL3JB_000994"
     CDS             29243..29389
                     /locus_tag="ACL3JB_000994"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685749.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(29386..29601)
                     /locus_tag="ACL3JB_000995"
     CDS             complement(29386..29601)
                     /locus_tag="ACL3JB_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0685750.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGASAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29699..30019
                     /locus_tag="ACL3JB_000996"
     CDS             29699..30019
                     /locus_tag="ACL3JB_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685751.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30050..30388)
                     /locus_tag="ACL3JB_000997"
     CDS             complement(30050..30388)
                     /locus_tag="ACL3JB_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0685752.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30400..31119)
                     /gene="trmD"
                     /locus_tag="ACL3JB_000998"
     CDS             complement(30400..31119)
                     /gene="trmD"
                     /locus_tag="ACL3JB_000998"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0685753.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31109..31627)
                     /gene="rimM"
                     /locus_tag="ACL3JB_000999"
     CDS             complement(31109..31627)
                     /gene="rimM"
                     /locus_tag="ACL3JB_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0685754.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31697..32445)
                     /locus_tag="ACL3JB_001000"
                     /pseudo
     CDS             complement(31697..32445)
                     /locus_tag="ACL3JB_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            complement(32549..32873)
                     /locus_tag="ACL3JB_001001"
                     /pseudo
     CDS             complement(32549..32873)
                     /locus_tag="ACL3JB_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            complement(33022..33261)
                     /gene="kphA"
                     /locus_tag="ACL3JB_001002"
     CDS             complement(33022..33261)
                     /gene="kphA"
                     /locus_tag="ACL3JB_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0685755.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33281..33553)
                     /gene="rpsP"
                     /locus_tag="ACL3JB_001003"
     CDS             complement(33281..33553)
                     /gene="rpsP"
                     /locus_tag="ACL3JB_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0685756.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33723..33932
                     /locus_tag="ACL3JB_001004"
     CDS             33723..33932
                     /locus_tag="ACL3JB_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685757.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            34411..34632
                     /locus_tag="ACL3JB_001005"
     CDS             34411..34632
                     /locus_tag="ACL3JB_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685758.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            34716..35519
                     /locus_tag="ACL3JB_001006"
     CDS             34716..35519
                     /locus_tag="ACL3JB_001006"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0685759.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35576..37117)
                     /locus_tag="ACL3JB_001007"
     CDS             complement(35576..37117)
                     /locus_tag="ACL3JB_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0685760.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHELDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37119..37601)
                     /locus_tag="ACL3JB_001008"
     CDS             complement(37119..37601)
                     /locus_tag="ACL3JB_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0685761.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(37601..38686)
                     /gene="rlmN"
                     /locus_tag="ACL3JB_001009"
     CDS             complement(37601..38686)
                     /gene="rlmN"
                     /locus_tag="ACL3JB_001009"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0685762.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRGVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(38707..39237)
                     /locus_tag="ACL3JB_001010"
     CDS             complement(38707..39237)
                     /locus_tag="ACL3JB_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0685763.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(39393..39998)
                     /gene="sodA"
                     /locus_tag="ACL3JB_001011"
     CDS             complement(39393..39998)
                     /gene="sodA"
                     /locus_tag="ACL3JB_001011"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0685764.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40171..41208)
                     /gene="holA"
                     /locus_tag="ACL3JB_001012"
     CDS             complement(40171..41208)
                     /gene="holA"
                     /locus_tag="ACL3JB_001012"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0685765.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41242..42177)
                     /locus_tag="ACL3JB_001013"
     CDS             complement(41242..42177)
                     /locus_tag="ACL3JB_001013"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0685766.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
BASE COUNT        12694 a         9287 c         7645 g        13011 t
ORIGIN      
        1 taaagttgta caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt
       61 ctctagtctg gagatttttc aatagacttc gttattggac ggttaccaag ttactcaaag
      121 tacagatttg aagctgcaga taagactgac gaaatcactt taatactaaa tgaaaatcaa
      181 aaagcaaact aagaagctag cctcaggctg tacttgagta cggtaaggcg acgctgacgt
      241 gatttgaaga gattttcgaa gagtataaaa cactgttttg aggtggtgga taaatcggct
      301 gggtaaaaac tcaatctcag gagaaaatga agtaaatctc cccacaacta tagaaaaaga
      361 tttgattctg ctcctcacac aataaaatct ttttctttta ttaaaaacga atcgtttcac
      421 gtgttttctc atatgaggta acaaagcgat tggttacacc aggctctgcc acttccaatg
      481 cttgagaaat cttgtcaaat gaagcgtgat aatcaaattc tttttcaaaa atatctaaag
      541 cttcgttaaa tgcttcttga atgcgttcat caaatgagcg atagcggtta gaatattgca
      601 agagttgctc tgtcaaagtt gcatattgta caatattata agtttccgtt tctaaagctt
      661 ccatatcatt cgttgcaatt tcaagaactc gggtaacaga ttcaatgtta atcatttttt
      721 gttctaactc aaccattaaa tcctcggtat tattgcttgc cgtaaagaat aacttcaaga
      781 aagtttgtgg aatacctggc agattgcgtt tttccatgta tcgcttgata gtatggagac
      841 gattgacata aacattggcc ttttgacgtg cattaatatc atctttctca atttgtgtca
      901 ggcgctcact aactgaaatt tgctcatctt caatatcttt tagttgagtt tgtaaatcct
      961 caagattttc ttcaagaact gaataagctt gggttggttc ttcttgattt gaagttacct
     1021 caacaatagc tgcctcaaaa ctctctaatt ctgtctgaat acgacgaaca tggcttgcag
     1081 ctgtctcagg aagtaaatag gtcttgttca aacgtgcaat atcttctccc aataaagtat
     1141 tattctcttt catatgttga aggtaagttg gaagagttgc aagtagattt tccactactt
     1201 tctgagcagc aatttctcga gtaaaaatat catacaaggc attgatttcc tcttgtgcct
     1261 gtccattctc atattcggca ttatccaatt ccaactgacg aatattctct tggtttttct
     1321 tgaatgcttc ataaagcaag tggaaacgcg cttcaatatc cgtttcaaca aaatgataat
     1381 tagcatcaat tagtttacga taaccggatt ccaaatcctg taattgatct ggcaattctg
     1441 tagaaagcgt cgtaaccaag gctggaacac gatccacaat atgacttaag gccaaaatgt
     1501 gattttctgt attatccaaa atcactgcgg cttccacagg gtcacccgat gaattcaagg
     1561 ttacaaattg tgaaaattca gattggatat tttctaattg tttttcaatt tcatccaagg
     1621 cttgaccata ctgttctgaa ttttcagcaa ctctatgctg aagttcctca aataaatcca
     1681 aagcatgaag aacacgacca ctatttttag attcttgctt ctctaagtct gccaaagcat
     1741 tgcgaattgc cgcaatatct tcttcaatca aagtaatttg actctcaatt tggtcaattt
     1801 gatgactggc cttgagaaaa cgaaatgaat ggttataacc ttctgcttca aagagattat
     1861 tttcaatatc ggcaaaagag ttgagagata aatcgaccca tttttgattc cattcacgga
     1921 aagccacttg actttgtcca atcaagtgca tattttttac agcttctact tcatcattta
     1981 ctggaagatt gtatagttct tcttttcttt cttctagcgc ctctaatctc ccctcgtttc
     2041 gcttacgtag aaagattgcc actacataag ccagaactaa aatgactgca attgcaacca
     2101 ttaaataaat tagttgtcca ttagacatat caaactcctt ttttacttga aacaatcgta
     2161 acgattatat catatttttt agaccaaggg aactacttct ccctattttt tagacatcaa
     2221 gtgtactata gacagcattt tcttcgataa actcacgacg aggctctact cgatccccca
     2281 tcaacatatc aaagatttta tctgcttctg cagcatcatc tacagaaact ctagccatca
     2341 agcgatgttc gggatccatg gttgtttccc acagctgatg atcgtccatt tcacctagcc
     2401 ccttataacg ctgaatagtc ggtttggtac gaccttcact ataacgggct aaagcttctt
     2461 ggagtttgat ttcttgatct gcacccggct ggatatattc tttaatctcg ctcccaacct
     2521 tgacaccata gattggtggt tgggcaatat aaacataacc agcttctagg attggtttca
     2581 tataacgata aatcaaggtt aaaagaaggg tacgaatatg ggctccatcg acatcggcat
     2641 cggtcatcaa aacgagtttt tggtaacggg ctttcgaaac atcaaattct gcgccaaatc
     2701 ctgttcccat ggctgtgaaa agactacgaa tttcttcgtt agctagaatc ttatccatac
     2761 ttgctttttc aacgttcaaa atcttaccgc gaattggaag gatagcctga aactcacggt
     2821 tacgaccaga tttggctgat ccaccagctg agtctccttc gacgatgaag agttctgttt
     2881 cagcagggtt attagaagaa cagtctgcta gtttccctgg aaggttggaa atttccaaac
     2941 cagatttttt acgtgtgact tcacgcgcac gcttggcagc cacacgagcc ttggcagcta
     3001 aaatcccttt ttccacgata cgtttggcaa tctgtggatt ttccatgagg aaatcggaga
     3061 aggcttcact gaagaggcga ttggtaatct tgaccacttc gctatttccc aatttggtct
     3121 tggtttgtcc ttcaaactgt ggatttgggt gtttaactga gataactgca gttaatcctt
     3181 cgcgaacatc ttcccctgtt aaattatctt cattgtcttt cagtaactta ttcttacgag
     3241 cataatcatt gataacacga gtcagtgccg tacggaaacc ttgttcatgc gttccacctt
     3301 catgggtatg aatattattg gcgaaactca tgacattttc atggtaacct gttgtgtact
     3361 gcatggctac ctcaactgta atatcatcca tctcaccgtc tgtatagatt ggtgtatcaa
     3421 agattacatc cttgttctcg ttgatatatt caacgtaact agcaatccca ccttcataat
     3481 gataatgctt ggtttgttcc aaaccttggc gcttatcagt gatagaaatt tgaagaccgc
     3541 gatttagaaa ggccaactct tgaatccgtt tatttaattt atcaaaatca aaggttgttg
     3601 tttcagtaaa gatttttggg tccggtataa agtgaaccgt tgttccagtt ctatctgtat
     3661 ccccaaccac ctcaaggtct gcaacaacat gaccacgacg gtattcttgg taatgaatct
     3721 taccgttttt atggacatga acgtctaatt gagtggaaag ggcattaact actgacgacc
     3781 ccaccccgtg aagaccacct gaaaccttgt atccaccacc gccgaacttt cctccagcat
     3841 gaaggactgt aaagacggtc tcaacagcag gacggcctgt tttttcctga atatcgactg
     3901 ggataccacg cccatcatcc acaacagtaa tcgaatcatc tggctcaata aaaacttgaa
     3961 tatggctggc aaatcctgcc aaggcctcgt caattgagtt atcaacaatt tcccagacta
     4021 gatggtgaag accttctttt gaggttgatc caatgtacat ccctggacgc atacgaacag
     4081 cctctaagcc ctctaaaact tgaatttgac tggcatcata atcctgtgcc tgcagatttt
     4141 tgatttcttc tgtcatctta ttcctttttc ttatatgtct aatacttgtc ttaaattcac
     4201 gatactggta aacaagtggg tatcaagtcc tgcagcttga cctgcttcga tatcaatcgg
     4261 ccgatcacca atgacaagac cagagctaat ctgatacttt tctcttaaat aaagcatgga
     4321 ttcgggattt ggctttctct taaagcctga gctagaagtc accacttctg taaaataagc
     4381 tgctatagag gttttttcta aaatttccaa aacctgatca tttcgatgag agaccaaaaa
     4441 atgacggcca ccttgattta aaatgtcttc caataggtca gaaactcctt caaataaaat
     4501 cgggtgttca agctctctgg cttcattttc cttgtacttt tctaaaaaat tctctaaatt
     4561 gggagcgaat gtctcaatcg caaaaggagt agaaaccttt aaagtttgat agacactgtc
     4621 atggtcttgt gtgataccat acagtgccaa tgtttcaaca aatgcagctg ttgaagtttc
     4681 ataattatcc agtaaagttc cacctaaatc ccagatgtaa tcgtgatatt tcataccctt
     4741 cattatagca tttttttatg aaaaaagcga tgatttccct gagttttcca cataaaaaac
     4801 gagagaataa ctcccgtttt actgattttt accaaagaca tctcgataga gcattcctgt
     4861 tcgtaaactc tctgcgtccc ctcctagttg ctccaccaac tcgtaggcaa aggcaagggc
     4921 tgttgaagga ccccgactgg ttgtcaactg accatctacc actactgttt ccttgacgta
     4981 gtgaccatca aggatttgct cttgaacgcc gtcataacaa gtgtatcgct tatttttcaa
     5041 tatctctgct tgattgaggg caattggtgc cgcacaaatg gctgctagtt tcttcccttc
     5101 ttgttcgaag ctttgcaatt cttgaatcaa ggtctgatta tcacgtaaat gtgcagaacc
     5161 aggcatacct ccaggaagaa caatcatatc atagtctgat aaatctccat caaagacatg
     5221 atctgctctt acttggattg catgcgaacc cgttacttgc tcttcaaaac caaccatatc
     5281 acatgtgata ttggctcgac gcaagacatc tacaactgtc aaggcttcaa tttcttcaaa
     5341 gccctgagct aacataactg ctacttttac catgattttc tccttattta atttgtttta
     5401 atacaacctt tttccgtttg aatgggactt ttccgctctt ttcttcagct agattagtct
     5461 ggtaactcat cgataaaagc aaaccaacac caatcagatt actgataata gctgatcccc
     5521 cttgcgaaat gaaaggcaag ggaatccccg tcaaaggaag tagtccagtc acagcaccga
     5581 tattctcaaa gatgtggaag agcaacatca taatcaaacc tgtggaaata taagtgtaga
     5641 actggttatt tgatttaaga gtaatcttca acatacggta aatcaacatg agatagaggg
     5701 caataaccag gacagagcca ataaagccaa aatcttctgc aataaccgta aaaatcatat
     5761 ctgactctcg aactgggata agcagattcg aagcattaaa tccctgacca aataagccac
     5821 cactcccaat ggcaatctgc ccttgagcct gctggtaagt cgttgtttgg gcaaactcaa
     5881 agggattgag ccaagccaaa atccgattga tttggtaggt cggcattcca atctggtgaa
     5941 gaaaagctcg tccgtccttg ctaataaaga tagctaagaa accagcaact cctgttacag
     6001 cagtcacaaa tactgggata ataattttcc aagaaacccc tgataataaa acgattcctg
     6061 agaaaatggc tacaaaaacc aaagccgtcc ccaagtcact ttgaagtgct aaaagaacta
     6121 ggactggaat ggtaaagaga atcatccaga aaattaacaa aaagtccagc gaaaccgtgc
     6181 gtctccattc cttatgtttc tttgtaaatt ggacaatgac acgagccaac atgaggatat
     6241 aggatatctt cataaattct gacggttgaa atagggtaat tccatttatt gatacccagt
     6301 ttttggcacc cgttgatgca actaagcttg gattataaaa tacaatcggc aagatcataa
     6361 gtcccaagcc taaaatatat agaaaggggg tcaccttcca aagaaattct gtattaaaga
     6421 gcatgaccac aaaaccaatc acaagcccca aggcaatcca ggcgacctgc tgccctaaaa
     6481 tgggcagaat attattggga taatcatgac taacggctat atagatagcc accacaccga
     6541 tgaccagtag aaaaaatact ggcaagagca aactataatc aactctagag tcgagagaac
     6601 gtttcatata tactaacctt atactttcat acaatactat ttatcaaagt tcattaaaaa
     6661 atctatcaat agcctcgtca acttcggatc gagagatggt tttaatagtc gcttcttctg
     6721 ctagagatgc tactatttgt ttgccgtatc gttttccgat gattctccta tccaaaataa
     6781 gagttaagga acgttggtat tcacgtctca tacttcttcc caaagcctgt tttaaacgaa
     6841 taatggccat tggcaattga taatcataaa aggcattttt cccttcttga ttcagttctt
     6901 gattaatctt tttcgtcaag ggttcttgag gattttggaa aggaagcctc ggtacaactt
     6961 gaatcacaaa aggatggctt gaaaaatcaa ctccctccca gaaacttgct gcaccaagca
     7021 agatttgttg ttcacctttt tcaaagcgtt tctttagctg atgaacatcc ccatttttat
     7081 actgggccaa gtggctaact gtaagtaaat ccgatactgc tagaagcatg tctttagcgg
     7141 taaagagaac caaaatcggt tgctggaaag cttgaatttc cactagtaaa gcagctacct
     7201 ctctggcata gacttctaag gaggtttctg ttaccagagg gaaatctttg accataacca
     7261 cttcttgttc ctgttttccc cgagattcaa tcttgacaaa tttggcttca ggatagccta
     7321 aaaggtctgc caaagaaacc ctctgactaa tctcaagagt agccgatact cccaagactt
     7381 ggcaactctc aggaagtaaa gaggacagaa gagtacggca tgattttgta gaagaaatct
     7441 gaattttctt ttgactcgtt tcagttactt caagccagta atcaccttca gctgtaaaat
     7501 agcgaaccag ctcatcaaag ccttctactt ctaattctga aaaatactga tggagattgt
     7561 ccagagaatc taagatattt ttcctagatt taccagactg aaattgttct atcaagtaga
     7621 gacactcaaa gcgaatactt tctagtatcc gttgttgaac cctgttttct tctcctacta
     7681 aagccttatc aattaaatcg ataatagatt gtatatcgta ggtctcttga agcagatttt
     7741 ctagagctaa caaaatcttt tggacttcat caataatcag taaacggtca ctgacaaatt
     7801 caggattatc ttcaagtctg gtcacgagat aggcatgatt agtcactaaa agcttgcaag
     7861 tctctgccct ttcttgacta cgtttccaaa aatcttccgt cacaaataag ctctgggatg
     7921 ataaattccc atcatgacga aggtctgcta gaaaatgttg gtaacggtag agttgcccga
     7981 tttcatccaa atctcctgtc tctgtctcag taagccagac caagacttgc attttaaagc
     8041 gtctaaataa gcgattttca tcattttcct gcaaggaatg ataaaaggca tccaacttca
     8101 gataattttg tggtcccttt aagctatgaa tatctgtatg gaacacttcc ttgaggcgtt
     8161 taccttcttc ttccatgatt tgattttgaa gaatctttgt cggaacacta agaacaattt
     8221 gtcgctcttt ggattgagat aaagcgggta agagatagcc ataggttttc ccaatccctg
     8281 tcggcgcttg aatcagagag acaggttcat ctttcaatag caagccaacc tctttagcaa
     8341 aactttcttg ttcctccctc acttcaaggt tcaacagaga aatattttta gaaaagtctt
     8401 gagatagttt tcgtggctcc agagaagctg ccgttttctt aaaatacaga ccttgaactt
     8461 ggaccaagtc tggagaactc aggatagatt ggttgcgata agtttcctca ataaccaggt
     8521 aggactcata taggagagcg tcagccattt ccagcaagcg ttccaagaga cctttaggaa
     8581 gctgagtcat cttttcccgt aaaaaaagaa gtaattctgc tgtagcttgg gcatctgaaa
     8641 gggctgtgtg tgcgtgttta agaggaattc ctaattctcg acacaaaatc ggcaagctat
     8701 atttttccag ttcagggaaa aagacctggg ccaattcgac cgtatcaaca cgagggtttc
     8761 ttagctcata gccttcaaaa aataaatttt ccgccaagag attagcatca aactgaacat
     8821 tatgggctac aaaaatccca tcctccacca agtcaaatat ttttctggca acttgcgaaa
     8881 aatcaggtgc ttgcgccaga cgttggtctg tcaatcctgt cagttctttg atatgaacat
     8941 ccaagggttc atgtggattg acatccgtcg tatagtgatc gacgatttct ccgtcctcaa
     9001 tcacgacaat tcccacttgg ataattttag ccttactacc tgtgctagtt gcctctaaat
     9061 ccaccacaac atagcgatta ccaatcgttt tcattataaa aaattatacc aaaaaaaggg
     9121 ccatttggca cctgcaaaca taggataatt ttcaaactca agaacactac ttttcttaaa
     9181 aatcccatcg aatagagcat tctagcctgc tgatttttgt aaaatagtga agaaatacga
     9241 aaaattgaga gaagaaatgt ttgcatcttc cttctctcaa cgaatcatgt attttatcta
     9301 accatgtcag gatcgtagtc ataaaatcct gtatcaagga aacggttttt agggtgaagt
     9361 ttacgaactt cttcatccag caagaaggct tgatcatggc taaagttgcc ctcttgaatc
     9421 caattacgcg cttggataaa gagttttgca atctcaacaa agttctgacc aggagtgtag
     9481 agcccttcta gtttccagcg agtaaagcca tgctccacca attctgttaa tttgatcatc
     9541 aaatcaaggt cattgttggc aaagatatgg gtcccatgat tatcttcaaa aatggaatag
     9601 tggctctctg gatcacttgg ctcagccaag aagaggtcac gtttatgcgt cttttcatca
     9661 tcgatatgtg taaagttata gtagttttgc aagagtggac gtttagaatg atggatgacg
     9721 ctagcaccgt aaaccaaaac ttcagcagga atttccaaaa tctctggcat tttgaaaagt
     9781 tcagctgatg gaatttcacg cgccaaaaca gcctcagatg cgccagcctt ttgtccccag
     9841 aagttaatct gacgactgct agttaccatg gttgaagcat cgtagatggt cttaaatgaa
     9901 taaccatcgc ggttaactac gtaaaagacg cctgcatccc caatcgtaat atagtctgtc
     9961 ttgatttctt ccaagaagtc taagaaaggc ttgatacggt ccatcatatc ttggtgcatg
    10021 agagcattga ccgcaacgag caattcctta ccagcatcat gaaccaactt agcgatttca
    10081 cgtaattggt cataactaaa ggtcgttggc agacgaaggc caaaatcttt ctcaccgaca
    10141 tagatacggt ctacgccagc ttcgagtagt tgttcaactt gttcaatact ttcagcagtt
    10201 gctgtaatga caatcttttc cataagaaaa attataccac atttctccaa aatcagccat
    10261 gctttgaaaa tgaaaaggga ctttattctt tttgtaacct ttctgtaata attctctgcc
    10321 gaaaaaatga taaaataggt atgtactgtt aaggagagaa ttatgcccgt aagaaaatta
    10381 caatcctatg aggtagacta tcaagaagaa ttaaaccagc agcttcctca ttaccaagct
    10441 tatacacctg aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt tattaatatc
    10501 gctgtttttt gtatctgtat tgctatcttt agttttatct ttttagcatt aaaattatca
    10561 actgctcttg cctttgccgc agcaatcgga ttcagcttac ttgttttaaa agttcaacgg
    10621 tctattatca aacgaaaacg tagaagataa atccaaaata tcgccccagt tggagcgata
    10681 tttttatttt ttctttttag atggtgtctg aatggcaatc ttcacttcaa agattgttcc
    10741 cttgggttta ttatctttga cagtaacagt tccttttaga gcatctacaa tttgcttggc
    10801 tagggataat cctaaaccaa aaccaccttt ttgccgagtt ctagccttgt ctactcgata
    10861 aaaacggtca aaaattttct ttttatcttc tgtcgaaata ccgattccat tatcagaaac
    10921 aagtaaataa agattgcgat cggtcgccga gataagaaaa tcaatttcac catcctcctc
    10981 agtatacttg acggcattat cgaaaagaat ggtcatcagt tgtttcagaa gaagctgatc
    11041 tgtgacaatt gttcgatgga tacgattttc aaaacggaag acacgattat tttccgaagc
    11101 aatcatctcg tagtttgtga aagttgtatt aaaaaagcta gttggaactt ctgcaagctc
    11161 cggcttaatc ccatcatctc tccgagctaa gttcagcaag cttgtcgtta aaaaacgcat
    11221 atttcggact tcttccaaac tcgatgcaat gctttcgctc acatccataa tggtagcttc
    11281 tggcttacga aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag ttcgtaactc
    11341 atgactggca ttttccacaa aagactgttg cttctgcata ctctcaagca ggggcctaac
    11401 actgacccta gctagataga gactggcaag taaagacaaa atccagaaac tagccatcac
    11461 gaccacaatc aattgctcat gcttttgact agcctgctcc aactgactgg tattaatcaa
    11521 gacagcagca tacttgatat tggttgaaac cgaactaata ttggtctcca tcaaaatcac
    11581 acgatagatt tcttcctgcc catagctatt aaaaacctga atctggtaga tatgtcctag
    11641 ttctttcttt tctaacttaa tcttatccaa gcccaaaaat cgatttccag aaagaagttg
    11701 agtaaagtcc ttatcaaaga gaatgacttc cgtattggaa ctgacattag gttttatttc
    11761 tactttacta gcgtccgccc tagcattttc taaatcttta atctcttctg ttgccctatt
    11821 tatagccagc tgaataactg cttgaggatt ttcactcagt ccatgaagct tatcgtccac
    11881 cgaagtataa agactcgaat gcatgacttg taaaataatc agagtcattg tagaaaaaat
    11941 cagggtgaag acaccgaagt tgcggataaa ataactaaag tcatccgcat accatgtttt
    12001 tttaagttta ctgaacatct tttaaaagat acccaacact acgcaaggtt tgcaaattct
    12061 ctgcaaaagt ggttcccttt aatttcttac ggacttttga aacatagact tcgacaaccg
    12121 aaatcgttgt atcactatca aatccccata gacggtcaaa aatctgcgtc ttaggcaaaa
    12181 tcacattttg attttgaagg aaataaacta gtaaatcgaa ctctttcccc agcaattcga
    12241 caggagtatc ttcaacttta acggtattgg ttgataaatt aaccacgata ttcccataag
    12301 tcaaggtgtt ttcattaaac ttccctgaac gtttgagaag ggcctgaatc cgcattttaa
    12361 gttcttctag gtagaaaggt ttggtcagat aatcatccgc tcccagttca aatccatgtc
    12421 ccttgtcatc caaactttcc ttggcagtca taatcagaac tggtgtcgta attccctttt
    12481 cacgcaattc ttttaagact tggaaaccat ttttttctgg caacatcaaa tccagcaaaa
    12541 tcaaatcata gacaccactc tcagcttcgt agagaccttc ttctccatca aatacctgca
    12601 taacatccgc aaaatcgtct aaaaagtcaa atactgaatt tgacagacct aggtcatcct
    12661 caaccaataa gatttttatc atgagaaact cctccttatt aaaactatta taccaaattt
    12721 gccttaaaaa aaactcaact ctctgcattt tacatgagat agctgagttt tctttttatt
    12781 ttaggcttat ttatgcattt ccgtattgaa gaacaactgc ttcgactgca gctttttcac
    12841 ggctaatcaa gtcaacacgt gctgcaattt ccttgattcc cataccgatg ttacggctaa
    12901 gagcaaggtc agaaagttgc ggctcaaaga actccttgta ttccgccaag cgttgctgag
    12961 tcttaaatac atgagcagga aggataacaa agctatcaaa gctcatatct cctccaaggg
    13021 ctgccttaat ccaagcccag ttttcacgcg cccaagacca agctgttttc tgagttgctt
    13081 gatgagctag gaattggtaa taccaagcag acaagtcctg tggtttgacc acaaatttgt
    13141 ccttccaaga agtaatcaag ttttggatat tatccgcatc tgtactgtat gcaagagctg
    13201 ctgccaactg gcgtttaaag acagcatctg ttgcgtgagt ataagtatca agataaagtg
    13261 ctaacaagtc tttagtctca tgatgtttca tctcattaat cagaacttgt gaacgaatag
    13321 ctgctgggag tcctgcaaga ttctccttgt gtgttgcgaa gatttggcta gcgacttgac
    13381 tagcttctgc atcatttgag cgaatcatca tcgaaacagc cagctgacga accaattcat
    13441 cctcatctga ttctccgtct ttagcttcaa aaccaagacg gtcatagtta tgacgagcca
    13501 atttagcaac cagtcctttg aaggctgttt cagcatccgt tccttcatca ataaagcgct
    13561 caagggctga aatcacttga gaaacagctg aaaccaccag ataagactct tccttagcaa
    13621 gtttatcaag aactggaagc aagtctgcat aagaaatgtg ccctgcctca gccaacaaac
    13681 gacgttcttg aacaatttgc agtttgcttg tgttatcaag tgtctctagc tcagcaagaa
    13741 cagcttctaa caagtctcct tgatagtcgg taatatagtg ggcagtattt tcagtgttga
    13801 gacgaagagc tccttcattt tcagcaagaa gagctgcgta gccagggatt tcgatacttt
    13861 cagtttcgag tgtatcaggc aagcctttcc agttgctatt gaggggcacc acccagagac
    13921 ggttcttgtc ttcgttctca ccgatgaaga attgtttttg tgaaatcttc aagacatcat
    13981 tttcaacttt aacagtaaga actgggtaac caggctgttc caaccaagaa tccatgaagg
    14041 ctgcgacatc acgtcctgac gcttgaccaa gggcatccca aaggtcacta ccaatggtgt
    14101 tgctgtattg gtgtttttca aagtaggcgt gcaaaccttt agcaaaatca gcatctccta
    14161 gccaacggcg aagcatgtgc atgagacggc ttcctttggc atagacgata gcgccgtcaa
    14221 agagtgtatt gatttcatct ggatgtttaa cttcgacgtg gacagactga acgccatcag
    14281 tagcgtcacg ttcaagagca agaggtactc cacctgtttg gaaatcttca aagatattcc
    14341 agcttggttc gatggtatcc acacagacgt attccatcat attagcaaaa ctttcattga
    14401 gccaaaggtc atcccaccat ttcatagtca cgaggttccc aaaccattgg tgagccaatt
    14461 catgggccac aacaagggca acttgttgac ggctagcaaa tgtagagttc tcatcgacaa
    14521 ccaagtaaac ttcacggtag gtcacaagac cccagttttc catagcacca gctgagaagt
    14581 caggaagggc gatgtggaga gattgaggaa ttgggtactt aactccatag taatcttcgt
    14641 aaaactcgat agagcgaaca gcgatatcca gtgagaaatc aagatttgaa agtggatgtg
    14701 ctttggttga gtagacacct accagggtac catttttagt tttagcggtc accccttgca
    14761 aatcaccagc aacaaaggcc aacaagtaag aagacatgcg aggtgttgtc tcaaacttcc
    14821 agatacctgt ttccttacgg ttttcaacat cgatttctgg catgtttgac aaggccaatt
    14881 caccttctgc ttggtcaaag cgaagagaga ggtcaaaagt tgctttggct tcaggctcat
    14941 ccacacatgg gaaagcttcg cgcgcaaaat ggctctcgaa ctgagtagac aagacctcct
    15001 tcttgactcc atcaactgta taataagaag ggtaaatccc tgtcatgttg tctgtaattt
    15061 taccagaaaa ggcaagaacc aattcaactt gaccagcctc agccaattcg atatgaaggg
    15121 cttcattgtc atggtcaact gtaaatggac gagcttgacc tgcaacttct acagaggtga
    15181 tttccaagtc tttttggtgg agggagatgc ggtcactctg tgcttgacca gtgatggtca
    15241 ctttcccaga aaaagtcttg gtctcacgac tcaaatctaa aaataaatca taatgttcag
    15301 gaacaaattg cttaataaaa tgttcaactg cttgcatagt tttctcctat tctaagttta
    15361 agagctgctg ctcttcttca aacaaactta ttatatcata ttttgcttga gaaaaaagga
    15421 ttggacagcg atttccaaaa ctttcttcct tctaatagtc tacagtgggt agaccttgcg
    15481 aaattcttct aaaacaacct tgctttcagg tgtaaaagtc agccctactt cacccaaaca
    15541 gtctgtgaaa aagtcctcat gagcctggcg ccaataggca agtgatttgt ctccctcacc
    15601 ttccttaaag gcatgttgcg cagagacttg attgaagagt tcaacagaaa cctttgtaat
    15661 ttcgacaatg cagacagact gattttgact atctaaaatg acatcgaagg tccctacttg
    15721 gggaagtggt tcgtcttcta gtacatagag gtcataggct gatgctgttg ctgtcttttc
    15781 tcctttaaac accaaatccg ctaaaaggtc tggttcaact ccaaaagccc aagcatcgat
    15841 ttcatctccg atcaaaggat tgatttgctt gtatttattc cacatttctt gcggtatcat
    15901 gggtactcct ttgtaatttt ttactttctt cttttatgtg tttaagatga tctggatggt
    15961 caatctctaa atcaaaaatc tctggaatag aactgtagtg gataatgcac ttgataccca
    16021 actgattcat tttttgtatg aaagaagtat tcagatagcc tgctacagca aaattaatct
    16081 tgttctttct tgctttatcc tgcatatctc ttagcatatc taacattatt ggactttcca
    16141 tatcatgcca ttgactgttt ctcatagtcg caaaaacaaa ggaagtcaaa tcattcattc
    16201 caactacaat ctttgaaatg cccgtttcca gtatactaga taagtcaaaa tacgctgacg
    16261 gtaattcaat catcgttccg actttcccag taaagccata ctgacgcaat actgtaatag
    16321 cttgttttaa ttggtcggca tcattgacag aaggaaagat aacagataga ttggggttgg
    16381 tttgataaac ttctgtaacg acatgtgctt cagcctgaaa ttcatccaaa cacgccagta
    16441 aacgtctggt tcctctatag ccaaacaagg gatgcccttc gtcaaaaaac tctctagtcc
    16501 ccactaaaca attggcttct gtattcgtta attcagaaaa acgataccaa acttccttac
    16561 ctaagtaaaa ggagcaaata gtatcaagat aatcttttac aaattgctga caacttgcta
    16621 atatgatgtt ttgattgagc tctctcaata agtattcccc acgaatcatg ccgacgtggt
    16681 gaaatagttg aggataaatt ttttcaagaa ttttttcgcc actaagggca agttgatttc
    16741 tcatagccat tcacctcgtc ttaaaagata caatatcata tataattata tcaaaatttc
    16801 ctctagttca aaagcttcat aaggttcaga taactcatat cctaaaaatt ctgctacttt
    16861 tttggaagcc tcattatgag catcccaaag tggaaacata tctctattta aactctctag
    16921 aatcattgca gcaccaagct ttttagcaag tccatttcct tgttcgtttg gtctagttgc
    16981 aacttccact tcaactgctt tacggtaaac taaccctgag gaaatcccag caatcagttc
    17041 attattttta agaatcacaa agccaaatcc accttttaaa acaaaatcct gataggactc
    17101 aaaatccccc tgtaaatcct gtgaccattc ttccgtagaa aagcagttat aaatatgatt
    17161 atcaataggc acaatattgt aaccttcctc taaatgagta actagattat ttaaaaattc
    17221 aacttgaaaa tttgccttat ctttaaaaga atagcgagta aaagaattta gccccacttt
    17281 tcgatgcaga aaatcttgcc aattagtatt ttctgaaata ataatcttat aatctaaacc
    17341 atattttcta acaaaatctt cccaaaatct ggaatccaac tcccctgcta ggtatagaaa
    17401 attcccaaca tcataaaagc ttgttgtcct atcattgttt cggtagacag ttccaatttg
    17461 agatttaaga ccatagagaa ccatattttt cttccatgtt ttaaatagtt ccattatccc
    17521 tctacttcac cttccaattc atgtaagaag tcttgtccag ttctggaaat cctaataatt
    17581 cagacttaac cttcaagact aatggcgatg cattttcttc tgtaatttct tgaatatcca
    17641 tccaaatata tccaagtgaa tcattcgcac catcagacac agcttccgaa gtcgtaactt
    17701 gaggtgcact ctcattcatt tcaacatcat acaaggccat gacatggtga accataaaat
    17761 ttgttaactc ttctctgacg aaaacatcgt agattcgagg attagagtag cttctaacag
    17821 taaatcccgt ctcttccata acttctctag tcagcgtttc cgtcagtcct tcaccaagtt
    17881 gctgactgcc tccaggtaga tcataccgat gttgataagg gcctctcgtt ttttcaatgc
    17941 aaagtaactt tccattttca aagcaaacag cgtagactcc aaagtgtttt ttgatttcca
    18001 tccaactcct cctacttcaa agaccagcca ccatctattg tcaagatttg tccttgcatg
    18061 gcgctcgctt ttccacttgc taaaaaaaga ctaagctctg ctatttcctc tggctcaatc
    18121 cagcgcttga ttggggtttc actagccacc cagtcagcca aaccacctgg ttcaaaatcc
    18181 gcagcggtca tagctgtctt gactgctcct ggagcgatac caaagacctg aatcccagct
    18241 tcagcatagt ctagagccaa ctgcttggtg aagccagcca aggcatgctt ggatgaagta
    18301 taggcgtgac cacctccacc tgctaggcta gaagcaatgg aacacatatt gatgatgatt
    18361 ccctttttat tttccagcat ttgtgtcaaa taataccgag tcaactctac tggaataatg
    18421 tagttgattt caaaaatctc ttgaatgtcc tgcgccgttt gttccaacag tggtttgtaa
    18481 tcatccaaaa ctccagcagt attacacaaa acatccacct gagggcacca gtcaaaaata
    18541 ggttccaagt ccaaggtcaa atctctctgt aaaaagtgaa aatcaccctc taagagtggc
    18601 ttttcacctt ggtcaactcc ataaacttga tagcccttct ctaaaaagag gcgagcttga
    18661 gccaatccga tccctgaact cactcctgta atgagtacac gtttagtcat gcacttctac
    18721 ccaatccgtt gccaaaacat cacaaactgt cgggctccac atggaaaaac cttctccttc
    18781 gccagaaacg ttgattagga aataaggtgt catttcaagt gcaagcccat tttgctcgat
    18841 ggtatcaaag agttggacat agttttccgc acctccccaa ccagttcgta catattttct
    18901 cttagccttt aacccaggca ggatctcttc aaatgtcatg tttttctcct ttaattctac
    18961 attcttcatt taattatagc aaaaaaccgc tttatacggc tttttgaatg tgagttattc
    19021 aaacctgcta ctacttacgg caaattattc cctgcagcaa gataaatttc ataccattct
    19081 tttcttgtta agctaaagtt tgccgcttgg ctaacttctc tcaagtgctt aggatttgtg
    19141 gtacctacaa ctgcctgcat ttttgctgga taacgcaata tccaagaaat ggcaatagtt
    19201 gaagaggtta ctccatattt aatagctaaa cgatcaagta cttgatttaa agcttgaaat
    19261 ttctcatttc caacaaaatt ccctttaaaa tacccgaatt gtaagacaga ccatgcttga
    19321 atgaccacat cgtgtaattt gcaatattca aaaatgctgc catctcgcat agctgcttga
    19381 ctatcttcca tattaacatg aaaagctgat tcaaatcctg gagtaaaagc cacactcaat
    19441 tgtagctgat taacagctaa cggctgcttg acatcttttt taagcaactc catcatcata
    19501 ggattttgat tagaaactcc aaaatctcga actttacctt gtttataaag gagatcaaag
    19561 gcttctgcta cttggtcaga ttccatcaaa gcatctggtc gatgaaggag caagctatct
    19621 agatgatcaa tcttcaatct ttgcaaaata ccgtctactg attttataat atagtcctta
    19681 gaaaaatcaa aataggtaaa ttcttcaatg cgaatgccac atttggactg aatccacatc
    19741 ttttctctta aatctggacg attttttagg acaagaccta acagttcttc acaacgacca
    19801 cgaccataaa tatcagccaa gtcgaaggca ttgattccaa cagaaagtgc tgtttctaca
    19861 aactcttcaa cttcttttac agacttatct tttattctca tcattccgag aacaatttct
    19921 gataattctt tgtcatcttg accaagagtt atgtatctca tcaaattttt ctcctttaat
    19981 ttctaacatt cttcccttca ttataacaaa aaaccgcttt gcaacggctt tttgactata
    20041 cttcactcca ttttatcttc ttaaacccat ggaacaagag aaaaatgcca ataaagagga
    20101 cagctaaagg aataactttt gtaaggaaaa catttgaaat tcccatccac tcataataac
    20161 ggagcagaga acccaccaca agatgggcaa taatcatact gacaaatgga cgaaagaccg
    20221 cttctttcca attccaaata ccgataacta gcgaaatcgt aaagacagac aaactatccc
    20281 agggatccgg aatataaaag gctccttctt gtatgaagct tgccattcct acatatccta
    20341 aaacaactag aagaactata gtcccaacaa caatgtaagt gccaaatttc attttaggag
    20401 aatcttggac taaacttctt cgtaaaattg tggccacaag tccaaatcca atcagaaaaa
    20461 taagaagttg ccctaaaaat gtgagcaaat tgactgttaa gagaggacct ttagaaaaat
    20521 cacttagtag ttgataataa cgtaataccg ccaggacaag aattggcgtc aaaagggact
    20581 ctttgataga actgcgaggt gctcccttga gaatctcttt cattattttt ttaggattct
    20641 tacctagata atcctctgca ctcatgccat ctcgttctgc ttctgagaaa tctagcatca
    20701 tcaaatagat ctgctctctg agatagtctt catcatagag aaatccagca agattaaaac
    20761 tttcccacaa ctcctcaaaa tacttttgat tctcctcaga aaactcatgt agcaaagcgc
    20821 ttgtttcttc gtaatacttc attttcttca tggtttaacc cccattctta atcccttcta
    20881 ctttttgact caaatcgtcc cattgttgcc aaaagactga gacacgctct tctccttctt
    20941 tcattaatga aaaatacttc cgatctggac catctggcga cgggcgcatg tcgcctctta
    21001 tccattgatt tttttctaac ttttgcaaca aaggataaat agttcctgga acgatagtat
    21061 caaatccagc ctctcgcaaa gtctgaacca actcataacc ataccgctct ttttgaccaa
    21121 tcatatccaa gacacaacct tcaagaacac cttttaatag ctgagtttct ttcatcactt
    21181 ctcccttcta atctattttg taatacctac tagtaacttc acctatagta tattacttct
    21241 acactagttt gtaaagcata atagttaata ctcttcgaaa atctcttcaa accacgtcag
    21301 cgtcgcccta ccgtatgtat ggttactgac ttcgtcagtt tcatctacaa cctcaaaaac
    21361 atgttttgag ctgacttcgt cagtttcatc tacaacctca aaaacatgtt ttgagctgac
    21421 ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacccgcgg ctagcttcct
    21481 agtttgctct ttgattttca ttgagtataa ataaaaaaac agaactagtc tgaactagtc
    21541 ctgtctactt ttacccaatc acacttccat ttggtacagc tggatcaact gtgagaaggg
    21601 ttaatttgcc atcatgttca gctgagagaa tcataccctg gctgacatat tttttcatca
    21661 ttttacgtgg tttgaggtta gcaacgattt gaactttctt gccgaccaat tcttgttcat
    21721 ttggatagta ttttgcaatt cctgaaagaa tctgacgatc ttctccatca ccagcatcca
    21781 agcggaattg aagcaactta tctgaacctt ctactttaga cacttctttg acttctgcga
    21841 cacggatttc aaccttgtca aagtcttcaa acttgatttc atccttgttt agtttgagct
    21901 caacttcgtc cggattccat tctttttcga ctgctggttt attgccttcc atttgttcct
    21961 tgatataggc gatttcttct tccatattta gacgtggaaa gataggtgtt cctttggcaa
    22021 ctacagtcac atctgctggg aagtcagcca aactcaagtt ttcaagacta gaaacttctt
    22081 ccaaaccaag ttgagtcaaa actgcacgac tagtttccat cataaatggt tcaatcaagt
    22141 gagcaactac acgaatgctg gctgccaagt ggctcatgac acttgccaat tggtcacgaa
    22201 gagcttcatc cttggccaag acccatggtg cggtctcatc gatgtattta ttggtacgag
    22261 agatcagagt ccagactgct tcaagcgcac gtggatagtc aactgcttcc atgtgtgtat
    22321 ggaagtctgc gattgattgt tctgcaacct cagcaagaac atgatcaaat tcagtcacac
    22381 cttctacata ggcagggatt tgtccatcaa agtacttatt aatcatggaa accgtacggt
    22441 taaggaggtt cccaaggtca ttagccaatt catagttgat acggccgaca tagtcttcag
    22501 gagtaaaggt tccgtctgaa ccaactggaa ggttacgcat gaggtagtaa cgaagtggat
    22561 ctagtccata acgctctacc aacatttcag ggtaaacgac attccctttt gacttagaca
    22621 tttttccgtc tttcatgaca aaccaaccat gggcaatcaa acgatcaggt aatttaacat
    22681 ccaacatcat aagaaggatt ggccagtaga tagagtggaa gcgaaggata tcttttccta
    22741 ccatatggaa gactgttcca ttccagaact tgtcaaagtt accatgttcg tcttgagcgt
    22801 agccaagagc tgtcgcatag ttaagaaggg catcaatcca aacgtagaca acgtgttttg
    22861 gatttgatgg gacaggcact ccccatgtaa aggttgtacg agataccgcc aaatcttcca
    22921 agcctggctc gatgaagttg cgtagcattt cattaaggcg accatctggc gtgataaatt
    22981 caggatgagc tttgaaaaat tcgaccaaac ggtcttggta tttgctaagg cgaaggaagt
    23041 atgattcttc agaaacccat tcaacctcat gacctgatgg agcaatacca ccagtcacat
    23101 ttccagcttc atcacggaaa acttctgcca gctggctttc tgtaaagaat tcttcgtctg
    23161 atactgaata ccaaccagag tattcaccca agtagatatc atcttgagca agtaagcgtt
    23221 caaagacttg tgcgacaact ttttcatggt agtcatcagt tgtacggata aatttatcgt
    23281 atgagatatc tagtaattgc cagagttctt taactccaac cgccattcca tcaacatagg
    23341 cttgaggtgt aataccagct tcttccgctt tctgctggat tttctgacca tgttcatcaa
    23401 gacctgtcag ataaaataca tcgtagccca tcaggcgttt gtaacgtgct aggacatcac
    23461 atgcgatagt tgtgtaggca gaaccgatat gaagtttccc agatggatag taaatcggcg
    23521 ttgtaatata aaaatttttt tcagacataa tttttccttt ccaggcaaat gaaacctgtt
    23581 tttctaacac ttcattatat cacattttta atgaatttca atagggaaat ccatacaaaa
    23641 acaagataga cgagtgtcca tcttgttgat ctcattcata acgaagggct tcaattggat
    23701 caagtttcga tgccttgttg gctggcaaga ctccaaaaat cataccaaca ctagccgaaa
    23761 ctgcaagact aaatagggcg actgggattg atactccaac ttctatacct tctattaaac
    23821 cttgcagtaa caaacctgct aaggcagtta aaccacttgc aattgtcaag ccaattaagc
    23881 cacctaacaa ggtcaaaatc atggattcaa tcaaaaactg aattaaaata ttggcacgtg
    23941 ttgcacccaa agccttacga agaccaatct cacgagtgcg ctctgtcacc gaaaccagca
    24001 tgatgttcat gacaccagtt cctccaacaa agagagaaat ccctgcgatg gaactaataa
    24061 tcgtcgtcat aaaactaaac gattgttgaa tttctgcaaa tacaagggac tcatctgcca
    24121 cctggtattc tccctgttgt aagcctgcaa gctctgtcat ttttcgtgcc agttctggac
    24181 ccagagttgg ggttaaactg gtatcattca ctcgaaagac aatactagct atttcatcta
    24241 cattaaaatt cgcagcaagg gagatattgg tagtaatagg caagccacca aacccatata
    24301 tttttgatct tttagcctcc ggactagtat aaaccccaat gacccggtaa ctaaatccat
    24361 tgacttctac aaccttgtta atagcctctt gaggagattc aaataaacta atggacaatt
    24421 cctcatctag caaaataaca cttgcaaact ctttgaaatc ttgctctctc agactacgac
    24481 ctgcaataat ttcattctta acagcgtcca tgtaagttct gtttccacct gtcaaattag
    24541 cattctcaac ctttttatct tgataggtca agatggcatt cgttgaattg gttacatagt
    24601 aactatccac tcccttcagt ttagctgcct cttggaccca ggattcttgc ggttttggcg
    24661 gttcaacagg aacttcctct tcctttccag aaaccgtaaa agctgattgt ttctgagtaa
    24721 aagacccatc tttacttttt ttaggagaga aaaagacgct aatatttttc tgagatttag
    24781 tcatatcttt attgacttga cgagataggg aatcacccaa agccataatc acaacaactg
    24841 atgaaacacc gataataatc ccaatcatag taagcaaaga acgcatcttg tgagccatga
    24901 tagatgaaaa ggcaaatttc agattctgca tcttagtttt cctcctttcc taactgagca
    24961 ctgtcagacg aaatgacccc atcccgaatg acaatctgac gtttggcata ggcagcaatc
    25021 tcaggctcat gcgttaccat gataatggtt tttccttctt tattcaaatc aaccaataat
    25081 tgcataattt ggttacctgt tttggtatcc aaggctcctg tcggttcatc cgctaggata
    25141 atagaaggat tgtttaccaa ggcacgcgca atggctacac gttgcttttg accaccagat
    25201 aattctgaag gtaaatggtg actacgttct gtcaattcaa ccttgtctaa atattcctca
    25261 gccaacttgc gacgttttga agacgaaact cctgcgtaaa tcaagggcaa ttctacattt
    25321 tgcagagcat tgagcttcga tagaagaaag aactgctgaa agacaaaacc gatttgttgg
    25381 ttacggacct tagctagttg tttttcacca agcccagcca cttcttgacc ttcaagataa
    25441 tattctccac tggttggtgt atccaacatg ccaatcgtat tcatcagagt ggacttacca
    25501 gacccagatg gtcccatgat ggctacaaat tcaccctcat tcacttctag attgatattt
    25561 ttgagaacct gcagttcttg gtcaccatta cggtaacttc tgaagatatt ttttagacta
    25621 attagttgct tcatcagcct tcacctcttt tccttcttcc aaggaagatg ttggattact
    25681 gatgacctta gcaccgttcg ttaaaccaga agtgatttct tgattttctg cgtcagcatt
    25741 tcccaatgaa acctcaactt ttttagcctt ttgttgttca tccacaatcc agacataatt
    25801 tttactatca tccattacta gactgctaac aggaacaaga atagccttag ttttgctttt
    25861 aacctcaatg ttgacagaaa aaccttgttt caaatcacca acctcgcctg tcacatcaat
    25921 agtataaggg tatttagaac ctgtattatt cccggctgct ggactagctg cttcaccatt
    25981 gtttttagga tagtcagaaa tatagcttaa tttcccagtc cattttttat caggatacac
    26041 tttagaagta aagcttactt cttgacctac agaaaggttg gctagattgt actcagacaa
    26101 ttctcccttg acttgtaaat tttcattgct gacaatatga accataactt gactcgcccc
    26161 tgttggagat ttagaaacat tgctattgac ttcgactaca gttccctcta gggtactgag
    26221 aacagttgtt gcatccaatt gactttgagc cttgcttaat tgcgctgcag catctgcacg
    26281 cgcatcacgg gcatcaccca attgagcatc aatagaagca acagaatttc cagccactgg
    26341 agttgggctt tgcaccgttg catcttctcc tcctactggc gctggtaact gtggagcctg
    26401 agctgaagcg gcttcatttc gtgcttgatt gagttcattg atatgacgat ctgccttagc
    26461 tactgctcga ctagctgaat cataggccgc ctgcgcttct gaactactgt acttgactaa
    26521 agcctgccct tcgctgacct tatcgcccac agaaacaagg atttcatcta aatcaccctt
    26581 actagcatca aaataaacat attgttcatt ttttgctgtt actgtccctg acaataaaac
    26641 agaggatgcc acgcttcctt ccttggcaac aacaagatga gtaggctcat cttttagagc
    26701 agtctgagaa ggttgtctaa aaagtaaaat ccccccggca cccaatacaa ctacactcgc
    26761 agcaccgatt gctgcataca gttgccactt tttagcttta ccattctttt tcttcataat
    26821 gaaactcctt ttctttttta caatactttg ctattatacc aaatttccct ccagcaaaca
    26881 atgcagttca gatggaaata atggcagttc aggattaaac aatcgttcgg aattttgctt
    26941 ttctattgta ctagatatat aatacactat cttgacttat ttggcaagct tttttgcaat
    27001 tttttgtgcg tagcagattt ttgcaatcaa atcaaaaaaa gaataaaata taactatcaa
    27061 aaaagacgct ctactattta aaagattaca aaggagtttt caatgagaga atatgatatc
    27121 attgctatcg gtggaggtag cggaggaatc gctaccatga accgtgctgg tgaacatgga
    27181 gccaaagcag ccgttattga ggaaaagaaa ttaggtggaa cctgtgtcaa cgtcggttgt
    27241 gttcctaaaa aaatcatgtg gtacggggcg caaatcgctg agactttcca tcaatttgga
    27301 gaagactacg gctttaagac tactgatctt aactttgact ttgcaaccct acgtcgcaat
    27361 cgtgaagcct acattgatcg cgctcgttct tcttatgatg gtagttttaa acgcaacggt
    27421 gtagacttga ttgaaggtca tgctgaattt gtagattctc atactgtaag cgtaaatggt
    27481 gaactgattc gtgctaaaca tatcgtgatt gctacaggtg cccatccaag tattcctaat
    27541 attcctggtg ctgagctagg tggctcttct gatgatgtat ttgcctggga agaacttcca
    27601 gagtcagttg ccattctagg cgctggttat atcgccgttg aattagctgg cgtactccac
    27661 acttttggtg tcaagacaga tctctttgtt cgccgcgatc gtcctttacg tggttttgat
    27721 tcctacatcg ttgaaggttt ggtcaaggaa atggaaagaa caaacttacc acttcacact
    27781 cacaaagtcc ctgtcaagtt agaaaaaact actgacggca ttaccattca tttcgaagat
    27841 ggtactagtc acacagctag ccaagttatc tgggctacag gccgccgtcc aaacgttaag
    27901 ggcttgcaac ttgaaaaagc tggagtgact ctgaacgaac gtggctttat ccaagtggat
    27961 gaataccaaa atactgttgt tgagggactc tatgctctag gtgatgtaac gggcgagaaa
    28021 gaactgactc cagttgcaat caaggccgga cgtaccctat ctgaacgtct ctttaacgga
    28081 aaaactactg caaaaatgga ttactcaact attccaactg ttgtcttttc acaccctgct
    28141 atcggaactg ttggtttgac agaagagcaa gctattaaag aatacggtca agaccaaatc
    28201 aaggtttaca aatcaagctt tgcatctatg tactcttctt gcactcgcaa ccgtcaagaa
    28261 tcccgtttca aactcataac agctggttca gaagaaaaag ttgtcggact tcatggaatt
    28321 ggctacggcg ttgatgaaat gattcaggga tttgccgttg ctatcaaaat gggagcaacc
    28381 aaggctgact ttgatgcaac tgtggcaatt cacccaactg catctgaaga atttgtaacc
    28441 atgcgttaat cgaaacaaaa gaagcttata taaatatgtc tgcttctttt ttaatgattt
    28501 tcgaatcaac aaaaaaatta tccaacttga ctagtcacga aaatcggctg ttacagtttt
    28561 tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata atagttacta
    28621 tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta tccctgctat
    28681 tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac ctgttccctt
    28741 cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga gagaggctgt
    28801 actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct ttgcaggagg
    28861 tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt tttatctcgt
    28921 ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta agatttttct
    28981 tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct tgcatttcct
    29041 agctggaatg gcatttgaaa aagctcttgt tgtgggggtt cttcccttta tcattccaga
    29101 ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac gccttaaaaa
    29161 tcaggcttac tttactaact aaaaaaggat accgagttat catgactcaa tatccttttt
    29221 ttattttgaa aacttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    29281 ctgctcaaaa cactgttttg aggttgtgga tgaaactgac gaagtcagta accatacata
    29341 cggcaaggca aagctgatgc ggtttgaaga gattttcgaa gagtattagt tgcctttaaa
    29401 ggcatccacc atcgtttgaa attcttcatt tgagagagta atccctttgc ccattttagt
    29461 atggtctgga ctccaagcac gaatatcaaa ctttgcagag gcaccattaa agctcacacg
    29521 gttaatttcc ttggtccaac ctttttcgtt ttcagaaaga gtcaacaagt gctcttcgat
    29581 ttcaaatgta aattctgcca ttttcttctc cttttttagt ttcattagtt tattcgtaaa
    29641 atcttgtaga ttttaggaaa attttatata atattgatat aaaagaaggg aggccaatat
    29701 gagacataaa ttccagcaag ttctaaataa aatacatgat tttttaaatg gatatgacca
    29761 acctgaccag actgaaacca actcccttac agccactatt gaagaggcta tccagaaaca
    29821 aaccgctgtt caccttatct tatctgagac aagctttaca ggtgacatca tcaaatatga
    29881 tcagcaaggc cagcaaatta tcgtgaaaaa tttttccaaa aatgtgagtc ggattatccg
    29941 tataagcgat attcaacgcc tgcgatttgt cccctcaact gtccaaacag cccaaaaaaa
    30001 tagatttaag aaagagtgag atgtagttgc ttcatcccac tcttttttct tagcgaattt
    30061 gttcaaaatg taaatgaact gcaatatgat ctccataacc acttctttcc aagtcacgtt
    30121 gtaaacgata ggaaatgtag tgttctgcaa tggtaatgta acctgcgccc aataaacgat
    30181 gttcaaccat agattgaatc atactgatag tcgcacgttc caccttggct tcttgtaaat
    30241 ccaaaactac cttcttagtg acttgagcaa gattttgacg caaatcatct gtcaaaacat
    30301 aaacagtttg ggctgccttc aagatggctt ggtaaatctt atctggatta aattcagcaa
    30361 tttcgccatt acgtttgatt acttgcatag gtttctcctt tattctttgt tttctttgat
    30421 ttctgccagc attttttctt cttctactgt cagttgataa tgttcaagta aatccggtct
    30481 gcgctcgtag gttttcttta aactctcgta caatcgccac tgacgaatct tttcatggtg
    30541 gccactcatc aatacatctg gcacgaccat gcctcgataa tcatagggac gtgtgtactg
    30601 aggatattct aaaagacctg aagaaaaact atcatcttgg tggctagact ccttgccaat
    30661 cacttctgga atcaggcgaa ctgtagcatc aatcatggtc atagctgcca attctccacc
    30721 agtgaggaca tagtcgccta gggaaatctc atctgttacc aaggtcttaa tgcgctcatc
    30781 ataaccctca tagtgcccac agataaagat tagctcttcc tcttgagcca aatcttcagc
    30841 ataagcctga tcaaactgct ttccagcagg atcgaggaga ataacgcgcg gatttttctt
    30901 ttcaatagca tcaaaggaat cgaaaatagg ttgtgctctg agcaacatgc cctgaccgcc
    30961 tccgtagggc tcatcatcta catgacgggc cttttcagca ttttctcgaa aattatgata
    31021 ctggatatcc aagagccctt tttctcgagc ctttccaacg attgagtgct ccagtggaga
    31081 aaacatctct ggaaagaggg ttaaaatatc aatcttcatc gtctaaccct tctaagattt
    31141 ccacatcgac ccgtttattt ggaatatcaa cattgagaac cactggtggg atataaggta
    31201 aaagcaaatc acgtttgcct tttcgtttga ccacccagac atcattagca cctggttgca
    31261 ggatttcctt gatggttcca accaagctat caccctcata gacttccaaa ccgataatct
    31321 cgtgatagta aaattcacca tcgtctaggt cattcaaatc ttcctcagcg accttgagac
    31381 tgtatccctt gtacttttcg atagtattga tatggtacat atctttgaat ttaataatgt
    31441 caaagttctt ctgtttacgg tggctagcga tggtcactgt ttggacaaac tgatcttttt
    31501 catcaaacaa agccagctca gctccttttt taaaccgttc ttctgcaaaa tccgtcacag
    31561 acaagactcg catctcaccc tgtaatccct gcgtattaac gattttccca acattaaagt
    31621 agttcatctt gtctcctgta atctcctttt ttccatctta ttctgacaat tctcgaataa
    31681 tagccgcaat tttttcctat tctgaccatt gtaaataatg gtgattcctt cctaaaatga
    31741 gtttagtatt ggaagtccaa tattctgatt ctctgtactc tttttctcta taagtctgac
    31801 aaaaaataaa tacagggaca tgagattcta tcgacaaatt ctcaaaatct tcctcagtaa
    31861 tctctccaga tatctgaaat tctggatctt gattttccaa ctctaagcct ttttcttgca
    31921 ttaattccca gattttttta ttcgtttcag gactaaatgt tgcttgagtt aagttcttaa
    31981 aataaagttc aggaccacac tcgtcaatca gcctcatctg ctcttccatt tctggataag
    32041 aattttctaa aaaatcagca aacatgactt tttagttgtc ggttcaattg ctactaaagt
    32101 ctgacgctta attggtttct cgagtaattt gcaagctaaa attccactcc aactatgtgc
    32161 acaaagtata tattcagaaa ttcctaattc ttcaagtact tcataaaccg catctgcaag
    32221 attatctaga ttttttccag cttggtcatg aatcggactc ctacctgtgt tcggaaaatc
    32281 aattgtcaaa taaccaattg taggaggagg tttttcaagt ataagtgaaa aattttcata
    32341 acttggtagc aaacctgctc cgtttagaca aactagcact ttcttttgct tttgataagc
    32401 aacagagaga ctaccaattt ctgtagatac ttcaaacctc ttcataaaga aatccactca
    32461 ttctatataa tgaattatta aaaatcctta tcttttattt tatcacgttc caaggatttt
    32521 ctcaagttgg aggaagggga caacatctct actttccctt caaaaatcct tccaaatcat
    32581 gtttatgttg gtaattaacg gctgcggttt tgtctttctc aaagacagtc ttggtaaggt
    32641 caatatgatt aatagctacg attgcgacgg tgtagtaaat gatatcagcc agttctctgg
    32701 caagttcctc gttcgaatcc tatcccttct tttcgaccag agcgcctatt caaaacctcg
    32761 gctacttctc cgacttcctc cactaacttc ataaagagac cttcatcagt ccgagactgc
    32821 tgttaatgtt cgagtaagta gtcttggaat tgcctaaacg ttcaatcttt tatagtatat
    32881 tgaaactaga atagtacacc tttacttcta aaacattgtt agaaatcgat ttgactgtcc
    32941 tgatcgattt gtcctgttat tatttcattt tactatatct tctattccac acaaaaaagc
    33001 gagacatccg tcccgccctt cttatttttc gtcaataacg attcttactt ttttgtattc
    33061 agttgggaca gagtagacaa tcgttcttat cgcagaaata gtgcgaccct tacgaccgat
    33121 tacacgaccc acatcgcttt gatcaagatt caaatgatat tccaaaaatt ctggtgtatc
    33181 ttcaatcttg atagttaagg catctggttg tgaaattaag ggtttcacaa tcgcaataat
    33241 gagattttca atcgtatcca tctgtcaacc tactttaaac ttattttgag aatttagaat
    33301 cgtggaattt tttcaatacg ccttcttttg aaaggatgtt acgtactgtg tctgaaggtt
    33361 gagctccatt agccaaccat gcaagaacgc gatcttcttt caaagttact tggttttcag
    33421 caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg tccgtcacgt ggtgaacgtg
    33481 aatctgctac gttgatacgg tagaaaggtt ttttcttaga acccatacga gtcaaacgga
    33541 ttttaactgc catttttaaa gtctcatttc tttaattttt tatttcggtg aaatagctga
    33601 gctatttagc acatgttcta ttatagcaga tttctggcat gtgtcaagaa aaaaacttga
    33661 cagactataa atttcttaaa gtatttagaa atttgttaga ataggaaata aatgtttgaa
    33721 agatgctatc cgtgaatact attttagaaa aattttataa agaacaccaa gtcaaaccct
    33781 tcatatcgcc tgaacgagag ttggatactt ggcttctaag tcccaagccc gttcccaagc
    33841 gaaatatgga cttattagca gatgattcac tagcaggaga tatcatttta ctatggagaa
    33901 tccagtttgg tacttttacc actgaaacat gattttaaaa actcccattc gaatatgatt
    33961 caaaattcgc ttagaatcaa tgttttccca ctttttcaaa aaataaattt tcatctaatt
    34021 taaataactt tcaattaagt gtgaattttg cttaaaatca ttaaaaaaca ccccatggtg
    34081 tgaaccatga agtgttgtaa atgctgtgtt gtagctagtt cttagcgttt agagaactgg
    34141 ctagctttac gagctttctt aagatctggt ttccaaaata ctttgagtac acttatggta
    34201 ttgatgcccc taaacatcta aaaactctgg tagaaaaagg gtatgctctt gtcgaaactt
    34261 cttttgactc acttgaccat ctaaatacta ccatgaaaaa gaatatcctg aagaagaagg
    34321 gagttactgg actttctaaa atgaaatctt gcgacctgga tcaagccctt catgagcatt
    34381 tttcagaaga agaattagct ggtcactttc atgtccttct atggactttt ttacaatggc
    34441 attgctatca cacccaatac ctatctaagc gcctggttcg taaactttat tgcagctctt
    34501 cctctaaatt tcctaattgt tgaaccaatt gcccgtttta tactaagttc ttttcagaaa
    34561 ccatttactg gggaagaagt tgaagaagtt gaagattttc aagatgatga tgaaatccca
    34621 actattatct aagccagttc tgtaaactac taatatttga aatccacttc cttttagggt
    34681 acaatggtta taaatgaatt tttgagagga tcagaatgaa aaaactagca acccttcttt
    34741 tactgtctac tgtagcccta gctgggtgta gcagcgtcca acgcagtctg cgtggtgatg
    34801 attatgttga ttccagtctt gctgctgaag aaagttccaa agtagctgcc caatctgcca
    34861 aggagttaaa cgatgcttta acaaacgaaa acgccaattt cccacaacta tctaaggaag
    34921 ttgctgaaga tgaagccgaa gtgattctcc acacaagcca aggtgatatt cgcattaaac
    34981 tcttccctaa actcgctcct ctagcggttg aaaatttcct cactcatgcc aaagaaggct
    35041 actataacgg tattaccttc caccgtgtca tcgatggctt tatggtccaa actggagatc
    35101 caaaagggga cggtacaggt ggtcagtcca tctggcatga caaggataag actaaagaca
    35161 aaggaactgg tttcaagaac gagattactc cttatttgta taacatccgc ggtgctcttg
    35221 ctatggctaa tactggtcaa ccaaacacca atggcagcca gttcttcatc aaccaaaact
    35281 ctacagatac ctcttctaaa ctccctacaa gcaagtatcc acagaaaatt atcgaagcct
    35341 acaaagaagg tggaaaccct agtctagatg gcaaacaccc agtctttggt caagtgattg
    35401 gcggtatgga tgttgtggat aagattgcta aagccgaaaa agatgaaaaa gacaagccaa
    35461 ctactgctat cacaatcgac agcatcgaag tggtgaaaga ctacgatttt aaatcttaaa
    35521 aaccaaaaaa aatacagtat ccacattcgg tactgtattt cttttactct cattcttaag
    35581 ttaaattatt aaaatcccat atttggtcta tccagccttc ataaaagtct agctcgtggc
    35641 agaccataag gatagatccc ctatattctt tgagagcgcg tttgagctca tcctttgcat
    35701 ccacatccaa atggttggtc ggctcgtcca gcactaaaac gttgttttca cgattcatca
    35761 agagacagaa acgaaccttg gcttgctctc cccctgataa tacttgaatc tggctttcaa
    35821 tatgtttggt tgtcaaacca caacgggcaa gggctgcacg gacttctgct tgattaaggg
    35881 caggaaaggc attccagaca gcttcaagag gagtttggcg attaccgcct tctacttcct
    35941 gttcaaaata accaagttct aaataatctc cacgctccac ttccccagcg attggcgaga
    36001 taatgcccaa gagactcttc aagagagttg tttttccaat accattagca ccaataatcg
    36061 caaccttttg attgcgttcg aaggtaagat ttaaaggctt agtaagagga cggtcgtaac
    36121 caatttgcaa gttcttggct tggaagataa agcgccctgg tgtacgagct ggtttgaaat
    36181 caaaggatgg ttttggtttc tcactttgga gttcgataat atccatctta tccaatttct
    36241 tttgacgaga catagccata ttacgagttg caacacgggc tttattacga gccacaaagt
    36301 ccttgaggtc tgcaatctct ttctgctggc gttcgtaggc tgcctctagc tgagatttct
    36361 tcatagcata aacttcttgg aactggtagt agtcaccaga gtaacgcgtc agctgttgat
    36421 tttccacatg atagacaata ttaataacgt cattgaggaa tggaatatcg tgcgaaatga
    36481 gaacaaaggc attctcatag ttttggagat agcgcttgag ccaatcaata tgctcagcat
    36541 ccaagtagtt ggtcggctcg tccaacagca agatatcagg cttttcaagg agaagttttg
    36601 ccaaaagcac cttggttctt tgcccacctg acaaagaagt tacatccgta tccatgccaa
    36661 agtccataac accaagagca cgcgctactt cgtcaatctt agcatccaag gtatagaaat
    36721 cacgactctc cagacggtct tgaagttctc ctacttcttc catgagagca tcaacatccg
    36781 cgccgtcttc agccattttc atatagaggt cattgatacg agcttcagct ttgaaaagct
    36841 catcaaaagc cgtacggaga acatcacgca ccgactgtct ttcagcaagg acagagtgct
    36901 gatccaagta accagccgtc acatatttgg accactcaac ctttccttca tctggcagca
    36961 ttttaccagt cacgatactc ataaaggttg attttccttc accattggca ccgaccaggc
    37021 cgatatgttc tcccttgagg agacggaagg acacatcttc aaaaattgca cggtcaccaa
    37081 aaccgtgact cagattttta acttctaaaa tactcatttt aattccttat cttgttttta
    37141 tgtaatcgtt tataaaggag ccaagccaga tagccaccca aagtgttggt ccacaaatca
    37201 tcaatctcaa agacgcgatt gaaatcaaag aaaaagtcta agattaattg cgtacactcg
    37261 attccaagac tcacaagaaa actaaaaaga aggacctttt ttgttttccg caaatttgga
    37321 aatagataaa ggagttggaa aatcagagga aaaaacaaga agacattgag gatattttgt
    37381 aaaaaaatcc aacataattg tccaatgtca ctcacttcgc ccagtttcca gagagaattg
    37441 aaaggagtca aaagaaaaac caggcgtcca agatgctgaa tacctggagt tcccactccc
    37501 acggtagatt gttcttgagg agtaaagcaa aaacagacaa tgcaaatgct atagaaaatg
    37561 actccccaga ccaaaatatg attataagtc ttcttcatca ttaaggattt accgctgcga
    37621 ctgccttctg gcggtcacgt ttcattgtgt tagagcgcaa ttgtccacaa gctgcgtcaa
    37681 tatctgtacc atgctcttga cgaaccacac agttgacccc ttttttctta agcgtatcat
    37741 agaaagccaa cacgcgctct ttgggactac ggctatattg gtcatgctca ctaactgggt
    37801 tataaggaat caagtttaca taagacaatt tcttgatgtt cttgagcaat tcagtcaatt
    37861 ccaaggcttg ttctacaccg tcgttgactt cattaagcat gatatattca aaggttacac
    37921 cacggtttgt tgtctcaatg tagtattcaa tagcagcaaa gagtttttca atcggaaagg
    37981 cacggttaat cttcatgata cttgaacgaa gttcattgtt aggtgcgtga agagacacgg
    38041 caagattgac ctgaacccct tcatcagcaa agtcacgaat tttatgagcc aaacctgagg
    38101 ttgaaaccgt gatgtgacga gcaccgatag ccattccttt atcatcattg atagtacgaa
    38161 agaaattcaa gacattgttg taattatcaa agggctcacc gattcccatg acaacgatat
    38221 ggctgatgcg ttcatcctga ccacgctcat caaagtattt ctgaaccagc atgatttgcg
    38281 ctacgatttc accgttattg aggtcacgtt gcttcttaat caaaccagag gcacagaagg
    38341 tacaaccgat attacagccg acctgagtgg tcacacagac agataaacca tagtgttgac
    38401 gcatgagtac agtctcaatt aacataccgt cgggcaattc aaagagatat ttgactgtac
    38461 catcagcaga ctcttgcaca atacgttgtt tcaagggatt gaccacaaac tggtcattga
    38521 gcttagcaat caaatccttg gaaaggttgg tcatttcttc aaatgactgc acacgtttac
    38581 ggtagagcca ttcccagatt tgatctgcac ggaatttctt ttctccctgc tccaataccc
    38641 attcctgcat ggtttgatgt accaaactat gaattgaggg tttcatttct tctccttatt
    38701 ctctactcac ttctgacgaa tgacaaaatg acgttgtccc ttgtcctctt tctgagaatg
    38761 ctggtctttc tgacgacgtc tatttttctt atctgcattc gactttcgtt tagtttgagt
    38821 cggtttcttt ccttttctag aaggtgtttc ttcttccgtc ttacgcattt tcttgtcaaa
    38881 tgatgctcgc ttaggggctt cattttctaa gacaaaatag gcacaaccat aactacaata
    38941 ctctaaaagg tagtcttgta aacgactgat tttttcaagt ttttcttctg ttcggtcatc
    39001 cttgtaaaaa cctcgtaggc gaagctgttc gttgctccag tcccccacga tataatcaaa
    39061 cttggttaag acttctgaaa aacgctgatt aaaagtcgtc acatcaaagg catccttgat
    39121 attttcaacc aaggaaaaag ctatcccttc cgtttcgacc ttgtccccgt gtaaatggaa
    39181 ctccggacca ggaaacttgt tatagttgta taattcaggt gcaatttctt ttcgcataga
    39241 tatccttttt ccacgattac ttaatacttt attctaccat aatttctagc agttagcacg
    39301 tttctcataa aaatgaaaaa agtctgacga ttttgtcaga ccagaatctt ataacctaaa
    39361 aagagaagaa caattcttcc ctccaactat cattatttag cagctgcgta caattcatct
    39421 actttattcc agttgattac tgaaaagaaa gctttgatgt agtcaggacg cacgttgcgg
    39481 tatttcacgt agtaagcatg ttcccaaacg tccaagccca agattggttt tttaccttct
    39541 gagattggtg tgtcttggtt tgctgttgaa gtcacttcaa gtttcccttc tttgttgaca
    39601 accaaccatg cccaacctga accaaaacga gttgttgctg ctgcagtgaa ggctgcttgg
    39661 aattcttcaa atgaaccaaa tgttgcatcg attgctgctg ccagttctgc tgaaggagct
    39721 gttttctcgg gagtcatcaa ttcccagaaa agagcgtggt tcaagtgtcc gccaccattg
    39781 ttgataagtg cttgacggat atcagctggg atagattcta catcagcaag caaggcttca
    39841 aggtcttcac cgatttcagg gtgtttttct aaagctgcat tggcattgtt gacataagtt
    39901 tgatggtgtt tgtcatggtg taaatgcatt gtttccgcat cgatgtatgg ttccaaagcg
    39961 tcgtatgcat atggaagttc tggtaagata atagccatct gtaatacctc tttttctttc
    40021 tatatgaaaa tgataacgca aacattcact tttttcaagt tttttgctta tagataagga
    40081 aatcactgac atactttcta ataaaataag caaatcagca agaaacccac gacaagataa
    40141 tcctgacgcg ggttgtagtt tcaacaaatg tcaattgacc tgactagcaa tctgtaagag
    40201 tgccttttca aaaaggaaac ctttttcata aagacctgtc ttaatctgat agtctgtctc
    40261 aatcaaatag gaaatagctt gcttcagaaa gctcaaagaa agtcctctcg aatctcttaa
    40321 tgcaaacttg atttgataag gatttgggtt acgtcccaga taactaccta aactacttgc
    40381 aatctgcgat tctgtttggc cagactccgc caaaatcttc acctgagtaa aagtccgaaa
    40441 ttgtcccagc atgactgcaa tcagtttgat ttcatcttcc ccttgcaagg tcaagtctct
    40501 caccaaatcg cgcgcctgat ccatcttttt agtcagaata aactgagtta aatcaaaaat
    40561 attgtcctgc aaggtcttgg gaattgcgtt aacaatatcc tcttcctcga taacagaatc
    40621 cgccttatag gactgtaaaa agagaagatt tttctggatt tcgctaaatt gaaaccccga
    40681 cttgatgagg agattttcaa aagaatgatt ggtaaactgc agaccttgtt tctgactcca
    40741 cttttggaaa tactggcgca attcttgttc ttttacttct actgcatcga agaccttggc
    40801 atcacgctta agtaatttga ctaaccgtct tttgctatcc agctttcctt ctgcaaagat
    40861 tatcaacttg gttgttggag aaggattgtc aaggtattcc tcaaatgact taagctcatc
    40921 atctgtcaaa aagcgtttct tagcagtcgt gatatccata aaataatcta atatcactat
    40981 tttctcatcc gcaaagaaag gaaggctgac caactccagt tccacatcct tgtaaactac
    41041 ttctttcata tcaaagtagg caaagttgag gtcagcagaa tcatacccaa tctgtttcaa
    41101 catttgactc ttcatcactt caaactgacc ctgatctgtc cctgtaaata ggctcaggct
    41161 cggtaaattt gataaagtca acttctgact ttcttcaatg gctagcatcg actctccttt
    41221 cttcagattt ttcgatttaa tttagtcaat atagcgcaat ttcccacgga aatcttctaa
    41281 gctctcgtag cctttttcca ccatgattgc tttcagttca ttggtaatgc ggtcaaaagc
    41341 actgacgcct tctttgtgaa gggtcgttcc cacctgcacc atacttgctc cacagaggat
    41401 gtgttcaaag gcatctcgac cagtcagaac gccacctgtt ccgataattt ggatttgagg
    41461 atttaaacgt tgataaaagg cgtgaacatt ggctagagca gtcggtttga tgtattctcc
    41521 accaattcca ccaaaaccat tcttaggccg aataacgaca gattcgtctt ctatatagag
    41581 gccgtttccg atagagttaa cgcagttgac aaacttgagc ggatatttgt tgaaaatagc
    41641 tgccgcttgg tcaaagtgaa caatatcaaa ataaggtggc aatttaattc caagaggttt
    41701 ggtgaagtaa gcaaacactt ctgccaaaat ccggtctgtt gtctcaaaat cataggcaat
    41761 ctgaggttta cctggaacat ttggacagga aagatttagc tcagtcagac cacgaaaatc
    41821 actctcttgg acttttttca aaatagtatg ggtttcctct ggagacatgc cgaccagaga
    41881 taagaagaaa gttcggttcg actctttttc ctgcaaatct aaaagataat ccaaataata
    41941 gtctaagcca ttatttggca agcccataga gttgatggaa ccaagtggaa catcttggta
    42001 gcgtggctca ggattcccct gacggaagtc caaggtcgct gtcttagtaa caaaggttcc
    42061 tgccgctgag tttttgacct cttctaactc ctctatcgtc atacaagcca cacctgctgc
    42121 attcatcaag caattgtcaa actcaaaacc agcaatttgt gttttcgttg ataccatgat
    42181 tctaatcctc cagatttctt ttattgctaa tattatacca taattttaat tctaggttta
    42241 ctagattctg tggttctatc tatttattcg gaaaagaaag tctagtacag aagtcatgct
    42301 atggaaacag ctagtgtatt ggaagtttga acaaggcttg ggtaacagac ttttgaatga
    42361 agtccaagca acaaggagaa atctcaacca tgagtccatt ccatgactct gttgctctag
    42421 aaaaccttgc aatagtcaag tgataacgaa taaaactttg gattgaaata tccccatgat
    42481 tatctattac gaggagaaat ctcaaccttt atcattttta gagaaatata gtaaaatgaa
    42541 acaagaacag gagaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt
    42601 tgaggtgtac tattctagtt tcaatctact atacatg
//
LOCUS       DBEJNA010000017        40401 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEJNA010000017 DBEJNA010000000
VERSION     DBEJNA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.17"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            5..75
                     /locus_tag="ACL3JB_001014"
     tRNA            5..75
                     /locus_tag="ACL3JB_001014"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="ACL3JB_001015"
     tRNA            110..183
                     /locus_tag="ACL3JB_001015"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="ACL3JB_001016"
     tRNA            266..355
                     /locus_tag="ACL3JB_001016"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="ACL3JB_001017"
     tRNA            366..439
                     /locus_tag="ACL3JB_001017"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="ACL3JB_001018"
     tRNA            443..515
                     /locus_tag="ACL3JB_001018"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="ACL3JB_001019"
     tRNA            528..608
                     /locus_tag="ACL3JB_001019"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="ACL3JB_001020"
     tRNA            613..683
                     /locus_tag="ACL3JB_001020"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="ACL3JB_001021"
     tRNA            698..770
                     /locus_tag="ACL3JB_001021"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="ACL3JB_001022"
     tRNA            781..852
                     /locus_tag="ACL3JB_001022"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="ACL3JB_001023"
     tRNA            862..945
                     /locus_tag="ACL3JB_001023"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="ACL3JB_001024"
     CDS             1052..2329
                     /locus_tag="ACL3JB_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0685767.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDETDFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /gene="thrC"
                     /locus_tag="ACL3JB_001025"
     CDS             2405..3889
                     /gene="thrC"
                     /locus_tag="ACL3JB_001025"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0685768.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAKLMNALNSQGQYELTNFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQSATGDVTKTVIASTASPYKFPVVAVETVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMKAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="ACL3JB_001026"
     CDS             3950..5230
                     /locus_tag="ACL3JB_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0685769.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="ACL3JB_001027"
     CDS             5234..5854
                     /locus_tag="ACL3JB_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0685770.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLSQVRAQSLTEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7162
                     /locus_tag="ACL3JB_001028"
     CDS             6020..7162
                     /locus_tag="ACL3JB_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0685771.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTS
                     SEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7590..8013
                     /locus_tag="ACL3JB_001029"
                     /pseudo
     CDS             7590..8013
                     /locus_tag="ACL3JB_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            8024..8383
                     /locus_tag="ACL3JB_001030"
     CDS             8024..8383
                     /locus_tag="ACL3JB_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR0685772.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKDLLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8490..9133
                     /gene="pcp"
                     /locus_tag="ACL3JB_001031"
                     /pseudo
     CDS             8490..9133
                     /gene="pcp"
                     /locus_tag="ACL3JB_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9161..10018)
                     /locus_tag="ACL3JB_001032"
     CDS             complement(9161..10018)
                     /locus_tag="ACL3JB_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0685773.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10148..11290
                     /gene="tgt"
                     /locus_tag="ACL3JB_001033"
     CDS             10148..11290
                     /gene="tgt"
                     /locus_tag="ACL3JB_001033"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0685774.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11388..13205
                     /locus_tag="ACL3JB_001034"
     CDS             11388..13205
                     /locus_tag="ACL3JB_001034"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0685775.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPSYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13358..14509
                     /gene="nagA"
                     /locus_tag="ACL3JB_001035"
     CDS             13358..14509
                     /gene="nagA"
                     /locus_tag="ACL3JB_001035"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0685776.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14672..15730
                     /locus_tag="ACL3JB_001036"
     CDS             14672..15730
                     /locus_tag="ACL3JB_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0685777.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15881..16246
                     /locus_tag="ACL3JB_001037"
     CDS             15881..16246
                     /locus_tag="ACL3JB_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0685778.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16322..17263
                     /gene="comGA"
                     /locus_tag="ACL3JB_001038"
     CDS             16322..17263
                     /gene="comGA"
                     /locus_tag="ACL3JB_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0685779.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17211..18227
                     /gene="comGB"
                     /locus_tag="ACL3JB_001039"
     CDS             17211..18227
                     /gene="comGB"
                     /locus_tag="ACL3JB_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0685780.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18229..18555
                     /gene="comGC"
                     /locus_tag="ACL3JB_001040"
     CDS             18229..18555
                     /gene="comGC"
                     /locus_tag="ACL3JB_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR0685781.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18548..18952
                     /gene="comGD"
                     /locus_tag="ACL3JB_001041"
     CDS             18548..18952
                     /gene="comGD"
                     /locus_tag="ACL3JB_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0685782.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18915..19217
                     /gene="comGE"
                     /locus_tag="ACL3JB_001042"
     CDS             18915..19217
                     /gene="comGE"
                     /locus_tag="ACL3JB_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0685783.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEL"
     gene            19180..19641
                     /gene="comGF"
                     /locus_tag="ACL3JB_001043"
     CDS             19180..19641
                     /gene="comGF"
                     /locus_tag="ACL3JB_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0685784.1"
                     /translation="MVQNSCWQSKSYKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFHFQFQKGLEREFIYRVEKEES"
     gene            19619..20032
                     /gene="comGG"
                     /locus_tag="ACL3JB_001044"
     CDS             19619..20032
                     /gene="comGG"
                     /locus_tag="ACL3JB_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0685785.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20169..20756
                     /locus_tag="ACL3JB_001045"
                     /pseudo
     CDS             20169..20756
                     /locus_tag="ACL3JB_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20817..21770
                     /locus_tag="ACL3JB_001046"
     CDS             20817..21770
                     /locus_tag="ACL3JB_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0685786.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21821..23011
                     /locus_tag="ACL3JB_001047"
     CDS             21821..23011
                     /locus_tag="ACL3JB_001047"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0685787.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23012..23143
                     /locus_tag="ACL3JB_001048"
     CDS             23012..23143
                     /locus_tag="ACL3JB_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685788.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            23160..23531
                     /gene="rnpA"
                     /locus_tag="ACL3JB_001049"
     CDS             23160..23531
                     /gene="rnpA"
                     /locus_tag="ACL3JB_001049"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0685789.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23506..24330
                     /locus_tag="ACL3JB_001050"
     CDS             23506..24330
                     /locus_tag="ACL3JB_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0685790.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24349..25335
                     /gene="jag"
                     /locus_tag="ACL3JB_001051"
     CDS             24349..25335
                     /gene="jag"
                     /locus_tag="ACL3JB_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0685791.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25386..26009
                     /locus_tag="ACL3JB_001052"
     CDS             25386..26009
                     /locus_tag="ACL3JB_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0685792.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEARKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26140..27597
                     /locus_tag="ACL3JB_001053"
     CDS             26140..27597
                     /locus_tag="ACL3JB_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0685793.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27620..27901
                     /locus_tag="ACL3JB_001054"
     CDS             27620..27901
                     /locus_tag="ACL3JB_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0685794.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27978..28463
                     /locus_tag="ACL3JB_001055"
     CDS             27978..28463
                     /locus_tag="ACL3JB_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0685795.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28480..29145
                     /locus_tag="ACL3JB_001056"
     CDS             28480..29145
                     /locus_tag="ACL3JB_001056"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0685796.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29149..30012
                     /locus_tag="ACL3JB_001057"
     CDS             29149..30012
                     /locus_tag="ACL3JB_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0685797.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            30014..30718
                     /locus_tag="ACL3JB_001058"
     CDS             30014..30718
                     /locus_tag="ACL3JB_001058"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0685798.1"
                     /translation="MNQVINAMRKRVCAANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30895..32568
                     /locus_tag="ACL3JB_001059"
     CDS             30895..32568
                     /locus_tag="ACL3JB_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0685799.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QNFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32680..33771
                     /gene="ulaG"
                     /locus_tag="ACL3JB_001060"
     CDS             32680..33771
                     /gene="ulaG"
                     /locus_tag="ACL3JB_001060"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0685800.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33885..35861
                     /gene="tkt"
                     /locus_tag="ACL3JB_001061"
     CDS             33885..35861
                     /gene="tkt"
                     /locus_tag="ACL3JB_001061"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0685801.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAEYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVISMPSTDVFDKQNAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35978..36277
                     /gene="yajC"
                     /locus_tag="ACL3JB_001062"
     CDS             35978..36277
                     /gene="yajC"
                     /locus_tag="ACL3JB_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0685802.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36324..36752
                     /locus_tag="ACL3JB_001063"
     CDS             36324..36752
                     /locus_tag="ACL3JB_001063"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0685803.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36754..37164
                     /locus_tag="ACL3JB_001064"
     CDS             36754..37164
                     /locus_tag="ACL3JB_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0685804.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37464..40115
                     /gene="adhE"
                     /locus_tag="ACL3JB_001065"
                     /gene_synonym="adhC"
     CDS             37464..40115
                     /gene="adhE"
                     /locus_tag="ACL3JB_001065"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0685805.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKTRQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARILGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12245 a         7244 c         9102 g        11810 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttatgaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgaattttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaaac
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgtccgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattattta cccccaagag aaggattttg aaactcatcg
     1981 tagttaccag taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactacgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggata cttatccaaa
     2521 ggtagatttg aactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagt tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatctt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaaggg tggtgtcagc aaggtacaag agttgcaaat
     2941 gaccactcag aatggtgaca atactcatgt tatcgctata gatggtaact ttgacgatgc
     3001 gcaaaccaac gtgaagcaca tgtttaacga cgtggctctt cgtgaaagat tagcggccaa
     3061 caagttgcaa ttttcatctg ctaactctat gaacattggt cgtctggtac cacagattgt
     3121 ttattatgtt tatgcctacg ctcagttggt caagactggt gagattgtgg ctggcgataa
     3181 ggtcaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaatcggt ctcccagttg gtaaattgat ctgtgcttca aatgacaaca atgttttgac
     3301 agacttcttc aagacacgtg tttacgacaa gaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgtttg attttccatc ttttggggaa
     3421 tgatgcggtt aagacggcta aactcatgaa tgctttgaat agccaaggtc aatatgagtt
     3481 gactaatttt gatgcagaga ttttggacct ctttgcagct gaatatgcga ctgaggaaga
     3541 aactgcggca gaaatcaagc gtgtttatga gtcagattct tatatcgagg atcctcatac
     3601 agcggttgcc tcagcagtgt atagaaaata ccaatcggcc actggagatg taactaagac
     3661 agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag aaactgtaac
     3721 tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga aatagctcca attcgtcaca agacaacagt
     3841 ggcagctgct gacatgaaag cagcggttga ggcttattta ggactttaag acagagggag
     3901 caaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagtct
     4381 gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttctgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agccaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gttatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttggaacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc gcattggaac
     5101 aggatatctg ctggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaagatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaagt caggtgcgtg cccagagtct
     5461 gactgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaacct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatcatagac aggtactcat
     6001 ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgatactttg agcaccattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacag aagttgaaat ccaaacacct caagcagact ctagtgaaga
     6361 agtgacaact gcgacagcag atttgaccac taatcaagtg accgttgatg atcaaactgt
     6421 tcaggttgca gacctttctc aaccaattgc agaagctcca aaagaagtag catcaagttc
     6481 agaagttaca aagacagtga ttgcttctga agaagtggca ccatctacgg gcacttctgt
     6541 cccagaggag caaacggccg aaacaactcg cccagttgaa gaagcaactc ctcaggaaac
     6601 gactccagct gagaagcagg aaacacaagc aagccctcaa gctgcatcag cagtggaagt
     6661 aactacaaca agttcagaag caaaagaagt agcatcatca aatggagcta cagcagcagt
     6721 ttctacttat caaccagaag agacgaaaac aatttcaaca acttacgagg ctccagctgc
     6781 gcccgattat gctggactgg cagtagcgaa atctgaaaat gcaggtcttc aaccacaaac
     6841 agctgccttt aaagaagaaa ttgctaactt gtttggcatt acatccttta gtggttatcg
     6901 tccaggagac agtggagatc acggaaaagg tttggctatc gactttatgg taccagaaag
     6961 ttcagaatta ggggataaga ttgcggaata tgctattcaa aacatggcca gccgtggcat
     7021 tagttacatc atctggaaac aacgtttcta tgctccattc gatagcaaat atgggccagc
     7081 taacacttgg aacccaatgc cagaccgtgg tagtgtgaca gaaaatcact atgaccacgt
     7141 tcacgtttca atgaatggat aaacccgact tggtaacatc attttgacga atgagatcta
     7201 gctttcgtga taggaagcga ttctcgttcg ttttttcttt gtcatactct tcgaaaatct
     7261 cttcaaacaa cgtcagtttt atctgaaacc tcaaagctgt gctttgagca acctgcgact
     7321 agcttcctag tttgcttttt gattttcatt gagtatcaat ttgaatggaa aatggaaagt
     7381 tatcatcttg taatgagtta agcaacattc ttgcaatcta ttttatagta gattgaaact
     7441 agaatagtac acaactgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
     7501 tttgtcctgc tcttatttca tttcactata ctttatatta taattgactg gtcaaatatt
     7561 gataaatcaa taaaaagaga ggggaagaaa tgctagagat tcaagattta ctgtatcaac
     7621 tccgcttgtc tgagcaagtg agtacgcaat tgtttgaaaa agcttgggat tagtttgaca
     7681 cggtatcaga ttttactgtt tttgctggag cattctcttt gtaaccaaat ggcggttcag
     7741 gagcgtttga aaattgatca ggctgctttg acacggcatt tcaagatttt ggaaacggaa
     7801 ggtttggtgg agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg
     7861 aagtatgcca aggagcagtt agtggtgaat ccccctctgc aacatatcaa ggttaaggaa
     7921 gagatggaaa gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa
     7981 ttggttttgg gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac
     8041 aacgatcgtt gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc
     8101 agatgcgact agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag
     8161 ttcattgttc aaaaatcaag gaatttataa ggatctgcta ggagtctttc tcttgtatgg
     8221 catttatttc tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc
     8281 tgcgacttac ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc
     8341 tattttggcc ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc
     8401 gctaatcctt ttcaatccag aataagggaa atatgttata cttgttttta agaaaaaagt
     8461 ctcattgaat tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct
     8521 ttggagggga aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc
     8581 atggtgctga ggtccgttgg ctagaggtgc cgacagttct tcacaaatct gctcaagtat
     8641 tggaagaaga gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg
     8701 gaagaactag tttgacacct gaacgagtgg ccattaatca agacgatgca cgtacttctg
     8761 ataacgaaga taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact
     8821 ttagtagttt gccgattaaa gcgatggttc aagctataaa aaagaaggat tgccggcctc
     8881 tgtttccaat acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt
     8941 ggtagaaaag aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga
     9001 acaggtggtg aacagaccgc ctattccagc tatgagttta gtggatattc ggcgagggat
     9061 agaagcagca atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg
     9121 agaaactcat tgatagaaaa aagcttgagg ggaaaaacct tcaagctttt ggacgttttc
     9181 gagccaatac tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa
     9241 aactagcaat gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta
     9301 ggacaaagtg ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc
     9361 ttggtgggac ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg
     9421 cataatactg tggaatatag aggatattcc ctacaatgat caagatgaga cttgcaagaa
     9481 agtagagtcc aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg
     9541 gaaactcagg atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt
     9601 aaatcccaag taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg
     9661 tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg
     9721 gctccgtttt agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa
     9781 tagtcccgat aaaggagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta
     9841 tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac
     9901 tagataagat gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag
     9961 cctgaaaatg ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc
    10021 tcttattata ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa
    10081 tcatacagtg tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag
    10141 gtaaaaaatg tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg
    10201 agctcgtcta ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc
    10261 agttgggaca caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc
    10321 gggaattatc ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc
    10381 acgcgctggt ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg
    10441 tggttttcag gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt
    10501 taaaaatcat ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca
    10561 gaataatctg ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc
    10621 ttatgactac gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa
    10681 ggctcaccgt cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga
    10741 agaccttcgc cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat
    10801 cggtggtttg gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac
    10861 tcaactgcta cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt
    10921 gatcgatggg gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc
    10981 tcgtaacggg acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc
    11041 tgaggacttt acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg
    11101 cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta
    11161 ccacaatctt tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga
    11221 caatctcttg gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg
    11281 taatttctaa aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc
    11341 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    11401 ggttttcctt gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga
    11461 cgatctttcc tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga
    11521 ttacagctct actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt
    11581 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    11641 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg
    11701 tcttaggctt tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt
    11761 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    11821 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    11881 ggatggtctt tctcttatct gctgctgcct tcttgatcag tttcttctcc atgtttattg
    11941 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    12001 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    12061 tcaagcagtt ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct
    12121 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    12181 tcggcttctt gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    12241 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    12301 atgcggttta tcttttccat tggccttcct atatcatttt ctcacagttg acatcaaatc
    12361 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg
    12421 tattggaacc ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc
    12481 cttatattca cgcaattctt gcagcaggta caggaatctt gaccttcatt gtctgcatgg
    12541 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtt aatggcttga
    12601 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    12661 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    12721 cagcactaca gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    12781 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    12841 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    12901 aaaatcttcc taagggacac cgtatgattt tggtgactcc ttatgaggga gataagacaa
    12961 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    13021 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    13081 caggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    13141 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    13201 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    13261 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    13321 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    13381 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    13441 gtttgggaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    13501 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    13561 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    13621 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    13681 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    13741 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    13801 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    13861 ccttgcacca gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt
    13921 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    13981 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    14041 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    14101 tcaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    14161 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    14221 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    14281 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    14341 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    14401 cgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    14461 ggaattggta gcaacctacc tagatggtgt gaaacgttat caagcataag agagaaggca
    14521 gaagttagag actagcttct gcttttttat acagggtact ttactggtaa ataaaaagtt
    14581 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa
    14641 tattacaaat aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg
    14701 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt
    14761 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    14821 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    14881 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    14941 tggtaaatgc tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg
    15001 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    15061 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    15121 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    15181 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    15241 ttcaccagct aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc
    15301 attcggtgcg actcataagg ttaattcttc agaccctaaa aaagccatta aagaaattta
    15361 tgatttgaca gatggtcgtg gtgtggatgt cgctatcgaa gctgtaggga ttcctgaaac
    15421 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    15481 tggtaaacca gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac
    15541 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    15601 tgaaccggaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga
    15661 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    15721 agaagcctaa gtagtaaaaa tatttttgta cataagcaaa tagaaattca gtcatccatc
    15781 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    15841 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    15901 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    15961 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    16021 ggaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    16081 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    16141 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    16201 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    16261 tttggagttg ctttttttat ttttctaact ctttgcgaat agtataggtg aggaggtaag
    16321 tatggttcaa gaaattgcac aagaaatcat tcgttcagct cggaaaaaag ggacgcagga
    16381 tatttatttt gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg
    16441 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    16501 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    16561 ctatgaccag aagatagcgt ctctacgttt atctactgta ggcgattatc gggggcatga
    16621 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    16681 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt
    16741 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    16801 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    16861 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    16921 agatctcttg attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc
    16981 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta
    17041 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    17101 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaaaca gagattatca
    17161 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    17221 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    17281 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag
    17341 ataggagttc cttgttggac aagcagtgtg tgacccagat gcgtacaggc ttgtctcagg
    17401 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt
    17461 tatctctagc tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc
    17521 tagacaatct ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt
    17581 tgctgggttt tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg
    17641 atagtagcaa tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg
    17701 tagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    17761 tgagtgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact
    17821 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc
    17881 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    17941 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    18001 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    18061 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca
    18121 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    18181 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    18241 atgacattct tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttagtagtc
    18301 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    18361 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    18421 tatagcttag aaaagaatga agatgctagc ctaagaaagt tacaagcaga tgggcgcatc
    18481 acggaagaac aggttaaagc ttataatgaa tactatacta aaaatggagg ggcaaatcgt
    18541 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gacttgtgag
    18601 tatccttgcc ttgggcttat ccggctctgt ccagtccact tttgcagcag tagaggagca
    18661 gattttcttt atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    18721 tcagcaaaag actagtctaa atttagatgg gcagacgctt agcaatggca gtcaaaagtt
    18781 gacagttcct aaaggaattc aggcaccatc aggccaaagt attacatttg accgagctgg
    18841 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    18901 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    18961 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    19021 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    19081 gggtagctaa gatggccttg cagacaggtc aaaatcaggt aaacataaac ggagttgaga
    19141 ttcaggtgtt ttctagcgaa aagggattgg aggtctacca tggttcagaa cagttgttgg
    19201 caatcaaaga gctataaggt caaggctttt accttgttag aatccctgct tgccctgctt
    19261 gtcatcagtg ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19321 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggta
    19381 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19441 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    19501 ggacgggggt atcagcctat ggtttatggc ctcaaatcag ctcagattac agaagacaat
    19561 caactggttc gctttcattt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19621 gtggaaaaag aagaaagtta aggcaggtgt tctcctctat gcagtcacca tggcagctat
    19681 ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc
    19741 tttaaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    19801 gcaagaaagt ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac
    19861 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    19921 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    19981 agtggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    20041 actataatgc gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg
    20101 atgttaagct ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa
    20161 ctaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgactcc cctaaaaata
    20221 tcttcctcgc aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca
    20281 aagtaatttt agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg
    20341 ctaagtcagt tactcttgta gacatttctg agaaaatgtt ggagtaagct cgtttgaaag
    20401 cggagcagca agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct
    20461 tggagaaaga gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg
    20521 atgcggatct ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg
    20581 attttaccaa gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc
    20641 taattgagca tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacctgt
    20701 ttcaagggaa tcactcagaa ttctttttaa cagtatccca aaaatcactc gcctagtcag
    20761 ggagtgattt ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg
    20821 attttgaaaa aattgaacaa gcttatatct atttactaga gaatgtccaa gtcatccaaa
    20881 gtgatttggc gaccaacttt tatgacgcct tggtggagca aaatagcatc tatctggatg
    20941 gtgaaactga gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac
    21001 gcaaagaaga atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac
    21061 ccttgcaggc caatcaccag tttacaccgg atgctattgc tttgcttttg gtgtttattg
    21121 tggaagagtt gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa
    21181 ttctaggcgc tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaag
    21241 tggatgattt gctgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg
    21301 gctttgtcca aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca
    21361 gtgacttgcc tgtcggctat tatcctgatg acgccgttgc gtcgcgccat caagttgctt
    21421 ctagccaaga acatacttac gcccatcact tgctcatgga acaagggctt aagtacctca
    21481 agtcagacgg atacgctatt tttctagctc cgagtgattt gttgaccagt cctcaaagtg
    21541 atttgttaaa agaatggctg aaagaagagg cgagtctggt tgctatgatt agtctgcctg
    21601 aaaatctctt tgctaatgct aaacaatcta agactatttt tatcctacag aagaaaagtg
    21661 aaatagcagt ggagcctttt gtttatccac ttgctagctt gcaagatgca agtgttttaa
    21721 tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt
    21781 gttataatag ttgaaaacgc ttaaaaaggg gtatcatatt atgacaaaaa caattgcaat
    21841 caatgcagga agttcaagtt tgaaatggca attatactta atgccagaag aaaaagtatt
    21901 ggcgaaaggt ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga
    21961 cggccgttct gaacaacaaa ttttggatat tgaaaatcat atacaagccg ttaaaatttt
    22021 attggatgac ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg
    22081 acatcgtgtt gttgctggtg gagaatattt caaagaatca acagttgttg agggagatgt
    22141 tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc
    22201 aggtgttcgt gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac
    22261 ttccttccac acaagtatgc cagagaaagc ttatcgttac cctctaccaa caaaatatta
    22321 cacagaaaac aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg
    22381 agaagctgca aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat
    22441 tggtaacgga ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg
    22501 gttcactcct cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat
    22561 cattccttat ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt
    22621 tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat
    22681 agaagcagct gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga
    22741 ccgtatccaa aaatatatcg gtcagtacct tgcagtgcta aatggagcag atgccattgt
    22801 tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat
    22861 ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat
    22921 ctcaacagag gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat
    22981 tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg
    23041 agttgggaaa gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat
    23101 gattggcttt tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt
    23161 tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga
    23221 caagttttgc taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc
    23281 gagtaggtct atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc
    23341 gacggattcg gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg
    23401 ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac
    23461 tccatgtatt aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta
    23521 aagttgacta gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg
    23581 gtaactagcg atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt
    23641 gcggaaatca ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt
    23701 acggtcttga ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg
    23761 aaaatgcagg aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat
    23821 atggaaagca gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc
    23881 agacagtcag attctctttg gccgattttg attcagatgc cggttatttt ggccttgttc
    23941 caagccctat caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt
    24001 agtgtggata caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact
    24061 tggttgtcca acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg
    24121 attccagtct tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg
    24181 acagtgtcta atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt
    24241 atcgcagagc gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa
    24301 gccaagaaaa aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt
    24361 acaggttcaa ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga
    24421 atgaaggctc atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt
    24481 aaaaaaccag cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat
    24541 caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg
    24601 gttagtgaag aaaccgttga ccttggtcat gtagttgatg ctattaaaaa aatagaggaa
    24661 gaaggtcaag gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc
    24721 agcactatct tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa
    24781 gcgatgaggg aagaagcagg cgctgatgac cttgaaactg agcaagacca agctgaaagt
    24841 caagaactag aagacttggg cttgaaagtt gaaacgaact ttgatattga acaagtagct
    24901 acggaagtaa tggcttatgt tcaaacgatt attgatgaca tggatgttga ggctacactt
    24961 tcaaatgatt ataaccgtcg tagcatcaat ttgcaaattg atactaacga accaggtcgt
    25021 attatcggct accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt
    25081 tacaactgct attcaagaac cttctatatc actattaatg tcaatgatta tgttgaacac
    25141 cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga
    25201 cgtagtcatc aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt
    25261 tcacgtatgg atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt
    25321 gtagatacag aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta
    25381 aactgatgtt gaataagata agagactatt tagactttgc tggtttgcag taccgtaatc
    25441 ctgataaagc gggagcagag cgagagaaga tgctggcatt ccgccacaaa ggacaagagg
    25501 cccgaaaggc ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac
    25561 tccaacagac tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt
    25621 atctacagag agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat
    25681 ctactgactt tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa
    25741 cactgggcaa gcaggccaaa gttttagaca ttccaaccgt taaagggatt tattatctaa
    25801 cctactctaa tggtcaaagt caacggtggg aggcgaatga agaaaagcgt cgtactttac
    25861 gcgagaaggt gagaagtcaa gaagctcgaa aagttttagt gaaggtagat gttcctatga
    25921 cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc
    25981 ttccctatta tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag
    26041 tccaagagtg aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat
    26101 ataataaact tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaagtgtt
    26161 ctaaattggt tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg
    26221 ttgataggat atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa
    26281 gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt
    26341 ccaatcttag cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac
    26401 tttggacttg ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact
    26461 gcaactacag ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag
    26521 attacgaagg taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca
    26581 gtatctctta tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg
    26641 attggtatca tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact
    26701 caacgcttga ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg
    26761 tttgtagata aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa
    26821 ttacctaagt tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc
    26881 gtattcttcg gagccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc
    26941 atcacttcag gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa
    27001 acagccttta ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta
    27061 tctgagttga caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca
    27121 gcggttgacg ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt
    27181 acctttggtt tgattggtca attgattaca attgtcttgc tcatcgtctt taaaaatccg
    27241 attcttatta ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac
    27301 gctgataaac gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt
    27361 caagttgctc taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac
    27421 catggaaata tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt
    27481 ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt
    27541 gccaaagcaa aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat
    27601 ctagaaaagg agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc
    27661 atcaatggtt atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt
    27721 tacagtcaat tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt
    27781 aatcgcttct cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg
    27841 gcttgataac ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta
    27901 aaaggttgga gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt
    27961 aaataaagga ggcagatatg aatttaaaac aagctttaat tgacaatgac tcgatccgac
    28021 taggtttaga ggctaacaat tggaaagaag cagtcaaggt agcagtagat cccttaattg
    28081 aaagtggggc aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg
    28141 ggccttacta tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg
    28201 tgcaaagtga tgccttttca ttgattacct tacaaaatcc tgttgtattt tcagatggga
    28261 aagaggtatc tgttttgttg gcactagcag caacaagctc aaaaattcac acaagtgtag
    28321 ccattccaca aattattgcc ctgtttgaat tagacgattc tattgcacgt ttacaggctt
    28381 gccagactaa agaagatgtc ttagctatga ttgaagaatc taaggatagc ccttatctcg
    28441 aaggattgga cttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat
    28501 ttacaagttg cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt
    28561 ggtcaggaag tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa
    28621 ctggctgaag tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt
    28681 gctgatgctg gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact
    28741 tgtatctgtt gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa
    28801 cgaggagaac gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct
    28861 cagctttggc tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt
    28921 cttgctggtg aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg
    28981 ggcttccgtg tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt
    29041 gttgatgtct ttacctttat cgcaggtcgt ggaattacag aggctgcgga tccagcagga
    29101 gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca
    29161 attggaattt atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt
    29221 gccaaggagt taggctttga ttttgtcgag atgtctattg acgaacgtga cgagcgttta
    29281 gcaagacttg actggagtaa ggaagaacgc ttggaagttg tcaaagcaat ctatgaaact
    29341 ggtgttcgta ttccttctat ctgtttttca ggccatcgtc gctacccatt gggttcaaaa
    29401 gatccagttc tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa
    29461 gacttgggag ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca
    29521 ccccagacac gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa
    29581 gctcaggtgg tacttgctat tgaaattatg gatgatcctt tcatcaatag catcgaaaaa
    29641 tatttggcta tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt
    29701 aatgtgtctg catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc
    29761 gcagctctcc atctcaagga tacttatgca gtgacagaaa gttcaagggg ccagttccga
    29821 gatgtacctt ttgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa
    29881 accaattata atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa
    29941 gaaacacgcg cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca
    30001 ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgctgccaa
    30061 tcaatcattg ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagtcaa
    30121 tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc
    30181 tgaaaacatg gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc
    30241 ttccgacctc ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt
    30301 tcacacccat tcgacagaag ctgttgcttg ggctcaggca ggtcgtgata ttcctttcta
    30361 cggaacaacc catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa
    30421 ggacgaagta gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga
    30481 acatcgcgga cttaacccgg ttgaagtacc aggaattgtt gtacgcaatc acggtccatt
    30541 cacctggggc aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc
    30601 aaagatgaat cgctttacag aacaaatcaa tccaagagtt gaacctgctc cccagtacat
    30661 actagaaaaa cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga
    30721 acgatgaagg aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga
    30781 gagtaaagtt ggagttgaag taattttgaa agatttttta gaaatagcgc ttgatatata
    30841 tggtaaaata aaaagaattg ctgtgatatc aatagatttg ggggattttt taatatggta
    30901 ctggataagg caagttgtga tttgcttcaa tatttgatgg atcaagaaac gtccaaaacg
    30961 attatggcga tttcgaaaga tttgaaagag tcaagaagga aaatttatta tcacattgac
    31021 aaaatcaatg ctgctctggt tgacgaggcg cttcacatca ttagtattcc acgaattggt
    31081 attcacttaa cggaagagca gagagatgct tgttgtaaac tattatcgga agtagattcg
    31141 tacgattata tcatgagtgc gcatgaacgt atgatgataa tgttactatg gataggtatt
    31201 tctaaagaac gtattacgat tgaaaaattg atagagttaa cagaggtatc taggaatact
    31261 gttctcaatg atttgaatag tattcgttat caactaactt tggaacaata tcaggtgacc
    31321 ttgcaagtga gcaagtcaca gggataccac cttcatgccc accctcttaa taaaattcag
    31381 tatcttcaat cgcttctata tcatattttt atggaagaaa atgccacttt tgtatctatt
    31441 ttagaagata agatgaaaga gaggttagat gatgagtgtt tgctttctgt tgaaatgaac
    31501 caatttttta aggaacaggt tcctttagtt gaacaagatt tagggaagaa aataaaccat
    31561 catgaaataa cttttatgtt gcaggttcta ccttatttgc tgttaagctg tcataatgtt
    31621 gaacagtatc aagaaagaca tcaggatata gagaaagaat tttctttgat aagaaaaaga
    31681 atagagtatc aggtgtctaa gaaattagga gaacggttgt ttcaaaattt tgaaatttct
    31741 ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc tctcctatcg taaagatttg
    31801 gatattcatg cagaaagtga tgattttcgg caattaaaac ttgctttaga agaatttatc
    31861 tggtattttg aatcacaaat ccgaatggag attgagaaca aggatgattt gttacgaaat
    31921 ttgatgatcc actgtaaagc cttgttattt agaaagactt acggtatttt ttctaaaaat
    31981 cctctaacaa aacaaattcg atccaagtat ggagaattat ttttagtcac tagaaaatct
    32041 gcggaaattt tagaaggagc atggtttatt cggctaacag acgatgatat tgcctatttg
    32101 acgattcata ttggaggatt tttaaagtat acaccatcgt ctcaaaaaaa tatgaaaaaa
    32161 gtttatctcg tttgtgatga aggtgttgcg gtttcgagac ttttgctgaa acaatgcaaa
    32221 ctttattttc caaatgagca aattgacact gtatttacaa cagaacaatt taagagtgtg
    32281 gaagatattg cacaagttga tgtagtgatt actactaatg atgatttgga tagcagattt
    32341 ccgattttaa gggttaatcc tatccttgaa gcagaagata ttttgaaaat gctagactat
    32401 cttaaacaca atatatttcg taataagagc aaaagtttca gtgaaaatct ttctagtctt
    32461 atttcgtctt atattgtaga cagcaagttg gctagtaagt tccaagaaga ggttcaaaca
    32521 cttataaatc aagaaatagt agttcaagct tttttggaag atatttgaag gacagtccaa
    32581 tgatgaacac aaacctgtgt ttttcttggt cttttttagt gttttgaagg gtggtatact
    32641 aatctcaaag ataacaatta tatccaaagg aggcaacata tgccaaacgt caaagaaatt
    32701 acaagagagt catggatttt agccactttc ccagagtggg gaacatggtt gaacgaagaa
    32761 atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt ggtggctagg caactgtggt
    32821 acttggatta agacaccagc tggtgctaac gttgtcatgg acctttggtc aaaccgtgga
    32881 aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc aaatggcaaa tatggcaggt
    32941 gttcgtaagt tgcaaccaaa cttgcgtgtt cagccaatgg ttatcgatcc atttgctatc
    33001 aacgaactag actattactt agtttcacac ttccacagtg atcatatcga cccatacaca
    33061 gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta agtttatcgg tccttaccac
    33121 tgtggacgaa tctgggaagg atggggtgtt ccaaaagaac gtatcatcgt tgttaaacca
    33181 ggtgacacta tcgaattaaa agatatgaag attcatgcag tagaatcatt tgaccgtact
    33241 tgcttggtaa ctctcccagt gaacggtgct gatgagacag gcggtgaact tgctggcttg
    33301 gctgttacag atgaagaaat ggctcaaaag gctgttaact atatctttga aacaccaggt
    33361 ggaaccatct atcatggtgc agattctcac ttctcaaact attttgcaaa acatggtaaa
    33421 gactttaaaa ttgatgttgc tttgaataac tatggtgaaa atccggtagg tatccaagac
    33481 aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc tgcgtaccaa agtcattatc
    33541 ccagttcact atgatatctg gtctaacttc atggcttcta ctaatgagat tctagaactt
    33601 tggaaaatgc gaaaagatcg cttgcaatac gatttccatc catttatctg ggaagttggc
    33661 ggtaagtaca cttatcctca agatcaacac ttagtagaat accatcatcc acgtggtttt
    33721 gatgattgtt ttgaacaaga ctctaacatt caatttaaag ctttgctata atataaaaat
    33781 attctttgga ggttatccgt atgttgcatg atacggataa ttttcatata atagtaaaat
    33841 agaatgtgtg attcaataat cacctcaaat agaaaggaaa ttctatgtca aatctatctg
    33901 ttaatgcaat tcgttttcta ggtattgacg ccattaataa agccaactca ggtcatccag
    33961 gtgtggttat gggagcggct ccgatggctt acagcctctt tacaaaacaa cttcatatca
    34021 atccagctca accaaactgg attaaccgcg accgctttat tctttcagca ggtcatggtt
    34081 caatgctcct ttatgctctt cttcatcttt ctggttttga agatgtcagc atggatgaga
    34141 ttaagagctt ccgtcaatgg ggttcaaaaa caccaggtca cccagaattt ggtcatacgg
    34201 cagggattga tgctacgaca ggtcctctag ggcaagggat ttcaactgct actggttttg
    34261 cccaagcaga acgtttcttg gcagccgaat ataaccgtga aggctacaat atctttgacc
    34321 actatactta cgttatctgt ggagacggag acttgatgga aggtgtctca agcgaggcag
    34381 cttcatacgc aggcttgcaa aaacttgata agttggttgt tctttatgat tcaaatgata
    34441 tcaacttgga tggtgagaca aaggattcct ttacagaaag tgttcgtgac cgttacaatg
    34501 cctacggttg gcatactgcc ttggttgaaa atggaacaga cttggaagcc atccatgctg
    34561 ctatcgaaac agcaaaagct tcaggaaagc catctttaat tgaagtgaag acggttattg
    34621 gatatggttc tccaaacaaa caaggaacta atgctgtaca cggcgcccct cttggagcag
    34681 atgaaactgc atcaactcgc caagccctcg gttgggacta cgaaccattt gaaattccag
    34741 aacaagtata tgctgatttc aaagaacatg ttgcagaccg tggcgcatca gcttatcaag
    34801 cttggactaa attagttgca gattataaag aagctcatcc agaactggct gcagaagtag
    34861 aagccatcat cgacggacgt gatccagtcg aagtgactcc agcagacttc ccagctttag
    34921 aaaatggttt ttctcaagca actcgtaatt caagtcaaga tgccttgaat gttgtggcag
    34981 ctaaattacc aaccttccta ggtggatcag ctgaccttgc tcactcaaac atgacttata
    35041 tcaagacgga tggacttcaa gacgatacca atcgcttgaa tcgtaacatt cagtttggtg
    35101 ttcgtgaatt tgcaatggga acaatcttga acgggatggc ccttcatggt ggacttcgtg
    35161 tatacggtgg aactttcttc gtcttctctg actatgtgaa ggcagctgtc cgcttgtcag
    35221 ccttacaagg acttcctgtg acttatgtct ttacccatga ttcaatcgca gttggggaag
    35281 atggtccgac tcacgaacca gttgagcatt tagcaggtct tcgtgctatg ccaaatctaa
    35341 atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc ttggtacctt gcagtgacaa
    35401 gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa cttgactgtt gaagatggaa
    35461 cagacttcga caaggttgct aaaggtgctt atgttgtata tgaaaatgca gccgactttg
    35521 ataccatctt gattgcgaca ggttcagagg ttaatcttgc tgtctcagct gctaaagaat
    35581 tggctagtca aggcgaaaaa atccgcgtaa tcagcatgcc atctacagat gtctttgata
    35641 aacaaaatgc agcttacaag gaagagattc ttccaaatgc agtccgtcgt cgtgttgcag
    35701 tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg tctcgatggt gccgttctag
    35761 gtattgatac cttcggagcc tctgccccag caccaaaagt attggcagaa tatggcttta
    35821 ctgtagaaaa tcttgtaaaa attgttcgaa acttgaaata atcctaaaaa tcagggcgta
    35881 agctctggtt tttcttgcca gaaaagtaag gtacaatctt gtaaaagtag ctgaaatttg
    35941 atatagtagt cctatgtaaa agacaaagga gaaaacaatg aatccaaata ttactttttt
    36001 aatcatgctt gtaggtatga tggccttgat gttctttatg caacgttctc aaaagaaaca
    36061 agctcaaaag cgtatggaaa gcttaaataa actacaaaaa ggctatgaag tgattacaat
    36121 cggtggactt tatggaacag tcgatgaagt agatacggag aagggaacaa tagttcttga
    36181 cgtagatgga gtttacttga cttttgaact agctgctatc aagacagtat taccgctgaa
    36241 agaaacagct tcactagaag gcgcaattga aaaataagac gggatcacga actcccgttt
    36301 ttctataaaa gaaaggaaat gggatgaaaa aattagtctt tgtctgtctg ggaaatattt
    36361 gccgtagccc tatggccgag tttgttatga aatcaatgac agataactac gaaatccaaa
    36421 gtcgagcaac ttcctcttgg gaacatggca atccgattca taaggggact cagggaattt
    36481 ttcaagagta tgagattcct tatgacaaga acaagacatc gcttcagatt agtaaggaag
    36541 attttgaagc ctttgattat attatcggaa tggacgcttc aaatatttct gacttacgtc
    36601 agatgtgtcc agtagactgt caagataaga tttactcatt ttcatctgaa agtgttccag
    36661 acccttggta tacaggagat tttgaagaaa cctatcgacg tgttcaagag ggctgtcaag
    36721 cttggttaga acgtttagaa aaggagagtt aaggtggaaa atcttacgaa tttttacgaa
    36781 aagtatcgtg tctatctgac tcgtccacgt ttagagcttt tggcagtagt taccattgtt
    36841 ttctgtgctg tactcgtctt ttttctaaat attccaggaa aaggtgtctt aaaactcgat
    36901 aatggaacga ttgtttatga tggcagtctt gtccgtggta aaatgaatgg ccaaggtacc
    36961 attaccttcc aaaatggaga ccaatataca ggtggcttca acaatggagc cttcaacgga
    37021 aaaggtacct ttcaatctaa agaaggctgg acctacgaag gtgattttgt aaatggtcag
    37081 gctgaaggaa aagggaaact aacaacagaa caagaagtcg tttatgaagg aacttttaaa
    37141 caaggcgttt ttcaacaaaa ataaagcctc cttatcaaag gaggtattat tagaatcaca
    37201 aggtaagcgc ttacctgtaa atccctttct ttccaaatcc ctcttccaag caagtttgtg
    37261 aaataaaaaa tatttgaaat aaatttcaca aacttcaaag ataaaacttg ataagaaaag
    37321 aaaatgagaa aagtttcaca agagtttaaa aattctttgt gaaatgttta tgaaactgtt
    37381 tacaaagttg aaataatgcg ttataataaa cttgtgaaaa aattaacaaa ggatatcgtt
    37441 ccttgaaagc tatggaggaa aatatggctg ataaaaaaac tgtgacacca gaggaaaaga
    37501 aactcgttgc tgaaaaacac gtagatgagt tggttcaaaa agctctagtt gcccttgaag
    37561 aaatgcgtaa attggatcaa gaacaagttg actacatcgt tgccaaagca tcagtagcag
    37621 ctttggatgc ccacggagaa ttggctttac atgcctttga agaaacagga cgtggtgtat
    37681 ttgaagacaa agcaactaag aacttgtttg cctgtgaaca cgtagtaaac aacatgcgcc
    37741 acactaagac agttggtgtt atcgaagaag acgatgtaac aggattgact cttattgctg
    37801 aaccagttgg tgttgtttgt ggtattactc caacaacaaa cccaacatca acagcaatct
    37861 tcaaatcatt gatttcattg aagacacgta acccaatcgt ctttgccttc catccatcag
    37921 cacaagaatc atctgctcat gcagctcgta tcgtccgcga tgcagctatc gcagctggtg
    37981 ctcctgaaaa ctgtgtgcaa tggattactc aaccatctat ggaagcaaca agtgccctta
    38041 tgaaccacga aggtgttgcg acaatccttg caacaggtgg taatgccatg gttaaggcgg
    38101 cttattcatg tggtaaacca gctcttgggg taggtgccgg aaacgttcca gcttatgttg
    38161 aaaaatcagc aaacattcgt caagcagcac acgatatcgt catgtctaaa tcatttgata
    38221 acggtatggt ctgtgcatct gaacaagcag ttatcattga taaagaaatt tacgatgaat
    38281 ttgtagcaga gttcaaatct taccacactt actttgtaaa caaaaaagaa aaagctcttc
    38341 ttgaagagtt ctgcttcggt gtcaaagcaa acagcaaaaa ctgtgctggt gcaaaattga
    38401 acgctgacat cgttggtaaa ccagcaactt ggattgcaga acaagcagga tttacagttc
    38461 cagaaggaac aaacattctt gctgcagaat gtaaagaagt tggcgaaaat gagccattga
    38521 ctcgtgaaaa attgtcacca gttattgcag ttttgaaatc tgaaagccgt gaagatggta
    38581 ttactaagac tcgtcaaatg gttgaattta acggtcttgg acactcagca gctatccaca
    38641 cagctgacga agaattgact aaagaatttg gtaaagctgt taaagctatt cgtgttatct
    38701 gtaactcacc ttctactttt ggtggtatcg gggacgttta caatgccttc ttgccatcat
    38761 tgacacttgg atgtggttct tacggacgca actcagttgg ggataacgtt agtgccatta
    38821 acctcttgaa tatcaaaaaa gtcggaagac ggagaaataa catgcaatgg atgaaacttc
    38881 cttcaaaaac atactttgaa cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg
    38941 aacgtgtcat gatcgttact gaccatgcca tggtagagct tggtttcctt gatcgtatca
    39001 tcgaacaact ggaccttcgt cgcaataagg ttgtttacca aatctttgcg gatgtagaac
    39061 cggatccaga tatcacaact gtaaaccgtg gtactgagat tatgcgtgcc ttcaaaccag
    39121 ataccatcat cgcactcggt ggtgggtctc caatggatgc tgccaaagta atgtggcttt
    39181 tctacgagca accagaagtg gacttccgtg accttgtcca aaaattcatg gatatccgta
    39241 aacgtgcctt caagttccca ttgcttggta agaagactaa attcatcgcg attccaacta
    39301 catctggtac aggatctgaa gtaacaccat ttgccgttat ctctgataaa gcaaacaacc
    39361 gtaaataccc aattgctgac tactcattga caccaactgt ggcaatcgta gaccctgctt
    39421 tggtattgac agttccagga tttgttgctg ctgatactgg tatggacgta ttgactcacg
    39481 caacagaagc atatgtatca caaatggcta gtgactacac tgatggttta gcacttcaag
    39541 ccattaaatt ggtctttgaa aatctcgaaa gctcagttaa gaatgcagac ttccactcac
    39601 gtgagaaaat gcataacgct tcaacaatcg ctggtatggc ctttgccaat gccttcttag
    39661 gtatttctca ctcaatggcc cataagattg gtgcgcaatt ccacacaatc cacggtcgta
    39721 caaatgctat cttgcttccg tacgttatcc gttacaatgg tacacgtcca gctaagacag
    39781 caacatggcc taagtacaac tattaccgtg cagatgaaaa ataccaagat atcgcacgca
    39841 tacttggact tccagcttct actccagaag aaggggttga atcttacgca aaagctgtct
    39901 acgaactcgg tgaacgtatt gggatccaaa tgaattttag agaccaagga attgacgaaa
    39961 aagaatggaa agaacattct cgtgaattag ccttcctggc ttatgaagac caatgttcac
    40021 cagctaaccc acgtcttcca atggtagacc atatgcaaga aatcatcgaa gatgcatact
    40081 atggctacaa agaaagacca ggacgccgta aataattgtt tatcagtcta gaagcaagac
    40141 aaaaactcaa tttgagggaa agatccagta atttttctat gataaaaggc atcctatcaa
    40201 ggtttttgaa cacctgatag gatgcctttt tatgatattg aggccttttt gccctttttg
    40261 aaaaactaga atagaaacaa aatatataat agattgaaac tagaatagta cacatctgct
    40321 tctaaaacat tgttagaatt cgatttgact gtcctgatcg atttgtccta ttcctatttc
    40381 attttattat ataaaaaata t
//
LOCUS       DBEJNA010000018        40035 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEJNA010000018 DBEJNA010000000
VERSION     DBEJNA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.18"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(38..1522)
                     /locus_tag="ACL3JB_001066"
     CDS             complement(38..1522)
                     /locus_tag="ACL3JB_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGR0685806.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILEGLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            1738..8856
                     /locus_tag="ACL3JB_001067"
     CDS             1738..8856
                     /locus_tag="ACL3JB_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0685807.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKEDVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPIVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVDLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGAQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGAQGERGLTGAQGAKGEKGDQGERGLTGAQGAKGEKGAQGERGLTG
                     TQGAKGEKGDRGERGLTGTQGAKGEKGDRGERGLTGAQGAKGEKGARGERGLTGAQGA
                     KGEKGAQGERGLTGAQGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKGDQGER
                     GITGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKGAQG
                     QAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRNDADK
                     TTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKGEDG
                     KTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFY
                     YDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITI
                     TQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQ
                     TTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTWEPA
                     GNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGAQGER
                     GLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSL
                     IAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNGKNG
                     VLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIR
                     DGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIKGPK
                     GDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQGKDG
                     DKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDIT
                     FTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTP
                     GTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVI
                     RDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQT
                     PTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRD
                     TDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDN
                     GDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVV
                     KNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSH
                     TVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRD
                     GKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGAD
                     GKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTV
                     KNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTK
                     TVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVP
                     AVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSL
                     YVGRRKEA"
     gene            complement(9093..9641)
                     /locus_tag="ACL3JB_001068"
     CDS             complement(9093..9641)
                     /locus_tag="ACL3JB_001068"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0685808.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            9962..10450
                     /locus_tag="ACL3JB_001069"
     CDS             9962..10450
                     /locus_tag="ACL3JB_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0685809.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            10447..11634
                     /locus_tag="ACL3JB_001070"
     CDS             10447..11634
                     /locus_tag="ACL3JB_001070"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0685810.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            11627..11992
                     /locus_tag="ACL3JB_001071"
     CDS             11627..11992
                     /locus_tag="ACL3JB_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0685811.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            12008..13354
                     /gene="asnS"
                     /locus_tag="ACL3JB_001072"
     CDS             12008..13354
                     /gene="asnS"
                     /locus_tag="ACL3JB_001072"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0685812.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            13507..13797
                     /gene="rpsF"
                     /locus_tag="ACL3JB_001073"
     CDS             13507..13797
                     /gene="rpsF"
                     /locus_tag="ACL3JB_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0685813.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            13809..14279
                     /gene="ssbA"
                     /locus_tag="ACL3JB_001074"
     CDS             13809..14279
                     /gene="ssbA"
                     /locus_tag="ACL3JB_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0685814.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            14311..14550
                     /gene="rpsR"
                     /locus_tag="ACL3JB_001075"
     CDS             14311..14550
                     /gene="rpsR"
                     /locus_tag="ACL3JB_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0685815.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            14845..16245
                     /locus_tag="ACL3JB_001076"
     CDS             14845..16245
                     /locus_tag="ACL3JB_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0685816.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVYLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            16247..16606
                     /locus_tag="ACL3JB_001077"
     CDS             16247..16606
                     /locus_tag="ACL3JB_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0685817.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            16660..17409
                     /locus_tag="ACL3JB_001078"
     CDS             16660..17409
                     /locus_tag="ACL3JB_001078"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0685818.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            17399..17698
                     /locus_tag="ACL3JB_001079"
     CDS             17399..17698
                     /locus_tag="ACL3JB_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0685819.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            17769..18704
                     /locus_tag="ACL3JB_001080"
     CDS             17769..18704
                     /locus_tag="ACL3JB_001080"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0685820.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            18791..19303
                     /locus_tag="ACL3JB_001081"
     CDS             18791..19303
                     /locus_tag="ACL3JB_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0685821.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            19287..19935
                     /locus_tag="ACL3JB_001082"
                     /pseudo
     CDS             19287..19935
                     /locus_tag="ACL3JB_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            20036..20230
                     /locus_tag="ACL3JB_001083"
     CDS             20036..20230
                     /locus_tag="ACL3JB_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0685822.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(20276..21721)
                     /locus_tag="ACL3JB_001084"
     CDS             complement(20276..21721)
                     /locus_tag="ACL3JB_001084"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0685823.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGTTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            21827..23449
                     /locus_tag="ACL3JB_001085"
     CDS             21827..23449
                     /locus_tag="ACL3JB_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0685824.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKVQADRLRAKFKLS"
     gene            23654..25612
                     /locus_tag="ACL3JB_001086"
     CDS             23654..25612
                     /locus_tag="ACL3JB_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0685825.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTKMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            25823..26557
                     /locus_tag="ACL3JB_001087"
                     /pseudo
     CDS             25823..26557
                     /locus_tag="ACL3JB_001087"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            26744..27466
                     /locus_tag="ACL3JB_001088"
     CDS             26744..27466
                     /locus_tag="ACL3JB_001088"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685826.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            27624..28718
                     /locus_tag="ACL3JB_001089"
     CDS             27624..28718
                     /locus_tag="ACL3JB_001089"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0685827.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            28726..29892
                     /locus_tag="ACL3JB_001090"
     CDS             28726..29892
                     /locus_tag="ACL3JB_001090"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0685828.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            29985..33083
                     /locus_tag="ACL3JB_001091"
     CDS             29985..33083
                     /locus_tag="ACL3JB_001091"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0685829.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGPVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            33131..33748
                     /locus_tag="ACL3JB_001092"
     CDS             33131..33748
                     /locus_tag="ACL3JB_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0685830.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRYKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            33759..35093
                     /gene="murC"
                     /locus_tag="ACL3JB_001093"
     CDS             33759..35093
                     /gene="murC"
                     /locus_tag="ACL3JB_001093"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0685831.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            35103..35567
                     /locus_tag="ACL3JB_001094"
     CDS             35103..35567
                     /locus_tag="ACL3JB_001094"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685832.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            35564..36058
                     /locus_tag="ACL3JB_001095"
     CDS             35564..36058
                     /locus_tag="ACL3JB_001095"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685833.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            36139..37794
                     /gene="mltG"
                     /locus_tag="ACL3JB_001096"
     CDS             36139..37794
                     /gene="mltG"
                     /locus_tag="ACL3JB_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0685834.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            37865..38347
                     /gene="greA"
                     /locus_tag="ACL3JB_001097"
     CDS             37865..38347
                     /gene="greA"
                     /locus_tag="ACL3JB_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0685835.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            38856..39254
                     /locus_tag="ACL3JB_001098"
     CDS             38856..39254
                     /locus_tag="ACL3JB_001098"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685836.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            39675..>40035
                     /locus_tag="ACL3JB_001099"
     CDS             39675..>40035
                     /locus_tag="ACL3JB_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0685837.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGIS"
BASE COUNT        12669 a         7320 c         8979 g        11067 t
ORIGIN      
        1 gaaaagtcag cacgattatg ctgacttttt tgataactta taaagtattg gacaaatgaa
       61 tctcatttga taaggtgtta agatgattaa ccaaattcat gattgacaga tgatttcggc
      121 aaataaactt cttggtaatc cctggaatat agaaattaga cacgatgata tcgtaatctg
      181 tctgatttaa aatctcagga cttgttttta attcatccca aatatcgaag gtaaagcggt
      241 tattacagta ataggaaagc atatcaacaa aggtaaggga tatagcatgg tcaaagttac
      301 tgataatcaa aaccttgata ggtggtcgat tttctaacaa ctgagtagag aggttttcag
      361 catgggttaa gatggtgtac atcaagtgtt ccaactgttc aggatggtca tgctgtccaa
      421 ttgcctgacg gtattgagcc aattcttgac gcgcacttcc cataaagtct gggaagtaaa
      481 cttcaaattt tttaatcgtc aatgcttttt gttcaaataa gattggggta gaaaagattt
      541 cctgtctttc aaagaaagca gtgttgtgta aatgccaaat cagctcatcg tggttagtaa
      601 aagtaatctt atattgtttt gataggcctt ctaatatttg actaagtaat tggtaagagt
      661 atcttgcttg actgttatct tctaaagagt tgaagaattc ttgaggatct aggaaaatat
      721 cattctgaag aaaagaaata aaaatttgag cgattgtatc tggagtcatt tcaagcccaa
      781 aatgtttaga gaaataagca agtgtctcct ggaaattcgg aatgctcttt aaaagaggat
      841 aatattcttt gtaaaagtgg ttggggaggt caatgaagtg accattttta accctgtgga
      901 tactgatagc tatcatcagt ttgtacattc tataaattga aaatcgcatt ggataatttg
      961 tgattttata gaagaagtca gcaaactctg ttaaatcttc ctcaggaagg tcaggaaaag
     1021 gccaatctag gaaataatag cgctcagaaa agtattgggc aaaaaagtaa cgaatatcga
     1081 tctcatttcc acgtatctcg gatggagtaa aagataattc aatttgaaac tgagatgaaa
     1141 gaacctttgt aatatttctg cccagtcgat agaggttggc actactaaag taaagatttt
     1201 ctattgttcg ataaataggt agcccctcat tgaagaacat atactctagt aattgaaaag
     1261 attgagaatt agcaagaaag tattgataaa tatcttctac actagtgtta acttctaaat
     1321 ctatcatgat tccgttaaca gaagattgga tgttaataga tggaaaggca atacgtaatt
     1381 catttaaatc actttttaag attcgttctg tacatcctaa tttttcggct agttcatgta
     1441 atttcatcca attacgattc tgaattaggg tttccattaa gcgtaattgt ctttgaactt
     1501 ttgtggataa aaggtttctc atacgggtat ttcctccata attcattata tctttttttg
     1561 tctaagtagt ataaaaaaat tagagcaaga aaattgtcgt tagtaatcgg aaaaattaga
     1621 ataatataag tggcttttaa gtgcaaaaac agaatatatt aattgttcag aaaatattga
     1681 ttaatgcctc aaatagttgt acattgtaaa ctataaaata ctatctagga gtttaaaatg
     1741 aaacattcac ataaaaaatc atttgactgg tatagcatgc aacaacgtta ttctattcgt
     1801 aagtattact ttggtgcagc tagtgtcttg ctcggtaccg ctttggtatt aggtgcagca
     1861 gctagtgtcc aaacagtaca agcggaagaa aacaaacaag aaactaccaa tagtatttct
     1921 gttggtaggg gagaagcagc tactaaacca gcagaggttt ctgcgtctaa taaagagaaa
     1981 acctatgcag ctccaactgt agctaatcca gtagaaacga ctccagttaa aactgaagaa
     2041 gttactaaac cagcagaaaa agttgaagaa gcaaaagaca aaaaagagga agtaacgcat
     2101 caagatgccg ttgacaagtc aaaattatta acggctcttt cgcgtgctaa aaaattagaa
     2161 agcaagttat atacagaagc aagtgctgct aacttgcaaa caagtatcca agctggtcaa
     2221 agcttgcttg gaaaagcaga tgcaactgaa gctgaattat cagcagcaga gtcatctatt
     2281 caatcattta ttattggtct agaacttcgt tctaactcta ataaagaaac tgtatcagaa
     2341 acgcctgtag cgaagaaagc tgatgcagtt gaatcaaaag aaggggctaa accagctgca
     2401 acaactgaac gttcagctgt tgatagcgct attttgccaa ctagcacagc tgacaaagta
     2461 gaaacaactt cagctccagc atctattaat gaaatcttga aactaggttt gagcctttct
     2521 gatgctcgcc aaaatccagc tatccgtaag gaagatgtta atagagggta tagtggtttt
     2581 agagcggcta gcaatccagc caacccaatt gtctcaggtt ctggaaatac agttgcattt
     2641 gcagatatta gccaaggtgg tcgtagctat agtttccgtg gctacgggaa ctcacgtggt
     2701 ggaaattcta ttcattacga tgtaacaaca gtacgtagtg gtaatagtgt taactttaca
     2761 attagttatt ctgcgccagg agattctaga gagtttgtta ataataattt tatcttggat
     2821 aaaggggatg gatttggaaa tccttcaaat gcaacgatca caagttcaaa tccaatagta
     2881 agggagcaat caaaatctat tagtcagggt gccaactacg tatctcactc aggatacagt
     2941 atgacctctg ctatttcaac aaatacggaa caaactatca gatttagttt gcctatcatt
     3001 aatctaaatg gtgatttgtc tgttcgtttg aaacctgtta cttttaacgt ggaccaaggt
     3061 ggtggtggtg ccgctactag caatgaccca tacagtaact ctaactatta ttatagagca
     3121 aacccactat acttggatgc aaacccttat ggtggtacta ataataagac tgtttcagaa
     3181 gacattgact tccaaactgt cgatcttcca actagtaagt taccagaagg tcaaactaga
     3241 ttagttcgag aaggtgaaaa aggacaacgt caaattacct ataaagttca tcgatttggt
     3301 aacgaaacac ttttaggatt gccgattagt aatagtgtta ctaaagaagc taagccacgt
     3361 attatgcaaa ttggtgtggc taaagatcta atcgatacag taaaaccacg tgttgatcaa
     3421 aataaagtcg gtgatacaaa taacctcact ttctatcttg ataacgatgg aaacggtgtt
     3481 tatactgaag gtgtagacga acttgttcaa aaaattgcta ttaaagatgg agctaaaggt
     3541 gaaaaaggag cccaaggtga acgcggtcta actggagcta aaggtgaaaa aggagaccga
     3601 ggcgaacgcg gtctaactgg agctcaagga gctaaaggtg aaaaaggagc ccaaggtgaa
     3661 cgcggtctaa ccggagcaca aggtgccaaa ggtgaaaaag gggaccaagg tgaacgcggt
     3721 ctaaccggag cacaaggtgc taaaggtgaa aaaggagccc aaggtgaacg cggtctaact
     3781 ggaactcaag gagctaaagg tgaaaaagga gaccgaggcg aacgcggtct gactggaact
     3841 caaggagcta aaggtgaaaa aggagaccga ggcgaacgcg gtctgactgg agcccaaggt
     3901 gctaaaggtg aaaaaggagc ccgaggcgaa cgcggtctga ctggagccca aggtgctaaa
     3961 ggtgaaaaag gagcccaagg tgaacgcggt ctaaccggag cccaaggtgc taaaggtgaa
     4021 aaaggggacc aaggcgaacg cggtctaact ggagctcaag gtgaaaaagg agaccgaggc
     4081 gaacgcggtt taactggagc taaaggtgaa aaaggggacc aaggcgaacg tggtatcact
     4141 ggagctaaag gtgaaaaagg agcccaaggt gaacgcggtt taactggagc taaaggtgaa
     4201 aaaggggacc aaggtgaacg cggtctgact ggagcccaag gtgaaaaagg agaccgaggc
     4261 gaacgtggtt taactggagc taaaggtgaa aaaggagccc aaggtcaggc aggtcgtgac
     4321 ggtgtaactc caaccgtaac cgttaaagat aataaaaatg acggcactca tactatcact
     4381 attaacgacg gtagaggtaa tgttacaagt actgttgtaa gagatggttt cgatggcgca
     4441 agtccattag ttgcgactca acgaaatgac gcagataaga caacaactgt tatcttctat
     4501 tacgataaaa atggaaacaa tgaattagat gcttctgata agaaattaaa agaagttgta
     4561 attgcagatg gtgctaaagg tgaaaaaggg gacaaaggtg aacaaggtct tcaagggcgt
     4621 gatggtgaac aaggaccaaa aggagaagat gggaaaaccc caacagttaa agtaactgat
     4681 ggtcaagatg gaacgcatac aattacaatt aacgatggta aaggtggtat aactactaca
     4741 gtagtaagag atggatttga tggtgcaagc cctcttgttt ctactcatag aaatgaagca
     4801 gataaaacaa caactgttat tttctattat gatctaaatg ataataatca atttgatgaa
     4861 ggagatacaa aacttaaaga agttgttatc gcagatggaa aacaaggacc aaaaggtgac
     4921 aaaggtgata acggaaaaga tggattcaca ccagaagtaa cagttacaga taacaataac
     4981 ggaacacaca ccatcacaat cacacaacca gacaacagac catcattaac aacaatcgtt
     5041 aaaaacggtg aagatggaaa aacaccaaaa gtcaaagcag aacgagatga tgcgaagaaa
     5101 caaacaacat taacattcta cattgacaaa gatggagatg gaagttacac agcaggaaaa
     5161 gacgagttag ttcaaacaac agtagttaaa gacggacaag acggagctgc aggagcatct
     5221 ggacgtgatg gaaaagaagt attaaacgga aaagtagacc caacaacaga aggtaaagat
     5281 ggagacacat tcgtaaatac acaaacagga gatgtattcg ttaagaaagg taacacttgg
     5341 gaaccagcag gaaacatcaa aggaccgaaa ggtgacaaag gtgcagatgg tgccaagggt
     5401 gaaaaaggag cccaaggaga acgcggcctg actggagcgc aaggtgtcaa gggtgaaaag
     5461 ggagatcagg gtgaacgcgg tctaactgga tctaaaggtg aaaaaggagc ccaaggtgaa
     5521 cgcggtttaa ctggagcgca aggtgccaaa ggtgacaaag gtgaacaagg tcttcaaggt
     5581 cgtgatggag ctcaaggacc aaaaggcgca gatggacaaa gaggaccagc gggaccacaa
     5641 ggaccaaaag gagaacaagg taatccagga actccaggta aagatggaaa atctctaatt
     5701 gctgttaaaa atggaactga aacaaaagtc tatgtagagg atccggctag accaggacaa
     5761 ccacttaatc caaaccaacc attagcaact atcactgatg gaagaaacgg tactaatgga
     5821 caatcaccaa caattacagc gacacgaagt gtgcaaaatg gcaaaaatgg tgtattagta
     5881 acaattacac cagtaggagg tcgtccacaa acaacatttg tagaggatgg acaaaagggt
     5941 gctgatggga aaaccccaac agtaacaata actgaggggc aaaacggcac acatacatta
     6001 acggttcata atccaggaag tccagatgtg acaactacga tccgtgatgg agctacagga
     6061 caagcaggtc gtgatggtaa agatgtatta aacggaaaag taaatccaca accaaaccaa
     6121 ggtaaaaatg gagataaata tattaatacc gaaaccggtg atgtctatgt taaaaacaat
     6181 ggaaactggg ataaagaagg caacatcaaa ggccctaaag gggacaaagg tgcagatggt
     6241 gctaaaggcg aaaaaggaga ccaaggcgaa cgcggcctaa ctggagcgca aggagctaaa
     6301 ggtgcggatg gcgcagtagg tcgtgatgga cgtgacggta aagacgtgtt gaacggcaaa
     6361 gctaacccag aagcacatca aggtaaagac ggcgataaat acgttaatac agaaacaggc
     6421 gacgtcttcg ttaagaataa cggcaactgg gataaagagg gcaacatcaa aggccctaag
     6481 ggtgacaaag gtgaacgcgg agaagatggt aagactccag aagtaactgt aactccaggt
     6541 aaagatggcc atagtactga cattacattc actgttccag gtaaagatcc agttacagta
     6601 aatgttaagg acggagaaaa tggtctgaac ggtaaaactc caaaagttga tttacttcgt
     6661 gtccaaggaa aaaacggaaa tccatctcat acaattgtga cattctatac agatgaaaac
     6721 aatgacggca aatatacacc aggaactgat gaacttctag gttcagaaat gattaaagat
     6781 ggtgctaaag gcgcggacgg acgagatggt aaatcattgc ttactgtcaa ggatggtaaa
     6841 gaaactaaag tttaccaaga agatccagct aacccaggac aaccattaaa tccagaaaaa
     6901 ccacttgcgg taattagaga tggagtagat ggaaaatcac ctacagttac agctgttcgt
     6961 aaagatgaag cagggcataa aggtgtagaa atcactgttg ataaccatga tggttcacaa
     7021 ccaactacag tctttgttca agatggtgct aagggagaaa ctggtgcaac cggtcaggat
     7081 ggacaaactc ctacaatcac tactcaacgt ggacaagatg gccaaagcac tgttgtaact
     7141 atcacaacat caggtaaaga tccagtaacc ttcactgtaa aagatggtaa gaatggtaaa
     7201 gatggccgtg caccgaaaat caaagtagaa gatattactt caccttcaag aattagacgc
     7261 gatacagatg ctgctgcaac tccaacgcgt aacggtatcc gtgttacagt ttatgatgat
     7321 gttaatgaca atggggtata cgacgaaggt gtcgataaag tattaaatag taaagatatt
     7381 tataacggta tagatggacg tgatggttca gctccaacta ttactacaaa agataatgga
     7441 gatggaactc acactatcac agttcaaaac ccagatggtt ctgaatcaac aacagttgtt
     7501 aaagatggta aagacggtaa aactgcgaat atcactacaa cagaaaaccc agatggaagc
     7561 cacacaatta cggtgacaaa tccagatggt tcaactaaag aaactgttgt taaaaacggt
     7621 aaagacggta agactcctaa agttgaagta acggataaca acgatggaac tcatactgtt
     7681 aaagttacag atggagacgg caatgttacc aacgctatca tcaaagatgg taaagacggt
     7741 aaagctgcaa cagcaacaac tactgaaaat ccagatggaa gccacacagt aacaatcact
     7801 aacccagacg gaactaagaa tgagtttgtt gttaagaatg gacgtgacgg tgttgacgga
     7861 cgtactccaa ccgcatctgt tcgtgataat ggagacggaa gtcatacaat cgttattaca
     7921 aatccagaag gtgtgacaac tgaaaccaca gttcgtgatg gtaaatcacc aaaagtgact
     7981 ataactgatg aacaaaatgg aactcataag atctctgttc taaatggtga cggaacaact
     8041 acaacaacta cagttcgtga tggtagagaa ccaaaacttg aagttattga taacaacgat
     8101 ggttcacaca ctattaaagt gacaggtgct gatggtaaag gaacgacaac tacaatcttt
     8161 gatggtaaat caccaaaagc gaacatcgtt gataacggag atggaactca tacattaaca
     8221 atcgtagatt ctgatggtcg tgaatacaaa tctattatca aagatggtaa agacggcaaa
     8281 gatagcgttt caccaactgt aactgttaaa aataataacg atggaactca cgttgttaca
     8341 atcactaatc cagatggaag taagacagaa atggtgatta aagacggtaa agatggtaaa
     8401 tcaccaaaag tttctgttga agataatggt gatggtagtc atacaatcac aatcatcaat
     8461 tctgatggaa ctgtgacaaa aacagttatt aaagatggta gagatggacg tgatggtcga
     8521 gacggcaaag acggtaaaga cggtaaagat ggaaaatgtg gatgccaaga caaaccagta
     8581 acaccatcaa atgacaaacc agttcctcca acaccaaatg tgccgacacc agaagtaccg
     8641 gttaaacctg tgccagcggt tccagaacaa ccagtagtac caacaccggc tcaaccagca
     8701 actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg tggggacaaa
     8761 ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag cggtattcta
     8821 ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag tcactaattt
     8881 ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag aatgattttc
     8941 ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt ttttggatgg
     9001 ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta ggtggctata
     9061 attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac caagtcttga
     9121 gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc gtctgcccag
     9181 gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg gataaatggc
     9241 aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac agatgatact
     9301 gtgacaaact tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc aagggcacga
     9361 gatagccagt caagcaagtt tttcactgta ccagggatag agaagttgta gactggagag
     9421 aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac agctggatgt
     9481 gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag gtagctaact
     9541 tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt gaaagaacct
     9601 tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct cctttttctt
     9661 aaaatttcga gaactctctc gttgttataa aatatattac aacaaaacaa aagaacttgc
     9721 aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct aatcatttgt
     9781 gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag ggagaaatag
     9841 aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg tttgaagaga
     9901 ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt aaaatagacg
     9961 agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg gtctagggat
    10021 gacgattttg tttgtggtta tcagtggttc ctttctgtat atggtttctc ttagcatgaa
    10081 accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg caggattaga
    10141 gcaggctgat caggttgatt tatacaatgg cttggaatct tattacagcg ttcttggtcg
    10201 taacaaacag caagaagcgc ttgctgtcct gattggtaaa gatgaccata agatttacgt
    10261 ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta aggaaaaggg
    10321 agctggcgag attgacaaga taacctttgg ccgttatcaa gataagccaa tctgggaagt
    10381 taagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg tcaacaagga
    10441 gggcctatga aactatccaa ccgtgtttta gaaatggaag aaagtgtgac tttggctgct
    10501 ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct aaccttgggt
    10561 gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc gattcgagat
    10621 gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc ggcggtcaat
    10681 agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac agtcgctgcg
    10741 ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg tgatgaagtc
    10801 atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc agaaggcgtt
    10861 cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga gcagttagaa
    10921 gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa tcccacaggt
    10981 atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga aaatgatatt
    11041 ctcatcctag cagacgatat ctatggccgc ttggtttata atggtcatga gttcacaccg
    11101 atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg tgtgtctaaa
    11161 acttatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga cattatcgct
    11221 gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc ccaatatgca
    11281 gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca ggcctttgag
    11341 gaacgtctta ataccatcta tcccctcctt gcagaggtac caggatttga agtggtcaaa
    11401 ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat gaaaggctac
    11461 acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc cttggtaaca
    11521 ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga cctagacacg
    11581 cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga ttgatcattt
    11641 tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt ttctcgctcc
    11701 tttggactat aaattggctt ttaagactag ttctctaatt agttttctat ccccgaacag
    11761 ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg ttcattttgc
    11821 ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct tagaggcagg
    11881 tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact atgctgcttt
    11941 tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat aaaaaagaaa
    12001 aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg ttggtcagga
    12061 agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa ggaaaaatcg ctttcttaca
    12121 attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact ttgtcgaaaa
    12181 atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga gccaagaaac
    12241 gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg gctatgagtt
    12301 ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca caccaaaaga
    12361 acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc gtaagcaagt
    12421 agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct ttgacaagaa
    12481 cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag attctacaga
    12541 actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag gtcagcttta
    12601 cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag ttttccgtgc
    12661 tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg ctgagtactc
    12721 atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag ctcttctaca
    12781 aggcgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata cagaactctt
    12841 gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca ttgacctctt
    12901 gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg gtgatgactt
    12961 tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat ttgtcatgaa
    13021 ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc cagagcgcgt
    13081 gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg ggtctatgcg
    13141 tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg atcgtacaga
    13201 atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag gatttggtat
    13261 cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg aagctattcc
    13321 attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc atgtggcgtt
    13381 ttttcgaatt ctagtgtttt tacttgcgta aaaaaatttt ttctagtata atagtttatt
    13441 gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa aaggaggaac
    13501 atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga agaagaagct
    13561 aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc aactgttgtt
    13621 gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt ccgtgaagga
    13681 ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga gtttgaccgt
    13741 ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga cgcgtaagaa
    13801 ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac gctgagttgc
    13861 gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac cgtacattta
    13921 agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg cgccaacagg
    13981 ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca ggtcgtatcc
    14041 agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag gtcgtggctg
    14101 agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt ggagcttact
    14161 ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt tcacgtaatg
    14221 aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta ccattctaat
    14281 ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg cggattcaaa
    14341 cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga ttacaaagat
    14401 actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg tcgtgtaaca
    14461 ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc tcgcgtaatg
    14521 gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cagttgggtc tctttttcat
    14581 gagcttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac aagctttgaa
    14641 atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac aagagaacac
    14701 attaaaagca cgatggagct ttttcataaa tatgtctctt ttctcatcca agaaattaaa
    14761 ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata taatggaaag
    14821 agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc aaagaagatc
    14881 aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg gtttattcca
    14941 actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac aggaatcgcc
    15001 tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaagcc tgactttttt
    15061 gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta tcagcatcag
    15121 attgaaaagt cagatgttga ggagtatatc tcttgggcta agcaagaagg aattgagtat
    15181 ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat gagtgaagct
    15241 atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa agaagatatc
    15301 tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga cagtctctca
    15361 gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc gatttcaggc
    15421 tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc agagaaggtc
    15481 atggtttttg gagatggtct caacgacttg gaactctttg attatgctgg aatcagcgtt
    15541 gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac aaaaacatta
    15601 gaagaagatg gcatttttgc tgccttagaa gtatttggta tggtagaaaa agaattgcat
    15661 tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa gaccaatcac
    15721 ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc taactttgta
    15781 tatctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat caaggacttt
    15841 atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat ctacggcgaa
    15901 tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct ttccatggca
    15961 aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca acacctacct
    16021 tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga aatctatgcc
    16081 aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca gttagctgat
    16141 gaagcatctt acgctgtctt ggatgccatt gctgctgttg agacaggagc tatggacaag
    16201 ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga aaatcggtga
    16261 taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg agttagagac
    16321 gggtgatacg gggctgattc acatttcaga gattcggaca ggatttattg aaaatattca
    16381 tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag atgaatttac
    16441 agggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt ttcctagacg
    16501 gagacgcttt tcaagcgacc gctttaacta cggctttgct ccctttcgac gaatgctacc
    16561 aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta gagttttata
    16621 ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga acaattatta
    16681 aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat tcaaaataga
    16741 gaggttttta gttattcggt ggatagtgtt ctcttatcac gatttccacg ttttcctaag
    16801 aaggggttga ttgtggattt ttgtgctggg aatggagcag tggggctttt tgctagcact
    16861 cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga tatggctgaa
    16921 cgctctgtcc gtttgaatgg attagaggaa caaatgcagg tcatctgcga tgatttgaaa
    16981 aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa tccaccctat
    17041 ttcaaggtgg atcctcattc taatctgaac gagagtgaac attatctctt ggctcgacac
    17101 gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct caagtctaat
    17161 gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga tacgttaaaa
    17221 cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga aaaggaagcc
    17281 aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa ggtcttacct
    17341 cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga gatttattat
    17401 ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact atataggcta
    17461 tacgactgat gtgagaagac gcctcgctat ccacaatagt gggaagggag ccaaatatac
    17521 acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta aggaagaagc
    17581 catgtcggct gaagctcttc tcaagcgtaa gaagaggcca cagaaggaag aatttttatc
    17641 tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag tcctttgact
    17701 cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa acaaaatgag
    17761 gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca gatgccatcg
    17821 gatcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat acggaagctg
    17881 ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt ggtgtggaag
    17941 caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc ttgactgacc
    18001 acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac ggtgttgtag
    18061 accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt ttggagccag
    18121 ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta gctgtgccta
    18181 aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt ttgaaatcac
    18241 caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg gctggtgtga
    18301 acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct agcaaatctg
    18361 ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat aatgtccgtg
    18421 ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca gaaattgaag
    18481 ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg atgattacag
    18541 atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac aaggtcgaag
    18601 cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc gtttcacgta
    18661 agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt gggtgtcagc
    18721 tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc tttttttcta
    18781 ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt cagacatggg
    18841 acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt tggatgggat
    18901 gatttatcat gctagtggac aggctggtgt tgtctgtcaa gaaccggcag acttctttga
    18961 gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt cggtgaagga
    19021 aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag atgcagctgg
    19081 tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta ttcctatgaa
    19141 atttggagat ggggaacagg agattagtga tttttggagg gagtattaca tagaactagg
    19201 tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag catcgcctct
    19261 gttacaatgt aaagaaagga atcttcatga ttcagatttt taatccatct cgtttgacga
    19321 gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg tgattctacg
    19381 ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag agtatataaa
    19441 ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta cgcttgaatc
    19501 acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc cggtctatca
    19561 agccttgttg gagtagagtt ttgagacgga attgcgcaat caaatcaatg cagctatttt
    19621 agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt ttacaaggtc
    19681 aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt aggagatgtt
    19741 aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct caaaaaagac
    19801 cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt aggctatatt
    19861 gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga gagattaact
    19921 ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt agtattcggt
    19981 ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca atcatatgtc
    20041 acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg gtaaagttac
    20101 tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta aggcaaaaga
    20161 cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga aaaacgtttt
    20221 tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc tattcttata
    20281 aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc tggatgattt
    20341 ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga tttgtgatag
    20401 ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga tgattgatgt
    20461 agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca tcagcagtca
    20521 gaaagacttg aatctcaggg tgttgattga ggaggaggcc gaagtcctta cgacgacttt
    20581 ctcccttgtt tcctgttgtt cccagaacca gagcaatctt tccggtttga tgagtttcaa
    20641 ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg aagaccttgg
    20701 ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca gcgatgcctt
    20761 ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca gcaactgcat
    20821 tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt ttacccgtag
    20881 ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta ccatagaaat
    20941 catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg tcactgttaa
    21001 tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag tcttcaaagc
    21061 tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact cctacatcaa
    21121 aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc atgatgaggt
    21181 gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata ctctcagggg
    21241 ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg gtcgacaaca
    21301 tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct gttgtcttac
    21361 ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca tagaactcca
    21421 tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg ataccgactt
    21481 cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa agaaggtatt
    21541 cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact tttcggctgt
    21601 cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga ccttggtcaa
    21661 taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca atcttaatca
    21721 tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa gtttataatg
    21781 gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt cgcacgaaaa
    21841 caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta gtaactttat
    21901 cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg gggcttatgc
    21961 agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt tcttgttggt
    22021 ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata ataccatgcg
    22081 agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga caggactagg
    22141 cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact tgtctggcgt
    22201 gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga ttttcccgtc
    22261 tatgagtgtt attcgaggat ttttccaagg gatgaataac ctcaaaccct atgccatgag
    22321 ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct ttatcattat
    22381 gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg ctgcctttgt
    22441 cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag gttcactcaa
    22501 aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg ataccattaa
    22561 ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga ttttggatca
    22621 gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg acttggttgt
    22681 catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga tttctgtagg
    22741 ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca agggggactt
    22801 gaaagcagct tctcgtctgg ttcaggacag tctcacccta ctctttatgt tcttgctacc
    22861 agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct atggtaagcc
    22921 agatagtttg gctatgggct tatttgtctt tgcagttttg cagtctatta ttttaggttt
    22981 gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg ccgttctcta
    23041 ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg ccctcttcca
    23101 cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg tcttgatgta
    23161 tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc gaaccatttt
    23221 aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt ggctgttagg
    23281 atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc ttgtcggtgc
    23341 catggggggt ggactttata tggttatgag tctgcgtacc tatttattag ataaggtaat
    23401 aggaaaagtc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag gtggcattta
    23461 taaataaaag gaataagttg aacaatcttt taggagaact tgaaacttat tccttttttt
    23521 agcgtcaaaa tagctaaaat tatctttcaa aaatagaaaa tgaggttttt ttcgattttt
    23581 tggaaaaaac aattgactaa acaaacaaag agttgtataa taaaacaaat atttaaagca
    23641 ggaggttctg gaaatgaaaa agtctaagag caaatatcta accttggcag gtcttgtcct
    23701 gggtacagga gttttattga gcgcgtgtgg aaattctagc actgcatcaa aaacctataa
    23761 ctatgtttat tcaagtgatc catctagttt gaactatcta gcagaaaacc gcgcaacaac
    23821 caatgatatt gtgaccaatc tggtagatgg tctcatggaa aatgaccaat atgggaacta
    23881 tgtgccatcc ttggcagaag attggactgt ttctcaggat ggtttgacct atacctacaa
    23941 acttcgtaag gatgccaagt ggtttacttc tgagggagaa gaatatgcac ctgtaactgc
    24001 ccaggatttt gtgacaggat tgcaatatgc agctgataaa aaatcagaag ccttgtatct
    24061 agtgcaggac tctgttgcag gtttggatga ctatatcact ggtaaaacaa gcgacttttc
    24121 aactgtcggt atcaaggctc ttgatgatca aaccgttcaa tacaccttgg ctcgaccaga
    24181 accttactgg aactcaaaaa caacctcaac cattcttttc ccagtcaatg cagatttctt
    24241 gaaatcaaaa ggggatgatt ttggcaaggt agaccctgct aatattttgt acagtggacc
    24301 tttcttgatg aaagcttttg tttcaaaatc tgtcatcgaa tacaagaaaa atcctaacta
    24361 ctgggatgct aaaaatgtct ttgtagacga tgtgaaattg acctactatg atggtagcga
    24421 ccaagaatca ctggaacgta attttacagc tggtgcttat actacggctc gtctttttcc
    24481 taacagctcc agctatgaag ggattaaaga aaaatacaaa aacaatatca tctatagtat
    24541 gcaaaattca acttcatatt tctttaattt taacctagat aggaagtctt acaattatac
    24601 ttctaaaaca agtgacattg aaaagaaatc gactcaggaa gcagttctca ataaaaattt
    24661 ccgtcaggct atcaattttg cttttgacag aacatcttat ggggctcagt ctgaagggaa
    24721 agaaggtgca acaaagattt tgcgtaacct agtggttcct ccaaactttg tcagtatcaa
    24781 gggaaaagac tttggtgaag ttgtagcctc taagatggtc aactatggta aggaatggca
    24841 aggtatcaac tttgcggatg gtcaagaccc ttactacaat cctgagaaag ccaaggctaa
    24901 gtttgcggaa gctaagaaag aactcgaagc aaagggtgtt caattcccaa tccacttgga
    24961 taagactgtg gaagtaacag ataaagtagg catacaagga gttagttcta tcaaacaatc
    25021 aattgaatct gttttaggtt ctgataatgt agtgattgac attcagcaat taacatcaga
    25081 tgagtttgac agttcaggct actttgctca aacagctgct cagaaagact atgatttata
    25141 tcatggcggt tggggacctg attatcaaga cccgtcaacc tatctcgata tttttaatac
    25201 taatagtgga ggagttctac aaaatcttgg actagagcct ggagaagcca atgacaaggc
    25261 taaggcagtt ggactggatg tctatactaa aatgttggaa gaagctaata aagagcaaga
    25321 tccagccaaa cgttatgaga aatatgctga tattcaagct tggttgattg atagttcttt
    25381 agttcttcca agtgtttcgc gtgggggaac accatcattg agaagaaccg taccatttgc
    25441 tgctgcctat ggtttaaccg gtacaaaagg ggttgaatca tataaatacc tcaaagtaca
    25501 agataagatt gtcacaacag acgaatatgc aaaagccaga gaaaaatggt tgaaagaaaa
    25561 agaagaatcc aataaaaaag cccaagaaga attggcaaaa catgtcaaat aaaatctaat
    25621 tgtagataag tttgtgtaag aagtctttgt gcttaaaaac gcataatatc aggtatataa
    25681 aatcctagat gttatgcgtt ttgttatagg aagatttatt agattttatc ctcaaattga
    25741 gttattcccg actttatccg ttgaaatatt ataaggagta tttatgaaat taaaattatt
    25801 aagagtagat actaaggtga ttatggggag tttcttactt gttctgtcta gtctacttgc
    25861 tttgttgctt ccccttatct taaagggttt aatagatggg agttctattg aaaatatagg
    25921 ttccaaagta tttcaatcgt ttttgatttt tattggtcaa gccttgtttt cttctattgg
    25981 ttactatctg tttagtcaat cgggtgaaaa aaagatagca aaaatcagga aaaaagtgac
    26041 agaggggttg atttatgcag agaaatcctt ctttgataag agccaaagtg gggagttgac
    26101 ttctgccatt gtcaatgaca cgagtgtcat tcgtgagttt ttaattacga ctttcccaaa
    26161 tattattctg agtttagtta tggtacttgg ttccattgta gtcttattta gtcttgattg
    26221 gaatctttct ctacttttat tcatcactct tccttgtatg atgtttatta tcttgcccct
    26281 ttccaatatc agtgaaaagt atagtcgtcg tttacaggag gaaatcggat ttttaacagg
    26341 gcaattgact gaaaagattc aagaacatga attaattaag actaaccaag cagagaaaag
    26401 tgtacaggat gttttggata attgtattga aagggtacaa aacaattcac tgaaatcaga
    26461 tagggttact tcttttgaga ccccgtttgc tctcttattt atctttgcga ctatagctgt
    26521 gatgctaacc tatgggggtt atcgggtcag cgcaggatat atatctgtgg gaaccttggt
    26581 ttcgtttttg atttacctct ttcaattact taatcctatt agtaatatag ctaattttgt
    26641 aactgtttat tctaggagca agggatcttc agttgcactg gagaacttgc ttgcagttcc
    26701 taaagaaaaa tttgagggag gaaaatcggt atcaggacaa gggttgaatt ttaaccatgt
    26761 ctattttggt tatgatgaaa atcgacctgt cttaaaggat attacttgtt caattttcaa
    26821 ggggcaaaaa attgcttttg ttggaccatc tggatcagga aaatcaacga ttgtgcgttt
    26881 gttagagcag ttttataaac cgctttcagg agatattcta atggagcaat caagtatata
    26941 tgattttaac ttaaaagaat ggagaagtaa aatcgcttgg gtttcacaaa ataatgcagt
    27001 cttatctggc agtattcgtg acaatctttg tctcggtttg aatcgcttag taactgatga
    27061 tgaattgatg aaagtgctag acttagtatc actaggtgat gagattcgct ccatgaaaga
    27121 gggactagat actgaagttg gtgaacgcgg acgactcttg tcaggggggc gaagccaaag
    27181 acttcaaata gctagagcct acttaaaaga tgctgaaatt cttatatttg atgaagccac
    27241 tgctaatctt gatgcggatt ctgagtatgc gattatcagt agcctctatt ctgtactaaa
    27301 ggagaagacg gttgtgatta tagcgcatcg tttgtcaacg gtaaaagatg tggattgtat
    27361 tttcttctta gaggagggga aaatcactgg ctcaggaact cataaggaac tactggaaaa
    27421 tcatgagcgt tatgctcgtt ttgtgcagga gcaaatgata gagtgaaggt gtcttttgag
    27481 attcaccatt ttatagtcta ttaaagggag caggaaaaac tcccttttta tatagtttga
    27541 aactataact agctcttgaa aagaagaaaa tgagttgatg aaaataagtg gtacaatagt
    27601 tactatagat ttggaggaat tgtatgagca aggaattaca cattaacaca attttagcac
    27661 aagcagggat caagtctgat gaggcaacag gtgctttggt gacaccactt catttttcaa
    27721 cgacctatca gcatccagag tttggtcgat ctactgggtt tgactatacg cgcactaaaa
    27781 atccaactcg tagtaaggct gaggaagtct tggcggctat tgagtcagca gactatgccc
    27841 tagcgactag ctcagggatg tcagctattg tactggcctt tagcgtcttt ccagtaggaa
    27901 gtaaggtctt ggcagtgcgt gatctttacg gtggttcttt tcgctggttt aaccaagtgg
    27961 agcaggaagg tcatttccat tttacctatg ccaatacaga agaagagttg attgccgagt
    28021 tagaaaagga tgtggatgtt ctctatatcg aaaccccaac caatcccttg atgttggaat
    28081 ttgatatcga aaaactagca aaattggctc atgctaaggg tgccaaagtg gtggtggaca
    28141 ataccttcta tagccctatc taccaacgtc cgattgaaga tggagcagat atcgttctcc
    28201 attcagcaac caagtatcta gcaggccaca atgatgtctt ggctggagtg gttgtgacca
    28261 atagtttaga actatacgag aagctttttt acaatcttaa tacaacaggg gcagtcttgt
    28321 ctccatttga cagctaccag ttgcttcgtg gtctcaagac cttgtctctt cgtatggagc
    28381 gctcaacagc taacgcccaa gaagtggttg cctttttgaa ggattctcca gcagttaagg
    28441 aagttctcta cactggtcgt ggaggcatga tttcctttaa agtagccgat gaaacacgca
    28501 ttcctcatat tttgaacagt ctcaaggtct tctcttttgc ggaaagtttg ggtggagtgg
    28561 aaagtcttat tacttatcca acgactcaaa ctcatgctga tattccagca gaagtacgcc
    28621 attcttatgg tttgacagat gacctcttgc gtttgtctat tgggattgag gatgctagag
    28681 atttgattgc agatttgcgc caagccttag aaggataaga caaagatggg aaaatatgat
    28741 tttacaagcc tgcccaaccg tttagggcac catacctata aatggaaaga aacagaaacg
    28801 gatagtgaag ttctaccagc ttggatagcg gatatggact ttgtagtctt gcctgaaatc
    28861 caccaagccg tgcaaactta cgcagaccaa ctggtttatg gttataccta tgccagtgaa
    28921 gacttaatta aggaagttca aaagtgggaa gctacacaat acggttacaa ctttgacaaa
    28981 gaggctcttg tctttatcga gggtgtggta ccagccatct caacagctat tcaaaccttt
    29041 acaaaagaag gcgaggcggt tttaattaac acgcctgtct acccaccctt tgctcgcagt
    29101 gtcaagttga ataatcgtag attgattact aattccttag tggaaaagga tagtctgttt
    29161 gagattgact ttgaccaact tgaaaaggat ttggtggaag aggaggttaa actctatgtt
    29221 ctttgcaacc ctcacaatcc tggtggacgt gtttgggaaa aagaagtgtt ggagaagatt
    29281 ggccaactct gccaaaaaca cggtgttttg ttagtttcgg atgagattca ccaagatttg
    29341 accctctttg gtcacaaaca ccagtctttc aataccatca atcctgcctt caaaaatttt
    29401 gctatcgtct tgagcagtgc cactaaaaca tttaatattg ctggaacaaa aaattcctat
    29461 gcagtcattg aaaatcctaa gttgagactg gctttccaga aacgcctgtt ggccaataat
    29521 cagcatgaaa tttcaggctt gggttatttg gcgacagaag ctgcctatcg atacggtaaa
    29581 gattggctag aggaactcaa gcaagtcttt gaagaccaca tcaattatgt ggtggatcta
    29641 tttggaaaag agactaaaat caaggtcatg aaaccgcaag gtacctactt gatttggctt
    29701 gacttttcag cttatgacct gactgatgaa acattgcaag agttgttgag aaatgaagcc
    29761 aaggttatcc tcaaccgtgg tttggatttt ggagaggaag gaagtctcca tgcccgcatc
    29821 aatatagcta tgcccaaatc tctgttgcaa gaagtctgtc agcggattgt ggctactttt
    29881 gccaaatgtt aaaaatccag ccttctagga gaaaagtctt cctagaaggc tattttcata
    29941 ggcgaaaata tggtataata aaaagataag gtaaaggtga aaatatggct aaattgattc
    30001 cggggaaaat tcgtatcgaa ggtgttgccc tttatgaaac tggtaaggtt gatatcatca
    30061 aggaaaagaa caatcggctc tacgctcgcg ttgcagaaga agaactgcgc tatagtttag
    30121 aggatgattt gattttttgt gcctgtgatt tttttcaaaa gaggggctac tgtgtgcatt
    30181 tggcagcgct agagcatttt ctgaaaaatg atgagcgtgg tcaggaaatc ttgtggagtc
    30241 tggaagaagg tcatgaagaa aaagaggccg ttgaaaccaa ggtgaccttg ggtggcaagt
    30301 ttttggatcg aattttatct ccaaaatcag aatgcgccta tgagttatca gctgtgggtc
    30361 aggtggaagc aggaaccaat catatcttgt ggactctgag aatcggccaa atcaatagcc
    30421 aaaaatacta tgtcattcgg gatattccac tttttttaag gattgtcgag cagagaaagt
    30481 cgtatatgat tggcaagatt tatgaggagt ctctttcttg ggaagccttt gatgatgcca
    30541 gccaagaact tttgactttc ttgcacggac taacggagga agggctggtt ccagacctct
    30601 ttttccaaaa ccaaggtcgg cacctctttt tccctctgac cttttttgag cagggtgtga
    30661 atttactgat ggccttgccc cattttcaat ttgaccatca agtggatagc taccaaaccc
    30721 tgctttttca ggatatgcat gctgatgcca atctatttgc ctttacagta acagaatatt
    30781 cggactattt tgaaatggaa atcagtgaga gtcctagggt caatgtcttt tatcaaggag
    30841 cagtactttt ccataaaggt caggtttatt ttttaacaga ccagcagatg cgtcttctca
    30901 aggaaattaa agcgttacct gtgggtcaac aaggaaagaa atacctgcaa tttgatagca
    30961 gtgatcgaga caaattggcc tcctgtctga ctctttttat ccagatgggc cccgtttcag
    31021 ctccagaacg tctacaaatc aaaacttttg cgccctcttt ttactttgac agggaagaag
    31081 ataatcggat tcgtttagaa attcagtttg attatggaaa tagacaggta tctagccgac
    31141 aagagctaga agaattacca ttttcaagtg acgcggactt agaagaaaga attttccaag
    31201 tctgtttggc tgcgggcttt gaagccgatt ttcaatcttg gcgtcaggcc ttaaaagcgg
    31261 agtctgtcta tcattttttt catgatatca ttccagtctt tgaaaaactc gggcatgttg
    31321 acctatcaga taaactagaa gagctttata gcctagcgag tcctcaggtg caaattgcct
    31381 ccaagggagg tctcttggaa atccagtttg attttcaaga tattgcccag gaggaaatcg
    31441 accaagccat gcaggccttg gttgccaatc aggattttta tattgattcg tctaatcaag
    31501 tttacttttt cgatgaagaa accaagaaaa ttcgccaaaa tctacaggaa ctggggcaat
    31561 ttgaattaaa agatgggacc ttgcaggctc ggaaatcctt ggcctacagt ttagctcatc
    31621 tctttgaagg gcgagaccgt gtttcttttt cacaagaatt ccagaatctg gcccaggatt
    31681 tgacgcatcc agaggacttt cctttgcaag caactcaggt caaggctgac ttgcgagatt
    31741 atcaggaaaa gggaattggc tggttgcaga tgctccatca ttatggtttt ggtgggattt
    31801 tggctgatga tatgggactt gggaaaaccc ttcagaccat tgcttttttg actagtcaag
    31861 tgacaaaaga aagtcgggtt ttgattctcg ctccgtcggg tttgatttac aactgggcag
    31921 atgagtttca gaaatttgct ccacagttgg atgtgactgt tgttcatggt ttgaaagcaa
    31981 gtcgtgagga gattcttgcc gagagccatc aaatctatgt gactagctat gccaccttcc
    32041 gtcaggacag tgagttttat caagggatgg cctttgactt ccttttctta gatgaggctc
    32101 aggtcatgaa aaatgcccag accaagattg cccagacctt gagacaattt gtggtgccgt
    32161 cggtctttgc cttgtcagga actccgattg aaaaccatct gggtgagttg tggtctattt
    32221 tccaaatcgt catgcccgga cttttgccaa gcaagaaaga atttatgaaa ttgccagcag
    32281 agcgagtggc tcagtttatc aagcctttcg tgatgcgacg caagaaagaa gaagttctga
    32341 ctgaattgcc agacttgatt gaggtggttt ataaaaatga actggaagac cagcaaaagg
    32401 ctatttacct tgcccagtta caacagatgc gagaccatct ggctcaagtg tcagaacagg
    32461 aatttcagcg aagtcgtgtg gaaattttat ctggtttgat gcgcttgcgt caaatatgtg
    32521 acactcctgc cctgtttatg gaagattatc agggagccag cggcaaacta gatagtctcc
    32581 gagacctatt ggtacaggtg gcagacggcg gacaccgtgt cttgattttc tctcagttca
    32641 agggaatgtt ggaaaaaatt gaacaagaac tgccagactt gggcctgact tcctttaaaa
    32701 ttacgggttc aaccccagcc aaggaaagac aagacatgac caaggccttt aaccaaggag
    32761 aaagagatgc ctttctgatt tccctcaagg ctggtggggt cggtctgaac ctgacaggtg
    32821 cagatacagt gatcttggtt gacctttggt ggaatcctgc ggtggaagcg caagccattg
    32881 gccgtgccca tcggatgggt caggaagaaa cggttgaggt ctatcgcttg gtgaccaagg
    32941 gaaccattga agaaaaaatt caggaactcc aagaacaaaa gaaacatctg gtgtcacaag
    33001 tattggacgg cacagagtca cgtggtagtc tgaccctagc agaaattaga gaaattttgg
    33061 gaatttctga agccagcact tgaaaaatca agacaatacg ctataatgaa gtgttgaaag
    33121 gaaatagaaa atgaaacaag aacgatttcc attggtgtca gatgacgagg tcatgttgac
    33181 tgaaatgcca gtcatgaatc tctatgatga gtctgatctg atcagtaata tcaagggtga
    33241 gtatcgatat aaaaattatt tagaatgggc tcctattgct gaagaaaaac cagtaaaacc
    33301 gattgaaaag caagtcgaaa aacctaaaaa ggctccttta ggggttaaaa aagaaggaaa
    33361 gagctatgcg gaggtggcgc gtgaagaagc gcgtgcggac ttgaaaaaga aacgctctgc
    33421 taactaccta actcaggatt tcagccttgc gagacgtcat tctcagccca gtctagttag
    33481 acagggcaat caaccgacag ctcctttcca aaaggaaaat cctggtgaat ttgtcaaata
    33541 tagccaaaaa ttgacccagt ctcattatat cttggcggaa gaagttcatt ctatccctac
    33601 caagaatgaa gaagtgtcag cacctgctcc aaagaaaaac aattatgatt ttctaaagaa
    33661 gagccaaatc tacaataaaa aaagtaaaca aacagaacaa gaacgtcggg ttgcccaaga
    33721 gttgaatctg accagaatga cagaataggg gagaaaacat gtcaaagaca tatcatttta
    33781 tcggaattaa gggatcaggg atgagtgcct tggccttgat gttgcaccag atggggcaca
    33841 aggttcaggg atcagatgtt gaaaagtact actttaccca acgcggtctt gagcaggcag
    33901 gaattaccat tcttcctttt gatgaaaaaa atctagacgg tgatatggaa attatcgctg
    33961 gaaatgcctt tcgtccagat aacaacgtcg aaattgccta tgcggaccaa aatggtatca
    34021 gctacaaacg ttaccatgag tttctaggta gctttatgcg tgactttgtt agcatgggag
    34081 tagcaggagc acatggaaaa acttcaacga caggtatgtt gtctcatgtc ttgtctcaca
    34141 ttacagatac cagcttcttg attggagatg ggacaggtcg tggttcggcc aatgccaaat
    34201 attttgtctt tgaatctgac gaatatgagc gtcacttcat gccttaccac ccagaatact
    34261 ctattatcac caacattgac tttgaccatc cagattattt cacaagtctc gaggatgttt
    34321 ttaatgcctt taacgactat gccaaacaaa tcaccaaggg tctttttgtc tatggtgaag
    34381 atgctgaatt gcgtaagatt acgtctgatg caccaattta ttattatggt tttgaagctg
    34441 aaggcaatga ctttgtagct agtgatcttc ttcgttcaat aactggttca accttcaccg
    34501 ttcatttccg tggacaaaac ttggggcaat tccacattcc aacctttggt cgtcacaata
    34561 tcatgaatgc gacagccgtt attggtcttc tttacacagc aggatttgat ttgaacttgg
    34621 tgcgtgagca cttgaaaaca tttgccggtg ttaaacgtcg tttcactgag aaaattgtca
    34681 atgatacagt gattatcgat gactttgccc accatccaac agaaattatt gcgaccttgg
    34741 atgcggctcg tcagaaatac ccaagcaagg aaattgtagc agtctttcaa ccgcatacct
    34801 ttacaagaac cattgccttg ttggacgact ttgcccatgc tttaaaccaa gcagatgctg
    34861 tttatctagc gcaaatttat ggctcggctc gtgaagtaga tcatggtgac gttaaggtag
    34921 aagacctagc caacaaaatc aacaaaaaac accaagtgat tactgttgaa aatgtttctc
    34981 cactcctaga ccatgacaat gctgtttacg tctttatggg agcaggagac atccaaacct
    35041 atgaatactc atttgagcgt ctcttgtcta acttgacaag caatgttcaa taggatgttc
    35101 ccatggaaat tccaattaag atcattcagg caagcaagtc tgatttgcct gagatagggg
    35161 cacttcagac ctcgtctttt ccagctgaaa agcagcaact ttcccatatt ttagaagaaa
    35221 gtatccgtaa gtgtgcggat acctttcttc tagctaggga tgaaaatcaa cttttaggct
    35281 atattttatc aagtccccag tcagacaatc cgcaatgtct aaaagtacat tctttagtca
    35341 tcgagtctga ccatcagaga cagggcctgg gaacacttct tcttgcagcc ttgaaagagg
    35401 tggcagttga gctggattac aaagggattc gtttggagag tcctgatgag ctgctttcct
    35461 attttgaaat gaacggtttt gttgatgaag aagcaacttt gctctatgca actagccagg
    35521 gctatagtat gatttggttt aatccctttt atctggagga acaatgaaaa tcagacaagc
    35581 aagattagaa gatttggatc ggattgttga acttgaattt gaaaattttt cggtcgaaga
    35641 agccattcct ccttctgtct ttgaagcaca tttgagagaa attcagacct cttttctggt
    35701 tgctgaaaaa gaaggaagaa tcatgggtta tatcgaagga ccagttggcc tgcaccgcca
    35761 tctgcaagac cagtctttta cagaagaaat aaaagactat agtcatgagc ctggtggtta
    35821 tatctctgtg acctgtctgt ctattgccaa ggaggcacag ggactcggac tgggtcagaa
    35881 attgctgaca gccttgaaag aagttgctct tgaagatgag agagatggca ttaatctaac
    35941 ctgtcatgac tatctcatcg cctactatga aaaacatgga tttgtcaacg aaggccagtc
    36001 ccagtcaacc tttgcagggg aaacatggta tgatatggtc tgggaaatga aaaaataagt
    36061 taggaaaagt atcatagatt gctttttttg gacttttaag atataatatt atggattatc
    36121 aacaaggagg aaaaactttt gagtgaaaag tcaagagaag aagagaaatt aagctttaaa
    36181 gagcagattc tgagagattt agaaaaagta aaaggctatg atgaagttct gaaagaagat
    36241 gaggcagtag ttcgcactcc tgcaaatgaa ccttcaactg aagaactcat ggctgattcc
    36301 ttgtcaacgg tagaggagat tatgagaaaa gctcctaccg tgcctactca cccaagtcaa
    36361 ggtgtaccag cttctccagc agatgagatt caaagagaaa ctcctggtgt tccaagtcat
    36421 ccaagtcaag atgtaccttc ttctccagcg gaagaaagtg gatcaagacc aggtccaggt
    36481 cctgttagac ctaagaaact tgaaagagaa tacaatgaaa ccccaacaag ggtagctgtt
    36541 tcctatacga cggcagagaa aaaagcagaa caagcaggtc cagaaacacc tacgcctgct
    36601 acagaaacag tggatatcat cagagataca tcacgtcgta gccgtagaga aggagcaaaa
    36661 cccgttaagc ctaagaaaga gaagaagtca catgtgaaag cttttgtgat ttcattcctt
    36721 gtattccttg ccttgctctc agcaggtggt tactttggtt accagtacgt gctagattcc
    36781 ttattaccta tcgatgctaa ttctaagaaa tatgtgacgg ttggaattcc agaaggttca
    36841 aacgttcaag aaatcggtac gacgcttgaa aaagctggtt tggtaaagca tggtctgatt
    36901 tttagttttt atgccaagta taaaaattat accgacttga aagcaggtta ctacaatttg
    36961 caaaagagta tgagtacaga agacttactc aaagagttgc aaaaaggtgg aacagatgaa
    37021 ccgcaagaac ctgtacttgc gactttgaca attccagaag gttatacctt ggatcagatt
    37081 gctcaaactg tgggtcaatt gcaaggtgac ttcaaagagt ctttgacagc ggaggctttc
    37141 ttggctaaag ttcaagatga gacgtttatc agtcaagcag tagcgaaata tcctacttta
    37201 ctggaaagtt tgcctgtaaa agacagcggt gcgcgttatc gtttggaagg ataccttttc
    37261 ccagctacat actctatcaa ggaaagcaca actattgaga gcttgattga tgagatgtta
    37321 gctgctatgg ataagaacct atctccttac tatagtacta tcaaatctaa aaacttgact
    37381 gtcaatgagt tgttgaccat tgcttccttg gtcgaaaaag aaggtgccaa gacagaagat
    37441 cgtaagctca ttgcaggtgt attttacaat cgtttgaatc gtgatatgcc acttcaaagt
    37501 aatattgcaa tcttgtatgc ccaaggaaaa ctggggcaaa atatcagtct agctgaggat
    37561 gttgcgattg ataccaacat tgattcacct tataatgttt ataaaaatgt aggtctcatg
    37621 cctggtccag tcgatagtcc aagtctggat gcgattgagt caagcatcaa tcaaactaag
    37681 agcgataacc tctactttgt agcagatgtc acagaaggca aggtctacta tgctaacaat
    37741 caagaagacc acgaccgcaa tgtcgctgaa catgtcaaca gcaaattaaa ctaaacaaac
    37801 taaaattatg tgatacttca cataattttc tttagaaaat attatcagaa gaaagttgag
    37861 aaaaatggca gaaaaaacat atcctatgac ccttgaggaa aaggagaaac ttgaaaaaga
    37921 attagaagaa ttgaaattgg ttcgtcgacc agaagtggta gaacgcatta agattgcccg
    37981 ttcatacggt gatctttcag aaaacagtga gtacgaagca gctaaggatg aacaagcctt
    38041 tgtcgaagga caaatctcta gcttagaaac aaaaatccgc tatgctgaaa tcgtcaatag
    38101 cgacgcagtt gcccaggacg aagtagcgat tggtaaaaca gtcaccatcc aagaaattgg
    38161 tgaggacgaa gaagaagttt atattatcgt aggttcagct ggtgcggatg cctttgcagg
    38221 taaggtttca aatgaaagcc caattgggca ggccttgatt ggcaagaaaa caggtgacac
    38281 agcaaccatt gaaacgcctg ttggtagcta tgatgtaaaa atcttgaagg ttgaaaaaac
    38341 agcctaaaaa cagaaaaagg agtggggagg cgatgtgctt cactcactcc tttttccatt
    38401 ttgctattct tcgaaaatct cttcaaacca cgtcagcgtc gccttgccgt atgtatggtt
    38461 actgacttcg tcagtttcat ctacaacctc aaaacagtgt tttgagctaa cttcgtcagt
    38521 ttcatctaca acctcaaaac catgttttga gccgacttcg tcagtttcat ctacaacctc
    38581 aaaaccatgc tttgagctga cttcgtcagt ttcatctaca acctcaaaac catgctttga
    38641 gctgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcaac ctgcggctag
    38701 tttcctagtt tgctctttga tttttattga gtattagatg tatagtgcat tgaagttaaa
    38761 aatagtacac tttgatttct aagacattgt tagaaattag attaaattcc ttaatcgatt
    38821 tgcgcatgtt ttatttcatt tcactatact ttagattgga aaataaggaa tcacataaat
    38881 cgcaagaaat agggaatctg attcgtgttt ataaccgttc aaaaagagaa gaggctgaaa
    38941 gtgagccact taatctttat gtcgaagatg aaaagggcaa tctcctggca ggtttgatag
    39001 cagagacttt tggaaattgg ctagaaatcg agtatttgtt tgtaaaagag gaactgcgag
    39061 ggcaaggaat cggttcaaaa ctattgcaac aggcagaaag tgaagctaag aatcgaaatt
    39121 gttgttttgc ctttgtcaat acttaccagt tccaggcacc ggacttttat cagaaacatg
    39181 gctacaagga agttttttct ttgcaagatt atctctacat taggcaaaga tattattacc
    39241 aaaagaatct gtaaggtgag tatggaagtg gactgatata tatgagtaac tatcgataaa
    39301 taccagttat aacctagaaa ttgtgtcttt ctagacgata ttgaggacaa tataatcgta
    39361 gccccaaaat taggaattaa ggcttatcag gttaagaaaa gaagtgatgt tgttgatatt
    39421 ttaaaacaat ttatttaaac taaaaactct ctatcttttt aaattgacat taatccgaga
    39481 ttcccctctc ggattttgtg ttgctttcat taaatttaca ggtaagactt gctagtttca
    39541 gtaaatatac acaagttttt cagaatagag tgaaatccaa aagaaaatgg aaataatgaa
    39601 agctcttgta ggcataagaa aacacctctg tattatactt gttgttcaac cacaaacaca
    39661 agaaaggcac agagatgcaa gacaattata ctacaaaagc caaacatttg acaatcgata
    39721 gccgtcgctt aatcgaaaga tggaaaaaag aagggaaatc aaatagagaa attgcctctc
    39781 tacttggaaa agctcctcaa actatccaca ctgaaatcaa gcgcgggaca gtccgacaat
    39841 gtcttggaaa agggcgcttc aaagaagttt attctgccga ctatgctcaa cagtcttatg
    39901 aaaacaatcg caagcgctcg gtcaagaaat caagcttgac caaggaacta aaggaaaaga
    39961 ttctccacta tcataaccaa aaattttcgc ctgaaatgat ggtgatggct aaaggggtta
    40021 acgtgggaat ttcaa
//
LOCUS       DBEJNA010000019        39322 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEJNA010000019 DBEJNA010000000
VERSION     DBEJNA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.19"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            308..2461
                     /gene="comA"
                     /locus_tag="ACL3JB_001100"
     CDS             308..2461
                     /gene="comA"
                     /locus_tag="ACL3JB_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0685838.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2474..3823
                     /gene="comB"
                     /locus_tag="ACL3JB_001101"
     CDS             2474..3823
                     /gene="comB"
                     /locus_tag="ACL3JB_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0685839.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            3993..4700
                     /gene="purC"
                     /locus_tag="ACL3JB_001102"
     CDS             3993..4700
                     /gene="purC"
                     /locus_tag="ACL3JB_001102"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0685840.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            4757..8482
                     /locus_tag="ACL3JB_001103"
     CDS             4757..8482
                     /locus_tag="ACL3JB_001103"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0685841.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAVGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8575..10017
                     /gene="purF"
                     /locus_tag="ACL3JB_001104"
     CDS             8575..10017
                     /gene="purF"
                     /locus_tag="ACL3JB_001104"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0685842.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10054..11076
                     /gene="purM"
                     /locus_tag="ACL3JB_001105"
     CDS             10054..11076
                     /gene="purM"
                     /locus_tag="ACL3JB_001105"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0685843.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11073..11618
                     /gene="purN"
                     /locus_tag="ACL3JB_001106"
     CDS             11073..11618
                     /gene="purN"
                     /locus_tag="ACL3JB_001106"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0685844.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11702..12211
                     /locus_tag="ACL3JB_001107"
     CDS             11702..12211
                     /locus_tag="ACL3JB_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0685845.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12236..13783
                     /gene="purH"
                     /locus_tag="ACL3JB_001108"
     CDS             12236..13783
                     /gene="purH"
                     /locus_tag="ACL3JB_001108"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0685846.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIAVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYDLTMVFT
                     GVRHFRH"
     gene            13905..15167
                     /gene="purD"
                     /locus_tag="ACL3JB_001109"
     CDS             13905..15167
                     /gene="purD"
                     /locus_tag="ACL3JB_001109"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0685847.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIENHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPMAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIKGLFYRTDIGSKAIK"
     gene            15424..15540
                     /locus_tag="ACL3JB_001110"
     CDS             15424..15540
                     /locus_tag="ACL3JB_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0685848.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            15570..16058
                     /gene="purE"
                     /locus_tag="ACL3JB_001111"
     CDS             15570..16058
                     /gene="purE"
                     /locus_tag="ACL3JB_001111"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0685849.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVISAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDRSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16045..17136
                     /gene="purK"
                     /locus_tag="ACL3JB_001112"
     CDS             16045..17136
                     /gene="purK"
                     /locus_tag="ACL3JB_001112"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0685850.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17146..17373
                     /locus_tag="ACL3JB_001113"
     CDS             17146..17373
                     /locus_tag="ACL3JB_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0685851.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17436..18734
                     /gene="purB"
                     /locus_tag="ACL3JB_001114"
     CDS             17436..18734
                     /gene="purB"
                     /locus_tag="ACL3JB_001114"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0685852.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(18789..22673)
                     /gene="strH"
                     /locus_tag="ACL3JB_001115"
     CDS             complement(18789..22673)
                     /gene="strH"
                     /locus_tag="ACL3JB_001115"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0685853.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKDKPAKKDEAKAEADKPATEAGKERAA
                     TVSEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMS
                     ITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNS
                     PGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAVAFTKALIDKYAAYFAKKT
                     EIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGL
                     KPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAW
                     YYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYS
                     PSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVAAVKEAEKAIRSL
                     DSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNKVISIDAGRK
                     YFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTITANGKTYASDDVKKAIIE
                     GTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNP
                     QAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGW
                     YYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSK
                     GWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLA
                     STKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREEL
                     AKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGLKPAATHS
                     GSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGVKGERTHYIS
                     VLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKPRLDIQKEEI
                     PFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNSVVAQEAVTQ
                     IVEVGTMVTHVGDENGQAAIAEEKPKLEIPRQPAPSTAPAEESKALPQDPAPVVTEKK
                     LPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(22988..23704)
                     /locus_tag="ACL3JB_001116"
     CDS             complement(22988..23704)
                     /locus_tag="ACL3JB_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0685854.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24052..25839
                     /locus_tag="ACL3JB_001117"
     CDS             24052..25839
                     /locus_tag="ACL3JB_001117"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0685855.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKWLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            25836..26312
                     /locus_tag="ACL3JB_001118"
     CDS             25836..26312
                     /locus_tag="ACL3JB_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0685856.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26340..27245
                     /locus_tag="ACL3JB_001119"
     CDS             26340..27245
                     /locus_tag="ACL3JB_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0685857.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27232..28047
                     /locus_tag="ACL3JB_001120"
     CDS             27232..28047
                     /locus_tag="ACL3JB_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0685858.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28054..28458
                     /locus_tag="ACL3JB_001121"
     CDS             28054..28458
                     /locus_tag="ACL3JB_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0685859.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            28757..29923
                     /locus_tag="ACL3JB_001122"
     CDS             28757..29923
                     /locus_tag="ACL3JB_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0685860.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30039..31076
                     /locus_tag="ACL3JB_001123"
     CDS             30039..31076
                     /locus_tag="ACL3JB_001123"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0685861.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31284..32138
                     /locus_tag="ACL3JB_001124"
     CDS             31284..32138
                     /locus_tag="ACL3JB_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0685862.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            32288..32545
                     /locus_tag="ACL3JB_001125"
     CDS             32288..32545
                     /locus_tag="ACL3JB_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HGR0685863.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDCDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(32587..32949)
                     /locus_tag="ACL3JB_001126"
     CDS             complement(32587..32949)
                     /locus_tag="ACL3JB_001126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685864.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFLGSVHSTPDTMR
                     FFNFKDFLQLLLTHIKLF"
     gene            complement(33003..33299)
                     /locus_tag="ACL3JB_001127"
     CDS             complement(33003..33299)
                     /locus_tag="ACL3JB_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0685865.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(33289..33471)
                     /locus_tag="ACL3JB_001128"
                     /pseudo
     CDS             complement(33289..33471)
                     /locus_tag="ACL3JB_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            33520..34284
                     /locus_tag="ACL3JB_001129"
     CDS             33520..34284
                     /locus_tag="ACL3JB_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0685866.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            34894..36273
                     /locus_tag="ACL3JB_001130"
     CDS             34894..36273
                     /locus_tag="ACL3JB_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0685867.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36287..36952
                     /locus_tag="ACL3JB_001131"
     CDS             36287..36952
                     /locus_tag="ACL3JB_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0685868.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37262..37801
                     /locus_tag="ACL3JB_001132"
     CDS             37262..37801
                     /locus_tag="ACL3JB_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0685869.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            37868..38278
                     /locus_tag="ACL3JB_001133"
     CDS             37868..38278
                     /locus_tag="ACL3JB_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0685870.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38394..>39322
                     /gene="pavB"
                     /locus_tag="ACL3JB_001134"
     CDS             38394..>39322
                     /gene="pavB"
                     /locus_tag="ACL3JB_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0685871.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKLEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNV"
BASE COUNT        10799 a         7665 c         9220 g        11638 t
ORIGIN      
        1 tattttctag gtagaacgtt tgttctgcct atttttttat ccaaaaagtg cagttgggag
       61 ggagataggc tcatttggga aggaagtcca gtttttgttt agtgattggg gtaagatagt
      121 tgttatcaga tgagtttata ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt
      181 gccgtatata tgtgactgac ttcgtcagtc ctatctacaa cctcaaaaca gtgttttgag
      241 cagcctgcgg ctagtttcct agtttgctct ttgattttca ttgagtatta gggaaaagga
      301 gatgaatatg aaatttggga aacgtcacta tcgtccgcaa gtggatcaga tggactgcgg
      361 tgtagcttca ttagccatgg tttttggcta ctatggtagt tattattttt tggctcactt
      421 gcgagaattg gctaagacga ccatggatgg gacgacggct ttgggcttgg tcaaggtggc
      481 agaggagatt ggttttgaga cgcgagccat taaggcggat atgacgcttt ttgacttgcc
      541 ggatttgact tttccttttg ttgcccatgt gcttaaggaa gggaaattgc tccactacta
      601 tgtggtgact gggcaggata aggatagcat tcatattgcc gatccagatc ccggggtgaa
      661 gttgactaaa ctgccacgtg agcgttttga ggaagaatgg acaggagtga ctctttttat
      721 ggcacctagt ccagactata agcctcataa ggaacaaaaa aatggtctgc tctcttttat
      781 ccctatatta gtgaagcagc gtggcttgat tgccaatatc gttttggcaa cactcttggt
      841 aaccgtgatt aacattgtgg gttcttatta tctgcagtct atcattgata cctatgtgcc
      901 agatcagatg cgttcgacac tagggattat ttctattggg ctagtcatcg tctacatcct
      961 ccagcaaatc ttgtcttacg ctcaggagta tctcttgctt gttttggggc aacgcttgtc
     1021 gattgacgtg attttgtcct atatcaagca tgtttttcac ctccctatgt ccttctttgc
     1081 gacacgcagg acaggggaga tcgtgtctcg ttttacagat gctaacagta tcatcgatgc
     1141 gctggcttcg accatccttt cgattttcct agatgtgtca acggttgtca ttatttccct
     1201 tgttctattt tcacaaaata ccaatctctt tttcatgact ttattggcgc ttcctatcta
     1261 cacagtgatt atctttgcct ttatgaagcc gtttgaaaag atgaatcggg ataccatgga
     1321 agccaatgcg gttctgtctt cttctatcat tgaggacatc aacggtattg agactatcaa
     1381 gtccttgacc agtgaaagtc agcgttacca aaaaattgac aaggaatttg tggattatct
     1441 gaagaaatcc tttacctata gtcgagcaga gagtcagcaa aaggctctga aaaaggttgc
     1501 ccatctcttg cttaatgtcg gcattctctg gatgggggct gttctggtca tggatggcaa
     1561 gatgagtttg gggcagttga ttacctataa taccttgctg gtttacttta ccaatccttt
     1621 ggaaaatatc atcaatctgc aaaccaagct tcagacagcg caggttgcca ataaccgtct
     1681 aaatgaagtg tatctagtag cttctgagtt tgaggagaag aaaacagttg aggatttgag
     1741 cttgatgaag ggagatatga ccttcaagca ggttcattac aagtatggct atggtcgaga
     1801 cgtcttgtcg gatatcaatt taaccgttcc ccaagggtct aaggtggctt ttgtggggat
     1861 ttcagggtca ggtaagacga ctttggccaa gatgatggtt aatttttacg acccaagtca
     1921 aggggagatt agtctgggtg gtgtcaatct caatcagatt gataaaaaag ccctgcgcca
     1981 gtacatcaac tatctgcctc aacagcccta tgtctttaac ggaacgattt tggagaatct
     2041 tcttttggga gccaaggagg ggacgacaca ggaagatatc ttacgggcgg tcgaattggc
     2101 agagattcga gaggatatcg agcgcatgcc actgaattat cagacagaat tgacttcgga
     2161 tggggcaggg atttcaggtg gtcaacgtca gagaatcgct ttggcgcgtg ctctcttgac
     2221 agatgcgccg gtcttgattt tggatgaggc gactagcagt ttggatattt tgacagagaa
     2281 gcggattgtc gataatctca ttgctttgga caagaccttg attttcattg ctcaccgctt
     2341 gactattgct gagcggacag agaaggtggt tgtcttggat cagggcaaga ttgtcgaaga
     2401 aggaaagcat gctgatttgc ttgcacaggg aggcttttac gcccatttgg tcaatagcta
     2461 gaaagaggag aggatgaaac cagaattttt agaaagtgcg gagttttata atcgtcgtta
     2521 ccataatttt tccagtagtg tgattgtacc catggccctt ctgctcgtgt ttttacttgg
     2581 ctttgcaact gttgcagaga aggagatgag tttgtccact agagctactg tcgaacccag
     2641 tcgtatcctt gcaaatatcc agtcaactag caacaatcgt attcttgtca atcatttgga
     2701 agaaaataag ctggttaaga agggggatct tttggttcaa taccaagaag gggcagaggg
     2761 tgtccaagcg gagtcctatg ccagtcagtt ggacatgcta aaggatcaaa aaaagcaatt
     2821 ggagtatctg caaaagagcc tgcaagaagg ggagaaccac tttccagagg aggataagtt
     2881 tggctaccaa gccacctttc gcgactacat cagtcaagca ggcagtctta gggctagtac
     2941 atcgcaacaa aatgagacca tcgcgtccca gaatgcagca gctagccaaa cccaagccga
     3001 aatcggcaac ctcatcagtc aaacagaggc taaaattcgc gattaccaga cagctaagtc
     3061 agctattgaa acaggtactt ccttggccgg tcagaatcta gcctactctc tttaccagtc
     3121 ctacaagtct cagggcgagg aaaatcccca aactaaggtt caggcagttg cacaggttga
     3181 agcacagatt tctcagttag aatctagtct tgctacttac cgtgtccagt atgcaggttc
     3241 aggtacccag caagcctatg cgtcagggtt aagcagtcaa ttggaatccc ttaaatccca
     3301 acacttggca aaggttggtc aggaattgac ccttctagcc cagaaaatct tggaggcaga
     3361 gtcaggtaag aaggtacagg gaaatctttt agacaagggg aaaattacgg caagtgagga
     3421 tggggtgctt catcttaatc ctgagaccag tgattctagc atggttgcag aaggtgccct
     3481 actagcccaa ctttatccat ctttggaaag agaagggaaa gccaaactca cagcctatct
     3541 aagttcaaaa gatgtagcaa gaatcaaggt cggtgattct gttcgctata ctacgactca
     3601 tgatgccggg aatcaacttt ttctagattc tactattaca agtattgatg cgacagctac
     3661 taagactgag aaagggaatt tctttaaaat cgaggcggag actaatctaa cttcggagca
     3721 ggctgaaaaa cttaggtacg gggtggaagg ccgtctacag atgattacgg gcaagaaaag
     3781 ttatctacgt tattatttgg atcaattttt gaacaaagag taatgttcgt gtttttagag
     3841 ttaaataatt tttaaactgt gagaaagatt cttcttgcag ttttttcttt acaatttttg
     3901 aaaaacatct gctatttatt cggttaaatt cttgtgtttt ttggtttttt gtggtaaaat
     3961 gtgctcaagt aatacgaaag gcgaacttta aaatgtcaaa acaattgatc tattcgggaa
     4021 aagctaaaga tatctataca actgaggatg aaaatcttat tatttcaact tacaaggacc
     4081 aggcgactgc tttcaatggt gtcaagaagg agcagattgc aggtaaggga gtcttgaata
     4141 atcagatttc atcttttatt tttgagaaat taaatgcggc tggtgtggcg actcactttg
     4201 tggagaaact ttcagacacg gaacaactca ataaaaaggt taagattatt cctttggaag
     4261 tcgtgctccg caactatact gctggttcct tttcaaaacg ttttggtgtg gatgagggaa
     4321 tcgccttgga gactccgatt gtcgaatttt actacaaaaa tgatgatttg gatgatccat
     4381 ttatcaatga tgagcatgtg aaattcctac agattgcgga tgaccagcag attgcctact
     4441 tgaaggaaga aacgcgtcgt atcaatgaac tattgaaagt ctggtttgct gagattgggc
     4501 ttaaattgat tgactttaag ctagagttcg gttttgacaa ggatggcaag attatcttgg
     4561 cagacgaatt ttcaccagat aactgccgct tgtgggatgc tgatggcaac cacatggata
     4621 aggatgtttt ccgtagagga ttgggagaac taaccgacgt ttatgagatt gtttgggaaa
     4681 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
     4741 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
     4801 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
     4861 tattcgtatt gtgcaagtat atgatgtatt tgacttggtt gaggacttgt ttgcacctgc
     4921 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
     4981 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
     5041 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
     5101 caacacagcc caactttact tggtgaataa agatattgat gcgactgagt tggaagctgt
     5161 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga tagggattgc
     5221 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgcctttct ttgaaagcta
     5281 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
     5341 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
     5401 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
     5461 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
     5521 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
     5581 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
     5641 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
     5701 ttggctcctc atgtttaaaa acgaaactca caaccatcca acagaaattg agccatttgg
     5761 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
     5821 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
     5881 tgctgggaaa ttgccacaac aagtcatttc taaaacagca actcatggtt attcttcata
     5941 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
     6001 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
     6061 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggtaaaacag gtcgtgatgg
     6121 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
     6181 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
     6241 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gtgtctgtgt
     6301 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
     6361 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
     6421 ggttcgtcct gaagatgtgg ataccttcgt tgccgaatgt aacaaagaaa atattgatgc
     6481 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgcactgga atggtgagac
     6541 aatcgttgac ttggagcgtc gtttccttga catcaatggt gtgcgcgtgg ttgtcgatgc
     6601 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
     6661 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
     6721 gactatcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
     6781 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
     6841 tactgcgtcg gtcattgctc aaggtttcaa cccatatgta gctgaatggt ctccatacca
     6901 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgttg gtgccaactg
     6961 gtccaaggct cgtttctctt accaagaata tttcgagcgt atggacaagc aagcagagcg
     7021 ttttggtcag ccagtagccg ctcttctagg ctctattgaa gctcagattc aacttggctt
     7081 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
     7141 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
     7201 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
     7261 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
     7321 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
     7381 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
     7441 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
     7501 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
     7561 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
     7621 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
     7681 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
     7741 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
     7801 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
     7861 ctttgctggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
     7921 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggttt
     7981 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccctacgg
     8041 aaactttgaa gatgctaaca atactagccc aaccctcttc tacaatgatg ccaaccaaca
     8101 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
     8161 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
     8221 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
     8281 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
     8341 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccattcag aacgttatga
     8401 ggacggtctt ttccaaaata tcccaggcaa taaagaccag cacctgttcg cgtcagcggt
     8461 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
     8521 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
     8581 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
     8641 gctgctaagt tgacctattt tggactccac agtcttcaac accgtggtca ggagggggca
     8701 ggaatcctct ccaatgatca aggacaactg aagcggcatc gcgatatggg tcttctatca
     8761 gaagtcttca gaaatcctgc taacttagat aaattgacgg gaactggtgc gattgggcat
     8821 gtgcgttacg cgactgctgg cgaagcttct gtagataata tccagccctt cctcttccgt
     8881 tttcacgata tgcagtttgg cttggctcat aatggaaatc tgaccaatgc agcctctctc
     8941 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
     9001 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
     9061 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
     9121 cttgacccaa atggattccg accgctttcg attggtaaaa tggctaatgg agcagttgtt
     9181 gtatcttctg aaacctgtgc ttttgaggtc attggtgccg agtggattcg tgatttgaag
     9241 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
     9301 acccagttgg cggtttgttc tatggagtat atctactttg ctcgccctga ttctaatatc
     9361 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
     9421 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
     9481 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
     9541 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
     9601 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
     9661 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
     9721 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
     9781 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
     9841 gacagtatga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
     9901 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
     9961 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    10021 acagattctc cattaaagaa aaggaaaaaa caaatgacaa ataaaaatgc atatgcccag
    10081 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    10141 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    10201 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    10261 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    10321 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    10381 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    10441 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    10501 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    10561 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgtttcaag tgggattcac
    10621 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    10681 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    10741 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    10801 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    10861 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    10921 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    10981 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    11041 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    11101 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    11161 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    11221 ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc gaactcttgg
    11281 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    11341 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctatttg ccagaatttc
    11401 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    11461 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    11521 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    11581 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    11641 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    11701 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    11761 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    11821 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    11881 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    11941 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    12001 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    12061 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    12121 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    12181 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    12241 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    12301 aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc ttgataatgc
    12361 tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga tggatggccg
    12421 tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg atttggatag
    12481 ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag tggtcaacct
    12541 ttatcctttc aaggaaacga ttctcaaacc agacgtgacg tacgctgatg ctgtggagaa
    12601 tattgatatt ggtgggccat ctatgcttcg ttcagcagcg aagaatcatg ccagcgtgac
    12661 ggttgtggta gaccctgctg actatacagt ggttttggac gagttgtcag ccaatggtga
    12721 aacgacttac gaaacgcgtc aacgtttggc agccaaggtt ttccgtcaca cagcggctta
    12781 tgacgctttg attgcagaat acttcacagc tcaagtgggc gaaagcaaac ctgaaaagtt
    12841 gaccttgacc tatgacctaa aacaagctat gcgttatggg gaaaatcccc agcaggatgc
    12901 ggacttctac cagaaagctt tgccgactga ttactccatt gcatcagcca aacagcttaa
    12961 cggtaaggaa ttgtcattca acaatatccg cgatgcagat gctgccattc gtattatccg
    13021 tgacttcaaa gaccgtccaa ccgttgtggc tctcaagcat atgaatccat gtggtatcgg
    13081 ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc cagtgtctat
    13141 ctttggtggt atcgctgttc ttaaccgtga ggtggatgct gcgacagctg agaagatgca
    13201 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    13261 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    13321 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    13381 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    13441 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    13501 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    13561 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    13621 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    13681 catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatacga
    13741 cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga
    13801 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    13861 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctacttgttg
    13921 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    13981 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    14041 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    14101 ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    14161 ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    14221 tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc acattttcag
    14281 atttcgagga agccaaggcc tatatcgaaa atcatggtgc gcctatcgta gtcaaggcgg
    14341 atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    14401 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    14461 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtaaatggt gataagttct
    14521 acatcatgcc aatggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca
    14581 cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta gttgatacag
    14641 cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt cgcccttatc
    14701 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca
    14761 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    14821 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg
    14881 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg
    14941 ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg
    15001 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    15061 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaataa
    15121 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    15181 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    15241 tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat gaaaccgaag
    15301 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    15361 atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc
    15421 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    15481 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    15541 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    15601 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    15661 cctacgaaaa gaaagttatt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    15721 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    15781 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    15841 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    15901 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    15961 tcctctctgt agaagatagg tccattgcgg atgcacttgc caactttgct gaagaacaag
    16021 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    16081 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    16141 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    16201 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    16261 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    16321 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    16381 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    16441 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    16501 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    16561 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    16621 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    16681 aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa agctatggca
    16741 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    16801 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    16861 attgaagcct gtgatttctc tcagtttgac acccatattc tgggtgttct cggagcacca
    16921 ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc
    16981 gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa
    17041 atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat
    17101 agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    17161 gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgccagt
    17221 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    17281 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    17341 tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    17401 tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg
    17461 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    17521 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    17581 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    17641 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    17701 actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg
    17761 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    17821 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    17881 cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg
    17941 agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    18001 atataccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    18061 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    18121 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    18181 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    18241 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    18301 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    18361 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    18421 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    18481 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    18541 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    18601 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    18661 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    18721 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    18781 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    18841 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    18901 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    18961 gctggttgtc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    19021 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    19081 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    19141 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    19201 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    19261 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    19321 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    19381 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    19441 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    19501 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    19561 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    19621 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    19681 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    19741 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    19801 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtattcagcg
    19861 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    19921 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    19981 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    20041 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    20101 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    20161 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    20221 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    20281 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    20341 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    20401 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    20461 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    20521 gctgggatga gaccaatgtc cttagattta gcgtattcaa ttagctctgt cacttctgcc
    20581 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    20641 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcattgagt
    20701 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    20761 gccttgtcta cgatgcgttt gagctggtcc agagtaaagt atttgcgtcc agcatcgatt
    20821 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga
    20881 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    20941 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    21001 tcttttacgg ccgcgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    21061 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    21121 tgacgcatga gtttgaagag gtgtgatggt gaataacgtg cagatggagt gtcagcccaa
    21181 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    21241 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    21301 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    21361 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    21421 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    21481 ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    21541 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    21601 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    21661 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    21721 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgattcctt cccaaaatag
    21781 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtga
    21841 ccaggactat ttactgtcgg aatgagaccg atacctttat cttttgcata gttaatcaga
    21901 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    21961 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    22021 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    22081 tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta
    22141 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcacttac agttgcagca
    22201 cgttcctttc ctgcctctgt tgccggtttg tcagcctctg ctttcgcttc atctttttta
    22261 gctggtttat cctttttagg gctagcttct tctgcctttt tattagcagt ttctttttca
    22321 gcagaagttg gagttaccac ttctgcttta tcactaggag ttgaactaac ttcctcttgt
    22381 ggtttttctt ctgtttttgg aagactagct accttatcag tagctggagt ttctgtttct
    22441 acagtttttg gagcttctgg ttgaagctct gctttaggtg tttcctcagt ccgattttcg
    22501 gatgattgag gggaatcaga aaccgtatgg atggtcggtt ggttttctgt agtagtagga
    22561 gtaactccat cggctgcaac agtctgtgct tggaaggcaa atccaattag aacagaagct
    22621 gctcctacag cgtatttacg aatagaaaaa cgctgttgtt tttcatgttt cattgcaaaa
    22681 cctcctgatt gcattgttat attgatagcg attatataaa tcaacgcctt tattttattt
    22741 cttgttttaa cgagagtcaa gaggagatga caaaaaacta taataagtat aaaaaaatat
    22801 aaaatttaaa cttaagattt cagattggtc gaaaaaatac atatatatat ctagtataat
    22861 ttttggttct atttctataa aatattccac aaattataga atcttccaaa aataggtaag
    22921 cgctaccttt ttggtgtggt ataataagca tagaaaaagc ccgagcgatt aggctcaggc
    22981 tttcttctta gtgatcacgg tcacatgaga tgaatttaat cttgtagtaa tcagatcgtt
    23041 tgtaagtttc actgtattct aaaacttggc cagttgattc gagtttggtg attttagttt
    23101 gtaggacagt agggaattgt tcatcgactc cgaggactga agccgcatgt tctggagttg
    23161 gaaagactat ttcgttgatt tcttcaaagt gttcatcatt catgtgaatg tggtagtcta
    23221 acttgaaacg attatagata gaactatagt attcaaggtt tggataattt gcgttgatat
    23281 attgttctgg gatgtaggat gtatggtaga tataaacgac accgtttgat tcgcggatac
    23341 gttcaatctt gtagtagaat tgatcgccgc gtagacccaa tttttccaag taaacaagct
    23401 tgtttccgcg ttcaattgaa agaacagtta ccttatcatc tttagcattg aagagttcaa
    23461 tatctgaaaa ctctacaagc ttgtgtttgc gtgcacgtga aacgaaggtt ccttttcctt
    23521 gttggcggac aatatagcca tctttggcaa ggtcgtttaa ggcgcgaaca actgtgatag
    23581 agctgacatc gtacattgaa atgagttctg cttcagtgta aaatttatct ccactgctaa
    23641 actgcccaga gatgatttta ttttttaatt cgtcttttat gtattgatat ttgggaattg
    23701 ccatattttt acctctattt tccttctcca tagaaaattt taccataaaa gcgaaaaaaa
    23761 tagtagtctt ttgaataaaa aattagaata atagtttgaa aaattaagcg atatagggat
    23821 tgctcatatt ttatcaatgt attctataca aaattatttt agatcctata ttccgaattt
    23881 aaagagcgtt tgaaatgggt ctaaaaatgt ttgaaactaa ttgaatgtgt gtataatagt
    23941 aaaaatgcag taaatatccc gacaatttct attgacaatt caaacagatt ggtttatgat
    24001 taatataaca acaaatgaaa tcgcaaactt tcgcggtcgg aaggtagttt tatgacacga
    24061 tttgagatac gagatgattt ctatctcgat ggaaaatcat ttaagatttt atctggtgcc
    24121 attcattatt ttagggttcc tccagaggat tggtatcatt cgctctataa cttgaaggct
    24181 cttggtttta atacggtaga gacttatgtt gcttggaatt tacacgagcc tcgtgaaggt
    24241 gagtttcatt ttgaaggtga tctggattta gagaaatttc tccaaatagc gcaggatttg
    24301 ggtctctacg caattgtgcg tccgtctcca tttatctgtg cggaatggga attcggtggc
    24361 ttaccagctt ggctcttgac caagaacatg cgaattcgct catccgaccc agcatatatc
    24421 gaggcagttg gtcgctacta tgatcagtta ttgccaagac tggtgcctcg tttgttggac
    24481 aatggtggca atattctcat gatgcaggtt gaaaatgagt atggttctta cggagaagat
    24541 aaggcttacc tgagagcgat tcgacagcta atggaagagt gtggcgtaac ctgtcccctc
    24601 tttacatcag atggtccatg gcgagctact ctgaaagctg gaaccttaat tgaagaggac
    24661 ctctttgtaa caggaaactt tggttctaag gcaccttaca acttttcgca gatgcaggaa
    24721 ttctttgatg aacatggtaa gaaatggcca ctcatgtgta tggagttctg ggatggttgg
    24781 ttcaatcgct ggaaagaacc gattatcaca cgggatccta aggaattggc agatgcagtt
    24841 cgagaggttt tggaacaagg ctctatcaat ctttacatgt tccacggtgg tacaaacttt
    24901 ggtttcatga atggttgctc agctcgagga actttggacc tgccacaagt tacgtcttat
    24961 gattacgatg cccttctgga tgaagaagga aatccaactg ctaaatatct tgcagtcaag
    25021 aagatgatgg caacacattt ttcagagtat ccgcagttgg aaccactcta caaagagagt
    25081 atggagttgg atgctattcc actagttgaa aaagtttctt tgtttgaaac cttagatagc
    25141 ttgtcaagtc ctgtagaaag tctctatcct caaaagatgg aggagctggg acaaagttat
    25201 ggctacctac tttatcgaac agaaacaaac tgggatgcag aagaagaaag acttcgtatc
    25261 attgatggtc gagatagggc ccagctgtat gtcgatggtc agtgggttaa aactcaatat
    25321 cagacagaga ttggggaaga tattttttat caaggtaaaa agaaatggct atctaggtta
    25381 gatatcttga tagaaaatat ggggcgtgtc aactatgggc ataagttctt agcggatacg
    25441 caacgtaagg gaattcggac aggggtctgt aaggatctgc atttcttact aaactggaaa
    25501 cactatccac tcccactaga caatcctgag aaaattgatt tttcaaaagg atggactcaa
    25561 ggacaaccag ccttttacgc ttatgacttt acagtcgaag agccaaaaga tacttaccta
    25621 gacttgtctg agtttggtaa gggggttgcc tttgtcaatg ggcagaatct aggacgtttt
    25681 tggaacgttg gcccaactct ctcactttat atccctcata gctatctcaa ggaaggtgcc
    25741 aaccgcatca ttatctttga aacagaaggt caatataaag aagagattca tttaactcgt
    25801 aaacctacac taaaacatat aaagggggaa aacttatgac aattgtagga tgccgtattg
    25861 atggacgttt gatccacgga caagtagcca atctttgggc tggaaaacta aatgtttcac
    25921 gcattatggt tgtagacgac gaagttgtca acaacgatat tgaaaagagt ggtttgaaac
    25981 ttgcgacacc accaggtgtg aaattgagta ttttgccagt tgagaaagct gcagccaata
    26041 ttcttgctgg caaatacgat agccaacgtc tctttatcgt ggctcgtaaa ccagaccgct
    26101 tccttggttt ggtagaagca ggtgtaccac ttgaaaccct taatgttggg aatatgtctc
    26161 aaacaccaga aactcgttct attacacgtt ctatcaacgt agtagacaag gatgtggaag
    26221 acttccacaa actggcagaa aaaggtgtta aacttactgc tcagatggtt ccaaatgatc
    26281 caatttcaga ctttttgagc ttattaaaat aggaaaaaat tttttaggag gtcattgtta
    26341 tgatacaatg gtggcaaatt ttacttctca ctttgtactc agcttatcaa atctgtgatg
    26401 agttgacgat cgtttcatct gcaggttccc ctgtatttgc tggtttcatt actggtttaa
    26461 tcatgggaga tgtgactact ggtttactta tcggtggtaa cttgcaactg ttcgttcttg
    26521 gggttggtac cttcggtggt gcttctcgta tcgacgcaac ttctggtgcg gttcttgcga
    26581 cagccttctc tgtttcacaa ggaattgatg caccgcttgc aattactaca atcgctgtac
    26641 cagtagcagc tctcttgact tacttcgacg ttcttggtcg tatgactact accttcttcg
    26701 ctcaccgtgt ggatgctgca atcgaacgct ttgactataa aggtattgaa cgcaactact
    26761 tgcttggtgc gattccgtgg gctctatctc gtgcccttcc agtcttcttt gcccttgctt
    26821 ttggtggtgc ctttgtacaa tcagtagtag acttcgttga agcctacaaa tgggttgcag
    26881 atggcttgac acttgcagga cgtatgcttc caggtcttgg atttgcaatc ttgcttcgtt
    26941 accttccagt taaacgtaac cttcactacc ttgctatggg atttggtttg acagctatgt
    27001 tgactgttct ttactcatat gtaacaggtc ttggtggcgc tgttgctggt atcgtaggta
    27061 ctcttcctgc tgaagttgct gaaaaaattg gtttcgtgaa caacttcaaa ggtttgtcta
    27121 tgattggtat ttctatcgta ggtattttcc ttgcagtgct tcacttcaaa aatagccaaa
    27181 aagtagctgt agcagcacct tctacaccat cagaaagtgg ggaaatcgaa gatgacgaat
    27241 tctaattaca aacttacaaa agaagatttt aatcaaatca acaaacgtag cttgtttact
    27301 ttccaattag gttggaacta cgaacgtatg caagcttctg gttaccttta catgatcttg
    27361 cctcagttgc gtaaaatgta tggtgatgga actcctgaat tgaaagaaat gatgaaagtt
    27421 catactcaat tcttcaatac ttcaccattc ttccatacca ttatcgctgg ttttgacctt
    27481 gccatggaag aaaaagatgg tgtaggttca aaagacgctg ttaacggtat caagacaggt
    27541 ttgatgggac cattcgctcc tcttggggat acaatctttg gttcacttgt acctgctatc
    27601 atggggtcag tcgcagcaac tatggctatc gctggccaac cttgggggat cttcctttgg
    27661 attgcagttg cagtagcgta tgacatcttc cgttggaaac agttggaatt tgcttacaaa
    27721 gaaggggtta accttatcaa caacatgcaa agtaccttga cagctttgat tgacgctgca
    27781 tctgtacttg gtgtcttcat gatgggtgct cttgtagcaa cagtgattaa ctttgaaatt
    27841 tcttacaagt tgccaatcgg tgaaaagatg attgatttcc aagacatctt gaaccaaatc
    27901 ttcccacgtt tgcttccagc aatctttact gcctttatct tctggttgct tggtaaaaaa
    27961 ggtatgaact ctactaaagc tatcggtatt attatcgtac ttgctttggc tctttctgcc
    28021 cttggtcact ttgcacttgg aatgtaattc cttatgacta aatcattaat tttggtgagc
    28081 catggtcgct tctgtgagga gcttagaggt agcacagaaa tgattatggg cccacaagac
    28141 aacatttaca cagtagctct tcttccagaa gatggcccag aagaatttac tgctaaattt
    28201 gaagctgtta ttgaaggatt ggatgatttc ctagtctttg cggatcttct cggtgggaca
    28261 ccttgtaatg tggtgagtcg cttgatcatg gaaggtcgtg atattgacct ttacgcaggg
    28321 atgaatcttc caatggtgat tgaatttatc aatgcgagcc ttacaggcgc agatgcggac
    28381 tacaagagcc gtgctgcaga aagcattgtg aaagttaatg acctgttagc gggcttcgat
    28441 gatgacgaag atgaataata ctcttcgaaa atctcttcaa actacgtcaa cgtcgccttg
    28501 ccgtaggtat atgttactga cttcgtcagt cttatccggc aacctcaaaa cggtgttttg
    28561 agctgacttc gtcagtctta tccggcaacc tcaaagcagt gctttgagca gcctgcggct
    28621 agtttcctac agattttagt tggaactcga ttcaattcat gtgacaacgt gaaaatcgtt
    28681 agagcatttt atatagaata tacatgggaa tggagcttac tcccattccc atatttaata
    28741 gaaaaagagg aactcaatgc tacattatac aaaagaagac ttgctcgaat tgggtgcaga
    28801 aatcactacg cgtgaaatct accaacagcc tgatgtatgg agagaagctt ttgaatttta
    28861 tcaagcaaaa cgtgaagaaa ttgcagcctt tctacaagaa atcgctgata aacatgacta
    28921 tattaaggtt atcttgacag gtgctgggac ttctgcttat gtgggagata ccttgctacc
    28981 ttactttaag gaagtctatg acgaacgcaa atggaatttc aatgctattg cgacaacaga
    29041 tatcgttgcc aaaccagcaa cctatttgaa aaaagatgtg gcaactgtcc ttgtgtcttt
    29101 tgctcgtagt gggaactcgc ctgaaagtgt ggcgactgtt gatttggcca aatccttggt
    29161 ggatgagctt tatcaagtga cgattacttg tgcagcagat ggtaaattgg ctcttcaagc
    29221 tcacggtgat gaccgtaatc tcttgctctt gcaaccagct gtctctaatg atgctggatt
    29281 tgccatgact tctagcttta cgtctatgat gttgacagct ctcttggtct ttgatcctac
    29341 agaatttgct gttaagtctg aacgttttga agttgtatct agtcttgccc gtaaagtttt
    29401 agacaaggta gaagatgtca aagagctcgt tgatttagac tttaaccgtg tcatctatct
    29461 aggcgctggt cctttctttg gacttgctca tgaagctcag ctcaagattt tggaattaac
    29521 tgctggtcaa gttgcgacca tgtatgaaag cccagttggc ttccgtcacg gtccaaaatc
    29581 tcttatcaac gacaatacag ttgttttggt ctttggtaca acgacagcct acactcgtaa
    29641 gtacgacttg gacttggttc gtgaagttgc tggtgaccag attgctcgtc gtgttgtgct
    29701 tttgagtgat caagcttttg gtcttgaaaa tgtcaaagaa gtggcccttg gttgtggcgg
    29761 tgtcttgaat gatatttacc gtgtcttccc ttacatcgtt tatgcccaac tctttgccct
    29821 attgacttca ctcaaggtag aaaataaacc agatacaccg tctcctacag gtacagtaaa
    29881 ccgtgtagta caaggtgtca taattcacga atatcaaaag taagacagtg tttatgaatt
    29941 cttgacaaga ggatttgtaa attatcagat aaaccataga ttgtcagtac gctttctatg
    30001 gtttgtttgc ttgagagaaa tagtaaaagg agaacagaat gaaagcatac acagagcgtg
    30061 tatttggaaa tgttgagggc gaggatgtct tggcctatcg atttgagaca gacggtggct
    30121 accaacttga ggttatgact tatggcgcga ccatcttgcg ctatgtcgca cctgacaagg
    30181 ctggaaattt tgccaatgtt atcttgggat ttgatgactt tgatagttat gtaggcaata
    30241 gtcccaagca tggagcaagt gtaggtcctg tagcgggtcg tattgcaggt gcgacctttg
    30301 agctcaatgg taagacctat gaccttgagg ttaataatgc tagcaactgt aatcacagtg
    30361 gttcaactgg ttgggattcc agcttgtttg aagttgaaga agtaagcgat catggcttga
    30421 ctctctacac agagcgtaca gatgggacag gagggttccc tggaaatctc aagatttgga
    30481 tcagttatca cttggaagaa actggtgcct atgaaatcat ctacaaggta acgaccgatc
    30541 aggatacgct ggtcaatcca accaaccaca gctatttcaa cttgtctggt gatttcacgc
    30601 agacgattga ccgtcatgtc ttccaactaa acacagaggg catttactca atcgctcctg
    30661 acggtgttcc tgccaaaact ccagaagcca accgtgatgt ggtcaaacac atctacaatg
    30721 gtaccttgtt gaaggatatc tttgcagaag aagatgagca aatccagctg gcatcaggtt
    30781 tggatcaccc atttgccctt cctgcaggcc atgacaatgc tggattcctt tatgaccaaa
    30841 attcaggtcg cttcctgctt ttcaagacag aagctccttg ctttgtggtc tacacagcaa
    30901 actttgtgga tgaaagtgtc atcataggag gtcagccaat gctacagcac aatgggattg
    30961 ctcttgaagc gcaagcttta ccagatgcca ttcacagtga ccttaaaggc caagtcattc
    31021 ttaaagctgg tcaaaccttc accagtaaga cacgttatga acttgttgtg aaataaaaaa
    31081 agctggtcaa aaagtcttta aaattaaaat aacgcatatt gtcaggtgat gaaaagtttg
    31141 ataatatgcg ttttattatg aaatgattta ctttatctta tcctgaaatg gtgttatttt
    31201 tgagttatct ggcttgactt tcttgatgga aattatataa tagttgtaat aacaataatt
    31261 acaacgagaa aagaggacca tttatgacct atgaatacaa gagtcacatt tatttggcag
    31321 agacagtttt aaatgtaaag gatttggcca gtcaaacagc cttttatcag caagttattg
    31381 gtttagaaat cttatctcaa actgagacag agtccattct aggccttggt ggaaaagtct
    31441 tggtacagct gattcaagca caagagagcg gagaagtgag ggaacattat ggtctttacc
    31501 atttggccat tctcttgccc acacgcaagg ctttggctga tgtcttgaaa cacctgacag
    31561 atttgcaaat tcctcttgtc ggcggtgcag accatggtta cagtgaagct atttacttgg
    31621 aagatttgga gggaaatggc attgaactct atcgagataa gccagtttcc acatggaata
    31681 ttcgagaaga tggacgcatt atcggagtga cggaggctct tgcggcgcag gacatttatg
    31741 agttggggga aagagtagag ccctttatcc tggcagaagg tacaagaatg gggcatattc
    31801 atctttccgt caaggatagt cgaaagtcca gccagtttta tcaaaaggtg ttagggctag
    31861 agaataaatt cagtgtgcct ggcgctagtt ggattgcggc tggagattac catcatcatt
    31921 tagcagttaa cgaatgggga ggaaaaggtc tggcttcgcg taagcaaggc ttaccaggtt
    31981 tagcctacta tgtcatcgaa gtcgcacaca aaaaagaact attaacgatt gcccaacgag
    32041 cacaagaagt tgacgcacca atcaaatgga tgacatcgag ccaattggaa atcacagact
    32101 cagatggcat cgtgacccgt attcgtttag caaggtaaaa ttaggaattt ttaataagtt
    32161 ataagtattg ctagtttgct ttttgaacgg tctttggtaa cagaactgcg tgagctggat
    32221 gggtgagaat tttgacaaag aagctgatta gagatataat gaagaaaaat cgagcaagga
    32281 aaaagaaatg acaaattcaa agtatattac ttgtttgaaa cgttcagagg gccagttgtg
    32341 tgggattcaa aagatgattg aaggagattg tgactgtgct gatattgtga cgcaactgac
    32401 agcagtgaga tctagtgtag agcgcgtgat tgagatgata attaccgaaa atcttactga
    32461 atgtatcaat cagcccctag atgattctga agctcaaaag gaacgcctag aaaaggctat
    32521 ccgatacttg attaaacgga aataaatgaa tgttttgaga cgatatgtgc aaaggtctat
    32581 taactattag aatagtttaa tgtgagtcaa aagaagttgt aaaaaatctt taaaattaaa
    32641 aaaacgcata gtatcaggtg ttgaatgtac tgaccccaaa aagttagatt ttttctgtct
    32701 aacttttggg gtgcagttca taagaacctt ggtaatatgc gttttattat gtagagactt
    32761 atactcttcg aaaatctctt caaaccacgt cagtttcacc ttgccgtaga tatggttact
    32821 gacttcgtca gttctatcta caacctcaaa acagtgtttt gagctgactt cgtcagttcc
    32881 atccacaacc ttaaaacagt gttttgagca gcctgcggct aacttcctag tttgcacttt
    32941 aattttcatt gagtattact tcatcttctc ctgaaattga gtttttgccc agctcctctt
    33001 gattattcta cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg
    33061 ccttgggagc tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaataaca
    33121 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga
    33181 tttttggcac ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt
    33241 tctagatttt cattttggta ttttccataa aagtcagcca tgctgatact agtttccata
    33301 ttctactcct tctgggttaa ccattttgta tagtgaataa gcgccgtcaa ggttttgggc
    33361 ggtaaatcct gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca
    33421 gctgacgatg taggcttgtt ttttgtccag ttcatcagct tcctccttga cactttgtca
    33481 gtttttgata caatagtaca aaattagagg aggcaggcta tgattcagaa acatgcgatt
    33541 cctattttag agtttgatga caatcctcag gcggttatca tgcccaatca cgaggggttg
    33601 gacttgcagt tgccaaagaa gtgtgtctat gcttttttag gtgaggagat tgaccgctat
    33661 gcgagggaag taggggcgaa ctgtgttggc gaattcgttt ctgctaccaa gacctatcca
    33721 gtctatgtca tcaactacaa gggtgaggag gtctgtctgg ctcaggctcc tgttggctcc
    33781 gctccagcag cccagtttat ggattggttg attggctatg gtgtggagca gattatctct
    33841 actgggacct gtggtgtcct agctgatata gaggaaaatg cctttctagt ccctgttcgc
    33901 gctttgcgag atgagggagc cagttaccac tatgtggcac cttgtcgtta tatggaaatg
    33961 cagccagagg ctattgctgc tattgaggaa gttttggaag acagagggat tccttatgaa
    34021 gaagtcatga cctggacgac agacggtttt taccgagaaa cggctgaaaa ggtggcttat
    34081 cgtaaggaag aaggctgtgc tgttgtggag atggagtgtt ctgctcttgc ggcagtagct
    34141 caattgcgtg gggttctctg gggtgaattg ttgttcacag cagattctct agcggacttg
    34201 gaccagtacg acagtcgtga ctggggctcg gaagctttta ataaggcgct agaactgagt
    34261 ttagcaagtg ttcaccacct ttagttgtac aggcaaagga tttgttttat cataaaatgt
    34321 ctagatcata cttttcaaaa atatgtttaa acgaggtcac cttcctcttg tcctaggcat
    34381 gttgaggttg ggaaaaatct ttaaaatcag aaaaacgtat catatcaggt gatgaaaatt
    34441 ttgatactat gcgttttatg ttggtaagat ttagagtgag atgaaatgat actcttcgaa
    34501 aatctcttca aaccaggtca gcttcacctt gccgtataga tgttactgac ttcgtcagtt
    34561 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    34621 aaacagtgtt ttgagcaacc tgtgactagc tttctaagcg atgccttggt tctcattgcc
    34681 tataatcaaa aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct
    34741 cctgtcttgc ttttttgatc tatagtcaca tctatcaagt attgttcttg cctaagctat
    34801 caataaaaag gtggcatttt ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa
    34861 gtcatttcga gctttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa
    34921 atagagctag gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg
    34981 gtcattttac taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga
    35041 gcgacttatt ttgatcatct tttcactgct gtctctgcag tctgtgtgac aggtctctca
    35101 acccttccag tagctcacac ctataatatc tggggccaaa taatctgttt gctcttgatt
    35161 cagatcggtg gtctagggct catgactttt attggggttt tctatatcca gagcaagcag
    35221 aaacttagtc ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga
    35281 tctttgagaa agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga
    35341 gctattttgc ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt
    35401 tccatttttc tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc
    35461 agtttatttg cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt
    35521 acaggcggcc ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa
    35581 aaaggacgtc tgcactttca tacgaagctt gtactattat tgactatagg tttgttgtta
    35641 tttggaacag caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc
    35701 cctgttgccg ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc
    35761 ttttctacga tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag
    35821 atgtttctag gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt
    35881 gtcctcttgg tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga
    35941 cgaacgatcg cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg
    36001 agcttcttga taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc
    36061 cacctcgtat ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact
    36121 cctgaccttg ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt
    36181 ggtcccttga ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt
    36241 cactatatga aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac
    36301 gattggaatt ttgggcttgg gaatttttgg gagcagtgtc ctagctgccc tagccaagca
    36361 ggatatgaat attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt
    36421 tttggcgcgt ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat
    36481 tgatacctgc gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc
    36541 ggttatgcac tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac
    36601 cgctaagaaa gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat
    36661 ggggcagtct ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga
    36721 taaaaatgtg tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag
    36781 taaattagac ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa
    36841 ttccccattg gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt
    36901 ggcagtcatc aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat
    36961 gacccctctt ttttgatgcc taagatggca aatagagaca gaagcccctt gtcttctagt
    37021 aaaagttctt caaaggctgg actttatggt aaaatagaaa gaagtgacaa gagagagtaa
    37081 tactcaatga aaatcaaaga tcaaactagg aaactagcta cgggctgctc aaaacactgt
    37141 tttgaggttg cagatagaac tgacgaagtc agtaacatct atacggcaag gcgacgttga
    37201 cgcggtttga agagattttc gaagagtata agaaaaaatc agtcccctaa aggagtagat
    37261 tatgaagtta ttgtctatcg caatttctag ctataatgca gcagcctatc ttcattactg
    37321 tgtggagtcg ctagtgattg gtggtgagca agttgggatt ttgattatca atgacgggtc
    37381 tcaggatcag actcaggaaa tcgctgagtg tttagctagc aagtatccta atatcgttag
    37441 agccatctat caggaaaata aatgccatgg cggtgcggtc aatcgtggct tggcagaggc
    37501 ttctgggcgc tattttaaag tagttgacag tgatgactgg gtggatcctc gtgcctactt
    37561 gaaaattctt gaaaccttgc aggaacttga gagcaaaggt caagaggtgg atgtctttgt
    37621 gaccaatttt gtctatgaaa aggaagggca gtctcgtaag aagagtatga gttacgattc
    37681 agtcttgcct gttcggcaga tttttggctg ggaccaggtc ggaaatttct ccaaaggcca
    37741 gtataccatg atgcactcgc tgatttatcg gacagatttg ttgcgtgcta gccagttcta
    37801 actgcctgaa catacttttt atgtcgataa tctctttgtc tttacgcccc ttcagcaggt
    37861 caagaccatg tactatctgc ctgtcgattt ctatcgttat ttgattgggc gtgaggacca
    37921 gtctgtcaat gagcaagtga tgattaagtg cattgaccag caactcaagg tcaatcgact
    37981 cttgatagac caacttgatt tgtcccaagt gagtcatccc aaaatgcgag aatatctgct
    38041 gaatcatatt gaactcacga cggtgatttc cagtaccctg ctcaaccgat ctggaacagc
    38101 ggagcatctg gcaaaaaaac gccaattgtg gacctatatt cagcagaaaa atccagaagt
    38161 ctttcaggct attcgtaaga ccatgttgag ccgtttgacc aaacattctg tcttgccaga
    38221 tcgcaaactg tccaatgtcg tctatcaaat caccaaatct gtttatggat ttaattaata
    38281 taagtgtttt ataagaggga tttaagaaaa attttaactt tttcttagtc ctttttaatt
    38341 tcaggagatt atactagagt catcaaataa agaaagactc taaggagaat cctatgaaat
    38401 tcaatccaaa tcaaagatat actcgttggt ctattcgccg tctcagtgtc ggtgttgcct
    38461 cagttgttgt ggctagtggc ttctttgtcc tagttggtca gccaagttct gtacgtgccg
    38521 atgtggtcaa tccgacccca ggtcaagtct tacctgaaga gacatcggga acgaaagagg
    38581 gtgacttatc agaaaaacca ggagacaccg ttctcactca agcgaaactt gagggcgtta
    38641 ctggaaatac gaattcactt ccgacaccta cagaaagaac tgaagtgagc gaggaaacaa
    38701 actcttctag tctggataca ctttttgaaa aagatgaaga agctcaaaaa aatccagagc
    38761 taacagatgt cttaaaagaa actgtagata cagctgatgt ggatgggaca caagcaagtc
    38821 cagcagaaac tactcctgaa caagtaaaag gtggagtgaa agaaaataca aaagacagca
    38881 tcgatgttcc tgctgcttat cttgaaaaag ctgaagggaa aggtcctttc actgccggtg
    38941 taaaccaagt aattccttat gaactattcg ctggtgatgg tatgttaact cgtctattac
    39001 taaaagcttc ggataatgct ccttggtctg acaatggtac tgctaaaaat cctgctttac
    39061 ctcctcttga aggattaaca aaagggaaat acttctatga agtagactta aatggcaata
    39121 ctgttggtaa acaaggtcaa gctttaattg atcaacttcg cgctaatggt actcaaactt
    39181 ataaagctac tgttaaagtt tacggaaata aagacggtaa agctgacttg actaatctag
    39241 ttgctactaa aaatgtagac atcaacatca atggattagt tgctaaagaa actgtcgaaa
    39301 aagctgttaa agataacgtt aa
//
LOCUS       DBEJNA010000020        36992 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEJNA010000020 DBEJNA010000000
VERSION     DBEJNA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.20"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            82..315
                     /locus_tag="ACL3JB_001135"
     CDS             82..315
                     /locus_tag="ACL3JB_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0685872.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            315..1649
                     /locus_tag="ACL3JB_001136"
     CDS             315..1649
                     /locus_tag="ACL3JB_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0685873.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            1659..1913
                     /locus_tag="ACL3JB_001137"
     CDS             1659..1913
                     /locus_tag="ACL3JB_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0685874.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            2009..2404
                     /locus_tag="ACL3JB_001138"
     CDS             2009..2404
                     /locus_tag="ACL3JB_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0685875.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            2687..3264
                     /locus_tag="ACL3JB_001139"
                     /pseudo
     CDS             2687..3264
                     /locus_tag="ACL3JB_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            3251..3811
                     /locus_tag="ACL3JB_001140"
     CDS             3251..3811
                     /locus_tag="ACL3JB_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0685876.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFL
                     PVKTLEDEIYYLVHILPNRNQKENFPAGYGIVVKGTDKVIGSVDFNHRHEDDVLEIDY
                     TLHPDYWGRGYVPEAARTLIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            3811..4389
                     /locus_tag="ACL3JB_001141"
     CDS             3811..4389
                     /locus_tag="ACL3JB_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0685877.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            4382..7033
                     /locus_tag="ACL3JB_001142"
     CDS             4382..7033
                     /locus_tag="ACL3JB_001142"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0685878.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAQSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVVNAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            7114..8205
                     /locus_tag="ACL3JB_001143"
     CDS             7114..8205
                     /locus_tag="ACL3JB_001143"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGR0685879.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDKDINVVSGDEVKEYLKIDTDDKLMLVACPPCQGFSTIGTNNENDERNQLV
                     FQFLRLINELNPDFLLMENVVGMTRTRNEKIFKKFLTSIDNNYSVIYDILNTADYGVP
                     QSRKRLVLHGIRKEILDNTNLTLNLPSKTHSNIPELDLLSWINADIIMDLPPIEGGEE
                     YIGEGIYNHVANKLSNLNIERITHIRNNGGSRTSLPKSLELNCHKNRLGHSDVYGILD
                     INKPSITITGGCMSYSKGRFGHPTQNRALSAREAARLQSFDDDYIFVGNRGQLAKQIG
                     NAVPVKLAQASGNYFMSVYREIANGQSDN"
     gene            8414..10018
                     /locus_tag="ACL3JB_001144"
     CDS             8414..10018
                     /locus_tag="ACL3JB_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0685880.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNIKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            10039..10180
                     /locus_tag="ACL3JB_001145"
                     /pseudo
     CDS             10039..10180
                     /locus_tag="ACL3JB_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155197.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            10398..11201
                     /locus_tag="ACL3JB_001146"
     CDS             10398..11201
                     /locus_tag="ACL3JB_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR0685881.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            11473..12843
                     /locus_tag="ACL3JB_001147"
                     /pseudo
     CDS             11473..12843
                     /locus_tag="ACL3JB_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397831.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            12855..14255
                     /locus_tag="ACL3JB_001148"
     CDS             12855..14255
                     /locus_tag="ACL3JB_001148"
                     /inference="COORDINATES: protein motif:HMM:NF012492.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0685882.1"
                     /translation="MSERKTKTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGR
                     EKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMF
                     EKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSF
                     AHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFE
                     KLLKEKEVDGCYIISGKTKVRERTSLLEILEQLDKGFVLLSTGKYIGEGFDLPQLDTL
                     ILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDY
                     RAIEGEEKQFVYVDSRYENVLRKDLAGERQECLLVLPYVHQTKLMNFLKEFRISQIEI
                     CIPETVANKAWLDQLKSKKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            14555..15394
                     /gene="licT"
                     /locus_tag="ACL3JB_001149"
     CDS             14555..15394
                     /gene="licT"
                     /locus_tag="ACL3JB_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR0685883.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            15412..17250
                     /locus_tag="ACL3JB_001150"
     CDS             15412..17250
                     /locus_tag="ACL3JB_001150"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0685884.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFVVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            17263..18678
                     /locus_tag="ACL3JB_001151"
     CDS             17263..18678
                     /locus_tag="ACL3JB_001151"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0685885.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            19269..20315
                     /gene="pheS"
                     /locus_tag="ACL3JB_001152"
     CDS             19269..20315
                     /gene="pheS"
                     /locus_tag="ACL3JB_001152"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0685886.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            20315..20824
                     /locus_tag="ACL3JB_001153"
     CDS             20315..20824
                     /locus_tag="ACL3JB_001153"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685887.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTVSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            20901..23306
                     /gene="pheT"
                     /locus_tag="ACL3JB_001154"
     CDS             20901..23306
                     /gene="pheT"
                     /locus_tag="ACL3JB_001154"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0685888.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVIIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(23374..24374)
                     /locus_tag="ACL3JB_001155"
                     /pseudo
     CDS             complement(23374..24374)
                     /locus_tag="ACL3JB_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
     gene            24530..25019
                     /locus_tag="ACL3JB_001156"
                     /pseudo
     CDS             24530..25019
                     /locus_tag="ACL3JB_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25104..25370
                     /locus_tag="ACL3JB_001157"
     CDS             25104..25370
                     /locus_tag="ACL3JB_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0685889.1"
                     /translation="MEGCLSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEV
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            25630..27879
                     /gene="metE"
                     /locus_tag="ACL3JB_001158"
     CDS             25630..27879
                     /gene="metE"
                     /locus_tag="ACL3JB_001158"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0685890.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            27943..28809
                     /gene="metF"
                     /locus_tag="ACL3JB_001159"
     CDS             27943..28809
                     /gene="metF"
                     /locus_tag="ACL3JB_001159"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0685891.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDIAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(28991..29260)
                     /locus_tag="ACL3JB_001160"
     CDS             complement(28991..29260)
                     /locus_tag="ACL3JB_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine methyltransferase"
                     /protein_id="HGR0685892.1"
                     /translation="MLGSLSFFLRNETKIQLLKILSRQATQRKIGNRTTERLLLGRFI
                     FFHRVVGKFSFQDTSLERFNTKVSKAFTLIAIGRLAKCFTNSLVK"
     gene            29494..31707
                     /gene="pnp"
                     /locus_tag="ACL3JB_001161"
     CDS             29494..31707
                     /gene="pnp"
                     /locus_tag="ACL3JB_001161"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0685893.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            31723..32340
                     /gene="cysE"
                     /locus_tag="ACL3JB_001162"
     CDS             31723..32340
                     /gene="cysE"
                     /locus_tag="ACL3JB_001162"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0685894.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            32352..33236
                     /locus_tag="ACL3JB_001163"
     CDS             32352..33236
                     /locus_tag="ACL3JB_001163"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0685895.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            33318..34661
                     /gene="cysS"
                     /locus_tag="ACL3JB_001164"
     CDS             33318..34661
                     /gene="cysS"
                     /locus_tag="ACL3JB_001164"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0685896.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            34654..35040
                     /locus_tag="ACL3JB_001165"
     CDS             34654..35040
                     /locus_tag="ACL3JB_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0685897.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            35044..35928
                     /locus_tag="ACL3JB_001166"
     CDS             35044..35928
                     /locus_tag="ACL3JB_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0685898.1"
                     /translation="MREKELQDWFPDARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVTDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            36065..36664
                     /locus_tag="ACL3JB_001167"
     CDS             36065..36664
                     /locus_tag="ACL3JB_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685899.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            36807..36977
                     /locus_tag="ACL3JB_001168"
                     /pseudo
     CDS             36807..36977
                     /locus_tag="ACL3JB_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
BASE COUNT        11496 a         6541 c         8076 g        10879 t
ORIGIN      
        1 ctgttttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
       61 gaacatacaa tggaggtcgt catggacaat atcatcgatg tgtcaattcc tgttgcagaa
      121 gtggtggaca agcatccaga agtcttggaa attctagtgg agttgggttt taaacccctt
      181 gccaatccct taatgcgcaa tacagttggt cgtaaagtat cacttaaaca gggttctaag
      241 ctagcaggaa ctcctatgga caagattgta cgcacactgg aagcgaatgg ctacgaagtg
      301 attggattag actaatgaca gatgaacgga ttcatatcct acgggatatt ttgttagaat
      361 tgcacaatgg cgcctctcct gagtcggttc aagatcgctt tgatgcgacc tttacgggcg
      421 tgtcagccat cgagatttcc cttatggagc acgagctgat gaactcggat tcgggcgtca
      481 cttttgaaga tgttatggaa ctctgtgatg tccatgccaa tctttttaaa aatgctatca
      541 aaggtgtcga agtttcagat actgagcatc caggtcaccc agttcgtgtc ttcaaagaag
      601 aaaatctggc tctccgtgcg gccttgattc gcattcgtag attgttagat acctatgagt
      661 ctatggaaga cgaggaaatg ctggcggaga tgcgtaaggg tttggtgcgt cagatgggac
      721 ttgtgggtca atttgacatc cattaccaac gtaaggaaga actcttcttt cctatcatgg
      781 agcgctatgg acacgattca cctcccaaag ttatgtgggg agtggatgat cagattaggg
      841 aactctttca aacagctcta acgacagcca agtcactacc agaagtgtca attagcagtg
      901 taaaggaagc ttttgaagct tttgcgacag agtttgaaag tatgattttc aaggaagagt
      961 ccatcctgct catgattctc cttgagtctt ttactcagga tgactggctt cagattgcgg
     1021 aggagagtga tgcctatggc tatgccatca tccgtccgtc agagaaatgg gtgccagaac
     1081 gacagatctt tattgaggaa aagattgcag aggagcctgt acaactagat acggcagaag
     1141 gtcaagttca acaagtcata gatacgccag aaggccattt taccattacc tttaccccta
     1201 aggaaaagga agctgtgctg gaccgccata gtcaacaggc ttttggtaat ggctatcttt
     1261 cagtcgagca ggccaatctc atcctcaatc atctccctat ggagattacc tttgtcaata
     1321 aagaagatat tttccagtat tacaatgaca atacgccagc tgatgagatg attttcaaac
     1381 ggacgccgtc ccaagtcggg cgcaatgtcg aactctgtca tccgcctaag tatttggaca
     1441 aggtcaaggc tatcatgaag ggacttcgtg aggggaccaa ggacaagtat gaaatgtggt
     1501 tcaagtctga gtcgcgagga aagtttgtcc acatcaccta tgctgcagta cacgatgaaa
     1561 acggagaatt ccaaggtgta ctggaatacg ttcaggatat ccagccctac cgtgagattg
     1621 atacggacta tttccgtgga ttagaataag gagaaaaaat gagttacgaa caagaattta
     1681 tgaaggaatt tgaagcttgg gtcaataccc aaatcatgat taacgacatg gcgcacaagg
     1741 aaagtcaaaa agtttacgaa gaagaccagg acgagcgtgc caaagatgcc atgattcgct
     1801 acgagagtcg tttggatgct tatcagttct tgcttggtaa gtttgaaaac ttcaaagtag
     1861 gcaagggatt ccatgatttg ccagaaggct tgtttggtga gcgaaattat taaacgagaa
     1921 agattcttga tttttcacta aaatcttgat agaatgttta tgttaaatcc ttgtcagagc
     1981 agggattttt tattgaaagg attttatcat gtcaaagaaa ctcaatcgta aaaaacaatt
     2041 acgaaatggc ctccgtcgcg caggtgcctt ttcaagtact gtgactaagg ttgtagatga
     2101 gacaaaaaaa gtcgtgaagc gtgcagaaca gtcagcaagc gcagctggta aggctgtttc
     2161 taaaaaagtt gaacaagcag tagaagctac caaagagcaa gctcaaaaag tagctaattc
     2221 tgtagaagat tttgcagcaa acttgggtgg acttccactt gatcgtgcca agactttcta
     2281 tgatgaagga atcaagtctg cttcagattt caaaaactgg actgaaaaag aactccttga
     2341 cttgaaagga atcggcccag ctaccatcaa gaaattgaaa gaaaatggca tcaagttcaa
     2401 gtaatttttc ttgagccttg catttccgag aaaaacttgc tacaatagag ccattagagg
     2461 tgttttgaat cccacatttt acagaaagtg gcagcgctga gaagtccaca aatgtgtcaa
     2521 aactggttgc taatgactga aaaaatgaaa tatttctgtc tttttatttt aaagactaaa
     2581 gatgcgggct tggcccgaaa ttgggtggta ccgcggataa acacattcgt ccctgtcatg
     2641 tagatggcag ggcttttctt ttgtgtctta gtcaaaggag gttgttataa aacaatcatt
     2701 taaaactaat aaactatatt atggttttcc tgtttttatt ttaggatatc aagatcagaa
     2761 ttttagctat aacatcatga cctgtagttc ctcttatagt ctaggagatt gggttgtgat
     2821 tggagtcgtt gcgagagaga atgccgcaga gcagatcaaa caatatcaaa aatttactgt
     2881 gaatatttct gatgaaactt ctatgcttgc gatggagcag gctggtttta tcagtcatca
     2941 ggagaaattg gaacgtttgg gagtgcatta tgaaatttct gaacgaactc agactcctat
     3001 tttagacgcc tgtccacttg ttttagattg tcgggtagat aggattgttg aggaagacgg
     3061 tatttgccac atctttgcca agattcttga gcgacttgtt gccccagaac tcctggatga
     3121 aaagggacat tttaaaaatc aactgtttgc ccaacctatt tcatgggaga tggatatcag
     3181 cgcgtttatt gctatctgga caagcgtgta gatatgaagg gcagtttcat caaaaaagcg
     3241 agaaagaagg atggcaagaa ctgagctgcc agataaaatc gaaacagaac gtctcgtttt
     3301 acgagtccgc acagtggcgg atgctgagga tatccatgcc tatgctagtt tgccagaggt
     3361 cgcctaccca gcaggttttc tgcccgtcaa gaccttggaa gatgagattt actatctggt
     3421 gcatatcctt cccaatcgca atcaaaagga aaatttcccg gctggctacg gaattgtcgt
     3481 caaaggaacc gataaagtca ttggttctgt tgatttcaac catcgccatg aagatgatgt
     3541 gctggaaatc gactatacct tacacccaga ctattggggg cgaggttatg tgccagaagc
     3601 tgcgcgtacc ttgattgact tagcctttaa agatttgggt cttcacaaga ttgaactaac
     3661 ttgctttgga tataaccttc aaagtaaacg agtcgcggaa aagcttggct ttaccctcga
     3721 agctcgcata agagaccgca aagatgctca aggcaactgc tgtgatgatt taagatatgc
     3781 cttgctgaag agtgaatggg aggtgatttg atgcatcttt tcatcattgg tgctccagca
     3841 tcaggaaaaa tgaccattgg tcaagaatta tctcgactga cggatgctac cctattttat
     3901 aaccatcaag ccatcgattt tgcactagaa atctatcagg actatacaga ggaaatgtgg
     3961 gaatttgttc gtggaatcac tttttcattc cttggagcga gtgcaagaaa tcagcgatca
     4021 gtaattttaa cagatgtaat tgatttttca aatcagtatc acctgatata tttaaagcaa
     4081 attcagagtt tgttggatga ttatcatcaa gagattcttt ttgttgagtt ggaaacaagt
     4141 cttgaagagt gcatacgtcg aaatcgaacg gagaatcgat taaagtacaa acccttaaaa
     4201 cgacatattg aggtatctga aagagaaatt atagagaccg ctgaaacact tcaattaaat
     4261 tcccaacatc aaccgaatga gttgaaccac tactttaaaa taaataatac gaatttgtct
     4321 gcagaagaag ctgctaagca gattcaaaat aaaataaaca aaatagagaa aggacacaca
     4381 catgtctaaa gaactttcac ctaaatacaa tccagccgag gttgaggctg gtcgttacca
     4441 aaaatggctt gatgccgatg ttttcaagcc ttcaggcgat caaaaggcta agccttattc
     4501 aatcgtgatt ccaccaccaa acgtaactgg gaaactccac cttggtcacg cttgggatac
     4561 aactttgcaa gatattatca tccgtcaaaa acgcatgcaa ggttttgata ccctttggct
     4621 tcctgggatg gaccacgcag ggattgccac tcaggctaag gttgaggagc gcttgcgtgg
     4681 tgagggcatt tcccgctatg accttggtcg tgagtctttc ttgacgaaag tctgggaatg
     4741 gaaagacgaa tatgccacta ccatcaagga acaatggggc aagatggggc tctctgtaga
     4801 ctattctcgt gagcgtttca ctcttgacga aggtttgtca aaagctgttc gtaaggtctt
     4861 tgtgaacctt tacaagaaag gctggatcta ccgtggtgag tttatcatca actgggaccc
     4921 agcagctcgc acagcccttt ctgatattga ggtgattcac aaggatgtgg aaggtgcctt
     4981 ctaccacatg aattacatgc tggaagatgg ttcacgcgcc cttgaagttg ctacaactcg
     5041 tcctgagact atgtttgggg acgttgcggt tgcggttaat ccagaagacc cgcgctacaa
     5101 ggacttgatt ggtaaaaacg tcatccttcc aatcgctaat aaactcatcc caatcgttgg
     5161 agatgagcac gcagatcctg agtttggtac tggtgtcgtg aaaatcacac ctgcccacga
     5221 tccaaatgac ttcttggttg gccaacgtca taacttgcca caagtcaacg tcatgaacga
     5281 cgacggaact atgaatgagc ttgcctttga attttcaggc atggatcgtt ttgaagctcg
     5341 taaggcagtc gttgctaagt tggaagaaat cggtgccctc gtcaaaatcg aaaaacgtgt
     5401 ccacagtgtt ggtcactcag agcgtacagg tgttgtggtt gaacctcgct tgtctactca
     5461 atggttcgtc aagatggacc aattggctaa gaacgccatt gccaaccaag acacagagga
     5521 caaggtcgaa ttctacccac ctcgtttcaa cgataccttc cttcaatgga tggaaaatgt
     5581 ccacgactgg gttatctctc gtcagctctg gtggggtcac caaatccctg cctggtacaa
     5641 tgctgatggt gaaatgtatg tcggcgaaga agctccagaa ggtgacggat ggactcagga
     5701 cgaagacgtc ttggatactt ggttcagttc tgccctctgg ccattttcaa ccatgggctg
     5761 gcctgaagtc gactcagaag actttaaacg ttatttccca acttcaacct tggtaacagg
     5821 ttacgacatc atcttcttct gggtgtctcg tatgatcttc cagtccttgg aatttactgg
     5881 tcgtcagcca ttccaaaacg tgcttatcca cggtctcatc cgtgacgagc aaggacgcaa
     5941 gatgtctaaa tctctcggta acgggattga cccaatggat gtcatcgaga aatacggtgc
     6001 tgatgccctt cgttggttcc tttcaaacgg ttccgcacca ggtcaagacg ttcgtttctc
     6061 ttacgagaaa atggatgctt catggaactt tattaacaaa atttggaaca tttctcgcta
     6121 tatcctcatg aacaatgaag gtttgacgct ggatgtggcg catgacaatg tcacaaaagt
     6181 tgcaacaggt gaggctggta atgtgacgga ccgctggatt ctccacaatc tcaacgaaac
     6241 cattgcaaaa gttactgaaa actttgataa gttcgagttt ggtgtggctg gtcatatcct
     6301 ttacaacttc atctgggaag aatttgccaa ctggtatgtt gagttgacca aggaagttct
     6361 atacagcgac aatgaagacg ataaggtcat tactcgatct gttctcctct atacgctgga
     6421 caagatcctt cgtctccttc acccaatcat gccattcgtg acagaggaaa tctttggaca
     6481 aatctcagaa ggttctatcg tgacagctgc atacccaact gttaatctag cctttgaaga
     6541 ccttgcggct cacactggtg tggaaagtct caaagacttg attcgtgctg ttcggaatgc
     6601 gcgtgcggaa gtaaacgtag cacaaagcaa acctatcacc atccttgtta agacaagcga
     6661 tagcgacttg gaagccttct ttaacagcaa tgtcaactat atcaaacgct ttacaaatcc
     6721 agaacacttg gaaatcgcat caaccatccc tgcacctgaa ctggctatgt caagtgtcat
     6781 cacaggagca gaaatctacc tgccactggc cgatctcctc aatgtcgaag aagaattggc
     6841 acgtctggaa aaagaacttg ccaaatggca gaaagaactg gacatggttg gtaagaaact
     6901 ctctaacgaa cgcttcgtag tcaacgccaa accagaagtt gtccaaaaag aacgcgacaa
     6961 acaagctgac taccaagcca agtatgatgc gaccgtagca cgtattgatg agatgaagaa
     7021 gttggtgaaa tgatgttaaa aacctaaccc tatcgggttg ggttttacat ttgataatgt
     7081 tataataaaa aggagaaact ttaggagaat actatgggga aaattgttgc tattgattta
     7141 tttagcggtg caggtggcac tacaagtggc cttaaaaaat caggcataga tgttcaagtt
     7201 gctgttgaaa ttgattccgt agctgttaaa acttataagt taaataatcc tgaggtgtct
     7261 gtaatagata aagatataaa tgtagtatca ggagatgaag taaaagagta tcttaaaatt
     7321 gatacagacg ataaactaat gctcgtggca tgcccaccat gtcaaggttt ttcaactatt
     7381 ggtactaata atgaaaatga cgagaggaat caacttgttt ttcaatttct tcgtttgatt
     7441 aatgaattga atcctgattt tctattaatg gaaaatgttg tgggtatgac tagaacaaga
     7501 aatgaaaaaa tctttaaaaa atttttgaca tcaatcgata ataattatag tgttatttat
     7561 gacattttaa atacagctga ttatggagtt cctcaatcta gaaaaagatt ggtgttacac
     7621 ggaattagaa aagaaattct tgataacacg aatttaactt tgaatttgcc ttccaaaact
     7681 cattcaaata taccagaatt ggaccttctt tcatggatta atgcggatat aataatggac
     7741 ttgcctccta ttgaaggtgg tgaagaatat attggagaag gtatctacaa tcatgttgca
     7801 aacaaactat ctaatttaaa tattgagaga attactcata ttagaaataa tgggggaagt
     7861 agaacctctt tgccaaaatc tttagaatta aattgtcata aaaatcgttt aggtcatagt
     7921 gacgtatatg gaatattaga tatcaacaaa ccttccatta ctattacagg agggtgtatg
     7981 tcatattcaa aaggtagatt tgggcaccca actcaaaata gagctttaag tgcaagagaa
     8041 gctgcaagat tacagtcttt tgatgatgac tatatttttg ttggaaatag aggtcaatta
     8101 gctaagcaaa ttggtaatgc agttccagta aaattagctc aagctagtgg aaattatttt
     8161 atgtcagttt atagggagat agcaaatgga caatcagata attgagagtt tagaaggaat
     8221 aactaaaaat ttttttaaaa ataaaaatca attttatcct tatattgatt atatacgatt
     8281 tcctcattac aagagcttat cattaaattc aagaataaat tttaatttcc ctattacttt
     8341 attagttggt agaaatggag taaataaaac ttcaatttta caagctttat atggttctcc
     8401 agccaataaa agtgtgtctg aatattggtt tagtacaaat gttgatcaaa tagatgaagt
     8461 ggatgggaaa caatgtttaa tctattcata ttataacatt aaagcttcta gaaatgtaga
     8521 agttcttaaa ggccgttctg gaacaaaaaa aggattagat tattgggaac catatgctcc
     8581 tcaaaaacaa tatgagatgg aaagattacc caaaaataaa tatattggaa gttcttcgac
     8641 agacagatgg gatggcattg aaaaaaatgt tgtcttttgt gattgtaaag aatatgtttc
     8701 tgcttttgat ttatttttct atcactataa ttttaaaaaa atttctactc aacgtagtaa
     8761 acaagatttt ataagattac gatctaaacc agttgctgat attttaaaga ataatacaag
     8821 tagctatacg cgttataaaa aggaaatggt tatagataat gttaaagttg atgataaagt
     8881 ttgtgaaatt attagtgaaa taatggatga atcttataca gacattcaaa ttttaacaca
     8941 taagttgtat tcaaaaggtg atgatataaa agcttccaaa actatttgga tgaaaaaatc
     9001 tggaaaagaa tattccgagg cttttgcagg aacaggtgag gctagaatta ttttgttagt
     9061 aaatgatata gtaaatgcgc aatcaaattc attaatatta atagatgaac ctgaaatctc
     9121 acttcatccg agtgcaatct ataaatttaa agagttttta cttcaagagt gtttaaataa
     9181 aaaacatcaa attattatca ctacacattc tacacaactt ataaaagatt ttcctagaga
     9241 agccgtgaaa cttttagtga aaaacggaga aaaggtagat gttattgaaa atattgatta
     9301 tcaggatgca ttttttgaat taggtgatgt gtatcattct aggaagatga tttatgttga
     9361 agatagacta gctaaatata ttctagagtt tgttatcact cattcaggta gtgagaatct
     9421 taaacagaat ttagtagtga gatatattcc tggtggagca aatcaaataa tttgtaataa
     9481 tattttaaac tcatcgtatt tagattccga taaccattat ttttggcttg atggagatca
     9541 aaacactaat gttagtgaat caaataattt aatgaactat cttgaaaatg gtgttgttat
     9601 atcagataaa attcctgaat cagataataa aaatcttgat gatattataa aattgataac
     9661 gggatgtcca attaaattta atgtttcagg taataaaggg caaaaaaata atattgaatt
     9721 aattgcgaaa caaagaagct ttatagatta ttgggctaaa tacgtttctt atcttccttt
     9781 cccaacccca gagttttttt tagctaattt gtgtaacagc gtagataggg aaggttatga
     9841 tttttctaaa gatggcaacg gaaaagaata ttttagaaaa aaaactcaag tagcgttagg
     9901 aatagagaat ataacttctg aagatatttt ccaggagcaa agaagagctg tttcaaaaat
     9961 acagccagaa tcatcaatgt ttcagtgtat taaagaaaaa ttagaggcat tgttctaatt
    10021 ccttagatta ggtactacat aacaaatttt ttaaattcaa acccgcacca aaaacaacat
    10081 tgcaactttc ttctcaggta atgtgttggg atttgaacag accaacgagt tcatagtggt
    10141 gtatgccaat gactttgata agtctacgcg tcagacttat tagttcattt atccagatat
    10201 atctcgataa tcatattatt tagtcaaaga acatcccata tgagggcatg aaatgctaag
    10261 tttagcttgc tcactattaa gatgaagtat atatatttca tagaacctat tgtgaaggat
    10321 ttttataatt ttcgccaatt ccatacctat ttcacaattt accgatgaca cagaaaaaca
    10381 attgaaagga tatttctatg caatcaactt acaacattga caatccaaac ttgtcttatg
    10441 aagcgaagcg tgatttatgg cggataggtt ttggtctgca gaaagttgac aatctagtgc
    10501 catcagcgta tatggaatct ttggctgaga aacagtcccg gggtgaactg acttatgagc
    10561 aggtttatga ggatgcaacg gtttatcatc ataccgttga tgcgagtacg gaggaggcag
    10621 acttggtttc tttgcgtatc gtagaactct tgtctcgaag aggttttaga ttcagtcctg
    10681 cgactttact tgctattcat aaggagttgt ttcaagatat atttgaaccc tctattccgg
    10741 tggggcaatt tcgtcagacc aatatcacaa agaatgaacc tgttttgaat ggtgaaagtg
    10801 ttgtgtactc tgattactcc atgattcaaa tgaccttaga ttatgatttt aatcaggaaa
    10861 aacaagttgc atatgcgaca ctaactcagg cggatgtggt taaacaaatc cagcatttta
    10921 tttcaggaat ctggcagatt catccatttc gcgaaggaaa cactcggaca gtaacggtct
    10981 ttttgattca gtatcttcgt gagtttggtt ttgatattga taatacacca tttcagcaac
    11041 attccaaata ttttcgtgat gccttggtat tagataatgc aaagatttta cagcgacgtt
    11101 ctgagttttt aacagctttt tttgaaaatc tcttgctcgg tggtcaaaat gatttgtctt
    11161 cagaaaaaat gtatctagat ttagacctcg atttttcata atccaaatac tgagtaaaca
    11221 ttgaatttta ggcaaaaatg aagtaaatat tctcacaaga aaacgtatat catcaaagtt
    11281 ttaggtcgct tgataatatg cgttttttga attttataga ctgctcgttt aaactctatt
    11341 tacctcgtac attccggagc gagatggact attggtcgca tacaaaatga gtgttattcg
    11401 gattttattt tcgtgtacaa tttcagccat tcttgttata atcagcctat aggaatcaag
    11461 gaggtgattg ttatggctgt ttttgtgtct ttggatggaa ttgtggtaga agtacttgat
    11521 gtcttttctt cttttaatgg ggatagtgag tttttcttgt gtaaacgtct taaagacaag
    11581 agtcagtttg tgatggaacg ctctcggttc gaggagatgt tccaacttca aagtagtcac
    11641 ttgacgacgc aagaaaaatt acaattgttt acctccgtgt ttgctggacg ttatgatgtt
    11701 tatgctaaga attttatcaa tgaacaaggg aaaattcagt attttccttc ctatgattat
    11761 ggttggaagc agttgccacc tgaaaaacgg agtttccaga cattgacgaa ctccgttttg
    11821 aaatctcatt ttcgtgggga ggcagctatc ggtatctttc ctatgcactt agatgatagc
    11881 tgttattttt tggtactgga tttggatgaa ggagattgga aagaagctgg tttaaccatt
    11941 cgaagaatag ccagggaacg ccagatggaa gcccatttag agatttctcg ttcgggttac
    12001 ggactccata tttggttctt ctttgaggaa gcgattctga gtcgaaaggc tcgcctgttt
    12061 ggaaagaaac tattagaatt ggctatgcag gaaagtatgc aactgtcctt tgattctttt
    12121 gatcgcatgt ttccaaatca ggatgttctt cctaaaggtg gatttgataa tttaatttcc
    12181 cttccttttc aaggagaagc ttatcatcaa gggcgaacgg tctttgtgga tgaacagttt
    12241 cagccttatg aagatcaatg gaggtatcta caagaaattc agaggatttc aactgctaaa
    12301 gtggcactgt taatccaaga ggagttaggc aagcaagaat tggataagga gttgaaggtc
    12361 gttttatcca atatgatcca acttgaaaaa tcgtctgtga catccaaggc actttttttc
    12421 ttgaaaaata tggcttcctt ttctaatccc gaattttata gtagattgaa actagaatag
    12481 tacacctctg cttctaaaac attgttagaa atcgatttga ctttcctgat cgatttgtcc
    12541 tgttattatt tcattttact atatttaaag caggctatgc gacagccaat ctatcaaatt
    12601 cctgagcgaa tgtatttatt tggagaatcc gattattatt tatggctgcc aagaggcttg
    12661 ttagatccat tgcaagataa atttaagcag gtagttgtgg aggataggag aaaagtacaa
    12721 aggtctatta gagtagcatt taagggagag tttactttgg agcaagaatt agccctgtca
    12781 gatatgaatt ctaaagaaaa tggtttactt catgcgggac aggttttggg aagaccgttt
    12841 taggtgctgc tcttatctct gaacggaaaa caaaaacaat tattctagtc cataataagc
    12901 aactcttaga ccaatggcta gatcgcttaa actgcttttt gactttcgaa gaggaggagg
    12961 ctatccgtta tacggcatca ggtcgtgaaa aggtaatcgg ctatgttgga cagtacggtg
    13021 ggactaagaa atggctgagt aaactggttg atgtcgttat gattcaatct ctatttaagt
    13081 tggaaaatag tcaaagtctt ttggatgagt atgagatgat gattgtggat gagtgtcatc
    13141 atgtctctgc cttgatgttt gaaaaagttg ttgctcagtt tagagggaag tatctttacg
    13201 gtttgacggc tacgcctgag cgtaagaatg gtcatgagcc tattgttttt cagagaattg
    13261 gtgagatact ccatactgct gataagaggg aaacggattt taaacggcaa ttgcaattaa
    13321 gattcacttc ttttgctcat ttggaaattg aaaagaccaa agcaagtaat tttatacagc
    13381 tcagtgattg gattgctaca gactcagcga ggaatcagtt gattctcaag gatattctag
    13441 cccaagtggc agaaggtcgg aatatcttgg ttctagttaa tcgaattcaa cagatagatg
    13501 tttttgaaaa gttattgaaa gagaaagagg ttgatggctg ttacattatt agcggaaaaa
    13561 ccaaagtccg agagagaaca agtttactgg agatattaga acagctagat aaagggtttg
    13621 tattgttgtc aactggaaaa tacattggcg aaggttttga cttacctcag ttggacacgc
    13681 tgatcttggc agcgcccttt tcttggaaaa ataatttgat tcagtacgcc ggtcggattc
    13741 atagaaacta caaagataag tctttggtac gtattttcga ttatgtggat attcatgttc
    13801 cttatttaga aaagatgttt cagaaacgac aagtagctta tcgaaagatg gattatcgtg
    13861 ccattgaggg tgaggagaaa caattcgttt atgttgatag tagatatgag aatgtgttga
    13921 ggaaggactt agcaggggaa agacaggaat gtctgcttgt tttaccttat gtgcaccaga
    13981 caaaactgat gaattttcta aaagaattta ggattagtca aattgagata tgtataccag
    14041 agacggttgc aaataaagca tggctagacc agttgaagag caagaaaatt aaagtgtctt
    14101 ttactcaatc aaaaatagta acgcctattc ttttggtgaa taagactatt gtttggtatg
    14161 gtgcaatgcc attattaggg aaggtagatg agatgaccat attacgtttg gaatcagcta
    14221 gtatagtttc tgaactagtg gcaggtttac gatagagaaa atttttaaaa atttctatgt
    14281 atgattttca tttttttagt gagactgttg ccattatcac attcgaatca cacaaaataa
    14341 aaaaatttct acaagtactt gacaaataga ttgaaatatc ttaaaatgaa aatggttaca
    14401 gagttattaa ttatttaagc ttcatgtcac cattaaaaat tgaaataaaa ggatgttatc
    14461 actaatacaa gtgagcagga acctatttaa tcacatcgga agaagtttct tgatgttttt
    14521 aagtaggttc cttttatttt aaaagggaaa ttttatgatc ataaaacgaa tactaaacca
    14581 caatgccgta attgcgcaaa gtaaaaaaga tatcgatatt cttctttttg gaaggggaat
    14641 agcttttgga agaaaaactg gagataaagt aaatccaatt gatattgaga aaagtttttt
    14701 tctcaaaaat agagataata tgacccgttt tacagagatg tttattaacg ttcctttgga
    14761 gttggtgtac atcaccgaaa aaataattaa cctaggtaaa ataacattgg gtaataattt
    14821 tgatgaaatt atctatatta atttaacgga tcatatttct tcgagcatag aacgttataa
    14881 agaagggatt attatttcga atcccctacg ctgggaaata tcgaaatatt ataaagaaga
    14941 atttgaactt gggaaaaggg ctttacaaat aataaaaaaa gagttaggta ttgaacttcc
    15001 aattgatgaa gctgcattca tagcgctaca ttttgttaat gctaatttag aaaataattt
    15061 tcaagagtcg tataaaatca ctgaaataat tatgggaatt gagaaaatca ttcaagattt
    15121 ctattgtact gagtttaacc aagattctat tgattattat agattcataa ctcatataaa
    15181 attatttgcc catcgtttgg ttgaaaatac aacttattgt gacgatgatg atgaagactt
    15241 gttagcatta atgaaaaata aatatcctag agaatatgaa tgtggtgaac aggtggcaat
    15301 gtttatacaa acggagtaca attatttgct gacttctagt gaattagttt atttgatggc
    15361 tcatattcgt cgcttaacaa aaaatttaga ttaatagaat aggagaatac catgagttat
    15421 aaagatacgg tacaaaaaat cctcgatgta attggaggcg aaaaaaatgt caatagagtt
    15481 acccattgtg taacacgttt aagattagaa ttaaaagatg aaaatttagt caatgatgat
    15541 gatgtgaaga agataccagg tgtaataggt attatgaaaa agaatggaca atatcaaatt
    15601 atacttggta atgatgtagc taattattat aaagaattcg ttaaacttgg caattttgaa
    15661 tccgattcag ttgttcaagg gcacaaaggg aatattttag aaagaatcat tgagtatatc
    15721 gctggttcca tgactccaat cattccagca atgttagggg gaggtatgct gaaagtcttg
    15781 gtaattattt taccaatgct tggtatattg caatcagatt ctcagactat tgcttttttg
    15841 acattttttg gggatgctcc atattatttc ttaccgctgt tattagctta ttctgcatca
    15901 caaaaattaa aagtaacatc tacattagct atgtctgtag caggtgtact tctccatcca
    15961 aattttgttc aaatggtgca atcagggaat cctcttagtt tatttgttgt acctgtgaca
    16021 ccagctagtt atggttcgtc agtcgttcca attcttatta tggtttggtt gatgaaatat
    16081 attgaaaaaa tgattgctaa attaacacca gctgttacta agagtttttt gcaacctacg
    16141 ctagtattat tagtatcaag ctgtattgcc ttagttgtag tcggacctat tggagtaatt
    16201 gttggtgaag gattatcaaa tctagttggg caaatgtatg gtgtagctgg atggcttaca
    16261 ttagctattc ttggcgctat tatgccattt attgttatga ctggaatgca ttgggctttt
    16321 gcacctattt ttttggcggc atctattgct actccagacg tattaattct tccagcaatg
    16381 ttagggtcaa acttagctca aggggctgct tcgatggctg ttgcattaaa gagtaaaaat
    16441 aataatacaa aacaaattgc ttttgcagca ggtttctcag ccttacttgc agggattacc
    16501 gaacctgcat tatatggtgt gactttaaaa tataaaaaac cgctttatgc agctatgatt
    16561 ggtggtggat tagcgggatt atttgcaggt cttactagtg ttaaagcgta tctatttgct
    16621 gtcccatctt tgatagcgtt gcctcaattt atttattctg atgtgccatc aaatattgta
    16681 aatgctttaa ttgtggcggt catttcggtt gttattacct ttgtattagc ttatatattt
    16741 ggaatcgatg aagaagagag ttctagcaat ttagaagtta aagctggagt ttcaaataaa
    16801 aaaatgatat tttctcctat atcaggagaa atcattccgt taagcgatgt ccaggataaa
    16861 acattttcag ataaactaat tggagacgga gtagcgatta tcccaagtga aggtaaggtt
    16921 tatgcaccat ttgatgggaa aattacaaat atttttccga ctaagcacgc aattggattg
    16981 aagagtgatg agggtgttga gttactaatt catattggat tagatactgt tgagctaaaa
    17041 ggtcaaggtt ttattagtca tgtagaagaa ggagacagag ttttcaaaaa tcagttgatt
    17101 tttgaaatgg acttgaattt aatcaagact aaaggctacg aaacagttac accggtaatt
    17161 gtaacgaata ccaatgattt tctagatgta ttagtattac ctaataatca gacaatcgag
    17221 cattctaagg aattactggt aatattataa tggaggaaag ttatgaccat ttttccagat
    17281 gattttcttt ggggtggagc tgttgcagct aatcaagtag agggagcata taatgaagat
    17341 ggtaagggct tatcagttca ggatgtgtta cccaaaggtg gattaggaga agcaacagaa
    17401 aatcctacag aagataactt aaaattgata ggtattgatt tttatcataa atataaggaa
    17461 gatataacct tgttttctga aatgggcttt aatgtttttc gtacttctat tgcatggagt
    17521 agaatttttc caaaaggaga tgaggaagaa cctaacgaag ctgggttgaa atattatgat
    17581 gaattgtttg atgaactaca tgctcacggg atagaaccac ttgtaactct ttcacactat
    17641 gagactccat tatatttagc aagaaaatat catggatggg ttgataggag aatgattcat
    17701 ttttatgaaa aatttgctcg aacagtttta gaaaggtata aagataaagt taaatattgg
    17761 cttacattta acgaagtaaa ctctgttttg gaattaccat ttactagtgg aggaatagat
    17821 atacctaagg agaatctttc gaaacaagaa ttatatcaag ctatacatca tgaattagtc
    17881 gcctcgagtt tggttacaaa aattgctcgt gagattaatt cagagtttaa ggtggggtgt
    17941 atggtattag ctatgccagc ttatccaatg actccaaatc caaaagatgt atgggcgact
    18001 catgagtatg agaatctaaa ttatctattt tcagatgtgc atgttagagg ttattatccg
    18061 aattatgcaa aaagatattt taaggaacat gacattaaca tagagtttgc agctgaagat
    18121 gcagagttat taaaaaatta tactgtagat tttttatcct ttagctatta catgagtgtg
    18181 actcaatctg ctcttccaac acagtataat tcaggagaag ggaatattat tggtggttta
    18241 gtaaatcctt atttagagtc ttctgagtgg ggatggcaaa ttgatccaat tggactacgt
    18301 ataattttaa atagatatta tgaccgttat caaatcccat tatttatagt agaaaatgga
    18361 ttaggtgcta aagatcaact aataaaagat gaacttaata acttaaccgt ccaagatgat
    18421 tatagaattc agtatatgaa agaacattta ttgcaagttg ctgaagctct acaggatggt
    18481 gttgaaatta tgggctatac gtcttgggga tgtattgact gtgtttctat gtccactgca
    18541 cagctttcta agaggtacgg tctcatttat gttgatcgaa atgatgatgg aaatggcaca
    18601 ttcaatcgat ataagaaaat gtcctttact tggtataaag gagtgattga atcaaatgga
    18661 gaatccttat tcaaatagtt ttttattgat gactagctat tatcacggtt aaggtggcat
    18721 ttcattaaat atgaaataaa gaggtttgga agacatcaaa ttctaaacct ctttatttta
    18781 tagggggatt aattaattta attttgttac agagagccga ttataaatag ttaacttagg
    18841 atagattggt tatatatagt agactgaatc taaaatagta cgaaataatt gctaaaacat
    18901 ttatagaaat taattttact ttcccaatcg atttgttttc atcttatttc aatccgctat
    18961 aaagttagat aagaataagc tgacaagcag aagtaagata ggtcttgcaa gaatggtaaa
    19021 aatctgataa actaagtagt aattgaatag gaatctgaaa gactagtagc ccaagggaag
    19081 tatatcaggg aggagagccg tgactgcaag ctctctatat gaaagctggg tgaattcact
    19141 tgcgcatgga tttagaaatg aaggtctgac ttgtcagatg aaaacggatg gtaccgcgtg
    19201 tcaacgctcc gagtggagtt tttggcatgt ggttttcttt ttatctacga gagactgatg
    19261 gaggaaatat gtcaactatt gaagaacaat taaaagcgct tcgcgaagaa acgctggcta
    19321 gcttgaagca gattactgct ggaaatgaaa aagagatgca agatttgcgt gtctctgtcc
    19381 ttggtaaaaa gggttcgctc actgaaatcc tcaaagggat gaaagatgtt tctgctgaga
    19441 tgcgtccaat catcgggaaa cacgtcaatg aagctcgtga tgtcttgact gctgcttttg
    19501 aagaaacagc taagctcttg gaagaaaaga aagtcgcggc tcaactggct agcgagagta
    19561 tcgatgtgac gcttccaggt cgtccagttg cgactggtca ccgtcacgtt ttgacacaaa
    19621 ccagtgaaga aatcgaagat atcttcatcg gtatgggtta tcaagtcgtg gatggttttg
    19681 aagtggagca agactactat aactttgaac gtatgaacct tccaaaagac cacccagctc
    19741 gtgatatgca ggatactttc tatatcactg aagaaatctt gctccgtacc cacacgtctc
    19801 cagttcaggc gcgtgctatg gatgcccatg atttttctaa aggtcctttg aagatgatct
    19861 cgccagggcg tgtcttccgt cgcgatacgg acgatgcgac ccacagtcac caattccacc
    19921 aaatcgaagg cttggtagtt gggaaaaata tctctatggc tgatcttcaa ggaacgcttc
    19981 agttgattgt ccaaaaaatg tttggtgaag agcgtcaaat tcgtttgcgt ccatcttact
    20041 tcccattcac agagccatct gttgaggtgg atgtttcttg cttcaagtgt ggtggagaag
    20101 gctgtaatgt atgtaagaaa acaggttgga tcgaaattat gggggccggt atggttcacc
    20161 cacgtgtcct tgaaatgagt ggtatcgatg cgactgtata ctctggcttt gcctttggtc
    20221 ttggacaaga gcgtgtagct atgctccgtt atggaatcaa cgatatccgt ggattctacc
    20281 aaggagatgt ccgcttctca gaacagttta aataatgatt agaaaagtag aaatggcaga
    20341 tgttgaggtg ttggctaaaa ttgccaaaca aacctttcgt gaaacctttg cgtatgataa
    20401 tacggaagag cagttacagg aatactttga agaggcttat agtctgaaaa ctgtgtcaac
    20461 tgagttggga aatcctgact ctgaaaccta tttcattatg catgaggagg agatagctgg
    20521 ttttctcaaa gtcaactggg gaagtgctca aactgagaga gaattagagg acgcttttga
    20581 aattcaacgc ctctatgtgc tacaaaaatt ccaaggattt ggactaggta agcaactgtt
    20641 tgaattcgca cttgaacttg ctacaaaaaa tagtttttct tgggcttggt taggtgtttg
    20701 ggagcataat acaaaagctc aagcgtttta taatcgatat ggttttgaaa aatttagcca
    20761 acatcatttt atggttggtc aaaaagtaga tacggattgg ttactgagaa agaaattaag
    20821 gtaagaagag gattcttcta ttgaaatgat aggaaaggaa aagaactaga gtgacaactg
    20881 tcattctgga gaactaaatt atgcttgtat cttataaatg gttaaaagaa ttggtggaca
    20941 ttgatgtgcc atcacaggag ttggctgaaa aaatgtcaac cacagggatc gaggtagaga
    21001 gtgtcgaatc accagctgct gatctctcaa aaattgttgt cggtgaggtc ttgtcttgcg
    21061 aagatgtgcc agagactcac ctccatgttt gtcaggttaa cgttggcgaa gaagaagccc
    21121 gtcagatcgt ttgtggtgcc ccaaatgtgc gtgctgggat caaggtcatg gtggctcttc
    21181 caggagctcg tatcgctgat aactacaaaa tcaaaaaagg aaaaatccgt ggtttggagt
    21241 cacttggaat gatctgttca cttggtgaat tggggatttc tgactcagtt gtgcctaagg
    21301 aattcgcaga tggcatccaa atcttgcctg aggatgccgt gccaggtgag gaagtctttt
    21361 cttacctaga cttggatgat gaaatcatcg aactttccat cacaccaaac cgtgcagatg
    21421 ccctttctat gtgtggagtg gctcacgaag tggcagccat ctatgacaag gcagtcaact
    21481 ttaaagaatt tactctaaca gaaactaatg aagctgcggc agatgccctt tctgtcatca
    21541 ttgagacaga caaggcgcct tactatgcag ctcgtatctt ggacaatgtg accatcgcac
    21601 caagtccaca atggttgcaa aaccttctca tgaacgaagg aatccgtccc atcaataacg
    21661 tagtggacgt gaccaactac atcctgctct attttggtca accaatgcat gcctttgact
    21721 tggataactt tgaagggact gacatccgtg tgcgtgaagc gcgtgctggt gaaaaattgg
    21781 tgaccttgga cggtgaagaa cgtgacttgg acgtgaatga cctagtcatc actgtcgcag
    21841 acaagccagt agcccttgca ggtgtcatgg gtggtcaagc aacagaaatc tctgaaaaat
    21901 ctagtcgtgt tgtccttgaa gctgctgttt tcaatggcaa atctatccgt aagacaagtg
    21961 gtcgcctgaa ccttcgttct gagtcatctt ctcgctttga aaaaggaatt aatgtggcaa
    22021 cagttaatga agcccttgat gcggcagcta gcctgattgc ggaacttgca ggtgcgacgg
    22081 tgcgtaaggg catcgtttca gcgggtgagc ttgatacttc agatgtagaa gtttcttcaa
    22141 cccttgctga tgttaaccgt gtcctcggaa ctgagctgtc ttatgctgat gtagaagacg
    22201 tcttccgtcg tcttggcttt ggtctttctg gaaatgcaga cagctttaca gtcagagtcc
    22261 cacgtcgtcg ttgggatatc acaatcgaag ctgatctctt tgaagaaatc gctcgtatct
    22321 atggatatga tcgcttgcca accagccttc caaaagacga tggtacagct ggtgaattga
    22381 ctgtgacaca aaaactccgc cgtcaagttc gtaccattgc tgaaggagca ggtttgacag
    22441 aaattatcac ctatgctctg acaactcctg aaaaagcagt tgagttcaca gctcaaccaa
    22501 gtaaccttac tgaactcatg tggccaatga ctgtggatcg ttcagtcctc cgtcaaaata
    22561 tgatttcagg gatccttgat accgttgcct acaacgtggc tcgtaagaat aaaaacttgg
    22621 ccctttatga gattggaaaa gtctttgaac aaacaggtaa tccaaaagaa gaacttccaa
    22681 atgagatcaa cagctttgcc tttgccttga caggcttggt tgctgaaaaa gatttccaaa
    22741 cagcagcagt tccagttgat ttcttctatg ctaagggaat ccttgaagcc ctatttactc
    22801 gtttgggact ccaagtaacc tatacagcaa catctgaaat cgctagcctt catccaggtc
    22861 gtacagccgt gatttcactc ggtgaccaag ttcttggttt ccttggccaa gtgcatccag
    22921 tcactgccaa ggcttacgat attccagaaa cgtatgtagc tgagcttaac ctttcagcca
    22981 tcgaaggggc gctccaacct gctgttccat ttgtggaaat caccaaattc ccagcagtca
    23041 gccgtgacgt tgcccttctc ctcaaggcag aagtgactca ccaagaagtt gtagatgcta
    23101 tccaagctgc cggcgtgaaa cgtttgacag atatcaaact ctttgacgtc ttctcaggtg
    23161 aaaaactggg acttggtatg aagtcaatgg cttatagctt gaccttccaa aatccagaag
    23221 acagcttaac ggacgaagaa gtcgcacgct acatggaaaa aatccaagcg tctctcgaag
    23281 aaaaagtcaa tgcagaagtg cgttaaacga tagtaggata caaattcccc ctctagttta
    23341 tgaacactag aggggtgatt ttatataaaa taattaaaat gtgatttctg taaaaataca
    23401 tctatgatca gagttttgaa aacttacaat gtctaaatct ttaacatagt agtggttttt
    23461 aggcaataaa atatgatcta ttgttgcatt aaaaagtttt ggactttggc tattccaagt
    23521 tcctctttca aaaggtggaa gtgcattcaa tgcgtcccta tgagagctta tttttgcaag
    23581 tgctccatga cgcatagttg cattaaaatc acctgcaata atagcctttg gatattttga
    23641 agccaattga ttatgaatga tgtttaagtc ttgcttccag atttccatta aacctggcag
    23701 aggaggagca gtatgcaagg caatgatatc tggtatattt tgttttctcg aatgtaatac
    23761 aattgtcccg aaccgtgttg tatgaaaagt tttagcttct gtatagaaac cataactttt
    23821 cttgacaatc acagtcacag gagctattcc actattggta ggtggagaag tgaaaatatc
    23881 atagttggcc atagaaagtc caacttgatg aaacaatagt ttgattctct ggttttcttg
    23941 ctcacctctg atattggtag ctagttcagg gaatatagcc atatcggcgt caaaatggct
    24001 aaaaattcgc tcaatatgtt gtgcttctat ttgattagcg acgttccaag ttactaattt
    24061 taaggtttta gtcttatttg atgcagaaga aagggtttta tctgttccga ataatagtaa
    24121 tatgagcgat agtaagagca aaatgccaga gtaaaaccgt atttgtttat ttttcttgta
    24181 aaaagatagg aaaaaaataa gaaacttaaa atagcagcca tagttgcagt agctaagggg
    24241 aaggcataaa tctgtgccaa gataggttgg gtagatagcc aaatgttaag attagaagat
    24301 gggaaaaaag aataagttat gatagggata gaaaagagaa tgaccgaaag ggcagagaga
    24361 aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg ttgctcggag ctaatgtgac
    24421 tttgtgactt tacttgattg atattctttt tattgtcttc cttatagatt aagtacaacc
    24481 caagtaaaaa aagtccaatt taagattgaa atgattaaaa ggcacagaga tgcaagacaa
    24541 ttatactaca aaaggtaaac atttgacaat cgatagccgt cgcttaatcg aaagatggaa
    24601 aaaagaagga aaatcaaata gagaagttgc ctctctactt ggaaaagctc ctcaaactat
    24661 ccacactgaa atcaagcgtg ggacagtccg aaaatgtctt ggaaaagggc gcttcaaaga
    24721 ggtttattct gccgactacg ctcaacagtc ttatgaaaac aatcgcaagc gctcggtcaa
    24781 gaaatcaagc ttgaccaagg aactaaagga aaagattctc cactatacat aaccaaaaat
    24841 tttcgcctga aatgatggtt atggctaaag gggttaacgt gggaatttca accatttact
    24901 attggattca tcgtggaaaa ttggggttaa gcaaacagga tttgctttat cctagaaaag
    24961 gaaaatctgt taagaaacaa gttagtccca attttaaacc cgctgatcaa tctatcgaat
    25021 cataattcgc tcattttttc aaaaaataca tagatctaaa agaaagaggg gtaagtgatg
    25081 aagaatagtg ctattgggag taattggaag gatgtctatc tgagctcttt agcaaggagg
    25141 aaatccttga aagtgatatg cgagtagcta tcatgagcga gttgattgaa gccagaaata
    25201 agcaaggaat cagtcagaaa aagctagagg aagtcagtgg agtgagtcag cctgttatag
    25261 ctaggatgga gacaggtaag actagtccac agttggacac agtcttaaaa gtcctagcta
    25321 gtctaggaaa gacactagca gtcgttccac ttgaacaggg gaaaagttga ctagaatcag
    25381 ttatagtctt ttctaataac aagccatagt cacttataag aattactaat aacgcgtttg
    25441 agcattctaa ctaaaataca gctaaaaaca agttataaaa gggatttgag acgtttgctt
    25501 caagtctttt tcttttgtcc gaaacagata tatagtttca aactatatca aaccctaatt
    25561 ttttacaatt atacagacgc tttcttttct gttaagatag tttcaacaac aaattttgga
    25621 ggacacatca tgtcaactac aatcgtcggt ttccctcgtt tgggcgaatt ccgtgaatta
    25681 aaatttacaa ctgaaaaata ctttagaaaa gaaatctcag aagaagaact tttagcagca
    25741 gcaaaagact tgcgtgctaa acactggaac attgtcaaag aaaaaggcat cactgaaatt
    25801 ccatcaaatg acttttctca ctatgataac ttcctagatg cggctttcct tttcaacgtg
    25861 gtgcctgcat ccgttcaaaa cttggacttg tctgaccttg agcgctactt cgctttggga
    25921 cgtggttacc agggagaaaa aggggacgtt cgcgcccttc caatgaagaa atggttcaac
    25981 actaactacc actacatcgt tcctaaattt gaaaaagaca ctcaagtaaa attggctggt
    26041 cacaagattt tcgatgagtt ccaagaagcc aaagaacttg gattgaacac tcgtcctgtt
    26101 cttgtaggtc ccttcacttt ccttcaattg tcagactttg aagaaggcgt gaaagcagac
    26161 gacttcgtag atagcttagt gtctgcttac caagaagttt ttgctaaatt ggctgaactt
    26221 ggtgcgactc gcatccaatt ggatgaagcg gctcttgtaa aagacttgac agctgaagaa
    26281 aaagctcttt tcttgaacct ttacaacaaa ctcttggctg acaaaaaagg tcttgaagtc
    26341 ttgcttcaaa cttatttcgg tgatgttcgt gacgtatacg ctgaccttgt aaacttacca
    26401 gtagatgcta tcggtcttga ctttgttgaa ggtaagaaaa ctcttgaact cgttaaaggt
    26461 ggcttcccag ctgacaagac tctctatgta ggtattgtca atggtaaaaa catctggcgc
    26521 aacaactacg aaaagagctt gactgttctt gagcaaatcc cagctgaaaa catcgttttg
    26581 acaagctctt gctcacttct tcatgtgcca tttacaactg ctaatgaaga atttgaacca
    26641 gcactcttga accactttgc ctttgcagtt gaaaaattgg atgaaatccg tgacttggat
    26701 gctatccgaa atggtcaagg ttcagaagct cttgcagcca acaaagaact ctttgcgact
    26761 gagcgtgttg gtgaaaatgc tgaacttcgt gcgcgtatcg ctggcttgac agacgcagac
    26821 tacactcgtt tgccagcctt tgcagaacgt gaagctatcc aagaagaagc tttcaaactt
    26881 ccagctcttc caacaacaac gattggttca ttccctcaaa caaaagaagt tcgtgccaaa
    26941 cgtttggctt accgtaaagg tgaattgtct caaaaagagt acgacgcttt ccttgctgaa
    27001 acgattgacg aatggatcaa gtggcaagaa gatattgact ttgatgtcct tgttcacggt
    27061 gaatttgagc gtaatgacat ggttgagtac ttcggtcaaa acttgtcagg atacctcttc
    27121 tctaaaaatg gatgggtaca atcatacggt atgcgtgggg taaaaccacc aatcatctgg
    27181 ggtgatgtca ctcgtcttaa ccctatcact gttaaatggt ctagctatgc acaaagtcgt
    27241 acaaacaaac ctgttaaagg tatgttgact ggacctgtta ccatccttaa ctggtcattc
    27301 ccacgtgaag acatctctat caaggattca actctccaaa tcgcccttgc tatcaaggat
    27361 gaagtacttg accttgaagc tgctggtgtg aaaatcatcc aaatcgacga ggctgctctt
    27421 cgtgaaaaat tgccactccg ccgtagcgac tggtacgaag actaccttga ctgggctatt
    27481 cctgccttcc gcttggtaca ctcaacagta gcgccagaca cacaaatcca cactcacatg
    27541 tgttactcag aatttacaga tatcatccca gctatcgata acatggatgc agacgttatt
    27601 tcctttgaag ctagccgttc aaaccttgaa atcttggacg aactcaaagc gaaaaacttc
    27661 caaacagaag tgggacctgg ggtttacgat atccactcac ctcgtgtacc aaatgaaggc
    27721 gaaatcgaca acacaatcga agtcatcctt gctaaagtgc caagcaagaa agtttggatc
    27781 aaccctgact gtggtttgaa aacacgtggt atcccagaaa caaaagaaag cttgatccgc
    27841 cttgttgaag cagctaaagc tgcgcgtgag aaattgtaag attggatttc tctccataca
    27901 gtggttgttc aaaaagaaat caactagaaa aggttattac atatgtcacg ccaaacaccg
    27961 tcactctcat ttgaagtgtt ccctccaaac ccagccgtgg gtaatgataa cattatttca
    28021 gccttgcagg atatgcagga gttggctccc cattttatca gtgtaactgc cagcaataat
    28081 aaatttaata tcaaggaaac gacggttcgt ttggctgact ttatccaaaa tgatttggcg
    28141 attccgacca ttgcccactt gccagctatt tatctaacta aggacaaggt tgctgaaact
    28201 attgctgact tggacaaagt tggggtgcag aaaatcttgg ctcttcgtgg ggatattatt
    28261 ccagacgtgg aaccacaaaa ggatttccgc tatgcaaccg acttgattga gcttatcaag
    28321 gaacgagccc ctcactttga tattattgga gcttgctatc cagaagggca tccagattcg
    28381 ccaaatcaga tttcagatat tcaaaatctt aagaagaaag tggatgcagg ctgttcgagc
    28441 ctcgtaactc agctcttctt tgacaatgag cgcttctatg attttcagga caagtgcatc
    28501 ttggctggga ttgatgttcc cattcatgca ggaattatgc caattctgaa tcgaaatcag
    28561 gctctccgac tcttgaagac ttgtgagaat atccatcttc cacgcaaatt taaagccatc
    28621 ttagacaagt atgagcatga ccctgagtcg ctcagagcag caggacttgc ctatgcagtg
    28681 gaccaaatcg tggacttggt aactcaggat attgccggtg tgcatctcta tacgatgaat
    28741 aatgctgata cagcaaaata catccatcaa gcaacccatg ccttgtttaa tcaccagtct
    28801 ctaggataat aaaagcaaac cattcttctc aggtgagggg aatggttcct ttttaatggt
    28861 aaagacctca ctttttaaga aaaatatgat aaaataaatt ctgtacgtac ttgatacaaa
    28921 gatgaaggta ttaaataata caatgcattt aaactgtaag atttaacgac acgagtgagt
    28981 caaatcgatg ttatttgacg agagagttag taaagcattt agctaatcgc ccgatagcga
    29041 ttagcgtgaa agctttagat actttagtat taaacctttc taatgatgta tcttgaaaac
    29101 tgaacttgcc tacaactctg tggaaaaaga taaatctccc taggagcagt cgctccgtcg
    29161 ttcgatttcc tattttcctt tgagttgctt gacggcttag tatcttgagt aattgaattt
    29221 tggtctcatt tcttaggaaa aaagataagc ttcctagcac tcgtcgagtg cgacgtcacc
    29281 ttcctatttt tctacagaaa tgttcggcaa gccgaaccgt ccaaaatatc ttgtgtaatt
    29341 gaacacggcc gaaaagctgt gtaaaaaaga taaactgtct tgtcttcatc gaagacttcg
    29401 tcagtttcct atttttactt tgcttttgac gtccttggta tcttgatctt tgtaggcaag
    29461 gcgtataatt tcatcaatcc aaaggggatt aaaatggcaa aacaagtgtt tcaaacgact
    29521 tttgcgggtc gtgagttaat tgtagagact ggtcaggttg ctaagcaagc aaatggatct
    29581 gttgtcgtac gttacggtga gtcaactgtc ttgactgctg ccgttatgtc taagaaaatg
    29641 gcaactgggg atttcttccc actccaagtc aactacgaag aaaaaatgta tgcggctggg
    29701 aagtttcctg gtggctttat gaaacgtgaa ggacgtcctt caacagatgc gaccttgaca
    29761 gcgcgtttga ttgaccgtcc gattcgtcct atgtttgcgg aaggtttccg taatgaagtc
    29821 caagtcatca atacagtgct ttcttatgat gaaaatgcat ctgcaccaat ggctgctatg
    29881 tttggttcat ctttggcact gtctatttca gatattccat ttgacggacc aattgctggg
    29941 gtacaagtgg gatatgtaga tggccaaatc atcatcaacc caagtcaaga acaagcagag
    30001 caatctcttc ttgaattgac agtagctgga accaagcacg ctatcaacat ggtagagtct
    30061 ggtgccaaag aattgtcaga agaaatcatg ttggaagcgc ttcttaaagg gcacgaagct
    30121 gtcaaagaat tgattgcctt ccaagaagaa atcgttgctg ctgtcggtaa agaaaaagca
    30181 gaagtggaat tgcttcacgt ggatgctgaa ttgcaagctg aaatcattgc agcctacaac
    30241 agtgacctcc aaaaggcagt tcaagtagaa gagaaattgg cccgtgaagc tgcgactcaa
    30301 gtagtgaaag accaagtgac tgccgtttac gaagaaaaat atgcggacca cgaagaattt
    30361 gaccgtatta tgcgtgatgt ggctgaaatc ttggaacaaa tggaacacgc agaagtgcga
    30421 cgtttaatta cagaagacaa ggtgcgtcct gatggtcgta aggtcgatga aatccgtcct
    30481 ttggatgcgg ttgttgactt ccttcctcgt gtacatggtt caggtctctt tactcgtggg
    30541 caaactcaag ctctttcagt cttgaccttg gctccgatgg gagaaactca aatcattgat
    30601 ggtttggatc cagagtacaa gaaacgcttt atgcaccact ataacttccc tcaatattct
    30661 gtaggggaaa caggtcgtta cggtgcgcca ggtcgtcgtg aaatcggtca cggtgccctt
    30721 ggtgagcgtg ctcttgctca agtcttgcca agcttggaag aattcccata cgctatccgt
    30781 ctagtagcag aagttttgga atcaaacggt tcttcatctc aagcttctat ctgtgcggga
    30841 actcttgccc ttatggctgg tggtgtgcca atcaaggcgc cagtagctgg tattgctatg
    30901 ggacttatct cagatggaaa taactacaca gtattgacag atatccaagg tttggaagat
    30961 cactttggag atatggactt caaggttgca ggtactcgtg atgggattac agcccttcaa
    31021 atggatatca agattcaagg gattactgca gaaatcttga cggaggctct tgctcaagcc
    31081 aagaaagcgc gttttgaaat ccttgatgtc attgaagcaa ccattccaga agttcgtcca
    31141 gaattggctc caactgctcc gaaaattgat acgatcaaga ttgatgtgga caagattaag
    31201 attgtcatcg gtaagggtgg agaaaccatc gacaagatta tcgctgaaac aggtgttaag
    31261 attgatatag acgaagaagg aaatgtgtct atctactcta gtgaccaaga tgctattaac
    31321 cgtgccaaag aaattattgc tggtttggtt cgtgaagcca aagtggatga agtttaccgt
    31381 gctaaagtcg ttcgtatcga gaaatttggt gcctttgtta acctctttga taagacagat
    31441 gcccttgttc atatctctga gatggcttgg actcgtacca atcgtgtaga ggatttggta
    31501 gaaatcgggg atgaagttga tgttaaggtt atcaaaattg atgaaaaagg ccgtatcgat
    31561 gcctctatga aggctcttct acctcgtccg ccaaaacctg agcatgatga aaaaggtgaa
    31621 aagtctgagc gccctcaccg cccacgtcat caaaaggatt acaaacctaa gaaagaattt
    31681 acagaaacat caaaagattc agaataagaa aaggagaaat gtatggggtg gtggcgcgaa
    31741 accattgata ttgtaaaaga aaatgatcca gcggcccgca ccactttgga ggttttgctg
    31801 acttatccag gtgtcaaggc cttggcggcc caccgtctct cgcattttct ctggaagcac
    31861 ggcttcaaac tattagctcg tatgtacagt cagttttggc gcttttggac tcagattgag
    31921 attcatccag gagcccagat tgattcaggt gtttttattg accatggttc tggtctggtg
    31981 attggagaga cagcgattgt tgaaaaaggc gttcttctct atcacggagt gactctcggg
    32041 ggaacaggga aagactgtgg caaacgccat ccgactgtac gaaagggagc cctcatatca
    32101 gcccatgccc aagttatcgg gcctgtggaa attggtgaaa atgccaaggt cggtgctgca
    32161 gcagttgtcg tagcagatgt acctagtgac gtgacggttg tcggtattcc ggccaagatt
    32221 gtccgtcttc atggtaagaa agatgagcct gtcattcacg aagtcgaaga aaaacgagag
    32281 tattatgtca ataaactcga gcaggctaaa gatgccagtc acagatcgtc tggtttgtag
    32341 aggataccta tatgattcaa gcaagaaaca agttaagcca agaggagcta tctgaggcga
    32401 aaaaagtaat taactgttgc caaaactatg acggtaccta tcgcgatccc tatctctcta
    32461 acatgcttaa ttttgaccca aacatgcccg cctttttcct ttattatgaa aaaggcgaac
    32521 ttgttggttt attaactgtc tatgcagatg accaagatgt agaagtgacg atactggttc
    32581 atccaggtca tcgccgtcag gggattgcgc gtgcattgtt tactagtttt gagagagaaa
    32641 cagcttcttt ccccattcgg tcagtcactt ttcagacaga acgtattttt ttagagaatc
    32701 atcctgactt tgccagtaac tggggactaa tcgaggatga agagacagaa acttggttag
    32761 gtaaggatag aagaccttat ccgttagcaa atgtttccca tcttgaagtt ttgttagcag
    32821 atagttcgta tcaggatcaa attagtcaat taaaatttca ggcattttca gaggaacatg
    32881 aatcgagaga agttgtggat agatatgtcg ctgaagctct gaaagatcca gaaagccgac
    32941 tatatatttt attaaaagct ggtcaggtta ttggaacttg tacggttgat ttatcgacta
    33001 atacgaatta cctctacggt ttagcaatat tggaacctga acgtggaaaa ggctatggaa
    33061 gctacttagc aaaatccctc gtcaaccaac taattgagca aaatgacaag gaatttcaga
    33121 ttgcagtgga agatagcaat gtaggtgcca aacgtttgta tgaaaaaatt ggctttgtca
    33181 aacagactca ggtggtttat ctgaatgaga aaggagcaag ggattccgaa gtgtagagat
    33241 attcggactg aaatttactt gaacttttag tgatgaaact aattgttctt ggatttcagc
    33301 tttcctgatt atgatttatg attaaaatct atgacaccat gtctcgtgat ttgcgagaat
    33361 ttgtcccgat tgaggacggc aagatcaaga tgtatgtttg tgggccaacg gtgtacaact
    33421 atatccacgt aggaaacgcc cgttcgacgg tagcttttga taccattcgt cgctattttg
    33481 agtaccgtgg gtataaggtt gcctatattt ccaattttac agatgtggat gataagatta
    33541 tcaaccgtgc cagggaagaa ggtatcacgc ctcaggaggt tgcggataag tacatcgctg
    33601 cctttcgtga ggatgtgacg gcattgggcg tgaaacctgc gactcgccat ccgcgtgtag
    33661 tggagtttat ggcagacatc atccgttttg tggaagactt gatcgagaaa ggctttgcct
    33721 atgagagtca aggggatgtc tatttccgtg tagaaaaatc ccacaactat gctaaattgg
    33781 ctaataaaac cttggaagat ttggagctag gtgcttcagg tcgtaccgat gaagaaacgg
    33841 ctcgtaagga aaatcctgta gactttgctc tatggaaatc ttccaaacca ggtgagattt
    33901 cttgggatag tccttgggga cctggacgtc cgggttggca tattgagtgt tcagtcatgt
    33961 cgacagagat tttaggtgat accattgata tccacggtgg tggagctgac ctagagtttc
    34021 cacaccacac caatgaaatt gcccagtctg aagctaaaac aggcaaggct tttgctaact
    34081 actggatgca caatggcttt gtcaatatcg acaatgtcaa aatgtctaag tccttgggta
    34141 acttcattac ggtacacgat gcccttaaaa ctcttgatgg gcaagtactt cgtttcttct
    34201 ttgcgaccca gcactaccgt aagcctatca acttcacgga aaaggcagtt cgcgatgccg
    34261 agaccaatct caagtatctc aagaatactt acgaacaacc atttacagga aatgtggatg
    34321 cccaagagtt acaaaacttt aaagataagt ttgtagcagc tatggatgaa gattttaatg
    34381 ctgccaacgg tatcacagtt gtctttgaaa tggccaaatg gatcaactca gggaactatg
    34441 atgcaagtgt caagcaagct cttgcagata tgttagaaat ttttggaatt gtctttgttg
    34501 aggaagtttt ggatgcagag attgaagact tgattcaaaa acgccaagag gcgcgtgcca
    34561 atcgtgactt tgcgacagca gaccaaatcc gtgaccaatt ggttactcaa ggaattaagc
    34621 tccttgatac caaggatgga gtgaggtgga cacgtgattg atgtcaatct cattaacggg
    34681 attgcgctag cctttgaggg ggatgcggtg tattctatgt atattcgccg tcacctcatc
    34741 ctcaaaggta tgaccaaacc caataaactc catcaagaag caaccaagta tgtgtcagcc
    34801 aaggctcagg ctcgcctgat tgctctcatg ttggaggagc aggtcctaac ggaaaaagaa
    34861 gaagaaatct acaaacgtgg ccgcaatacc aatagccaca caaaggctaa aaatgcagat
    34921 gtcgtgactt atcgtatgtc cacgggattt gaagcggtta tgggctatct ccatatgact
    34981 gagaatctgg aacgtcttga gagtttggtt tcatggtgca tccaaaaagt ggagggctag
    35041 aacatgaggg aaaaagaact acaagactgg tttcctgatg ctcggatttc agaccaacca
    35101 gtagagaaag agggctatct cacgctccct ttagcttctc agcagtggat tttgctggag
    35161 gaagctgggc tcagcgagcg tgaaaagcag ttggttgccc ttttgaccca gcaggagcag
    35221 gctcgttcgc taaacccttg gtattcctat ctggttgagg gcaagggaca ggcaccgcaa
    35281 gtttttaaaa agattcagtt ggtttattgc catctttctt attttcagca ggaaaatctg
    35341 gcttcttggc tagatatgat gcggactctt tttccgaatt gtcagacagt gctacaggtc
    35401 ggagctcagg attatgtttt cgtgcttcaa caagacaaat acacttctgt aacagatatt
    35461 ttaagtgata tgattgaagc ggttgagtat gactttggac ttcgtctttc tatcatgttg
    35521 ggtcaggttt ggtctcagac aggacatcaa gccctatcag acttaatcaa agctgagcgg
    35581 gatttgttca agacatggtg gcgtcagggt caccaaggtg ttcatacttt ttctcagctc
    35641 tatctttgga gtatgggaga aagactcgtg gacttgaagc caattaaaga atgtctacac
    35701 cagatgattt tggatcaaga tcagattcag gaaatcattc tctctctttg ggaaaatagt
    35761 gctgttctca ctaaaacagc ccagcaactc tatctgcacc gcaattctct ccaatacaag
    35821 attgataaat gggaagagtt gacagggctt cagttgaaag agttgaccga cctgaccttg
    35881 tgttatcaat tgattttagg ttctttgtca actatagttg gtttgtaaag aagttaatat
    35941 ttggagaaga ggattgccat cttctccatt tttatgtgca gagttatagt ggcttgatgc
    36001 tgggaaagta cactgtgact gctaaaacat tcctagaagc tgctttgatt tccctaatct
    36061 atttatgcaa attttatgtt attttactat aacagttgtt gctaagccaa ataatagtgg
    36121 ggaagttcat ttagacgtaa gcattgaaga taatcaggga ggtagtgggc ataatttcag
    36181 ttctgtttca agtagctcac aaacagctaa atatgaagaa actggttata ataacaattc
    36241 atcattatat ataacgattg ataaaacgtc tgatgcaaca gctcttttga aattaaagtt
    36301 gaataatgtt gataatcaac ctgctactga agttcctagt tcaggaatta ctgtaaaatt
    36361 aaatgctaaa gataatgctg gaaactggac aagtgcttcg aataaaaaag aaataacagt
    36421 aaaaattgtt tctgctaaac cgacatatcc agacaaaatc ttagtgaaaa atcctgataa
    36481 tataaaagat acagaaaaaa atgccattat tgaaaaattg aaagaggcaa ataaaaatca
    36541 tccagcagga gctccaacct ttgctaaagg tgaaggagag catgcaaatg atattgtagc
    36601 aacttattca gatggtacaa cttattatgt accgttaaat gatgtgacaa aatatgcgag
    36661 gtagtggctg taccactcac ttattcacct ccccgtgatt tgtagtagtg ataggctttc
    36721 tcactattat tataaaacaa aataaagatc acaacacttt ttcattctgt gttgtgcctt
    36781 gagtgaaacg aaaggaatga attataaata tgaaaagtat agtcactagc atagatgagc
    36841 gcttgcgtac tcgcctacga gtgattatct ggaagcaatg gaagaagaaa tcgagacgat
    36901 tatggggatt gcttaagtta ggggttccta aatggatagc agataaggta tctggctggg
    36961 gcgaccacta tcaattgtag taaaatgaaa ta
//
LOCUS       DBEJNA010000021        36926 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEJNA010000021 DBEJNA010000000
VERSION     DBEJNA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.21"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            65..445
                     /locus_tag="ACL3JB_001169"
     CDS             65..445
                     /locus_tag="ACL3JB_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685900.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            980..1672
                     /locus_tag="ACL3JB_001170"
     CDS             980..1672
                     /locus_tag="ACL3JB_001170"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0685901.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1725..4136
                     /locus_tag="ACL3JB_001171"
     CDS             1725..4136
                     /locus_tag="ACL3JB_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0685902.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAALKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4386..5087
                     /locus_tag="ACL3JB_001172"
     CDS             4386..5087
                     /locus_tag="ACL3JB_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685903.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5089..7797
                     /locus_tag="ACL3JB_001173"
     CDS             5089..7797
                     /locus_tag="ACL3JB_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0685904.1"
                     /translation="MIKRKTYWKDLVQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7893..8384)
                     /gene="tpx"
                     /locus_tag="ACL3JB_001174"
     CDS             complement(7893..8384)
                     /gene="tpx"
                     /locus_tag="ACL3JB_001174"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0685905.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEDLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8507..9436)
                     /gene="psaA"
                     /locus_tag="ACL3JB_001175"
     CDS             complement(8507..9436)
                     /gene="psaA"
                     /locus_tag="ACL3JB_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0685906.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSEGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9468..10316)
                     /locus_tag="ACL3JB_001176"
     CDS             complement(9468..10316)
                     /locus_tag="ACL3JB_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0685907.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10313..11035)
                     /locus_tag="ACL3JB_001177"
     CDS             complement(10313..11035)
                     /locus_tag="ACL3JB_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0685908.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11335..13227
                     /gene="pepO"
                     /locus_tag="ACL3JB_001178"
     CDS             11335..13227
                     /gene="pepO"
                     /locus_tag="ACL3JB_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0685909.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPILSLLKEFQELETFADF
                     IAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13350..13979)
                     /locus_tag="ACL3JB_001179"
     CDS             complement(13350..13979)
                     /locus_tag="ACL3JB_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0685910.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14973..17195
                     /locus_tag="ACL3JB_001180"
     CDS             14973..17195
                     /locus_tag="ACL3JB_001180"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR0685911.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLSKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17225..17668
                     /gene="dtd"
                     /locus_tag="ACL3JB_001181"
     CDS             17225..17668
                     /gene="dtd"
                     /locus_tag="ACL3JB_001181"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0685912.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKLDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(18140..18553)
                     /locus_tag="ACL3JB_001182"
     CDS             complement(18140..18553)
                     /locus_tag="ACL3JB_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685913.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18684..19391)
                     /locus_tag="ACL3JB_001183"
     CDS             complement(18684..19391)
                     /locus_tag="ACL3JB_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGR0685914.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGP
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFSIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQMSQKQVKLTVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(19511..20161)
                     /locus_tag="ACL3JB_001184"
     CDS             complement(19511..20161)
                     /locus_tag="ACL3JB_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0685915.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20273..21115
                     /locus_tag="ACL3JB_001185"
     CDS             20273..21115
                     /locus_tag="ACL3JB_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0685916.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21191..21628
                     /locus_tag="ACL3JB_001186"
     CDS             21191..21628
                     /locus_tag="ACL3JB_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0685917.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21696..21998
                     /locus_tag="ACL3JB_001187"
     CDS             21696..21998
                     /locus_tag="ACL3JB_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685918.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(22089..23162)
                     /locus_tag="ACL3JB_001188"
     CDS             complement(22089..23162)
                     /locus_tag="ACL3JB_001188"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0685919.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23318..23995
                     /locus_tag="ACL3JB_001189"
     CDS             23318..23995
                     /locus_tag="ACL3JB_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0685920.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23988..24962
                     /locus_tag="ACL3JB_001190"
     CDS             23988..24962
                     /locus_tag="ACL3JB_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR0685921.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(25011..26954)
                     /gene="thrS"
                     /locus_tag="ACL3JB_001191"
     CDS             complement(25011..26954)
                     /gene="thrS"
                     /locus_tag="ACL3JB_001191"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0685922.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(27012..27188)
                     /locus_tag="ACL3JB_001192"
     CDS             complement(27012..27188)
                     /locus_tag="ACL3JB_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0685923.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(27195..27335)
                     /locus_tag="ACL3JB_001193"
     CDS             complement(27195..27335)
                     /locus_tag="ACL3JB_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0685924.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(27766..27966)
                     /locus_tag="ACL3JB_001194"
     CDS             complement(27766..27966)
                     /locus_tag="ACL3JB_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685925.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            28205..28834
                     /locus_tag="ACL3JB_001195"
     CDS             28205..28834
                     /locus_tag="ACL3JB_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0685926.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28975..29244
                     /gene="rpsO"
                     /locus_tag="ACL3JB_001196"
     CDS             28975..29244
                     /gene="rpsO"
                     /locus_tag="ACL3JB_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0685927.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            30060..30674
                     /locus_tag="ACL3JB_001197"
     CDS             30060..30674
                     /locus_tag="ACL3JB_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0685928.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30966..31715)
                     /locus_tag="ACL3JB_001198"
     CDS             complement(30966..31715)
                     /locus_tag="ACL3JB_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0685929.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31848..34184
                     /locus_tag="ACL3JB_001199"
     CDS             31848..34184
                     /locus_tag="ACL3JB_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0685930.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34286..34963
                     /locus_tag="ACL3JB_001200"
     CDS             34286..34963
                     /locus_tag="ACL3JB_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0685931.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            34950..35747
                     /locus_tag="ACL3JB_001201"
     CDS             34950..35747
                     /locus_tag="ACL3JB_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0685932.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            35764..36867
                     /locus_tag="ACL3JB_001202"
     CDS             35764..36867
                     /locus_tag="ACL3JB_001202"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0685933.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
BASE COUNT        10770 a         6930 c         8476 g        10750 t
ORIGIN      
        1 tacttttttt aaaagcaaat atgatacaat tttatttgaa aaaaataaaa aaggagattt
       61 tattatgaaa ttaaaaacac ttgctttaat tagtggtatc gtcggtcttg tgggaggaat
      121 tttacttctt attggtcctt ttgtcttgtt gggaacagcg gtaaacacag ctgctacaac
      181 tcttaatgga ggagctactg caggggcttt ttcaggtgtt gccttactct tgaatgcctt
      241 gaagattgca aatcttgttc ttggtatcat tgctattgtt tactataaag gagataagcg
      301 tgtaggtgca gctccgtctg tactaatgat tgtttctggt ggagttagtc tcattccatt
      361 cttaggatgg gttgggggga ttcttgctat tatcggagga tctctattcc ttgcaacatt
      421 gaagaaattc aaatcagaag aataaaaggt attttagcat gaaaagaaca aaaaagttta
      481 tcggtatagg agtagctcta ttatctcttt cttttctagt tgcatgtgga acataaagtt
      541 caaagaatac ttcaacaagt aatgatgaga agacagtagc aacatccaat agttcaaaag
      601 aaacaatcac tttcgataca ccggttgtaa cagacaatgc gattgaatca atacgcactt
      661 atgcagatta tatagatctt tataaaaata tttttgatga ttattttact aaagctgagg
      721 aaggtttcaa aggcacagct atggaaaata atgactcgtt tactaaacta aaagagtcaa
      781 ctcaaaaatt attcgatgcg cagaaaaaaa ggttaaataa tgaagataga atagaaacaa
      841 ccaaaaacaa tgtgattgcc aaacattgtc aaacagtcct ttcctttttg gttttgacta
      901 gcttttttgt gaaaaattgt gtaaaataga atagataaac gaggggaaac ctcggaaaat
      961 ttaaaggaga atccatctaa tggtaaaatt ggtttttgct cgccacggtg agtctgaatg
     1021 gaacaaagct aaccttttca ctggttgggc tgatgttgat ttgtctgaaa aaggtacaca
     1081 acaagcgatt gacgctggta aattgatcaa agaagctggt atcgaatttg accaagctta
     1141 cacttcagta ttgaaacgtg ctatcaaaac aactaacttg gctcttgaag cttctgacca
     1201 attgtgggtt ccagttgaaa aatcatggcg cttgaacgaa cgtcactacg gtggtttgac
     1261 tggtaaaaac aaagctgaag ctgctgaaca atttggtgat gagcaagttc acatctggcg
     1321 tcgttcatac gatgtattgc ctccaaacat ggaccgtgat gatgagcact cagctcacac
     1381 agaccgtcgt tacgcttcac ttgacgactc agttatccca gatgctgaaa acttgaaagt
     1441 gactttggaa cgtgctcttc cattctggga agataaaatc gctccagctc ttaaagatgg
     1501 taaaaacgta ttcgtaggag ctcacggtaa ctcaatccgt gcccttgtaa aacacatcaa
     1561 aggtttgtca gatgatgaga tcatggacgt ggaaatccct aacttcccac cattggtatt
     1621 cgaattcgac gaaaaattga acgttgtttc tgaatactac cttggaaaat aaaaaattgt
     1681 aagcctagga ttgatttcta ggctttttat gttagtatgg aagtatgata aggaataaaa
     1741 aacaagatta tgtactggcc tacaagcaac cagtttcaac cacttacatg ggttgggaag
     1801 aagaagcttt accgataggt aatggttctt taggagcaaa agtatttggc cttatagggg
     1861 ctgaacggat tcaatttaat gaaaaaagtc tctggtctgg aggtccactt cctgatagtt
     1921 cagattatca gggtggaaat cttcaggatc agtatgtttt tttagctgag attcggcagg
     1981 ctttggagaa gagagattac aatctggcta aggaactggc tgagcagcac ctaattgggc
     2041 caaaaacgag tcaatatggg acctatctgt cttttgggga tattcacatt gagttcagcc
     2101 agcaaggtac gactttgtct caggtgacgg actatcagag acagttgaat attagtaagg
     2161 cacttgcgac gacttcttat gtctataagg gaacgcgatt tgaacgtgaa gcttttgcga
     2221 gttttccaga tgatctcttg gttcaatgtt ttactaagga agggttggaa actctagatt
     2281 ttactataga actatccttg acctgtgatt tggcttctaa tggaaagtat gagcaggaaa
     2341 aatctgatta caaggagtgt aagttggata ttactgattc tcatatcttg atgaagggaa
     2401 gagttaagga taatgatctg cggtttgcta gttatctagc ttgggaaacg gatggagata
     2461 ttagagtttg gtcagatagg gttcagatat caggagccag ttatgccaat ctcttcttgg
     2521 ccgctaagac ggattttgcc caaaatcctg ctagcaatta tcgcaagaaa ctagatttag
     2581 agcaacaggt gatagacttg gtggacacag ctaaagaaaa gggctatacc caattgaaat
     2641 caaggcatat cgaggactac caagccttat tccagcgtgt tcaattggat ttggaagctg
     2701 atgttgacgc atccactaca gatgatttgt taaaaaatta taagccacaa gaagggcagg
     2761 ctttggagga gctgttcttc cagtatggac ggtatttatt gattagttcg tccagagact
     2821 gcccagatgc tctaccagct aacctacagg gagtctggaa tgcggtcgac aatcctcctt
     2881 ggaattcgga ctatcactta aatgtcaatc tgcagatgaa ttattggcca gcctatgtta
     2941 ccaatcttct agagacggtc tttccagtca tcaactatgt agatgatttg cgtgtctatg
     3001 gtcgtctagc ggctttaaag tatgcaggaa tcgtctctca gaaaggtgag gaaaatggtt
     3061 ggttggttca tactcaagcg actccctttg gttggacggc acctggttgg gattactatt
     3121 ggggttggtc accagctgcc aatgcgtgga tgatgcaaac cgtttatgaa gcctattcat
     3181 tttataggga ccaagactat cttagggaga aaatttatcc catgttgagg gaaacggttc
     3241 gtttttggaa tgccttttta cataaggatc agcaggcgca gcgttgggtg tcttctccgt
     3301 cttattcccc agaacatggg ccgatttcga ttggcaatac ctatgaccaa tctctgattt
     3361 ggcagttatt tcatgatttt attcaggctg ctcaggaatt gggactggat gaggacttgt
     3421 tgactgaggt taaggagaag tctgatttac taaatccttt gcaaatcact caatctggtc
     3481 gaatcaggga gtggtatgag gaggaagagc agtattttca aaatgagaaa gtggaggccc
     3541 agcatcggca cgcttcccat ctagtgggac tctatcctgg caatctcttt agctacaagg
     3601 gacaagagta tattgaagcg gcgcgtgcta gcctcaatga tcgtggagat ggcggcacag
     3661 gctggtccaa ggctaataag atcaatctct gggcgcgttt gggagatggc aatcgagccc
     3721 ataaattatt ggcagagcag ttaaagacat ccaccttgca aaatctttgg tgtagccatc
     3781 ctccttttca gatagatggt aattttggtg ctactagtgg catggcagaa atgttactcc
     3841 agtctcatgc agcttatctg gtacctctag ctgccctacc tgatgcttgg tcaacaggtt
     3901 ctgtttcagg cttaatggca cgtggacatt ttgaagtgag catgagctgg gaagataaaa
     3961 aactcttaca gttgaccatt ttatcaagga gtggaggaga tttgcgagtt tcttatccag
     4021 atattgagaa gagtgtgatt aaaatgaatc aagaaaaaat aaaagcgaaa tgcatgggga
     4081 aagattgtat ttcggtggca acagcagaag gtgatcttgt tcaattttat ttttaagaag
     4141 atgttataag gcagtaattt gaaactgcct tttaataagg atttaagaat ataagcagtt
     4201 ttcaactagt tgaaaaaacg ttataatgat aataggaagt aatactcaat gaaaatcaaa
     4261 gagcacaaac taggaagcta gccgcaggtt gctcaaaaca gtgttttgag gttgcagatg
     4321 gaagctgacg tggtttgaag agagattttc gaggagtata atttgtttga tagagggtgg
     4381 gtctgatggc ttatattgag atgaaacact gttacaagcg ttatcaggtt ggggacacgg
     4441 agattgtggc caattgtgat gtgaattttg agattgaaaa gggggagctg gttattatcc
     4501 ttggtgcttc aggtgcaggc aagtcaacag ttcttaacct tcttggggga atggatacca
     4561 atgatgaagg ggaaatctgg attgatggtg ttaatattgc ggattatagt tcccaccagc
     4621 gcaccaatta ccgtagaaat gatgtggggt ttgtttttca gttttataat ctagtttcta
     4681 atctgacagc taaggaaaat gtggaactgg cttctgaaat tgtgacagat gccttgaatc
     4741 ctgatcaagt cttgacagat gtaggtctgg ctcatcgtct caataacttt ccagcccagc
     4801 tttctggagg ggagcaacag cgagtctcca ttgcacgcgc ggtagccaaa aatcctaaaa
     4861 ttctcctttg tgatgaaccg actggagcct tggattatca gacgggcaag caggttttga
     4921 aaattctcca agacatgtct cgtcaaaagg gagcgacggt gatcatcgtg actcataatg
     4981 gagctttggc gcccattgct gatcgcgtga ttcaaatgca cgatgccagt gtcaaggatg
     5041 tggtgctcaa ccagcatcct caggatattg acagtttgga gtactagcat gatcaagcga
     5101 aaaacttatt ggaaggactt agttcagtcc ttcacaggct ccaaggggcg ttttttatcc
     5161 atcttgatcc tgatgatgtt gggatctcta gccttagtag gcctcaaagt aaccagtccc
     5221 aacatggagg cgacagctaa tgcttattta acaactgctc aaaccttgga tttggcagtc
     5281 atgtctaact atggcttgga tcaagcagac caagaagaac taaaacagac ggagggcgca
     5341 gaggtcgagt ttggctattt gacagatgtg actatggata atgggcagga tgccattcgg
     5401 ctgtactcca aaccagagcg aatttcaacc tttcagctaa gaaagggacg acttcctcag
     5461 tcagacaagg aaatcgcttt ggccactcat ttgcaaggcc aatacagcgt gggacaggag
     5521 attagtttta aagaaaaaga agagggtcat tcctctttaa aagaccatac ttataccatt
     5581 actggttttg tggattcggc tgaaatcctc tcccagcgag atatgggcta cgcaggaagt
     5641 ggaagtggga ctctgacagc ctatggggtg attttaccta gtcagtttga tcagaaagtc
     5701 tacaatatag ctcgtttgaa atatcaagat ttagcaggtt taaatgcctt ttcatcagct
     5761 tatgaagaaa aatccaagca acatcaggaa gaccttgaac aaactttatc agataatggc
     5821 aaggtacgtc tgcaactttt gaaaaaagaa ggacaagagt ctctagacaa ggggcaagag
     5881 acccttgaca aggctcagac taatttgcag gaaggcaagc gtcgtttagc agctgctcaa
     5941 gctcgtatac aggctcaaga aagtcaacta gccttgtttc ctcaagttca gagagagcag
     6001 gctagtgctc aacttaccca agccaagcag gaattgggca aggaagagga taaactaaag
     6061 caagctgaac aaaatctagc ccaagaaaag gaaaaattag aaaaacatca gcaagtcttg
     6121 gacgatttgg cggagccaag gtatcaggtc tataatcgtc agaccatgcc aggtggtcag
     6181 ggctatctta tgtatagcaa tgcttcatcc agtattcgag cagtgggcaa tatctttcct
     6241 gtggtacttt atgccgtagc atccatggtg acctttacga ccatgactcg ctttgtagac
     6301 gaagagcgaa ctcatgcagg gatttttaag gccttgggtt accgtagtaa ggatattatc
     6361 accaagtttc tcctttatgg actagtagct gggactgtcg gaacggctct aggtagtata
     6421 cttggtcatt atttgctagc cagtgtaatt tcaagtgtca ttacaaaagg catggtggtg
     6481 ggagaaaccc agattcagtt ctattggacc tatagcttac tagctcttgt cttgagcttg
     6541 ttggcgagtg tgttaccagc ctatctggtg gcttggaggg aacttcatgc cgaagcagcc
     6601 cagcttctac ttcctaaacc tcctgtcaaa ggagctaaaa tcttattgga gcgtatcggt
     6661 tttatctggc gtcgtctcag ttttactcat aaggtaacag cccgcaacat ctttcgttat
     6721 aagcagagaa tgttgatgac aatctttggt gtggcaggtt ctgtagctct gctctttgca
     6781 ggtttgggaa tccaatcttc tgtagcagga gttccgtcta aacagtttca acaaatccaa
     6841 cagtatcaga tgcttgtctc tgaaaatcct agtgcgacca atcaggacaa ggtagagcta
     6901 gcagaagtat tgaaagggca ggagatacta gcctaccaga aaatctattc taaaacgcta
     6961 gacaaggatt tcaaaggcaa ggctggtctt caaaacatta ctcttatgat gatagagaag
     7021 gaagatttga ctccctttat ccatcttcaa catcatcagc aggagctgac attaaaagat
     7081 ggcatcgtta ttacagctaa actcgcccag ctggcaggtg tcaaggttgg gcagacttta
     7141 gaaattgaag gtaaggaact aaaggtcgct gctattactg agaactacgt tggtcacttt
     7201 atttatatga gtcaggctag ctatgagcaa ctttacggac agctacccca agccaacact
     7261 tatctggtct cattaaggga taccagtgca actagtatcg aaagtcaggc gggcttgctt
     7321 atgaatcaat ctgcggtgtc cagcgttgtc caaaatgctt cagccattcg actcttcgac
     7381 tctatcgcta gctcactcaa tcagaccatg accatcttgg tcatcgtatc ggttctatta
     7441 gctattgtca tcctttacaa tctgaccaat atcaacgtag ctgagagaat ccgtgaactc
     7501 tccactacca aggttctcgg ttttcataat aatgaagtca cactctacat ttaccgtgag
     7561 acgattgtgc tatcccttgt gggaatcgta cttggtctgg tagctggttt ctatttacac
     7621 caatttttga ttcaaatgat ttcgcctgcg actattctct tttatccgca ggtaggctgg
     7681 gaagtctatg taatcccagt ggcagcagta agcatcattt tgaccttgct tggtttcttc
     7741 gtcaattatt atctgagaaa ggttgatatg ttagaagccc tgaaatctgt agagtaaggt
     7801 agttattttt agctgattga acttctattt actaatattc aaaaatcctc cgtttcaaag
     7861 agcagggaac tctttgtgac agaggatttt ttctataggg ctttagcagc tgcaattgcg
     7921 gcttcgaagt ttggctcaga attgatatta tccacgtatt caacgtagcg aatcgtattg
     7981 tcagtatcga ggacaaagac tgcgcgtgct aataggtgcc attcgttgat caagagggca
     8041 taatcgcgcc cgaaagaatg gtcaaagtag tctgaaagca taatggcatt gtcaaggtct
     8101 tcagcaccgc accaacgttt ttgagcaaaa ggtaggtcca ttgaaacagt caatacgacc
     8161 gtgttgtcca gtccagccaa ttcttcatta aaacgacgtg tttgagttga gcagatgcct
     8221 gtatcgatag aaggaacgac actcaagact tttttcttgc catcaaaatc agccagagat
     8281 tttttagaaa gatctgttgt agtaagagaa aaatcaagcg ccttgtcgcc gacttgtagt
     8341 tgtttacctg taaagctcac aggatttccg agaaaagtta ccataggata ctccaatctt
     8401 ttttcttcca ttgtatctga aacagtcaga attttccaat gatttgaccg gaaatgtggg
     8461 catagaaaaa acgccagctc acatgagaat gacgtttttc agaggcttat tttgccaatc
     8521 cttcagcaat cttgtcaagg ttgtatttca tcatgctgta gtagctgtcg ccttctttac
     8581 cttgttctgc gatagagtca gtaaagattt gtgcgtagat tgggatgttt gtgtcttgag
     8641 aaacagtttt cattggacgg tcatccacac ttgattctac aaagagtgat ggaacttttg
     8701 tttggcgaag tttttcaacc aaggtcttga tttgttcagg agttccttct tcttcagtat
     8761 tgatttccca gatgtaggca cttggaacac cataggcttt agagaagtat ttgaatgctc
     8821 cttcgctggt tacaatgagt ttcttttcag cagggatctt attaaattta tccttacttt
     8881 ctttatcaag tttgtctaac ttatcagtat attctttgag atttttttca tagaattctt
     8941 tattgttagg gtctttggcg ctcaattgtt tggcgatatt tttagcaaaa ataataccgt
     9001 tttcaaggtt aagccaagcg tgtgggtctt cttttccttt ttcattttga ccttcaaggt
     9061 agataacatc aacgccttcg ctgactgcga agtagtcttt gttttcagtt ttcttggcat
     9121 tttctaccaa ttttgtaaac caagcattgc cacctgtttc aaggttgata ccgttataga
     9181 aaatcaaatc agcctcagaa gttttcttaa cgtcttcagg aagtggttcg tattcgtgtg
     9241 ggtcttgccc aatcggaacg atactatgaa ggtcaatttt gtcaccagca atatttttag
     9301 taatatcagc gatgattgag tttgtagcaa caacttttag tttttgacca gaagttgtat
     9361 ctttttttcc gctagcacat gctacaagaa tgattgcaga aagaaagaga acgagtaatg
     9421 tacctaattt tttcattaga tcctccaatt tattagggct ttgcccctta ttttaacaaa
     9481 tgtttatttt tcagtttcaa atatcgttgt ttgggagcga taaagaagct aatgagaaag
     9541 aaactagcag ctgtaagcac gatactagaa cctgccgcaa cattaaaact atagccaata
     9601 aagagtccca aaactgaagc agtagctccg aaggttgagg aaaggaaaat catacttttc
     9661 agactattag catacagata agcagttgca gctggggtaa tcagcatggc tacaatcagg
     9721 atagttccga cactttgcat ggctgtcaca gacacgagag tcaggagtac catgagaagg
     9781 tagtgataga aattgacagg cattcccatg gctttagcca agagttcatc aaaggaagtt
     9841 atcaagagtt gcttgaagaa aatccagatt aacaagagga tggctgcccc cacacccata
     9901 gtaataaaca tatccgtatc ttggacggcc aggatattac caaaaaggat atggaaaagg
     9961 tcagttgaac ttttagcgac accaatcaag atgataccga gggctaagaa agaagaaaag
    10021 gtaatgccga tggcggtatc gcttttgata atcgagtttc ctttgatgta ggtaatgatg
    10081 atggcagcta gcaatccaaa gacaatggct ccgataaaga agtcaaggcc caagatgaag
    10141 gagagggcta cacctggtaa gacagcatgt gaaatggcat ctcccatgag tgacatcccg
    10201 cgtagaataa tgaaacatcc cacagctcca gctacaatcc cgacgacaat agctgttatc
    10261 aaggcatttt gtaggaaatg gaatttttgc aatccatcga taaattctgc aatcataggt
    10321 cacctccatt gaaaaagagt tgattaccgt aagcttcttt tagattggtt tcggtaaaag
    10381 tttcttttgt tggaccaaag gcaatcactt ctcgattgac aagtaagact tgatcgaagt
    10441 agtggggaat cttgctgagg tcgtggtgaa cgatgagaac cgtcttccca gcttttttca
    10501 aatctctcag cgtattcatg atgatttcct cactgacaga gtcaatccca gcaaagggtt
    10561 catccaagag gatatagtcg gcttcctgca ccaaacatct ggcaatcaag acccgctgga
    10621 attgacctcc agacagttga ctaatttgac gttcagcgta gtcagctagg ccgacgattt
    10681 caagggcctc ttgcactttc ttccaatgtt tagcctttaa acttcgaaag agaggaatag
    10741 agggaaatag tcctaacgag acgcattcct tgaccttgat gggaaagttg tagtcgatat
    10801 tgattttttg ttcgacatag gcaattcggt gtaaggattt tttaacttcc ttgtcatcga
    10861 gaaatgcctg accttgatgt gggataattc ccagcatacc ttttaatagt gttgatttcc
    10921 cagcgccgtt tggaccaatg atgccggtaa ttgttggtcc atggagcact agtgaaatat
    10981 ccttaagtgc caacgtttct ttgtaggaga cactgaggtt ttcgatacgt atcataaact
    11041 tgtattcctc ctgtctctta atatacatta aaaaaaaaat taagtcaagt taatttttga
    11101 aaaaattaaa ataataactg aaaaatagat tctaaagata actttcagga taaatttcta
    11161 aattataaaa cgcatagtat gcatagtatc aagtgtaaaa aacttggaat tatgcgtttt
    11221 atcatggaaa gattctttat aatagctaaa aaataatagt taaatggtta ctaattgcat
    11281 tccctagtga tttttgttaa gataaaggca aatacaaatg aaagcgagaa caagatgaca
    11341 cgttatcaag atgattttta tgatgctatc aatggagaat ggcaacagac agctgaaatc
    11401 ccagcagata agtctcaaac aggaggtttt gttgatttag accaggaaat tgaagacttg
    11461 atgctggcga caacagacaa gtggttagca ggtgaagaag tgcctgagga tgctatcttg
    11521 gaaaactttg tcaaatacca ccgcctagtt cgtgattttg acaagagaga agctgacggt
    11581 atcacaccta tcttatcact ccttaaagaa tttcaagaat tggagacttt tgcggatttt
    11641 atagctaaac tagcagagtt tgagcttgca ggaaaaccaa acttccttcc ttttggtgta
    11701 tcgccagact ttatggatgc tagaatcaat gttctatggg ctagcgctcc aagcacaatc
    11761 ttgccagata cgacctacta tgcagaagaa catcctcagc gcgaagagct cttgactctt
    11821 tggaaagaaa gcagcgcaaa tctcctcaag gcttatgatt tctctgatga agaaattgaa
    11881 gacttgctag aaaaaagact tgaattggac cgccgagttg cggcagtggt gctctctaat
    11941 gaagaaagtt cagaatatgc taaactctat catccatatt cttacgaaga tttcaagaaa
    12001 ttcgcgcctg ccctaccttt ggatgacttc ttcaaagcag ttattgggca attaccagac
    12061 aaggttattg tagacgagga acgtttctgg caagcagcag agcaattcta cagtgaggaa
    12121 gcctggtctc tccttaaagc aaccttgatt ttgagtgttg tcaatctttc aaccagctat
    12181 ttaacagagg atatccgtgt tttgtctggt gcctacagcc gtgccctttc tggagttcca
    12241 gaggcaaaag ataaggtcaa agcagcttat catctagcac aagaaccttt caagcaagcc
    12301 ctgggtcttt ggtacgcccg tgagaagttc tctccagaag ccaaggcgga tgtggagaaa
    12361 aaagtggcaa ccatgattga tgtctataag gagcgtctgc ttaagaatga ctggctcact
    12421 ccagaaacct gtaaacaggc tatcgtgaag ctcaatgtga tcaaacctta tattggctat
    12481 ccagaagaat tgcctgcacg ttacaaggat aaggtagtga atgaaactgc cagtcttttt
    12541 gagaatgctc tagcctttgc gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag
    12601 cctgtagatt ataaggaatg gggcatgcct gctcatatgg tcaatgccta ctacaatcct
    12661 cagaagaacc tgattgtctt tccagcggcc attttacagg cgcctttcta tgacttgcat
    12721 cagtcatctt ctgctaacta cggtggtatt ggggcagtga ttgcccatga aatttcccac
    12781 gcctttgata ctaacggggc ttcctttgac gaaaatggta gcctcaagga ttggtggaca
    12841 gagagcgact atgctgcctt caaggagaaa acacaaaaag tcattgacca atttgatgga
    12901 caggattctt atggagcaac cattaacggt aaattgactg tatcagaaaa cgtggctgac
    12961 ttgggaggaa tcgcagcagc gcttgaagca gctaagagag aagcagactt ctcagcagaa
    13021 gagttcttct acaacttcgg tcgcatctgg cgcatgaaag gtcgaccaga atttatgaaa
    13081 cttttggcta gcgtcgatgt gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca
    13141 aacttcgacg atttctttac aacctatgat gtcaaagaag gagacggaat gtggcgttca
    13201 ccagaggagc gcgtgattat ttggtaatac aaaaaatcta gtcatcagaa aaaaggcatc
    13261 caatcacgtg tgaaaacctt gataggatgc cttttgtaat agaaagattt gctggatagt
    13321 ttacttaaat ttcgattgtc atcatcttgc tagaaaaagg gattgaaggc cttttcgtga
    13381 gcgatagtag tagctggacc atgtcctgga tagacatcgt agtttggtag ggtgaagagt
    13441 tgggtctgga tactatgaag gagttgctcc atgctaccag tcggaaggtc ggtccgtccg
    13501 atagtttcgc ggaatagagc atctcccgtc aagactaggt gagcatcagg aaagactagg
    13561 gaaacaccac cgatagagtg ccctggggtc ggtagaacct taaaacgaaa ttcctctagt
    13621 tggtattctt cgtgaaagac aaaggtgtgt tctgcaggtt ttgtgaccac atctgccata
    13681 tcatcgtggc gagggagacc ggagagatta tcgacaggag tgtagagcca gctggcttcg
    13741 ctctctgcga tatagacagg aggattgcca aacgtctcgc gaaccaagtc cagactcatg
    13801 atatggtcat aatgggcgtg ggtcaagaga atagcacaga tcggtttgtt gatcttctcg
    13861 attgtctgac gaatggcttc ccaatgacta ccaggatcga cgacgatgag gtgcttttcg
    13921 ccttctagat aataggtatt ttcataggca acaggattca cggttttatg gattttcata
    13981 ctagctccaa tctcaaagaa tgtactaata ctcttcgaaa atctcttcaa accgcgtcaa
    14041 ctttatctgc aacctcaaag cagtgctttg aacagcctgc ggctagcttt ctagtttgct
    14101 ctttgatttt cattgagtat aaattaagta tagcacagtt agggagaata ggtaaggatt
    14161 taaaatgaac ttaaaaacca gcatgactag atgaagacag gctggttatc aatttatcaa
    14221 tattggaaag gtgtcaattg cccttcatag gttgcataaa ctccgtcatt agcttgtttg
    14281 atagacgtga tgtttagagt gctaccgtag ttggcttctc atttgtcgct atattcacta
    14341 taagttatcc tactgggcag gttctggtcg ttagcatagt attgaacgag ttttttatag
    14401 ctttgctggc tgaataggaa caggcagcaa actcctaaca ttaggagagc aaagatagaa
    14461 atagcagttt ttttcatagg tattctcctt ataaactaaa ggatagaaga aagtatcttg
    14521 aggattttta tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct tgccgtatat
    14581 atgtgactga ctttgtcagt cttatctaca acctcaaagc agtgctttga gcaacctgcg
    14641 gctagtttcc tagtttgctc tttgattttc attgagtatt aattccaaaa tccagtcaag
    14701 gtaccagtgt atgtgatacg agttccaccg tttatctttc gtatcttcaa tggaattggg
    14761 gaaatcagaa agtctttggg ttacaatatg gtttccgttc ttctatctct ccttctatca
    14821 cctaagttta aaatctaact tcgtagtata ttatgggcca ataattcaga attatcaagc
    14881 aattttgaat tatttttttc ttattctgtt ccaatctagt tttcatattc ttaaaaaagt
    14941 gataaaatgg taggaagaat tggagagtag agatgccgaa agaagtgaat ttaacaggcg
    15001 aagaagttgt cgctttaacc aaagaatatt taacggaaga ggatgttcat tttgtccata
    15061 aggccttggt ctatgctgtt gaatgccaca gtggtcaata tcgcaaatca ggcgagcctt
    15121 atatcattca ccctatccaa gtggcaggta ttttagctaa gctaaagctg gatgctgtaa
    15181 cagtagcttg tggattcttg catgatgtgg tggaagatac agatgcgacc ttggacgatt
    15241 tggaaagaga gtttggtcct gatgtgcggg tgattgttga cggagttacc aagcttagca
    15301 aggtcgagta caaatcgatc gaggagcaat tagcggaaaa tcatcgcaag atgctcatgg
    15361 ccatgtctga ggacatccgc gttattttgg tcaaactgtc tgaccgcttg cacaatatgc
    15421 ggaccctgaa acatcttcga aaagacaagc aggagcgtat ttccaaagaa accatggaaa
    15481 tctatgcccc acttgcccat cgtttgggga tttccagtgt caaatgggaa ttagaagact
    15541 tgtctttccg ttatctcaat ccaacggagt tttacaagat tacccatatg atgaaggaaa
    15601 agcgcaggga gcgtgaggcc ttggtggatg aggtagtcac aaaattagag gagtacacga
    15661 cagaacgtca cttgaaaggg aagatttatg gtcgtcccaa gcatatttac tcaattttcc
    15721 gcaaaatgca ggacaagaga aaacggtttg aggaaatcta tgatctgatt gctattcgtt
    15781 gtattttaga tacccaaagt gatgtttatg ccatgcttgg ttacgtgcat gaattttgga
    15841 aaccgatgcc aggtcgcttc aaagactata ttgccaaccg caaggccaat ggttatcagt
    15901 ctatccatac gactgtttat ggaccaaaag ggccgattga attccagatt cgaaccaagg
    15961 aaatgcacga ggtggctgag tacggggttg cggctcactg ggcttataag aaaggtataa
    16021 aggggcaagt taacagcaag gaatcagcta ttggaatgaa ctggatcaag gagatgatgg
    16081 agctccaaga ccaggctgat gatgctaagg aatttgtgga ctctgttaag gaaaactatt
    16141 tggctgagga gatttacgtt tttaccccag atggagctgt ccgttccctt cccaaagatt
    16201 caggaccgat tgattttgcc tacgaaatcc ataccaaggt cggtgaaaaa gcaactggtg
    16261 ccaaggtcaa tggccgcatg gttccactga caaccaagtt aaagacaggg gatcaggttg
    16321 aaattatcgc caacccgaac tcctttggac ctagccgtga ctggctcaat atggtcaaga
    16381 ctagcaaggc gcgcaataag attcgccagt tctttaaaaa ccaagataag gaattgtctg
    16441 tcaacaaggg tcgtgagatg ctgatggctc agttccaaga aaatggctat gtggcaaata
    16501 aatttatgga caagcgccac atggatcaag ttctgcaaaa gaccagttac aagacagaag
    16561 actccctctt tgcggccatt ggttttgggg aaatcggtgc gattaccgtc tttaaccgtc
    16621 tgactgaaaa ggaacgccgt gaggaagagc gtgccaaggc caaggctgag gcagaggagc
    16681 ttgtcaaagg tggcgaggtc aaggttgaaa ataaagaaac tctcaaggtc aagcatgagg
    16741 ggggagtggt tattgaaggt gcttctggtc tcctagtgcg gattgctaag tgttgtaacc
    16801 ccgtgcctgg tgacgatatt gttggctaca ttaccaaggg tcgtggtgtg gctattcacc
    16861 gtgtggactg tatgaacctg cgtgcccaag aaaactacga gcaacgtctc cttgatgtgg
    16921 aatgggaaga ccagtactct agctcaaata aggagtatat ggcccatatc gatatctacg
    16981 gtctcaaccg tacaggactg ttgaacgatg tactgcaagt tctttcaaat acaaccaaga
    17041 atatttcaac ggtcaatgcc caaccaacca aggatatgaa gtttgctaat atccatgtgt
    17101 ccttcggtat tgccaacctc tctacactga ccacggttgt cgataaaatt aagagtgtgc
    17161 cagaagttta ctctgtcaaa cggaccaacg gctagttgtc ctagctctta ctagaaaggc
    17221 tattatgaaa atcattatcc aacgggttaa aaaagcccaa gtgagtatag aaggccagat
    17281 tcagggaaaa atcaatcagg gacttttatt gctggttggt gttggaccag aggaccaaga
    17341 ggaagatttg gactatgctg tgagaaaact ggtcaatatg cggatttttt cagacgcaga
    17401 aggcaagatg aacctgtctg tcaaagatat tgaaggagaa atcctctcta tttctcagtt
    17461 taccctcttt gcggatacta agaaaggcaa tcgtccagcc tttacagggg cagctaaact
    17521 tgatatggca tcagacttct atgatgcttt caatcaaaaa ttagcgcaag aagtgcccgt
    17581 tcagacaggc atctttggag cagatatgca ggttgagctg gttaataacg gacctgttac
    17641 cattatccta gatactaaaa agagataaga aagaccaagc ccagtcggct tggtctttct
    17701 catctatcat aaaatactcc aaaaagaaat cggttcttga tatgcttggg ggaagtctct
    17761 tttcaggctt tggcagatgc gataggaagg gatgagatgt cctaggatga ggagagttcc
    17821 ctgaaggaaa agtggaatat cacttaaaga caccaaggag agaatcatca ggctatccca
    17881 taggagaatt tgtaaagcaa aacgccagaa tctcggtcta atctgggaat agagttaact
    17941 aaagtggtca caaagttggt ttgaaagata ggtcaatagc acaggatgaa agaaaatgag
    18001 ccaaccgcta taaatcaaaa tccagtccca agtaagcccc ccttttaaat gtcaaaaatg
    18061 ctagcatgat tccatcaatg acaaggagtt gaatggtttt gatgaagatg atttttttca
    18121 tgctaaaacc tccttttcct tagagacact cccataaaga gatgtgtttg tcgtaaaagt
    18181 ctggatagtt ttctcttagg tagtcagctg tcatataata aaaagtagaa tggcaagcag
    18241 tgatgattgg cataagagat gaaaaacgct gagaactaat gaaggctaag agaacaaaaa
    18301 atagaaaatc aatggtgaga acccctaaat agtagaagcg aatcttttta ttgatttgag
    18361 gataaatctc agcgaattga tgtttgagtc ggacgatcaa gagaaatagc aggagtcctt
    18421 gagcaaggaa gaaaattaaa ccagagagca agagccactc aaaagatgtc tcgagtctaa
    18481 tgataaaaaa tgcaaatagt agcaaatcaa taactgcaat tgctataaaa tggattctat
    18541 agagtttttt catgacaaga cctccctctt ttatctaact tcattctact ccaaaagaat
    18601 gggagttaca actaaaatga taaaaatagc agaagggaga ttctcttaag ttggctagta
    18661 ttctttattt gagtttcctt ctattatcta acttcttcat cattccagac aaataaagct
    18721 ccgattgcat tgaggatata aaagatgtat ttaccgatat tggcgaagtt tccttgaata
    18781 ccagcttttg tcagctgaac gaaattgtaa atcaaccaaa agccccactg agttgttagt
    18841 tttaatgcat tcaaagcatt ggcaatgagg gatagtgcaa aggcaatagt tgttacgtag
    18901 gcaaggagat tcatcttgcc ctcatatccg atatagttgg tcacaaaggc aaagaggaag
    18961 gcgatgatgg aaatgatgat gaccgtcaat tttacctgtt tttggctcat ttggttgggt
    19021 ctgccttctt gcgaagcttt ccatttcttt atagcaaagg tataaatgag gaaggtgacg
    19081 ggataggtaa tgatggccgc cttatttcca aggatataat caatagcacc ggacaaaatg
    19141 gtattaacaa tactaaagta atttccccat ttgcttaatt tccccgtgaa acgagtggac
    19201 aacatggaaa tcccaacgtt ggttacggaa atcaatccaa agggtacaag agctgtccat
    19261 ggtccccagt ctacaaattt atcgaggcgt gagttgaggt aaccagatgc aatcgcaatc
    19321 ccaacgacca aagcaacccc gaagaggtca aaccatttag atgtagcaaa aatttttagt
    19381 gattttttca taggttaaac tacctttctt ttttttttca aatattctac caccaaatga
    19441 aagtaaaata aaatgataga aataaaaccc tgaaaataaa actttcaggg ttggtagggg
    19501 acttgagaaa ttagttgatt ttctcgacat agagttgttt tgcaatgtcc atattcactt
    19561 gtaaatcctc gtcgttactg aggatagtga aggtattgct gaagccatca aactgcttga
    19621 cttggagctg gtcaccgatg tgaagtgagt gcttgtccag ataatggaga atgtcaaaat
    19681 tatcgtgcac ccgagtcagg cggtaggcgc cagcttcctt gatatcagct agtgggaggt
    19741 tattgatttc aacgaggagt tctcccttgg caggaatagt tcctccgtgg gggcaggttt
    19801 tagggaaacc tagcagttta tctagtcttt ccacgaacag gtcagagaca gtgtgttcca
    19861 agacctcagc ttcctcgtga atctggtcac ttgtatagtc taaatgatga actagaaaaa
    19921 cttcaatcaa gcggtgctta cgatagagct cagagaccag tttgagaccg aggtcagtca
    19981 gtagatagcc acattccttg tcctttagga tgagattttc acttttcatt cgtttgatca
    20041 tttcagttac ggcaggggga gagacttgca tgcgagccgc aatttccttg ttggtaatct
    20101 tatgcaggtc tatgccaatt tcataaatac attttagata gtcttctttg tttggggtca
    20161 ttcgtttcct cttgtctaat atctttatct agtatatcaa aaaaagctag atttctctag
    20221 ctgtgacttt ttatgttata cttattgcaa gagaaaaaac gaggagatgg atatgacgaa
    20281 aatagctctt ctttcagata ttcatggaaa taccaccgcc ttggaggctg ttttggcaga
    20341 tgctcagcag ctaggagtgg atgaatactg gcttttggga gatattctca tgccagggac
    20401 aggacgtaga aggattttgg acttgttgga tcaactaccg attacggcta gagttttggg
    20461 aaactgggaa gacagtcttt ggcatggtgt ccgtaaggaa ttggacagta ctcgccccag
    20521 tcaacgctat ctcttgcgcc agtgccagta tgttttagag gaaatttccc tagaagaaat
    20581 tgaagtgctc cacaatcaac ctcttcaaat tcatcgtcag tttggggatt tgacggtggg
    20641 aattagccat catctgcctg ataagaactg ggggcgagag ttgattcata ctggcaaaca
    20701 agaggagttt gaccgcttgg tgactcatcc tccctgtgat attgctgttt atggacatat
    20761 tcaccagcag ttgcttcgtt acgggactgg tgggcaattg attgtcaatc cgggttcgat
    20821 tggccaacct ttctttttgg acgctcagct acggaaggac ttgcgggccc agtatatgat
    20881 tttggagttt gatgacaagg gcctggtaga tatggacttc cgacgggtag attacgatgt
    20941 ggcagctgaa ttgcagctgg ctaaagacct gagacttccc tattttgagg tttactatga
    21001 aagtctggtc aatgggatcc accatactca tcatcaggaa tttttgagag aattggctca
    21061 gaaagagggc tgcgatcggg agttagacga ctggttgaaa agtggtaacg attgacatta
    21121 caactaaaaa gggtataata atagaaaaag aagagtagag gcagggtagc ctcgtaaaaa
    21181 ggagaagagg atgcaaattc caagtagatt taccattgcg actcatatgc tgataatcat
    21241 tgccctcgag gggaaggaaa gcaaggtgac cagtgatttt ctggctgcta gtgtcggggt
    21301 caatcctgtc attatcagaa agatcttgtc ccagttgaag aaggcagagc tgatttcagt
    21361 agcgcgtgga acgggcggaa cagagattgt caaggacctt aaggatatta gtcttttaga
    21421 tgtttatcag gcggtcgaat gtcttggtaa gacaggtcaa ctcttcagtt tccatgacaa
    21481 tccgaatcca aattgccctg taggagctca tattcatgat gttttggatc aaaaattgga
    21541 gagaattcag ttgactatgg aggcagaact tggtcaaacc agtctagaaa aagtcgtggc
    21601 cgatgcagag agtcagatga aggattaaga gggataaatg ccctcttttt tctttggata
    21661 attatgataa aatgtagcta ttaaaggagt aagaaatgta tctcgttata ggaattgtat
    21721 tagcctttat agtgtcattt tggaaggata atagaagttt gtggaatcca gtattatttt
    21781 tattatccct catttcaagt tatttttatc tatcctacct tttttataaa aatggatacg
    21841 agaatgttca gttagctttt tatgtatttg cctttgtctt acttcctttt ttgctttttc
    21901 taagtggcat ctttttaatc tataatgggg tcattttgtt gaagcgagag ggacgttcca
    21961 agccccatta tctctcaatg ctctttgatt tttattgact attagattct atttaaaaag
    22021 acttagaatg cacatgaaag tatgtattct aggtcttttg ttttgtatac atttaattgt
    22081 caagagtatt atctattttt ccatgcctgg taacgagtat caatcaataa ctgggtaagg
    22141 cgacccaagg tttctctttc ttctggagtg agggattgag cttggacaaa gagatgatga
    22201 atgtattcaa gcgcctttaa ggaagccaag tcattgatag agctaatacc agcctcaaga
    22261 atagtgccaa agaagaggtc gaagtagagc tgaagttctt cgtcagggac tgtggccacc
    22321 cattctttaa aggttgtgtc tacttgctgg ctatcactgt tggtcttatc cagttggacg
    22381 aagtgcttgt cctcaatctg ccaactaaag gtatcgtgct gggcgatgcc acccagggca
    22441 gtactctgaa cgatgatttg gtgagcagga atttccagca tcataccgat aatggaacct
    22501 tgtggaatga atatcttgct tctatccatt atcctttgat aacccgcagt ctgtgtcaat
    22561 tcttgatgga gaccaggtgc atcaaatgta taaactgctg tgatctgatt ttgcaaactt
    22621 tgctcaattt ggctagcagc atagatagcg agatttcctc ccttggaatg cccagctaga
    22681 ataacctttt gcttaggatg atgggcaaaa aagttcttta aatagcgaag ggcgtgcttt
    22741 tgagcaggaa tttccttcat ataggtcagg tggaaatctt ccttccagcc aatgatactg
    22801 tcatctgtcc cacgaaagac aatcagatag gtatcgaggc tgacacgata agtcatagcc
    22861 gcaaattgct tttgcagttc agggtcgatg tcgttgataa aatgggagag tttgcaattt
    22921 ttgaagcgct tgtgttgagc caattcatct aataattgaa ggcgattttt gctagtaagc
    22981 atggtgggat ctcttggaac ctgaggtgct agatctaaaa gacgttgagg aagtgtggag
    23041 accagattat caaaggagag gtaggtgatt tctattaagg ttagaatgtc taactcattc
    23101 aagggaaggt cgtaataaga atcatatgcg acatctttca gatagtcaaa aatattggcc
    23161 ataagagctc ctttcttttt atttatctta gcaaatttcc ctcaaattag ctagtagcat
    23221 tgcctgtttg tactggctaa aaacaggcta tttcaaattc agtttcagac catctggcat
    23281 ggaaaaatct gttataataa tagaaaagga gaagcgcatg cacaagattt tattaataga
    23341 agatgatcag gtcattcgtc aacaggtcgg gaaaatgctc tctgaatggg gatttgaagt
    23401 ggtcctggta gaagacttta tggaagtttt gagtctattt gttcagtcgg aacctcatct
    23461 ggtcctcatg gatattggtt tgcccttgtt taatggttat cactggtgtc aggaaatccg
    23521 caagatttcc aaggtaccta tcatgtttct ttcttcgaga gaccaggcta tggatattgt
    23581 catggcaatc aatatggggg cggatgactt tgtgaccaag ccttttgacc agcaggttct
    23641 tttagctaag gttcagggct tgttgcgtcg ttcctatgag tttgggcgtg atgagagttt
    23701 gctggaatat gctggtgtta tcctcaatac caaatccatg gatttacatt atcaagggca
    23761 agtcttgaat ttgaccaaga atgaattcca gattttacgc gtgttatttg agcatgcagg
    23821 caacatcgta gcacgtgacg acctgatgcg ggaactttgg aacagtgact ttttcattga
    23881 tgataatacc ctctctgtca atgtggctcg tttgcgtaaa aagttggagg agcagggatt
    23941 ggtaggattt atcgagacca agaaaggaat agggtacgga ttgaagcatg cttgattgga
    24001 aacaattttt tctagcctat ctgcgctccc gtagtcgtct ttttatctat ctgctttctt
    24061 tggcatttct tgtcttactc tttcagtttt tatttgccag tctaggaatt tacttcctct
    24121 actttttctt cttgtgttgc tttgtaacca tcttattttt cacttgggac atattggtgg
    24181 aaacgcaggt ctatcgccag gaacttctct atggagagag ggaagccaag tctcctttgg
    24241 aaatagcttt agcagaaaaa ttagaagcgc gtgagatgga actctatcag cagaggtcaa
    24301 aagcagaaag aaaactgacg gatttgctgg attactatac cttgtgggtc catcagataa
    24361 agacccccat tgcagccagt caactcttag ttgcagaagt ggtcgaccgc caactgaagc
    24421 agcagctaga acaggaaatt ttcaaaatcg actcctatac caacctagtt ttacagtacc
    24481 tgcgtttaga aagtttccat gatgatttgg tcttaaagca ggttcaaatt gaggacttgg
    24541 tcaaggaaat aattcgtaaa tatgctcttt tctttattca aaaaggctta aatgtcaatc
    24601 tacatgacct tgataaagaa atcgtgacgg ataaaaagtg gctgctagtg gttattgagc
    24661 aaatcatctc aaacagtctc aagtacacca aggaaggtgg tctggagatt tatatggatg
    24721 accaagagct ttgtatcaaa gatacgggaa tcgggataaa aaacagtgat gtcctccgag
    24781 tatttgaacg tggcttttca ggatacaatg gccgtttgac ccagcagtcc tctggacttg
    24841 gcctttatct atctaagaaa atttctgaag aactggggca ccagattcgt atcgagtctg
    24901 aggtcggaaa aggaacgaca gtgcggattc agtttgctca agtgaactta gtccttgagt
    24961 aaaaatagat gagaaaaagc ctccagattg gaggctttta tgctagacac ttatttctca
    25021 acgcgtgatt tgttggcgat atcagctagg atagcttgaa caaaattatc aactgagaca
    25081 gtttgtgttt ctttttggcc gtagcgacga acgttgactg tttcgtcttc catttctttg
    25141 tctccaacaa ttaattggta aggaatcttg ctggtttgtg aagcacggat cttgaactgc
    25201 attttttcat tgcgctcatc tacgtctgca cggacaccgc ggtcacggag tttcttggcc
    25261 acttcccaag cgtagtccac gtgtttttcg ttagatactg ggatgagggt tacttggtgt
    25321 ggtgccagcc atgttgggaa ggcccccttg tagttctcaa tcaagatagc tgtgaagcgt
    25381 tccatagttg agataacccc acggtggatc atgactggac ggtgatcttc gccatcagct
    25441 ccgatgtatt tgaggtcgaa gcgttctggc aacaagaaat caagttggat agtagaaagg
    25501 gtttcttctt ttccaagggc agttttaatc tggatatcca attttggtcc gtagaaggct
    25561 gcttcacctt cggcttcaaa gtagtccacg cccatttcat caagagctgc acgaagcata
    25621 gtttgggcat tttcccacat ctcatcgtta tcaaagtact tatgagtatc ttgagggtca
    25681 cgaagagaga ggcggaagcg gtagtcagtc aagttgaagt cttcataaac atcgataatc
    25741 aactgaaggg cacgttggaa ttcttcttgg atttgttctg gagtaacgaa taggtgaccg
    25801 tcgttgagtg acatttcacg tacacgttga aggccagtga gggcaccaga tttttcgtaa
    25861 cggtgcatca taccgatttc agcgatacgg attggcaatt cacggtaaga gtgaacatgg
    25921 tgtttaaaaa cttggatgtg gtgcggacag ttcattggac gaaggacaaa ttcttccccg
    25981 tcacccatgt ccatggttgg gaacatgtct tcttggtaat gatcccagtg accagaagtc
    26041 ttgtaaagct caacagaagc aagtggtgga gtgtagacgt gttggtagcc agaagccaac
    26101 tctttgttta cgatgtagcg ttccaattca cgacggatag tcgcaccatt tggcaaccag
    26161 aatggcaaac cttgtcccac ttcttgtgaa atcataaaga ggtcaagctc tttaccaagt
    26221 ttacggtggt cacgttcctt agcttcttca cgcatttgaa ggtagttttt caagtctttc
    26281 ttgtcaaacc aagctgtacc gtagatacgt tgcatcatag cgttgtcgct gtttccacgc
    26341 cagtacgcac cagctacatg gagaaggtgg aagatttgga tacgacctgt tgatggaacg
    26401 tgaggtccac ggcagaggtc tacatattca ccctgacgat agatagtcaa accgccttcg
    26461 tcttctgagt gttcttcaat caattccaac ttgtaagggt catttttgaa gatttcacgt
    26521 gcctcgtctt tagtcacttc ttcacgaata gatgggaagt tttctttgac gattttttgc
    26581 atttcttctt cgatacgagg aaggtcttcg ttagagattt gaccagctgt gttgtcagta
    26641 tcgtagtaga aaccatcttc gatggctgga ccaactccca agtgaatgtc tgggaaaaga
    26701 cgacgagctg cttgggcgaa caagtgagct gctgagtgac gcaagattgg aagggcatct
    26761 tcgtgatcag gtgtcacaat ttcgatgctt ccatcttcag tgatagcgcg agtagtgtcg
    26821 atgagtttgc cgttgaattt accagccaag gcttttttag ctagggaatt gctgatagat
    26881 tgggcaattt caaaagttgt tacgccagat tcgaattcac gaacagcgcc atctgggaaa
    26941 gtaatgttaa tcatgatgtt ctcctttttt attatttcat agtttctaag cattgatttt
    27001 ttatcagcag actacttccg agtcctaacg ttcaattgct tttctttatc agagaggaag
    27061 ttttccattt ccgtcagaat gtctatatcc aaacgttgag aaagttctaa tagccaccag
    27121 atattttctg aaagtttttg ttccagtgtg tagggtgttt catcatagta gcgtccttgc
    27181 tttgtcatca ccagtcattg gaaatttcca atatcattag ataaagccaa gaggtcttct
    27241 tctaccgtcc acttgaaatc atgatgctta acttccagtt cgtgataagc ttgtcggatt
    27301 gcccaactgc gctccactaa ttcttgcaac tccataatta gtatcctaat aaaaaaatgc
    27361 gacatcctcg aaaggacgtc gcaacgtggt tccaccttca tttatgtacc tcaaaagaga
    27421 gggacacctc tgatcggctc taacgtggcc accgttttat gttttcataa aaaactcaag
    27481 agtagtatca gtttagactt cctatgcgtt tccagcaacc acgcactctc tagtagaaag
    27541 ggactaagtg acttgtctct atggattatt atagcatgat tgtgagattt ttcaaggatt
    27601 ttgtgaaagt tttttgtttt tcattttttg tagaatatgc ttgatgctaa taccagaatc
    27661 catgccgacc agagcaactg tttcatagat tagcaagtaa attagtataa actcaccaaa
    27721 ggttatgata gtaaagtaaa agagcagtcc gttaccaact aaccatcaaa gtgagaaacg
    27781 gaaacggtag ctatagagta acgatataat caagattacc agaggtgtaa agaagagaag
    27841 attgtttata tagagttcct tgagtgtaag ggggtcagaa acaactagta agaacaactc
    27901 ataaagtggc caataaaaga ataatatgac cagatagtag gggagatggg aatagaatct
    27961 acgcatgata atcacctcgt tttaaaaaaa cagacaactt agatctcttg ctatgattat
    28021 tatagcatgt ttaaaacaag aaagtaaatt tgttgacaaa gaagattttt cttttcacta
    28081 gaatcatagt tagttttctt ggtagaaata ttttgataat aattaagcaa gactattgac
    28141 attgattatt aagagtgtca caattattgt aactaaaata attacaacaa gagaggtata
    28201 aaaaatgaaa ctagcagtta ttgcagcaaa tggacaagcg gggaaagcaa ttgttgaaga
    28261 agcagtcaaa cgaggacatg aagtaacggc tattgttcgt tctgaaaaca aaagtcaagc
    28321 tgagtctatt attaaaaaag atttatttga gttgacaaaa gatgatctta ctggatttga
    28381 tgctgttatt tcagcgtttg gtgcttatac accagatacg ctaccgctcc acagcaaatc
    28441 aatcgaacta tttaatcagc ttcttgctgg aacacagaca cgttttctag ttgtaggggg
    28501 agcaggaagt ctttatatag atgaaacaaa aacgacacga cttttagata cgtctgattt
    28561 tcctgaagaa tttaagtcac tagcaaaaga tcaagcggat gaattggatc ttcttcgtac
    28621 aaaaaataat ctcaactgga cttttgtcag tcctgctgta gattttattc ccgatggtga
    28681 aaaaacagga aactacattc tagcaggaga aatttttact actaatgaaa aaggaataag
    28741 ccagattagt tatgcagatt atgctattgg attggtagat gaacttgaaa aaggtcatca
    28801 tataaaagaa cgtatctctt tacttgaaaa ataataacta tgagagtatt aatgtttgac
    28861 agaaaattta aatcttggta aaatagggat tgtcgtaaag acaaataact tcttcttggt
    28921 tacaggcatg ccaacctgtc actcggatga agccaaataa aaaggagaaa catcatggca
    28981 atctcaaaag agaaaaaaaa tgaaatcatt gcacaatatg cacgtcacga aggtgataca
    29041 ggttcagtag aggttcaagt tgctgtcctt acttgggaaa tcaaccacct taacgaacac
    29101 atcaaacaac acaaaaaaga ccacgctact taccgtggat tgatgaaaaa aatcggtcgc
    29161 cgtcgtaact tgcttgcata cttgcgtaaa aacgacgtta accgttaccg tgagttgatc
    29221 aactctctag gacttcgtcg ctaattcaag atacaaatgc tgtcaaaagc acaaagcaaa
    29281 aataggaaaa ttgacgaaga aacttcagtt tctaggagat tttatctttt ttgccaagtg
    29341 cttaggccgt gttcaattga gcatatcttg ataatgaagc tactctaaat tgggtagctt
    29401 ttttgcgttg tcaccttacc tcgatatact caagtataat ctttggttac ggttcctagc
    29461 actgtaaggt aaaataaacc agcttttctc ccttcgggga gatttttttt gtttcactga
    29521 aagtttcgta cgatcttcgc ctcgtcgcct agtctataaa cgatttatct agcaagaatc
    29581 atgatgctaa gggcgtcaaa aatccgtatg aaaataggga aatgacacag tgttcgatga
    29641 gcacaaggag tttcatcttt ttcactagga ttttagcccg ggctcaaatc agctctctga
    29701 cttcagaggg cttttttatt gaggttttat cggtaacaat tttggagact acaaaaacct
    29761 caaacggtat cagctaatta caccataaag gtgcgcagtt actcggcttt tcaagccgag
    29821 tagctgtatg caagccccct agaagagccc actctttaca aagtaaagta tagtatgtta
    29881 tactttacat ggaagtagtc actgaattcc agttagaaat tactttgtaa ctacgttttg
    29941 aggaggagta aaatgctttc ctacgttcga cattacccac tagcgatagc taaattaatg
    30001 tgtctgtgct ctcctaaaat ctgctgattt attactgact aatacaggag gtttttttta
    30061 tgggacagac aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa
    30121 ttattttaat tattttattt gcacagctat cacagaataa acagaaatgg catatttatg
    30181 cggggcaata tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg
    30241 ttaatttcgt gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag
    30301 ggattcgctt tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa
    30361 gattagaaca aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt
    30421 ctggcggaga taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga
    30481 ccctcgtggc cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtaggg
    30541 tgttatcctc tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc
    30601 ccttagtatt cattctactt ggactataca tcatgtatga aaatggcacg atagagactt
    30661 ttctgatcgt gtagattttt ttgtttcact aggattttag cccgagctca aatcagctct
    30721 ctgattttca gagggctttt tcattgagta taaatggaca atcttaaagt tactctattg
    30781 tagagtggct tttgatttga ttaggagatt cttataaata tagtaaaatg aaataagaat
    30841 aggacaaatc gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt
    30901 actattctag ttccaatcta ctatataaat gaaaacctta gctgtttggc caaggttcat
    30961 ttcttctatg caagttcttc tcttttctta tctgggttcc agatgaagct tgcgataaag
    31021 ctaaagatga tggttaggat agcgaggata atagcaagga tgagggcagg gatgcggata
    31081 aaccaccaga gtggatttgg ttttttatca ttgtgccatt gtttcgtttc ttcgtccaga
    31141 cgttggaatt ctgtttgaat acgattggcg actgtttcaa tgccttcatc attcattttc
    31201 ttgatatctg agatatcgat tggatttcca aagttcatat cgacacgttc acggctaatc
    31261 aagcccttca aagtcatggg accggtgtag gtaaccggca tgatacggac cttggccatt
    31321 ttggcaatca gtgctgcgcc ccccttgaca tcgtttgagt ggcggctacc acttggaaac
    31381 atgatgagag agcggtcact ttttttgaga acgttgatag gatatttgat ggctgaggcg
    31441 ctgggatttt cacggtcgat gggaaaggcg ccacacatac gaatccacca accaaagata
    31501 cggttggtaa agagttcttt ttttgccata aagatgaact gttttggctt ggtcgcaaag
    31561 gccatataaa caggatccca ccaggtacgg tgaggcgcaa ctaaaatata attttcatct
    31621 tgattaggaa ttttatcagt attatgatag tgagcattgc cattgatgga ccataagagc
    31681 aatacaacta atccacgcaa ataagtataa aacatgcgat ctccttcgat tgttttcttg
    31741 ttattattat accttatcaa aggagggctg gcaaactttt cccttgacta gatacatatt
    31801 taggatgaaa ttagaattct gttaaaaaaa atgatataat agaatttatg gataaaaata
    31861 agattatggg attaacccaa agagaagtca aggaaagaca ggctgagggt ttggtcaatg
    31921 actttaccgc atcagccagt accagcactt ggcaaatcgt taaacgaaat gtctttaccc
    31981 tttttaacgc tttgaacttt gccattgctt tggctcttgc ctttgtgcag gcttggagca
    32041 atctggtctt ctttgctgtt atctgcttta acgctttttc tgggattgtg accgagctac
    32101 gagccaaaca catggtggac aagctcaatc tcatgaccaa ggaaaaggtc aaaaccatcc
    32161 gtgatggtca ggaagttgct cttaatcctg aagaattagt gctaggagat gtcattcgtt
    32221 tgtctgcagg agagcagatt cctagtgatg ccttggtttt ggaaggcttt gcggaagtca
    32281 atgaagccat gttaacggga gaaagtgatt tggtgcaaaa ggaagttgac ggcttacttt
    32341 tgtcaggaag tttcctagcc agtgggtcag ttttatctca agttcaccat gtcggagcag
    32401 acaactatgc tgccaaactc atgcttgagg ctaagaccgt taaacccatc aactcccgta
    32461 tcatgaaatc gctggacaag ttggctggtt ttactgggaa gattatcatt ccctttggtc
    32521 tggctctctt gctggaagcc ttgcttttaa aaggcctgcc tctcaagtca tccgttgtaa
    32581 actcgtcgac agctcttttg ggaatgttgc ctaagggaat tgcccttttg accattactt
    32641 cgcttttgac tgcagtgatt aagctaggtt tgaaaaaggt cttggtgcag gagatgtact
    32701 ctgttgagac cttggcgcgc gtggatatgc tctgtctgga caagacgggc accatcaccc
    32761 aaggaaagat gcaggtggag gctgttcttc cactgacgga aacttacggt gaagaggcta
    32821 ttgccagcat cttgactagc tacatggccc atagtgagga taaaaatcca acagctcaag
    32881 ccattcgcca gagattccaa ggtcaagtag tctatcctat gctctctaat cttcccttct
    32941 ccagcgaccg caagtgggga gccatggagt tagaaggttt gggaatagtt ttcttagggg
    33001 cacctgagat gttgctggat tctgaggtcc cagaagccag agaggccttg gagagaggtt
    33061 cacgtgtctt ggtcttagct ctcagtcagg agaaattaga ccatcacaaa ccacagaaac
    33121 catctgatat tcaggctcta gccttgctgg aaatcttgga tcctattcga gagggagcgg
    33181 cagagacgct gaactatctc cgttctcagg aagtggggct caagattatc tctggtgaca
    33241 atccagttac ggtatccagc attgcccaga aggctggttt tgcggactat cacagctatg
    33301 tcgattgttc aaaaatcacg gatgaggaat tgattgctct ggcggaggag acagcgattt
    33361 tcggacgtgt ttcccctcat caaaagaaac tcattatcca aacgctgaaa aaagcgggtc
    33421 atacaacggc tatgacaggg gacggggtta atgatatctt ggcccttcgt gaggcggatt
    33481 gttctatcgt aatggcggag ggagacccgg caacccgtca gattgccaac ctggttctct
    33541 tgaactcaga ctttaatgat gttcctgaga ttctttttga aggtcgtcgt gtggtcaata
    33601 acattgccca catcgctccg attttcttga taaagaccat ctactcattc ttgctcgcag
    33661 ttatctgtat cgccagtgct ttactaggtc ggtctgaatg gatcttgatt ttccccttca
    33721 ttccaatcca gattaccatg attgaccagt ttgtggaagg tttcccacca ttcgttctga
    33781 cttttgagcg aaatatcaaa cctgttgagc caaatttcct cagaaaatcc atgcttcgtg
    33841 ccctaccaag cgctctcatg gtcgtgttta gcgtcctgtt tgtgaaaata tttgggagta
    33901 gccaaggttg gtctgagtta gaaatctcaa ctctcctcta ttatctcttg gggtcaattg
    33961 gtttcttatc cgtatttaga gcctgcatgc catttaccct atggcgagtc ctattgattg
    34021 tctggtcagt aggaggcttc ctagccacag ctctcttccc aagaattcaa aaactgcttg
    34081 aaattgcaac cttaacagga caaacattac ctgtttatgg tgtcatgatg ttggtcttta
    34141 ccgtgatttt catcctgacc agtcgctatc aagccagaaa ataaagaaag gctgcaatct
    34201 gtggattgca gtttttttag gtacaagatt gccagtcgaa atgtggtata ataagaggta
    34261 atagagtttt ggaaagtgag agaagatgat ttcaaagaga ttagaattgg tagcttcctt
    34321 tgtgtcacag ggggctattt tactagatgt gggaagtgac catgcttatc tgcctatcga
    34381 gttggttgag agaggccaaa tcaaaagcgc tattgcaggt gaggtggtgg aaggtcccta
    34441 tcagtctgcg gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc aagtccgttt
    34501 agccaatggc ttggcagctt ttgaagagac tgaccaagtg tctgtcatta ccattgctgg
    34561 catgggtggt cgtttgattg ctaggatttt agaagaaggt ttggggaagt tagctaatgt
    34621 agagcgtttg atcctccagc ccaataatcg tgaagacgac ttgcgtatct ggctacagga
    34681 tcatggattc cagattgtag cagaaagcat cttagaagaa gctggaaagt tttatgagat
    34741 tttggtggtg gaagcaggac aaatgaagct atcagccagt gatgttcgct ttggtccctt
    34801 cttgtccaaa gaagtcagtc cagtatttgt ccaaaaatgg caaaaagaag ctgagaagct
    34861 agagttcgcc ctcggacaaa tcccagaaaa aaatctggaa gaacgtcaag ttctagtaga
    34921 taagattcaa gctatcaagg aggtgctcca tgttagcaag tgaagtgatc caagcttatg
    34981 aagccttttg ccctcaggaa ttttctatgg agggagacag ccgtggtctg caaattggca
    35041 ctttagacaa gggtatccaa agggtcatgg ttgccctcga tattcgtgaa gagacagtgg
    35101 cagaggccat tgaaaagggt gtggacttga ttatcgtcaa gcacgcgcct atctttcgtc
    35161 ctatcaagga cttgcttgcc agccgtccgc aaaatcagat ttacatcgac ctgattaagc
    35221 atgatatcgc agtttatgtc agccatacca atattgatat cgttgaaaat gggctcaatg
    35281 actggttttg tcagatgcta ggaatcgagg agacgactta tctgcaggaa acaggtccag
    35341 aacgtggaat tggacgtatt gggaatattc agcctcagac attttgggaa ttggcccaac
    35401 aggtcaagca agtctttgac ctagatagcc ttcgaatggt gcattatcaa gaggatgatt
    35461 tgcagaagcc tatttcaaga gtagcaattt gtggtggaag cggacagtct ttctataagg
    35521 atgctttggc aaagggggca gatgtctata tcactggtga tatctactac catactgctc
    35581 aggatatgct gtctgatggc ttgttagcat tggatccagg tcactatatc gaagtgcttt
    35641 ttgtggaaaa aatcgcaaca ctccttactc aatggaaaga gaaaaaaggc tgggaactag
    35701 agattttacc tagtcaagca tcgaccaatc ctttccgtca tatctagtta gaaagtgaag
    35761 acaatgaaaa aagttgccat tattggagca ggaattgtgg gagcaacagc tgcctactac
    35821 ctctcgagag aaagtgacct agaggtgacc gtttttgacc atgagcaagg tcaagccacc
    35881 aaggctgcag caggaattat cagtccttgg ttttccaaac gccgtaataa agcctggtac
    35941 aagatggcgc gcttgggggc tgatttttat gtggatttat tagctgattt agagaaatca
    36001 ggacaaaaaa tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa ggatgaatcc
    36061 aagttggaag aactttatca actggccctc cagcgcagag aagaatctcc cttgataggg
    36121 caattagcca ttctggacca agcctcagct aatgaattat tccctggttt gcagggattt
    36181 gaccgcctgc tctatgcttc tggtggagcg agagtagatg gccacctctt agtgactcgt
    36241 ttgctggaag ccagtcaggt caagctggtc aaagaaaaag tgactctgac accgttagca
    36301 tcaggctacc agattggtga agaggagttt gagcaggtta ttttggcgac gggagcttgg
    36361 ttgggggaca tgttagaacc cttgggttat gaagtagatg ttcgtcctca aaaaggacaa
    36421 ctacgagatt atcagctggt ccaagacatg gaagcttacc ctgttgtcat gccagaaggg
    36481 gagtgggatt tgattccttt tgcaggtggg aaattgtcct taggcgctac ccacgaaaat
    36541 gacatgggat ttgatttgac ggtagatgaa accttgctcc aacaaatgga ggaggccacc
    36601 ttgactcact atctgatttt ggctgaagct acttcaaaat ctgagcgtgt gggaatccgt
    36661 gcctatacca gtgatttctc tcccttcttt gggcaggtgc cagaattggc aggtgtctat
    36721 gcagccagtg gactaggttc atcaggcctc acaactggtc ctatcattgg ttaccatcta
    36781 gcccaactga tccaagacaa ggagttgacc ttggaccctc taaattaccc aattgaaaac
    36841 tatgtcaaac gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca aactaggtaa
    36901 ctagccgcgg gttactcaaa gcactg
//
LOCUS       DBEJNA010000022        36081 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEJNA010000022 DBEJNA010000000
VERSION     DBEJNA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.22"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            264..1070
                     /gene="pnuC"
                     /locus_tag="ACL3JB_001203"
     CDS             264..1070
                     /gene="pnuC"
                     /locus_tag="ACL3JB_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0685934.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(1236..1772)
                     /gene="sczA"
                     /locus_tag="ACL3JB_001204"
     CDS             complement(1236..1772)
                     /gene="sczA"
                     /locus_tag="ACL3JB_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR0685935.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKDYETTTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            1905..2795
                     /gene="czcD"
                     /locus_tag="ACL3JB_001205"
     CDS             1905..2795
                     /gene="czcD"
                     /locus_tag="ACL3JB_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0685936.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            3039..3392
                     /gene="nmlR"
                     /locus_tag="ACL3JB_001206"
     CDS             3039..3392
                     /gene="nmlR"
                     /locus_tag="ACL3JB_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0685937.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            3393..4430
                     /locus_tag="ACL3JB_001207"
     CDS             3393..4430
                     /locus_tag="ACL3JB_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR0685938.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(4476..5483)
                     /gene="galR"
                     /locus_tag="ACL3JB_001208"
     CDS             complement(4476..5483)
                     /gene="galR"
                     /locus_tag="ACL3JB_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0685939.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAI
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            5647..6825
                     /locus_tag="ACL3JB_001209"
     CDS             5647..6825
                     /locus_tag="ACL3JB_001209"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0685940.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGSGLSSSASLEILTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            6844..8325
                     /locus_tag="ACL3JB_001210"
     CDS             6844..8325
                     /locus_tag="ACL3JB_001210"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0685941.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLSRVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIARNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            8395..8799
                     /locus_tag="ACL3JB_001211"
     CDS             8395..8799
                     /locus_tag="ACL3JB_001211"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0685942.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            8980..9744
                     /locus_tag="ACL3JB_001212"
     CDS             8980..9744
                     /locus_tag="ACL3JB_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR0685943.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            9741..10202
                     /locus_tag="ACL3JB_001213"
     CDS             9741..10202
                     /locus_tag="ACL3JB_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR0685944.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(10253..11515)
                     /locus_tag="ACL3JB_001214"
     CDS             complement(10253..11515)
                     /locus_tag="ACL3JB_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0685945.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(11515..12096)
                     /locus_tag="ACL3JB_001215"
     CDS             complement(11515..12096)
                     /locus_tag="ACL3JB_001215"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0685946.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(12496..12591)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(12974..13213)
                     /locus_tag="ACL3JB_001216"
     CDS             complement(12974..13213)
                     /locus_tag="ACL3JB_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR0685947.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(13213..13356)
                     /locus_tag="ACL3JB_001217"
     CDS             complement(13213..13356)
                     /locus_tag="ACL3JB_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR0685948.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(13368..14195)
                     /locus_tag="ACL3JB_001218"
     CDS             complement(13368..14195)
                     /locus_tag="ACL3JB_001218"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0685949.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            14329..14784
                     /locus_tag="ACL3JB_001219"
                     /pseudo
     CDS             14329..14784
                     /locus_tag="ACL3JB_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            14937..15233
                     /locus_tag="ACL3JB_001220"
     CDS             14937..15233
                     /locus_tag="ACL3JB_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0685950.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            15439..17184
                     /locus_tag="ACL3JB_001221"
     CDS             15439..17184
                     /locus_tag="ACL3JB_001221"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685951.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            17174..18925
                     /locus_tag="ACL3JB_001222"
     CDS             17174..18925
                     /locus_tag="ACL3JB_001222"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685952.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            19098..19790
                     /locus_tag="ACL3JB_001223"
     CDS             19098..19790
                     /locus_tag="ACL3JB_001223"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0685953.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            19833..21059
                     /locus_tag="ACL3JB_001224"
     CDS             19833..21059
                     /locus_tag="ACL3JB_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0685954.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            22190..24349
                     /gene="pfbA"
                     /locus_tag="ACL3JB_001225"
     CDS             22190..24349
                     /gene="pfbA"
                     /locus_tag="ACL3JB_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0685955.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            24333..24629
                     /locus_tag="ACL3JB_001226"
     CDS             24333..24629
                     /locus_tag="ACL3JB_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685956.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            24801..25184
                     /locus_tag="ACL3JB_001227"
     CDS             24801..25184
                     /locus_tag="ACL3JB_001227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685957.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASIVVIDV"
     gene            25242..25883
                     /locus_tag="ACL3JB_001228"
     CDS             25242..25883
                     /locus_tag="ACL3JB_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR0685958.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            25896..27371
                     /gene="galT"
                     /locus_tag="ACL3JB_001229"
     CDS             25896..27371
                     /gene="galT"
                     /locus_tag="ACL3JB_001229"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0685959.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            27384..28363
                     /gene="galE"
                     /locus_tag="ACL3JB_001230"
                     /pseudo
     CDS             27384..28363
                     /gene="galE"
                     /locus_tag="ACL3JB_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
     gene            28573..29232
                     /locus_tag="ACL3JB_001231"
     CDS             28573..29232
                     /locus_tag="ACL3JB_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0685960.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTIVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            29257..30324
                     /locus_tag="ACL3JB_001232"
     CDS             29257..30324
                     /locus_tag="ACL3JB_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0685961.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            30427..31437
                     /locus_tag="ACL3JB_001233"
     CDS             30427..31437
                     /locus_tag="ACL3JB_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685962.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            31449..33140
                     /locus_tag="ACL3JB_001234"
     CDS             31449..33140
                     /locus_tag="ACL3JB_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685963.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            33143..33853
                     /locus_tag="ACL3JB_001235"
     CDS             33143..33853
                     /locus_tag="ACL3JB_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0685964.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            33949..34317
                     /locus_tag="ACL3JB_001236"
     CDS             33949..34317
                     /locus_tag="ACL3JB_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685965.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            34425..35426
                     /locus_tag="ACL3JB_001237"
     CDS             34425..35426
                     /locus_tag="ACL3JB_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0685966.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    35638..35867
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        11308 a         5977 c         7704 g        11092 t
ORIGIN      
        1 ttttttgatg tgagaatgac tgaatgtcac ttaaaatgga aagaaagaga aaattttcat
       61 gattttctaa aattttactg taaagacagt tgactattca taaaataggt gtataatatt
      121 ttgtgaacta cttaacaaat aagaggtttc agctcatgtc gactaaggtt agaaatcttg
      181 tgtataggca gttcattatc taatagagcg ttgcgtccga aagtctatcc agacacggct
      241 ctttaaaaac aaaaggagaa atgatgcata cttatttgca aaagaaaatt gaaaatatca
      301 aaacaaccct aggtgaaatg tcaggtggtt accgtcgtat ggttgcggct atggctgatt
      361 taggattttc aggaactatg aaggctatct gggatgacct ctttgcccat cgtagttttg
      421 cccagtggat ttatttgctg gttttaggaa gttttcctct ctggctggag ttggtttacg
      481 aacatcgtat tgttgactgg attgggatga tttgtagctt gacagggatt atctgtgtaa
      541 tctttgtatc ggaaggtcga gcaagtaatt atctttttgg cttgattaac tctgttattt
      601 accttatttt ggccctacag aaaggctttt atggtgaggt gctgacgaca ctttacttca
      661 cagtcatgca gccaattgga cttctagttt ggatttatca ggcacagttt aagaaggaaa
      721 agcaggagtt tgtcgcgcgt aaactggacg gaaagggctg gacaaagtat ctttccatta
      781 gtgtgctttg gtggttggcc tttggcttca tttatcagtc tattggtgcc aatcgtccct
      841 atcgtgattc aatcacagat gcaaccaatg gggtagggca aatcctcatg acagctgttt
      901 accgtgaaca gtggatattc tgggcggcta ccaatgtttt ttcaatctat ctctggtggg
      961 gagaaagcct gcaaattcaa gggaaatatc taatttatct cattaacagt ctagttggtt
     1021 ggtatcaatg gagcaaggca gctaagcaga atactgattt acttaactag gaaaagatgt
     1081 ttgaaagtgc tgttttgaga tttcgattaa aacagatata gttgataatc aaggatttat
     1141 agtatgaaaa agaggatcgg cgggtcctct tttgttgttg aaaagataaa aaactcagta
     1201 acctagaaat aagacaactg agctttactc tatattcaat ttttaggaat gagaaggtct
     1261 agataaaatt ggacaacttc ctggtctgtg aaatcttgac cttttttgag ccaccaggtc
     1321 aatgtctcga taaagttgga catgaccaag tgttggaggt aagaagtagg cagattaggg
     1381 tgggcttctt ttaaattatc agctagcacg gaatagacgt ggtgctcaag ctctctctgg
     1441 agttgacgga ggaagtagtc atttttggaa aatagcagac tggtgatatg gtcttggttt
     1501 ttatgaaaat ggagaaagag gtgggcgagg tagtcctcag ttgaaatggc ttgctctctt
     1561 tcaaaaagat gatggaagag gtagcggcag agctgatcca gaagaagctc tttactctca
     1621 tagtgacagt aaaaggtgga tcgtcccaca tctgcgagat caatgatatc ctgaacagta
     1681 gtggtctcgt agtccttagc attcaaaagt tgtataaaag cttgatagat ggcttttttg
     1741 gttttgctga tacggcggtc aatgttagtc atatggacac ttgaggcaaa ttgttcagaa
     1801 ctgaataaag ctgacgtttt gcttctatcc tttctttgag ttttagtgga taatgataat
     1861 gaacaaggtg ttcataaatc tattataaca aaggaatgag aaatatgaag gcaaaatatg
     1921 ctgtttgggt ggcttttttc ttaaatttga cttatgccat tgttgagttt attgcaggtg
     1981 gagtatttgg ttctagcgct gttcttgctg actctgtgca tgacttggga gatgcgattg
     2041 caattggaat atcagctttt ctagaaacaa tctccaatcg tgaagaagac aatcagtaca
     2101 ccttgggcta taagcggttt agcctgctag gagccttggt aacagctgtg attctcgtaa
     2161 cgggctctgt tctagtcatt ttggaaaatg tcacgaagat tttgcatccg caaccagtca
     2221 atgatgaggg gattctctgg ttaggaatta ttgcgattac tatcaatctg ttagcgagtc
     2281 tggtggttgg taagggaaag acaaagaatg agtctattct gagtttgcat tttctggaag
     2341 atacgctagg gtgggtagct gttatcctga tggcgattgt tcttcgattt acggactggt
     2401 atatcctaga tcctcttttg tcccttgtca tttctttctt tattctttca aaagcccttc
     2461 cacgtttttg gtctacactc aagattttct tggatgctgt gccagaaggt cttgatatca
     2521 agcaagtaaa gagtggcctg gagcgattgg acaatgtggc cagccttaat cagcttaatc
     2581 tctggactat ggatgctttg gaaaaaaatg ccattgtaca tgtttgtcta aaagaaatgg
     2641 aacatatgga aacttgtaaa gagtctattc gaattttcct aaaagattgt ggttttcaaa
     2701 atattaccat tgaaattgat gctgacctag aaactcacca aacccataag cgaaaggtgt
     2761 gtgacttgga acggagttat gagcatcaac attagaaaaa agtgaaaaat acttgggtac
     2821 tatcttattt ggaatagagt aatttcttta ttatttaaat atttcaaaaa ttggtaagag
     2881 aagagcattg tataaactcc agatatatga ttgttaatga taaaaatttt tcgattagat
     2941 acaaaatgct tgacttggag tcaactcaaa gttatataat aagataagtg agttagaata
     3001 gcgtgaattc agtgaatgaa atgagaggag gttagcgtgt gaatattaaa tctgccagtg
     3061 atttgttggg aatttcagcg gatacgattc ggtattatga acgggttggt cttgtgccac
     3121 cgattactcg tactgctact gggattcgtg attttcaaga tcaggatatc gaagcgctgg
     3181 aatttattaa gtgttttcgt tcggcgggtg tctctgtaga tagtttagtt gactatatgt
     3241 cgctctacca aaagggagat gaaacgagag aggagaggct tggtatttta gaagaggaaa
     3301 agcaaaaatt agaggagcgc ttgtctcagc tacagacagc tttaaatcgt ttaaatctca
     3361 aaattaaact ttataaggaa ggaaaatttt aaatgaaatc agcagtatat acaaaggcag
     3421 gtcaggttgg acttgctagc attgaacgtc cgcaaataat agaagcggat gatgtgatta
     3481 ttcgtgtggt tcgtgcgtgc gtttgtggtt cagatttatg gaggtaccgt aatccagaaa
     3541 cgaaagctgg acacaaaaat agtggacacg aagcgattgg gattgttgaa gaagctgggg
     3601 aagccattac gacggtgaaa ccaggtgatt ttgtgattgt cccttttaca catggatgtg
     3661 gtgagtgtga tgcctgtctt gctggatttg acggttcttg cgacaatcat attggcaata
     3721 atttgggggg tgattttcag gcagaatata ttcgcttcca ctatgcaaac tgggcgctgg
     3781 ttaaaatccc tggtcaacct tctgactata cagaagggat gctcaagtcc cttttgactc
     3841 ttgcagatgt catgccgaca ggctatcatg cggcgcgtgt tgcaaatgtt caaaaagggg
     3901 acaaggttgt tgttatcggt gatggggctg ttggtcaatg tgctgtcatc gcggctaaga
     3961 tgcgtggagc atcacaaatt atccttatga gccgtcatga agaccgtcaa aagatggcta
     4021 tggagtcagg tgcgacagct gttgttgcag aacgtggtca agaaggaatt accaaggtgc
     4081 gtgaaatcct cggtggagga gcagatgcag cacttgaatg tgttggtacg gaggctgcta
     4141 tagaacaggc gctaggtgtt cttcataatg gagggcgtat gggctttgta ggagtcccac
     4201 actataataa tcgtgctctt ggttcgacat ttatgcaaaa tatctctgta gcaggtgggg
     4261 cagcttctgc tacaacatac gataagcaat ttttactaaa agccgtcctt gatggtgata
     4321 tcaatccagg tcgcgtcttt acttcaagtt ataaactgga agatatcgac caagcctata
     4381 aagatatgga tgaacgtaag acaattaagt ctatgattgt aatcgaataa aaaacgaata
     4441 ggagttttag aactctattc gttttttatg ttatcctatt cttgatttag ggtactttct
     4501 cttaatgtca gtctggttcc cagcatggtc aggctaggga ttttccgacc gtggaggact
     4561 tccttgttaa gaatatccat acctgctcgc cccatttctt cagtataaac tgtgatgctg
     4621 gagaggggag gataaacctg cttggtcagg ctggtgtcgt taaaggaaat gaggctgaca
     4681 cggtctggta ggctgattcc agcttcttgg agcgcacgaa gggcaccgat ggctaaacta
     4741 tcgctggctg cgaaaaatgc tggtgggagt tggtctccca agttctgaat ggcttccttc
     4801 atcaagtcat agccagactg ggcagtaaag tttccttgaa agatcagttc atcatgatag
     4861 attccttttg cttgactgta gtttctgaaa ttttccagcc gcttatcctc aatgatttct
     4921 tcttggtcag ttgtttcttc aaggcctgtt agaatcccga tacggtccat tccttggctg
     4981 aggaaataat cgacaacctg ttttatggca gtgtaaaagt ccgtaataat gcaggtatgt
     5041 cccagggaaa gtgtatcact gtctagaaag accaggggtt tttggtattc ttcaaaggca
     5101 gaaatctgag ctcggctaaa ttttccgatg cagagaatcc caatcacttc ctcgcttaag
     5161 gtaaaaggat ggtcattaaa atagcgcaag atatcatagt ccaactcttg ggctcttttt
     5221 tctattccta ggcgaatctg gtagtagtag aggtcgtcca gctccccttg ttcgctgacc
     5281 cattgaataa tggcaatctt ttgcttgggt ttatgggact cgcctgtctt gaggtgcttg
     5341 gtgtagccca gctcttcagc aacggttaaa atacggtgtc tggtttcttc tgtaacagat
     5401 aggctctggt cgcggttgag gacgcgggat acggtcgcga tagagacaga ggctagctgt
     5461 gcaatgtctt ttaaggtagc cataaatcct ccttgattag gttagtatat catatttttc
     5521 tgctttttac tgatagttta gtaaaatttt agtaaaaagg attgaccttg ggaaatccct
     5581 tggatacaat agaagaaaac gattacacgt taaggtggct taacggacag tcaaaggaga
     5641 aatcatatga cacaacatct tactgctgaa actcttcgca aagactttct tgctgttttt
     5701 ggtcaagaag cagaccaaac tttcttttca ccaggccgta ttaatttgat tggtgaacac
     5761 acagactaca acggtgggca cgtttttcca gctgctattt ccttaggaac ttatggtgca
     5821 gctcgcaagc gtgatgacca agtcttgcgt ttctactcag ctaactttga ggacaagggc
     5881 ataattgaag tgcctctcgc tgacctcaag tttgaaaaag agcacaactg gaccaactat
     5941 ccaaaagggg ttcttcattt cttgcaagaa gctgggcacg tgattgacaa aggttttgat
     6001 ttttatgttt atgggaatat cccaaatggt tctggcttgt cttcttcagc atccttggag
     6061 atcttgacag gagtcgtggc agagcatctc tttgatttaa aactagagcg tctcgatttg
     6121 gttaaaatcg gaaaacaaac agaaaataac tttatcggag tcaactctgg tatcatggac
     6181 cagtttgcta ttggtatggg ggctgatcaa cgtgctattt accttgatac caacacctta
     6241 gagtatgatt tggtgccact tgatttgaag gacaatgtcg ttgttatcat gaacaccaac
     6301 aaacgccgtg aattggcgga ctctaaatac aatgaacgtc gtgctgagtg tgaaaaagca
     6361 gtggaagaat tgcaagttgc cttggatatt cagaccctgg gtgaattgga cgagtgggcc
     6421 gttgaccaat atagctatct gattaaagat gaaaatcgtt tgaaacgtgc tcgccatgct
     6481 gtgcttgaaa accaacgtac ccttaaagct caagcagccc ttcaagcagg tgatttggaa
     6541 acatttggtc gtttgatgaa tgcgtcacac gtttctctgg agcatgatta tgaagtaact
     6601 ggtttggaat tagataccct tgttcacaca gcttgggcac aagaaggagt tctcggtgct
     6661 cgtatgacag gggctggttt tggtggctgt gccattgcct tggttcaaaa agatactgtt
     6721 gaggccttta aggaagctgt aggcaaacac tacgaggaag tagttggata cgctccaagc
     6781 ttctatatcg ctgaagttgc aggtggcact cgcgtccttg actagtcaaa aggaggctct
     6841 atagtgacct tagtagataa atttgtaaca catgtcattt ctgaaagttc atttgaggaa
     6901 atggatcgaa tctacctgac caaccgtgtt ttgtcacgag tgggagaagg tgttttggaa
     6961 gttgagacca atctggataa attgattgac ctcaaggacc agctagttga ggaaaccgtt
     7021 cgattagaga cgattgagga tagtcagact gcgcgtgaaa tccttggtac tgaattgatg
     7081 gacttggtga ctccttgtcc gagtcaggtc aatcgtgact tctgggaagc ctatgcctac
     7141 tctcctgagc aagcgataga ggatttttat caactcagtc agaaaaatga ctacatcaaa
     7201 ctcaaggcca ttgctagaaa tatcgcttat cgtgttccat ctgactacgg agaacttgaa
     7261 attaccatca atctctctaa gcctgaaaaa gatcccaaag agattgtggc agccaagttg
     7321 gtgcaagcta gtaattatcc tcagtgtcag ctttgtctag agaatgaggg ctaccatggt
     7381 cgagttaacc acccagctcg tagcaatcac cgtattatcc gttttgaaat ggttggtcag
     7441 gaatggggtt tccagtattc gccctatgct tactttaatg agcattgtat ctttttagat
     7501 ggccagcatc gtcccatggc cattagtcgt cagagttttg aacgtctgtt ggctatcgta
     7561 gaccagtttc caggatattt tgctggatct aatgccgacc tgccgattgt ggggggctct
     7621 attctaactc atgatcatta tcagggaggc cgtcacgtat ttcctatgga attggctccc
     7681 ttgcaaaagg ccttccgatt tgctggtttt gagcaggtca aggctggaat tgtcaagtgg
     7741 cccatgtctg tcctacgttt gacttcggat tccaaagagg atttgatcaa tttggctgat
     7801 aagattttgc aggaatggcg tcagtattca gattctagtg tgcagatttt agcagagaca
     7861 gacgggacac cgcatcacac catcacacca atagcgcgta agcgtgatgg acagtttgag
     7921 ttggacttgg tcttgcgaga caatcagact tcagcagagc atcctgatgg catctatcat
     7981 ccccacaagg atgtccaaca tatcaagaag gaaaatatcg gcttgattga ggtcatgggc
     8041 ttggcaatct tgccaccacg tctgaaagaa gaagtagagc aagtcgctag ctatcttgta
     8101 ggagaagctg ttacagttgc cgattatcat caggagtggg cagaccaact caaatcccaa
     8161 catccagacc taacggataa agaaaaagcc cttgcaatcg tcaaggactc tgtgggtgct
     8221 atctttgtgc gtgtacttga ggatgcagga gtctacaagc agacagaaca agggcagaca
     8281 gcctttatgc gctttgtgga acaggtcgga attttactag actaggagct ttctccttgc
     8341 acagtcctat aaaaagtagt atcatagtgt cgtttgaaat atcaggagga aacgatgaaa
     8401 gactttcatt ttgacgctat atctgccttt gaaaattacg aaattgaaaa aatgagagat
     8461 ggtcacgttg tggtgacgac caaagtagtg aactcatcgc tcaactacta tggcaatgcc
     8521 catggtggct atctattcac gctatgtgac caaatcagtg gtttggtggt tatctcgctg
     8581 ggacttgatg gggtgacact ccaatcctct atcaactacc ttaaggcagg aaaactcgac
     8641 gatgtattga ccattaaagg agaatgtgtc catcaaggtc gtacaacctg tgtgatggat
     8701 gtggatatca ccaatcaaga gggcagaaat gtctgtaagg caacctttac catgtttgtc
     8761 acaggccaaa ggtctgagga aagacgggta agtatataaa gaaaggtgag tgggataaat
     8821 ttatctcact catttttaat ttatgagata tgttagaagg aaatataaaa gagagtgatg
     8881 aaatacaaat gtaataggta catatatgtg gtatactagt tatagtagat tttaattgct
     8941 tatatcgagt gagttctcat attagtgagg aatttttaaa tggaattaca ctttaattta
     9001 gaattagtag aaacctataa aagtaatagc caaaaggcac gtatcttaac ggaggattgg
     9061 gtttatcgtc agtcttattg ccctaattgt gggaacaatc ccttaaatca ttttgaaaat
     9121 aatcggcctg tagcagattt ttactgtaat cattgtagtg aggagtttga actaaagagc
     9181 aaaaaaggaa atttttcatc aacaatcaat gatggtgctt atgcaacgat gatgaagcgt
     9241 gtgcaggcag ataataatcc taatttcttt tttttaactt acacaaaaaa ttttgaggta
     9301 aataactttc ttgtccttcc gaagcaattt gttacaccga aatcgattat tcaaagaaaa
     9361 ccacttgcac caactgctag acgagcaggt tggattggtt gtaacattga tttatcacaa
     9421 gtaccttcta aaggaaggat atttcttgtg caagatggac aagttagaga tccagaaaaa
     9481 gttacaaaag aatttaagca aggtttattt ttaaggaaga gctctctgtc atcaagaggt
     9541 tggacaatag aaattctaaa ttgtatagat aagatagagg gttcagaatt tacccttgaa
     9601 gatatgtatc gttttgaaag tgacctaaaa aatatctttg ttaagaacaa tcatatcaaa
     9661 gaaaagatta ggcaacagct tcaaatatta agagacaaag aaataataga atttaaaggt
     9721 agaggaaagt atcggaaatt atgaaaacga aacaacttgt tgcatcagaa gaggtgtatg
     9781 atttcttaaa agtcatctgg cctgattatg aaactgaaag ccgttacgat aacctaagtt
     9841 taatcgtctg taccttatca gatcccgatt gtgtgagatg gttatctgaa aatatgaaat
     9901 ttggtgacga aaaacaacta gctttgatga aggaaaaata tgggtgggaa gtaggagata
     9961 aattgccaga gtggctacat agctcctatc atagattatt gttaataggt gaattattgg
    10021 aaagcaatct aaaactgaaa aagtatacag tagaaattac agaaacttta tcacgtttag
    10081 taagtataga ggctgaaaat ccagatgaag ccgaacgact tgtaagagaa aagtataaga
    10141 gttgtgaaat tgttcttgat gcagatgatt ttcaggacta tgacactagc atatatgaat
    10201 aggtagatgt ttttattttg tcacacaaaa aagaggctcg cacctctttt tcttatttct
    10261 ttttatgatt taatacggca ttgaggacaa tagcgagtag gctggctacg acgattccgt
    10321 ttgagaagaa catttggaag gctgtcggca tgctgacaaa gagattactg ttgttgagac
    10381 cgacacctgc agcgattgaa acagctgcga taaggaagtt gtgttcattg ttagcaaagt
    10441 caactcgggc gaggatttgc atcccttgaa tagatacaaa accaaacatc accagcatgg
    10501 caccgccgag gacggagctt ggaatgattt gggcaagggc accaaactta ggaagcagtc
    10561 caaggagaac caggaaacca gctgcgtagt agattggcag gcgttttttg atgcctgaca
    10621 atttaaccaa accaacgttt tgtgaaaatc cggtgtaagg gaaggtgtta aagattcctc
    10681 cgagaagtac cgccaaacct tctgcgcggt aaccgttgcg aaggcgcgtg ctgtcgattg
    10741 gatcttttgt gatatcagac aaggctagat aaacaccagt tgactcaacc atagacaccg
    10801 ttgcgatgat acacatcatg acaatagatg agatttcaaa ggttggcatc ccaaagtaga
    10861 gtggagttgg gacatggaca agtggagcta ccgcaacagg agagaagtcc accaagccca
    10921 tagtagcagc aatggcagtt ccaacaacca gaccaatcaa aatagagata gacttgataa
    10981 atcctttggt aaagatgttg atcaagagga taatcagaac agtaatagct gcaagcaaga
    11041 gactttgacc agttggctct ggaacgttat ttcccatatt tccaatagcg acagggatca
    11101 aggttaaacc aatcgtggta ataacagatc ctgttacgat agatgggaag agattggcta
    11161 cttttgagaa gatgcctgaa acaagaacca cgtaaatccc agatgcgata agggcaccaa
    11221 acatagcgcc actaccatgg ctttgcccaa tcataatcaa gggagcgacc gactggaatg
    11281 caactccaag aacgactggg agtccaatcc caaagtattt gttgagttgg agttggagga
    11341 aggttgccac cccacacatg aagatatctg tagaaatcag gtaggtcaac tgctcagctg
    11401 aatagccaag ggctgtcgca atcatgatgg gaaccaggat agatcctgag tacatggcta
    11461 gtaagtgctg caagcccaga acggctgctt gcgagtgttt ttcttgagtt tgcattagag
    11521 atctgcctcc ttaaatacga cctgaccatt ttcaaaacga tccaagcgag caagtgatag
    11581 gacagggtag cctgcttttt caagcaaatc acgaccatct tggaaggatt tctcaatcac
    11641 gataccgata gcttggactg tggcaccggc ctgttcgatg atttgaatca agcctttagc
    11701 agcttggcca ttagcaagga aatcgtcgat aatcaaaacc ttgtcctctg gtgagaggaa
    11761 ttttccagcg atagaaacag tgctggtcac ctgcttggta aaggagtaga cttgagcagt
    11821 taagatgcct tcgttcatgg tgatgttctt agcttttttg gcgaaaatca tgggaacgtt
    11881 taaggcttca gctgtaaaaa cggctggggc aatacccgac gcttcaatgg ttacgacctt
    11941 ggtaatgcca gtagcagcaa atttttccgc aaaaacctta ccaatctctc gcatcaagct
    12001 aaagtcaact tggtgggtta aaaaggaatc taccttgagg atgttatcac ccaagatatg
    12061 cccatccttg aggatgcgct cttctaataa tttcataaga cctcctaaag tctaaaagtt
    12121 aatttacttg ttgtttaaat atttctatag tgatcccttt tgctaatact atatatttga
    12181 taaaactatt acgagcgaag cgagtcttat caaatatttc ccgttgtagt ggtatcatag
    12241 acaataatct tgttattgtc tatgacggga tttttgagag taaaatagtt cggggaacta
    12301 ttttagccta agcctagaaa tgaaagagct aggggctcaa aaattaggga tgaaattccc
    12361 tggattcctg aaattattca caggataatt tcacctcccg tccgcactaa ttaagggaaa
    12421 tattaaaaat attcaaaaaa gacctactta atctctaagt aagtccccta aatagacatg
    12481 gcaaaaacgg ccatatctca ctgctgactt acttattgtt aggtgttccg gcaccttgta
    12541 gaaacgtcgt gccaattcac gacataaaca agtaaaacga tattcaattt taaataggct
    12601 tgagccaatg tttttatttt acactaaata actttagaaa tcaactattt tgttagtatt
    12661 ttggtttaaa aagcgaacaa aaagaagaga gggtgaacaa aaactccatt gtaagctaac
    12721 atttatacta aatgaaaatc aaagagcaaa ctaggaagct atccacaacc tcaaaacact
    12781 gttttgaggt tgtggataga attgacagag tcagtatcat atacctacgg taaggcgacg
    12841 ttgacgtggc ttgaagagat tttcgaagag tattagaaga tttttccatc ataaaaggca
    12901 tactatcaag tttttaaaca cctgacaata tgcctttttc taactttaaa gacttttccc
    12961 aatttttatt attctactcg ctaaatctta aaaaatagcc atctggatcc aaaactgcaa
    13021 atttatgagg atagatatag ggatcactga cacgaaactt tcttttggtc aagggacgat
    13081 aaataggata gtttgcctcc atcacttttt gatagagttt tggaacatcc tttatgccaa
    13141 aggagagatt gactccacga ccaaaggggt aggtcagttc agctagttga tcctttgttc
    13201 cctcctctaa cattagttga cactcttcaa gagaaagaga aagttttctt ctggacgttg
    13261 gtattcaatc ctaaaaccca gtaaaccaca gtagaaggac cgggactgtt cgatattcga
    13321 tacaagaaac tcgggaatga ccgcattgta gtccatatag aaaatcctta caagtcaatt
    13381 tccaagacaa tcggtgtatg gtcttggcga gcacctgagt caatcatatc agatttagtg
    13441 accttgtcag cgatacggtt acttgtgagc cagtagtcga ttctccagcc tgtattgttg
    13501 attttagaag ttttgctgcg ttgtgcccac caagtgtagc gttcaggaac atcgccatga
    13561 acatggcgga aggtatcagt aaatccagtt gccaataggt tggtaaatcc agcacgttcc
    13621 tcgtcagtaa atccaggtga acggcggttg ctagcaggat ttgcaaggtc gatttcattg
    13681 tgggctacgt tgtagtcacc ggtcgcaagg actggttttt ctttgtctag ttcagccaaa
    13741 tactccgcat atttgacatc ccagacttgg cgttcttcca agcgtttaag accatcgcca
    13801 gcatttggtg tgtaaacttg ggtcacgaaa aatgcatcaa attctagagt gatgatgcgg
    13861 ccttccaagt ccatggtaga aggggcaccg atttctggga aagtgacagt gggtgtaagt
    13921 tctttcttat aaaggaacat ggttccagca tagcctttac gggcaggctc ttgggaagag
    13981 cgccacgtgt tttcgtagcc tgggaagagt tcttctaaaa tttccacgtg tttctttgta
    14041 ggtcctttgg cagaaagctt ggtttcttgg atagcaatga tatcagcatt ttcagcgacc
    14101 aaggtttgta ggacttcttg ggacaatttg gcacgagctg agtcactagt tagggcagcg
    14161 tttagggaat caatattcca tgagataagt ttcataaagt tacctttttc attcagatta
    14221 tagattttat tataccaaaa aaagatctat ttccccaacg tatggtttga aaaattactc
    14281 tctttcgttt ataattaaga atgattttat gaaagggagt gaaaatacat gaaattctac
    14341 tcttatgact atgtactcag ccaaatcggt cagcaaaatg gtatcatggt tggctttggg
    14401 attgttctat tagctgtgac agtttttttg cttttaaggc ataccatgat aaaaagggaa
    14461 ccgaatttcg tgagttggtc atgatttcag ctctggcctt atttagctct gcttttggtc
    14521 agcatcacga cttatcaaaa caatcaagtt tctaacaata aatttcaaac ttcacttcat
    14581 ttcatcgagg ttgtttccaa agatttggga gtagacaagt cagaagtcta tgttaatact
    14641 tccacaaaca cagatggcgc acttatcaag gtgggagatc gctattatcg tgccctaaac
    14701 ggaagtgagc cagacaagta cctgttagag aaagtcgaat tgtataagac agacgcaatt
    14761 gaactggtgg atgtgaacaa atgacactta attatatcga aattttaatc aaactggtct
    14821 tgactctcaa atagttcaac aacaatgttc actttatgaa acgtttgatt gatggtaagc
    14881 caactctcct tatcaaaaat gggaatattg acccataagc ctgtcgttca gttggtttgt
    14941 ctgcatcgga tgtagccctc aaacttcgta gccaagggat tttccagatg aagcaagtca
    15001 aacgagctgt gcaagagcaa aatgggcaac tcatcgttgt gcaaatggga gatgaaaatc
    15061 ctaagtatcc agttgtgact gacggtgtga ttcaagtaga tgtcttggaa tcgattggtc
    15121 gtagcgaaga gtggttgctt gataacctca gcaaacaagg gcatgacaat gtagccaata
    15181 tctttattgc tgaatatgac aagggtgctg ttacagtcgt aacttatgaa taagaaaaac
    15241 ctggggtctt gtactcttcg aaaatctctt caaaccgcgt caacgtcgcc ttgccgtatg
    15301 taggttactg acttcgtcag ttctatctac aacctcaaag cagtgctttg agcagcctgc
    15361 ggctagtttc ctagtttgct ctttgatttt cattgagtat tggcctcagg cttccatttg
    15421 caatcagaaa gggattttat gtccattatt caaaaacttt ggtggttttt caagttagaa
    15481 aaacgccgtt atctagtcgg gattgtggcc ctggtcttgg tttccgtcct caatctcatt
    15541 cctcctatgg ttatggggcg ggtcattgat gccatcacat cggggcaatt aacccagcag
    15601 gacctccttc ttagcctatt ttacttgcta cttgcagcct ttggtatgta ctatttgcgc
    15661 tatgtgtggc gtatgtatat ccttgggacc tcttattgct tgggacagat catgcggtct
    15721 cgcttgttta agcatttcac aaaaatgtcg tcagcctttt atcaaaccta tcggacgggt
    15781 gatctgatgg cacacgcaac caatgatatc aatgccttga ctcgtttagc aggtggcggt
    15841 gtcatgtctg cggtggatgc ctctatcacg gctctggtga ctttgttgac catgctcttt
    15901 agcatctcat ggcagatgac tcttgttgcc attctccccc tacctttcat ggcctatgcg
    15961 actagtcgcc tagggagaaa gactcataag gcctttggcg aatcccaaac tgctttttct
    16021 gaactcaata acaaggtaca ggagtccgta tcaggtatca aagtgaccaa gtctttcggt
    16081 tatcaggcag acgagttgaa gtcttttcag gcagtcaatg aattaacctt ccaaaagaac
    16141 ctgcaaacca tgaaatatga tagtctcttt gaccctatgg ttctcttgtt tgttggttcg
    16201 tcctatgttt taacgctttt ggttggctcc ttgatggttc aggaagggca gattacagtt
    16261 gggaatctag tcacctttat cagctatttg gatatgctgg tctggcctct tatggccatc
    16321 ggcttcctct ttaatactac tcagcgaggg aaggtttctt accagcggat tgaaaatctt
    16381 ttgtctcagg aatctcctgt acaagacccg gagtttcctc tggatggtat tgaaaatggg
    16441 cgtttggagt atgccattga cagctttgct tttgaaaatg aggaaacact gacggatatt
    16501 cactttagtt tggcaaaagg gcaaacactg ggcttggttg ggcagacagg ctctgggaaa
    16561 acgtccttaa tcaagctcct cttgcgtgaa tacgatgtgg ataagggcgc catttatcta
    16621 aacggtcacg atattcggga ctatcgtctg acagaccttc gcagtctcat gggctatgtt
    16681 cctcaggacc agtttctttt tgcgacttca atcctagaca atatccgctt tggcaatcct
    16741 aacttgcccc tttcagcggt cgaggaagct actaagctag cccgagttta ccaagatatt
    16801 gtagacatgc ctcaaggatt tgatacgctg attggtgaaa aaggagtcag tctttctggt
    16861 ggtcaaaagc aacggttggc tatgagtcgg gctatgattt tagaccctga tatcttgatt
    16921 ttggatgatt ccttatccgc cgtagatgcc aagacagagt atgcgattat cgacaacctc
    16981 aaggagacgc gaaaggacaa gacaaccatt atcactgccc atcgcctgag tgcagttgtc
    17041 catgcagatt tgattttagt cctgcaaaat ggtcaaatta tcgaacgagg caggcacgaa
    17101 gacttgctag ctttggatgg ctggtatgcc caaacctacc agtctcagca gctggaaatg
    17161 aagggagaag aagatgcaga ataaacaaga acaatggact gtattgaagc gcttgatgtc
    17221 ctatctcaag ccttatggac tccttacctt tttggcactc agttttctcc tagcgacgac
    17281 ggtcattaaa agtgtcattc cccttgtggc ttcccacttt atcgaccagt atctcagcaa
    17341 tcttaaccaa ctagccgtga ccgttttgct ggtctactat ggtctctaca tcctacaaac
    17401 tgtagttcag tatgtcggca atcttctctt tgcgcgcgtg tcttacagta ttgttaggga
    17461 tattcgtcgg gatgcctttg ccaatatgga gaaactgggc atgtcttact ttgacaagac
    17521 gccagcaggt tctatcgttt ctcgtttgac caacgatacc gagacgatta gtgatatgtt
    17581 ttctgggatt ttatccagct ttatctcagc agtttttatc tttctgacaa ccctttatac
    17641 catgttggtg ctggattttc gtttgacagc attagtcttg ctctttctcc ccttgatttt
    17701 ccttttggtc aatctctatc gaaaaaagtc agtgaaaatc atcgagaaaa ccagaagtct
    17761 cttgtcagat atcaatagta agctggcaga gaatatcgag ggaatcagga ttattcaggc
    17821 ttttaatcaa gagaagcgcc tgcaggcaga atttgatgaa atcaaccaag agcacttggc
    17881 ctatgccaac cgttctgtag ccttggatgc cctctttttg agacctgcca tgagtttgtt
    17941 gaaacttcta ggttatgctg tcttgatgac ctattttggc tatcgtggtc tttctatcgg
    18001 gataacggcc gggaccatgt atgcttttat ccagtacatc aaccgcctct ttgacccttt
    18061 gattgaggtg acgcaaaact tttcaacact gcaaacgtct atggtttctg caggccgtgt
    18121 ctttgcctta atcgatgaga ggacctatga gccccttcaa gaaaatgggc aagccaaagt
    18181 caaagaaggc aatatccgtt ttgaacatgt gtgtttctcg tatgacggta aacatccgat
    18241 tctggatgac atttctttct ctgttaataa gggtgaaacc attgcctttg taggtcatac
    18301 aggttcaggg aaatcgtcta ttatcaatgt cctcatgcgc ttttatgaat tccagtcagg
    18361 gagagttctc ttggatgatg tggatatcag ggatttcagt caagaagagc tgagaaaaaa
    18421 catcggtttg gttttacagg aacccttcct ctatcatgga actattaagt ccaatatcgc
    18481 catgtaccaa gaaatcagtg atgagcaggt tcaggctgcg gcagcctttg tggatgcaga
    18541 ttcctttatt caagaacttc ctcaggggta cgactcccct gtttccgagc gtggttcgag
    18601 cttctctact gggcagcgcc agcttcttgc ctttgctaga acagtcgcca gccagcctaa
    18661 aatcctgatt ttggatgaag cgacagccaa tattgactct gaaacagaaa gtttggttca
    18721 agcttctctg gcgaagatga gacagggccg aacaactatt gctatcgctc accgcctttc
    18781 tactattcaa gacgccaact gcatctatgt cttggataag ggacgcatta tcgagagtgg
    18841 aacccatgag gaactcttga ctctgggagg aacctatcac aagatgtata gtttgcaggc
    18901 aggggccatg gcctatactc tttgaaaatc tctttaaacc atgtcagctt tatctgcaat
    18961 ctcaaagctg tactttgatt ttcattgagt actagaagga aatccttcaa attacagatt
    19021 tctttcaccg ccttttccat tttgtggtat aatgaaaaat gttgacaaat agtataataa
    19081 aaacaaagga gaacagcatg ctgaaatggg aagacttgcc tgtggaaatg aaatcaagcg
    19141 aggttgagtc ttactaccag cttgtctcta aaaggaaggg ttcgctgatt ttcaagcgtt
    19201 gcttggactg ggttttggcc ttggtcttac tggttctaac ttctcccatc tttctcatct
    19261 tgagcatttg gatcaagttg gatagcaagg ggccagtgat ttacaagcaa gagcgtgtga
    19321 cccagtacaa ccgtcggttc aagatttgga agttccgtac catggtgacg gatgcggata
    19381 aaaaaggaag tctggtgact tctgctaacg atagccgtat taccaaggtt ggaaatttca
    19441 tccgacgtgt ccgtttggac gaactgcctc agttggtcaa tgtccttaaa ggtgagatgt
    19501 cctttgtcgg tacacgacct gaagtgccac gttatacaga gcagtatagc cctgaaatga
    19561 tggcaacctt gctcttgcaa gcaggaatta cctctccagc cagcatcaac tacaaggatg
    19621 aggacaccat catcagtcaa atgacggaga aaggtctgtc agttgatcag gcctatgtgg
    19681 agcatgttct tcctgaaaag atgcgctata acctcgccta tctccgagag tttagtttct
    19741 ttggggacat caaaatcatg tttcaaaccg tgtttgaggt actaaaataa agtagtcata
    19801 agaaaatgag tacagataaa aggagcaaat caatgccaaa ttacaatatt ccattttcac
    19861 cgcctgatat cacagaagca gaaattgctg aagtagcgga taccctgcgt tctggttgga
    19921 tcacaacagg tcctaaaaca aaagaactgg agcgccgctt gtctctttac acacagacac
    19981 ctaagactgt ttgtctcaac tctgcgacag ccgctctgga gttgatttta cgcgttttgg
    20041 aagtgggacc tggtgatgaa gtcatcgttc cagccatgac ctatacggct tcatgtagtg
    20101 tcattacgca cgtgggagca acccctgtca tggtggatat ccaagcagat acgtttgaga
    20161 tggactatga cctgcttgag caagctatca ctgagaaaac taaggtgatt atcccagtag
    20221 agctcgcagg gattgtttgc gattatgacc gtttgttcca agtcgtggag aaaaaacgtg
    20281 acttctttac cgcttcaagc aagtggcaaa aggcctttaa ccgtattgtc attgtctctg
    20341 atagtgccca cgctttggga tctacttata aaggacaacc ttctggttct atcgctgatt
    20401 ttacttcctt ctcattccat gctgttaaga actttacaac ggcagaaggt ggaagtgcga
    20461 cttggaaagc caatccagtg attgatgacg aagagatgta caaggaattc caaatccttt
    20521 cccttcacgg gcaaactaag gatgctcttg ccaagatgca actggggtca tgggaatacg
    20581 atatcgttac accagcctat aagtgcaaca tgaccgatat catggcttca cttggtttgg
    20641 tacaattgga ccgctatcca agtttgttgc aacgccgtaa ggacattgtg gaccgctatg
    20701 atagtggttt tgcaggttct cgcatccatc ctttggcaca caagactgaa actgtcgaat
    20761 cttcacgcca cctctacatc acccgtgtag aaggagcaag cctagaagaa cgcaacctca
    20821 tcatccaaga attggctaaa gcaggaattg caagtaatgt tcactacaaa ccgcttcctc
    20881 tcttgacagc ctataagaat cttggatttg atatgacgaa ctatcctaag gcctatgcct
    20941 tctttgagaa tgaaattacc ctccctcttc atactaaatt aagcgatgaa gaagtagact
    21001 atatcattga gactttcaaa acagtttctg aaaaagtgct aactttatca aaaaaatgac
    21061 aaactacagt caagcgaaag tgatcctgtc cctaaaaagt ctaattgagt gtaaaaactg
    21121 ttgttttcaa ttgataatag tttacacctg tagttgaggc ctctttctcc tcagagagag
    21181 aatttttata ggattttcct ttcttgtggg agtcccgtgg tttgaaataa gatgtgagca
    21241 atttggtata gcatttagaa tccttactag acatcattta gaaaatctag tgtcttgttc
    21301 tagttttcaa ttcaccctat tttttgaaag acgtgagttt ccatgagtga gattgtggaa
    21361 actagcgtct tttttttgtt ttcagaatat tgttcaaagt tttgtgcctg tctttcatgt
    21421 tctagtcatt cttttgcatg atagaattta tagcatgttg atattataat aacgcaaata
    21481 tcccatatgt ttagtgatgc ttgctataca tcattagatc tcctgcgaga caatctataa
    21541 aacacttgtc tacgattacc tatatgccct attccagtat tttagaagca ctgcatctat
    21601 ttttatcgag gttaaatcta gcttttatag aaggtctatt taagaaatat attgtagtgt
    21661 tttagtttca atccgccata tgagcgatat tcaggtaaat atccctggcg aatgcttgta
    21721 tgacaaggta tttgttcttt catttataat ttacaacata tcaacaaatt taaatatagt
    21781 aaatgggata ttttatattc aagctaagaa agatagcatc acttttgaat ggaaggctaa
    21841 agagcaaact aggaagttgg ccatagatag ctcaaaaccc tgctttgagg ttgtagatat
    21901 agtaaaatga aacaagaata ggacaaattg atcgggacag ttaaatcgat ttctaacaat
    21961 gttttagaag tagaggtgta ctattatagt ttcagtctac tatagaactg accaagtcag
    22021 taacctagac ttagggcaag gcggcactga cctagtttga agagatttcc gaagagtata
    22081 aattttaata ttttcttgtg ttattccttg acaattcaat ttggaaaata tatgataaaa
    22141 ataatgacag cggtgtcatt ctatctattt taagaaaagt aataatcaat tgttaaaaat
    22201 agtaaaaaaa ttggaggttc tgatgaaata ttttgttcct aatgaggtat tcagtattcg
    22261 taaattaaag gtggggactt gctcggtact attggcaatt tcaattttgg gaagccaagg
    22321 tattttatcg gatgaagttg ttactagttc ttcaccgatg gctacaaaag agtcttctaa
    22381 tgcaattact aatgatttag ataattcacc aactgttaat cagaatcgtt ctgctgaaat
    22441 gattgcctct aattcaacca ctaatggttt agataattcg ttaagtgtta atagtatcag
    22501 ctctaatggt actattcgtt ccaattcaca attagacaac agaacagttg aatctacagt
    22561 aacatctact aatgaaaata agagttataa ggaagatgtt ataagtgaca gaattatcaa
    22621 aaaagaattt gaagatactg ctttaagtgt aaaagattat ggtgcggtag gtgatgggat
    22681 tcatgatgat cgacaagcaa ttcaagatgc aatagatgct gcagctcaag ggctaggtgg
    22741 aggaaatgta tattttcctg aaggaactta tttagtaaaa gaaattgttt ttttaaaaag
    22801 tcatacacac ttagaattga atgagaaagc tacaattcta aatggtataa atattaagaa
    22861 tcacccttcc attgttttta tgacaggttt atttacggat gatggtgcgc aagtagaatg
    22921 gggcccaaca gaagatatta gttattctgg tggtacgatt gatatgaacg gtgctttgaa
    22981 tgaagaagga actaaagcaa aaaatctacc acttataaat tcttcaggtg catttgctat
    23041 tgggaattca aataacgtaa ctataaaaaa tgtaacattc aaggatagtt atcaagggca
    23101 tgctattcaa attgcaggtt cgaaaaatgt attagttgat aattctcgtt ttcttgggca
    23161 agccttaccc aaaacgatga aggatgggca aatcataagt aaggagagca ttcagattga
    23221 accattaact agaaaaggtt ttccttatgc cttgaatgat gatgggaaaa aatctgaaaa
    23281 tgtgactatt caaaattcct attttggcaa aagtgataaa tctggggaat tagtaacagc
    23341 aattggcaca cactatcaaa cattgtcgac acagaacccc tctaatatta aaattttaaa
    23401 taatcatttt gataacatga tgtatgcagg tgtacgtttt acaggattca ctgatgtatt
    23461 aatcaaagga aatcgctttg ataagaaagt taaaggagag agtgtacatt atcgagaaag
    23521 cggagcagct ttagtaaatg cttatagcta taaaaacact aaagacctat tagatttaaa
    23581 taaacaggtg gttatcgccg aaaatatatt taatattgcc gatcctaaaa caaaagcgat
    23641 acgagttgca aaagatagtg cagaatattt aggaaaagta tcagatatta ctgtaacaaa
    23701 aaatgtaatt aataataatt ctaaggaaac agaacaacca aatattgaat tattacgagt
    23761 tagtgataat ttagtagtgt cagagaatag tatattcggt ggtaaagaag gaattgttat
    23821 tgaggattca aagggtaaaa taaccgtttt aaataaccaa ttttataatt tatccggtaa
    23881 gtatatatca ttcatcaaat ctaatgcaaa cgggaaagaa cctgttatac gtgatagcga
    23941 tggtaatttc aatattgtaa cggagaatgg gctttacaaa attgtaacaa ataatttaag
    24001 tgataaaaac gaaaaagaaa aaaacaaaga ggaaaaacaa tctaattcaa ataatgtaat
    24061 tgatagtaac cagaagaacg gagagtttaa ctcaagtaaa gataatagac aaatgaatga
    24121 caagatcgac aataaacaag ataataagac agaagaagta aactataaaa tagttggaga
    24181 tggcagagaa actgaaaatc atattaataa atctaaagaa atagtagatg taaaacaaaa
    24241 attaccaaag actggttcga acaagattat ggaactattc ttaacagtga caggaattgg
    24301 tttacttttg acactaaaag ggttgaagta ttatggtaaa gataaataaa atttgttcga
    24361 tacaaggaag ttccgtagaa aatgaggata ttgtaggttc acaaaatcag tatttttgga
    24421 ttattggtgg agctacagat ttatataatt ctaaagagga gataggttat tcagtctcag
    24481 aagttgtaca tattttatca gaaagtttgt cggttaattg taaagaatca aaaactctta
    24541 aacaaatatt tgaaactgct ttactcgagg ttaaagatga aatcggttta aactcatatg
    24601 aattaacaga gtataataaa atgaaataat aataggacaa atcaatcagg acagtcaaat
    24661 cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat atactatatt
    24721 atcgcttacc aacatttgct tttatatttg ctaaactttc agaaaaaaag ttggagtata
    24781 tgatgctagg tgactgcgtc atgttagtaa acgaaatgga aataacggat catagagtag
    24841 ataacttatt tgaaaaaggg aaaaatgaga taaaagatcc aattggtaca aatagtgttt
    24901 taaataaaaa aattatttta caaaaaatca gaaaattatc taatcaaccg agtgggtact
    24961 ggataggttc gttggatgag agatttttag accatgctat tattaatcaa atagatgtta
    25021 ctagtgaaca aattgtttta atgagcgatg gcttttatga attctatcaa aataatcaaa
    25081 ataaaacttt tgaagagtta attaagatga gatttaattc ttctgctatt gatccaatct
    25141 atggaaagaa agatgatgca agtattgtag ttattgatgt ttgatatatt gtttaaaata
    25201 ttaattgtta ctattgaact ttgttaagaa gaggtaccta aatgttaagg ttatatttag
    25261 aaaatgaaat tatagaatta tcaaataatt tagagaccat ttgggtatct gtgcttgata
    25321 aatatgagaa gttatttgaa tatttatcaa atgaagaacg aatagaattg attaaagaag
    25381 atttaatcat aaatgagtca gttctaaatg ttgataaaaa aggatatgag ttaatttgtt
    25441 tacaacatcc cgtttcatat gacttaagaa gaattattag tgtaataaaa atatcaactg
    25501 acattgaacg tattggggat agaattgttg aaattttaaa aaatctacag attcttcaaa
    25561 ataatgaaat tttgaagaaa attatttcag aaataaaaat acttcatgaa gttatcggac
    25621 tgcatatgaa tagggctata tcttgttata gagaggaaca atctggatgt ttagatatgg
    25681 ttgttataca aaaacagaat gagatagaag agcttagtac aaatattgaa aagaaaataa
    25741 tgaattacat atttgaagat gatgggaatg tttctgaagt aattggtgct ttagatatta
    25801 ttcatcacct tgataaaatt gctcatacta cgcaatcaat ttataaatgg ataatgtata
    25861 gaaaatatgg gaacataaat tagaaagaaa aatatatgaa aacaattatt gataattttg
    25921 ttgatagagt aattgaatac ggaatgtata atgaaattga caaaatatat gtgaaaaata
    25981 gagtactagc gttaataggt gaggagggaa ctgatcgcat ttccgatgaa aatgacctga
    26041 aacaaataaa agattactta gtggaaatcg ccttaaaaaa cggtaaaatt aaagatttaa
    26101 tcgaggaaaa ggaatgttta ggagcagagt taatgaattt catagttcct ttacctagtc
    26161 gattaaatga tattttttgg agttcatatg atatatcacc tcaagaagca gttgaagagt
    26221 tttataagtt aagtaaagat agtgattata ttaaaacttc tgctattgct aagaatattg
    26281 agtttcgagc atcaactaaa tacggagagc tagagattac gataaatttg tcaaaacccg
    26341 aaaaagatcc aaaaacaatt gctgctgaaa aattagtaaa agccactaat tatcccaaat
    26401 gtttactatg tatggaaaat gaaggatatc aggggcgaat aaattatcca gcacgttcga
    26461 atcatagaat tattcgattg aaacttggtg acgaagtatg gggattccaa tattctccct
    26521 acttatactt taatgagcat gcgatatttt taaatagtca acatgtacca atggctatta
    26581 cctctaaaac atttgaacaa ttattggaga ttgttgatat tttgccagga tattttgctg
    26641 gttcaaattc tgatcttcct atctcaggag gctccattct tagtcataac cactaccagg
    26701 gagggaaaca tattttccca atggaaaaag caaaatttga gagtgaattt cgttttaaag
    26761 actttgagga tgttaatgct ggtattgtaa aatggccaat gtcagtaatt aggttacaaa
    26821 gtgaaaataa aaatcgcttg ttagatttag ctactaaaat tctaaataag tggagagaat
    26881 attcagattt agaagtagac atcattgcta tgactgaaga tgtcccacac catacggtga
    26941 ctcctattgc tcgtaaagtg gacgggagat atgaattaga tattgttcta agagataatc
    27001 atactactga acagtaccca gatggtgttt tccatcctca tcaagatgta caacatatta
    27061 aaaaggaaaa tatcgggtta atcgaagtga tgggacttgc gatattacca cctcgtttga
    27121 aaccagagtt agaagaagtt ggaaaatatc ttttaggaga ggataacgca attgcggatt
    27181 atcatttaga atgggccgac caattgaaag aaaaatatcc tcgcattaat aaagaagagg
    27241 ttaatagcgt agttcaacac gaagcaggac aagtgtttgc gagagttctg gaagatgcag
    27301 gagtttataa gaatacaccg tctgggcatg aagcgtttat gagatttgtt aagtcggttg
    27361 gaattaatta ggaggaaaca aaaatggcaa tattggtaac aggcggagct ggttatattg
    27421 gtagccatac cgtagtagaa ttactaaatt taggaaagga agtcatcatt gtcgacaacc
    27481 tttcgaactc tagcatcttg gtgctagacc gtattgaagc aattacagga atacgtcccg
    27541 tgttttacga attagatgtt tgtgataaac cagcattgag aaaggtattt gaacaagaat
    27601 cgattgatgc tgcaattcat tttgcaggtt ataaagctgt cggagaatcc gtgcaaaagc
    27661 ctgtgatgta ctacaaaata atattatgag tacattggca cttgttgaag tgatgtcaga
    27721 atttaatgtt aaaaagattg tcttttcttc aagtgcgact gtatatggaa ttaacaatca
    27781 gtcacctcta attgagacta tgcaaacaag tgcgacaaat ccttatgggt atacgaaagt
    27841 gatgcttgag caaattttaa aagatgttca tgtggcagat tcagaatgga gtattgcgtt
    27901 gcttcgttat ttcaatccaa ttggtgctca tgagtctggt ttgattgggg aagatccctc
    27961 aggaattcct aacaacttga tgccctatat tgcacaagta gcggtaggta agctgtcaga
    28021 actaagtgtg ttcggaaatg attatgatac gcttgacggt actggtgtgc gcgattatat
    28081 ccatgtagta gatttagcaa taggacatat aaaagcttta gaaaaagtat ctgaaaaaac
    28141 agatgtttat atctataacc taggctcggg agaaggcact agtgtattac aacttgtaaa
    28201 tacatttgaa agtgttaata agatccctat tccttataaa atagttccaa gacgttcagg
    28261 agacgttgca acttgttatg caaatgcaga caaagcatat aaggaattaa attggaggac
    28321 aacaaaatcg attgaagaca tgtgtagaga tacatggaat tagcaatcaa aaaatcccaa
    28381 tggctataat tgatgatact gtctatatga gtgctgtatt ttggaaaaat tacttaacct
    28441 tttaatgaaa tgcatattta atgaaagata aattaaaaaa aatgtttgac agcgcttgac
    28501 aaaggaaacg gtttcattgt ataatgtaaa catagtgaca ccgatgtcaa atataaaaaa
    28561 gaaggtcttt atatgaaaaa cttaacaaaa attaagttca aagagaatgg ggaatttaat
    28621 catttccctg ggaatacaat tgtagcaaat ctttatacta aacaagattt gatggaagtt
    28681 gttgatatta ttcaatcacg ttatagagaa ttaccattta tcgataagtt tactttaact
    28741 ccaaggaatt ctattcacat gactgtaatt gaattgttgt gccatgaaaa tcgtgaaacg
    28801 gagttttgga gcagtaatct tcctctagat acacctttac aggaaataca tgattacttt
    28861 gctaaacaac ttgaaatttt tccattgttg gatgaagaaa ttcatatgcg tataactgaa
    28921 atgggaaaac aaaacatact agttgaacct gcagatgaag cttctgcaaa gagattagaa
    28981 gaaattcgta cttatgtctc agaaaaagca ggtgtttgtt tccctaatca tgatagatat
    29041 caattccata tttcaattgg gtatcttcgg attcctctaa ccgaagagga ggaagaagag
    29101 tttactaaag tcagagcaga attaactgaa attttattag agaagattcc aactattact
    29161 gtaaaccgta ttgactatac tgtatttgaa gatatgagac aatttgttcc atatcacgaa
    29221 aaatttaaat aaaataataa aaaaggagaa cttatcatga aaaaaatgaa agtttggtct
    29281 actgtacttg caacgggagt tgctcttact acacttgctg cttgctctgg aggttcaaat
    29341 tctacgactg cttcttcatc tgaagaaaaa gctgataaaa gtcaagaatt agtaatctat
    29401 tcgaactcag tctcaaatgg tcgtggtgat tggttaactg ctaaagcaaa agaagctggt
    29461 tttaatataa aaatggttga tattgctggc gctcaattag cagaccgtgt tattgctgag
    29521 aagaataatg cagttgcaga tatggtattt ggaattggtg ctgttgactc aaataaaatt
    29581 agagatcaaa aattactagt acagtacaag cctaaatggt tagataaaat tgatcaatct
    29641 ttatcagata aagataatta ttataatcct gtgattgttc aaccattagt tttaattggg
    29701 gcgcctgatg taaaagaaat gcctaaagat tggactgaat taggtagtaa gtataaaggt
    29761 aaatattcaa tttatggtct tcaaggtggt acaggacggg caattctagc aagtatctta
    29821 gttcgttacc ttgatgaaaa aggagattta ggcgtatcag aaaaaggatg ggaagttgca
    29881 aaagaatact ttgcaaatgc ctatactctt caaaaaggtg aaagctcagt tgttaaagcg
    29941 ttagataaag aaagcccaat tcaatacggt atgatctggg gttctggagc gttaatcgga
    30001 caaaaagaac aaaatgttga attcaaagtt atgactcctg agattggtgt accatttgta
    30061 actgaacaaa ctatggtttt aagcactagt aaaaaacaag cgttagctaa agaatttatt
    30121 gattggtttg gtcaatcaga aattcaagta gaatatagta aaaaatttgg atctattcct
    30181 gcaaataaag atgccctaaa agagttacct gaagatacga aaaaatttgt tgatcaagtg
    30241 aaaccacaaa atattgactg ggaagctgtt ggaaagcatt tggatgaatg ggtagaaaaa
    30301 gctgaattag aatacgtaaa ataagaaata agagttattt tttatgtcca agtctctcta
    30361 ttatttctaa atttaaggaa gaaataaaga gaggcttttg gtttagtaat agagggagtt
    30421 agtgagatga ttaaatttga taatattcaa attaaatatg gtgattttgt tgcaattgat
    30481 aatctgaatt tagatataca tgaaggggaa ttctttacat ttcttgggcc ttcaggatgt
    30541 ggtaaatcaa ctactttgag agcattggta ggttttttag atccatcatc aggaagtatt
    30601 gaagttaatg gaacagatgt cactcatttg gaacctgaaa agcgtggaat tggtattgta
    30661 tttcaatctt atgcgctatt tccaactatg actgtttttg ataatattgc atttggttta
    30721 aaagttaaga aggtagctcc agatgttatt aaagctaaag tatcagcagt ggcagcaaaa
    30781 attaagatct ctgatcaaca gttacagcgt aatgtatcag aattatctgg gggtcaacaa
    30841 caaagggtag cattggctcg tgctctggtt cttgaaccta aaattctttg tctagatgaa
    30901 ccattgtcaa accttgacgc aaaattacgt gtagatttga gaaaagagtt gaaaagactt
    30961 caaaaagagt taggtattac tactttatat gttactcatg atcaagagga agccttgact
    31021 ttatctgata gaattgcagt ctttaacaat ggatacatcg aacaggtcgg tacaccagta
    31081 gagatttatc ataattctca aactgaattt gtatgtgatt ttattggaga tattaatgtt
    31141 ttgaccgatg aaacagtcca cgaagtatta ctgaaaaata caagcgtttt cttagaagat
    31201 aaaaaaggat acattcgatt agagaaagtt cgattcaatc gtgaaactga acaagatttc
    31261 attctaaaag ggacaattat tgatgttgag ttttctggag ttacaattca ctatacaata
    31321 aaagtttctg aaagtcagat tcttaatgta acaagtattg atagtcaggc tgctattaga
    31381 tctgtcggag aaagtgtgga attatttatc acaccatcag acgttctgca attttaagga
    31441 ggtgcagtat gcgtcataaa ttaaatttaa aagattggct tattcgttta gggttaatct
    31501 ggttcttagt aacatttatt atttatccaa actttgatct agtagtgaat gtatttgtaa
    31561 aaggaggaga attttccctt gatgctgtac atcgtgttct aaaatctcag agggcacttc
    31621 agagtattat gaacagtttt aagttagcat tttcactcat tattacagtt aatgtcgtag
    31681 gtattctttg tgttctattt acagagtact ttgatattaa aggtgctaaa attttaaaat
    31741 taggttatat gacctcttta atttatggag gagtggtttt agcgactgga tataaatttg
    31801 tctatggtcc atatggattg attacaaaat ttttacaaaa tgttatccct tctttagacc
    31861 ctaactggtt tattgggtat ggtgcagtct tattcattat gacattttca ggaactgcta
    31921 atcatacatt gtttttaaca aatacaattc gaagcgttga ctatcacact attgaggctg
    31981 ctcgaaatat gggagcaaaa ccatttactg ttttccgaaa agtagtgtta ccaaccttaa
    32041 ttccaactct atttgcactt actattatgg tttttcttag tggtttatct gcagtagcag
    32101 cacccatgat tgttggtggt aaagaatttc aaactataaa tccaatgatt attacatttg
    32161 cagggatggg gaattctcgt gatttagctg ccttacttgc aattatttta ggtattgcaa
    32221 ctacaatttt gcttactatc atgaataaga tagaaaaagg tggaaattat atttctatct
    32281 ctaagactaa agcgcctctt aaaaaacaaa aaattgcgtc taagccttgg aatatcattg
    32341 ctcacattgt agcatatgga ttgttcacag ttttcatgct tccactaatt tttatagtat
    32401 tatactcatt tacagatcca gttgcaattc aaacaggtaa cttaacatta tcaaacttta
    32461 ctttagaaaa ttatcgctta ttctttagta atagtgcggc attctctcca ttcttggtca
    32521 gctttattta ttctattatt gctgcgacaa cagcaacaat tctcgcagtt gtatttgctc
    32581 gtgttgtcag aaaacataaa tctcgttttg atttcttatt tgaatatggt gctctacttc
    32641 cttggttatt accaagtacg cttttagcag taagtttatt atttactttt aatcagccac
    32701 aatttcttgt cttgaatcag attttggtag gtagtttggt aattctactt attgcatata
    32761 tagttgtaaa aatcccattt tcttatagaa tggtacgtgc tattttattt agtgttgatg
    32821 atgagatgga agatgcagca agaagtatgg gtgcttcacc tttttatact atgatgaagg
    32881 ttatcattcc atttatttta ccggttgttc tctctgttat tgctttaaac tttaactctt
    32941 tattaactga cttcgactta tctgtattcc tttaccatcc cctagctcaa ccattaggta
    33001 ttacgattcg atctgcaggt gatgaaacag caacatctaa tgcacaagct ctggtatttg
    33061 tttatacaat tgttctgatg attatttctg gaacggtatt atacttcaca caaagaccgg
    33121 ggcgtaaagt aaggaaataa tcatgacagc cactagtctt gggttatcaa atattgaaat
    33181 agttgtcagg attgttttat cagtagtcat tggtagtata attggtttag agagagggag
    33241 caaatcccag cctgcaggca tccgaactta tagtattgtt tgtctagctg catgtttgat
    33301 tatgatgacg aatgaatacg tatcttataa atttgggaca ggagatccta cacgattagg
    33361 agctcaagtt atatcaggtg tgggttttct aggcgctgga acgattctta ttacagataa
    33421 aaagaaaatt acaggtctga caactgcagc aggcatttgg gcttcggcag gaattggatt
    33481 agctattgga gtaggttttt atgagggagc tcttttagta gccatttctg tttggggtgt
    33541 gatatccatg ttccaaccac taaaaaaata tctacaaaat cgttctaaaa tgattgaatt
    33601 gtatatagtg gttaaatcta cagaagccta taatcgtgta ttggtttatt gtgcagaaaa
    33661 tggtatcaga atgaccgatt caagaacagc gtttggagat gttaattctg acagaattga
    33721 atactttgat gttccagata aaaaaatagc gtcatttatt actctggaat tatcaggtag
    33781 atttgaacat cttcgactga tggaagaaat tgctaatatt gtaggtgtta tttatgtcga
    33841 agaaattagc tgaaatttag taaacaaagg gacagatgtt tttgtccttt tgttttttag
    33901 atgttttaat catctaattt ttgagtagat ttttgctcag aggtttttat gaaagattat
    33961 aaaatcaatt ttgatttagg taaaatagaa tattttgata ataattgttt gatacaagta
    34021 tacaaattta tttcttttta tgatatttgt gaaatggtgt ttgcctttca tttacctcct
    34081 gatgagttga taacaaatgt tatctttaaa gaaaaaatta actctatgtt aaaatgttac
    34141 attgacaggc tattatatgt ttttataaat cctacacatt ttactgaaaa agttaatcta
    34201 caattttatg gcagtttttt ctcatatgaa tttatttgtc gtgaagttgg aaacattctt
    34261 aaaaataaag gtgtgaaatg caatttaaat ttttttgaag gggaagaata tttgtaaaat
    34321 taattttgtg aatttgtgga tcttaaataa tttactaaat tctcttgtta aaaaaaatta
    34381 aatattgtat agtaatatta gaatgttcgt aatggaggac tgaaatgaaa aatataaatg
    34441 ggaaaaaggt aactatttat gatattgcac gtttatcagg tttttctcca aaaacagttt
    34501 cacgagttat taatggtgga gtaaatgtta aagaagaaac ttatcaagcg attcaaaaag
    34561 ttatagagga attgtcgtat attccaaatg cgtatgcaaa aaatttaact aaaaaagaag
    34621 ctataaatat attgatttct gtaaaaaaaa tcgactcttt tcctttaatt tggtttcata
    34681 cgctgttaga taaagtgtta cggacgtgta aagaatttgg tgttaatgct atagttgagt
    34741 actttggaga ggaggataca attagtaatt caattatatc aagcacaggt agcctagtag
    34801 atggtgttat tgttttttat gaaagtgtag atgatatcag aattcagtat ttaaagaaga
    34861 accatatgcc ttttcttgtt ttcggtgaat ctcaaacgtc tggagtagtc tatgtatcta
    34921 ataataattt tcaagctact tatgatatga tgaaagctgt aactgaagaa aaatttaaaa
    34981 atatgtggtt gcttatggga ggagaatccc atgttaataa ggatcgtgaa agaggtgtgc
    35041 gttcttttct gaatgataaa aattacttta tggatttaaa agtcatttat ggcttatcta
    35101 caattgattc agtttattct tatgcaatgc agcacttgac tacccaaaat tatccggaca
    35161 ttatttttgt ttcaggagat gaaaaggttc agggcttgat tcgtgcgtgc tatgagaaag
    35221 gaattcttat tccagatgat atttctatca ttggatttga taatattcct atttctcagt
    35281 attatactcc agctttgtct acaattgctc ccaattatgt taaattggct aaagaaatga
    35341 tagaaggtgt tttagcaatt attaaagggg aaagtgtcac atctgttgaa gtttctccta
    35401 aatttgttag gagacagagt ttctagtatt gtttaattct tgaaaatcct agtggaaaag
    35461 atggagtgtt ctaaaataag ttctgtttag cctccattca gtttctattg agttggatcc
    35521 aatttctaac aagtgggaca tgttcatgtt cgatctaagg aagacatggt cacattcgaa
    35581 tgatattttc aaaaaaatcg taaaaaagtc ttgacaaaga aaaaacaaag tattaaaata
    35641 agttcaacaa atcagaaaag taactatttt tgatcttcag ggagcctgtg gtggttgtga
    35701 ataggtggtt ggaagtagtg aaagtgggct gattttgaaa atgaatttga aacaatgaaa
    35761 attcggtgcg cacaccttac agtgcagctt gttgttaaac aaggcagaga tgtaaaggga
    35821 tagtcccttt ataattgagg tggcaccgcg ttaccaacgc cctcacacgg aagtatattc
    35881 tgtgtgtggg cttttttcta tccgtcgttt ggtttatctt ttattagggc cttaagtcgc
    35941 tttgatgaac ttgagttcta tctacagctc cttgcctact actaaaagca aacaaaaagg
    36001 ctggactaat acgaaaaaag ctagtaatac tcaatgaaaa tcaaagagca aactaggaaa
    36061 ctagccgcag gctgctcaaa a
//
LOCUS       DBEJNA010000023        35843 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEJNA010000023 DBEJNA010000000
VERSION     DBEJNA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.23"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(201..2459)
                     /locus_tag="ACL3JB_001238"
     CDS             complement(201..2459)
                     /locus_tag="ACL3JB_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0685967.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGFA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2688..2918)
                     /locus_tag="ACL3JB_001239"
     CDS             complement(2688..2918)
                     /locus_tag="ACL3JB_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0685968.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3108..3791
                     /locus_tag="ACL3JB_001240"
     CDS             3108..3791
                     /locus_tag="ACL3JB_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0685969.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3791..4525
                     /locus_tag="ACL3JB_001241"
     CDS             3791..4525
                     /locus_tag="ACL3JB_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0685970.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4679..5536
                     /locus_tag="ACL3JB_001242"
     CDS             4679..5536
                     /locus_tag="ACL3JB_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0685971.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5678..6550
                     /locus_tag="ACL3JB_001243"
     CDS             5678..6550
                     /locus_tag="ACL3JB_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0685972.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3JB_001244"
     CDS             6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3JB_001244"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0685973.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7529..8740
                     /locus_tag="ACL3JB_001245"
     CDS             7529..8740
                     /locus_tag="ACL3JB_001245"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0685974.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8742..9302
                     /locus_tag="ACL3JB_001246"
     CDS             8742..9302
                     /locus_tag="ACL3JB_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGR0685975.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKNNKGDTQ"
     gene            9299..10108
                     /locus_tag="ACL3JB_001247"
     CDS             9299..10108
                     /locus_tag="ACL3JB_001247"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0685976.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10605..10742
                     /locus_tag="ACL3JB_001248"
     CDS             10605..10742
                     /locus_tag="ACL3JB_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0685977.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     T"
     gene            10815..11564
                     /locus_tag="ACL3JB_001249"
     CDS             10815..11564
                     /locus_tag="ACL3JB_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0685978.1"
                     /translation="MTGHSLGCYLAQIAAVEAYQKYPDFYNHVLRKVTTFSAPKVITS
                     RTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTPLIHNDRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11589..12101
                     /locus_tag="ACL3JB_001250"
     CDS             11589..12101
                     /locus_tag="ACL3JB_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGR0685979.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12759..13469
                     /gene="deoD"
                     /locus_tag="ACL3JB_001251"
     CDS             12759..13469
                     /gene="deoD"
                     /locus_tag="ACL3JB_001251"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0685980.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13492..14016)
                     /locus_tag="ACL3JB_001252"
     CDS             complement(13492..14016)
                     /locus_tag="ACL3JB_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR0685981.1"
                     /translation="MKTAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14069..14305)
                     /gene="rpsT"
                     /locus_tag="ACL3JB_001253"
     CDS             complement(14069..14305)
                     /gene="rpsT"
                     /locus_tag="ACL3JB_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0685982.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14373..15293)
                     /gene="coaA"
                     /locus_tag="ACL3JB_001254"
     CDS             complement(14373..15293)
                     /gene="coaA"
                     /locus_tag="ACL3JB_001254"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0685983.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15483..15886
                     /locus_tag="ACL3JB_001255"
                     /pseudo
     CDS             15483..15886
                     /locus_tag="ACL3JB_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16093..16683
                     /locus_tag="ACL3JB_001256"
     CDS             16093..16683
                     /locus_tag="ACL3JB_001256"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0685984.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16680..17957
                     /locus_tag="ACL3JB_001257"
     CDS             16680..17957
                     /locus_tag="ACL3JB_001257"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0685985.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17975..18637
                     /gene="deoC"
                     /locus_tag="ACL3JB_001258"
     CDS             17975..18637
                     /gene="deoC"
                     /locus_tag="ACL3JB_001258"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0685986.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18624..19013
                     /locus_tag="ACL3JB_001259"
     CDS             18624..19013
                     /locus_tag="ACL3JB_001259"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0685987.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19103..20155
                     /locus_tag="ACL3JB_001260"
     CDS             19103..20155
                     /locus_tag="ACL3JB_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0685988.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20299..21834
                     /locus_tag="ACL3JB_001261"
     CDS             20299..21834
                     /locus_tag="ACL3JB_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0685989.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21827..22885
                     /locus_tag="ACL3JB_001262"
     CDS             21827..22885
                     /locus_tag="ACL3JB_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685990.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22888..23844
                     /locus_tag="ACL3JB_001263"
     CDS             22888..23844
                     /locus_tag="ACL3JB_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0685991.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            complement(23880..24521)
                     /gene="plsY"
                     /locus_tag="ACL3JB_001264"
     CDS             complement(23880..24521)
                     /gene="plsY"
                     /locus_tag="ACL3JB_001264"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0685992.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            24657..26600
                     /gene="parE"
                     /locus_tag="ACL3JB_001265"
     CDS             24657..26600
                     /gene="parE"
                     /locus_tag="ACL3JB_001265"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0685993.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSNWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            26615..26819
                     /locus_tag="ACL3JB_001266"
                     /pseudo
     CDS             26615..26819
                     /locus_tag="ACL3JB_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            27020..29491
                     /gene="parC"
                     /locus_tag="ACL3JB_001267"
     CDS             27020..29491
                     /gene="parC"
                     /locus_tag="ACL3JB_001267"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0685994.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELCEKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEYK"
     gene            29623..30645
                     /locus_tag="ACL3JB_001268"
     CDS             29623..30645
                     /locus_tag="ACL3JB_001268"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0685995.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            30701..31405
                     /locus_tag="ACL3JB_001269"
     CDS             30701..31405
                     /locus_tag="ACL3JB_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0685996.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            31470..32159
                     /locus_tag="ACL3JB_001270"
     CDS             31470..32159
                     /locus_tag="ACL3JB_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0685997.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            32156..33079
                     /locus_tag="ACL3JB_001271"
     CDS             32156..33079
                     /locus_tag="ACL3JB_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0685998.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            33094..33738
                     /gene="pcp"
                     /locus_tag="ACL3JB_001272"
     CDS             33094..33738
                     /gene="pcp"
                     /locus_tag="ACL3JB_001272"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0685999.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            33906..34136
                     /locus_tag="ACL3JB_001273"
     CDS             33906..34136
                     /locus_tag="ACL3JB_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0686000.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            34186..34266
                     /locus_tag="ACL3JB_001274"
     tRNA            34186..34266
                     /locus_tag="ACL3JB_001274"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34220..34222,aa:Tyr,seq:gta)
     gene            34276..34347
                     /locus_tag="ACL3JB_001275"
     tRNA            34276..34347
                     /locus_tag="ACL3JB_001275"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34308..34310,aa:Gln,seq:ttg)
     gene            34509..35711
                     /gene="rpsA"
                     /locus_tag="ACL3JB_001276"
     CDS             34509..35711
                     /gene="rpsA"
                     /locus_tag="ACL3JB_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0686001.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        10620 a         6426 c         8171 g        10626 t
ORIGIN      
        1 cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
       61 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
      121 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
      181 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
      241 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt
      301 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
      361 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg
      421 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
      481 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
      541 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
      601 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
      661 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
      721 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
      781 tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc
      841 tcatcatagc caacataacc tggaggggcg ccgaccaact tagccacact atgtttttcc
      901 atgtattcac tcatatcaaa gcgaatcata ctatcagcaa aaccaaaaag ttcgatagcc
      961 agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg
     1021 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     1081 tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag atggatgagt
     1141 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     1201 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     1261 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     1321 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     1381 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     1441 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     1501 gcagcatctg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     1561 atagtgattg tttcgtccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     1621 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     1681 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     1741 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     1801 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     1861 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     1921 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     1981 ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg
     2041 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     2101 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     2161 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     2221 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     2281 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     2341 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     2401 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     2461 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     2521 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     2581 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     2641 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     2701 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     2761 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     2821 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     2881 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     2941 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct
     3001 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     3061 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     3121 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     3181 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa
     3241 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     3301 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     3361 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     3421 atagtggtgc ttatgtttcg gagattgttc gtgccggaat caatgcggtt ccaaaaggtc
     3481 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     3541 tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     3601 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     3661 tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga
     3721 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     3781 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     3841 gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat
     3901 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     3961 aaccaagggg aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt
     4021 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     4081 tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca gggaagttgc
     4141 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     4201 tccacagagt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg ggttggctat
     4261 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg agatggttgg
     4321 agaagttctg gctgttatgc aagatctagc caagtcagga atgaccatgg ttatcgtaac
     4381 acatgagatg ggatttgccc gtgaggtggc agatcgtgtc atctttatgg cagacggtgt
     4441 ggttgttgaa gacggaacac cagaacagat ttttgaacaa acccaagaac aacggactaa
     4501 agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     4561 gttcaatcag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     4621 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     4681 gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa
     4741 gactgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga ttttggttgg
     4801 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     4861 ctcccgtagc gaagtagtgc gagttccaga gactattact caagaggaat tgttagacct
     4921 gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc
     4981 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     5041 tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac
     5101 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     5161 ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
     5221 aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg tggctgctaa
     5281 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
     5341 accaggtgcg gttgtcattg acgttgggat gaatcgagat gaaaatggga agctctgtgg
     5401 agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag tccctggagg
     5461 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
     5521 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
     5581 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
     5641 cctttttgtt gtataataaa agtgagaggg aaaaaggatg aaagtgatta atcaaacctt
     5701 actagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
     5761 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5821 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5881 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     5941 gcaattggag aaggcagaag ttatcttgct ggggcctggt ttaggagacg atgcttctgg
     6001 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6061 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6121 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6181 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6241 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6301 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6361 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6421 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6481 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gatagggtaa gcaaagataa
     6541 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6601 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
     6661 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt tgtaaaaata
     6721 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6781 aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat
     6841 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6901 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     6961 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7021 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7081 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7141 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7201 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7261 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7321 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt tattgaaaat
     7381 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7441 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7501 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7561 attggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7621 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc
     7681 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7741 agctgaaagc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7801 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7861 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     7921 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     7981 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8041 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8101 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8161 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8221 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8281 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8341 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8401 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8461 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8521 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8581 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8641 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
     8701 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8761 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag
     8821 aattgacaaa cttgggactg gaaaaggttg agagctacat caatagtggc aatattttct
     8881 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     8941 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9001 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9061 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9121 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9181 agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9241 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa taataaagga gacacacaat
     9301 gacattttta aacaaaatcc atgaaactgc tactttcctg aaagaaaagg gaattgcagc
     9361 ccctgagttc ggtctaatcc ttggatcagg acttggagaa ttggcagaag aaatcgaaaa
     9421 tccagttgta gtagactatg ctgagattcc aaactggggc cgttcaacag tagtcggtca
     9481 tgctggtaaa ttggtatatg gtgaactggc aggtcgcaag gtcttggctc ttcaagggcg
     9541 tttccatttc tatgaaggga atcctctgga agtggtgact ttcccagttc gtgtgatgaa
     9601 agttcttgga tgtgaaggtg ttattgtaac caatgcagct ggcggtatcg gatttggtcc
     9661 tggtaccttg atggctatct cagaccatat caacatgacg gggcaaaatc cattgatggg
     9721 tgaaaacttg gatgactttg gcccacgttt cccagatatg tctagggcct acacaccaga
     9781 ataccgtgcc actgcccatg aagtggctaa aaaacttaat atcaagcttg atgaaggtgt
     9841 ctatatcgga gttactggtc cgacttatga aacaccagca gaaattcgtt cctataagac
     9901 actgggagca gatgcagttg gcatgtctac ggttcctgaa gttatcgtgg cagcccactc
     9961 tggcttgaaa gttctgggaa tttcatgtat cactaacttt gcggccggtt tccaagaaga
    10021 actcaatcac gaagaagttg tagaagtgac tgaacgtgtt aaaggtgatt tcaaaggctt
    10081 gcttaaagcg attcttgctg aattgtaaga aaaaagattt aaaaggggga gtgcctctgt
    10141 tttttcagga ttgactgcct atccggatta aagaagaaac agaggaatac tatgagcttc
    10201 ttcctgctct tataactgaa agaagcggaa gaataggtat gtctgatctg atagccagca
    10261 ttgtgaaaga caagattcta gaatactagc attagcttcc tagccaagca gactagtatg
    10321 ataaggagag atgagaatga attgactttc tgaatttctc agtcttatca tatatagcac
    10381 aatgagattt cgcttgagtc tgcttgtaaa taaacgaaaa gaaagataag aaataatgaa
    10441 aattggtcaa cgaattatgc gctttggcat aaaaaattaa gtatcggagt tgtatctgtt
    10501 gtagtcggct ttgatttcta gctccagctg gaatttcagc caatgaagta aagcaagatg
    10561 taacatctga agtggtaata ggtgtgctag attctaagga ggaattgaaa gagtcagaaa
    10621 atgatgctcc aaaactagaa actcctctta gagaggagcc aagactagct cctcaaacgc
    10681 ttccggaagc aagtgaagtt cttgaaaaca aaagggaaga gtcaaaagta gagataacat
    10741 aaccagctca agcggatgat atccgcaagg ttgttgggga attagccaag gatataagta
    10801 ttactaagtt gtatatgaca ggtcattctc ttggatgtta cctagctcag attgcagcgg
    10861 ttgaagctta ccaaaaatat cctgattttt ataaccatgt attgaggaaa gtgacaactt
    10921 tcagtgctcc taaagtgatt acttccagaa ctgtttggaa tgctaagaat ggtttctggg
    10981 atgttggttt ggaaagtcgt aaattagctg ttagtggaaa aattaagcat tatgtggttg
    11041 ataatgacaa tgttgtgact cccttgattc ataatgatcg tgatattgtt acatttacag
    11101 gtaattcacg ctttaaacac cgttctcgtg gctattttga aagtccaatg aatgatattc
    11161 ctaactttaa tattggtaaa caagctacct tggataaaca tggttatcgt gatccgaaat
    11221 tggataaagt gcgattcttt aagaaacagg ctctgcctcg atcttctagt caaccaagcg
    11281 ctgaaccaat ggaaaatatt gccttaggaa aacaggttac tcaaagttcg acagctttcg
    11341 gaggagatgc tagaagagct gtggatggca aagtcgatgg taactatggt cacaattctg
    11401 tcactcatac aaacttccaa tctaagcctt ggtggcaagt agatttggct aaagaagaaa
    11461 ccattcgcca aatcaatatt tacaaccgaa cagacactgc ccaggataga ttggcaaact
    11521 ttgatgtcat tcttttagac agttctggta aagaaattga gtgaaaacgt ataacatctc
    11581 ctaaagatgt gtcagcacaa attacgatta accataaaaa agcgcgctat gttcggattg
    11641 agctagaagg ctataatgcc ctcagtcttg cagaagttga agttttccgc tttatagcta
    11701 cgaatgctga aacggcgata caagtttcta agtcagttca accaatcagt cagactcctg
    11761 tgaaggataa aacattgaca attcaacaca gtggagctta cattgcccgc tactccataa
    11821 cttgggaaga agttacagta gataaagatg gaaaccaagt tgttcgtagt cattcttggg
    11881 aaggaaacgg tcgcaaccag actgcaggtt ttgtcctcaa cctcccaatc aaagaaaata
    11941 tgagaaatct gcgagttaag attgagaaaa agacgggcct actatggaat agatggcaaa
    12001 caatctatga aaacagacca attttagctc aaccccaccg taaaattacc cattggggta
    12061 cgacattgaa ttccaaggtg agtgacgatg atgtcttgta atctgatggt acaatgacag
    12121 ttagtttgtc tagtttataa gaaagtacta cctgagcttg aataggactc aggtagctct
    12181 ctgtgaaaga acaaaattaa tactcaatga aaatcaaaga gcaaactagg aaactagccg
    12241 caggttgctc aaagcactgc tttgaggttg tagataagac tgacgaagtc agtcacatat
    12301 ataatccaag gcgacgttga cgtggtttga agagattttc gaagagtata aacagaaagg
    12361 tagagcgcgt gttctaattt gaacacgagt agaaaacttt tctaaaaata aaaacgaaag
    12421 gatgggtaaa ctgtattcgc tgaactgaat acgggcgact ctcctctaaa tcaaaattaa
    12481 gaaagaaagg aattgacccc accctaaaag cagtgggaaa aagatagttg gtctagcgag
    12541 catcgctcac tgcgcccaac tcctattttc ccttcgcttt ttgatgggtt tggtatcttt
    12601 ctcaatataa aatataaaat aaagaaaggt agagcgtgtg ttttgatttg aacacgagcg
    12661 gaaaactcgg aaaatagata atctgactga aaaatcagga tttctcgtca ggttcctaat
    12721 tttcagtcgt tttcttctcg ctctttgtat cataaattat gtctatccat attgctgctc
    12781 agcagggtga aattgctgat aaaattcttc ttcctgggga tcctcttcgt gctaagttta
    12841 ttgcggagaa tttccttggt gatgctgttt gttttaacga agtgcgtaac atgtttggtt
    12901 acactggtac ttacaagggt caccgtgtat ctgtcatggg aactgggatg ggaatgccat
    12961 ctatttcgat ttatgcgcgt gagttaatcg tagactacgg tgtgaagaaa ttgattcgtg
    13021 tgggaactgc aggttctttg aatgaagagg ttcatgttcg tgaattagtt ttggcgcagg
    13081 cggctgcaac caactcaaac atcgttcgta atgactggcc acagtacgat tttccacaaa
    13141 ttgctagctt tgatttgctt gataaagcct accatatcgc caaagaactt ggtatgacta
    13201 ctcacgttgg gaacgttttg tcatctgatg tcttttactc aaattacttt gaaaagaata
    13261 tcgagcttgg taaatgggga gtcaaggctg tggaaatgga agcagcagct ctttactatc
    13321 ttgctgccca ataccatgtt gatgcgctag ctatcatgac catctctgat agcttggtca
    13381 atccagacga agacacaact gcagaagaac gtcaaaatac cttcactgat atgatgaagg
    13441 ttggtttgga aaccttgatt gcagaataat tatagccaaa aaggaagccc tttatgaatt
    13501 gtaggacttc cttttcttat ccagaaattg atctagctct ctctgatttc gaagaatagt
    13561 gactttatgt gaatattctt ggcaaagttt ttggtaattt tctttttgag ttttgctacg
    13621 tccatcccaa agaatccatc tgataaactc ccagtcaaag cgttcagggc aatctgccgc
    13681 catactttct ctgacttttc cacggtattt aagataacgc ttaaaggctc taaagagaca
    13741 ggtcaatggc gaaaaattga gaaagatgat ttggtcagct tcttgcattc gttcttggta
    13801 gtagcaccaa gaataattac catcgatgac ccaagcttta tgcttggtga gaaagttttt
    13861 tatctcggtt aacatccatt cgtggtcact gtcttgccaa ccaggttgaa attggagtgt
    13921 gtccatgtgc agttttggaa tggagtagta gttagataac ttttctgcta gagttgactt
    13981 accagaacca gaatatccga taattgcggt tttcattttc taccttttcc tatttggaga
    14041 caaaaaaaca gcctctatgg actgtttctt atttagcaag tttagctgaa agacgagctt
    14101 tatcgcggct tgctttgttt ttgtgaatca aacctttagt ttctgcttta tcgatagctg
    14161 agctagcagc acggaaaagt tcttcagatg ggtttgcttc gaaagctttt atagcagtac
    14221 gcatagctga tttttgagct gagttctttt cgttttgttt aacgttcaat tcagcgcgtt
    14281 tgatagctga tttaatgttt gccaatgttc ttacctccat atttactaac tataccatta
    14341 tatatgaaaa cttacgtttt gacaagggaa aattactttt ttaagtaaat ttcatcgatt
    14401 tcatggttct tgcttttatg aagaatcact tctgcacgat ttctggttgg ttcaatataa
    14461 ttttgcagat ttgtgagatt gatactgatc cagacctgat gggcaaagga ctccacttcc
    14521 ccaatcggca tctgagtaaa acgataatag tagctatcag ggtcgttttg ggctaggctc
    14581 agcattttca agaaacggtc cagataccaa ctttcaatat catccactcc agcatctaca
    14641 tagatggaaa agtcaaagaa gtcagtgata tagagacgat cgttttgtgg attttgaaag
    14701 acattaattc cctcaacaat tacaaaatca gcagctttga cactttgttt ctcttcgggt
    14761 acgatgtcgt aaacttcatg agaatagaca ggaatatcta catcttgtcc atttttgatg
    14821 cggtccaaga agttgagaag agcttccata tcatagcttt caggaaatcc tttacgattt
    14881 aaaatcccct gctcaatcaa ggtttgattg ggatagagaa aaccatcagt tgtaaccaac
    14941 tcaaccgtag catctgtaaa cgtacgggac agtaggattt gaagtaggcg actggttgtg
    15001 gattttccaa cggcaacact cccagaaacc ccaataataa aaggttgaga tttactttca
    15061 cgttggagga aaattccttt tgaaaaggct aaatcttcct tagttcgctt gtaaatctga
    15121 atcagatgag ccaaggggag atagatatct gtaacgtctt ggagactgat ttggtcatta
    15181 aaactcttga tagattccaa ttcttcttct gtcaaaggag gtgttgtctt tcgatgtaaa
    15241 gattgccaag tctggcggct gattttttca aaatgtaaaa attcgttggt catttgtttt
    15301 cccctaggta ttttgtctat cataccataa aaagctaaaa aaataaagcg gtttctcgaa
    15361 tgtggtaagt caatggtata tagtataagt gatcaattta ttgatgaaat aggagataga
    15421 ttctactgat ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta
    15481 ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac
    15541 cttttataaa aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt
    15601 ttactttttt gatggaacat gctattgtaa cagctgtctt tatctgttcg ttcttaattg
    15661 ctttcttact aaaaaacgat gggcgaaatg gattgctgcg ggtagttatt gctttttagt
    15721 cctatggatt gcgacagagg gttatttctt ccacatgtca ctagaagatt tgatacgact
    15781 ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc taaacatttt
    15841 gttgggaatt ttgttgataa taaagaattt taaggttaag caatagaaat aataatctgc
    15901 ctgattatag atgataaact ttttgttttt atctggactg tgatatttat agttctaaat
    15961 ggtttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga ctcgctttct
    16021 tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt caaattatgg
    16081 taaaatagtg tcatgagtaa aatgtattat gcagaaaatc ctgacgctgc tcacgacatt
    16141 catgagttga gagtggactt gttgggacaa aaaatgactt ttttgacaga tgcgggtgtt
    16201 tttagcaaga aaatggttga ctttggaagt caactcttgc tcaagtgtct ggatgtcaac
    16261 caaggagaga cagtcctaga tgtaggctgt ggttatggtc cattaggttt gtccttggtc
    16321 aaggtttacg gagttcaggc gaccatggtt gatattaaca ctcgtgccct ggatttagct
    16381 cagagaaatg ctgaaaaaaa taatgcaaaa gcgacgatat ttcaatctaa tatttatgca
    16441 agagttcaag ggcgatttga ccatgtcatt tccaatcctc ctatccgtgc gggcaagcaa
    16501 gtcgttcatg aaatcatcga gaaaagtaaa gatttcttgg aaactggtgg ggatttgaca
    16561 atcgtcatcc agaaaaaaca aggggctcca agtgctaagt ccaagatgga ggatgtgttt
    16621 ggtaattgtg aaatccttaa aaaagacaaa ggatactata tccttagaag tgtgaaagaa
    16681 tgagagcagt tgatttaatc caaaaaaaac gagacggtca agaactgact tcaagtgaaa
    16741 ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc tgattatcag atgtctgcct
    16801 ttgctatggc tgtttatttt aaaggaatga cgactcgaga aatctctgat ttaacgatga
    16861 atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg aaagttgaca
    16921 agcattctac tggtggtgtc ggcgataagg taaccttgat tttagctcct cttgttgcta
    16981 gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca ggcggaacaa
    17041 ttgataaatt ggagtccatt aagggctatc aagtagaacg tagtcaagag gattttattc
    17101 gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg gtcaaagcag
    17161 ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt cctttgattg
    17221 cgagttcggt gatgagcaag aaaattgcgg caggggcgga tgctattttg ctagacgtga
    17281 ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg gctcaaacta
    17341 tggtagatct tggtaaggtt gttggacgga agacagtagc agtgattacg gatatgagcc
    17401 agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg gagattttgc
    17461 aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa attatgcttg
    17521 gtttggcaaa tgttaacaaa actgttgaag aagttcgcca acatcttgaa aatggtcaag
    17581 cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa gacctctatc
    17641 gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt gtcatttcag
    17701 ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt cgtgcagtta
    17761 agtctgatgt cttggactat gaaacaggaa ttgtttttga aaagaagatt ggagactccg
    17821 ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca cctcaactag
    17881 ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc cgtgaaattg
    17941 tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat atatagatca
    18001 tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt ctgaggctag
    18061 agagtatgac tttgccagtg tttgcgttaa tccgacctgg gttgaacatg ctaaaaaagg
    18121 acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccctttgg gagcaacaac
    18181 ttcagccgtg aaagcatttg agacaaaaga agctatccaa aatggtgcag atgagattga
    18241 tatggtgatc aatgttgggg ctctcaagtc aggtgatttg gccttggttg agtcagatat
    18301 tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa gtcattattg aagcttgcct
    18361 tctgacagac caagaaaaag ttgttgtttg ccaattggcc caaaaagctg gggctgactt
    18421 tgtcaaaaca tctactggct tttcaactgg tggtgctacg atagcagatg ttacattaat
    18481 gcgtgaaaca gttggatctg atatgggtgt caaggccgcc ggtggagctc gttcttatgc
    18541 agatgctctt gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag ctggggtagc
    18601 tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg gcaattgaaa
    18661 ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt ttagtagcta
    18721 aagacggaag tgtttacacg ggagtgaata tcgaaaatgc tagctatcct ttgaccaatt
    18781 gcggtgagag aacagcagtt tttaaggcta tatctgaagg ccaaagagaa ttttcagaat
    18841 tgattgtcta tggtcaaact gaaaaaccga tctcgccatg tggtgcttgt cgccaagtga
    18901 tggctgaatt ttttgaacaa gatctaaaag tgaccttagt cgcaaaagat aaatcgacgg
    18961 tcgagatgac ggtcggggaa ttacttccat actcttttac agacttaaac tagtctgagt
    19021 cgctctctga gtggcacggt ccttgtggcc aaccaatcca tacttgcaac atcgttgcac
    19081 atcttattta ggaggttcag taatgaacaa gaaacaatgg ctaggtcttg gcctagttgc
    19141 agtggcagca gttggacttg ctgcatgtgg taaccgctct tctcgtaacg cagcttcatc
    19201 ttctgatgtg aagacaaaag cagcaatcgt cactgatact ggtggtgttg atgacaaatc
    19261 attcaaccaa tcagcttggg aaggtttgca ggcttggggt aaagaacaca atctttcaaa
    19321 agataacggt ttcacttact tccaatcaac aagtgaagct gactacgcta acaacttgca
    19381 acaagcggct ggaagttaca acctaatctt cggtgttggt tttgcccttc acaatgcagt
    19441 tgaagaagca gctaaagaac acactgactt gaactatgtc ttgattgatg atgtgattaa
    19501 agaccaaaag aatgttgcga gcgtaacttt cgctgataat gagtcaggtt accttgcagg
    19561 tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg gtatcgaatc
    19621 tgaagttatc tctcgttttg aagcaggatt caaggctggt gttgcgtcag tagacccatc
    19681 tatcaaagtc caagttgact acgctggttc atttggtgat gcggctaaag gtaaaacaat
    19741 tgcagccgca caatacgcag ccggtgcaga tattgtttac caagtagctg gtggtacagg
    19801 tgcaggtgtc tttgcagagg caaaatctct caacgaaagc cgtcctgaaa atgaaaaagt
    19861 ttgggttatc ggtgttgacc gtgaccaaga agcagaaggt aaatacactt ctaaagatgg
    19921 caaagaatca aactttgttc ttgtatctac tttgaaacaa gttggtacaa ctgtaaaaga
    19981 tattgctaac aaggcagaaa aaggagaatt ccctggcggt caagtgatcg tttactcatt
    20041 gaaggataaa ggggttgact tggcagtaac aaacctttca gaagaaggta aaaaagctgt
    20101 cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa aataatggat
    20161 ggaagtcatt tcttaggaag cggccaaggg ccgctttttt aagagttgag acaaagtcat
    20221 tttgtctcag taaagcttgc tactagacaa actagcaagt tttattgaaa taaaataaga
    20281 ctctgaaagg aagagcacat ggcacacgaa aatgtcattg agatgcgtga tattaccaag
    20341 gtgtttggtg gatttgttgc caacgacaaa atcaacttgc acctacgaaa aggtgaaatt
    20401 catgcacttt taggagaaaa tggggctggt aagtccacgc taatgaacat gttagcaggc
    20461 cttcttgaac caactagtgg tgaaatcgcg gtcaacggtc aagttgtcaa tctcgactcc
    20521 ccatctaaag cagctagctt gggaatcggg atggttcacc agcactttat gttggttgaa
    20581 gccttcacag tggctgaaaa catcatttta ggtagtgaat tgactaaaaa tggtgtgcta
    20641 gatatcgctg gagctagcaa agaaatcaag gctctttctg aacgttatgg cttagctgtt
    20701 gacccttctg ccaaggtagc agatatctca gttggagccc aacaacgtgt agaaatttta
    20761 aaaacacttt atcggggggc tgatatcctt atctttgacg aaccaacggc tgttttgact
    20821 ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga aggaaaatca
    20881 attatcttga ttacccacaa attggatgaa attcgcgcag tttctgaccg tgttacagtt
    20941 atccgtcgtg ggaaatcaat tgaaaccgtt gaaattgcag gggctaccaa tgctgatttg
    21001 gcggaaatga tggtaggacg ttctgtttcc tttaaaacag agaagcaagc ctctaaacca
    21061 aaagaagtgg ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg tgttccagct
    21121 gttaaaaatc tgtccttgga tgttcgtgct ggagagattg ttggtattgc ggggattgat
    21181 ggaaatggtc agtctgaact gattcaagcc attacaggtc ttcgtaaggt tgaatctggt
    21241 agcattgagc taaaaggaga ttcaattgta ggcttgcacc cacgtcagat tacagaacta
    21301 agtgttgggc acgttccaga agaccgtcac cgtgatggct tgattttgga aatgatgata
    21361 tctgaaaata ttgcccttca aacctactat aaagaaccac atagtaaaaa tggaattttg
    21421 aattattcaa atattacttc ttatgctaaa aagctgatgg aagagtttga tgttcgcgct
    21481 gccagtgaat tagttcctgc agctgcactc tcaggaggaa atcaacaaaa agcaattatt
    21541 gctcgtgaaa ttgatcgaga tcctgatctc cttatcgtta gccagccaac tcgtgggttg
    21601 gatgtcggtg ccattgagta tatccacaaa cgcttgattg aagagcgtga taatggcaag
    21661 gctgtccttg ttgtcagctt tgaattggat gagattttaa acgtctcaga ccgtattgcc
    21721 gttatccacg atggtaagat tcaaggtatt gtatcaccag aaacaaccaa taaacaagaa
    21781 cttggtgtct tgatggctgg tggaaacttg ggaaaggaga agagtgatgt ctaaaaaatt
    21841 acaacaaatt tcggttccct tgatttctgt atttctagga attttactcg gagccattgt
    21901 catgtggatc ttcggttatg atgctatttg gggctacgaa gaattgttct atacagcctt
    21961 tggcagtctg cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg tcttgattgg
    22021 tcttggtttt gcggttgcca gtcgagctgg tttctttaac gtcggacttc ctggtcaggc
    22081 tttggcaggt tggattctca gtggttggtt tgcgctgtcg catccagata tgccccgtcc
    22141 cttgatgatt ctagcaacca tcgtgattgc cttgattgct ggtgggattg tcggagcgat
    22201 tccaggtatt cttagggcct atctagggac gtcagaggtt attgtaacca tcatgatgaa
    22261 ctacattgtc ttgtatgtag gaaatgcctt tatccatgct ttccctaaag acttcatgca
    22321 aagtacagat tcgaccattc gtgttggggc taatgcaacc tatcagacac cttggttggc
    22381 tgagttgact ggtaactcac ggatgaatat tggtattttc tttgccatca ttgccgttgc
    22441 agttatttgg ttcatgctca agaaaacaac tcttggtttt gaaatccgtg cagttggtct
    22501 taatccacat gcttcagaat atgctggtat ttctgccaag cggactatta tcctatctat
    22561 gattatttca ggtgccttgg caggtcttgg tggagctgtt gaaggtttgg gaaccttcca
    22621 gaacgtctat gttcaaggtt cgtcattagc tatcggattt aacggaatgg cggttagttt
    22681 gcttgcggcc aactcaccaa ttggtatact ctttgcagcc ttcctatttg gcgttctcca
    22741 agttggggct cctggtatga atgcggcgca ggtaccatct gagcttgtca gcattgtaac
    22801 agcgtctatt atcttctttg tcagtgttca ttaccttatc gaacgctttg tcaaaccgaa
    22861 aaaacaagtt aaaggaggta agtaaagatg tctattataa ccttgctccc cctcttggtg
    22921 tcttctatgc tgatttactc agcacctctc atctttacaa gtatcggtgg tgttttctct
    22981 gaacgtggtg gtgtggtaaa cgttggcctt gaaggaatta tggttatggg tgccttttct
    23041 ggagttgtct ttaaccttga atttgcagaa caatttggag cagcaactcc atggctatcc
    23101 ttgcttgtag caggattggt tggtagtgtt ttctctatca tccacgcagc agcgacggtt
    23161 catttccgtg cagaccatgt tgtcagcggt acggtattga acttgatggc gcctgccttg
    23221 gctgttttct tagttaaagt tctttataac aaaggacaaa ccgacaacct aagtcaaact
    23281 tttggacgct ttgatttccc agtcttggca aatatcccag tgattggtga tatcttcttc
    23341 aagtcaacta gtctacttgg ttatctggcg attgccttct cattccttgc ttggtttatt
    23401 ctctttaaga ctcaatttgg tcttcgtctc cgctctgtcg gtgaacatcc tcaagcagcg
    23461 gataccttgg gaatcaacgt ctacaagatg agatatttag gggttattat ttcaggtttt
    23521 ctaggtggaa ttggcggagc gatttatgcg caatcaatct cagttaactt ctcagtgaca
    23581 actattgttg gacctggatt tatcgccctt gctgcgatga tctttgggaa atggaatcca
    23641 atcggtgcta tgctttctag tctcttcttt ggactttcac aaagtttggc tgttatcggt
    23701 tctcaattgc cgttcctaca aggagtgcca gcggtttatc ttcaaattgc accttatgtt
    23761 ttgacaattc ttgtcttagc agccttcttt ggaaaagcag tcgcaccaaa agcagatggt
    23821 atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt cagtccaatg actggcgttt
    23881 tattttttag gatcttgatg agttaggttc aatccccaag ggaccaaatt ttcagtttta
    23941 tttttgatac gagctatatt gtccttatga cgaatgataa tcaaactagc aagtgctaag
    24001 ataatagcga tgaagagaga gtcatagtta ctcaggataa aaccaaaaag tggaaagagc
    24061 agaaccccga taacagccgc gatcgatgct gtgacactag acagtgaaat catactgcca
    24121 agatagagag ctccaaagaa gataatcgca aggtagagac agaagatagg cgcaaatccg
    24181 aaaatcactc cagcactggt tgcgacagcc ttaccacctt taaatcctgc aaagataggg
    24241 aaggtatggc cgataacagc caaaagtcca aagatgagag gagaaacgcc ttgtagatga
    24301 aaaataatcg gaagcagcgt tgctagggtt cctttgaaaa agtcaatcac aaaggttgcc
    24361 ataccagctt tcttacctaa aatgcggaag gtattggtcg ttccagtgtt accagaacca
    24421 tgctcgcgta gattgatttg aaagaatact tgtccaatcc agagaccaga tggaatcgaa
    24481 cccagcagat aggctaggat taataaaact attgtaatca tactcctatt atatcatgaa
    24541 ttgggaaaga aaagcagaga atctctgctg aaattgtcac atcggagaaa gaaaaatttt
    24601 gcaaaatcct tggaaaacct gtagaatagt aaagatgaac gaataggagg ttccttgtgt
    24661 caaaaaagga aatcaatatt aacaattata atgatgatgc tattcaggtg ctagaagggt
    24721 tggatgcggt ccgaaaacgt ccagggatgt atattggatc gaccgatggc gctggtcttc
    24781 atcacctagt ttgggaaatc gttgataatg cagtcgatga agccttgtct gggtttggtg
    24841 atcgtattga tgtaactatc aataaagacg gtagtctaac ggttcaagac catggacgtg
    24901 ggatgccgac aggtatgcac gctatgggaa ttccaactgt tgaggttatc tttaccattc
    24961 ttcatgccgg agggaaattc ggtcaaggtg gctataagac atcaggtgga cttcacggag
    25021 tgggttcttc cgttgttaac gccctttcta actggttaga agttgaaatt acccgtgatg
    25081 gtgcagttta caagcaacgt ttcgaaaatg gtggaaaacc tgtcacgact ttgaagaaaa
    25141 tcggtacagc acccaagtct aaaacaggca ccaaagttac ttttatgcct gacgcgacta
    25201 tcttttctac gacagatttc aagtacaata ccatttcaga gcgccttaat gaatcagcct
    25261 ttctcttgaa aaatgtgacc ttgtctttaa cggacaagcg aacagatgaa gcgattgagt
    25321 tccactatga gaatggagta caagattttg tttcttatct caacgaagat aaggaaatct
    25381 tgacgccagt tctttacttt gaaggggaag acaatggttt tcaagtggaa gtagccctcc
    25441 agtacaatga tggattctca gataacattc tatcctttgt caataacgtt cgcaccaagg
    25501 acggtggaac gcacgagaca ggattcaagt ctgccattac caaggtcatg aatgactatg
    25561 cacgtaaaac aggtcttctc aaggaaaaag ataaaaacct tgaaggttca gactatcgtg
    25621 agggactagc ggccgttctt tctatcttag ttcctgaaga acacttgcag tttgaaggac
    25681 agaccaagga taaactagga agccccctag ctcgcccagt tgtggatgga atagtggctg
    25741 ataagttgac ctttttcctt atggaaaatg gggaattagc ttctaacctc atccgcaagg
    25801 ctatcaaggc ccgtgatgct cgtgaagcag cacgtaaggc gcgtgatgag agccgaaatg
    25861 ggaagaaaaa caagaaagat aagggcttgt tgtctgggaa attgaccccg gcccaatcta
    25921 agaatcctgc taagaatgaa ctctatctag ttgaggggga ctctgccggt ggttctgcca
    25981 aacaaggtcg tgaccgcaag ttccaggcta ttctacctct tcgtggtaag gttgtcaata
    26041 cagccaaggc caagatggcg gatatcctca aaaatgaaga gattaatacc atgatttata
    26101 ccattggtgc gggtgttgga gcagacttct ctattgaaga tgccaactat gataagatca
    26161 ttatcatgac cgatgcggat accgacggtg cccatatcca gaccttgctc ttgacatttt
    26221 tctaccgtta catgcgtccg ctagtcgagg caggtcatgt ctatattgcc ctcccacctc
    26281 tttataagat gtccaaaggt aaaggcaaga aagaagaagt ggcctacgct tggacggacg
    26341 gagaactaga agaactccgt aaacagttcg gtaaaggcgc taccctccaa cgatacaaag
    26401 gacttggtga gatgaatgcg gaccagctct gggaaacaac catgaaccca gaaacacgta
    26461 ccctcatccg tgtcacaatt gaagatttag cgcgcgccga acgccgcgtc aatgttctca
    26521 tgggagataa ggtagaacca cgccgtaaat ggattgaaga taatgtcaag tttacgctag
    26581 aagaagcgac agtgttttaa tgaaagaaaa taatatgtta gtaaactgga aattagagtc
    26641 ggatgtgaat gactatgtga aaaagcagtt tgaaaatctt ggtttgaaaa aattgcagga
    26701 ttattaatga agaatctgct atgagtgctt atctcaaaga ggcgcttaag ggagcggcta
    26761 agacacaaac taagactaat tttggaaaac cagattttca tattgaaaaa tacaaacagg
    26821 atagtttggt tacttatcgt aactgaacac gggaggaatt cccgtaaaat atcttttact
    26881 gcataaaaac ctactctaca ttctttgaaa ggagttgaac acgccctaga tactgtgtga
    26941 aaaagataaa ttctcttgtg agtttgctta cttcaagaat tttctatttt cacttggtat
    27001 tttatgggct ttgtatctta tgtctaacat tcaaaacatg tccctggagg acatcatggg
    27061 agagcgcttt ggtcgctact ccaagtacat tattcaagac cgggctttgc cagatattcg
    27121 tgatgggttg aagccggttc agcgccgtat tctttattct atgaataagg atagcaatac
    27181 ttttgacaag agctaccgta agtcggccaa gtcagtcggg aacatcatgg ggaatttcca
    27241 cccacacggg gattcttcta tctatgatgc catggttcgt atgtcacaga actggaaaaa
    27301 tcgtgagatt ctagttgaaa tgcacggtaa taacggttct atggacggag atcctcctgc
    27361 ggctatgcgt tatactgagg cacgtttgtc tgaaattgca ggttaccttc ttcaggatat
    27421 cgagaaaaat acagttcctt ttgcatggaa ctttgacgat acggagaaag aaccaacggt
    27481 cttgccagca gcctttccaa acctcttggt caatggttcg actgggattt cggctggtta
    27541 tgccacagac attcctcccc ataatttagc tgaggtcata gatgctgcag tttacatgat
    27601 tgaccaccca actgcaaaga ttgataaact catggaattc ttgcctggac cagacttccc
    27661 tacaggggct attattcagg gtcgtgatga aatcaagaaa gcttatgaga ctgggaaagg
    27721 gcgcgtggtt gttcgttcca agactgaaat tgaaaagcta aaaggtggta aggaacaaat
    27781 cgttattact gagattcctt atgaaatcaa taaggccaat ctagtcaaga aaatcgatga
    27841 tgttcgtgtt aataacaagg tagctgggat tgctgaggtt cgtgatgagt ctgaccgtga
    27901 tggtcttcgt atcgctatcg aacttaagaa agacgctaat actgagcttg ttctcaacta
    27961 cttatttaag tacaccgacc tacaaatcaa ctacaacttt aatatggtgg cgattgacaa
    28021 tttcacacct cgtcaggttg ggattgttcc aatcctgtct agctacatcg ctcaccgtcg
    28081 agaagtgatt ttggcgcgtt cacgctttga caaagaaaag gctgagaaac gtctccgtat
    28141 cgtcgaaggt ttgattcgtg tgatttcgat tttggatgaa gtcattgctc ttatccgtgc
    28201 ttctgagaat aaggcggacg ccaaggaaaa cctcaaagtt agctatgatt ttacggaaga
    28261 acaggctgag gctatcgtaa ctttgcaact gtaccgtttg accaataccg atgtggttgt
    28321 cttgcaggaa gaagaagcag agctttgtga gaagattgct atgctggcgg ctattatcgg
    28381 tgatgaaagg actatgtaca atctcatgaa gaaagaactt cgtgaggtca agaagaaatt
    28441 tgcaactcct cgtttgagtt ctttagaaga cactgcgaaa gcaattgaga ttgatacagc
    28501 tagtcttatc gctgaggaag atacctacgt cagcgtgacc aaggcaggtt acatcaagcg
    28561 taccagtcca cgttcctttg cggcttccac cttggaagaa attggcaagc gtgatgatga
    28621 ccgtttgatt tttgttcaat ctgccaagac aacccagcac ctcttgatgt tcacaagtct
    28681 tggaaatgtc atctacagac caatccatga gttggcagat attcgttgga aggacatcgg
    28741 agagcatctg agtcaaacca tcacaaactt tgaaacgaat gaagcaatcc tttatgtgga
    28801 agtactggat cagtttgacg atgcgacaac ctactttgca gcgactcgcc ttggtcaaat
    28861 caaacgggta gagcgaaaag aattcactcc atggcggacc tatagatcta agtctgtcaa
    28921 gtatgctaag ctcaaagacg atacagatca gattgtagca gtggctccga ttaaactaga
    28981 tgatgttgtc ttggttagtc aaaatggtta tgccctgcgt ttcaatatcg aagaggttcc
    29041 ggttgtcggt gctaaggcag caggtgtcaa ggctatgaat ttgaaagaag atgatgtcct
    29101 ccaatctggc tttatctgta atacttcgtc cttctacctc ttgacccagc gtggaagctt
    29161 gaaacgtgtt tccattgagg aaattctagc aaccagccgt gccaaacgag gattacaagt
    29221 cttgcgtgag ttgaaaaaca aaccgcatcg tgtcttcttg gcaggagcag ttgcagagca
    29281 aggatttgtt ggcgatttct tcagtacgga agtggatgtg aacgaccaaa ctctgcttgt
    29341 ccaatccaat aaaggaacaa tctatgaaag ccgattgcaa gacttgaact tgtcagaacg
    29401 cactagcaat ggaagcttca tttctgacac gatttcagat gaagaagttt ttgacgctta
    29461 tcttcaggaa gtagttactg aatataaata agtgaaatga agaataagtt ctaagagctg
    29521 gtttttattg gagaaatttt ctgaaaatta caaaatatac ttgctatttt agaaaaatag
    29581 tgtagaatat aagaaatagg tttttagaat aaggagtgga atatgacagt aacgattgat
    29641 tgggaaaacc tcggtttttc ctatatgaaa ttaccttatc gctatcttgc tcatttcaaa
    29701 aatggacaat gggatcaagg agagcttaca gaggatgcaa ctttgcatat ttcagagtct
    29761 tctccaagtc ttcactatgg acaacaagca tttgaaggtt tgaaagctta tcgtactaag
    29821 gatggcagtg ttcaactgtt ccgtcctgat gaaaatgcta aacgcctgca acgtacatgt
    29881 gaccgtctct tgatgccaca agttccgaca gacatgtttg tagaagcttg taaagcagtt
    29941 gtccgtgcga atgaagaata cgtaccacca tacggaacag gtggaacctt atatcttcgc
    30001 cctcttttga ttggtgtcgg agatattatc ggggtaaaac cggcagaaga gtacattttc
    30061 accatctttg ctatgccagt tggaaattac tttaaaggtg gtttggtccc aaccaacttc
    30121 ttgattcagg atgagtacga ccgtgcagca ccaaatggta caggtgcggc taaggttggt
    30181 ggaaactatg ctgcaagtct cttaccagga aaaatggcca agtcacgtca tttctcagat
    30241 gttatctatc tggacccatc aactcataca aagattgaag aagtcggatc agctaacttc
    30301 tttggaatta cagctgataa tgaatttgta acaccattga gtccatctat cttgccatct
    30361 attaccaagt attccttgct ttatttggca gaacatcgct tgggattaac tcctattgag
    30421 ggtgatgttc caattgataa tcttgaccgt tttgtagagg caggtgcctg tggtacagca
    30481 gcggttattt ctccaattgg aggtattcaa catggtgatg atttccatgt attctatagt
    30541 gaaacagaag taggtcctgt gacgcgtaaa ttatataatg aattgacggg tattcagttt
    30601 ggcgatattg aagcgccaga aggttggatt gtaaaagtag attaaaataa accaaaggag
    30661 attttttatg aaatagaaaa agtggctctt aacagcagga gtggtcctga gcacgtcagc
    30721 tattttagtg gcttgtggaa aaactgataa agaagcagat gcaccgacaa cattttctta
    30781 tgtctatgca gtagatccag catcattggg ctacagtata gcgactcgaa catcgacgac
    30841 agacgttatt ggaaatgtta ttgatggttt gatggaaaat gataaatacg gcaatgttgc
    30901 tccttctcaa aaagactatg atttgaatag tacaggatgg gctccaagct atcaagatcc
    30961 agcgtcttac ttgaatatta tggatccaaa atctggttct gccatgaaac accttggtat
    31021 tacgaaagga aaagataagg atgttgtagc taaacctggt ttggataaat ataagaaatt
    31081 gttagaagat gctgtttctg agaccactga cctagagaag agatatgaaa aatatgccaa
    31141 agctcaagct tggtcgacag atagttcatt attgatgcca acagcttcat ctggtggttc
    31201 tccagttgta agtaacgtag taccattctc aaaaccatac tcacaagttg gtattaaggg
    31261 ggatccatat atctttaaag gaatgaaatt gcaaaaagat attgttacaa caaaagaata
    31321 taacgaggtt tttaaaaaat ggcaaaaaga aaaattggaa tccaatagca aataccaaaa
    31381 agaactagaa aaacacatta aataaggaat ggtattgatc ttgataaaat tttaaaaata
    31441 ctgtcatttt gaatataaag gagtttgata tggagtggat tagattaata ggaatagcaa
    31501 tcattgttgt gggttttatt ttaaaatttg atacaattgc aacagtagtc ttagctggtt
    31561 tggttacagc tttagtttca ggtgtttctc tcgttgaatt tttggagatt ttgggaaaag
    31621 aatttagcaa tcagcgagtg ctcacgattt ttatggttac cttgcctctt gtggggctgt
    31681 cagaaacctt tggactcaag caacgatcaa tcgatttgat tcgaaagatt aaaggtctga
    31741 cagttggaaa cttctataca gtttatttct ttattcgaga gttagctggt ttcttttcaa
    31801 ttcgtctagg aggacaccct cagtttgtca gacctttggt tcaacctatg ggagaagcag
    31861 ctgcagagtc tcaattaggt agaaagttaa cagaggttga agatgagaca ataaaagcgc
    31921 gtgcggctgc gaatgaaaat tttggaaatt tctttgctca aaatacgttt gtaggtgctg
    31981 ggggagtcct cttgataggg ggaacattag atcagttagg ctatgaaagc aattatgcag
    32041 ggattgcttc tacatctatt attgttgctg ttataacact tattgtagtg gggatttaca
    32101 attatttatt tgataaaaaa ttgatatcaa aaaagactag gggaggagaa caaaaatgac
    32161 agagttggca aagcaactat tagagttgac ctatattgtg attggttgtc aatttctcca
    32221 tacagcctat tgtagttata aagataaaac aaacccagtt cgacttggga catctgcatt
    32281 ttggactcta ttgtctatta cgtttatagg tggttcctat atgccaaata tgagtattgg
    32341 tattattgta atcctattat cgctgttaac attgtttaag caagtccgta tcggaacctt
    32401 gccatcctta gatgaaatga aagccaatat tgaatctaac aggttgaaaa ataaaatttt
    32461 tattccagtt atgctgatgg caatacttgc gttggtctta gcgcaaatga ttccagaatt
    32521 tagcaagatt tcgattagcc ttgccgcctt gtttgctaca atttctgttc ttgtgattac
    32581 caatagtcac cctaagagtc tgttatcaga aaataatcga atgactcagc aagtttcaac
    32641 aagtgggatt gttcctcaat tattaggggc tttgggggct atttttactg tagcaggtgt
    32701 tggtgatgtt atctctcatc tgattagcgg tattgttcct tcagatagtc gctttatagg
    32761 agttttggcc tatgttcttg gaatggttct attcacaatg attatgggaa atgcttttgc
    32821 agcattcacc gttattacag caggtgttgg agttcccttt gtatttgctc tgggagctaa
    32881 tccaattgtg gctggtgctc ttgccatgac agcaggttat tgtgggactt tattgacccc
    32941 aatggctgct aattttaacg ctctaccagc agcattgatg gatatgaaag atcagaatgg
    33001 cgttataaag gctcaagcag gtgttgctct agtaatgatt gttattcaca tattcttaat
    33061 gtactttctc gcattttagt aaaggaaaat aaaatgaaaa tattggttac aggttttaat
    33121 ccttttggag gtgaaaagat taatccagct ttggaggctg taaaattatt accatctgag
    33181 attaatgggg ctgaagttcg ctgggtagaa attccaacgg ttttttataa gtcgtcagaa
    33241 gttttagagg cagaaatatt acgatatcaa ccagatgctg tactttgtat tggacaagca
    33301 ggcggcagga ccggcttaac acctgaacga gtggctatta atcaagatga tgctcgcata
    33361 cctgataacg aaggcaatca accaattgat acaccgattc gtattgatgg agcatcggcc
    33421 tattttagta gtttacctat caaagcgatg gtacaagcta tcaaaaaaca gggacttccg
    33481 gcagttgtat ccaatagtgc aggaaccttt gtttgcaatc atttgatgta ccaagctctt
    33541 tatttagtgg ataaaaaatt ccctaatatg agagcaggtt tcatgcatat tccatatatg
    33601 atggaacaag tagtaaataa gccgaatact gcaggaatga gtctatgtga tattgtaaga
    33661 ggcatagagg tagctattga agctattgta gactacaaag ataaggattt gcagttagta
    33721 ggcggtgaga ctcactgata acctaaaaag gatagtcaat tatgcttgtt tactaactat
    33781 taactatgct aaatcaattg aggttgttta cataaaactc tatatcagag aagcctgata
    33841 tagagttttt tcttgctagt tttagaattt tcttgtaaaa tagaaaaagt gaagagaggt
    33901 atgaaatgag caagaaagat aaaaaaatcg aaattcaagt agcggatgcc aaagttaatg
    33961 ttggtaaaga cagttttgaa ggttatacat tgactatcgg taaaaaagtt atcggagaaa
    34021 ttgccgaatt agacggacaa tttgccatta taaagaatgg gaatgtcgat agtttttata
    34081 aaaaattgga aaaagctgtg gaaattttga ttgaaaatta taatttagca aaataagtct
    34141 tgtttttttg aaattttcat gatataatag tccatgttga ttgtaggaga gatagcgaag
    34201 aggctaaacg cggcggactg taaatccgct ccttcgggtt cgggggttcg aatccctctc
    34261 tctccatttc attaatgggg tatagccaag cggtaaggca agggactttg actccctcat
    34321 gcgttggttc gaatccagct accccagttc ttaggtaata atcaagataa aaagcaaaat
    34381 atcttagggt attttatttt tataattgaa agacgtgaat gatatgaaca tgtccttgcg
    34441 ggtgcttagg aaaaaaatta taagtatgtc aagtttaaga aaaacttgat tgttggagga
    34501 ttttttagat gaacgaattt gaagatttgc taaatagcgt tagtcaagtt gagactggtg
    34561 atgttgttag tgctgaagta ttgacagttg atgcgactca agctaacgtt gcaatctctg
    34621 gaactggtgt tgaaggtgtc ttgactcttc gcgaattgac aaacgatcgt gatgcagata
    34681 tcaatgactt tgttaaagta ggagaagtat tggatgttct tgtacttcgt caagtagttg
    34741 gtaaagatac tgatacagtt acataccttg tatctaaaaa acgccttgaa gctcgcaaag
    34801 catgggacaa acttgttggt cgcgaagaag aagttgttac tgttaaagga acgcgtgccg
    34861 ttaaaggtgg actttcagta gaatttgaag gtgttcgtgg atttatccca gcttcaatgt
    34921 tggatactcg tttcgtacgt aatgctgagc gttttgtagg tcaagaattt gatactaaaa
    34981 tcaaagaagt taacgctaaa gaaaaccgct tcatcctttc acgtcgtgaa gttgttgaag
    35041 cagctactgc agcagctcgc gctgaagtat tcggtaaatt ggctgttggt gatgttgtaa
    35101 ctggtaaagt tgctcgtatc acaagcttcg gcgctttcgt cgaccttggt ggtgttgacg
    35161 gattggttca cttgactgaa ttgtcacatg aacgtaacgt atcaccaaaa tcagttgtaa
    35221 ctgttggtga agaaattgaa gtgaaaatcc ttgatcttaa cgaagaagaa ggacgtgtat
    35281 cactttcact taaagcaaca gtaccaggac catgggatgg cgttgagcaa aaattggcta
    35341 aaggtgatgt agtagaagga acagttaaac gtttgactga cttcggtgca tttgttgaag
    35401 tattgccagg tatcgatgga cttgttcacg tatcacaaat ttcacacaaa cggattgaaa
    35461 atccaaaaga agctcttaaa gttggtcaag aagttcaagt taaagttctt gaagttaacg
    35521 cagatgcaga acgcgtgtca ctttctatta aagctcttga agaacgtcca gcccaagaag
    35581 aaggacaaaa agaagaaaaa cgtgctgctc gtccacgtcg tccaagacgt caagaaaagc
    35641 gtgatttcga acttccagaa acacaaacag gattttcaat ggctgatttg tttggtgaca
    35701 tcgaacttta atcaaattga aaattcacaa aatcctttgt ttactaaaca agggattttt
    35761 ctggctcttt gtcaactgta gtgggttgaa gtcagctaag ctcgataaag gacaaaattc
    35821 gtcctttctt ttttgatatt cag
//
LOCUS       DBEJNA010000024        35107 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEJNA010000024 DBEJNA010000000
VERSION     DBEJNA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.24"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            58..1437
                     /gene="bglA"
                     /locus_tag="ACL3JB_001277"
     CDS             58..1437
                     /gene="bglA"
                     /locus_tag="ACL3JB_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0686002.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            1629..3437
                     /gene="glmS"
                     /locus_tag="ACL3JB_001278"
     CDS             1629..3437
                     /gene="glmS"
                     /locus_tag="ACL3JB_001278"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0686003.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEKYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKRALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(3514..3651)
                     /locus_tag="ACL3JB_001279"
     CDS             complement(3514..3651)
                     /locus_tag="ACL3JB_001279"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686004.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            3708..4757
                     /locus_tag="ACL3JB_001280"
     CDS             3708..4757
                     /locus_tag="ACL3JB_001280"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0686005.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLTAGAVNTKKIRLTSAVSILSSMDPIRLFQQYVTIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(4857..8654)
                     /gene="spuA"
                     /locus_tag="ACL3JB_001281"
     CDS             complement(4857..8654)
                     /gene="spuA"
                     /locus_tag="ACL3JB_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0686006.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKSEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            9070..9483
                     /gene="rpsL"
                     /locus_tag="ACL3JB_001282"
     CDS             9070..9483
                     /gene="rpsL"
                     /locus_tag="ACL3JB_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0686007.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            9503..9973
                     /gene="rpsG"
                     /locus_tag="ACL3JB_001283"
     CDS             9503..9973
                     /gene="rpsG"
                     /locus_tag="ACL3JB_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0686008.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            10398..12479
                     /gene="fusA"
                     /locus_tag="ACL3JB_001284"
     CDS             10398..12479
                     /gene="fusA"
                     /locus_tag="ACL3JB_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0686009.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            12583..16974
                     /locus_tag="ACL3JB_001285"
     CDS             12583..16974
                     /locus_tag="ACL3JB_001285"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0686010.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMTPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            17076..17339
                     /locus_tag="ACL3JB_001286"
     CDS             17076..17339
                     /locus_tag="ACL3JB_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0686011.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            17332..17610
                     /locus_tag="ACL3JB_001287"
     CDS             17332..17610
                     /locus_tag="ACL3JB_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0686012.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            17631..17783
                     /locus_tag="ACL3JB_001288"
     CDS             17631..17783
                     /locus_tag="ACL3JB_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686013.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            17805..19046
                     /locus_tag="ACL3JB_001289"
     CDS             17805..19046
                     /locus_tag="ACL3JB_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0686014.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            19056..19286
                     /locus_tag="ACL3JB_001290"
     CDS             19056..19286
                     /locus_tag="ACL3JB_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0686015.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            19509..20231
                     /locus_tag="ACL3JB_001291"
     CDS             19509..20231
                     /locus_tag="ACL3JB_001291"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0686016.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            20448..21782
                     /gene="pepC"
                     /locus_tag="ACL3JB_001292"
     CDS             20448..21782
                     /gene="pepC"
                     /locus_tag="ACL3JB_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0686017.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(21838..22749)
                     /locus_tag="ACL3JB_001293"
     CDS             complement(21838..22749)
                     /locus_tag="ACL3JB_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0686018.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(22773..23576)
                     /locus_tag="ACL3JB_001294"
     CDS             complement(22773..23576)
                     /locus_tag="ACL3JB_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0686019.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(23604..24593)
                     /locus_tag="ACL3JB_001295"
     CDS             complement(23604..24593)
                     /locus_tag="ACL3JB_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0686020.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(24826..25845)
                     /gene="adhP"
                     /locus_tag="ACL3JB_001296"
     CDS             complement(24826..25845)
                     /gene="adhP"
                     /locus_tag="ACL3JB_001296"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0686021.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(26184..26996)
                     /locus_tag="ACL3JB_001297"
     CDS             complement(26184..26996)
                     /locus_tag="ACL3JB_001297"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0686022.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKSFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            27186..28604
                     /locus_tag="ACL3JB_001298"
     CDS             27186..28604
                     /locus_tag="ACL3JB_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0686023.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            28657..29364
                     /locus_tag="ACL3JB_001299"
     CDS             28657..29364
                     /locus_tag="ACL3JB_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0686024.1"
                     /translation="MKEKNMWKELLNRAGWIMVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIIGARKTQLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            29459..30433
                     /gene="folP"
                     /locus_tag="ACL3JB_001300"
     CDS             29459..30433
                     /gene="folP"
                     /locus_tag="ACL3JB_001300"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0686025.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFEILPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRNLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            30435..31757
                     /locus_tag="ACL3JB_001301"
     CDS             30435..31757
                     /locus_tag="ACL3JB_001301"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0686026.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFNSPYLIHYTDQISINGESISEARLEALMADY
                     QSLMGGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            31738..32292
                     /gene="folE"
                     /locus_tag="ACL3JB_001302"
     CDS             31738..32292
                     /gene="folE"
                     /locus_tag="ACL3JB_001302"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0686027.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            32335..33147
                     /gene="folB"
                     /locus_tag="ACL3JB_001303"
     CDS             32335..33147
                     /gene="folB"
                     /locus_tag="ACL3JB_001303"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HGR0686028.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(33192..33509)
                     /locus_tag="ACL3JB_001304"
     CDS             complement(33192..33509)
                     /locus_tag="ACL3JB_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0686029.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            33866..34312
                     /gene="rplM"
                     /locus_tag="ACL3JB_001305"
     CDS             33866..34312
                     /gene="rplM"
                     /locus_tag="ACL3JB_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0686030.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVVNAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            34331..34723
                     /gene="rpsI"
                     /locus_tag="ACL3JB_001306"
     CDS             34331..34723
                     /gene="rpsI"
                     /locus_tag="ACL3JB_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0686031.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
BASE COUNT        10012 a         6845 c         8104 g        10146 t
ORIGIN      
        1 tttttacctt gttttttctg tataatggga gaaatgagta gataaagagg taaatgtatg
       61 ctaagatttc caaaggattt tgtctgggga tcctctactt ctggaccgca aacagaagga
      121 cgtgtagctg gtgacggtaa gggagacaat ctctgggatt actggttcca agtggagcca
      181 aatcgttact ataatgggat tggttcagat aagacatcga ctttttatga aaattgggag
      241 cgggatattg agcttttgtt agagactggt cacacagcct ttcggacttc tattcagtgg
      301 tcacggattt ttccacaagg ctgtggaaaa gtcaaccctc aaggtgtgga tttttatcgt
      361 aaggtctttg aggctattaa ggctaaagga attcgtctgt tagtcaatct ctatcatttt
      421 gatttacctt ttgcccttca agaggatggt gatggttggg aaaataaggc gacagtctca
      481 gcctatgaag actatgctcg tttttgtttt gagacttatg gagatttagt ggatcaatgg
      541 attaccttta acgagcccat cgttcctgta gaatttggtt atttttatga tgcccattat
      601 ccacataagg tggatgcaga ggcagctgtt aaggtagcct atcatacaca attggccagc
      661 agccgggctg ttaaggcttg ccatgaactt ttgcctgatt ccaagattgg gattgtcctc
      721 aacttgacac cggcttatcc acgtagccag catcctgctg atgtcaaggc agctcgtatt
      781 gcggcccttt ttcaggccca atctttctta gatccatctg tcttgggaac ttatccacag
      841 gagttagtag aaatcttgca tgaacacggt cttttacctg atgctacaga ggaagagttg
      901 gaactcattc gtgataatac ggtggacttc cttggtgtga actactatca acctttgcgt
      961 gttatggctc ctcgatttgc taagcatcca gagagtccac tcttaccaga acatttttac
     1021 gagccttatg tgatgcctgg acgtaaaatc aattctcacc gtggttggga gatttatgag
     1081 caagggattt atgacatcgc ccaaaatatc aaggaaaatt atggcaatat tgagtggatg
     1141 ttgactgaga atggtatggg tgttgaaggg gaagaaaaat tccgtcaaga tggaatgatt
     1201 caagatgatt accgtattga ctttgtaaaa ggtcatcttc gtgaacttca ccgtgccatt
     1261 gaagatggtg ccaactgtaa gggctacttg atttggacct ttattgactg ctggtcatgg
     1321 ctcaacagct ataaaaatcg ctatggtttg gtcgaattag acttggaaac gcaagaacgt
     1381 cgtctgaaga aatcaggcca ctggttcaaa gaattaagcg ataataatgg attttaaaaa
     1441 ggactctgac tgattatccc aatcggtcag agttttttgc ttacaggagc ttaatttgaa
     1501 ctataccaat ttttactctt gacaagtgaa agaaacaagt atatactgtt tttgctgatt
     1561 ctataaaaga tgaattagac tataccaatt ttaaggagaa agcacagctt gcctgtgtcg
     1621 tatatactat gtgtggaatt gttggtgttg ttggaaacac aaatgcaact gatattttga
     1681 ttcaagggct tgaaaagctt gaataccgtg gctatgattc tgcgggaatt tttgtcctag
     1741 atggtgctga taaccatttg gtgaaggctg ttggtcgtat cgcagaattg tctgccaaga
     1801 cagctggtgt tgagggaaca actggtatcg gacatactcg ttgggcaact catgggaaac
     1861 caacggaaga caatgctcac ccacaccgat ctgagacaga acgttttgtc ttggttcaca
     1921 atggggtaat tgaaaactac cttgaaatta aagaaaaata ccttgctggg caccacttca
     1981 aagggcaaac agatacggaa atcgccgtac atttgattgg aaaatttgcg gaagaagacg
     2041 gtctctcagt tcttgaagcc tttaaaagag ctcttcatat tatccgtggt tcatatgcct
     2101 ttgccttgat tgactctgaa aatccagatg tcatctatgt agcgaaaaac aaatctccac
     2161 ttttgattgg tcttggggaa ggctacaata tggtctgctc agacgccatg gctatgattc
     2221 gtgaaactaa ccaatacatg gaaatccatg accaagagtt ggtaatcgtc aaggctgata
     2281 gtgtggaagt tcaagactat gatggaaatc gtcgtgagcg tgctagctac actgctgaac
     2341 ttgacttgtc agatatcggt aagggaactt acccttacta catgctcaag gaaattgacg
     2401 agcaaccaac tgttatgcgg aaactcatcc aagcctacac agatgaggct ggtcaagttg
     2461 tcgtagaccc agatatcatt aaggctgttc aagacgcaga ccgcatctac atccttgcag
     2521 ctggaacatc ttaccatgca ggatttgctt ctaagaaaat gttggaagaa ttgacagata
     2581 caccagttga acttggaatc tcatctgagt ggggctacgg tatgccactt ctcagcaaga
     2641 aaccactctt catctttatc agccaatctg gtgaaacagc ggatagtcgt caagttttgg
     2701 tcaaggctaa tgaaatggga attccaagct taacagtgac aaacgttcca ggttcaaccc
     2761 tctcacgtga agccaactat accatgctcc ttcacgcagg tcctgaaatt gccgtggcat
     2821 caactaaagc ctatacagcg caaatcgcag cccttgcctt ccttgcaaaa gcagtcggag
     2881 aagcaaatgg taatgctaaa gcgcaagcct ttgacctggt tcatgaattg tcaatcgtag
     2941 ctcagtctat cgaatcaact ctttcagaga aagaaaccat tgaagccaag gttcgtgaac
     3001 ttcttgaaac aactcgtaac gccttttaca tcggacgtgg tcaagattac tacgtagcca
     3061 tggaagcaag tctcaaactc aaagagattt cttatatcca gtgtgaaggt tttgcggcag
     3121 gagaactcaa gcacggaacc attgccttga ttgaagaagg aacgcctgtt ttggctctct
     3181 tgtcagatcc agttcttgcc aaccatactc gtggaaatat ccaagaggtc gcagcccgtg
     3241 gtgccaaagt cctcactatc gcagaagaga atgtagccaa agataccgac gatatcgtcc
     3301 ttacgaccgt acatccatac ctctcaccaa tttcaatggt cgtaccaacg caattagtcg
     3361 cttactttgc aaccctccac cgtggcctcg atgtggataa accacgtaac cttgctaaat
     3421 cagtaacggt agaataagct aaaaaagtct agttatctag gctttttcta atgagcaaat
     3481 tggttgcttg tacttaagat tcgtgttata ctcttagaaa atctcttcaa accacgtcaa
     3541 cgtcgccttg ccgtaggtat ggttactgat ttcgtcagtt ctatccacaa cctcaaaaca
     3601 ctgttttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
     3661 gaataatttt tcaaattgaa ggacagagat agacaaggag aatcacaatg gtagaattgg
     3721 gaatttcaac atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg
     3781 ctgaacgcat tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggacg
     3841 tatatgggat tggcgagcac catcgggcgg attttgcagt atcagcccca gagattgtcc
     3901 tgaccgctgg ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt
     3961 caagcatgga cccgattcgt ttgttccaac agtatgtcac tatcgatgct ttgtcaaatg
     4021 gacgagcgga gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt
     4081 atgacttgaa agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca
     4141 atgaaaagac caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag
     4201 tttatcctcg tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg
     4261 aatcaacagt gaagattgct caggctggtc taccgattgt atatgctatt attggtggta
     4321 atccacgtta ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggcc
     4381 atgctgacaa agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg
     4441 agcaggcggt gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag
     4501 accgtccgca ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg
     4561 gcgccatgtt tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg
     4621 atttaggatt ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg
     4681 ttctgagagc tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg
     4741 ctatgaaaga ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac
     4801 aaaaattaat cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag
     4861 ttctcttttt tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct
     4921 gcaaatagga gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct
     4981 ggggttgcag gtatattttc cttgctagag ttttctaccg attcgtttcg aaccgcttct
     5041 tttacagatg atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct
     5101 tggctaggtt tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta
     5161 gcttctggag ctgggtcttg atgtgcaggg tgagaagctt cattttgatg ttcaggcttg
     5221 gaaggggttg agtctggttt ctcttctgca gttgactcat ggctagttcc attttgagag
     5281 actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt ccattcaagt
     5341 cctttcgggt tggcaattcc gactgatcct gcttggtttt catctgccaa aacttccgca
     5401 tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc atccgcattg
     5461 acaaagactg cgtagatatc gccgtttgga gcagtgattt ggtagccaat cactacatcc
     5521 tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc tttgatatct
     5581 tggagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa acctttcata
     5641 tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt agtccagtca
     5701 aacttgttga ctgcgtcgct agaatcgtaa gaatcatgga tgaagtaagg atagtcaaat
     5761 gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc ctctgctact
     5821 ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg accggagtgg
     5881 ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa acgacggtgg
     5941 atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc aatgatgtca
     6001 aagagggtca agttatcatg ggctgcgatg tattggatga catctccagg gctgtcagct
     6061 tcaaagttag ttggttgagc aatgagattt ttaaagatgg tgttgacatc acgcttgcca
     6121 cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt gttacggatg
     6181 tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc agcagcttta
     6241 gtaggcatgt tttcatcacc ggcataggtt ctccaacctt caccaagcat gatgaggttt
     6301 ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag aagcggcgtc atggtctccc
     6361 atcatatcga agcggaagcc atccactttg taggtatcaa ctaggtattt gatagagtca
     6421 actaggagcc gtttggtcat atggtgggtt gtccccaagc gtccaccacc aaagctagtt
     6481 cgaggtgtgc catcggcatc cataaagtgg tagtagtttg gctctaggtc ttcaaagata
     6541 tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc acgtttgtgg
     6601 atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt aggatcgctt
     6661 gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt gtagttgctg
     6721 ttgcttgaag cgtagtcaga caagcgttca tggtttttca attcattgac aaagtagtaa
     6781 gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata gtctagtttt
     6841 tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat ggcaggatct
     6901 gaagtgaagt cacgcacatg agcttcgtag ataacggcgt cttcacgagt cttgaaattg
     6961 tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac aaaggcggct
     7021 ttagccactt tatgggcatc gtcaattttg gcatcgtcgc tattccaagc agcaagagat
     7081 ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg gtattgataa
     7141 tagtagccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt ttgtttccaa
     7201 gttcctcttt cccctttttc gagagcgaca gttccaacta ctttgtcagg gtcattcttg
     7261 tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa atcaacttgt
     7321 tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt ctcatctttc
     7381 aggcgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt ataaggatgt
     7441 tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc gattgcaaca
     7501 tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt gaggatatct
     7561 tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt gcctacgtgt
     7621 tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat cgattcatca
     7681 tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata attttcttta
     7741 cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc aaattctctt
     7801 gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc cgtaaagtct
     7861 gttccgtcag gccattgagc gctacttgga ttttttacat ctccccagta ccagagagat
     7921 ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc tgcaggctgt
     7981 ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cctcgttcat ttttggaact
     8041 agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt gatgaggaag
     8101 ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc gtagtcatct
     8161 ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg tttttcaaca
     8221 tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt tttgacatgg
     8281 atacggaagt agttatcttc gatgggctct tctgacttag tttcagttgt tactggacta
     8341 gtagaagtag ttggctctgt tgcaggtttt tcttctgttt tctctaggga agcgtttgca
     8401 tttctaggtg aagaaatatc actttcgttc ttaccagagc cagctgctgt atcagtaaga
     8461 ggttgggcaa gggtggttgt atttctgttg ttgggttcgt tagtggttgg tgtactttcg
     8521 tcggatgaga tagttggtgt agccatggca agcaagacaa ggcttgcgcc gataaggaca
     8581 gaaccagttc catttttgag ggaacggatg ctgtagacca tttttttctc agtgtgagat
     8641 ggtgtttttc tcataatgat tctccaatca ataaatttct atatcagtat agcatgtagt
     8701 aaaacaatat gcaagcgttt tctttgattt gtgaaaaaat tcttactttt gagaagtttt
     8761 ctgtactatt ttatatatca gtataaatga cggagataaa aatgtcacat aagccaagcc
     8821 gtattattag gaagatgatg tgttcccagc tatttttatt cagaaattga tctctaacat
     8881 taccaataaa aaagaaaaat atcttgacaa gcaagggaaa attttgttac aataatagac
     8941 ggtacttttt acttttggtc tctcaagagt gtacagggac gtgctgacaa atgttgcaaa
     9001 agtacacaca gatgatatct gtcaccaagt gtatcatcac caaaaataaa aaaacacagg
     9061 agaatgtaga tgcctacaat taaccaattg gttcgcaaac cgcgtaaatc aaaagtagaa
     9121 aaatctaaat caccagcttt gaacgttggt tacaatagtc ataaaaaagt tcaaacaaac
     9181 gtttcttcac cacaaaaacg tggtgttgca actcgtgttg gaacaatgac acctaaaaaa
     9241 cctaactcag cccttcgtaa attcgctcgt gtacgtttga gcaaccttat cgaagttact
     9301 gcctacatcc caggtatcgg acacaacttg caagagcaca gcgtggtgct tcttcgcggt
     9361 ggacgtgtaa aagaccttcc aggggtacgt taccatatcg tccgtggtgc acttgatact
     9421 gcaggtgtta acgatcgtaa acaaggtcgt tctaaatacg gtactaaacg tccaaaagca
     9481 taaggaaagg ggataaagag aaatgagtcg taaaaataga gctccaaaac gtgacgtatt
     9541 gccagatccg ctatacaatt cacaactagt tactcgtctt atcaaccgcg ttatgcttga
     9601 tggtaaacgt ggtactgctg cttcaatcgt ttacggtgct tttgagcaaa tcaaagaagc
     9661 tactggcaac gatgcacttg aagtatttga aacagctatg gaaaacatca tgcctgtact
     9721 tgaagtacgt gcacgtcgtg ttggtggttc taactaccaa gtcccagttg aagttcgtcc
     9781 agaacgtcgt acaacacttg gacttcgttg gttggtaaca atcgctcgtc ttcgtggtga
     9841 acacacaatg caagaccgtc ttgcaaaaga aatcttggat gctgctaaca acactggtgc
     9901 agcagttaag aaacgtgaag atactcaccg tatggctgaa gctaaccgtg cattcgcaca
     9961 cttccgttgg taagatagga tgcgaaagcg ttaagaaagt cccagagaaa atagggaatc
    10021 gaagcaggtt gcggttgcaa ccaatgagat tcatcttttt ctccagactt ttagcttgag
    10081 ctcaactaaa tcatgatgct aggaacggta aggatgcaag gtgaaaatag gaaactgacg
    10141 cagtattcga cgaatacaag gagttttatc tttttcacgc agcatcccgt tccagctcac
    10201 atcggctaac taactttagc ccgggttcaa attagctaaa tcgattagta ttagctataa
    10261 ctcagcttac catctcgtaa gttgaaacca acaatagcat gaaaacattg agaacgggta
    10321 ggtcctgcct atccgttttt attaaaatcg tgttataata gaatagaaat caaaaataaa
    10381 taggagaaac aaacctcatg gcacgcgaat tttcacttga aaaaactcgt aatatcggta
    10441 tcatggctca cgtcgatgcc ggtaaaacaa caactactga gcgtattctt tactacactg
    10501 gtaaaatcca caaaatcggt gaaactcacg aaggtgcgtc acaaatggac tggatggagc
    10561 aagagcaaga acgtggtatc acgatcacat ctgctgcgac aacagctcaa tggaacaacc
    10621 accgcgtaaa catcatcgac acaccaggac acgtggactt cacaatcgaa gtacaacgtt
    10681 ctcttcgtgt attggatggt gcggttaccg ttcttgactc acaatcaggt gttgagcctc
    10741 aaactgaaac agtttggcgt caagcaactg agtacggagt tccacgtatc gtatttgcca
    10801 acaaaatgga caaaatcggt gctgacttcc tttactctgt aagcacactt cacgatcgcc
    10861 ttcaagcaaa tgcacaccca atccaattgc caatcggttc tgaagatgac ttccgtggta
    10921 tcattgactt gatcaagatg aaagctgaaa tctatactaa cgaccttggt acggatatcc
    10981 ttgaagaaga catcccagct gaataccttg accaagctca agaataccgt gaaaaattga
    11041 ttgaagcagt tgctgaaact gacgaagaat tgatgatgaa atacctcgaa ggtgaagaaa
    11101 tcactaacga agaattgaaa gctggtatcc gtaaagcgac tatcaacgtt gaattcttcc
    11161 cagtattgtg tggttcagcc ttcaaaaaca aaggtgttca attgatgctt gatgcggtta
    11221 tcgactacct tccaagtcca cttgacatcc cagcaatcaa aggtattaac ccagatacag
    11281 acgctgaaga aactcgtcca gcatctgacg aagagccatt tgcagctctt gccttcaaga
    11341 tcatgactga cccattcgta ggtcgtttga cattcttccg tgtttactca ggtgttcttc
    11401 aatcaggttc atacgtattg aatacttcta aaggtaaacg tgaacgtatc ggacgtatcc
    11461 ttcaaatgca cgctaacagc cgtcaagaaa tcgacactgt ttactcaggt gatatcgctg
    11521 ctgccgttgg tttgaaagat actacaactg gtgactcatt gacagatgaa aaagctaaaa
    11581 tcatccttga gtcaatcaac gttccagaac cagttatcca attgatggtt gagccaaaat
    11641 ctaaagctga ccaagacaag atgggtatcg cccttcaaaa attggctgaa gaagatccaa
    11701 cattccgcgt tgaaacaaac gttgaaactg gtgaaacagt tatctcaggt atgggtgaac
    11761 ttcaccttga cgtccttgtt gatcgtatgc gtcgtgagtt caaagttgaa gcgaacgtag
    11821 gtgctcctca agtatcttac cgtgaaacat tccgcgcttc tactcaagca cgcggattct
    11881 tcaaacgtca gtctggtggt aaaggtcaat tcggtgatgt atggattgaa tttactccaa
    11941 acgaagaagg taaaggattc gaattcgaaa acgcaatcgt cggtggtgtg gttcctcgtg
    12001 aatttatccc agcggttgaa aaaggtttgg tagaatctat ggctaacggt gttcttgcag
    12061 gttacccaat ggttgacgtt aaagctaagc tttatgatgg ttcatatcac gatgtcgact
    12121 catctgaaac tgccttcaag attgcggctt cactttccct taaagaagct gctaaatcag
    12181 cacaaccagc tatccttgaa ccaatgatgc ttgtaacaat cactgttcca gaagaaaacc
    12241 ttggtgatgt tatgggtcac gtaactgctc gtcgtggacg tgtagatggt atggaagcac
    12301 acggtaacag ccaaatcgtt cgtgcttacg ttccacttgc tgaaatgttc ggttacgcaa
    12361 cagttcttcg ttctgcatct caaggacgtg gtacattcat gatggtattt gaccactacg
    12421 aagatgtacc taagtcagta caagaagaaa ttattaagaa aaataaaggt gaagactaat
    12481 ccgtcctcac tctagaagga agtcacttag tggcttcctt ttgtctttag aaaatacctc
    12541 taaatatggt aaaatagtag aagaataatg tgaggaaaat gaatgtcaaa tagttttgaa
    12601 attttgatga atcaattggg gatgcctgct gaaatgagac aggctcctgc tttagcacag
    12661 gccaatattg agcgagttgt ggttcataaa attagtaagg tatgggagtt tcatttcgta
    12721 ttttctaata ttttaccgat tgaaatcttt ttagaattaa agaaaggttt gagcgaagaa
    12781 ttttctaaga caggcaataa agctgttttt gaaattaagg ctcggtctca agaattttca
    12841 aatcagctct tgcagtccta ctatagggaa gctttctctg aaggtccatg tgctagtcaa
    12901 ggttttaagt ccctttatca aaatttgcaa gttcgtgctg agggtaatca gctatttatt
    12961 gaaggatctg aagcgattga taaggaacat tttaagaaga atcatcttcc taatttagcc
    13021 aaacaacttg aaaagtttgg ttttccaact tttaactgtc aagtcgagaa gaatgatgtc
    13081 ctgacccaag agcaggaaga ggcctttcat gctgaaaatg agcagattgt tcaagctgcc
    13141 aatgaggaag cgctccgtgc tatggaacaa ctggagcaga tgacacctcc tccagcggaa
    13201 gagaaaccag tctttgattt tcaagcgaaa aaagctgcag ctaaacccaa gctggataag
    13261 gcggagatta ctcctatgat cgaagtgacg acagaggaaa atcgtctggt atttgaaggg
    13321 gttgtttttg atgtggagca aaaagtgact agaacaggtc gtgttttaat caactttaaa
    13381 atgacggact atacttcaag tttttctatg caaaagtggg ttaaaaacga ggaagaggcc
    13441 cagaagtttg acctcatcaa gaagaattct tggctccgag ttcgagggaa tgtggagatg
    13501 aataacttca cacgcgattt gactatgaac gtacaggatc tgcaggaagt tgttcactat
    13561 gagcggaagg atttgatgcc agaaggtgag cgtcgggttg agtttcatgc tcatactaac
    13621 atgtcgacta tggatgcttt gccagaggtc gaagagattg ttgcaacagc tgctaagtgg
    13681 ggacacaagg cggttgctat cacagaccat gggaatgtcc agtcctttcc acatggctat
    13741 aaggcggcta agaaagcggg aatccagctg atctatggga tggaagccaa tatcgtggag
    13801 gaccgtgtcc ctatcgtcta taacgaagtg gagatggact tatcagaagc aacctacgtg
    13861 gtctttgacg tggaaacgac gggactttca gctatctata atgacttgat tcaggttgcg
    13921 gcctctaaga tgtacaaggg gaatgttatt gctgaatttg atgaatttat caatcctggg
    13981 catcccttgt cagcttttac tacagagtta actggaatta cagatgatca tgtcaaaaat
    14041 gccaaaccac tagaacaagt tttgcaagaa ttccaagaat tttgcaagga tacggtccta
    14101 gttgcccaca atgctacctt tgacgttggc tttatgaatg ctaattatga gcgtcatgat
    14161 cttccaaaga ttagtcagcc agttattgat acgctggagt ttgctagaaa cctctatcct
    14221 gagtataaac gccatggttt ggggcctttg accaagcgtt ttggtgtggc cttggaacat
    14281 caccacatgg ccaactacga tgcggaagcg actggtcgtc tgcttttcat ctttatcaaa
    14341 gaggtagcag aaaaacatgg tgtgaccgat ttagctagac tcaacattga tctaatcagt
    14401 ccagattctt acaaaaaagc tcggatcaag catgcgacca tctatgtcaa gaatcaggta
    14461 ggtctaaaaa atatctttaa gctggtttcc ttgtctaata ccaagtattt tgaaggagtg
    14521 tcacggattc cgagaacggt tctagatgcc catcgagagg gcttgatttt aggttcagcc
    14581 tgttcagagg gtgaagtttt tgacgtggtc gtttctcaag gtgtggatgc ggcggttgag
    14641 gtggccaagt attatgactt tatcgaggtc atgccaccgg ctatctatgc gcccttgatt
    14701 gctaaagagc aggtcaagga tatggaggaa ctccagacca ttatcaagag tttgatagag
    14761 gttggagacc gccttggcaa gcctgttctg gctacgggaa atgttcacta tatcgaaccg
    14821 gaagaagaga tttatcgtga aattatcgtc cgtagtttgg gacagggtgc gatgattaac
    14881 cgaactatcg gtcatggtga acatgcccaa ccagcaccac ttccaaaggc tcattttcga
    14941 acgactaatg agatgttgga tgaatttgcc tttttgggag aggaactggc tcgtaaactg
    15001 gttattgaaa acaccaatgc cttggcagaa atatttgaac ccgttgaagt cgttaagggt
    15061 gacttgtata cgcctttcat cgacaaggct gaagaaacag ttgctgagtt gacctataag
    15121 aaagcttttg agatttatgg aaatccgctg ccagatattg ttgatttgcg gattgaaaaa
    15181 gaattaacat ccatactggg gaatggattt gctgtgattt atctggcatc gcagatgctg
    15241 gtgcaacgtt ctaatgaacg gggttatttg gttggttctc gtgggtctgt cggatctagt
    15301 ttcgttgcga ccatgattgg gattacggag gtcaatcctc tctctcctca ctatgtctgt
    15361 ggtcagtgtc agtacagtga gtttatcaca gatggttcgt acggctcagg atttgatatg
    15421 ccccataagg actgtccaaa ctgtggtcac aaactcagta aaaacggaca ggatattccg
    15481 tttgagacct tccttggttt tgatggggat aaggttcctg atattgactt gaacttctcg
    15541 ggagaagatc agcctagcgc ccacttggat gtgcgtgata tctttggtga agaatatgcc
    15601 ttccgtgcgg gaacggttgg tacggtagct gccaagactg cctatggatt tgtcaagggt
    15661 tacgagcgag attatggcaa gttttatcgt gatgcagaag tagaacgcct cgctcaagga
    15721 gcggcgggtg tcaagcggac aacaggccaa cacccggggg gaatcgttgt tattccgaac
    15781 tatatggatg tctacgattt tacgcctgtc cagtatccag cagatgatgt cacggctgaa
    15841 tggcagacca ctcactttaa cttccacgat atcgatgaga acgtcctcaa actcgatgta
    15901 ctggggcatg atgatccgac catgattcga aaacttcagg atttgtctgg tattgaccct
    15961 aatgaaattc ctatggatga cgaaggcgtg atggcactct tttctgggac tgatgtgcta
    16021 ggggtaacac ctgaacaaat tggaacgcct acgggtatgt tggggattcc agagtttgga
    16081 acaaatttcg tacgtggaat ggtagacgaa acccatccga caacctttgc ggaattgctt
    16141 cagctgtctg gtctgtccca cggtactgac gtttggttgg ggaatgctca ggatctgatt
    16201 aagcaaggaa tagcggacct atcgactgtt atcggttgtc gggacgacat catggtttac
    16261 ctcatgcatg cgggtctgga acctaagatg gcctttacca ttatggaacg ggtacgtaag
    16321 ggtttgtggc taaagatttc agaagaggag agaaatgact atatcgaagc catgaaggct
    16381 aataaggtgc cagagtggta tatcgaatcc tgtgggaaaa ttaagtacat gttccctaag
    16441 gcccatgcgg cagcctacgt tatgatggcc ttgcgtgtag cttacttcaa ggttcaccat
    16501 cctatttatt actactgtgc ttacttctcc attcgtgcta aggcttttga tatcaagacc
    16561 atgggtgcgg gcttggaggt catcaagcgc agaatggaag aaatctctga aaaacggaag
    16621 aacaatgaag cctctaatgt ggaaatcgat ctctatacaa ctcttgagat tgtcaatgag
    16681 atgtgggaac gaggtttcaa gtttggtaaa ttagatctct actgtagtca ggcgacagag
    16741 ttcctcatcg acggggatac ccttatccca ccatttgtag caatggatgg tctgggagag
    16801 aacgttgcca agcaactggt gcgggcgcgt gaagagggag aattcctctc taaaacagaa
    16861 ctacgcaagc gtggtggact ctcatcaacc ttggttgaaa agatggatga gatgggtatt
    16921 cttggaaata tgccagagga taaccagttg agtttgtttg atgagttgtt ttaaaaaatt
    16981 gcttaataat ctattaaaag aggctaacgt atatccaata gatttacatt agctttcttt
    17041 tttgttaaaa tagtctatgg aaagagggtg agagtatgtc aaagatgagt ataagcatcc
    17101 gtctggatag tgaggttaag gagcaggccc aacaggtgtt tagtaatctg ggaatggata
    17161 tgacaacagc tattaatatt ttccttcgtc aggcaattca atatcaggga ttaccttttg
    17221 atgttagact agacgaaaat cggaagttgc tccaagtgtt aacggattta gaccaaaatc
    17281 gtaatatgag ccagtctttt gaatcagtct cagatttgat ggaggactta cgtgcttaag
    17341 attcgttatc ataaacagtt taaaaaagat tttaagttgg ctatgaagcg tggtttgaag
    17401 gcagaattat tagaagaagt tttgaatttt ctggttcaag aaaaagaaca tcctgccaga
    17461 tatcgtgatc attcattgac ggcatccaag cattttcaag gagttcgtga atgccatacc
    17521 cagccagatt ggcttttggt ttataaagta gacaagtcgg aattgatttt aaatttgctg
    17581 aggacaggca gtcacagtga tttattttaa tctattttaa gggggttctc atgaaactaa
    17641 gaatatttgc ggaagataag ccggctaaga aggtatttga atatcaatta gaacttgctg
    17701 atcgtacaat tcttctatcg acagcactct tgtcaggtgc tattgcttta gcaggaatct
    17761 tttctgcttt gagagaaaaa taaaaataga aaagagaaaa cagaatggtt ttaccaaatt
    17821 ttaaagaaaa tctagaaaaa tatgcgaaat tgttggttgc gaacggaatt aacgtgcaac
    17881 ctggtcacac tttggctctc tctattgatg tggagcaacg tgaattggca catctaatcg
    17941 tgaaagaagc ttatgccttg ggtgcgcatg aggtcatcgt tcagtggaca gatgatgtga
    18001 ttaaccgtga gaaattcctc catgccccga tggagcgttt ggacaatgtg ccagaataca
    18061 agattgctga gatgaactat ctcttggaga ataaggctag ccgtcttgga gttcgttcat
    18121 ctgatccagg tgccttgaac ggagtggacg ctgacaagct ttcagcttct gctaaagcta
    18181 tgggacttgc catgaagcct atgcgtatcg caactcaatc taacaaggtt agctggactg
    18241 tagcagctgc agcaggactt gagtgggcta agaaagtctt cccaaatgct gcgagcgacg
    18301 aagaagcagt tgatttcctt tgggaccaaa ttttcaaaac ttgccgtgtc tacgaagcag
    18361 atcctgttaa ggcctgggaa gagcatgcag ctatcttgaa gagcaaggcc gatatgctta
    18421 ataaggagca attttcagcc cttcactaca cagcgccagg aacagattta acacttggtt
    18481 tgccaaagaa ccacgtttgg gaatcagctg gtgctgtcaa tgcacagggc gaaggattct
    18541 tgccaaatat gccgacagaa gaggtcttca cagcgcctga cttccgtcgt gcagatggtt
    18601 atgtcacttc tacaaaaccg cttagctaca acggaaatat catcgaaggt attaaggtaa
    18661 cctttaagga tggacaaatc gtagatatca ctgctgagaa gggtgatcag gttatgaaag
    18721 accttgtctt tgaaaatgcg ggtgcgcgtg ccttgggtga atgtgccttg gtaccagatc
    18781 caagtccaat ttctcagtca ggcattacct tctttaacac ccttttcgat gaaaatgcgt
    18841 caaaccactt ggctatcggt gcagcctatg cgactagcgt cgttggtgga gcagagatga
    18901 gtgaagaaga gcttgaagct gcgggactta accgttcaga tgttcacgtg gattttatga
    18961 ttgggtctaa tcagatggat atcgatggta tccgtgagga tggaactcga gtacctcttt
    19021 tccgtaatgg gaattgggca aattaaggag ataatatgtt aggaagtatg ttcgttggtc
    19081 tcctagtggg atttttagca ggtgctatga ccaatcgtgg agagcgaatg ggatgttttg
    19141 gaaaaatgtt tctcggttgg atcggagcct ttctaggtca cttgctcttt ggaacttggg
    19201 ggccagtttt atcaggaaca gctattatcc cagctgtttt aggtgccatg attgtcttag
    19261 ctattttttg gagacgagga agttaatttc ctaaatctga tactcaatga aaatcaaaga
    19321 gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg cagatagaac
    19381 tgacgaagtc agtaacatat atacggcaag gcgacgttga cgcggtttga agagattttt
    19441 gaagagtatg aaacgaaaag gaggttggtc attgtactag cctccttttg atatgatata
    19501 atagttctat gagattagat aaatttttag ttgcctgtgc ggtgggaagt cggactgagg
    19561 tcaaaaactt gctcaaggct gggcgcgtga ctgtaaatgg taaaaaagaa aaatcagcta
    19621 aattgcagat tgatgaaaaa atagatgaga ttcgctttga tgggcaagtg ttggagtatg
    19681 aagagtttgt ctactacatg atgaacaagc ccaaaggagt tatctcagcg actgaggatc
    19741 ccaagcacag aaccgttctg gacttgttgg atgacttggc gcggagtaag gaagttttcc
    19801 cagtaggacg cttggatatt gacacgcatg gtcttttgct cttgaccaat gatggtcagc
    19861 tggctcatgt tcttctttcg cccaagcgtc atgtggacaa gacttatctg gcacaagtca
    19921 agggaatcat gacccaagaa gatgtggaga catttgctga gggtattcct ctcaaagact
    19981 ttacctgtca acccgctata ctggagcttg tatccataga tacagaaaag aatcaaagcc
    20041 aaatccgtgt gaccattgca gaagggaagt ttcatcagat caagcgtatg gtgggctact
    20101 gtggcaagga agtggtggac ttgcaacgat tgactatggg aactttagta ttagatgaga
    20161 acctggaacg aggggaatgg cgtcgcttga ccaaggaaga attagaaatt ctccgcgcta
    20221 atattattta atttagttta atactcaatg aaaatcaaag agcaaactag gaaactagcc
    20281 gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga
    20341 gtataaattc gaaaaaggtg agggacaatg tcctcgcctt ttatgttttt tagttgcttc
    20401 ctttgtgaaa agagttataa tagactgtag aataaaagga ggaatctatg aacgcgattc
    20461 aagaatcatt tactgataaa ctatttgcca actatgaagc aaatgtaaaa taccaagcga
    20521 ttgaaaatgc tgccagccac aacggaattt ttgcagctct ggaacgtcgc caaagccatg
    20581 tagacaacac acctgttttc tcattggatt taaccaagga caaggtcact aaccagaaag
    20641 cgtctggtcg ttgctggatg tttgcggctc tcaacacctt ccgccacaaa ctcatctcgc
    20701 aatacaaatt ggagaacttt gagttgtcac aagcccacac tttcttctgg gacaagtatg
    20761 agaaatcaaa ctggttcttg gagcaagtca ttgcgacttc agaccaagaa ttgactagcc
    20821 gcaaggttag cttcttactc caaacacctc aacaagatgg cggtcaatgg gatatggtcg
    20881 tttccctctt tgaaaaatac ggtgtcgtgc ctaagtcagt ttatcctgag tctgtttcat
    20941 ctagcagcag tcgtgagcta aatgcgatcc ttaataaatt gcttcgtcaa gatgctcaaa
    21001 tcttgcgtga tttgcttgtt tctggtgcag atcaagcgac tgttcaagct aagaaagaag
    21061 acctcttgca agaaatcttt aactttcttg ctatgtcatt aggacttcca ccacgcaagt
    21121 ttgactttgc ttatcgcgat aaagataaca actacaaaag tgaaaaagga atcacaccac
    21181 aagagtttta caagaaatat gtcaatcttc ctttagaaga ctacgtttct gttatcaatg
    21241 ctccaactgc tgataaacct tacggaaaat cttacacagt tgagatgttg gggaatgtgg
    21301 ttggtagccg tgcagttcgc tacatcaacg ttccaatgga gcgcttgaaa gaattggcga
    21361 ttgcccaaat gcaagcaggt gagactgttt ggtttggttc tgatgtcggc cagctcagca
    21421 accgtaaggc tggcatcctt gcgacagatg tttatgactt tgaatcaagc atggacatta
    21481 aacttactca agacaaggct ggacgtttgg actatagtga aagcttgatg acccacgcca
    21541 tggtcttgac aggtgttgac ttggacgaaa atggtaaatc aaccaagtgg aaggttgaaa
    21601 actcatgggg agacaaggtt ggtacagatg gttactttgt tgcctcagac gcttggatgg
    21661 acgaatacac ataccaaatc gttgttcgta aggaattgct gacagcagaa gaacaagctg
    21721 cctatggagc agaaccaatc gtacttgcac catgggatcc aatgggagcc ttggctgaat
    21781 aaaagcatag aaaaaaggaa tcagatttta gaacctggtt cctttttagt tgcttgatta
    21841 catgatgtga agaacatgtg ccacaatacc cactgcgaag agggcaagga taatagtgat
    21901 tggagatact tttttcttaa gtaagtacat gcaaagtaaa gtaaggagta gtcctgataa
    21961 tccaggaatc aacatatcca agttttgttg gaaagtagta actttttcag gagtttgaga
    22021 caatccttgt cctacttgtg cgaatgcttc ttggatacct ttagaccctt ctggcaattt
    22081 atcccaatgg atataagcct tttcatctag ttgaacttta gaaacatcga aagcaaattt
    22141 aatatttacc caacgttgaa caaggacagc aagaatgaac atcccaagga tagaagctcc
    22201 tttagtgata tcttgaagga taccaccaga catatcttta gtgatttctg atccagcctt
    22261 gtatccaatc tcttgaacat accacaagaa tgacatacga atcaagttcc atgcaacaaa
    22321 gaagaggagt ggccccaaga tattgccagt aagggcaagt gaagcaccga gagatccaag
    22381 gattgggcgt actgtaaacc agaatactgg gtcaccgata ccagcaagag gtcccatcat
    22441 accgatttta accccttgga tagcagcgtc atcgatttcc acaccgttag cacgttcttc
    22501 ttcaagcgca agagtaaccc ccatgactgg agcagctacg tatggatgag tgttgaagaa
    22561 ctcaaggtga cgctcaagag cagcgatttg atcttctttt ttagtataga gttttttgat
    22621 agctggaatg agtgtataag cccagcccaa gttttgcatc cgttcaaagt tccaagaccc
    22681 ttgtaagaag gttgaacgcc accaaacttt tttacgatct gatttagtta attgaagttt
    22741 ttcagtcatg atgttttcag tcctttctta tcttagtagt cttctaggat atcgccgatt
    22801 gggtcgttag aagttgcggc tcctccgcca ccatttccac cagttttaga aaggtgaagg
    22861 tagataagag cgatagcaac accgatagca ccgaatccga ttagagtaat atctgacaca
    22921 gcagcgagaa cgaaaccaag agcgaagaat ggccatactt cacgagttgc catcatgttg
    22981 ataaccatgg cgtaaccaac ggcaacgacc ataccaccac cgatagccat accatctttg
    23041 agccagtctg gcatggcact aaggatactt tgtacagttt cagttggtac cataaggaga
    23101 agagctgcag gaagcgcgat acgaagtcct tggaaaagta gcgcaatgaa atgagcacgc
    23161 tccacagcgc cgaagtcacc ttttttagcg gcagcatcag cagtgtgaac caatccaact
    23221 gaaattgtac gaacaatcat agttaagaat agaccagcta cggcaagagg gatagcaacc
    23281 gcttgggcaa caccgatacc agtcttggta aagtcaccac caagaaccat gataatggca
    23341 gcagcgacag aagcaagtgc agcatcagga gcgatagcag caccgatatt tgaccaacca
    23401 agggcaatca tttgaagcga tccaccgagg ataatccctg cttccaagtg acctgttaca
    23461 agcccaataa gggtacaggc tacaagtggt tggtgaaatt ggaactggtc gaggatgcct
    23521 tcaagacctg caaagaaggc tacaacgact actaaaacca tagaaataat agacatgttt
    23581 aaaatccttt cataaataat ggcttatttg acattggctt tgttaatcaa gtcaaacaaa
    23641 tcttttttag aatcatttgg tactttacgg acatcaaatt caacacccaa gtcacgcatt
    23701 ttttcaaatg tagcaacatc ttctttgtcc atagacaaaa cggtattgac caatgtttta
    23761 cctgttgagt gagccataga accaacgtta agagtcttga ttggcacgcc gccttcgatg
    23821 gcacgaaggg catcttgagg tgtttcaaac aagataaggg catgtgtttc tccaaaacgt
    23881 gggtcttttg aaatctcaat cagtttttga attggaacca cgttagcctt gacattacct
    23941 ggagctgctt gtttaatcaa ttctttacga aggtcgtctt tagccacgtt atctgaagca
    24001 acgatgatac gatttgcttt tgaatctgga gtccaagcag ttgcaacctg accgtgaagt
    24061 agacgtgtgt caagacgggc aagattgatt ttcaatttac cgtctccgat aacagttcct
    24121 tctgggatag cagtttgggc aactggagca gctgcagcgc ttgcaacttc ttcaactgga
    24181 tttagctctt ctggaagagc tttgatgcca tctttggctt ctttaatgat attagcagcg
    24241 actttttcta cacctgcagc agcgtccatg aggcgctctg tgtaggcttg aatcaacatc
    24301 ggtaagttaa gtcctgtgat gatggcaaac ttacgctcag gattttctcc catcacgcga
    24361 ctagcttggt taaatggaga accactccaa aggtcagcca aaactagaac ctcatcttct
    24421 gcgtcaaatg cagcaacagc gttattaaac ttagcgtata gatcatcagg accttcattt
    24481 ggcataaagg tcacaacttg aaccttttct tgttcaccaa agatcataga tcctgactga
    24541 tgaatacccg cagcaaattc gccgtggctc gcaataatga ttccgatact cattattgtc
    24601 attcctcctt ttttgtttta gttttcattt aagaaaactt taagactgtt taagtataaa
    24661 ccgttttcat aaaaaaagca actatttatc ataaaaaatt aaaaaatttt tatttttgta
    24721 tgttgatatg ttgagttttt gaggagtaat cttgaattct tatttaaaat ttaatataaa
    24781 aaagttggaa gaagcttcca acttttaaaa taggtttcta ttagattagt gggtgaagtc
    24841 gagtaccata cgtccttgga tttggccttt ttccatttcg tcgaaaatgg caacagcatc
    24901 ttctactgga cgtttttgaa caactgggac taccagacct tctgcaccaa attggaaggc
    24961 ttcttctaag tctttacgag ttccgacaag agaaccgatg acttggattc catcgaggac
    25021 tgttttaacg atgctgagtt ccatcatttc agaaggaaga ccaacagcga cgacgcgacc
    25081 accagcacga atggagtcaa cagcctggtt gaaggcaact ttagacacag cagttacgac
    25141 agctgaatga gctcctccat cagttttttc tttaatgagt ccagctacat cttcaacttc
    25201 gaggccgtta atcacaatgt cagcgcctac ttcttttgca agggcaagtt tgtcattgtt
    25261 gatatcgact gcgataacat gagcattgaa tactttttta gcgtattgaa cagcgaggtt
    25321 accaagtcca ccagcaccgt aaagaacaac ccattggcct ggttcaactt ttgcttcttt
    25381 gatagcttta taggttgtta ctccagcaca tgtgatagaa gaagcttggg ctggatcaag
    25441 tccgtcagga actttgacag catagtcagc agttacgata cattgttcag ccataccacc
    25501 gtctactgag tagccagcat ttttcactgt acggcaaagg gtttcgcgac cagttgtaca
    25561 gtattcgcaa gtgccacatc cttcaaagaa ccaagcaacg ctgacgcggt caccgacttt
    25621 aaggcttttc acatctggag caatctcttt aacgataccg ataccttcgt gcccaagaac
    25681 acgtcctggg acttgaccaa agtcaccatg agcaacgtgg aggtcggtgt ggcaaacacc
    25741 acagtattca acttctacaa gtgcttcccc agtttcaagt ggacggagta ctttttcttc
    25801 aatagcaaca ccagtgcttt ctggatttac aacaacagct ttcatagcta tcctccttga
    25861 tattgaccga gaacagggac aacgggactg gattgatttt ttgtcaacag agtcgagtgt
    25921 gacgagctct cttgtattta tatgtgaagt atatcacaaa agaaagcctt ttccaaggtt
    25981 ttggagacaa aaagtagaac aatcgattaa ctggttgatg agactgtgaa aagagcacaa
    26041 agaccagctt gcaagctggt catactcttc gaaaatctct tcaaaccacg tcagcttcat
    26101 ctacaacctc aaagcagtgc tttgagcaac ctacggctag cttcctagtt tgctctttga
    26161 ttctcattga gtatcagtat aggttataag aataagtctt gtagggtttt ggcaacccca
    26221 tcttggtcgt tggtaaggga aatttgctca tctgcataag ggagtagctc tggattggca
    26281 tttttcatgg cataaccctt cccagcaaaa gcgagcattt cggtatcatt gtgttcatct
    26341 ccaaaggcaa tcaaatcttt tttgtcacga ttcattatct tgagcaagta gtccaaagca
    26401 aaggacttgt tgacaccttt tggggtacat tcaaggatat tgagcggacc tccccaggta
    26461 ttgatagaaa gttgatgctg gtagaaggcg ttcatttctt ttgccaaggc atatttgtca
    26521 ctggctctgg tctgcaagag gatacagtta gggtccttgg tcaccaattc aggctggaat
    26581 tgatcttcag gctggaaagc ttctacacca aatagtttgg gattggcaat ttcttcattg
    26641 ggatttgtaa tgtagaattt tttacgatat tctccagcga taaaatcggc ttgaatgtcc
    26701 tctgaacgtt gaaccatatc tagcagatat tttttgtcta cagtcaaaca cttttcaaaa
    26761 tcccaaactt ggtctggtaa atgagtaagg gatccgttga agttaatcat aggagtgtct
    26821 aagcccagtt cacggtaaaa atcttttgac atacggtaag ggcgacctgt cgtaataata
    26881 acctgatggc ctttttcagc aacttttttg atggttcttt tggtaaagtc agaaatttga
    26941 ctgtctgagt tgagcagggt tccatccagg tcaactgcaa taattttttt cgtcatatgg
    27001 acctttctag tgtgttttca gataagatgt cttctattat aacagaaagc aggcagaaaa
    27061 gcagattcca aacaaaaaat gaaattggat taatttctta aacaaatcaa acaaagacat
    27121 tgaaaaagtg aatgataaat gatataattc tattattgtt cgtaaaaatt aaaaggagat
    27181 tgatgatgga caaattattt aaactaaaag agaacggtac agacgttcgt acagaggttc
    27241 tcgctggttt aacaactttc tttgcaatga gctatattct ctttgtaaac ccacaaatac
    27301 tttcacaaac aggaatgcct gctcagggcg tcttcctagc gacgattatt ggtgcagtag
    27361 cgggtacctt gatgatggct ttttatgcta acttacctta tgcccaagcg ccaggtatgg
    27421 gactcaatgc cttctttacc tttacagttg tattcgggct tggttattct tggcaagaag
    27481 ccctagctat ggtcttcatc tgtgggatta tttcattgat tattaccttg acaaatgttc
    27541 gtaaaatgat cattgaatcg attcccaatg ctcttcgctc agctatttca gctggtatcg
    27601 gtgtcttcct tgcctatgta gggattaaga atgctggact tttgaaattc acgattgatc
    27661 caggcaacta tactgttgta ggagaagggg ctgacaaagc tcaagcaacg attgcagcaa
    27721 actcttcagc agttccagga ttggtcagct ttaataatcc agctgtttta gtggctcttg
    27781 caggacttgc cattactatc ttctttgtca tcaaagggat taaaggggga attattctct
    27841 ctatcttgac aacaactgtt cttgctattg cagttggttt ggttgatttg tctagtatcg
    27901 attttgctaa taaccatgtt ggtgcagctt ttgaagattt gaagacaatc tttggtgcag
    27961 ctcttggttc agaaggtttg ggagctttgg tttcagatac agctcgcttg cctgaaactc
    28021 tgatggccat tcttgccttc tcattgacag atatttttga cacaattggt accttgatcg
    28081 gtacaggtga aaaagttggt atcgtagcga caaatggtga aaatcaccaa tcagccaaat
    28141 tggataaggc tctttactct gatttgattg gaacgacagt cggtgctatt gcaggtactt
    28201 caaacgtaac gacttatgtt gagtctgctg ctggtatcgg tgcaggtgga cgtactggtt
    28261 tgacagcctt ggttgtagct atctgttttg cgatttcaag cttctttagc ccacttctag
    28321 cgatcgtacc aacagcggct acagctccaa tcttgattat cgttgggatt atgatgcttg
    28381 gtagcttgaa aaatatccat tgggatgata tgtctgaagc agttcctgcc ttcttcacat
    28441 ctatctttat gggattcagc tactctatca ctcaagggat tgcagttggt ttcttgactt
    28501 acactttgac taagcttgtt aaaggtcaag ttaaagatgt tcatgccatg atttggattt
    28561 tggatgcctt gtttatcctt aactacatca gcatggcctt ataatagaat gacccagggg
    28621 gatttccccc cttttttaat acaaaggaga taggtgatga aagagaaaaa tatgtggaaa
    28681 gaattgttga atcgtgcagg ctggattatg gtctttttac ttgccgtcct tttatatcag
    28741 gttcccctag tggttacctc tattttgact ttaaaagaag tagccctgct acagtcaggg
    28801 ctgatagttg ctggcctttc aattgtggtt ctggctctat ttattattgg agctcgtaaa
    28861 acgcaattgg caagttttaa tttttctttt tttagagcta aagatttggc acgtttgggc
    28921 ttgagttatt tagttattgt cgggtcaaat atacttggtt ctatcttgtt gcaactgtca
    28981 aatgagacga caacagctaa ccagtctcag attaacgata tggttcaaaa tagttcgttg
    29041 atttccagtt tcttcttgct agccttgctt gctccgattt gtgaggaaat cttgtgccgt
    29101 gggattgttc ctaaaaagat tttccgaggc aaggagaact tgggatttgt agtcggtacg
    29161 attgtgtttg ctttattgca tcaaccaagt aatttacctt ctttattgat ttatggaggt
    29221 atgtcgacag ttctatcttg gacggcctac aagacccaac gtttggaaat gtcgatcttg
    29281 cttcacatga ttgttaatgg gattgctttc tgtttgttgg ctcttgtggt gattatgagt
    29341 cggacattag gaatttctgt gtaaaagttt ttatgtagga accgacctct ttctactagg
    29401 gaaagatgaa tgcaatcgtg tccatctttt tctttttatg gtaaaataga aaaataatat
    29461 gatgaaaatc cttgagggag tgaccgatat gtcaagtaaa gccaatcatg caaagacagt
    29521 tatttgcgga attatcaatg taaccccaga ctccttttcg gacggtggtc aattttttgc
    29581 tcttgagcag gcactccagc aggctcgtaa attgatagca gaaggagcca gtatgctcga
    29641 tatcggcgga gaatcgactc ggccgggcag tagctatgtt gagatagaag aggaaatcca
    29701 gcgtgttgtt ccagtgatca aagcgattcg caaggaaagt gatgtcctca tctctattga
    29761 tacttggaag agtcaagtag cagaggctgc tttggctgct ggtgccgatc tagtcaatga
    29821 tatcactggt ctcatgggcg atgaaaaaat ggctcatgtg gtagctgaag cgagagcgca
    29881 agtggtcatc atgtttaatc cagttatggc gcgacctcaa caccctagct cgctcatatt
    29941 ccctcatttt ggatttaatc aaacttttac agtagaagag ttagctgact ttgaaatatt
    30001 gccaatcgaa gacttgatgg tggctttctt tgaacgagca ctagcgagag cggcagaagc
    30061 tggtattgca ccagaaaata tcctgttgga tccaggaatt ggctttggtc tgaccaagaa
    30121 agaaaatctg cttcttttac ggaacctgga taaactacat cagaaaggct atccaatctt
    30181 tctcggagtt tcgcgcaagc gatttgtcat caatatccta gaggagaatg gttttgaagt
    30241 caatcctgag acagagcttg gtttccgaaa tcgggacacg gcttcggctc atgtaactag
    30301 tatcgctgcg agacagggtg tagaagtggt gcgcgtgcat gacgtagcta gtcacaggat
    30361 ggcagttgaa attgcctctg ccattcgtct ggctgatgaa gcggaaaatt tagatttaaa
    30421 acaatataaa taagatgaaa gaaattgaaa acaatcagtg gattgctaac taccggacgg
    30481 atcaaccgca ttttggtttg gaacgaatgg tggaactgtt agctttgcgt ggcaatcccc
    30541 atctcaaact caaggtcctc catatcggag ggactaacgg caagggctcg actattgctt
    30601 ttttgaaaaa gatgctagaa aagctagggc tgagagttgg cgtgtttaac tcgccctatc
    30661 tcattcatta cacagaccag attagcatca atggggaatc gatctcagaa gcgaggctag
    30721 aagctctcat ggcagactat cagtctttga tggggggaga agcggtcgcc aatttacagg
    30781 gcacaaccga gtttgagatt atcacagccc tggcctatga ctactttgcc tcagagcaag
    30841 tagatgtggc catcatggaa gttggcatgg gtggactttt ggatagtacc aatgtctgtc
    30901 agcccatttt gacaggaatt acaactattg gcttggatca tgtggcccta cttggtgaca
    30961 ccttggaggc catagcagag cagaaggcag gtattatcaa acaagggatg cccttggtaa
    31021 cagggcgtat tgctccagaa gccttggctg tgattgaccg cattgcggaa gggaaagatg
    31081 cgccgagact tgcctacggg acagattatc aggttcgtca tcaagaaagt gtggtgacag
    31141 gggaagtctt tgactataca agtgctgtca gacaaggtcg cttccagact agcctgcttg
    31201 gtttgtacca aatagagaat gctgggatgg ccatagcttt acttgatact ttttgtcaag
    31261 aagatggtcg agagctagca agcaatgact ttcttggtca agccttggaa gaaacaagtt
    31321 ggccagggcg tttggaaatc gtgtcaagag atcccttgat gattttggat ggagcccata
    31381 atccccatgc tatcaaggcc ttgttggtaa ccttgcaaga acgttttgcg gattatcata
    31441 aggaaatcct cttcacttgt atcaaaacca aagccttgga ggatatgttg gacttgctgg
    31501 gagccatgcc agataccgag cttactctaa cacattttgc ggatagtcgg gcgacggatg
    31561 aaagcgtgct gaaagaggca gctaagtcta gaaatctcag ctaccaagat tggcatgatt
    31621 ttctagagca gaatttgaca gataaaaaag aagagaaaca aacagttagg attgtcacag
    31681 gttccttgta tttcttgagc caagtgaggg cctatctgat ggagaggaag aacgagaatg
    31741 gatacacaaa agattgaagc agctgtaaaa atgattatcg aggctgtagg agagaacgct
    31801 aatcgcgagg gcttgcagga aacacctgct cgtgtagccc gtatgtatca agagattttt
    31861 tcaggtcttg gtcaaacagc agaggaacat ttgtcaaaat cctttgaaat tattgacgat
    31921 aatatggtgg tagaaaagga tatctttttc cataccatgt gtgaacacca cttcttgcca
    31981 ttttatggta gagcgcacat tgcctacatt ccagatggtc gtgtggcagg cttgtctaag
    32041 ctagcccgta cggttgaagt ttattcgaaa aaaccacaaa ttcaagaacg tttgaatatc
    32101 gaagtggccg atgccttgat ggactatcta ggtgctaaag gagcctttgt tgtcattgag
    32161 gcggaacata tgtgtatgag tatgcgtggt gttagaaaac caggtactgc aaccttgacg
    32221 acagtagctc gtggtctatt tgaaacagat aaggacctcc gcgatcaagc ttatcgttta
    32281 atggggctat aaaaagaatc cgctttaagc ggatttttct agaaaggaat cattatggat
    32341 caactgcaga ttaaggattt ggaaatgttt gcctatcatg gtctttttcc tagtgagaaa
    32401 gaattggggc agaaatttgt cgtttcagcc atcctatcct atgatatgac caaggcagct
    32461 acagacttgg atttaacagc ctctgtccat tacggagaat tgtgtcagca gtggacgact
    32521 tggtttcagg aaacgagtga agatttgatt gaaacggtag cctataaact ggtggaacgt
    32581 acctttgagt cttatcctct tgtccaagaa atgaagttgg aactgaaaaa accttgggca
    32641 ccggtgcatt tgtcactaga tacttgctcg gtaaccattc atcgccgcaa gcaacgagcc
    32701 tttatcgccc taggaagcaa tatgggagat aaacaagcaa acttgaaaca agccattgag
    32761 aaaatgcgag ctcgtggcat ctatattctc aaagagtcca gtgtcttagc gacggagcct
    32821 tggggtggag tggagcagga tagctttgcc aatcaagtgg ttgaggtgga aacctggcta
    32881 ccagcacaag acttgttaga aaccttgtta gccattgagt cagagctggg acgggtgaga
    32941 gaagtgcatt ggggacctcg tttgattgat ttggacttgc tctttgtgga ggaccagatc
    33001 ctttatacag acgacctcat attgcctcat ccttacatag cggaacgcct ttttgtcctt
    33061 gagtccttac aggaaattgc gcctcatttt atccatccga tattaaaaca accgatccgc
    33121 aacttgtatg atgctttgaa aaaatagaaa aactctagtt ttcagttact tgcaactgaa
    33181 ggctagagtt tttaaaatag gtcattttct tctgggagga ggatagtttc tctaccgtcc
    33241 atgtctaaaa ccagtactct tgggggataa cgagggtcga aagggtggtt aaagtcaaaa
    33301 tcaatggctg tagggaggtg ttgacttgaa aagtggaagg taatctttcc ttggttatta
    33361 agcaattgaa actcgagttc ttcttccaat tcaaagacat tttttaagaa atgatcgatg
    33421 atataccaaa aagagtcaat gatgtcatcg ggcaagctgg taacaatgcc aaaactagca
    33481 gaccgcatgt gggtattggt aaaagccata tctctgtccc ctttcttttc ccttatcata
    33541 cagcaaatag gattaaaaat caagaaaagg tgattttttg aaaaggattt taactacaag
    33601 gaaaaagaag gaaaaaaatt cccaaaaatc taccgaagtt aataggtaaa ttcccaaatt
    33661 aacttgatta tataactttc agttactttg agaagttacc gaaaaatatt tttcatatct
    33721 attgactttt aggggtgaaa tttggtatga tagtaggcgg tattgtttac cccatttgaa
    33781 aggccccgga accttccaaa tacttttcga tgggaaggaa cacccatcac cgtaaacaaa
    33841 aatcgaacta tatataggag aaatcatgaa caaaacaaca tttatggcta aaccaggcca
    33901 agttgaacgt aaatggtacg tagttgacgc aactgatgta ccacttggac gtctttctgc
    33961 agtagttgct agcgtacttc gcggaaaaaa caaaccaaca tttacaccac acactgatac
    34021 aggtgacttc gtgattgttg tcaatgctga aaaagttaaa ttgactggta aaaaagcaac
    34081 tgataaaatc tactacactc actcaaacca cccaggtgga ttgaaacaaa tctctgcagg
    34141 tgaacttcgt tctaaaaatg cagtacgttt gattgagaaa tcagttaaag gtatgcttcc
    34201 acacaataca cttggacgcg ctcaaggtat gaagttgaaa gtatttgttg gagctgagca
    34261 cactcacgct gcacaacaac cagaagttct tgacatttca ggacttatct aaggaaagga
    34321 acaataaagt atgtcacaag cacaatatgc aggtactgga cgtcgtaaaa acgctgttgc
    34381 acgcgttcgc cttgttccag gaactggtaa aatcactgtt aacaaaaaag atgttgaaga
    34441 gtacatccca cacgctgacc ttcgtcttgt catcaaccaa ccattcgcag ttacttcaac
    34501 tgtaggttca tacgacgttt tcgttaacgt tgtaggtggt ggatacgctg gtcaatcagg
    34561 agctatccgt cacggtatcg ctcgtgccct tcttcaagta gacccagact tccgcgattc
    34621 attgaaacgc gcaggacttc ttacacgtga ctcacgtaaa gttgaacgta agaaaccagg
    34681 tcttaagaaa gctcgtaaag catcacaatt tagtaaacgt taattcgaaa gaattactat
    34741 acttatacag agcacctttc ggggtgttct ttttttatac tttcttacta aattggtgca
    34801 attgacacag ttgttgcgac tttagtcgct tacaaatgtg gctgcaacct gacaaggtca
    34861 gttgcctcaa aacgttaatc aatacgatta tatcaatgtt tcaaagcact caaaagttta
    34921 ccttatgggt gcttttttcg tgcttttttg aaaagtttac cttattttta tagtaatgtg
    34981 aaataagaat aggacaaatc gaggatagtc aaatcgaatt ctaacaatgt tttagaagta
    35041 gaggtgtact attctagttt caatctacta tattatggat aatgcaagat tccatagaat
    35101 ggggaag
//
LOCUS       DBEJNA010000025        34203 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEJNA010000025 DBEJNA010000000
VERSION     DBEJNA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.25"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(51..1240)
                     /locus_tag="ACL3JB_001307"
                     /pseudo
     CDS             complement(51..1240)
                     /locus_tag="ACL3JB_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1222..1529
                     /locus_tag="ACL3JB_001308"
                     /pseudo
     CDS             1222..1529
                     /locus_tag="ACL3JB_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1684..2007)
                     /gene="tnpB"
                     /locus_tag="ACL3JB_001309"
     CDS             complement(1684..2007)
                     /gene="tnpB"
                     /locus_tag="ACL3JB_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0686032.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELNSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1988..2173)
                     /locus_tag="ACL3JB_001310"
     CDS             complement(1988..2173)
                     /locus_tag="ACL3JB_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686033.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2477..4039)
                     /gene="guaA"
                     /locus_tag="ACL3JB_001311"
     CDS             complement(2477..4039)
                     /gene="guaA"
                     /locus_tag="ACL3JB_001311"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0686034.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKADWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4181..4879
                     /locus_tag="ACL3JB_001312"
     CDS             4181..4879
                     /locus_tag="ACL3JB_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0686035.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4922..5818)
                     /locus_tag="ACL3JB_001313"
     CDS             complement(4922..5818)
                     /locus_tag="ACL3JB_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0686036.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5827..6762)
                     /locus_tag="ACL3JB_001314"
     CDS             complement(5827..6762)
                     /locus_tag="ACL3JB_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0686037.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6759..7484)
                     /locus_tag="ACL3JB_001315"
     CDS             complement(6759..7484)
                     /locus_tag="ACL3JB_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0686038.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7568..8203)
                     /locus_tag="ACL3JB_001316"
     CDS             complement(7568..8203)
                     /locus_tag="ACL3JB_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0686039.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNSLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8205..9032)
                     /locus_tag="ACL3JB_001317"
     CDS             complement(8205..9032)
                     /locus_tag="ACL3JB_001317"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0686040.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9054..9389)
                     /locus_tag="ACL3JB_001318"
     CDS             complement(9054..9389)
                     /locus_tag="ACL3JB_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR0686041.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9390..9980)
                     /locus_tag="ACL3JB_001319"
     CDS             complement(9390..9980)
                     /locus_tag="ACL3JB_001319"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0686042.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQALLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLELTEEQKALY
                     HKMIDWGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(9996..10118)
                     /locus_tag="ACL3JB_001320"
     CDS             complement(9996..10118)
                     /locus_tag="ACL3JB_001320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686043.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            10631..11242
                     /gene="def"
                     /locus_tag="ACL3JB_001321"
     CDS             10631..11242
                     /gene="def"
                     /locus_tag="ACL3JB_001321"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0686044.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11287..12015
                     /gene="rlmB"
                     /locus_tag="ACL3JB_001322"
     CDS             11287..12015
                     /gene="rlmB"
                     /locus_tag="ACL3JB_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0686045.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12054..12965)
                     /gene="trxB"
                     /locus_tag="ACL3JB_001323"
     CDS             complement(12054..12965)
                     /gene="trxB"
                     /locus_tag="ACL3JB_001323"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0686046.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13031..13255)
                     /locus_tag="ACL3JB_001324"
     CDS             complement(13031..13255)
                     /locus_tag="ACL3JB_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0686047.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13333..14076)
                     /locus_tag="ACL3JB_001325"
     CDS             complement(13333..14076)
                     /locus_tag="ACL3JB_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0686048.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14076..14876)
                     /locus_tag="ACL3JB_001326"
     CDS             complement(14076..14876)
                     /locus_tag="ACL3JB_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0686049.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15034..15390)
                     /locus_tag="ACL3JB_001327"
     CDS             complement(15034..15390)
                     /locus_tag="ACL3JB_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0686050.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15403..15915)
                     /locus_tag="ACL3JB_001328"
     CDS             complement(15403..15915)
                     /locus_tag="ACL3JB_001328"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0686051.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15915..16409)
                     /locus_tag="ACL3JB_001329"
     CDS             complement(15915..16409)
                     /locus_tag="ACL3JB_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0686052.1"
                     /translation="MEIRLAFPNEVGAIMQVIEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16544..16990
                     /locus_tag="ACL3JB_001330"
     CDS             16544..16990
                     /locus_tag="ACL3JB_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0686053.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16987..17634
                     /locus_tag="ACL3JB_001331"
     CDS             16987..17634
                     /locus_tag="ACL3JB_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0686054.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17655..18236)
                     /gene="pdxT"
                     /locus_tag="ACL3JB_001332"
     CDS             complement(17655..18236)
                     /gene="pdxT"
                     /locus_tag="ACL3JB_001332"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0686055.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18237..19112)
                     /gene="pdxS"
                     /locus_tag="ACL3JB_001333"
     CDS             complement(18237..19112)
                     /gene="pdxS"
                     /locus_tag="ACL3JB_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0686056.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19264..20643)
                     /gene="nox"
                     /locus_tag="ACL3JB_001334"
     CDS             complement(19264..20643)
                     /gene="nox"
                     /locus_tag="ACL3JB_001334"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0686057.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20937..21860
                     /locus_tag="ACL3JB_001335"
     CDS             20937..21860
                     /locus_tag="ACL3JB_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0686058.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21920..22525
                     /locus_tag="ACL3JB_001336"
     CDS             21920..22525
                     /locus_tag="ACL3JB_001336"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0686059.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22544..23788
                     /locus_tag="ACL3JB_001337"
     CDS             22544..23788
                     /locus_tag="ACL3JB_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0686060.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRHFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23905..24162)
                     /locus_tag="ACL3JB_001338"
     CDS             complement(23905..24162)
                     /locus_tag="ACL3JB_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0686061.1"
                     /translation="MDPKKIARINELAKKKKTEGLTLEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24204..26240)
                     /gene="glyS"
                     /locus_tag="ACL3JB_001339"
     CDS             complement(24204..26240)
                     /gene="glyS"
                     /locus_tag="ACL3JB_001339"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0686062.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGGATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26452..27369)
                     /gene="glyQ"
                     /locus_tag="ACL3JB_001340"
     CDS             complement(26452..27369)
                     /gene="glyQ"
                     /locus_tag="ACL3JB_001340"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0686063.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27912..28489)
                     /locus_tag="ACL3JB_001341"
                     /pseudo
     CDS             complement(27912..28489)
                     /locus_tag="ACL3JB_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(28762..29604)
                     /locus_tag="ACL3JB_001342"
     CDS             complement(28762..29604)
                     /locus_tag="ACL3JB_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0686064.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29718..31109)
                     /gene="pgdA"
                     /locus_tag="ACL3JB_001343"
     CDS             complement(29718..31109)
                     /gene="pgdA"
                     /locus_tag="ACL3JB_001343"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0686065.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIELLKKEKDDQLSEGNQKEYFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31347..31715)
                     /locus_tag="ACL3JB_001344"
                     /pseudo
     CDS             complement(31347..31715)
                     /locus_tag="ACL3JB_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31936..32913
                     /locus_tag="ACL3JB_001345"
     CDS             31936..32913
                     /locus_tag="ACL3JB_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0686066.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQIPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32910..33992
                     /locus_tag="ACL3JB_001346"
     CDS             32910..33992
                     /locus_tag="ACL3JB_001346"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0686067.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34056..>34203)
                     /locus_tag="ACL3JB_001347"
     CDS             complement(34056..>34203)
                     /locus_tag="ACL3JB_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0686068.1"
                     /translation="RKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIVNQRWTRML
                     FESR"
BASE COUNT        10109 a         7659 c         6192 g        10243 t
ORIGIN      
        1 aaaatctcca gactagagaa ctcacggata gttcctaatc tggagatttc ttatttgcac
       61 ttttcttgta caactttagt ccatggtaaa taagcctcta aaacctcttt gtttacgaga
      121 gtttcctcgt ttggaagaca ttctagaaga taggatagat atttctcact atttagttga
      181 tgacgtttag ctgtttccaa caaactcata ataatagctc ttgctttagc tccttcaaaa
      241 ctttgagaaa acaaccaccc tcgctttttt aaactgagct taggctaaaa gagtccagtg
      301 gactctttta ctccgtccca taaccaatga tttaatggcg tgttcagcta gattattgga
      361 aaggaccaga tgtccgtctt ttaaaatggt cttaaaggtt tcttcatact tgaggctgta
      421 ttcaattgcc cttcctggtt ttgaacctgc taaaactgac tgacggcggc accaagcaaa
      481 gaagtcttcc attaagggct ggacgtttct gtagtcgttc atcagctggc aaagcctccc
      541 agtctctttc caaggcaaat aactggtcac gataggctaa acctttagct cctaaggatg
      601 atttatctgc ttgcttgggg gtcgcttcaa aaaatttcct tctcacatgc gcccaacatc
      661 caacaagttc agcttcttcc agttgacgat aagcttctag cggttcgcag tttaccaagc
      721 ttagcgtcgc cttgctccta aaccttagac tgctatcgca taggcagaac tagaggacta
      781 aagttctaag ttactgccgc aacatatcac aatgcatata gccagaataa tttcctagga
      841 attcttgcac taccgaacca ctccgacgct gatcatggtg gtacagcgta atcccttgtt
      901 tctcagcttt cccagacaaa aaagtccaat agtaagtcag ctgactatca ctttctaaga
      961 cccgataaga ggtttcatct gcatgaagaa gagcttgttc taacaacttt tctcgtaaaa
     1021 ggttataaag gggctccaaa tagtattgac tcgtcttgat atgccaatta gagatttcct
     1081 tacgtgtgat tggtaaaccc atcctagccc aatcttcttc ttggcgataa ttgggtacct
     1141 tcagattaaa cttctgatgg atggtgtgag cgataataga agctgagcca aggctatgcg
     1201 ccaaaggggc tttaggaata ggagctttca caagcttatc cagatgatta tcttttactc
     1261 gttatgaaca atgctatatg gcataaatca agtaccttaa agattccgac taatattggc
     1321 tttgcattta ttcctccata cacaccagag atgaacccat tgaacaagtg tggaaagaga
     1381 ttcgtaaacg tggatttaag aataaagcct ttcaaacttt ggaagatgtc atgaatcaac
     1441 ttcaagatgt tatacaagga ctggagaagg aggtgataaa gtccatcgtt aatcggagat
     1501 ggactagaat gctttttgaa agcagatgag tataaaaaga aagtcctcat ttcaatagaa
     1561 atcacgactt tctgatggat ttatagtaaa atgaaataat aacaggacaa atcgatcagg
     1621 acagtcaaat cgatttctaa caatgtttta gaagcaaagg tgtactattc tagtttcaat
     1681 ctactatatt tttggagtga tagaaaagcc tttcatcagc caatctactt gttcaggtgc
     1741 gagagctttg acatcctttt ctgtactggg ccaagtcagt ctgccgttct caaagcgttt
     1801 atataatagc caaaatcctt gaccatccca gtaaaggact ttaaagcggt ctttacgtcc
     1861 accacaaaag agaaaaactt gacctgagaa agaattcaat tcaaagtggg ttttaaccag
     1921 ataagccagt gaatcgattc cttgtctcat acccgttttc ccacatacga gatagacctg
     1981 ccctaggcta gatagatgaa ttgtcataga gcaacacctt atccaaaagc tgttctatca
     2041 tttcgagatt gagagattga aaaaaactta cttcaagctt gccaatacga attttaagca
     2101 gaatatcatt tctcttttta gaatcaaaac gacgagattg tggaatctct acaggaacaa
     2161 taggttgtgg cattaaaata tcctccaata gttttacttt actaatagta tacaggagga
     2221 gctccatgaa tgatagatac cttgttatga cgcgcttacc atattagaaa gttggctctc
     2281 taattaaatt aattctcatt atatatatca aaaaaccgca gcttgaaaac tacggtctaa
     2341 ttttttgtcc aaatgtaaac cacttggaac tattattcaa tttattcttt ttagcaaatg
     2401 ttcccgtttt aatcccagtt acagttttta atcctctgta accgttgatt ttacaaagct
     2461 tttaattttt ttgcgattat tcccactcaa ctgttgcagg tggtttactt gtaatatcgt
     2521 agacgatacg gttaacatga tccacttcat ttacgatacg tactgagatt ttttgaagta
     2581 cttcccatgg aattttggca aaatcagcag tcataccatc gatagaagtg atagcacgga
     2641 ttgcaatcgt gtagtcatac gtacgaccgt cacccataac accgactgag cgaacgcctg
     2701 tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc agctttagcg atttcttcac
     2761 gaagaatagc gtctgattca cgaacggttt caagtttctc ttcagtgatt tcacccatga
     2821 cacggatagc aagtcctggt cctgggaatg gttggcgcca tacgatgtgg tctggcatac
     2881 caagctctgt accaagagca cgaacttcat ccttgtaaag agtattgagt ggttcaatca
     2941 gttcaaactg catatcttct ggaagaccac ccacgttgtg gtgtgacttg atagtttgag
     3001 ctgtatccgt accagactcg ataacatctg tatataaagt accttgagca aggaatttca
     3061 catctttgag cttgcttgct tcgtcatcga atacatagac aaactcgtta ccgatgattt
     3121 tacgtttttg ttcaggatca gaaacgccag caagtttgtc aaggaaacgt ttagcagcgt
     3181 ctgctttgac gatattcaaa ccaaacttac caccgagcat gtccataact tgatcagctt
     3241 cgcctttacg aagaagaccg tggtctacga agatacagat caattgatcg ccaatcgctt
     3301 tttggagaag aaccccaacg acagatgagt caacaccacc tgatagacca agaaggacac
     3361 gtttatcacc gacggtttca cgaatttttt tgatctgcat atcaatgaaa ttatccattg
     3421 accagtcagc tttagcctta caaatgttaa gggcaaagtt acgaaggata tcatttccgt
     3481 atacagaatg acgaacttct gggtggaatt ggataccgta aatgtgttta tctgggtttt
     3541 cgatggctgc gtatgggcag tcagctgatg tacctgtacg aacaaagtca gcaggaatct
     3601 cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc atcaggtgtt gattcaaaaa
     3661 gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc acgatttcca gcatcacctg
     3721 caggaacaac ttttcctcca agtttatggg tcaataactg cataccataa cagattccca
     3781 aaattggaat tcctagttcg aagatttctg ggtcaatgtc aaatgaacca tcttcatata
     3841 cagaatttgg accacctgat agaataattc ctacaggatt gacttcacga acttcagcag
     3901 ctgaaatttt atggcttttt agttctgaaa aaacaccaat ctcacggata cggcgtgaaa
     3961 tcagctggtt gtactggcta ccatagtcca atacgatgat tttttctaca tcttgcaaat
     4021 cagttgaaat gttgctcatc tttttccttt ctcaaaagaa atatcttttc tcaatattct
     4081 atcacaaata agggcgaatt accaactaaa caaggcgaag tttgactttt tctagtttat
     4141 tggggtacaa tagagaaaag atagaaatga agtgaaaaat atgctacctg cttatatgaa
     4201 aatccatgat cagataaaaa aggatattga cgagcaccgt tgggctattg gtgagaggct
     4261 tcccagtgaa agagatttag ctgagcagtt tgcggtcagt cgcatgaccc tccgccaagc
     4321 cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt gtaggaagcg gcacctttgt
     4381 ttccagtact cgagtacaag aaaagatgcg agggacaacc agttttactg aaattgtcaa
     4441 atcccaaggt aaagttccct ctagccagct catttcctac aaaaaaacca ttcccaatga
     4501 gcaagaagtt gccaagctag gaatttttcc aacggacaat attatccgaa tggagcgggt
     4561 ccgctatgcc gaccaagttc ccctagttta tgaagttgct tctattcctg aaaaattcat
     4621 taaggacttt aaaaaagaag aaatcaccag tcatttcttc caaaccttgc aaaaatatgg
     4681 ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc cttgctaaag aaaagattgc
     4741 ccactatttg gaagttgaaa aaggacatgc tattcttgga ttgacacagg tttcctacct
     4801 agaagatggt actgcttttg aatacgtaaa aagtcaatat gtaggcgaac gctttgaatt
     4861 ttatcttgaa aataattaga ttaccacgca aaaactctct gtcacagaca aagagtcttt
     4921 tttatttttc taagaataaa tctttcaaag aaatcaaagt tacagcaaac aatatcattg
     4981 ccataccaat aaaatcaatg ggataaaatt gttcattcat tattaagaag gcaaagaaaa
     5041 ccgccgatat tggctcaatt gaagccaaca agcttgactt gaccggtcct atcagactgg
     5101 ctcctttaag gaaagctgta taggcaaaga cagtcccgat aaggataatg cctgcaaacg
     5161 caaggagaaa atcaagacta gtcgggatat cggcctgtag aacccctgta aaaggaaggg
     5221 cgaccaaacc tgctatgacc attcccacac caatgaccaa gctgctcccc cactttttaa
     5281 tcaaggctat gggtaaaatg atatacagag cataagtcaa ggcagaaaag agaccccaga
     5341 acaggccagc aggtgtcatg gataactggt ccaactgccc atgtgttgcg atcaggaagg
     5401 ttcctccgat ggcgaatatg atggaaacta tctctcccag tgtcggtgcc accctatcct
     5461 tgatacagct ataaattaaa attccgacag gacaaacata ctgaagcacc gtcgctgttc
     5521 ccgcattggt ctcctgaata gcagacagat aggcgaattg gttgagaaaa agaccaatca
     5581 gagcaaaaat aagaagagac agcaaactct ttctatcctt taaaaagacc agtattttat
     5641 cctttgcagt agcataagcc aagagcatga gaattccacc agcgattaaa agacgcaagt
     5701 tggttaagac cagagccgaa attccgtgtg ccatcaggta ttggccactc gttcctgaca
     5761 acccccaagc aataccagcc acaactgtta gtaaagtccc ttttaaacta tttgacatgt
     5821 ctctccttac tcttctttgc gaatcaagtt catcacttga ttgcggtcta atatccattg
     5881 agctctctcg tccttttcat aggtacgatt cgataggaaa atagtggctt cttgcttctg
     5941 acgattccac atgataaagg tacctgtata gcccgtatgg tctagccaat ctccttccaa
     6001 attccatgct aaagaacgtt ccttgtcatc caaaggagaa aaattttgat ttaagtctct
     6061 tgcaaaatca tctgctaaat agtgttctaa aaagatttgt aaatccttta tagtcgaaaa
     6121 taaaccagca ctcccagcat gtctacccag gagacgagcc ttgggatcat gcactatgcc
     6181 tgcctctaca cctctaactg ttggaacagc aagctcaact ggcccaaact tggtttccgt
     6241 cattccccaa ggtttccaga cttgatcctt taaaatcaca tccaaatctt gattaaaaat
     6301 tctttccaaa ataaagccca acagcaaaaa atggacatcc gaataaagaa aggctggctg
     6361 acttcgtctg ttgagatgaa acatcgcttc ctttaattca ggggctgtta aaagatcacg
     6421 attaggaata aaaggatcaa ggtctgttgc atgagtcaag agctggcgaa tagtgatgtc
     6481 tggataatca ctctcaggta aaaaatctat taccagtcta tcaatatcta attgacctat
     6541 ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc ttgctgacac tagctaggtc
     6601 ataaactagt cctgcctcag tctgcaagcc atgctctggg tcactctggc ctaaatagaa
     6661 ctctgtccat tgattgtcct taaaatacgc aaaagaggct ccgggataaa ttcctgcctc
     6721 gatttgttct tctatttttt taataatctt ggtccacttc atacttcttc aaaccacaat
     6781 tcaacattat ttctatcttt accaaggaag aatttttcag acttaggaat aaaatattca
     6841 gtagactcaa acttctggcg aagacttgct atgtctaatt cattgaccaa gaacttgagc
     6901 atagataagt cccaggtaac cgtattgtcc acagtcaaat cctgcccctg agctggaata
     6961 aaatcaaggg atgccccaat ttcagatgat tccaagaaac tttcgatatc agttgggaga
     7021 tgtaattcca tagaaatctc aaatttactt aaagaaattg atgccaaatc tgtttgaaat
     7081 tcaggctttt ctcctacttc tactagactt gctctgtcat cttccgcatg aatcaaaatc
     7141 aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat tttgaccttt atataatcga
     7201 tgaatcgaat ctgttttaga taagattcct tcaatttcta agggattttc caccttgaca
     7261 atcaatctag ctagtttttt tcttccctct accttacgag tacgcatact gggagcttct
     7321 tctaaaacca gcttttcaag acccgtttgg tcacctagtg acagaaaggc cgattcttct
     7381 aacaaggcct tcattccaag ggtttcaata taaaatgttt catttaattt tctattatta
     7441 gcttttaaag taggaataat ccgtacaatc tgatttacat tcataaattc ctccgtcact
     7501 ttttatttta aaggatttta gaatttttta caagatatta tgctcaaatt taacattatt
     7561 tagctattta gtaaagatag tctttcaagg cttttgacaa agcctgataa ccagcaatac
     7621 tgaggtgcag tccatcagtt gtatattctt ttttgagttg gcctgcttgg tctgtcaaac
     7681 aatcaaatac tggcacaaat tccacctgca tataggcaga tgcaagctct tgataggctt
     7741 gattccaatt ctgaattttt tcattcgagc ggatatagac tgcctgctgg tacttctctc
     7801 cctcattgac aggcaaaatg gaaagcaatt taatctctgt caatggataa tcgcgagcaa
     7861 cggattgaat gatagcttcg agactattga gagcctcatt cacaggaaca tcctttccga
     7921 tatcatttgt cccaatcaga agaaaaattt tatctactgc tccaccatat agatgagcat
     7981 caaggttctc tagtaacagt cctgtctgat agccacgaat tcctcgattg acaatcgtct
     8041 ttgaagtccc aaatagctcc tgtagaggat aatactcgac aatggaatcc ccaataaaaa
     8101 gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg atatttggtt tgaatttttt
     8161 cttgttcctt taggagccaa ttttctaata actgtactgc cacttcattc tcctttttct
     8221 aaccagtttt ccaagacttg ataaactcct ccttggctgt tggctggtgc tagagcagtc
     8281 gccacagctt tggctttctc atcagcattt tccatcgcat aggcaattcc agccatttca
     8341 agcatttcaa catcattttc actatcacca aaagccatga tttcttggga tttcaagtcc
     8401 cagcgcttga gtaattcctc caagccccat gctttatgaa tcccagcttg gaggatatca
     8461 atgcaaccat agccactgga tacagctcgg acacggccat caaagagagc attgatttct
     8521 tccaaaaccg aactcaaacg ttcctcacca acaaccatgc tcatcttgag cacaccacca
     8581 aagaggtcag atgttaattc atccacaaat tgcatccgtt ggtagaattt ttcaatcatt
     8641 tctggagtca taaaactttc aagatctgta aaaatcgtac cttccttgac aaaatcaccc
     8701 ttcatccccg ttacaacaaa ctggtcctga cacgctcgac ccttgaaatg agccaaagcc
     8761 ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca attcattgtt ttcaaaaata
     8821 cgagcgccat tagcaacaac cagaaccact cgatccacca agggactcag tagttgtctc
     8881 atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa tgcccctttg atccaactga
     8941 tctaaaatct tttccaatcg tgggagatca agctgacctc tagcatccag caaggtccca
     9001 tccatatctg tcgcaattac cttaatcatc atttactttc ctctggattc aagctaatac
     9061 cacttcaatc ccacatgttc attcatttct ttataggctg tatcaattcg ttccttagtc
     9121 gcttcatcta actggtcacg atgactgcca tcctctataa aatcttccaa aatataagtt
     9181 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
     9241 caagtaggat gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg
     9301 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
     9361 atccgttgat tggaaatgaa gttccccatt taatagataa tgagtttctt atctccatct
     9421 ttttcaaccg tttcagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct
     9481 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttagttc caatcgatac
     9541 tcaacaccca tctgaagcat gataatggtg atatctgctt ccttctctgc ccgttcaatt
     9601 tcaaccttca tcttatcttc gtttaaatct gaaagataac gattatagtc ttcctgagaa
     9661 atatactgct caattccatt gaaaccatag gaataggcta acaatgcaac cttgatacca
     9721 ttcacttcct taatgaccag cagagcctga tcacgtggtt cgtgcgtata aactccgatt
     9781 ggagtgattc cagctttctc aataatatcg gccgttgaaa taactccctc aatttgcgaa
     9841 tccaaaatat gattatgagc taaatccagc acatgataac ctgcctcctt aatagcatcc
     9901 ataacttcag caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
     9961 gttccttcaa aatcaccaat agctaaatct gctgcttagt ccccttgctt gagccaagga
    10021 gtcacatact caaaattttc atgaaagtca taggtaccgt cttctttttt agctgaaaag
    10081 aaaagtccat cgtggtagag caaatccccg tgggccataa ttctggcagt tttttcctct
    10141 tcctactcct gagacttttg cttagtcccc tcttgagaaa tagtatctcg tttttgacta
    10201 gtcaagggat tccttggaag ctttcaaaca acaagaccaa gcccattgat aaatcaactg
    10261 ctagcaagag tatcgccaca aatcccttat tgctccactt gcgataactc ctaaaaagtt
    10321 taccaagccc ttcataaaac gaaaagctaa accaccctga tttcgatttt gtcttctttg
    10381 tatcttcatt ctccctactt tcttatgcaa gccttttctt tttattatat cacagataag
    10441 tatttctttc acaattgaat tgaacttccc atctattttc tataaatcct aaatgccata
    10501 atgctttcaa ttcttgtcat tttgtgatat catgtagagg aaatgaacta atccacagtg
    10561 gcttattcca agtataccac ttgggctttg gcagtagcta actgcactaa acataatata
    10621 aggagagaaa atgtctgcaa tagaacgtat tacaaaagct gctcacttaa ttgatatgaa
    10681 cgatattatc cgtgaaggga atcctactct acgcgcgatt gctgaggaag tcactttccc
    10741 cctatctgac caggaaatca tcctaggcga aaagatgatg caattcctta aacattccca
    10801 agatcctgtc atggctgaaa aaatgggact ccgcggtggt gttggactgg ctgctcccca
    10861 gttagatatc tcaaaacgca ttatcgctgt tttggtacct aatattgttg aagaaggcga
    10921 aactccacag gaagcctacg atttggaagc cattatgtac aatccaaaaa tcgtctctca
    10981 ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc ctgtctgttg accgtaacgt
    11041 gcctggctat gttgttcgcc atgcccgcgt tactgttgac tactttgaca aagatggaga
    11101 aaaacaccgt atcaaactca aaggctacaa ctccattgtt gttcagcatg aaattgacca
    11161 cattaacggt atcatgtttt acgatcgcat caatgaaaaa gacccatttg cagttaaaga
    11221 tggtttactg attcttgaat aaagaaaatc ccgttgcaag acggggtttt gtgttataat
    11281 agaggcatga aaacaaatga tattgtctat ggtgtccacg ccgttaccga agctctcctt
    11341 gcaaatacag gaaacaaact ctacctccaa gaagatctcc gaggtaagaa tgttgagaaa
    11401 gtcaaggaac tagctacaga aaagaaggtg tccatttctt ggacatcaaa aaaatctctc
    11461 tctgagatga ctgaaggtgc tgttcatcaa ggttttgttc tacgagtgtc tgaatttgcc
    11521 tatagcgagc tagattacat ccttgcaaaa acacgccaag aagaaaatcc acttctattg
    11581 attctagatg gtctaaccga tccccataat ctgggttcta tcttgcgaac agccgatgcg
    11641 accaatgttt caggtgtcat cattcccaag caccgtgctg tcggagtaac tcctgtcgtt
    11701 gccaaaacag ccacaggtgc tattgaacac gttccaattg cccgagtgac aaacctcagt
    11761 caaaccttag ataaactcaa ggatgaaggc ttctggacct ttggaacgga tatgaacggt
    11821 actccttgcc acaagtggaa tacaaaaggg aaaatcgccc tcatcattgg aaatgaagga
    11881 aaaggtatct ctagcaacat caaaaaacaa gtcgatgaga tgattaccat tccgatgaat
    11941 ggacatgttc aaagccttaa tgccagtgtt gctgcggcca ttctcatgta cgaagttttc
    12001 cgaaatagac tataaaaaag tttccagtca tctgattgga aactttttta tgattaacta
    12061 tgttctgtga taaacttgta ggcttcttga ccagcgatag ctccatctcc aactgctgtt
    12121 gttacttggc gaaggtcttt caagcgaaca tctccaactg caaagatacc gtcgactgca
    12181 gtcttcatgt ggctatctgt cacaatccag cctgcctgat cttggatatt caattcttta
    12241 acaaaatcgc taagagggtc caaaccaaca tagataaaga caccaccgaa ggcttgttct
    12301 gtcacttgac ctgttttcac attttcaaat acgactgatt ctactcggtt ttcacccttg
    12361 atttccctta ctacagaatc ccagataaag ctgatttttt cattcgcaaa ggcgcgatct
    12421 tgtaaaacct tttgggcacg aagttggtca cgacggtgaa caatggtaac agtcttagca
    12481 aaacgagtca agaagagggc ttcttcaaca gctgaatctc caccaccaac taccaataaa
    12541 tcttggtcac ggaagaaagc accatcacac acagcacagt aagaaacacc acgactgttc
    12601 agttcttctt ctccaggcac tcccaaagga cggtgtttag aaccagttgc tacgataact
    12661 gtacgtgttt catatgtttg gtcatcagtc atcactttct taaaatcacc atggtcttcg
    12721 acattttcaa cataaccata aatgtgctca acaccaagat tttcaagtgg ttcaaacatc
    12781 ttttcagcca attcaggtcc actaatatta gcgtatcctg ggtaattttc gatatcagat
    12841 gtattattca tctgaccacc tggcagacca ccttcaatca aagctacttt tagattgctt
    12901 cgagcagcat acaaggccgc agtcatccct gcaggtccag caccgataat aatagtatcg
    12961 tacatataga ttccttcttt cttgttgtaa ctatctttat tctaactctt tcttgtcaat
    13021 cacgcaagga ttatgccttg aaaacaagaa ttaaactcat aaccgcaaag gataatactg
    13081 ggacaaccaa gactccaatc ataatcatat catagagatg ggcttggcga gccttggctg
    13141 tcttatcaac tcccgacatg gctctcagac caatccaaat ccctaaaaaa atcagaacaa
    13201 ggatggtggt caatatcaaa ctctcgaaat ataaagaaaa tagttgcagt agcatgattt
    13261 ctctcatttc tatctttttt aaagagtaaa ctcagctagt ccaactaact gagttttcct
    13321 ttatctatta tatcaaatat aagtccgttt gtaactagcg aagaattctt ttgtccgctc
    13381 ttctttaggg gtgtggataa tctcatccgg agttccagac tcgatgattt tccccttatc
    13441 taagaagaga atcttatccg caacttgggc tacaaaggac atgtcatgac tgaccaaaat
    13501 catggtctga cctgacttag cagcatctgc aatagacttt tctacttcac cgaccaattc
    13561 tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc
    13621 acgcgctagg gcaacccgtt gcttctgtcc acctgataaa tggcgaggat aatggttttc
    13681 acggtccgaa agcccaacct tagccaactc ttccttggca atcttagtcg cttcttggtc
    13741 agataatttc ttgacaacaa ccaagccttc tttcacatta tcaagtgctg ttcggcgttc
    13801 aaacaaatta aactgttgga aaaccataga caacttacgg cgtagggcaa ggatttcttc
    13861 ttgagtgatt ttagaaaaat caactgaaaa accatcaatc tgaatagagc cactgtcagg
    13921 tgtttcaaga taattgagac tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat
    13981 caaggctaca acttcccctt tttgaatatc caagtccaga tgatccaaga cagtctgtcc
    14041 tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac gaaggtctcc tttcacatct
    14101 gtttgcactg tatcaggtgc agaaatagcc atttttctct cgatgaaacg accgaggctt
    14161 tcaattccga tattgactac ccaataaaca agggcaacgg agatgaagcg ttcaaaatag
    14221 cgataatcag ctccacctag aatctgagct tgggcaaaga cttccacaac acccgcacta
    14281 aaagctagag atgttccctt ggtcaaaccg atgagggaat taatcaaggt tggagtagct
    14341 accaccgctg cattaggaat aatcactcgt cgataaactt gcgctcgggt catacccaga
    14401 ctgcgtgccg cctcaatctc accaggatta actgagagaa tggctgcacg aatggtttca
    14461 ctagcataag ctgcctcatt aaaggcaaaa gcgacaatcg caaaagctgc agctggaatc
    14521 gcattgatat tgagaccagt tccccattgc tgattgaggg ctttcaaagc caaagggatt
    14581 ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag
    14641 aaggcctgca agggatataa aatcttgaca cgattgatct tcacaatggc aaaaagaagc
    14701 gccaaaacca agccaaaaag ggcaccacca attgtcaaca taattgttgt tggaagttgt
    14761 tggacaattc tagggattcc atcaaagacc gaacgtaggc taaacagctt gccatccgga
    14821 atcaattgca tcaagttttg gtaccaatct gatgctaaaa tcgttgtaac attcataaaa
    14881 acatcctctt ctgataatga ttcattctac catgcttctg ccgtcaatga aattatttgc
    14941 tacggtcaga tacagacttt gtctacctac tagtttatca tactttgaaa cagggaagtt
    15001 atatatttta tctatcaaag agatagataa aaactatttc agtcccagtt cttcataaga
    15061 ttttcgataa ccgatttgct taacagttcc attttctact aaaatgggcc gttttaacaa
    15121 cataccgtca cttgctagca actcagccgc ttcttggttt gacaaacttc ctaccttatc
    15181 ttttagccct aattcacggt atttgatacc actggtgttg aaaaattgct tcaattcaaa
    15241 tcctgaggtt tctagccaat tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg
    15301 gacggcttta tagtccacac ctaattgatt taattcttgt tttgcttttt tacaagttga
    15361 acatttgggg tattcgataa attctaacat gtgcttctcc ttctatttgt ttatatcttt
    15421 aaaatctacg ccttcatgct ccaagagcca agctttcttt tccactcctg cagcatagcc
    15481 tgtcagacgc ttgcctgctc ccaacacacg atgacaaggt actaggatag accaaggatt
    15541 gcgtcccact gctccaccaa ttgcttgagc agaagccact tgcaggtctt gagcaatttg
    15601 tccataggtc actgtctgac cataaggaat gccctgtaaa tagtcccaaa ctctcttttc
    15661 aaaattcgtt ccgattggcg ccaagagcaa gttggataaa tcctgaggct tgcctttaaa
    15721 gtaatcatct aagcaagcaa taactgggtc taaaatagga tgactaacaa cttcttctat
    15781 cgtttcatct cctagtcccc tctcaaaatg cttctgctcc tgaacccaaa ttccatacaa
    15841 ataatggtca tcagctacaa gtgatagaat accaattggt gaggagtaga ggatttttac
    15901 atacttcttt tgcattattt ctttaatttt tgataggcca agcgttcgcc atctactggc
    15961 accttaccaa cttgtttaaa accaagtttt tcaaaaatat gttgcataac cttgttttca
    16021 gcatgcgtat ctgagcgaaa atcaagataa tcaaaacctt caatcaagcc ctctaagaag
    16081 gtttgagcaa ctccttttcc ctgcacatct gctgccacag caatacggtg aaagactaga
    16141 tactctgact ctccagcttg ccagtttccc tcataaatag cttcataggc ctcctctgga
    16201 ctcttggtca cagcagcata ggctagcagt tctccctctt ccaaggctac gtaggcttgc
    16261 cctgagatga tatcatcgat aataacatct gcatttggat agccattttg ccactggtca
    16321 ctaccagcat ctgctaaaca ttttttggca tcctctatca cctgcatgat ggcacctact
    16381 tcatttggaa aagctaaacg aatttccatc ttttttcctc atttctgact agtttctccc
    16441 atcatagcat aatttaagtc tttctacaag cagttaaaac ttgactttgt atttttgtta
    16501 ttttataatc tagttatcaa aactatataa aaaggagttg aaaatgaaaa ctaccttttc
    16561 ctacccaaaa tgggcagaaa ttccaaacat taacctctat ctggaccagg ttttgctcta
    16621 tgtcaatcag gtctgcgccc ctatctctcc taataaagac aaaggcctaa cagcatctat
    16681 ggtcaacaat tatgtgaaaa atggttacct gacaaagcct gacaaaaaaa aataccaacg
    16741 ccaacagatt gcccgtttga ttgctatcac aaccctcaag tctgtatttt ctattcaaga
    16801 aatagcccag acacttaata ctctacaaac tcaagcaagt tcagaccaac tctacgatgc
    16861 ttttgtggac tacatgaacc aaggaattga cccagctaac cctattatcc aaaccagctg
    16921 ccaaaccgtt aaactctatc atcaaactct agacttaatc gatcatactc aagaggaggt
    16981 aatccaatga acactagtct taaactcagc aaacaactca gttttggaga ggagattgct
    17041 aatagcgtga cccatgctgt gggtgcagtc atcatgctta tcttgctgcc tatttcatcc
    17101 atctatagtt atgaagcaca cggattttta tcctctatcg gcgtttccat tttcgtcatc
    17161 agtctctttc tcatgttcct atcatccacc atttatcact ctatggccta tggttcgacc
    17221 cacaaatatg ttttgcgaat cattgaccat tctatgattt acgttgccat tgccggctca
    17281 tacacgcccg ttgtcttgac cttgatgaat aactggtttg gctatctgat tattgtcatc
    17341 caatggggaa cgaccatctt tggtattctc tataaaatct ttgctaaaaa ggtcaatgag
    17401 aaatttagcc ttgctcttta cctgattatg ggctggttgg ttctggctat cattcctgcc
    17461 attatcagtc aaacgacacc cgttttctgg agtctcatgg taactggcgg actctgttat
    17521 acagttggag ctggatttta tgccaagaaa aaaccttatt tccacatgat ttggcatctc
    17581 tttatcctag ctgcgtccgc actccaatac atcgctattg tttattacat gtaaaaaagt
    17641 tgagaagttc aatctcaact tttttcttta cacatattga taaagtactg gtgcaagcgc
    17701 acatcatcag tcaattctgg atgaaaagaa cttaccaaca tatttttttc ttgggctgca
    17761 acaatttgat tgttcactgt tgctagaatt tctacaccct caccaacact actgataatc
    17821 ggaccacgga taaaggtcat tggaatcttg ccaactccct tacattctgc ttccgtgtag
    17881 aaacttccta attggcgccc ataagcatta cgctcgacca ccatatccat agttcctaga
    17941 tgactctctt tctgagaagt gatttcctta gccagcaaaa ttaagcccgc acaggtccca
    18001 aacactggta agccagatag aatggcttct cggatgggaa gtagcatgtt ctggtcacgt
    18061 aagagcttgc ccatggttgt agactcacca ccaggcaaaa tcaaacccga caagtcactc
    18121 tgatcttgct gaaaatcatc tagatttctg agttctacac tctcgacacc taattgatct
    18181 agcacttttg catgttctgc aaaggcccct tgcaaggcca atattccgat tttcatctat
    18241 tttcctcgtt cagccatgag aatttggatt tcattttcat taataccaac catggcttct
    18301 cctaaatctt cagagatttg agctaggatt tgaggattac ggaagttagt cacagcctta
    18361 acaatggcac tcgctcgttt aacaggatct cctgacttga aaatacctga accgacaaag
    18421 accccctctg cccctaattg catcattaac gcagcatctg ctggcgttgc aacacctcca
    18481 gcagcgaaat ttacaactgg caattttcca tgttcatgaa catattggac caattctaca
    18541 gggacttgca aatccttggc agcaacataa agctcgtcct cacgtaagtt ttgaatgcgg
    18601 cgaatttcct gattcatcat acgcatatga cgaacagctt ggacgatatc ccctgtccct
    18661 ggttctcctt tggtacgaat catggaagca ccttcagcga tacgacgcaa ggcttcaccc
    18721 aaatccttag caccacagac aaaaggaact tggaattctt tcttgtccac atggaaacgg
    18781 tcatcagctg gagatagaac ttcactctcg tcgatataat caatttcaat agcctctaaa
    18841 atctgagctt caacaaaatg cccgattctg accttagcca ttactggaat actaaccgct
    18901 tcttggattt ccttaatcat ctttgggtcg ctcatgcggg aaactcctcc agctgcacga
    18961 atatcagccg gaattcgttc caaggccatc acagctgccg caccagcagc ttctgcgata
    19021 cgagcctgtt caggattctg cacatccata ataacaccac ccttgagcat ctgtgccaag
    19081 tttttattta gttcataacg attttcagtc atttgtttta tcctcatcat ttgtattggt
    19141 agctaccttt tcattttaag tcagaacaga atgaagcaca agataaaaaa actataattg
    19201 tatggggaca gattggctaa aaactatctg accttaactt aaggccagat agctcattca
    19261 tttctatttt tcagccgtaa gggcagccat tgtgatgtag ttgtatggtt tgttgaagtg
    19321 tggcaagaag aagaggtctg tcaatgccaa tttatcaatt gtcacatgct cttggatagc
    19381 aagtgagaac atgtggattc ccatgctaat tgcaatatca tgtgaaacca tttgggcacc
    19441 aagaatttca cggctatctt tgtcaaagac aatcttaatt gctacttcat ggttgtcatg
    19501 tttcatgaat tctggttttt gaagatcgtt aaagcctgtt tcagttgcgt tgtaaccagc
    19561 agctttcgct ttttcaagag tcaaaccagt tgaaaccatg tgaagaccgt agattgagat
    19621 accatttgaa ccttgaacac cgattccttc caattcatgt ccacaagcat tgtaggcacc
    19681 aacgatacca gtgcgaacag catttgaagc aagagcgata tagcttgtat ctttacgagc
    19741 attgtcataa acagtcgcac agtcaccaac agcgtaaacg cctgggatag atgtttcttg
    19801 tttcttgtct acaaggaagg caccgttgcg gaagagttcg atcttaccat ctgcaagggc
    19861 tgtgtttgga cggaaaccaa ctgcaaggat aaccatatcc acgtcaaagc tttctttgtc
    19921 agtaatcaag cgttcaactt taccgtcacc ttcgattgct ttaacagttt gacctagagc
    19981 caagcggatg ttgtgatctt ccaagttctt cgccatcatt tgtgtgaagt ctttgtcata
    20041 gtaaccgttc aagacagtat caacgatatc aacaaggaca acttcttttc caagacgttc
    20101 aaaggcttca gcaagttcaa caccgatgta accaccacca acaacggcga tacggtcgag
    20161 gtgttggctc ttgtcagaaa gtttattgat aacttcttca gcattttggt acaatttcac
    20221 gaattgtacg ttttcaagag ttgctttaaa ttcgcggttt cctttaacaa tttcaacacc
    20281 ttcgattggt ggcaagattg gtgtagaacc tgtagcgaaa atcaattttt cgtatgattc
    20341 tttgtgctct tttccttcaa cttccgctgt aactactttg ttatcatagt cgattgaaag
    20401 aacaggtgag ttcatgtaaa ctttagcacc tttagcttcc aatttttctt tatcagaata
    20461 gaacaagcct tcagcaccgt caatttgttc accaatccaa agagccattc cacatcctag
    20521 gaaagagatg ttagagtttt ggtcaaatac aacaatttcg ttctcatttc caaaattatc
    20581 caacatggta ttgatacatg ctgtaccagc gtggttagca ccgactacaa cgattttact
    20641 cataaaaatt tcctgccttc attctaaatt taccttacta gtataccatt taccgttagc
    20701 gtttacaagg ggggtactat tatttcagca ttttttatca aaaataattc cccatttatc
    20761 ctgttttcaa gcctcatgaa ttttatgagc atatttcttg actttttcca aattttgttt
    20821 gtgaaaattc taactttatg gtattataat aacatgaaaa tgaaatgtaa gggcttcaat
    20881 ttagatgatt atttgatatt acaacttatt ttctataaga gaaaggagtt ggtagcttga
    20941 ctcttcgttc acattctgaa cggctaatgg ggactactat cactatttca ttagtggatg
    21001 agcaagccga tatctttctc caaaaatcct ttgacttgct caaagaactt gaataccgct
    21061 tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa ttatcaagca ggaatagccc
    21121 ccgtcacggt tcatccagac ctgtttgagc tgatttcact tgggttagag catagcctag
    21181 cgctctctag ccacctcaat atcagcattg gtcccttaat tcaaacctgg cgtatcggtt
    21241 tttcagatgc caaggtcgcc cagcctcaag aaattgaatc ggtgctgcct ctaatcaatc
    21301 ctcatggtat cgagttagat tcttctactt ctactgtgtt tttaaaacag aaaggaatga
    21361 agattgatct aggttgttta gccaaaggat acagtgcgga taaggttgcc caatttctta
    21421 ggaaagaggg ggtgacttct gccttgatca atctgggagg gaatatcctg accattggaa
    21481 aaaatcaggc aagaggggat aacccatggc aaatcgggat tcaagaccca gccaatccta
    21541 ggggaaatca tttaatgacc atccctgttg tcaataaatc tgtcgtgact tcaggcattt
    21601 atgaacgtca cctgaccgtc gatggacaag attaccatca catttttgac agtcaaacag
    21661 gatatcctgt tgaaacggaa ctagcgagtc taacaatcat ctctgataaa tcagtcgatg
    21721 gcgaaatctg gacgactcga ctctttggag aaagacctgc ttctatcctc tggcaagtcg
    21781 aaagtttgga gggcatcgaa gtcatcctca tcgataaaga aggccaccta agctgttctt
    21841 caggaattcc tactctatag agacaactgt ttcaatggaa ttttaaaatt gtattatgta
    21901 aaaagagaaa ggaaatctca tgttaaaact tattgctatt gttggaacaa attcaaaacg
    21961 ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac tttgctgaca aagctgaaat
    22021 tgagcttgtt gaaatcaagg ccattcctgt cttcaacaaa ccagctgaca agcaagtacc
    22081 tgctgaaata ttggaaattg ctgctaaaat cgaagaggca gatggcgtta ttatcggtac
    22141 tcctgagtat gatcactcta ttccagctgt tttgatgagc gctcttgctt ggttgtctta
    22201 tggtatttac ccacttttga acaaaccaat catgattaca ggtgcttctt acggtacgct
    22261 tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg aatgctcctg aaatcaaggc
    22321 aaatgttctt ccagatgaat tcttgctctc acactctctt caagcattta acccaagtgg
    22381 cgacttggtt gaccttgatg ttatcaagaa attggatgcc atctttgatg acttccgtat
    22441 ctttgtaaaa atcacagaaa aattacgtaa tgcacaagaa ttacttcgca aagatgctga
    22501 agactttgac tgggaaaatt tgtaagatag gagaccaaaa agaatgaaat ttgttggact
    22561 tgttggatca aactacgatc aatcatataa ccgtaagctc ttggaattta tccgtcgcca
    22621 cttcaaactc aaatttgaat tagaagttct tgaaattgac gaagttccaa tgtttaacca
    22681 agatgaaaaa tgggatgaaa gtttccaatt acgttattta tataacaaaa ttactcgtgc
    22741 agatggtgtt atcattgcta ctcctgagca taaccacact atctcagctt cactcaaatc
    22801 tgtacttgaa tggctttcat acgaagttca tccatttgaa aacaagcctg ttatgattgt
    22861 gggtgcatca tactatgacc aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct
    22921 tgatgctcca ggtgttaatg cctacacgct tccaggtaac gaattccttc ttggtaaagc
    22981 taaggaagct tttgataaca acggaaatat caccaacgaa ggcactgtta aattccttga
    23041 aacttgctta gataactttg ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa
    23101 accaatcgaa tcagaagact tggattgtgg aaaaccaatc gctacaacca tcacagaagt
    23161 tgaccctgac gatccagaat gggtagaaaa agttgcagca atcactggtg ctgtttctgg
    23221 tgatacctat gtcaaattgg accacggtat cctaacagtt aaccaaattg atatgttctt
    23281 gaaagctatg ccatttgaat tgacatacgc tgacgacaac aaccaattcc tctactacaa
    23341 caacgctcac caagatccag acactatgtt cgctaaacgt gtaccacctc aatcaggtag
    23401 ccgtatgtcg actgttcatg gttctcttcc accagcacgt atgaagaacg tagagtgggt
    23461 tatcggaaca cttcgcaacg gaaaccaaga atacgtccgt acgatcgttc caggttctcc
    23521 tgcaggtgtt atcaacactc acaactacca agcaatgtac tatcctgatg gatcatacgc
    23581 tggtatcaat gaaatcgtct ttaacttcca accatggctt gactggtacc taaaagagac
    23641 tggtcaacgt ttggtgggtg gtagcggacc atttgctcct gctgccggag gtcatggaga
    23701 cgccgatgct acttctggcg cttctgattc aggggatgct ggaggccacg gtggtgacgc
    23761 agacgctaca gccggtgcaa gttactaatg atagttttta ggaaccatta tggttccttt
    23821 tttagcgaaa aaagactagc aaacacaaac tgctagtctc tttgttatcg tttcatctat
    23881 ctttgttaaa agaaagagta catattatga atttgggtca tcaagactac ggccatgtaa
    23941 tcctttttca cgttgtactt ggcgtagttt ttctggtgta acatcgtttc cttcttcgtc
    24001 cacaattttg attccttcaa tgtgatgacg aacagcgcga cgataacctt cgatgtactc
    24061 ctcacgtagt ttggcttgtt ccactttttc ttctagtgtt aagccttctg tttttttctt
    24121 tttagcaagc tcattgatac gagcaatttt tttcggatcc atttcttctc ctttgtaata
    24181 agataaagtc cgtttatcaa attttattta gtgttaattt ggttaaaaca agcaaactta
    24241 gctgctttct tggttagttg tgacaagatt gccaaacgat tttgacggac agcctgatct
    24301 tcagccatta ccatagtatt ttcaaagaaa gcatcaatga ctgggctaag cgcaaagagt
    24361 tgtttcaatt gctgacttgc aggtcctgat aaaacgagtg tttctactgc ttctgccaaa
    24421 gctttttctt ggtcattctc aaatagtgct gaatcaactg tagcaccccc ttctgccttc
    24481 tcagccaggt taaaggcacg agaaagtgat tcaacagatg gtttaaaatc ttcttccttg
    24541 cttacttcta cgagagcact tgctgcttcc aacatatctg ccacaacaaa gtttgaacct
    24601 gcaagaactg cttccttgat atcttttgga gtagagccca tcatcttatc aacacgagcc
    24661 ttgataaagt ccataacctc tgctttattt tcataagtca aactgtcaaa tttcaatgca
    24721 taaaggctat caatcagctc atccatagca atgtgccaac caaaggcatc caagatacga
    24781 accacacctt gagttgcacg acgaagggca taagggtcat tagaacctga tggaatcaat
    24841 cctactgaga agaaactcaa aatcgtatcc aatttgtctg caatggctag aactgcgccg
    24901 accttgctct ctggaagttc tccttcagct gatgtaggca tgtagtgttc acgaatagca
    24961 gctgccaccg ctggagtttc accagcaaga agggtgtatt tttcacccat aattccttgg
    25021 agttcgtcaa attcaccaac catacctgtc aataagtcaa acttgtaaat ggctgctgca
    25081 cgagcaaggt caactgtttc atccactgac aaaccagctt tttctgccaa aagtacagtg
    25141 atttgacccg tacgaatcat gtgttcacga agggaaccaa tcttctcatg gaaggtgaca
    25201 ttgtttaatt tttcaacaag atctgaaatc accaattttt ggtcttcacg ccagaagaat
    25261 tctccgtctt ccaagcgggc taccaagact ttttcatttc ctttgatgac atttttcaaa
    25321 cgctctgcgt ttccgttacg aacagaaatg aagtttggca agagttttcc atcttgatca
    25381 cgaacaacaa agtaacgctg gtgttccttc atagaagtca ccaagacttc ttctggaact
    25441 tcaaggtatt tagcatcaaa acttcccatg aaggcagttg ggtattcaac caaattcaag
    25501 acttcattca gcaaatccgc atcaatttcg atacgtacac catgttttgc ctcaatttcc
    25561 ttgatttggt caacaatcat ttgctcacgt tcacatggat ctgcgattac aaactgctta
    25621 cgaaggtctt cttcatagct caatgctgac tgaattttgg tttctttccc caagaaacga
    25681 tggccacggc tcacacgact tcccttgata tcaaggaaat ccaagtcaaa ctcttgctca
    25741 tccaagagaa cagttaaagt gtggacagga cgaatgtatt caaagctgtt tccagcccag
    25801 tgcatgctga cagggaaagt caatgacttc aagacatcta caacaccagg aacaatggct
    25861 tcaactgctt gaccaacttc ttccttagtg acatagacat attcttcacc cttgatttca
    25921 cggaattcga tatcttcaac agtcaagcct tttccacgga caaatccttg agctgctttg
    25981 gtgaagtttc catcactatc caaggcaatt ttctttgctg gtcccttgaa atcttctgtc
    26041 aaatcagact gtttgtctga taaaccagtc acacgaacag ccaaacgacg tggtgttgag
    26101 aaggtttgaa tggcttcaaa agacaggcgt tttcccttga ggaaggctgc cattttttcg
    26161 cctagttgtt tttcacttgg tgtgacaaca taggctggta attcttcaag accgagttct
    26221 actaataagt tttttgtcat gttttttctc cgaaaagtat ctttttattt tccagtttgc
    26281 cttatgtgat tggcacgcaa gcaaccaact tcgttgtttc attgctaaaa ttggagccaa
    26341 aagtctccaa ttttgcctag tatccttagt ttcactaagg ataccttcat cactgcggca
    26401 actggctcag ggctcactct gttcgcccat tttcgtaatt tgtcactctc tttattctgc
    26461 gtcttctgct aagagtttag ctcgtgtttc ttcatccaaa agtgggtagc ctagtcgttt
    26521 gcgttctgcg acaaaggttt tggctacgac acgggccaag ttacggatac gagcgatata
    26581 gcctgcacgc tctgttacag atacggcacc acgcgcgtca agcagattaa aggtatgtga
    26641 acatttgaga acatagtcat aggcagggtg taccaagcct tcttctaatg cacgaccagc
    26701 ttctttttca aacttatcaa aattttcaag caacatttct tggtccgaaa tttcaaatga
    26761 atattttgag tgctcatact caggctggat aaagatttct ccgtatttta caccatcagc
    26821 ccactcgata tcatagacag agtctacttc ttgaatgtaa gaagccaagc gctccaaacc
    26881 ataggtaact tccgcagtca cagggctagt tgccaatcca ccgacttgtt ggaaataagt
    26941 gaactgagtg atttccattc cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt
    27001 tgatgggttt tcccagttgt cctcaacaaa acgaatatcg tgctccaaag gattgattcc
    27061 caatttttcc aaagactcaa ggtaaagttc ttggatattt gatggagaag gcttcatgac
    27121 cacctggaat tggtggtgtt ggtagagacg gttagggttt tccccataac gaccgtcagc
    27181 aggacgacgt gatggctcta cataagctgc attccatggc tcaggtccga tagcacgaag
    27241 gaaagtgtaa ggactcattg tccccgcacc tttttcattg tcataagcct gcataagcat
    27301 acaaccttgg tcattccaaa attgttgcaa agtcaaaata atttcttgaa atgttaattt
    27361 cttagacatt gaatactcct taataaaaaa tgatttcttg cgacacgagt ctgcctcgtc
    27421 gattatacga ggcaagacga gttagtactg cgtctagctc agcaccctag tgctgagcgt
    27481 ggggcagtcc gactgtaagg aggtttctgc cactgacgca gtgaaatgtc aatttcttag
    27541 acattgttta ctccttttta tataaattac ttgcgacacg agtctgcctc gtcgatcata
    27601 cgaggcaaga cgagttagta ctgcgtctag ctcaggcact ctagtgctga gcgtagggca
    27661 gtccgactgt aaggaggttt ctgccactga cgcagtgaaa tgttaatttc ttagacattg
    27721 aatactcctt aataaaaaat aatttcttgc gacacgagtc tacctcgtcg attatacgag
    27781 gcaagacgag ttagtactgc gtctagctca gcaccctagt gctgagcgtg gggcagtccg
    27841 actgtaagga ggtctctgcc actgatgcag tgaaatgtca atttcttaga cattgtttac
    27901 tcctttagtt tttatatttc tttttcaatt aatttctgct gaacaaacca atctaacaag
    27961 ggaaaagttt tttctgtatt tgcccataaa tgataagaat ctaagaccgc ttgtacacta
    28021 cctaaatttt ctaccaactt atctactgtc aaaaagctgc gccagtattc ataaaaaata
    28081 cttgcatagt tcttatcata agtcgaagaa ccaaaatcat tcaatgaatg ccaactatac
    28141 ttcttctgaa aaagttctac gagagattga ttacaaattt tttccgcttg aaattcctct
    28201 tctgtcaaga aatacttgcg actaatatat tcaaccatcc cctcttcgaa ccagatataa
    28261 gagtcataac cattcgtcta ttatttgtat aggctggaac agcgctttcc ctaataatct
    28321 gtgtagcagc attaaaatct gaccaaataa cggcttgcgg taaatcacag actgcaagtt
    28381 cattctttaa aaaagattga taatctttca acttttcagt atttcttact acaaaatcac
    28441 gaaatgtagc tagttgacta tcgtctttta caagataaag gttgtccacg gctctccttt
    28501 ctttcacaca atagactgaa taagcaaaag aaccgcgtcc gacaatccta ggttgattta
    28561 acctaggggc gtcagaaacg cggttccacc ctaatttatt acttcattgt ttttgaaaat
    28621 actacagaaa gcgccagctc attattttgc cctacttggc tcccactatc ccaagctcgc
    28681 ttgaagaacg ccataagact ttctttcctg ctgactatta tatcaaaaat tagaataatg
    28741 tacaattctt tttatgattt tctagaaatc cacatcatca actcgtggag cacccgattg
    28801 aacagcaatc gtttttaagg tttctctctc ctcatgactc agttcaattc caaagcaatc
    28861 aagattagct tgaatacgag aggttgtgac agattttgga agtggtaaaa atccttctgc
    28921 caagctccag gccaaggcta tctgagcaat cgattttccg tgatttgctg cgatttcttg
    28981 cacttgcttg ctatcaaata gttctccctg accaaaaggc ccccaagctt ccaataaaat
    29041 tcccttttca cgacagtaag ctacgacttg atcttgatac acacctggcg ccaagcgaac
    29101 ttgattgacc gcaggaacga tagttgcagt ttcaagcaag gcatccaaat gatggggaag
    29161 aaaattgcta acgccgatag cacggatttt cccttcttga tagaggtctt ccatcgctct
    29221 ccaaacttcc gcattgcgag ttttccatgc gtcattttct ctgagcggtt ttgggttcgg
    29281 ccaatgaatc aaatacaaat ccaaataatc caagcccagt ttttctatag atttttccaa
    29341 agcttgacga gtttgctcat aggtttgctg actattccaa agcttggtag ttacgaacat
    29401 ttcttcacgt ggaactccgc tatctttgat tgcttgacca acactttctt cattctgata
    29461 aatcgccgcc gtatcaatat gacgataacc agccttcaag gcttctaaca ctgcatgata
    29521 ggcttcttct ccatccttag ccttaaaagt tccaaatccc aatactggaa tttctactcc
    29581 attatttaat tgataggtat tcatatgctt ctccttctat tttattcatc aattatagca
    29641 taagacattt tttaagtagt actatcttct gtaaaaaata agtctgtcaa atatctaaca
    29701 gacctatttt ttcttgctta ttcatcacga ctatagtaca gctcatgagc ttttaggcga
    29761 gtattgagca tctctggtat ggtcacaaag gtataacctt gatttttcaa atactcaatg
    29821 acccttggca aggcattgac tgtcggactg tgaatatcat gcatcaaaac gatagagccg
    29881 ttagctactt gatgctgaat ttctgtcaaa atagatgctt catttttact cttccagtcc
    29941 agactatcca catcccacat gataaagctc aaatccaagc tattgcgaat atcatctgta
    30001 atagcaccat aaggtggacg catgagttta gaactagaac ccagcacttt agttagcaca
    30061 tcctcagtat cagtaatctg ctttttagct tcatcaagag agagttgcga gagaatcgga
    30121 tggctccaac tatggtttcc aacaacatga ccttcagatt ttatcctctt caccaagtcc
    30181 tcattcccag aaacattttt cccaagcaca aagaaagtcg ctttaatatc atatttagct
    30241 agggtctcta atacctgcgg ggtcgttgct ggatttggac catcatcaaa ggttagagcg
    30301 acaacttttt gatatttctt atcaaagtaa gattgataca aggccgcatc tttttcgagt
    30361 aagtacgaag attggataac atcaaagaaa gcagatactg gcaaggctat ctcttctaaa
    30421 ttttcaagca caggacttgg ataaaggata atctgactat ccttgtaatc aaaattccat
    30481 gcagacaagt cttggtcaga gaagcttttt acaatctgct cactctggtc ttgctctatt
    30541 tttttatcct ctatgaagga ggtcaactct tttatcagct gttccttagc cttactagca
    30601 tctgaaaaca gttggtcaag tgtaaaaggt tgcccatctt ctgttaagtg aacctttcct
    30661 agactggtct tttcagtctc ttcaatctta aaagcaacta aatcatagat ttgtttggtc
    30721 acattacgat taacgactcc ctttaaacct gactcttctt gctctgtata gtagaaaaca
    30781 agattgtcct tactttctag cttgtcctta acatcttgat ttatcagctc cctaacagag
    30841 gaaatcactt tctccccttg gagagggtaa taggcaatca cttcggcttg cccctgacga
    30901 aaatactcct tctgatttcc ctcactcaat tgatcatctt tctctttttt gagcaattca
    30961 atcttttgct caaaactttt ttgctggtag atcttaaaag caataaatcc gcctaatagg
    31021 caaatagaaa ttgctaaaat accaatcaaa gccaataata catgtctcgt tttcccgtgt
    31081 ctgccacgtc ccagtctact tttatccata tttatatcat aacaaatttg agcaataatt
    31141 tcaatgatac aatttggcaa tccacaattc ctctagcaag ccaaagcatc ttacatcaac
    31201 tccaacatcc gtatctgtag agattatgta gttttctatc tatggaattt ctagtagatt
    31261 gaagctagaa tagtagacct atacttctaa aacattgtta gaaatcgatt tgattgtcct
    31321 gatcgatttg tcctgttctc atttcatttt actataaaac tatgaaaagc taggtcatct
    31381 gagaagtaat tactatcgac aattgcgata gcgtatacta gtgcgatttg tttgtagctc
    31441 tggtgggtat caccttcacg ttggcgaatt ttttctaggt tttgattaac ctgactgcac
    31501 agataaggcc ataggcgatt gatgaaaaaa ttctgatgat gatcctgaat ttcgatgata
    31561 acttggattc cattatctaa ctccgccaag acgtctatac tagtatagaa atcttacgct
    31621 gagtagggca tggaaggcaa gacgtgaatg ttacttccct ccaaaatcgt cacatttttt
    31681 gctggcaagt ccagcatatc gcggataaat tgacaaatca ttagttgggc tgatacctgg
    31741 atgtctgaga atcctccttt tcctccttct attatagcac atttttaaat ctaggtttgc
    31801 tagattctat gcttctatct atttattcgg aaaagaaagc taatagctta tttgaaattt
    31861 tctcctctct gttggatagt cccgtctatc tatgttataa tgaaagaagg atttaaaatc
    31921 ggaaaaggag tatttatgct aaaattaggt gtcatcggaa ctggcgctat cagccatcat
    31981 ttcatagaag cagcccatac cagtggagaa taccaactgg tcgcaatcta ttctagaaaa
    32041 ctagaaactg cagcaacctt tgcttctcgc tatcagaata tccaactatt cgatcaatta
    32101 gaagtcttct tcaaatcttc ttttgattta gtctatatcg ccagtccaaa ctccttacat
    32161 tttgctcagg caaaagctgc cttgtctgct ggtaaacatg ttattctcga aaagccagct
    32221 gtcactcaac cacaagaatg gtttgatttg attcaaacag ctgaaaaaaa taactgtttt
    32281 atctttgaag cagctcgtaa ttaccacgag aaagccttta ctactatcaa aaacttttta
    32341 gcagataagc aagtgttagg agcagatttc aactatgcca aatactcttc caagatgcct
    32401 gacttgttgg ctggacaaac accaaatgtc ttttcagacc gttttgctgg tggagccctc
    32461 atggatttgg ggatttatcc cctctatgct gctgttcgtc tttttgaaaa agctaatgac
    32521 gcgacttacc atgctcaaca gcttgacaat agcattgacc taaatggaga tggtatcctc
    32581 ttctacccag actatcaagt tcacatcaag gctggaaaaa acatcacttc caatcttcct
    32641 tgcgagattt atacaacaga tggaaccttg actctcaaca cgattgagca tattcgctca
    32701 gctattttta ccgaccacca aggaaatcaa gtccagattc ctatccaaca ggctcctcat
    32761 acgatgactg aggaagtcgc tgcatttgca cacatgatcc agcaaccaga tctgaatctc
    32821 taccaaactt ggctgtatga tgcaggctct gttcatgagc tactatatac catgcgccag
    32881 actgctggca ttagatttga ggcagaaaaa tgaaaaccaa actaccgact gaatggcaag
    32941 aactgagtga ccaactcggt ttccaagaat tcacccccat tcaaactcaa ctatttgagc
    33001 cccttcttgc tggagaaaac ctcctaggag tgagccaaac cggaactggt aagaccctag
    33061 cgtatctcct accaagtctt ctcagactac aaaagaaaaa agcccaacaa ctcttgattc
    33121 tagcaccaaa cacggaactt gctggacaga tttttgatgt atgtaaaacg tgggcagaag
    33181 ctatcggatt gactgctcaa ctcttccttt caggttcaag tcagaaacga caaattgaac
    33241 gtcttaaaaa ggggccagaa attctgattg gaactcctgg ccgtatcttt gaactcatta
    33301 aacttaaaaa aatcaagatg atgaatgtgg aaaccatcat cctggatgaa tttgaccaat
    33361 tactagatga ttctcagatt cactttgtag aaaaaatcac tcactacgca cctcgtgacc
    33421 accaactggt ctacatgagt gccacgacca agtttgatca agaaaagatt gtgccgaata
    33481 cacgcactat tgatctctct gatcaaaaat tggacaatat ccagcatttc tacatgcagg
    33541 tcgaccaacg tcatcgagtg gatatactac gaaaactggc tcatgtagag gatttccgtg
    33601 gtctagtctt cttcaatagc ctgtcagacc ttgggaatgc cgaggaaaaa ctacagtatc
    33661 gtgatatatt ggctgtttcc ctcgctagtg atgttaatgt taaatttaga aaagtcatct
    33721 tagaaaagtt taaagataac caactaaccc tgcttcttgc aactgacctt ttggctcgtg
    33781 gaattgatat cgatagccta gaatgtgtcg taaactttga tattcctaga gatagcgaaa
    33841 cctacacaca ccgtgctggc cgtactggcc gtatgggcaa ggaaggatat gttattactc
    33901 tcgtcactca tccagaagaa atcaaaaaac ttaaaaagtt tgcaagtatc cgagaaattg
    33961 tcctaaaaaa ccaagaactc tatatcaaat aaagccccat tgctctatac acatccagtg
    34021 tatggagctt ttttataagc aattcaattt tatactcatc tgctttcaaa aagcattcta
    34081 gtccatctct gattaacgat ggactttatc acctccttct ccagtccttg tatgacatct
    34141 tgaagttgat tcatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta
    34201 cga
//
LOCUS       DBEJNA010000026        33547 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEJNA010000026 DBEJNA010000000
VERSION     DBEJNA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.26"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..516)
                     /locus_tag="ACL3JB_001348"
                     /pseudo
     CDS             complement(1..516)
                     /locus_tag="ACL3JB_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(890..1039)
                     /locus_tag="ACL3JB_001349"
     CDS             complement(890..1039)
                     /locus_tag="ACL3JB_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0686069.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            1004..1123
                     /locus_tag="ACL3JB_001350"
     CDS             1004..1123
                     /locus_tag="ACL3JB_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0686070.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACL3JB_001351"
     CDS             complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACL3JB_001351"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0686071.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACL3JB_001352"
     CDS             complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACL3JB_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0686072.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3035..3562)
                     /locus_tag="ACL3JB_001353"
     CDS             complement(3035..3562)
                     /locus_tag="ACL3JB_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0686073.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACL3JB_001354"
     CDS             complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACL3JB_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0686074.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4984..10002)
                     /locus_tag="ACL3JB_001355"
     CDS             complement(4984..10002)
                     /locus_tag="ACL3JB_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0686075.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TASPASNEAATTETAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGD
                     ESKPAEEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSV
                     VLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVF
                     WEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLV
                     DMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYN
                     YGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVF
                     AGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFT
                     GYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEW
                     NYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTVQDVRLYST
                     KLEVTEKTKLRVAHKGGKGSKVYMAFSTTSDYKFDDADAWKELTLSDNWTNEEFDLSS
                     LAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAE
                     AVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAV
                     GKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLN
                     GTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYY
                     KDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMY
                     EKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVG
                     GDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYA
                     EGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNA
                     NLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFT
                     DKGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNK
                     VVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTE
                     EKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEGLTTAKQSLKD
                     LVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVF
                     EIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTA
                     PHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQE
                     HENAEMLVGEQRVIIQGRDGLLRHVFEVYENGQRRLRSTEVIQEAIPEIVEIGTKVKT
                     VPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKR
                     EDKD"
     gene            10295..11926
                     /locus_tag="ACL3JB_001356"
     CDS             10295..11926
                     /locus_tag="ACL3JB_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR0686076.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(12359..13966)
                     /locus_tag="ACL3JB_001357"
     CDS             complement(12359..13966)
                     /locus_tag="ACL3JB_001357"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0686077.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14356..14943)
                     /gene="rpoE"
                     /locus_tag="ACL3JB_001358"
     CDS             complement(14356..14943)
                     /gene="rpoE"
                     /locus_tag="ACL3JB_001358"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0686078.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15071..15520)
                     /locus_tag="ACL3JB_001359"
     CDS             complement(15071..15520)
                     /locus_tag="ACL3JB_001359"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0686079.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNYASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15525..15914)
                     /locus_tag="ACL3JB_001360"
     CDS             complement(15525..15914)
                     /locus_tag="ACL3JB_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR0686080.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15942..16592)
                     /locus_tag="ACL3JB_001361"
     CDS             complement(15942..16592)
                     /locus_tag="ACL3JB_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0686081.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKTPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16582..17145)
                     /locus_tag="ACL3JB_001362"
     CDS             complement(16582..17145)
                     /locus_tag="ACL3JB_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0686082.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGPVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17310..17544)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17598..18101)
                     /locus_tag="ACL3JB_001363"
     CDS             complement(17598..18101)
                     /locus_tag="ACL3JB_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0686083.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18294..19124)
                     /locus_tag="ACL3JB_001364"
     CDS             complement(18294..19124)
                     /locus_tag="ACL3JB_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0686084.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATIFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLVFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(19109..20791)
                     /locus_tag="ACL3JB_001365"
     CDS             complement(19109..20791)
                     /locus_tag="ACL3JB_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686085.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLISLLNQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSTDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLYIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20893..21150)
                     /locus_tag="ACL3JB_001366"
     CDS             complement(20893..21150)
                     /locus_tag="ACL3JB_001366"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686086.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(21157..21705)
                     /locus_tag="ACL3JB_001367"
     CDS             complement(21157..21705)
                     /locus_tag="ACL3JB_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0686087.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21720..22568)
                     /locus_tag="ACL3JB_001368"
     CDS             complement(21720..22568)
                     /locus_tag="ACL3JB_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0686088.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     DQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22756..24105
                     /gene="trkA"
                     /locus_tag="ACL3JB_001369"
     CDS             22756..24105
                     /gene="trkA"
                     /locus_tag="ACL3JB_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0686089.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24109..25548
                     /locus_tag="ACL3JB_001370"
     CDS             24109..25548
                     /locus_tag="ACL3JB_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0686090.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25673..26074)
                     /locus_tag="ACL3JB_001371"
                     /pseudo
     CDS             complement(25673..26074)
                     /locus_tag="ACL3JB_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            27482..27766
                     /locus_tag="ACL3JB_001372"
     CDS             27482..27766
                     /locus_tag="ACL3JB_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686091.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27759..28007
                     /locus_tag="ACL3JB_001373"
     CDS             27759..28007
                     /locus_tag="ACL3JB_001373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686092.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            28103..28321
                     /locus_tag="ACL3JB_001374"
     CDS             28103..28321
                     /locus_tag="ACL3JB_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686093.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28689..31013)
                     /gene="pflB"
                     /locus_tag="ACL3JB_001375"
     CDS             complement(28689..31013)
                     /gene="pflB"
                     /locus_tag="ACL3JB_001375"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0686094.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            31362..32423
                     /gene="dinB"
                     /locus_tag="ACL3JB_001376"
     CDS             31362..32423
                     /gene="dinB"
                     /locus_tag="ACL3JB_001376"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0686095.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(32570..33415)
                     /locus_tag="ACL3JB_001377"
     CDS             complement(32570..33415)
                     /locus_tag="ACL3JB_001377"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0686096.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         9946 a         7183 c         6198 g        10220 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtactt ccatcagcaa acttcccata atgtttctta tgtgcttcaa gtatataaaa
      541 aggcgtaaaa atacgcctat agataatggg gttgaaatag gtttattgtt gatgagattg
      601 tagataattc aattttttac ttccaatcga atattcaaaa cctccacctt ttctgcctgt
      661 aattgttcat cataaaattc aatatcttca ggattttccc cttgacaacc tcggcagaaa
      721 tattcttccg ctcgatcagg attcaaaaat cgacaagcac aaacaaaaca gtcgccatca
      781 tcatttattg agataatata gtagattgaa ataagatgta aacaaatcga ttaggaaagt
      841 taaattaatt tctagaaatt tttagcagat gtagtgtact attctagtct caatttacta
      901 tggcttcaaa tatatctttc gaaaaaatat ttacagatgt gtaattttga agcttgcaaa
      961 agttagtaaa cttgtagatt tcgatttgaa gtaacttgtt ttcttgcccg atattgtttt
     1021 tgaaattgaa tttttccata gtgactcctt gattttcttc tacacgtctg atgataaatc
     1081 taattcgcaa aagagtcaag aggatttttc gaaaaataaa tagcgaccga aatcgctatt
     1141 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
     1201 ctttcttcta tattagtatt agtaaaggtc taaataatta tcaatttccc attgtgaaac
     1261 gaaggttgca taacttgccc attcgattcg tttggcttca aggaagctag tgtagatgtg
     1321 atctccgaga gcagctttaa ccacttcatc ttctgtcaaa gctttcaaag cgttgtgaag
     1381 agttgatgga aggtctgtaa taccagcttc cttgcgctct tctgctgtca tgatgtagat
     1441 attttcttcg ataggagctg gtgcttcgat tttattttca ataccataca aaccaacttc
     1501 caaaagaaca gccatagcaa tgtaagggtt cgccattgga tccactgaac gcaactcaag
     1561 acgagttccc ataccacgtg aagcaggtac gcgcacaagt ggcgaacggt tacgaccagc
     1621 ccaagcaatg taaacaggcg cttcataacc tggaaccaaa cgtttgtatg agttaactgt
     1681 tgggttcatg atgacagtat agttgtaagc atgcttgatc aaaccgccta ggaaatggta
     1741 agctgtttct gacaactgca ttccttttgg atcatttgga tcaaagaagg cgttatttcc
     1801 ttctgcatca aacaaggaca tattacagtg catacctgag ccagcaatac caaattttgg
     1861 cttcgccata aatgttgcgt aaagtccgtg tttgcgagca atggttttaa caacaagttt
     1921 aaagatttga atcttatcac aagcacggag aacttcatcg tacttaaagt caatctcatg
     1981 ctgtccaacc gcaacctcgt ggtgactcgc ttctacttca aatcccattt tggtcaagac
     2041 attcacaatc tcacgacgtg tgttgtccgc aaggtcagta ggtgccaaat caaagtagcc
     2101 acccttgtca ttcacttcaa gtgttgggtc cccattttca tccaacttaa ataggaagaa
     2161 ttctggctct ggaccaaggt tgaaggattt gaatccaact tcttccatgt gacgaagagc
     2221 tcgtttcaaa ttaccacgag ggtcacccgc aaatggttca ccttctgttg tataaacatc
     2281 acagatcaga cctgcaacac ttccattttc atctccccaa gggaagactg tccatgtatc
     2341 caagtccggg tacaagtaca tatccgactc attgatacgt acaaaacctt caatagaaga
     2401 tccatcaaac ataaccttgt tcgacaagac cttatctaac tgttcatctg tagcaggaat
     2461 ttcgacgttt ttcatggttc ccaaaatatc tgagaacata agacgaataa aggtaacatt
     2521 tttttccttg acttcacgac gaatatctgc agctgtgatt ggcataagtt ttctccttaa
     2581 tctatgacta cttgcggttg cctaaccgcg accaaaaggt gactgtactg aagcaaaacg
     2641 cccctgttgg aggagttcat tgtgaagtgc acgacgtact tcagtctgac taaccgcttt
     2701 cttggatttc gcttcacgtt cagcatattt tttcttaatg gcagcgatat tataaccttc
     2761 agagatataa tctttgattt caagcagacg atccatgtca ttcaaggaat acatgcgacg
     2821 atttccttcg tttcgatcgg gcttgatcaa ctcttgattt tcataataac gaatctgacg
     2881 cgccgataga tcggtcaact tcataacact gccgatagga aaaacagcca tatttcggcg
     2941 aaattctttt tccttcattt acaatttcct tctttctgtc tattatagtc taaaaaaaga
     3001 caaacgtcaa ttaataatgt tataaaatgt aacattattt ttcttttttc tctaaaaaga
     3061 gacgaatacg atcaatatcg taatttacga taattgcgac aaaaactccc ataaatgttt
     3121 ctaatacacg cacaaacacg tacaaaattg tctcaccact tggaattgat agggtaataa
     3181 ttaacatagc tgctacacca ccaataaccc ctgctttgtt attcatggct acatttgtca
     3241 taatggttaa catggtgcag attggaacaa ctaccaaggt cacccaaaag gcttcgtgga
     3301 aaaaggtatt taataagaag aagaccaagg catagagtcc accgatacta tttcctagaa
     3361 tacgcgaagt cccaaaatga acactctcat caaaactctc cctcaggcta aaaacggctg
     3421 tcaaagcacc aatttgaaga cctttccagc caaaaaagcc aaaaatcaag agaactagaa
     3481 aaacagcaat acctgtttta aaggttcgca taccaagttt gaactgggat ttatcgaatt
     3541 tatatttttt aaaataactc ataatctcaa ctttctattt ccattttatc ataaatcggt
     3601 gatttttatg agtaatagtt gagaggaagc gtttttattt taagcaaaag aaaagaggaa
     3661 ctttcatccc tctcttcttt gatttattta taaaatctta tttttctgtc aaggctgcaa
     3721 gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc gtactaatcc
     3781 atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca ccaccaccga
     3841 tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgatt gtaccagctt
     3901 ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt ttggcaccag
     3961 tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat gtcaagacca aggaagcctt
     4021 cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat gcgttagctt
     4081 cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga gctttcgcaa
     4141 catccaattt gtcttcttct acaagtgagt taccgatttc gataccttgt gctttgtaga
     4201 atgtgtaagt catcccacca ccgataagga ctttatcagc tttttcaagc aagttttcga
     4261 taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat ggacgttctg
     4321 gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa ccagcaactg
     4381 ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga gctgtaccga
     4441 atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca agttcaggat
     4501 cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca accaagagaa
     4561 cttgtccatc ttcaagagcg ttgattgccg cttccaattc agcaccacga gtgacacctg
     4621 ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga gcaagtgatt
     4681 taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga attgcacgtc
     4741 caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg ttatcgttag
     4801 tgattacgcc atctttcaat ggtacgttga agtcaacacg aacgaggact tttttacctt
     4861 tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt tatttatttt
     4921 attagaaact attatatcac actttggaaa tataaggaaa gatttcacaa gatttttcga
     4981 tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag caagaccaag
     5041 gctggctaag cctgctatta gggcttcatt agcatcagct gttcctgtat ttggcaattg
     5101 tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct gtgtagctac
     5161 tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa tcgcttcttg
     5221 gatgacttct gttgaacgaa gacgacgctg accgttttca taaacttcaa agacatgtct
     5281 taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca tctcagcatt
     5341 ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt taggagcctt
     5401 ttgttgatca gaagccggtt gataagtagg ttttggaagg actttgtttt gtggtgctgg
     5461 tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag taaagtgagg
     5521 tgctgtaaag ataacatgac tatccgtttg ttcaaaagtc aattctactg cctctttgcc
     5581 ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga ttttcacaat
     5641 agaagcataa gagagatcaa catcttgacc tttttcatcc aaaccttcta tttcaaagac
     5701 atgagcatct tctccagcaa agtatttctt ctcttcagca cttgcttgaa cacgctctac
     5761 tttcaaaccc ttgatgacag tcttctcttt atttgagaag tgtacttcaa cacctgtttt
     5821 actatcagaa aagactgctg gcttgtcttc tttcaataaa gcaaccagat cttttagact
     5881 ctgtttcgct gttgtaagcc cttctggact caaatctact ttttcaacca aggccttgtt
     5941 tttctcaaga agcggagcta gagcagaacc tgaaggatgg tttggtttgg cagccaagag
     6001 ttcttgaacc tcacctgtta aacgatcaag ctctgtcttt tcttccgtaa atttctcttg
     6061 accattcaga gctttatgag cttctgtcaa tttattaagt cggtcattga cttgatcttg
     6121 ggtgctagtt tcatggtctt tcaacacttg ttcggccgct tcaattgctt tcaagaaagc
     6181 ttcttttact tctggtgaag caaagttata gaccaccttg ttcttagcag cttcaacttc
     6241 tgctaatttc tgtttgaggt actcatcgtt caatgctgct tttggagata ccaaaacatc
     6301 aaagttgact tcatgacctt ggtaacgaag cgtcaaggtt tgacgaccag tcttttgagc
     6361 atcataacca gaaatttcaa ctcccttatc agtaaaggaa tgttcttcca tggtgtcatt
     6421 gctataagcc actgcaaagc gtccttcaga caagtctaag ctatcaccaa ctaggtaatc
     6481 ttttttcggt tcctgactta cttcaattcc caaaatagtt ttcggacttg cttcgtcttg
     6541 gccagtgaca gtcactgaca aattagcatt taccggttgt cccaaatatt ggagagtaag
     6601 attctgttct cccttatgat gcgtatcaaa acctgatact gatacacctg cgtgagttag
     6661 gcgaatgagt tcgtcctcag ttcctccttc atactgaact cgaagaacac cacctctaag
     6721 gtccaaatcc tccccttcgg cgtagcttgt tttcttaggt cctgtttcta ggctgactga
     6781 cttgattctt ctgtcatctt ttggaacgga aactgctagg acattactaa tttccttgcc
     6841 tggcaactgg gtacgataat aaagaagacc agattgattt gtcaaatcca atggtgcact
     6901 tgctaggtct cctccaactt cgctcttcaa ggttgcgagt ggagtttgag aatttggatt
     6961 atcataaacg gtaatagttg ctccagccgg tacatctgca aagccaactt gtaccttgtt
     7021 attgcctaga gaacgggctg cagccttggc catcggaata ttgacactct cagtatcaag
     7081 cttttcatac attttccagt tatagatacg aatagccttc catggagttc cattgtcaga
     7141 agtgacaaca ttcaagcgcc agtcttgagc agtgattggt ttatcaagag tgatatctgt
     7201 cacgtgtgct ttgttgccac ggacttcctt ggctagcttc cactcaccat ctgcatcttt
     7261 ataataaagg tcaaagtctt tggtgttcat caagccatcg ttaacagact caccaccagc
     7321 ccctgcatga tccatgaccc atctaacaac ggtacgtggc ttggtcaaac gaatatccac
     7381 actaccactc aactgagctg aagaccattt atctgacaag ctagtaatgg taccgttcaa
     7441 cataccttca ataccttctc caccttcagt cttagggaaa gtactatcaa taactgttgc
     7501 acctggaacg atattttcag ctagtggttt tggtaggctg gtatctttta cagtcatacc
     7561 ccaatcaaag gttgtggttg cagcttctga acgaactcca tttttaccga ctgctacaac
     7621 cttcagttct tgagttgtac cctgagcact tgctgagcgg ctaacttttg gtagataaat
     7681 agttgtagaa gatgagccag ttagtaattt ccagctgtct ccatcttttt cataaacttc
     7741 atagaaatct gcatccttgt tgcctttaaa ttgcacaact gcttccgctt cttgggcatt
     7801 tttaagagat tgtttcacta cagaaaagct tgtcggcgat tgtggctctt ggtgattgtc
     7861 cgagatagtt aattgtccga ggttgaactg ataatctttt acagcacctt catgctcgaa
     7921 aaatagtttg actgcataga tggttttacc cgctagtgag ctgagatcaa attcttcatt
     7981 tgtccagttg tcagaaaggg ttagctcttt ccatgcatct gcatcatcga atttgtagtc
     8041 tgaagttgta gagaatgcca tataaacttt agaacctttt cctcccttgt gggcaacacg
     8101 aagtttggtc ttctcagtta cttctaactt agtagaataa agtctcacat cctgaactgt
     8161 cttaccggct acatcaccag agaatttaag ggaatttccg ccattatagg catctgtaaa
     8221 atcatattct gcacgaagtt tttcccctgt tgaagtctgc caccagcgcc atgttggaag
     8281 aacacctgat actgaacgat aattccactc agaatcctta gaaaccttac catctacgaa
     8341 ccatttttta ccatgacctg tattaaaaga agtagtaaaa gtattaccta ccgctggcgt
     8401 acggtccgca actaggttag caataccata ccaatctttg tcacctggtt tttggccagt
     8461 ggggtctcct tgataacctg taaagaagat atcttcattt ttatgataat cttcaccagt
     8521 ttttcctaaa cttgtaatgg tatctggggc aaataaacca agagaaaggc gcaatttccc
     8581 attttcgtct aaaatgtcat tccacttaac ctttgtcttg taggaaccac cctgttgcaa
     8641 ttccaaacct gcaaatacat cataaggatt acgaccaatc cagttggcag ttgcaatagt
     8701 gtaatcattt ttagccttat cccagttaaa gttagcaaag aagttatctg ccggaacctt
     8761 atctccttct ggttgcatga attggtagtt gtattctccc aaaccatctt gatggtaacg
     8821 tccatagtta taggtcatgg catcatacca agaatacttg attggatggt ttaccttagc
     8881 agcatattcc ttgctataga gcataaactg gcgcatcttt tctccaagag gtttaaccaa
     8941 atctccagtt gtttcttggt tgatgaaata gccatcatag ccataatact ttgccatgtc
     9001 taccaattta cgagcaattg ggaagctacc atctgcgtct tgcttcaaag cttcagcaaa
     9061 tctttcttga tctgcaatac tattagacca gttgaagaag agtgtaccgt atacaggaac
     9121 cccgttacgg tgacctgcat caataacgtc aggagttggt acgagacctt cccagaagac
     9181 cattgaatct agatattgcc aatagtcaaa agcataggcc ttgaactctt ctccaccaac
     9241 agaagcatgg tcttttgctt tagaattagt gtttgataag gcttgaactt ttgcttcctt
     9301 gctagctttt tcattgacta aatgacctgt ccgacgtgaa gcgaggacaa cagatccgcg
     9361 gttaatagca tcatcttcac gagcacctgg ttcccatttt aacaattctt cccaagaatt
     9421 aaatttgatt tcctttggtt ttaatgtttt ttctgtattt ttagggacat ctggctggac
     9481 ttctttttca gtcttattag cttcttctgc tggtttagac tcatcccctt ggttagttgc
     9541 ttcgggcttt gcttctgttt ccttgtcaga cttaggtttt gcttctgcag atggtgtttc
     9601 tgcaaccacc tcacttgctt tttcctctgg tttagctgcg ctagctgctt ctgcagtttc
     9661 agtagttgca gcttcattgc ttgctggcga agcagtttca gtagttgcag cttcattgct
     9721 tgctggcgaa gcagtttcag atgctatcgc tactccttct gccttttcta gcttgttttc
     9781 tctagcatgt tccccttcat tctgcttatc agcttcattg gtcgaatgct cactctctcc
     9841 tgaaacaagc tctgtattag ctccgctatt ttcaggaact gcagtttctt cagccaaggc
     9901 tggaccagca aataaaacag caccaatcat cagcgagcag gctcctactg ataacttacg
     9961 aatactgtaa cgacaacgtc tttcaaaaaa tggattcttc attttctcct cctaaaagat
    10021 tgattttgtt gttttcaaga aagcgctttg tattctgtgg ttttttatca aactctagaa
    10081 ccatgataat cacattttta tcctaaaaca tttttagaca aaaaacaata gctgttttca
    10141 caaatctaaa ataaggttaa aaactcttaa aaataataca cttatcaatt ataattttct
    10201 tttacaaact tgacattaac acttgttaga tttactttta tcctttaaaa tagaatagga
    10261 gatattccgc gattattttt cggaggaaaa agaaatgtcc attaattggc aggaaatttt
    10321 atttcacttt ttaggtggcc tggggctatt cttatatagt atcaagacca tgggagacgg
    10381 tttgcaacaa gctgctggag atcgccttcg tttttacatt gacaaatata ctagtaatcc
    10441 tttctttgga gttctggttg gtattgggat gactgctcta attcagtcta gttctggtgt
    10501 aacagttatt acagtcggcc tggtcagtgc cggtctctta accttacgtc aggctatcgg
    10561 gattgtcatg ggtgctaata ttgggacaac tgtcacatcc tttctcatcg gttttaaatt
    10621 aggtaactat gccctaccta tgctctttat cggtgccgtc tgtctctttt ttacgaaaaa
    10681 tcggacagtc aataatatcg gacgcatcct ctttggtgtc ggtggtatct tttttgccct
    10741 caatctcatg agcggcgcaa tggctccact caaggattta caggtcttta aggactatat
    10801 gattgagcta agtaagaatc ctgttttggg tgtctttgtc ggtactggct tgaccttgct
    10861 aattcaagct tcttcggcta ccattgggat tttacaaaac ctctacgccg gcaatctaat
    10921 tgacctacag ggagctttgc cagttctatt tggtgacaat atcgggacaa ccattacagc
    10981 catcattgcc tctttagggg ctaatattgc agctaaacgg gtagcaggag ctcatgttgc
    11041 cttcaacgtt atcggaacag tcgtctgcgt tatttttcta gttcctttta ctgtcctgat
    11101 tcattggttt gaagctacgc taaatctagc accggaaatg accatcgcct ttgctcacgg
    11161 aacctttaat attaccaaca ccattgtcca atttccattt atcggagctc tggcttactt
    11221 tgtaaccaag attattcctg gagaggacga ggttgtcaaa tacgaaccct tatatcttga
    11281 tgaacatttc atcaaacagg ccccatctat cgctctagga aatgctaaga aagagctctt
    11341 gcacttagga aactacgctg ctaaagcctt tgacctttcc tataagtaca tcattgactt
    11401 ggatgaaaaa gttgctgaaa aagggcataa aaccgaagaa gcaattaaca ccatcgatga
    11461 gcaattaaca cgttatctca ttgccctttc aagcgaagct ctcagccaaa aagaaagtga
    11521 agtgcttacc aatatccttg attcctcccg tgatttggaa cggattggag accacacgga
    11581 ggctctactc aatctgactg actatcttca acggaaaaat gttgaatttt ctgatgccgc
    11641 cttgaaagaa ttagaggaag tttaccgcca aactagtgac tttatcaaag atgctctgga
    11701 tagtgtggaa aacaatgata ttgaaaaagc acgcagtctt gtagaacgtc atgaagcaat
    11761 caataagata gaacgtgttc tcagaaaaac ccacatcaaa cgtctcaaca aaggcgaatg
    11821 ttcaacacaa gctggggtca actttatcga catcatctca cactacactc gtgtatcaga
    11881 ccacgctatg aaccttgctg aaaaggtttt tgcagaacaa atctaagaac caagaagcta
    11941 tccatcataa ttggatggct ttttactttt tcctaagcaa gactaggctg aatgaaactg
    12001 aaagagtatt ctgtagatat atagtatatt gaaactagaa tagtacacct ctatttctaa
    12061 aacattctta gaaatcgatt tgactgtcct gatagagatg ttcacatctt atttcaattc
    12121 actatacaat ccagttccta aaactttgct agaaattgat ttggctttcc gaattaattt
    12181 gttcaaattt tatttcattt caatatactg ataaatccat tcactagcac agggcaagag
    12241 ggagtcgcta tttatttcaa cggtagcagg tacatacaga ggactcctat ctcagatata
    12301 ctgcaatatc atcgtatgca aaaaacctct gagatttttc tcaaaggttc tgattttgct
    12361 aattgctgtt ctcaaccgct gcagtaacaa aggcagtgta gagttcttct ggtcggtttg
    12421 gacggcttga cagttcaggg tgatactgac aagctacaaa gaatttattt tcaggaattt
    12481 ccacgatttc taccaaacga ttgtctggag aaactcctga aaagacaaaa cctgctgcct
    12541 caaactgctc acggaaggca ttattaaact cataacggtg acggtgacgg cgttgcacca
    12601 cttcttgatt gtgataagca gcagcagcct tagagccacg tttcaactta gacggataaa
    12661 gtcccaaacg aagggttcca cccatatcct caatatcaat ctgatcacgc atgatatcaa
    12721 tgatagggta ttttgtttct ggtgcaagct ctgcagaatt ggcaccttca agacctaaaa
    12781 cgtgacgagc aaactcgata catgtcaact gcattcccaa gcagactccc aacattggaa
    12841 catcattttc acgcgcatag cggatggctt ggattttccc ttctgtacca cgttgaccaa
    12901 aaccacctgg tacgatgatc ccgtccgcat cagacaagag ttctgctaca ttctctgctg
    12961 tcacatcatt ggcattgacc caattgattt taacttctac atcattgaca tagccagagt
    13021 gtttcaaggc ttcgaccact gagatatagg catcttgcaa ctccacatac ttaccaacaa
    13081 gggaaatctt aacttgtttc ttgaggttca tgaccttgtc caccatggct gaccattctg
    13141 tcatatccgc tgctggtgcg tctaatttca aatgatcaca aacaatttgg tccatccctt
    13201 gtgcctgcaa gttcagtgga atttggtaaa ggtgttcaac atccaacgat tcgataacgg
    13261 cttctggtgc cacatcacag aactgggcca gtttattttt aattccttga ccagctggct
    13321 cttctgtacg aataaccaac atatttggtt ggattcccaa gccacgcaat tctttgacag
    13381 agtgttgggt tggtttggtt ttcatttcac cagcagcctt gaggtaagga agcaaggttg
    13441 tatggatata catgacatta tccgcaccca catctgcctt catctgacga agagcctcta
    13501 ggaatggcaa ggactcgata tctcctactg ttccaccaac ctctgtgata atgacatcag
    13561 agtcggtcgt tagagcggca cgcttgattt tttctttcaa agcatctgtg atatgaggaa
    13621 tgacttgaac agttgcccca aggtattctc cacggcgttc tttacgaaga acttcactgt
    13681 aaattttccc agttgtcacg ttggaatatt tgttgagatt gatatcgatg aaacgttcat
    13741 agtgacccaa gtccaaatct gtctcagctc cgtcatctgt cacaaaaact tccccgtgct
    13801 ggtaaggact catggttccc ggatcaatat tgatataagg gtcaaacttt tgaatggtta
    13861 ctttgagacc acgatttttc aagagacggc ctagactcgc tgccacaatc cctttcccaa
    13921 tggacgatac cacaccacca gttacaaaaa tatatttcgt agacatagat tcctctttct
    13981 aaaatgctca aggtcttgtt aactacgagg ggatatagaa aacaagaccc tactaataag
    14041 aataatctgg gacgactgca ccagattcac aactaatact cttcgaaaat ctcttcaaac
    14101 cgcgtcaacg tcgccttgcc gtagatatgt gttcctgact ttgtcagtct tatctacaac
    14161 ctcaaaacag tgttttgagc agcctacggc tagtttccta gcttgctctt tgattttcat
    14221 tgagtataaa atacaagaag ataacttctt gaaaaaacaa aaatagctcc ctaagaacta
    14281 gggagccccg acctctaaaa gaggtgccca aacaatatga tacctaaaaa taggataatt
    14341 gtcaatagct aactcttatt cctcgctggt ttcagcgtcg tcatctgaaa actcgtcgtc
    14401 gtcttcgttg agatccacat cttctcccaa gtcatctgga gcgatttcgt tgatttctgc
    14461 atcataagct tccacttcat ttttttcatc atctggattt tcatcatcgt atgaaagagc
    14521 tggatctgct tcgtatgcat cttcgtcttc tggatcatct gcattgtagt caatggcatc
    14581 tgaatcacca tccataaagg cattgacacg ttttttctta gcttttggtg ctacttcatc
    14641 gtcgtcattt tcttcaagag cgatgatttc ttcgtcgatt tcgtccacac cataccatga
    14701 acgaagaccc catttgttgt ccccaagtga gatgaagcta ccgtcaaagt tcaactctgt
    14761 gtagaacaaa ggcaaagctt cgcggatatc gctgtttgat gttccaaggt agttttgaat
    14821 ttcgtttaca agatcgctaa aatgcatctc atgatcgcga ccacgaagtt ccaagatagc
    14881 acgcgctacc tcaatcatag atagttcact tttttcttgc ccagcaaata cttctaattc
    14941 caaagcgttt ctcctcattt atactactat cgccagagcg aacagactct gacctcattt
    15001 tatcatttac tctttatttt acgataattt tgcggaatag tcaaaggtta agggggagaa
    15061 agtggcagga ttagactaat tccaatataa aactccttcc tttttctgtt gctccatttt
    15121 ccacaaatcc aagcgacttg aaacacctcc tagaagcata attgtaggtg tagatttcct
    15181 tgactctcaa ttctttccat ccttttactc gagccaattc aatcaaagca cttagaatct
    15241 tttttccaag tcctcgatgt tggtaagcgg aattcccaat cacaatgggg agattatcct
    15301 gagatagtgt aatatcccca attggaaacc attctccctt ctccttgact tcaatccaaa
    15361 aaagctcacc atgccgatcc aaataggaat acatggcttc caaggtcgct tgactgtaag
    15421 gaagcttcac cccatctacg aggtaaacca agttcacatc ctgataccaa gcaaaagctt
    15481 cctcacaatg attgacctta taataaggaa caaaacacaa tgcactacct tttcaacaaa
    15541 agagttgctg cttgattaaa accatcacac cagttatacc attttgcttc atacccatct
    15601 tgagctagga tacgatcttc taaatcaaaa acagagtaaa tctttctttc ctcgcaagct
    15661 tgcgcataga gatgatatag ttcatcacca ccatctctat cccactcagc agaaatcgta
    15721 tcccgacctg ccaataaagc ctgataagcc ctgtgatgcc catctgtaat cagcaaacaa
    15781 tctccaaagg caagaatact gattggatcg acttggattg tttctgccga ctggtaaagc
    15841 atctgaatat cttgcaactt cttttctgat aaatatagtt gagtcggatg aagatctgct
    15901 atattgactt tcatttcttt ctcctcaagg gaattcgata ctcacttctg tttgccttta
    15961 aatcgccatt ggaagcggag cttgtcatag aagggaaact cgataaacag gactcccaag
    16021 cccacacaga gactggcaag gacgtctgat gggtaatgaa ctcccagata gactcttgat
    16081 accagcacac tgactaggta gaggccaagg acgatttgta cgatttttct ccagactgga
    16141 gttttaattc gttgactgag aatgacaatc agagtaccta ccatcaaagt tacagccaga
    16201 gaatgcccac ttgggaagga aaatcccttc tcttccacca gatgtaagat agctggtcgt
    16261 gggcgctggt agatattttt aaaggtcacg attaaaagac ctgccaaagc cagatttccc
    16321 agcatgaaga aactttctat cttccatcgc ttacgataaa agacaaaagc tgtaatgaca
    16381 acccaagtga taatcactgg gatatcaatc agacgtgtga gggatcgaaa aagaatagtc
    16441 aaataatctg gtaagtctcc tcgaatggca gtctgaatcg attggtcaaa attgaccaac
    16501 atttcagggt aaaatttgac catatagcca agaataacga aaagtaaaag ggcaaaactg
    16561 cccttcatta aaaatgtttg tttatctttc atagtgtttt aaggttggtt tcaaaaggac
    16621 gtacaacaac cagaatgaaa cggaaaagat tacaccctca atcaagttaa aaggtaatac
    16681 catggtcatt aggtagttgg aaagtcccaa aatttttcca atatcaaagt tagcaaactt
    16741 agcgtacaaa ggaacagcat aaacatagtt gagaaccaac atggccaagg ttaaaccaac
    16801 agttccagct agagagccta gtaggaaacg aagggttgtc cgttcctttt tccaaatcaa
    16861 agcaaatacg atgacaaaaa ctcccaaagc tacgatattc atcggcaaac caatgtaagt
    16921 attcactcct tggctgttaa gaagcaattt caagagtgag cgaagcaaga gcactcctag
    16981 agcagcaggc aaatccatga ccaccggacc cacaaggact ggcaagatac taaattcgat
    17041 cttgaggaaa gatgccgctg gtaaaagcgg aaagtcaaag tacatcagca caaatgagat
    17101 ggctgataaa attgcaatgg tcgaaagtcg acgtgtgttt gtcataacag gttcctccaa
    17161 ttttctataa aatcagaaga agttggaaag gattcctcta tctattctca ctttttatat
    17221 cccaaaagtt ccctcttact ctattaaaga aaaacaaagc aagtggttac aatccggcta
    17281 taaatctatc aaaacagaca aagctattct ttcgtcttct cccatccaga ctatactgtc
    17341 ggttgtggaa tctcaccaca tcagcttgcg ctcgcggact tctttaaaga gaaggaaata
    17401 gagatttttc ttttagacta ggcgacaagc tgtaggcata acttctggtt aggcaaagct
    17461 tgtcaacaaa gtataaaagg aaaagatcat ttcctagtta aagtcaccgc cggtcgggaa
    17521 tcacaccctg ccctgaagac tcttttatca taacaaaaaa cgcttgcaag cgcaagcatt
    17581 ttgttcattt tcatttttta tttcaattta tccacttcat aggtatggac gagctcaaga
    17641 cctgcaaagt tctgctggcg aagagcctca tagacaatca tgcagacggt attagacaca
    17701 ttgagactgc ggacatgttc atcattcatg ggaatacgga gagccttctc aggatgttct
    17761 cgcataaaat cttcaggtaa gcccttgtct tcacgtccaa agagaaaata atggtcctcg
    17821 tcagtcgata aatccacctc agaatagact ttttccgcga atttcgaaat cagatagagt
    17881 tttcccttca tctgagatat gaaatcttcc aaactctcgt aaaaataaat ctctagctta
    17941 tcccagtaat ccaatccagc ccgcttcatc ttgcggtcat caataggaaa gcccataggc
    18001 ttgatgatgt ggaggggaga attggtcgca gcgcaagtac gcgcgatatt gcccgtattt
    18061 tgtggaattt gaggttcaaa taatacaatg tgatttgtca tgacttgctt cctttcacca
    18121 ttgcaaaaaa atagccacac tgcccggagt caagctcagc aaacagcgtg gttaaggcat
    18181 cgttaactta cctcacaaca ggtttgaagt aaatcagcga aactactttc ttagtataac
    18241 actttcagaa tcattgtcaa tagaaatgac ttgatttttt caattttttc aagctatttc
    18301 caagggttgt aaaatcgtcc ctgattctgc aagataagta gtaaactaac tactaaaaac
    18361 aaggttgcca agagcaaggt aatatagtct ccttttttca aggcctgata actataccat
    18421 gtgcgttttt tctctttccc aaagcggcga agctccatgg cagtcgcaat ggtatcaatg
    18481 cgttctagcg agctaaaaac caagggcgta ataatgagca gattgccttt gattcgttgc
    18541 ataagagaag ctttcttgga taattccatc ccacgcgcct cctgagacat cttgatagta
    18601 aagaattctt cctgcaaatc tggaatatag cgcaaggtca ggctgacaga ataagcaatc
    18661 ttatagggca caccaatttg atttaaactg gaagcaaact gactaggatg ggttgtcatc
    18721 aaaaagataa tagccagagg aatggtgcaa agatacttaa tggccaaatt tagcagataa
    18781 aagagctcct ggctggttag agtgtagaca ccgattccct gccaaatcac acttctctct
    18841 ccataaagtc caaccccata ctcgggagaa aagagataga ccatcaaaac gtttaaaacg
    18901 gcaaatatcg tcgcaaaaac ggctacaaag gaaacatctt taaagcgaat ttctgataaa
    18961 tagaggagaa agactgaaaa gatggcaatc agcaagagca ttctggtatc atagctaatc
    19021 atggccgcca atgataccag aatgaaaaag agaagtttcc cagctcctga caagcgatga
    19081 atcacagtat ctctatgctg gtaaccgatt aatttagctt gcatccctct ctcctttctt
    19141 tgtaaaatgc cgttaaatcc agtggatcca catctagttt cttagccaag ttaaagatgg
    19201 aggtttcttt tagattggct tttactaaca gctcaggatc gctcaacaga ctggctggaa
    19261 cagtatcggc aatcaattct ccatccacca tgacaagggc tcgatctgaa taatccagca
    19321 tcaattgcat atcatgggta atcatgacaa tggtatgccc ttgttgatgc agttcttcga
    19381 gaaattccat aatctcagta tagttcttct ggtcttgacc cgcagtcggt tcatctagga
    19441 ggataatttc agcgcctaag accaaaattg aggcaatagt cacacgtttt ttctgaccaa
    19501 atgacagggc agaaatgggc caattacgga attcatagag accacagatt ttcaaggttt
    19561 catagactct cgtttcaatt tcctgctcgt ccacacctcg caaacggagt cccagagcca
    19621 cctcatcaaa aatcatattg gttgaaatca tttgattggg attttgcagc acatagccta
    19681 ctcgttccgc ccgctctgca acagaatctc cttttatatc ctgtccttcc caaagatagc
    19741 ggccttcagt ctggataaag ctactcaagg ccttggctag agttgacttc cctgctccat
    19801 tttttccgac aatggcaatc ttttcaccct ttttaatatc taaatgaaga gattttaaaa
    19861 tcggtctatc atcataagaa aacgacacgt cctctagtct aaagagtgac tgcaattctg
    19921 gggtttcttt taccagttcc gtccgcaact gaacctgacc ttttgagata tacaagttat
    19981 ccagatctgc taattgttct tccttgacta aatccacacc caattgacgg agagtggtga
    20041 gataaagggg ttcgcgaatt ccattttggg tcaacaaatc agtcgccagt aactggtcag
    20101 tgctcccatt aaaaaggata cgaccatcgt ttatcaagac aatccgatcc acagggcaat
    20161 gcagaacatc ctccaaacgg tgctcgataa taagggtcgt cgtcccctcc tccttatgaa
    20221 tctggtcaat caattcgata atatcctgac ctgacttggg atcaagattg gcgagtggct
    20281 catcaaacaa gagaatcgga ctctcatcaa tcaagacacc agccagactg actcgctgct
    20341 tttgcccacc agacaaatcc tgaggacgct gattcagtaa agaaataagg tccagctttt
    20401 cagcccattt ataaacacga cctttcatct catctagggc tgtcacatca ttttccagag
    20461 caaacgccaa atcttctgcc acagacaagc caataaactg cccatctgta tcctgcaaaa
    20521 ctgtgctaac cagatgagac ttatcataga tgctcatatc aaaggctact tgacccttta
    20581 tcaaaaattc tccatatgtc tgacccttgt aaatattggg aataatccca ttcaaacact
    20641 gacccaaggt agatttacct gacccagatg gtccaacaat taagactttc tctcccttgt
    20701 aaatggtcaa gtctatccct tgcaaggtcg gttcttgttg tgtttcatac cggaaagaga
    20761 aatccttcca ctcaattata gcttctttca tcttactctc ttcattcgct tcttagactt
    20821 ctattttatc ataaatcaag cccttcttgc agtctctcct cttaaaatct tagcgccaaa
    20881 aagattccta tcctagctta cttgcctaac taatctataa acatcgaaaa agactagttg
    20941 cccagccttc cccatcattt tatactcttc gaaaatctct tcaaaccacg tcagcttcgc
    21001 cttgccgtag gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt
    21061 tgagctgact tcgtcagttc tatccacaat ctcaaaacac tgttttgagc aacctgcggc
    21121 taacttccta gtttgctctt tgattttcat tgagtattag tcctttttca aacttcctgc
    21181 acgagtttga gttcctgcat aggcaagtaa gagaagagtt cctgcaatag ctacagatac
    21241 accattggca attcccgcaa caatcccttg tgcaaatact ttttctgccg cttcttgata
    21301 aatcacaaca tctccaagtg gtgccaagac accccaaaca agggcatttg caagtagttg
    21361 aatgaggtta aaaataagaa tatctttcca gtcaaaaaca ccattgatca ctcgaacgta
    21421 ctttctaaaa agtcccacaa ctaaaccaaa gagtccgcta gcgataatcc aagtccacca
    21481 tagaccataa ccagcaagag agtccttgat tgcatgacca atcaacccga caagcaaacc
    21541 gataatcggt ccaaaaataa tagaaagtag cgcttgtacc gcatactgaa gctggatgct
    21601 tgtatttgga acaggggttg gaatgttgat catcccgatg acgacaaaga gggcagcgcc
    21661 aattccgaca gcaacaactt gtttaattgt aaatttgatt tccatactat tctcctattt
    21721 tatccttcta ttttctttat ttcaatggtc caagatgaac cgacacctac attataggcc
    21781 ttggcaaagg aaccttggtt gatagccaaa cctaaacgat agagagagtt gatgtaaagg
    21841 atgggttgcc caattctcac atctgcaaat gatttgccat agacaacctg attttgatag
    21901 accagcatat cagcatgata gatggtcact tcaaaacgat caccaaattc tggttccagc
    21961 ttgtaaaatt cttcccgtgt gatagaggtc caaagcgaac cgaaacgcac atccagaata
    22021 tcaatggctc ccttcaccag atgatcttct atgatggtcg ctacgactgg aagctctaca
    22081 atctggtcca cactgagctc tggccctact tcctcaaaag taatgtgacc actggccagt
    22141 ttagcaccag tataggcata gacatcacga ccgtggaagg tataagaatg ctctgtgttt
    22201 tgacgcctat tggccacctc agaaatctca cgaatggcta caatgccaac gtgtttcttg
    22261 ataaaggaaa gcgtcccatt atctggcgtg acaatgtatt gattttttgc agtcttggca
    22321 actacactct tacgtttcga accgacacct ggatcgacaa ccgatacaaa cgtcgttccc
    22381 tcaggccagt aatccaccgt ctgaaagaga cgatagctcc cctcaaaaat attataaggc
    22441 gtgatatcgt gcgtcaagtg atggattttt aaggttggag actcttctaa agccactcca
    22501 atcatagccg ataccgcacc atcaaccaga ccaaagtctg attgtaatac cagtaaatta
    22561 ttattcattt tatctccttg tatatccttt atcataccat atttcagaga aagtcgctaa
    22621 tagctatttc aattggttag ggtatagttt taccttatag cgaattttca ctaaaagctc
    22681 ttgttattag ctagtaggtg cattttttct tgaaaaaggg tatgatagtt acatcatgaa
    22741 aaagtaggtt ttattatgaa aattatcctt gtcggagggg gaaaagttgg ttttgccctc
    22801 tgtcgctcct tggttgcaga aaagcatgat gttttgctga ttgagcaaga cgaagctgtt
    22861 ctcaatcata ttgtcagtcg ctttgatatc attggtatcc ttggtaacgg ggccgatttt
    22921 gccattcttg agcaagccag cgtccaagat tgtgatatct ttatcgccct gactgagcac
    22981 gatgaagtca acatgattgc agcagttcta gccaagaaaa tgggagctaa agaaactatc
    23041 gttcgggtga ggaaccctga atattctaac tcttatttca aggaaaagaa tattctcggt
    23101 ttttctctta tcgttaatcc tgagctcttg gctgcccgcg ctatcgcgaa tatcattgac
    23161 ttccccaacg ccctgtctgt cgaacgcttt gctggtggac gcgttagcct catggaattt
    23221 gtcgtcaagt ccaccagcgg tctttgccaa atgcccattt ctgattttcg taaaaaattt
    23281 ggtaatgtca ttgtctgtgc gatagagagg gatcatcaaa ttatcattcc aagcggtgac
    23341 atgactgtac aggataaaga tagaatcttt gtcactggta accgtgtcga tatgatactc
    23401 ttccataatt attttaaatc acgcgccgtg aagagccttc tcatcgttgg agcaggtaga
    23461 attgcctatt atctacttgg tattctcaaa gatagtcgta tcgatacaaa agtcattgaa
    23521 atcaatcctg aaatcgccag cttctttagc gagaaattcc caaatctcta catcgttcaa
    23581 ggagatggaa ccgcaaaaga tatcctgctg gaagaaagtg ctcaacacta tgatgccgtt
    23641 gcgactctaa caggagtcga tgaggaaaat ctgattacat ctatgttcct tgacagggta
    23701 ggtgtacaga aaaatattac taaggtcaat cgtaccagtc tcctcgagat tatcaatgcg
    23761 cctgattttt caagtatcat cacacctaaa agcatcgctg tagatacgat tatgcacttt
    23821 attcgtggtc gagttaatgc ccagtattca gaccttcaag ccatgcacca tctagccaat
    23881 ggccaaatcg aaaccctgca attccatatc aaggaagcca ataaaatgac tgccaaacct
    23941 ctttctcaac tgaaattgaa aaaaggggtt cttattgcag ccattattcg aaagggcaag
    24001 actattttcc caactgggga ggatatgttg gaagttggag acaagctcct agtaacaacc
    24061 ttgttgccaa acatcaccaa gatttatgac ttgattgcga ggtaagaaat gaataaaagt
    24121 atgattcgtt acctcctttc aaagttactt ttgattgaag ctgttctcct cttggttcct
    24181 gtggctatcg ctgtctatta ccgtgaatcg agccaagtct ttacagccct cttttcgacc
    24241 atagggattc tcgtattgtt aggcggttca gggagtttac agaagccaaa aaatcaacgg
    24301 atttatgcca aggagggagt cttgatcgtt gccctctgtt ggatcctttg gtctttcttt
    24361 ggtggtctcc cctttgtctt ttctgggcaa atccctagcc ttattgatgc cttttttgaa
    24421 attagttctg ggtttacaac tactggagca agtattttga acgacatttc ggttctcagc
    24481 cgttccctcc tcttctggcg aagttttacc cacttgattg gagggatggg agtgcttgtt
    24541 tttgcacttg ctattatgga caatgccaaa aatagtcacc tagaagtaat gaaggctgag
    24601 gttcctggtc ctgtctttgg taaggttgta tccaaattaa aaaacactgc ccagatcctc
    24661 tatctccttt acatagccct cttttccctc tttgtcatca tctattatct agccggtatg
    24721 cctctctacg atagttttgt cattgctatg gggacagcgg gaactggagg atttaccgtc
    24781 tataacgatg gaattgccca ctatggtagc tcactgatta cctatctggt tagtatagga
    24841 gttttggttt ttggggtaaa tttcaatctc tactactacc ttatgctccg tcgggttaag
    24901 gccttctttg gagatgaaga gcttcgggct tacttggtca tcgtgctggt ttctacaggc
    24961 ttgattagcc tcaatactct ctacctctac ccagggtttt caaagagctt tgaaatgacc
    25021 ttcttccagg tttccaacat cattacaaca actggttttg gatatggaga tattaccaac
    25081 tggcccctct tctcccagtt tatcctcctt ttcctcatgg caatcggtgg ctctgctgga
    25141 tcaactgcag gtggactcaa gattattcga ggcctcatcc tttcaaaaat tgccaaaaac
    25201 caaattttgt caatcctatc gccccaccgt gttttgaccc tccatgttaa taaaatggtg
    25261 attgacaaag atacccagca taagattctc aagtactttg tcatctatgc tatgattttg
    25321 ctagcgctta tctttattgt cagcctagat agcaatgatt ttctggtcgt gaccagcgct
    25381 gtctttagct gtttcaataa tatcgggcct attctaggaa ccacttctag tttctcaatc
    25441 tttagtccca tctcaaaaat tctcctctcc tttgcaatga ttgcagggcg cttggagatt
    25501 tacccaatcc tccttctctt tatgaaaaga acttggtcta agagataaaa tacaaaatcc
    25561 ctctttttac aattgtgaaa gagggatttt tatattaaaa agggggaacg tttttaaatc
    25621 caagcctgtc tgtaagcaaa gttcttactc aaataaaaga tggaaaaact tactacacag
    25681 cttggtaatg ctccaataca aattgtaagg ctttacttgg attctttgtt aaatgaatat
    25741 attccattcc tctggtagca actatctgaa tacctaatct ttctgcatcc accttcatct
    25801 ctctataata actccgaact tgtggagcca gaataattaa atcataaaca cccataatat
    25861 cataatgagc tccgtacgct cctgaattcg caatcactct aacttctgct aattgagcgc
    25921 cctcgttaat tgcattggct aattacgcac ttgttccaga ccctgcacaa agaaccagta
    25981 ctttcaactc cttacttttt attacatcta tctcaccagg cattatttca cttgtatcct
    26041 cctctaaaat aatatcattt gagcttgcaa tatctataac ctgtagtaaa tatctcgtat
    26101 ttagacaata tgaaaacaag acgacttcca tataggaaac cgccttctcg ctatgttgag
    26161 tgatttatat taaaataact tttcttctag ctgcatttta ttattataaa aacattcatc
    26221 ataaccccca gaacttaaat aacaattttt attcaagata catactccta gaataaactt
    26281 tatatgaaat tctcattttt gtttttacaa ttctccttag ttaaatcttg tttaatatat
    26341 gttttacata tagtatttag cgcgacataa tactgaagtc tctctccaaa aaacggttat
    26401 gcttctttga ataggacgtt ctcacaagaa aagcatcttc acgtttcaac ttcatatggc
    26461 tcaaaaacaa tcaattgatg ctaaaacctg tacctagatg tttcggttca taaaaccatg
    26521 aaactgtaaa agtggatgaa attgatagcg atagtcaaat caagaggcat cataactcta
    26581 aaaagtcaca atatataagt tcatcctcgg aaaaatatca ttctaattgt tgaaatggat
    26641 atataaacag gggtattaac attaaatgct catgaaacaa cgaatacagg tatcaaaact
    26701 atgacaaaac aagtccctaa atttactaaa gacactgctc aactttacac ctgtaaatgg
    26761 ttgttgtata ataaagttac aaagatgtac gaccacactg ttgtaaatca tagtgttcgc
    26821 gaatatatta ctgatagcat ttctacaaat acaattgaag aggctggata ggctttaaac
    26881 gaaatatgtc agtgttttgg cattcctagc cttaatatca tttaaagaat tgtatagata
    26941 aaattttttc caatacagag actcgtaaca actgcttcat ttttctacca acatatttag
    27001 gaacaggata agatacaaga ggattaatcc ataaatcagt tctataccaa tctaagataa
    27061 ataagctaaa aaacaattga taataagcaa atagattcca aattttctct atctgctcat
    27121 tttaataaac aatactagtg taactatcct tccagtcaga agcttgtcaa atcacaccga
    27181 aaattcttct aaaatttatc tcgttaggca atcaagcaaa aactcgacga tagtacaaac
    27241 attatcatac aggattgact tcctaaatta tatactttag taaggttttc gtataagaaa
    27301 aaagattcat tttacatttc taaacattct tttctaagat gaaaaacaga atttttcgat
    27361 tgtgatttaa agcaacaaga agattttcag tatcatccta tagatacgag ctaattaaga
    27421 aaaactacat tttcgaatat aaactacaat aatataaact aaattttata ggaggaagac
    27481 aatggattgg tacgattata tgatacaggc atccaaacaa tcacaattca acgcaagcca
    27541 ttggtttcgc tatttgcgaa aagttatttt tgaagactat tcttatttaa caaaccaaga
    27601 tgtagaaaag ttgctagact ccaaagaact aacccgtttt caaaaaatta gcttgaagta
    27661 tgcctttcaa gagcatactc caactcataa atatgtgatt tcattaaata aacctgctaa
    27721 gttaaccaat gttcaaaaat tgatggagaa atacaaacat ggataaaatg aaaccggtct
    27781 tccaagccct aaataaggaa ttaattcagg aaaatctgac tttaacaatt atctgtgtcg
    27841 atggttatgt cttagaatat catggtttac gtgccacaca agatgttgat gctttttatg
    27901 accaaaatca gaaaatcaat gaaattattg ctcgtgtagg aaaacagttt aatcttaaca
    27961 tccacgaaga gttatggctc aacaatcatg ttgcaaagca aatatgaaca aacaacctcc
    28021 cttaagttta tgcgaatcct tgtactcatt tgagaatctg accgttttag tagtccctat
    28081 tgagtatgtg ttaggaatga agatgatgag tatcagagag caggatttgc aagatattgg
    28141 tgcaattatt aaatacaaaa actttcattc accattcgat acctttaaat atttaaaaga
    28201 catgggattt gatactattg acctctctgt tctattagaa ggttttagtt atgcttatgg
    28261 tatggattgg ttagaaaaat tttttaaaga aaatcaagat aaacttcgcg aattttatta
    28321 acagtatcaa acaagatgat tgtcaattag ccagtcgtct tgttttttat gatgaaatga
    28381 aataaaatct gaacaaatcg cttagagaat tccagtcaat ttctagcgct gtttgagacg
    28441 tttcagtgga ctatagtaaa atgaaataag aataggacaa atcgatcagg acagtcaaat
    28501 cgatttctaa gaatgtttta gaaataaagg tgtactattc tagtttcaat ctattatatt
    28561 tcagattcgg tccactattc cttcccaaaa acattgcata ttgcgccgaa ggaattgctc
    28621 atactatccc aagcacaaaa ccctcagtcg tttgaccgag ggttcctttt tattattcaa
    28681 gaacttgatt agctcaatgc atccaaggcg tcatccattg aaagaacttc gtggaagaca
    28741 cgttgtgtca attcagtttt ttgttctgga gtgaggtatt tagtgtttac acagtatcca
    28801 gagatacgta cgataacgtc ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc
    28861 ataacgttca agttaacgtg ttgtccaccg ttttcgaagt aaccatcaag gattgttacc
    28921 aagttatcaa cttgttcatc acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc
    28981 aatgagatac cgtcagctgc ataactaaag tcaaggctag aaagtgagtt caagttttgc
    29041 aaccaaccac ctttagcttt gttagatggg ttagcacctg gtgagaagaa ttcaagttta
    29101 gacaagttca cagaaccatc ttcgttgagg tatacacctt tgtgaactgg tgagttacca
    29161 gtttgtttag agtaagcaac gttagatgtg attgtcaaaa gtgatactgt agcttctgcg
    29221 tctttgtata gtttgtggct acgtagacga gttgtgtaag cttcgatcaa ccattctgcc
    29281 aattcgtttg aacgtgggtc atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa
    29341 tcgtagatgt agccatcttc gtcacggatt ggtttaactg tagcgtattt gatagctgac
    29401 aatgtatcaa cagtgttagc aaatccacag ataccgaatc ccatgttggc acgttgttta
    29461 gttggcaaga aggccatttg aacagcttcg tagttgtacc tatcagtcat gtagtggatg
    29521 atgttcaagg catctacgta agtgtcagtc aaccagtcaa gagatttttc aaagttcgct
    29581 ttaactgatt cgaattcaag aacttcgtca cggattggtt cgatatcaaa tactttgtag
    29641 tctttgtgaa catcgtcgta accaccattc aaaccagtaa gaagggcttt aagaacgttt
    29701 acacgagcac cgaagtactg gatgttgtgg cgttgttctt cattttctgg atcaagtgga
    29761 gacacacagc atgagataca gctcatttca ccatatccgt ctttagccat tgttgttaca
    29821 ccttcgtatt ggatagaaga gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg
    29881 tatggcaatt tgtcagtcca aagaactgtc aagtttggtt ctggtgagtt accgatgttg
    29941 tcaagagtgt tcaagaaacg gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc
    30001 ataccagcca tagaagttgt gataaaggtt gggtcacctg agtacaattg gtcataagct
    30061 tttgtacgag caaatttaac tgtacgaagt ttcataacga aatcatcaac gaattcttgg
    30121 atttctgatt cagtaaatgt accacgagca aggtcacgtt ctgcaaagat gtccaatacg
    30181 attggtacac gacctagaga tgtagcagca ccgttaatca cacggcagac agccatgaaa
    30241 gcaatgttaa cccattggat tgcttctttc acgttcatcg ctggtttgcg aacatcaacc
    30301 ccgtaaaggt cacccaggcg aacaacttgt tgcaatgctt ggtattgaag gtttacttct
    30361 tcacgaagac ggattgtttc ttcatcgatt tctttgattg cattccagtc gtttactttt
    30421 tcttgcatca agtagtctgc accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt
    30481 ccgcgtgagt atgcatctgg aagaccagtt acagtgtgtg catgacgagc gcgacgaata
    30541 tttgaagtgt aggcacggaa aataccgtcg ttaactgttg ttacatattt agtgaagatt
    30601 tcgtgaacag ctgggtctgg ttcgtatcca ttttctttta aagtagtttc agccatacgg
    30661 ataccacctt ttggcatgaa gttcaatttg aagagttcat cattttggat accaaagata
    30721 acttcatttt ctttgtcgat aaatccagca gggatatcag cgatagatgt tggacgagtg
    30781 tccattggga aacgagtttc ttcgtagtgt gctttagttt cttctacaat tttcttgatg
    30841 tgaagtgaac gctctgttgg tcctgcaagg aagctttcgt ctccatcata aggtgtgtag
    30901 ttagcttgta caaagcgtga tacacttgct ttttctttcc aatctacgcc tttgaagcct
    30961 tcccaagctt tgtcaaaaat atcttgtgct tcaacaactg tcttaacaac catattaatg
    31021 tcctcttttt tctagtaaca gtcatctgtt acattcataa gacaagtata ccataaagta
    31081 accgatttca acaagtgcaa aatccctatt tttacacttt cttttctaaa acagtctata
    31141 ttttatttca aactgtatta tatttttgaa aaaaataaag tccttttttc tttttttcag
    31201 aaaaaagggt ataataaaag aaaataagca gtaacactca atggaaatcg aaaagcaaac
    31261 taggaagcta gccgcagatt gctcaaaaca ctgttttgag gttgcagata gagctgacgt
    31321 ggtttgaaga gattttcgaa gagtataaaa aggtgctagg catgttgatt tttcctttgt
    31381 taaatgattt gtcaagaaaa atcatccata ttgacatgga tgcctttttt gctgcggtgg
    31441 aaatcaagga taatcctaaa ctcagaggaa aacctgtcat tattggaagc gaccctcggc
    31501 aaacaggtgg acggggagtc gtttctacct gtagctatga ggctcgagct tttggtgtcc
    31561 attctgccat gagttccaag gaagcttatg aacgttgtcc ccaggccgtc tttatctcag
    31621 gaaattatga gaaatacaaa gctgtgggac tccagattcg agctattttt aagcgctata
    31681 cagatttgat tgaacccatg agcattgacg aagcctattt ggatgtgaca gaaaataaac
    31741 tcggtatcaa gtcagcggtc aaaattgctc gcctcattca aaaagatatc tggcaagaac
    31801 tccatctaac tgcttctgcc ggtatttcct acaacaagtt cttagctaaa atggcgagtg
    31861 attatcaaaa acctcatggt ttgacagtga ttctacctga acaggctgag aattttctca
    31921 aacaaatgga tatttccaaa tttcatggag taggaaaaaa gacagtagaa cgtcttcatc
    31981 aaatgggcgt ttttactggt gctgatttac ttgaagttcc tgaggtgacc ctaatagacc
    32041 gttttggtag actaggctat gatctgtatc gaaaggctcg tggcattcac aactctccag
    32101 tcaaatccaa tcgcatccgt aaatcaatcg gcaaggagaa aacctacggg aagattctcc
    32161 gtgctgagga agatatcaaa aaagagctga ctcttctatc agaaaaagtc gctctcaatc
    32221 tacatcaaca agaaaaagct ggaaaaattg tcattttgaa aatccgctac gaggactttt
    32281 caactcttac caaacgaaaa agtcttgctc aaaaaacaca agatgctagt cagataagcc
    32341 aaatagccct gcaactctat gaagaattaa gcgagaaaga aagaggtgtc cgcctattgg
    32401 ggattaccct gactggattt taaagctcaa tgaaaatcaa agagcaaact aggaagctag
    32461 ccgcaggctg ctcaaaacac tgttttgagg ttgcagataa agctgacgcg gtttgaagag
    32521 attttctaag agtataaaac cttgaagagt tgccccttca aggtttttct tatacaaata
    32581 aacggacaaa actgtaaagt agcaaaacac taccaagtac gatacggtat ttaccaaaaa
    32641 gggtgaagtc gtgttttttc acatagctgg tcaagaagcg aatagccacc atgctgaccg
    32701 caaaagctac tcccatcgcg accaagagca aaaacaattg cccaaagctc aagagttctc
    32761 cggctttcac aaatttgaaa atctttaagg cactagctcc aaacataacg ggaatcccaa
    32821 gatagaaggt aaattctgtc acaactgaac gactggttcc atttaacaaa ccaccgacaa
    32881 tcgttgcacc tgaacggcta gtccctggta aaagagcaag aacttggaag agtccgatat
    32941 agaaagcggt cgtataagga agcttgtcca actctgttac acttggctcg atagcacgcg
    33001 ctttattgcg cttttccaaa tagatgaagg caaccccgta gataatcaac atgagagcaa
    33061 ctgaaaccat gttatggaag tgggtatcaa accaatcatc aaatttaaag acaccaagta
    33121 aaggtaaagt agcaatcaag accttcaacc atagtctcca agtcttacga acttcctgtt
    33181 tgtccttagt cggtttaaaa ggattgagct tgttaaaata aatcaccata actgctaaaa
    33241 tagcaccaag ctgaatcacg acattaaaca tggacataaa ggcttcattt tgattttggt
    33301 attggatgaa ttcctctgct aaaatcaagt gacctgtact ggaaatcggc aaccattccg
    33361 taattccttc aacaatcccg aagaagatag attttaaaat ttcaataaga tacatagatt
    33421 actccctata ttataattag cgcagttagc tactgccaaa gcccaagtgg tatacttgga
    33481 ataagccact gtggattagt tcatttcctc caatcgcttg acgatttccg aaaggatcta
    33541 accacag
//
LOCUS       DBEJNA010000027        32909 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEJNA010000027 DBEJNA010000000
VERSION     DBEJNA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.27"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(58..216)
                     /locus_tag="ACL3JB_001378"
                     /pseudo
     CDS             complement(58..216)
                     /locus_tag="ACL3JB_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(489..1178)
                     /gene="rplA"
                     /locus_tag="ACL3JB_001379"
     CDS             complement(489..1178)
                     /gene="rplA"
                     /locus_tag="ACL3JB_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0686097.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1386..1811)
                     /gene="rplK"
                     /locus_tag="ACL3JB_001380"
     CDS             complement(1386..1811)
                     /gene="rplK"
                     /locus_tag="ACL3JB_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0686098.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2120..2836)
                     /gene="ldcB"
                     /locus_tag="ACL3JB_001381"
     CDS             complement(2120..2836)
                     /gene="ldcB"
                     /locus_tag="ACL3JB_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0686099.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2839..3309)
                     /locus_tag="ACL3JB_001382"
     CDS             complement(2839..3309)
                     /locus_tag="ACL3JB_001382"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0686100.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGHGLKGCGPVWWVPFEEMTAETCQVKPEEIKRLVECLSSEVDKLLEIKE"
     gene            complement(3311..4348)
                     /locus_tag="ACL3JB_001383"
     CDS             complement(3311..4348)
                     /locus_tag="ACL3JB_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0686101.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYMEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KNQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(4446..5771)
                     /gene="brnQ"
                     /locus_tag="ACL3JB_001384"
     CDS             complement(4446..5771)
                     /gene="brnQ"
                     /locus_tag="ACL3JB_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0686102.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5942..6229)
                     /locus_tag="ACL3JB_001385"
                     /pseudo
     CDS             complement(5942..6229)
                     /locus_tag="ACL3JB_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6389..6967)
                     /locus_tag="ACL3JB_001386"
     CDS             complement(6389..6967)
                     /locus_tag="ACL3JB_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR0686103.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7021..8421)
                     /gene="pepV"
                     /locus_tag="ACL3JB_001387"
     CDS             complement(7021..8421)
                     /gene="pepV"
                     /locus_tag="ACL3JB_001387"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0686104.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8434..9039)
                     /locus_tag="ACL3JB_001388"
     CDS             complement(8434..9039)
                     /locus_tag="ACL3JB_001388"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0686105.1"
                     /translation="MKFLELNKKRHATKHFTDKLVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9210..10004
                     /locus_tag="ACL3JB_001389"
     CDS             9210..10004
                     /locus_tag="ACL3JB_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0686106.1"
                     /translation="MKKFSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQLQ"
     gene            complement(10186..11019)
                     /locus_tag="ACL3JB_001390"
     CDS             complement(10186..11019)
                     /locus_tag="ACL3JB_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0686107.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11009..12853)
                     /gene="uvrC"
                     /locus_tag="ACL3JB_001391"
     CDS             complement(11009..12853)
                     /gene="uvrC"
                     /locus_tag="ACL3JB_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0686108.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVLNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(12893..13594)
                     /locus_tag="ACL3JB_001392"
     CDS             complement(12893..13594)
                     /locus_tag="ACL3JB_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR0686109.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13673..14905)
                     /gene="murN"
                     /locus_tag="ACL3JB_001393"
     CDS             complement(13673..14905)
                     /gene="murN"
                     /locus_tag="ACL3JB_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0686110.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14910..16130)
                     /gene="murM"
                     /locus_tag="ACL3JB_001394"
     CDS             complement(14910..16130)
                     /gene="murM"
                     /locus_tag="ACL3JB_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0686111.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16242..17021)
                     /locus_tag="ACL3JB_001395"
     CDS             complement(16242..17021)
                     /locus_tag="ACL3JB_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0686112.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17090..18751)
                     /locus_tag="ACL3JB_001396"
     CDS             complement(17090..18751)
                     /locus_tag="ACL3JB_001396"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0686113.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18926..21148)
                     /gene="recJ"
                     /locus_tag="ACL3JB_001397"
     CDS             complement(18926..21148)
                     /gene="recJ"
                     /locus_tag="ACL3JB_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0686114.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21425..22183
                     /locus_tag="ACL3JB_001398"
     CDS             21425..22183
                     /locus_tag="ACL3JB_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0686115.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22223..22987
                     /locus_tag="ACL3JB_001399"
     CDS             22223..22987
                     /locus_tag="ACL3JB_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0686116.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23000..23677
                     /locus_tag="ACL3JB_001400"
     CDS             23000..23677
                     /locus_tag="ACL3JB_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0686117.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23687..24346
                     /locus_tag="ACL3JB_001401"
     CDS             23687..24346
                     /locus_tag="ACL3JB_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0686118.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVT
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24604..25794
                     /locus_tag="ACL3JB_001402"
     CDS             24604..25794
                     /locus_tag="ACL3JB_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0686119.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKTSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26115..26996)
                     /locus_tag="ACL3JB_001403"
     CDS             complement(26115..26996)
                     /locus_tag="ACL3JB_001403"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0686120.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFFADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27137..28465)
                     /gene="vncS"
                     /locus_tag="ACL3JB_001404"
     CDS             complement(27137..28465)
                     /gene="vncS"
                     /locus_tag="ACL3JB_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0686121.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(28462..29118)
                     /gene="vncR"
                     /locus_tag="ACL3JB_001405"
     CDS             complement(28462..29118)
                     /gene="vncR"
                     /locus_tag="ACL3JB_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0686122.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29167..29250)
                     /gene="pep27"
                     /locus_tag="ACL3JB_001406"
     CDS             complement(29167..29250)
                     /gene="pep27"
                     /locus_tag="ACL3JB_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR0686123.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29430..30809)
                     /gene="vex3"
                     /locus_tag="ACL3JB_001407"
     CDS             complement(29430..30809)
                     /gene="vex3"
                     /locus_tag="ACL3JB_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0686124.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30861..31508)
                     /gene="vex2"
                     /locus_tag="ACL3JB_001408"
     CDS             complement(30861..31508)
                     /gene="vex2"
                     /locus_tag="ACL3JB_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0686125.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31521..32798)
                     /locus_tag="ACL3JB_001409"
     CDS             complement(31521..32798)
                     /locus_tag="ACL3JB_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686126.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9296 a         7574 c         6153 g         9886 t
ORIGIN      
        1 ggggataatc tctagcccct ctcacaccac cgtacgtgcc gttcggcata cggcggttca
       61 actaactttt aacgcatgtc gttcaaggta ataatccaaa cacgaaacca gtccacgttt
      121 ttcaaggact ggttttgata tagcacgttt aagtaccgac ttctgagcta ctaattgata
      181 gtagtcgccc cagccagata ccttatccgc tatataggcc ttattatcac gttcctgttc
      241 gtagagccac gatttcgcta tcccttcctc tgacgattct tatttccagc gtcagactta
      301 aaacggtcta tccccagacc gttttaatcc gctacctcac gatagtcaga cttgggaatc
      361 gctattgggt tcaccggtag taggtgccca ccgaggactt acacctcaga tatacgacat
      421 gcccgtcgta catcaaaaaa agttgagaca tagcgtcttc aactttttta cattacttta
      481 actactgatt aaagtgagtt tacgtcaact ttgataccaa caccttgagt agttgtgata
      541 gtcaagtttg ttacgtaagt tcctttagct gtagctggtt ttgctttttg gattgtttcg
      601 ttgaaagctt taaagttttc aaccaatttt tcagcttcaa atgatacttt accgatgatt
      661 gcttgaacat tacctgcacg gtcagcacgg taagtgattt taccaccttt agactcttca
      721 actgctttag caacatccat tgttacagta ccagttttag ggtttggcat caagttacgt
      781 ggtccaagga cacgtccaag acgtccaaca agagccatca tatcaggtgt agcgataact
      841 acgtcgaagt ccaaccaacc gtcgttgatt ttagcaacaa ggtcatcttc accaacaaag
      901 tctgcaccag cagcttttgc ttcttcagct tttgcaccac gtgcgaaaac aagaacacgt
      961 gaagttttac cagtaccgtt tggcaatacc attgctccac ggatttgttg gtcagctttt
     1021 ttaacgtcga tgttcaagtt gtaagcaact tctacagttg cgtcaaattt tgcaaagtta
     1081 gtttcttttg caagtgctac agcttcttct acgctgtatg cttttgtgct gtcgattttc
     1141 tcaagagcag cacgaagttg tttgcttttt ttagccattt tctattctcc ttgtaagtgg
     1201 ttcaatcgat tttcatctcc cacgtcactt ctcgaaatga tgaagtcttg cgggttttca
     1261 gtctactatt tttctcttcc tacggcctta agctcccttg ctgtacccaa gtacaaggct
     1321 cagtcacttg cctagtatga aaagcaacta atagactgct gtgagatttt ctactgtgtt
     1381 attgattagt caacaacagt gaatcccata gaacgagcag taccttcgat catacgcatt
     1441 gcagactcta cgtttgctgc gttcaaatct ggcatcttag tttctgcaat ttcttgtact
     1501 tgtgcacgag taactgtagc aactttagtt ttattaggtg tacctgatcc tttttcaaca
     1561 cctgcagctt ttttcaaaag aacagcagct ggtggtgttt tcgtaacgaa agtaaatgat
     1621 ttatcttcgt aaactgagat aacaactgga atgatcatac cagcttggtc agctgtacga
     1681 gcgttgaact cttttgtgaa tcccatgatg ttgataccag cttgaccaag agcaggtcca
     1741 accggtggag ctggtgtagc tttaccagca gggatttgca attttacaag tttttcgact
     1801 tttttagcca tttttaaatc ctcctttgtg gttttggcgg taattagaga tttttacctc
     1861 ccacaagtat gtttttcaca tacccatcca ttatacacta tttatctgga attgcaagag
     1921 aaaagtttat tttttgtact caatgaaaat caaagagcaa actaggaagc tagccgcagg
     1981 ctgctcaaag tacagctttg aggttgcaga taaaactgac gaagtcagct caaaacactg
     2041 ttttgaggtt gtgaatagaa ccgacgcagt cagtaggtaa ggcgacgctg acgtggtttg
     2101 aagagatttt cgaagagtat taatcgacgt agtctccgcc ttcaaagcca tagtattctt
     2161 ccaaactgag accacttgca gcaatttctt tagcttcttt tcctacataa cgcaggtgcc
     2221 attcttcagc catatagcct gtttcctttt ccttgccttt gagataacgg acaacaaagc
     2281 cataatcagc tgcatgatcc aagagccatt gggctgcttt ttcttctgtc accaaatcac
     2341 catcagtccc aatcacatca aaggccaagc ctgtctggtg ttcgctatag ccaggacggg
     2401 cagagtaacg gtcagctgct gcctttccat cttggttgac ataatcttga tagagcttgg
     2461 tctgagtttc ataacttcta aaaccactgt aatgatcact aatagggaaa cctgcctctt
     2521 gcatcgcttt gatgagtttg accaactcag ccttggctgt tggattttcc ccgggattat
     2581 agtctttcga caaaggataa tgtttattgg ctacgatgat ttcgtcgtat tttccttgga
     2641 tgctgtagta atcaccttta ttgaccactt ctgctttttt ctgggcagcc ccttgagact
     2701 tactgccgac tgtcccatca gctttggctg tctgttctgt cttagctgtg ccatcttcat
     2761 tttttgcttt ttcttgtgaa caagctgcta gactcaaggc tagcaaggct gtcaagacaa
     2821 ggtatctttt tttcatttct actcctttat ttctaatagt ttatctactt ctgacgataa
     2881 acattcgact aatcttttaa tctcttccgg ttttacttgg caagtttctg ctgtcatttc
     2941 ttcaaaggga acccaccaaa ctggcccaca gcccttgaga ccgtggccat tcatatcacc
     3001 tcttcgtcta gggaaaaggt gccagtggag atgggcatcg ccatttccta gcagttcgat
     3061 attcattttc tcagcagcaa atgccttggc aactgcctct tggactagac tcatttcttc
     3121 gagaaaacgg agtcttgttt cctttttcaa atggtgcaat tcggtaacgt gttccttagc
     3181 tagaaaaaga ctatatcctg caaaatactg gtggtctcca atcacaagat agcctgtttc
     3241 caactctttg acaaagtagg gattttctcc cttcttgatg agctcaattc tctggcaaat
     3301 aaggcacata tcaatctact aaattgcttc taagataggc atcgaccatt cgttctgttg
     3361 cgaccaccga gtcaatatga gtgcgctcat aagaatgact agactcgata cccgcaccaa
     3421 gaagagcgtg tttaacttct gcacctgcag acatagccgc tgaagcgtcc gaaccataaa
     3481 atggatagat atccagcttg aatggaatat cttggttttt agccaaggtc accaaatgtt
     3541 gacggaagtc atagtgataa ggacctgaag catccttgac acagatggac actgtgtact
     3601 catctgtttg ctgatcatcc cccatagctc ccatatccac agccagatat tcgactactt
     3661 gagcaggaat attagaatta gcaccatgcc ccacttcttc aaagactgaa aaggcaaaat
     3721 gggttgttac tggcaactca atcttctctt ccatataaat acgaagcagg ttaagcaaaa
     3781 tcgctgcgct gaccttgtca tccaaatgac gagacttgat aaaacctgtc tctgtcacga
     3841 cagttcgtgg atcaaaactg ataaaatcac cgacctcaat ccccaaggca cgagtttctt
     3901 tttcattggt tactttggcg tccaaacgca cttccatatt gtcctgggta cgttctgcag
     3961 ttcctgcatc cttgtagaca tggcaagaag tttggtggat gaggatggtg cctgatactt
     4021 tttcacctgt gctagccaca tgaacggtac agttttcacc ttcaatcatg ttccaaggaa
     4081 aaccaccgat acggtccaat ttaagacgac catctggttt gacagcacga acaatagcac
     4141 ccagcgtatc cacatgagca gtcacatagc gatgttgctc atcattttga cctttgatgg
     4201 tcacattgac accaccctta gctgtgcgaa ctggctggta accaaaacct tctagagtct
     4261 tgactaaata attcgaaatt tcacgagtaa agcccgttgg cgatgcgatg gctgtcagtt
     4321 ctttgatata ttctactgtt tgattcattt cttcacctct ttcgctacct attataacac
     4381 atttatcatc ggataaaaaa agaaaatcac tcctgtagac ttggctacaa aagtgattta
     4441 agtgattatt ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac caatgagagc
     4501 aagattccaa caatggctgg caccaaccat gggagagatg ccttggcaaa aggaagaacg
     4561 ctaacaagat ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct tgcaatggca
     4621 ataactgtaa ccacagcaat tgtcaactgc atacctggtt ttgaaagggc aacaaatttg
     4681 ttgacaatga caatcataac gatagcaatc gtgattgggt acaagataac cagtactgga
     4741 attgagtact tgataatcgc atcaagaccc aaattggcaa tagcaaatcc aatcaaggta
     4801 aaggctgtcg cataaacctt gtagctgatt tgtgggaagc gctcattaaa gaactcagct
     4861 gttgacacaa tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat agctgcaagg
     4921 aagagttgag ctgttgagcc aaagatttct tgagtggctt gtgacaagat gtaaacacct
     4981 ggtgttccac ccttcatcgc ttcagctggt actgggaaat gatttccaag aaaacctaaa
     5041 ccgatgtaaa gagcgctgaa ggcaagggca acaacgatac caacaaccca aatagttgaa
     5101 atgtattctt tcttacttga aaatccaagt tgtttcaagg tttgaactgc gattacgcta
     5161 aaggccactg aggcaagggc gtccaaggta ttataacctt ctaggaaacc tgtaccaaag
     5221 gcagaagctt gataagcagc tgaagcagct tgaggacttg ttccaccata tttgatagct
     5281 cccagaacga ccaagataac aatcaaaatt gcaaagactg gcgttaaaat acgtccaatg
     5341 cggtctaaga tttttgatgg attaagcgaa atcaaatagg ctgccgcaaa atacagaacc
     5401 gtaaatacaa tcaagccaag tcctttattt gcatccgaca aaagggggct aatccctact
     5461 tcgtaagctg ttgtagcagt acgtggggta gcaaagaatg gaccgattga caagtaaaga
     5521 actgagaggt aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc gtagatatat
     5581 cctttaggat ttagcgttcc aataataagg gtcaagacgg cgataccaac gcctgaaaag
     5641 acaaaacctg cgatggcagg aagaaaatgt tctccagata gagcacctag agaaggcgga
     5701 aaaatcaagt tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt tagggtacct
     5761 tttttagcca taaaaatctc cttcatattt ataaaatact gacctagtat accacgatta
     5821 ggagtctgaa aaaagcatca cgaggcaaat attaaatgtt ttcaattttc ttaaaaataa
     5881 gaattatcta aaaataaaac tctcctaccc agtccacacc aagtaggaga aatgcaaaat
     5941 tttaaagttc ttcaaaggct aacatgccac cctggacatt gataacatta taaccttgtt
     6001 ctaataggaa ttggcaagca cgcgccgatc tcattccaga tttgcaaata atataatgca
     6061 agcgatcttt gtccaattaa tcataactat cagccaattg actaagcggt aggttgtagg
     6121 caccttctaa atgaagagct gcaaactcat ccacttctct cacatccact aaagaaagct
     6181 ggtcgttttg gtaaagctgg taaaatgcgt caaaggctat ttctttcatt ctttttcttc
     6241 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgtg cgtatgttac
     6301 cgacttcgtc agttttatct gcaacttcaa agctgtactt tgagcagcct acgactagct
     6361 tcctagtttg ctctttgatt ttcattgact ataaaatggt tttaattctt tttttcaaat
     6421 ctggcactac ttctgcctca aaccaaggat ttttggccat ccagatttga tttcgtggtg
     6481 atgggtgaac tagcggaaaa taggctggca gatagtcttt atagtgtttc accctctccg
     6541 ttaccttccc actgattttc tcctgtaaat agtaggcttg ggcatattgc ccaatcaaga
     6601 gggttaactg aatatcaggc aattcctgta agagctgcgg atgccatttt tctgcaaaac
     6661 ctgtacgagg cggaagatca cccgacttgc catgtcctgg aaagtagaaa tccataggca
     6721 aaacagcaaa ataacctgaa ttgtaaaagg tatcttcatc cacacctagc cagtcccgca
     6781 agcggtcacc acttttatct ttccagtaaa ggcctgcttc ttgagtttta agtcccggag
     6841 cctgaccgat gatattgatg cgagcagttt ttggcgctgc aaagagaggc tcaatgccac
     6901 gctctgtata gctggcattc tgcgaatccg ccatgatagc ctgtttgatt ctttcgattt
     6961 gagacatcta ctttccctcc aaaaagaagt ccaagcataa gatctcagac ttctatcgtt
     7021 ttatttgatc aattcgtaaa tagcttcggc ataaattgct gctgctcgga agagatcgtc
     7081 caaggcaata aattcattgg cttggtgcat ggtatcaatt gagtctggga acatagcacc
     7141 ataggcaact ccgcgctcta acaagcgacc aaaggttcca ccaccgatga cttgttcatg
     7201 accttgtagg cctgtttgtt tttcatagac attcaacaag gtttgcacaa gtggatcttc
     7261 cattggcaca tagtgagggg tatgaccatg ttctgataga ctgacagaag caactggcaa
     7321 gttttctagg attgatttga tttgttctgg acttgttcct tttggatagc ggatgttaag
     7381 ggcaatggta ttatcagcac ttgtttcatc gaagcggaag actccggcat tcatagaaag
     7441 agcacccatc ttttcatcca catgagcaat cttgagattt tcaccctcat gatcgttcaa
     7501 gagaatttta cctgcgatgt caaggtagtc tttggctgga ccagcaaagc caaactggct
     7561 gaggaagagg gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag caccgtgggc
     7621 tgatttacca atgatcgtca ccttgtattt gccagcttct tcttggagtt ctcctctaag
     7681 tttgtgttct gcaacaaagg catctagttt agcttgcaag tcagccaaat cacctgaaac
     7741 gactgctgtt gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa agctgtgaag
     7801 acgggcagca cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat ttcctttttc
     7861 accattgatg attggaaatt cagcatctgg tgagaaaccg aaatctggtt tggcaagtcc
     7921 tacgtgctca aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg ttccaacgat
     7981 gaagcgaact ttcttagaag ttggaagacc caattctttg atgattttca aaccatagta
     8041 acaagctgtt gtaggaccct tatcgtccga agccccgcgc gcataaaggc gaccatcttt
     8101 gatagttggt gtgtaagggt ctgtgtccca accgctacca gcaggcacca catccatatg
     8161 ggcaaagatt ccgagaactt cttctccatc accaaactca aaatgtcctg catagttatc
     8221 aacattctta gttgggtagc catcgcggtc tgcgatttca aggaatttct ccaaggcttt
     8281 tactggacca ggcccaaatg gatgctgggc atcagccttg ctgtcatcac gttctgaatt
     8341 gatttccaaa aggctaaaca agtcagccaa gaggtcttct ttgcgttttt ctacttctgc
     8401 tgtaaaatca attgctgtca ttttttcttc tttctatctt ttctcgatga tttcatccac
     8461 tggcaagcgg tagcttggtt ccaatttttc gtctgtataa cccactgtga tcaagagttc
     8521 tgggcggaaa cggtcttcga tttccaaaac ttcattaact tttgatttgt caaaaccaag
     8581 aataatgtta gaaccaattc cttggtctgt caatgcaaga accaagttca tggcaaccaa
     8641 acctgcattg agagctaggt agtcgctgac ttgttgctca ctgtaacggg caaactcagc
     8701 tggcagattt ttcataaaat attgaagttg ctcttcagaa aagttattag caccaccaac
     8761 acgggcaatc ttacgagcac gtttggctaa gtccgtatct gtaaacaagg caatggttac
     8821 aggcgctgat gatacctgtt caaaattgga accataagct aactttgcca gttcagcatt
     8881 tttctcacgt accaccacaa atttccaagg ctggctgttg tgggcgcttg gcgccaaggt
     8941 tgcaatttcg atagccgtac gcacatcttt gggatcaaca agcttatcag taaaatgctt
     9001 agtcgcatga cgttttttat ttaattcaag aaatttcata atcgatttcc ttttctaatt
     9061 ctactgcttc cattctacca taatttgaaa gagcttgcag ggatttttca tgattaagtt
     9121 tttctatcac agacataaaa gatatatatt ggtttatcag gaaagtttct gataaactag
     9181 caagtacttt acatttgaat ggagacagta tgaaaaaatt tagcctatta ctagctatcc
     9241 taccattttt ggttgcctgt gagaatcaag ctacacccaa agagactagc gctcaaaaga
     9301 caatcgtcct tgctacagct ggcgacgtgc caccatttga ctacgaagac aagggcaatc
     9361 tgacaggctt tgatatcgaa gttttaaagg cagtagatga aaaactcagc gactacgaga
     9421 ttcaattcca aagaaccgcc tgggagagca tcttcccagg acttgattct ggtcactatc
     9481 aggctgcggc caataacttg agttacacaa aagagcgtgc tgaaaaatac ctttactcgc
     9541 ttccgatttc caacaatccc ctcgtccttg tcagcaacaa gaaaaatcct ttgacttctc
     9601 ttgaccagat cgctggtaaa acaacacaag aggataccgg aacttctaac gctcaattca
     9661 tcaataactg gaatcagaaa cacactgata atcccgctac aattaatttt tctggtgagg
     9721 atattggtaa acgaatccta gaccttgcta acggagagtt tgatttccta gtttttgaca
     9781 aggtatccgt tcaaaagatt atcaaggacc gtggtttaga cctctcagtc gttgatttac
     9841 cttctgcaga tagccccagc aattatatca ttttctcaag cgaccaaaaa gagtttaaag
     9901 agcaatttga taaagcgctc aaagaactct atcaagacgg aacccttgaa aaactcagca
     9961 atacctatct aggtggttct tacctcccag atcaattaca ataacactct tcgaaaatct
    10021 cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct
    10081 agcttcctag tttgctcttt gattttcatt gagtataaga tatactaaaa gcgattggac
    10141 cagccaatcg cttttttagt ttgcattggc tattttagga aactcttaca aaaaatcaaa
    10201 aaaattcttc acatcctcta catacccatg cttttctatt aagctggcta aaagttccag
    10261 attgtgcccc tgatagttat cgtcacgacg cagttcttca tacatttcaa taaagggaag
    10321 ccccttggac ttggccaatt ctaactcagc ctcgtaatca taagcaactt tacgaaattg
    10381 gatattgacc aattccccat cttcaacttc tatcacggca tactgggcac ggtgattttt
    10441 taacgcctcc caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc
    10501 ttgacttcca taacgaagca actgcttgtg aacatgacca taaactgcca cgtccgtttc
    10561 cgcatctagc agttggtcaa atttctctgt atcattctca actagcaagt caccaccata
    10621 gttcttattt ggcaaattat gagagataga aaagcgcagt ccagcaattt ctttcttttc
    10681 cagcaaaggc aagcttcgta gccagacagt cgttgcagga tccattcgct ccatcaaaaa
    10741 ctgggtcata cgcaagagct gaacttcctg tgggtcttct aagccatatt gcccatctaa
    10801 agcctcaagg acacgatcat cccaattgcc tcgaacactt gctgtgatag gaaggtcctt
    10861 tagcagggcg actaagtcat ttgcgcctgg accaggaaga aaaatatctc ccagaagcca
    10921 atattcactg gccccttgat ttttagcatc tgcaatcact gcttctagcg ccgtcgcatt
    10981 gccatgaaca tctgataaaa ttgcgatttt atggttcatt gtggtttcct tccgtttggt
    11041 aatctactct ttcttctgct acttgaggca aggcttctcc ctgcgggttc aactttcttt
    11101 gcacagcctc tgcaacgact ctaggtaccc caacttcgac aatctcatcc acactggctt
    11161 ccttgatttt ggtcaaagac ttgaaatgct tcataagatt ctgcttgcgt ttaggtccca
    11221 gaccgtcaat cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga
    11281 aggtaatggc aaagcggtgc acctcatctt ggatgcgttg gaggaggaaa aattcctgag
    11341 aattgcgaga caagtccacc acctcaagcg gatctccaaa gagcaattca tgggtttggt
    11401 gcttatcatt cttttgcagc ccagcaattg gaatatccaa gcccagttcc tcttggataa
    11461 cctgcttagc gatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag
    11521 tcaaagcctc acgctgtact cgaccatagc gtctgcgaat gacctctctc atgctggcat
    11581 agtcgtctgg tccaacaacc gtttttatct tgtacttacg gtaatccttc ttactcggtt
    11641 taccgttgac aaagaccacc atagccgaaa cagggctagt tcccatgata ttagagttat
    11701 cgaaggactc gatacgtact ggggtcggga tttggagcaa acgtcctaga ttttcaatag
    11761 ctccttgggt cttctcgaca gatttctcta gcaggttaaa tttctgctcc agactaacac
    11821 gtgcattttt tatggctaga ttgaccagct gttttttctc tccacgttgg ggtttgagaa
    11881 tcttggtatc caccaaagcc ttgacagcct cttcgtcaat atcctgcgga atcagtacct
    11941 cattgagaac taggtgagat ttttcttgat agaattgtcc tacataggtc aaaaaatcct
    12001 catctggatc attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttaccctgac
    12061 ggacaaagaa aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc
    12121 gattttggag atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa
    12181 tcaggtcacg gtattccgcc gcacgttcaa actccatagt ctgggctgcc gctgccattt
    12241 tgccctttag ctcatcaatg attttgttat cctgcccttt cagaaaatca gaaacctcct
    12301 gggccataga cttgaaataa gtctcatcct tcttacagat ggtgtgggcc atgcattgac
    12361 cgatatggta ataaaaacag accttagagg gcgggttggt acacttacga aaagggaata
    12421 tccgatccag caaccgcttg atttcattgg ctgcccccac atcgggatag ggtccaaaat
    12481 aaagacctcc gtcctttttg acctgacgag tgataatcaa gcgtggatag cgctcattgg
    12541 tgattttgat gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttgt
    12601 tttccttgat caggttgatt tctaggagaa gtgcctcaat attagactcc gtaacaataa
    12661 attcaaaatc cacaatttca gacaccagag cctctgtctt ggtatcatga cttccacgaa
    12721 aataggaccg tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat
    12781 ttttatcctt atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa
    12841 tcaagttgtt catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac
    12901 tagtctcata tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac
    12961 ctgctggttg catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact
    13021 catgttctgc cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat
    13081 aataatgatt caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac
    13141 tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg
    13201 ccttactaga ctcagtcacg agttcaaagt taaaagcacc cgtttgattc cagttctgga
    13261 ttgcttctaa ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag
    13321 cagaggcctg tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag
    13381 gcagttgccc tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt
    13441 ctgcttgctt tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa
    13501 gcacacataa gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa
    13561 agaaagcccc tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag
    13621 aattatttta ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc
    13681 ctactatttt tttgagtaac tggatagctt tgtattttaa aggcgatgga tggtaacgga
    13741 aagtacccgc tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat
    13801 cacttccatc aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta
    13861 tgctttccaa cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag
    13921 tgtaggaacc actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactaccag
    13981 ctaaaacaat atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa
    14041 cttcaaacgt ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat
    14101 gaggattttt actcaaatca agtcgcaact tgtccaattt ttcttctagt ttactttgtt
    14161 caccttgcaa tttgctcata tactccgaaa aattcaagct tgctatgaga aactccgctt
    14221 gttctccaaa agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc
    14281 tacgttcaga ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact
    14341 ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa
    14401 aacttttaag caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg
    14461 gttctccacc tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaat
    14521 cttgaataat actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat
    14581 aagtttcata gggttttaca agcaactcta atacaccatt ttgcttggca tattctttta
    14641 actctgcata aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt
    14701 ccatatgcag accacccagc atgggcaggc tataaaccag agctgcaact tgaatttctc
    14761 cttcttgttt caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca
    14821 tctggacaga ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt
    14881 ctttcgtgag tgttgttagt gccatatact tactttctat gtttttttct taatgtttta
    14941 cggaaatcaa gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca
    15001 cccaagtatt cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg
    15061 agagagtttt caacaccacc taaattttgc cagatcatac ctcgttcaaa ggcatagcga
    15121 gccgtttcat accaagttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca
    15181 gcatatatat tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact
    15241 ctcgcttgac ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct
    15301 ttttccttct tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc
    15361 aaggctctat ttttcgctaa ctgttcttct aactcttgcg aacgtttaga aacatccaag
    15421 gtggccaagg tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct
    15481 tcattcctca aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa
    15541 tctaatagtt ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata
    15601 gcctgttttg ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc
    15661 tgaatacgag gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc
    15721 atttgttgca aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg
    15781 attaaacttt gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg
    15841 cgagcatagg acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc
    15901 aatataggtc ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa
    15961 atactagctg tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa
    16021 ttagacttaa cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg
    16081 acaaactgat catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct
    16141 ctttcctcca gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca
    16201 tattttattt tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct
    16261 aatttgaaat caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac
    16321 cactcgtgag ttccagcgct atggctatag gtcacatcaa aacctagttt tttgagattt
    16381 ttcactgcga gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt
    16441 ttggtctttt tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag
    16501 tctctaatct ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca
    16561 ggagaaaagt tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt
    16621 gtcgtaagag ccagtttgaa gcagccgtag cctcccatag aaagaccagc gataaaggtc
    16681 ttttcacgct tgctcgtcat attagggaag aagcgtttca gaacctgtgg caattcctct
    16741 gctagagccg tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta
    16801 ttgggcataa caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta
    16861 agccaactat tatgatttcc agacatcccg tgcaaaaggt acaagacggg aatatcttca
    16921 cactctggtt cttccactcg attggcatca gggtagagga cattcacccc ccactccata
    16981 tccaatactt gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt
    17041 tctataagaa aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt
    17101 ccatgactac tggtaaaatg gctgggcgac gcttggtttg atcaaagagg tacttggtca
    17161 gattgtcacg aaccttacct ttgagatctg cccagtcaaa gtcatctcct tgaagatact
    17221 cttctaccgt ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga
    17281 gataaacaaa tccacgcgtg tgaacacgag ccctagccac aattttcttc tcacgacggt
    17341 tgactgtaat agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa
    17401 caacatttcc aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg
    17461 atccagctgg aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga
    17521 agatgcgttc tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac
    17581 gatactcccc ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca
    17641 aatcacgcac atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc
    17701 cacctgcctg ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg
    17761 gagccgtagc aatatagact aggtccccat ccttgatttc tacataacga tggcgaccaa
    17821 tcgacatctt acgaagtcca ttgataggct cacccatacg acctgtctca agaataatca
    17881 actcatggtc ttcaaagcga gacatatctt taggcttaat caaaagaatt tcgttggcta
    17941 aagacaactt cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca
    18001 agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat
    18061 tactggaaac agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt
    18121 catccctaac ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac
    18181 tgaggagagc caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat
    18241 aagattcact agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg
    18301 atgtcttcaa gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa
    18361 ccactgtccc accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt
    18421 tcttaacggc atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc
    18481 caaatacagg aactttagcc tctgccaaga gatacggtag agcaccaatg gcatccgcat
    18541 gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt
    18601 ttggaatcac cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca
    18661 aaacaaaaat ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac
    18721 caccaagtgt tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga
    18781 ttatagggca attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc
    18841 ctaccattat accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt
    18901 tgatttccca actctttcct aacttctact ctttttccat caaaaaatca taaatttctt
    18961 gcaccgtacc cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa
    19021 tttgactttc tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt
    19081 ttatcgtcac aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt
    19141 gaatattaag atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact
    19201 ggtaaatagt cttgtacaat ttggcaaact gatctctagt cccataacct gtcagataat
    19261 aagccttgtc aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg
    19321 tcttcagctg agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa
    19381 gatttggcag ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt
    19441 ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga
    19501 gggcagtttg gccattccat tggttgacag acaatttaac cgctaactct agattcttgg
    19561 tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct
    19621 cacccttgga aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt
    19681 cgacctgaaa attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta
    19741 aacgttcaaa acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta
    19801 ggtttaactt attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa
    19861 cctgagataa atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac
    19921 ctccaaaggc gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt
    19981 ccacactacg agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct
    20041 gtcccaattc ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt
    20101 ccttggccaa gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga
    20161 tagactgaac gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat
    20221 gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc
    20281 gacccaaggc attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt
    20341 tggcagcaat cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca
    20401 acatttccag accatattga actaagatac gattttcatc cgtcagactc accatatctg
    20461 caatagttcc aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac
    20521 aagccaactt gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg
    20581 gatgttcagg atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt
    20641 ctgtcacaat gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa
    20701 ccccattgtc caccgtcaca atcaaggaaa tcccttcttg ctcgataaag tatttataaa
    20761 cactagcatt agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag
    20821 caccaagttg ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat
    20881 agtctccata aacaagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg
    20941 ccttgtccat atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa
    21001 acttcttcag actttcttgg ttctgaatcc ctctctcaaa caataaccga gccacctcag
    21061 gacccagtcc agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa
    21121 actgccattc ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg
    21181 cttcattata acatgattta gacgttttct ctatccagat tgctttttta taacatttta
    21241 tagtatattg aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt
    21301 gactgtcccg atcgattttt cctgttctta tttcactata gtgaattttt tcagatatga
    21361 tttgacaaga acattctttt attgtagaac cgtgttataa aatataacac aatagagatc
    21421 tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcatt
    21481 ccgcaacatc aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg
    21541 ctctgggaag tccactctta tccgtacgat caatggttta gagactgttg acaaaggaag
    21601 tctcctagtc aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg
    21661 caaggaagtc ggcatggttt ttcaacattt taacctttat ccacacaaag ctgtgttaga
    21721 aaacgtaacg cttgcaccca ttgaagttct aggaattgat aaaaaagaag ctgaaaaaac
    21781 cgcccaaaaa tatctggaat ttgtaaatat gtgggacaag aaagattcct atcccgccat
    21841 gctatctggt ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga
    21901 actcctcctc tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct
    21961 agcagttatg cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat
    22021 gggctttgct cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt
    22081 agatacgaca gatgtcgata acttttttga caatccaagc gaacctcgtg cccaacaatt
    22141 cctcagcaaa attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa
    22201 aaaattcttt ttatcagcat tattgattag ccttttcggc cttgctgctg ccaaaccagt
    22261 ccaggctgat acaagtatcg cagacattca aaaaagaggc gaactggttg tcggtgtcaa
    22321 acaagacgtt cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga
    22381 aaccgacttg gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt
    22441 tacagcacaa acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac
    22501 ctttaccatc acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga
    22561 cgcttctgga tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg
    22621 caaaaccatc ggagtcgccc aaggttctat cacccaacgc ctgattactg aactgggtaa
    22681 aaagaaaggt ctgaagttta aattcgtcga acttggttcc tacccagaat tgattacttc
    22741 cctgcacgct catcgtatcg ataccttttc cgttgaccgc tctattctat ctggctacac
    22801 tagtaaacgg acagcactac tagatgatag tttcaagcca tctgactacg gtattgttac
    22861 caagaaatca aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa
    22921 ggatggtagt ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gccatactgc
    22981 agattaagga ggacacccca tgacagattt atcatcttgg acagcctatt ttcaggattt
    23041 tggacaattt ttcaatggtt tcctcttcac ccttgcccta gcggttggtt cctttatcct
    23101 cgctatggtt ttgggcatct tctttggtgc catgtcaacc agtaaacgtc caattttacg
    23161 cattttagct cgcatctttg ttgaatttta ccaaaatact cccctcttgg tgcagtttgt
    23221 tattgttttt tatggcctac ctcttatcag tgaccatatc atcatgattc caatttattg
    23281 gacagccgtt ctctgcgtgg gactctatca cggcgcttat atcgctgagg ttattcgttc
    23341 agggattcag tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta
    23401 tatcagtgcc atgcgcttga ttatcttgcc tcaggccttc cgcatcattc tccctccatt
    23461 gaccaaccaa attgttaacc tcatcaagaa cacctctact gtagctatca tctctggagt
    23521 agacttgatg tttgtgacta agtcttggtc ggctctcaac ggaaactata taccagcctt
    23581 tttaggtgct gctcttctct actttgctct atgcttccct gttgcccagt ttggtcgcaa
    23641 gatggagcaa gccaacaaaa aagcctattc actttaggag gttactatgg aatctatttt
    23701 agaagtttta accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta
    23761 tatttctctg attgccatca tcctctctac tatcatcggt acggtgctag ctgtcacgag
    23821 aaatggcaaa aatcctgtct tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa
    23881 cgttcccaac cttctctgga tttttactat ctttttggtg ttcaaaatga aatccacacc
    23941 agcaggtatt acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg
    24001 cggtctcaat gccgtagaca agggacagta cgaagcagga atgtcacaag gcttcacctc
    24061 agcccaaatc ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat
    24121 catttctcag tttgttaccg tgattaagga taccagtctc ctctactctg ttatcgccct
    24181 acaagaactc tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt
    24241 cttcagtctt tacatcctga ttgccctcat ctacttcagc tttaacctag caatttctag
    24301 cctgtctcat atgctagcca aacgttggca acaagctgca gaataacact cttcgaaaat
    24361 ctcttcaaac cacgtcagct ctatctgcaa cctcaaaaca gtgttttgag caacttgcgg
    24421 ctagcttcct agtttgctct ttgattttca ttgagtataa acagccactc tccagttcaa
    24481 ttggagagtt ttttgatgag agtagatatt tatagacctc aatttgacac catacatttt
    24541 ctatgataaa atgtaacaaa tttatttaca acaaatcgaa atctaaatga aatggaattt
    24601 tctatgaaat cagtcaaagg actactcttt atcatagcta gttttatctt gactcttttg
    24661 acttggatga acacttctcc ccaattcatg attccaggac tagctttaac aagcctatct
    24721 ctgactttta tcctagccac tcgtctccca ctactagaaa gctggtttca cagtttggag
    24781 aaggtctaca ccgtccacaa attcacagcc tttctctcaa tcatcctact aatctttcat
    24841 aactttagta tgggcggttt gtggggctct cgcttagctg ctcagtttgg caatcttgcc
    24901 atctatatct ttgccagcat catccttgtc gcctatttag gcaaatacat ccaatacgaa
    24961 gcttggcgat ggattcaccg cctggtttac ctagcctata ttttaggact ctttcacatc
    25021 tacatgataa tgggcaatcg tctccttaca tttaatcttc taagttttct tgttggtagc
    25081 tatgcccttt taggcttact agctggtttt tatatcattt ttctatatca aaagatttcc
    25141 ttcccctatc tagggaaaat tacccatctc aaacgcttaa atcacgatac tagagaaatt
    25201 caaatccatc ttagcagacc tttcaactat caatcaggac aatttgcctt tctaaagatt
    25261 ttccaagaag gctttgaaag tgctccgcat cccttttcta tctcaggagg tcatggtcaa
    25321 actctttact ttactgttaa aacttcaggc gaccatacca agaatatcta tgataatctt
    25381 caagccggca gcaaagtaac cctagacaga gcttacggac acatgatcat agaagaagga
    25441 cgagaaaatc aggtttggat tgctggaggt attgggatca cccccttcat ctcttacatc
    25501 cgtgaacatc ctattttaga taaacaggtt cacttctact atagcttccg tggagatgaa
    25561 aatgcagtct acctagattt actccgtaac tatgctcaga aaaatcctaa ttttgaactc
    25621 catctaatcg acagtacgaa agacggctat cttaattttg aacaaaaaga agtgcccgaa
    25681 catgcaaccg tctatatgtg tggtcctatt tctatgatga aggcacttgc caaacagatt
    25741 aagaaacaaa atccaaaaac agagcttatt tacgaaggat tcaagttcaa ataagtaatc
    25801 atactctcct gggatttccc aggagagttt tttatagcca aatgaaataa gacaggaacg
    25861 atggaatttt ggcattcaaa tcaattgata agactatttt atagtggagt gaaataggat
    25921 acgaacaaat tgattaggaa aatcaaatga atttatagaa atcttttagc agttatgtta
    25981 tcctattcta gtttcaaaac gctatagaag cagcattgtg ctagtctaga ttcagtttac
    26041 tatactaaaa cgagtagctt gaaatcaaaa aacccaccct cacaggcagg ttttatctgt
    26101 attattcagc tagattatgc tttaccttct gaaccgaata cgtcgatacg ttcttcaacc
    26161 gatgcttgga tagcttttac accgtcagca aagaatttac gtgggtcgaa gagttttttc
    26221 ttgtcgtatt ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt tgcgttagcg
    26281 aatgcgattt ggcattctgt gttaacgtta actttggcaa caccaagttt gatagctgct
    26341 tggatttgct catcaggaat acctgatcca ccgtgcaata cgattgggaa tcctggaaga
    26401 gcttctgtca atttttgcaa gtggtcaagg tcaagacctt cccagtttac tgggtaagga
    26461 ccgtggatgt taccgatacc agctgccaag aagtcgatac cagtttcaac cattgcttta
    26521 gcgtcttcga ttggagccaa ttcaccttta ccgatgattc catcttcttc accaccgata
    26581 gtaccaactt cagcttctac tgagatacct ttagcgtgtg ctttttcaac aacttcttta
    26641 gccaatttaa ggttttcttc aactggaagg tgtgaaccgt caaacatgat tgaagtataa
    26701 ccaacttcga tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg gatagctact
    26761 ggtacagtga tacccattga ttcaacaagg ttagcgatca agttgcgagc aactttgtaa
    26821 ccacccatgt atttagcagc acccattgaa gtttggatca aaactggagc ttttttagct
    26881 tctgctgcgc gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa tccaccaact
    26941 gcataaccgt tgtcacgggc tgcttggaca aatttttctg ctgaaacgat tgccatttta
    27001 tcaggcctcc tgtatatttt tatgggtcat cccatttaca ttgttcattt tatcactttt
    27061 tgccaaaaaa atctagtttt tcccgcagtt tcgattgatt ttcttctaac tccatctatg
    27121 taaacccttt ctctccctag tcttggacga cttttggaaa atctataaag aaggttaaac
    27181 tattctcctc catctcgaaa cgataagcta atttttcatg ttctaataga ctcttaacca
    27241 caaagagccc cataccagac cccttgacct tgcgactggc attgtcagaa aaagactggg
    27301 ctagtttttc ttgttcctct gagctacagc tattttcgat aaaaagttct ccttctcttt
    27361 ctccaattcg aactaagcca cctggaacag agtgcttaat ggcattgctg atgagattag
    27421 aaagaatcaa cttcataact gatgggttta gataagcctg ctgatgggtc aaactattgt
    27481 ctatctggag ctctctttcc ttggctagca aggcataatc tttgaccaga ttttgcgtca
    27541 tctggaggag gtcaattgtt tccctatcat ctcgcaattc ctgcacagaa gagagggaaa
    27601 gtatctgcag aacatggtga ttgagttcat ccacaatccc caaggcaact cccagatact
    27661 ggtctctatc cttataacga ccgatattct ctctcatatt ttcgattagg attttcaaac
    27721 tagccagcgg tgttttcaat tcatgagaag ctcctcgtag gaattcgacc ttcatcttct
    27781 ccagctggag aatggcttca ttcttttcat gcaagtccgc aataacagtc aagagatgct
    27841 ggtagaggct attgatttgt tccttgagat tacctatctc atccttagaa tccacgcgca
    27901 atcgcacttg ggaatccagg tccatcatcc gacgggtcac ccgcttgatt tccaaaatcg
    27961 gtgcaacaat agtccgagcg tagatgtagg ccaccaaaag ggaaatcaga aaggaggcca
    28021 gcaaggtata gggaagaaac tggagactga tttgctccgc ttccttttgt aaatccatgg
    28081 aagctagaaa ctggagaatc atagtaccac cgtcttgcgt tttcacctcg cgctcctcaa
    28141 taaagagaga ggttgtctgg cggtctgtgt ccagaggaag actgtccttg acttctaact
    28201 tgtcctcggt catctcacct ttgacggtcc ccttgatatc actagtctgg gaatacaagt
    28261 ctaacacttg ctcgatactc tgcctatctt tcccttctag ggactgggca atggctgttg
    28321 ccttttgacc aatggtttcc tgacgatgac tcagataagt cgaaggaaaa agaaaataaa
    28381 tagctaaatg aaggcagata accagaacac taaatatcga gaaggtatag ataaatatct
    28441 ttgcaaataa acctgttcgt ttcattttcg ctccaattta taaccaacat tgcgcacagt
    28501 gaggatacaa tccaagtcta gctttttccg caattccttg atataaacat caataacacg
    28561 gtcaaaggga acctcatctg tcgctttcca gacggcatcg ataatctgag atcgagtcaa
    28621 ggcccggcct tcatttttca ctagatagtc cagaatttcc aactctttgg cattgatagg
    28681 cacttcttga cctgcgaggc ttgcactgta gctttcaaag tccaccttgg tatccttgta
    28741 agaaaagatt cgtcctgtat cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa
    28801 aagggagagg gagaaaggtt tttccagata gccatctgcc aaagaggcaa aggcactcat
    28861 cttgtattcc tcatcttgaa aagctgtcaa catcaagaca ggaacctgac tggttttacg
    28921 aatctcagct aggacttcta agccgttgag cttgggcatc tggatatcca gtaaaaccag
    28981 ggccacctca tagctagaaa attgctccag agcttcctga ccgtccgctg cctcaatagt
    29041 ttcatagcca caatccgtca aataatcact gaccccctca cggatcatct cttcatcttc
    29101 tacaattaaa attttcatac tttaactgct ctctattttt tatttttctt agaataaata
    29161 cctaccctat tttctattat agtctcttgc tggccttttg tctgcaagca actgaccact
    29221 agataaaacg ttgtgaaatt cctttctcat aaattccata actttagtat attatattta
    29281 agcactaaag tacaaagaaa gcaactgaaa gcaatgattt tcaccactgc tttcggattt
    29341 attttgaatt gttaaatagc cattcctatc cactattctt gaatagaaac acaagatgca
    29401 atctttattc tagactcatt ttttcaaatt tattcaccat ccagcaagag ctcttttggt
    29461 tgttttctaa ggagattgct tgaagcaagc gccataacga gaaccactag aaccaaggca
    29521 aggacaaaaa tgatgataaa gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc
    29581 ttgctaaagc catctacttc tgcaccacca ccaaggttag aggcttgagc cgccttacta
    29641 gcctgtttgg caacacctga agtcacattg gcaaggacag tgtttccaat tgcacgggca
    29701 gtgtaattag ctaggaagta agcagaaact agagcaggga tagcaatcaa gatagattcg
    29761 gtgatgaatt gacccaagat acttgcctgc ttgaggccga tagagaggag aattcccact
    29821 tccttgcgac gggcgttgat ccaaaggctg agcaagaggg caaggaggag aactgagaag
    29881 ctcaagctac cccagaagag gaggttggcc atcttgtaca taccagagat agattgctca
    29941 agagctgggt agttagagga gctcttgacg agtgtgtagc tcttccagtt gataccactg
    30001 atgccattca actctttcat aacatcatcc aagttcttgt ctgctgttac aaagaaggtt
    30061 gcgtccccat aaatggctgt gtcttctgtg tatccataaa gttttgcagc agtgtgaatg
    30121 tctgtaatag ctgtgttttc gtaaagttct tgtgagtagg ttactgctga cttattatga
    30181 ccatcaaaga gtcccttgat tgtcacttca actgtttcct tggctccttt ttcattatct
    30241 gcatcgtaga tattagagtc cagtttaacc ttgtccccta ctttccagcc gtgtttggct
    30301 gccaagtcct tgtgcaagag gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg
    30361 actagtttat aagaaccaga gacaaacttg tcttctttag aggagtcatt gacacctgta
    30421 atcatcaagc tacttccaaa acgcttggca cgatcagcag tgagattctt cttggtttct
    30481 ggcgtttcaa tcaggtcata tccagtcaaa tctccgatag cgttgatacg tttgacataa
    30541 gactcaatgg ccttgttttc ggtgattttt ttgatgtctt cacccttgat attcccagca
    30601 ccacgaggcg ttccttggtt gacgcgacga ttgatttgca tggagaagct attggtgata
    30661 tttttaaagg tctcctgaga agccttggca gtagctccct tgattgacaa gccgaccaaa
    30721 ctcaagctcg ccatgaggag aataatcagg aagatgacaa tcgatttgaa aaacttcctt
    30781 gtaacatagg caaatgcgtt gtgtaacata gattcccttt ctagattttg ttttaatcat
    30841 tctattaaaa taagctcaaa ttatttacta gtattgcgcg tttcagtcag tttcttatcc
    30901 tttaattcaa gtgtaatatc tgacgcttgt gccacttctt tactgtgagt tacgacaatc
    30961 acacatttac ctgttttctg ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt
    31021 ttaggatcca gatttcctgt tggctcatca gctagaataa ctggagcttc tgagaccaaa
    31081 ctgcgagcaa tggcaacacg ttgctgttga ccacctgata actggagaac attccgcttg
    31141 atctggcttt catccaaacc aagctcaaga agtgtattct tgcttgcctt tttgttgacc
    31201 aatcggatat tttccagcgg agaaagataa tctatcaagt tataattttg aaagaccagg
    31261 gaaatatggt gcatgcgatg gtaagaatag cccttcttac gaatatcctc tccttgaaaa
    31321 aggatagaac cttcaacagg actatctaga ccagcaagta gggacaagag tgtggatttt
    31381 cctgctcctg actccccaat aatactgtaa aattttccgg gttcaaaatt ataattgatc
    31441 tgatatagga ctgcttcagc agtattctta taacggtagg taacatcttg taattgtaat
    31501 aaagtcatga tttctccttc ttaactaata gatgataaaa tttctttcgg tgattttcta
    31561 aataagaata ggaaacaaag ggctacagat aagcaactaa gcagaactag aaaaacatag
    31621 gattctgcaa aagataagat gctagttgat aaactgcttg ctttggctag tgtatcttgt
    31681 aagcttgcct gatctccact tgctagtaga gtttggagta ggtaagttgt gattgcgttt
    31741 cctgcaacaa atgctggaag caaagctcca agagatacca aaactacctc taaacagaat
    31801 tgtaggaaga tcgagctctt gccttttcca agtgcaagta aaatccccac ttcatagacc
    31861 cgttctctca accagagaga caaaaccaga attaaggctc cagctcctgc tatcaacatc
    31921 ccataaagga agatggtcag gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca
    31981 aaagccttgt tttccttttc gacttggtag ccttgatttt ccaaggccaa gttttctacc
    32041 tgcttcatga gtccgtccat ttccttagga ttttctacat agaagcgtgc tgcactgact
    32101 tgagcttcac tattgcccaa aagggtttgg ctactttcat agtctgtaaa gacttgattt
    32161 tcactgaagt cagaagacaa gcctgtgaat ttctcttgtt ttttaccaga aaagatgccg
    32221 ataatctcaa actctactgt ttgtcctttt ccagattcag actgaccagc atccaagcca
    32281 atcttgtcat gaagcgaaag accgttcttc ttagccaatt cttcgtggat aaggattttc
    32341 ttggaatccc ctttttgaag gtgtcgccct tcttttagat tgaaagccga actggtaaag
    32401 gttacatcct tggatgaatc ctcaagagcc gttaagctaa ccaagttatt gtctgcagct
    32461 gataaatcat cacgctccac gctctgctcg ccagtcactg cttccttgtc ttttagtttt
    32521 gcgaccgtct caagttcagg agagacattt tccagcccct taatcttgct tacagatgct
    32581 aggtctgaca acttgaatgt ctgaccattc tctatcttct taatagaaaa agatgtattg
    32641 agtgatttat aaagattgct ttctactgtt ttgttggact tcatcagagt caaacaggct
    32701 gaaattccgg ccaataagac caataaaatc agaaataaaa taaaacttct cagtcgcttt
    32761 ctgctgacat aagcccaaga tctttggatt ggattcattt gtcacctcca tatttgtaag
    32821 actattataa aacccaaata tgaaatgttt atgaaatacg aaaaaaaaat atcgagtagg
    32881 ggataatctc tagcccctct cacaccacc
//
LOCUS       DBEJNA010000028        32788 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEJNA010000028 DBEJNA010000000
VERSION     DBEJNA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.28"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            198..2180
                     /locus_tag="ACL3JB_001410"
     CDS             198..2180
                     /locus_tag="ACL3JB_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0686127.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEEFNKKAQEDLAKHVK"
     gene            2481..7784
                     /locus_tag="ACL3JB_001411"
     CDS             2481..7784
                     /locus_tag="ACL3JB_001411"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0686128.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPVAAKPETPKTVTPEWQTVEKKEQQGTVAIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7951..10110)
                     /gene="pbp1a"
                     /locus_tag="ACL3JB_001412"
     CDS             complement(7951..10110)
                     /gene="pbp1a"
                     /locus_tag="ACL3JB_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0686129.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10107..10703)
                     /gene="recU"
                     /locus_tag="ACL3JB_001413"
     CDS             complement(10107..10703)
                     /gene="recU"
                     /locus_tag="ACL3JB_001413"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0686130.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10769..11296
                     /locus_tag="ACL3JB_001414"
     CDS             10769..11296
                     /locus_tag="ACL3JB_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0686131.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11366..11695
                     /gene="gpsB"
                     /locus_tag="ACL3JB_001415"
     CDS             11366..11695
                     /gene="gpsB"
                     /locus_tag="ACL3JB_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0686132.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDLIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11716..12096
                     /gene="rnpB"
                     /locus_tag="ACL3JB_001416"
     ncRNA           11716..12096
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3JB_001416"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12181..13338
                     /locus_tag="ACL3JB_001417"
     CDS             12181..13338
                     /locus_tag="ACL3JB_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0686133.1"
                     /translation="MKKEFNLIATAAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13351..14721
                     /gene="mapZ"
                     /locus_tag="ACL3JB_001418"
     CDS             13351..14721
                     /gene="mapZ"
                     /locus_tag="ACL3JB_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0686134.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSEGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            14797..16221
                     /gene="gndA"
                     /locus_tag="ACL3JB_001419"
     CDS             14797..16221
                     /gene="gndA"
                     /locus_tag="ACL3JB_001419"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0686135.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16233..16922
                     /locus_tag="ACL3JB_001420"
     CDS             16233..16922
                     /locus_tag="ACL3JB_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0686136.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17020..17985
                     /gene="cbpC"
                     /locus_tag="ACL3JB_001421"
     CDS             17020..17985
                     /gene="cbpC"
                     /locus_tag="ACL3JB_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR0686137.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKLAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPS
                     NGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            18004..19002
                     /gene="cbpJ"
                     /locus_tag="ACL3JB_001422"
     CDS             18004..19002
                     /gene="cbpJ"
                     /locus_tag="ACL3JB_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGR0686138.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNMTVDGYSVNYNGEWVR"
     gene            complement(19120..20352)
                     /locus_tag="ACL3JB_001423"
     CDS             complement(19120..20352)
                     /locus_tag="ACL3JB_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0686139.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEVVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFSLLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(20363..20815)
                     /locus_tag="ACL3JB_001424"
     CDS             complement(20363..20815)
                     /locus_tag="ACL3JB_001424"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686140.1"
                     /translation="MFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILY
                     LCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVI
                     LACSERDDHGLLMFQGDSGKADLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(20883..21271)
                     /locus_tag="ACL3JB_001425"
                     /pseudo
     CDS             complement(20883..21271)
                     /locus_tag="ACL3JB_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
     gene            21882..22211
                     /locus_tag="ACL3JB_001426"
     CDS             21882..22211
                     /locus_tag="ACL3JB_001426"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686141.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            22333..23211
                     /gene="mvk"
                     /locus_tag="ACL3JB_001427"
     CDS             22333..23211
                     /gene="mvk"
                     /locus_tag="ACL3JB_001427"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0686142.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            23193..24146
                     /gene="mvaD"
                     /locus_tag="ACL3JB_001428"
     CDS             23193..24146
                     /gene="mvaD"
                     /locus_tag="ACL3JB_001428"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0686143.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEVVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            24133..25140
                     /locus_tag="ACL3JB_001429"
     CDS             24133..25140
                     /locus_tag="ACL3JB_001429"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0686144.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            25124..26134
                     /gene="fni"
                     /locus_tag="ACL3JB_001430"
     CDS             25124..26134
                     /gene="fni"
                     /locus_tag="ACL3JB_001430"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0686145.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SSQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            26212..26910
                     /gene="liaF"
                     /locus_tag="ACL3JB_001431"
     CDS             26212..26910
                     /gene="liaF"
                     /locus_tag="ACL3JB_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0686146.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            26907..27902
                     /locus_tag="ACL3JB_001432"
     CDS             26907..27902
                     /locus_tag="ACL3JB_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0686147.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            27916..28548
                     /locus_tag="ACL3JB_001433"
     CDS             27916..28548
                     /locus_tag="ACL3JB_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0686148.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            28549..28790
                     /locus_tag="ACL3JB_001434"
                     /pseudo
     CDS             28549..28790
                     /locus_tag="ACL3JB_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            28772..29317
                     /locus_tag="ACL3JB_001435"
                     /pseudo
     CDS             28772..29317
                     /locus_tag="ACL3JB_001435"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            29467..29706
                     /locus_tag="ACL3JB_001436"
     CDS             29467..29706
                     /locus_tag="ACL3JB_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686149.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            29787..30608
                     /gene="cbpG"
                     /locus_tag="ACL3JB_001437"
     CDS             29787..30608
                     /gene="cbpG"
                     /locus_tag="ACL3JB_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGR0686150.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            30627..31649
                     /gene="cbpF"
                     /locus_tag="ACL3JB_001438"
     CDS             30627..31649
                     /gene="cbpF"
                     /locus_tag="ACL3JB_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGR0686151.1"
                     /translation="MKLLKKMMQVVLATFFFGLLGTSTVFADDSVGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEISLRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(31777..32788)
                     /locus_tag="ACL3JB_001439"
                     /pseudo
     CDS             complement(31777..32788)
                     /locus_tag="ACL3JB_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10062 a         5853 c         7395 g         9478 t
ORIGIN      
        1 aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt caatatactt
       61 cgttattgga cggttacgat attcatattt tttgcaaaga tgttgtttga aaaataattt
      121 tcaaaaattc tgaaaattct gttgacaact ttctgaaaag agtctataat ggagagaaag
      181 ttttaaagga gaaaatgatg aaaagttcaa aactacttgc ccttgcgggc gtgacattat
      241 tggcggcgac tactttagct gcatgctctg gatcaggttc aagcgctaaa ggtgagaaga
      301 cattctcata catttatgag acagaccctg ataacctcaa ctatttgaca actgctaagg
      361 ctgcgacagc aaatattacc agtaacgtgg ttgatggttt gctagaaaat gatcgctacg
      421 ggaactttgt gccgtctatg gctgaggatt ggtctgtatc caaggatgga ttgacttaca
      481 cttatactat ccgtaaggat gcaaaatggt atacttctga aggtgaagaa tacgcggcag
      541 tcaaagctca agactttgta acaggactaa aatatgctgc tgataaaaaa tcagatgctc
      601 tttaccttgt tcaagaatca atcaaagggt tggatgccta tgtaaaaggg gaaatcaaag
      661 atttctcaca agtaggaatt aaggctctgg atgaacagac agttcagtac actttgaaca
      721 aaccagaaag cttctggaat tctaagacaa ccatgggtgt gcttgcgcca gttaatgaag
      781 agtttttgaa ttcaaaaggg gatgattttg ccaaagctac ggatccaagt agtctcttgt
      841 ataacggtcc ttatttgttg aaatccattg tgaccaaatc ttctgttgaa tttgcgaaaa
      901 atccgaacta ctgggataag gacaatgtgc atattgacaa agttaaattg tcattctggg
      961 atggtcaaga taccagcaaa cctgcagaaa actttaaaga tggtagcctt acagcagctc
     1021 gtctctatcc aacaagtgca agtttcgcag agcttgagaa gagtatgaag gacaatattg
     1081 tctatactca acaagactct attacgtatc tagttggtac aaatattgac cgtcagtcct
     1141 ataaatacac atctaagacc agcgacgaac aaaaggcatc gactaaaaag gctctcttaa
     1201 acaaggattt ccgtcaggct attgcctttg gttttgatcg tacagcctat gcctctcagt
     1261 tgaatggaca aactggagca agcaaaatct tgcgtaatct ctttgtgcca ccaacatttg
     1321 ttcaagcaga tggtaaaaac tttggcgata tggtcaaaga gaaattggtc acttatgggg
     1381 atgaatggaa ggatgttaat cttgcagatt ctcaggatgg tctttacaat ccagaaaaag
     1441 ccaaggctga atttgctaaa gctaaatcag ccttacaagc agaaggtgtg acattcccaa
     1501 ttcatttgga tatgccagtt gaccaaacag caactacaaa agttcagcgc gtccaatcta
     1561 tgaaacaatc cttggaagca actttaggag ctgataatgt cattattgat atccaacaac
     1621 tacaaaaaga cgaagtaaac aatattacat attttgctga aaatgctgct ggcgaagact
     1681 gggatttatc agataatgtc ggttggggtc cagactttgc cgatccatca acctaccttg
     1741 atatcatcaa accatctgta ggagaaagta ctaaaacata tttagggttt gactcagggg
     1801 aagataatgt agctgctaaa aaagtaggtc tatatgacta cgaaaaattg gttactgagg
     1861 ctggtgatga ggctacagat gttgctaaac gctatgataa atacgctgca gcccaagctt
     1921 ggttgacaga tagtgctttg attattccaa ctacatctcg tacagggcgt ccaatcttgt
     1981 ctaagatggt accatttaca ataccatttg cattgtcagg aaataaaggt acaagtgaac
     2041 caatcttata taaatacttg gaacttcaag acaaggcagt cactgtagat gaataccaaa
     2101 aagctcagga aaaatggatg aaagaaaaag aagagtttaa taaaaaggct caagaagatc
     2161 tcgcaaaaca tgtgaaataa ctgttgcaaa atataagaaa ggatttagta tttctcttga
     2221 atgctgaatc cttttttaca tttgtaaaga aagattctaa atgtactgac ccccaaaagt
     2281 tggagcctct ttttgtcaga atagagaaaa tttttgttaa ttttacttgt ttcctattgc
     2341 tttctcagct attatttgtt atattaaaag cataattatt ttttatttat cagggttaag
     2401 cattgcactt tcagaggaag gagtattttt taaaaagaaa atgtaaacgc ttgctcaaaa
     2461 atgaaaggat ttagaagttt atgaataaag gattatttga aaaacgttgt aaatatagta
     2521 ttcggaaatt ttcattaggt gttgcttctg ttatgattgg agctgcattc tttgggacaa
     2581 gtccggttct tgcagatagc gtgcagtctg gttccacggc gaacttacca gctgatttag
     2641 ctactgctct tgcaacagca aaagagaatg atgggcgtga ttttgaagcg cctaaggtgg
     2701 gagaagacca aggttctcca gaagttacag atggacctaa gacagaagaa gaactattag
     2761 cacttgaaaa agaaaaaccg gctgaagaaa aaccaaaaga ggataaacct gtagctgcta
     2821 aacctgaaac acctaagacg gtaacccctg aatggcaaac ggtagagaaa aaagaacaac
     2881 agggaacagt cgctatccga gaagaaaaag gtgtccgcta caaccaacta tcctcaactg
     2941 ctcaaaatga taacgcaggc aaaccagccc tgtttgaaaa gaagggcttg accgttgatg
     3001 ccaatggaaa tgcaactgtt gatttaacct tcaaagaaga ttctgaaaag ggcaaatcac
     3061 gctttggtgt cttcttgaaa tttaaagata ccaataataa tgtttttgtc ggttatgaca
     3121 aggatggctg gttctgggag tataaatctc caacaactag cacttggtat agaggtagtc
     3181 gtgttgctgc tcctgaaaca ggatcaacaa accgtctctc tatcactctc aagtcagacg
     3241 gtcagctaaa tgccagcaat aacgatgtca atctctttga cacagtgact ctaccagctg
     3301 cggtcaatga ccatcttaaa aatgagaaga agattcttct caaggcgggc tcttatgacg
     3361 atgagcgaac agttgttagc gttaaaacgg ataaccaaga gggggtaaaa acagaggata
     3421 cccctgctga aaaagaaaca ggtccggttg ttgacgatag caaggtgact tatgacacga
     3481 ttcagtctaa ggtcctcaaa gcagtgattg accaagcctt ccctcgtgtc aaggaataca
     3541 gcttgaatgg acatactttg ccaggacagg tgcaacagtt caaccaagtc tttatcaata
     3601 accaccgaat cacccctgaa gtcacttata agaaaatcaa tgagacaaca gcagagtact
     3661 tgatgaagct tcgcgatgat gctcacttaa tcaatgcgga aatgacagta cgcttgcaag
     3721 ttgtggacaa tcaattgcac tttgatgtga ccaagattgt caaccacaat caagtcactc
     3781 caggtcaaaa gattgatgac gaaagaaaac tactttcttc tattagtttc ctcggcaatg
     3841 ctttagtctc tgtttctagt gatcaaactg gtgctaagtt tgatggggca actatgtcaa
     3901 acaatacgca tgtcagtgga gatgatcata tcgatgtaac caatccaatg aaagacctag
     3961 ccaagggtta catgtatgga tttgtttcta cagataagct tgctgctggt gtttggagta
     4021 actctcaaaa cagctatggt ggtggttcga atgactggac tcgtttgaca gcttataaag
     4081 aaacagtcgg aaatgccaac tatgtaggaa tccacagctc tgaatggcaa tgggaaaaag
     4141 cttataaggg cattgttttc ccagaataca cgaaggaact tccgagtgct aaggttgtta
     4201 tcactgaaga tgccaatgca gacaagaaag ttgattggca agatggtgcc attgcttatc
     4261 gtagcattat gaacaaccct caaggttggg aaaaagttaa ggatatcaca gcttaccgta
     4321 tcgcgatgaa ctttggttct caagcacaaa atccattcct tatgaccttg gatggtatca
     4381 agaaaatcaa tctccacaca gatggtcttg ggcaaggtgt tctccttaaa ggatatggta
     4441 gcgaaggcca tgactctggt cacttgaact atgctgatat tggtaagcgt atcggtggtg
     4501 tcgaagactt caagactcta attgagaagg ctaagaaata tggagctcat ctaggtatcc
     4561 acgttaacgc ttcagaaact tatcctgagt ctaaatactt caatgaaaaa attctccgta
     4621 agaatccaga tggaagctat agctatggtt ggaactggct agatcaaggt atcaacattg
     4681 atgctgccta tgacctagct catggtcgtt tggcacgttg ggaagatttg aagaaaaaac
     4741 ttggtgacgg tctcgacttt atctatgtgg acgtttgggg taatggtcaa tcaggtgata
     4801 acggtgcctg ggctacccac gttcttgcta aagaaattaa caaacaaggc tggcgctttg
     4861 cgatcgagtg gggccatggt ggtgagtacg actctacctt ccatcactgg gcagctgact
     4921 tgacctacgg tggctacacc aataaaggta tcaacagtgc catcacccgc tttatccgta
     4981 accaccaaaa agatgcttgg gttggggact acagaagtta tggtggtgca gccaactatc
     5041 cactgctagg tggctacagc atgaaagact ttgaaggctg gcaaggaaga agtgactaca
     5101 atggctacgt gactaacctc tttgctcatg acgtcatgac taagtacttc caacacttca
     5161 ctgtaagtaa atgggaaaat ggtacaccgg tgactatgac cgataacggt agcacctata
     5221 aatggactcc agaaatgcga gtggagttgg tagatgctga caataataaa gtagttgtaa
     5281 ctcgtaagtc aaatgatgtc aatagcccac aatatcgcga acgtacagta acgctcaacg
     5341 gacgtgtcat acaagatggt tcagcttact tgactccttg gaactgggat gcaaatggta
     5401 agaaactttc tactgagaag gaaaagatgt actacttcaa tacgcaggcc ggtacaacaa
     5461 cttggaccct tccaagcgat tgggcaaaga gcaaggttta cctttacaag ctaactgacc
     5521 aaggtaagac agaagagcaa gaactaactg taaaagatgg taaaattacc ctagatcttc
     5581 tagcaaatca accatacgtt ctctatcgtt cgaaacaaac caatcctgaa atgtcatgga
     5641 gtgaaggcat gcacatctat gaccaaggat ttaatagcgg taccttgaaa cattggacca
     5701 tttcaggcga tgcttctaag gcagaaattg tcaagtctca aggggcaaac gatatgcttc
     5761 gtattcaagg aaacaaagaa aaagttagtc tcactcagaa attaactggc ttgaaaccaa
     5821 ataccaagta tgccgtttat gtcggtgtcg ataaccgtag taatgccaag gcgagcatca
     5881 ctgtaaacac tggtgaaaaa gaagtgacta cttataccaa taagtctctc gccctcaact
     5941 atgttaaggc ctacgcccac aatacacgtc gtaacaatgc tacagttgac gatacaagtt
     6001 acttccaaaa catgtacgcc ttctttacaa ctggatcgga cgtatcaaat gttactctga
     6061 cattgagtcg tgaagctggt gatgaagcaa cttactttga tgaaattcgt acctttgaaa
     6121 acaattcaag catgtacgga gacaagcatg atacaggtaa aggcaccttc aagcaagact
     6181 ttgaaaatgt tgctcagggt atcttcccat ttgtagtggg tggtgtcgaa ggtgtcgaag
     6241 acaaccgcac tcacttgtct gaaaaacacg atccatatac acaacgtggt tggaatggta
     6301 agaaagtcga tgatgttatc gaaggaaatt ggtcactcaa gacaaatgga ctagtgagtc
     6361 gtcgtaactt ggtttaccaa accatcccac aaaacttccg ctttgaagct ggtaagacct
     6421 accgtgtaac ctttgaatac gaagcaggtt cagacaatac ctatgctttt gtagtcggta
     6481 agggagaatt ccaatcaggt cgtcgtggta ctcaagcaag caacttggaa atgcatgaat
     6541 tgccaaatac ttggacagat tctaagaaag ccaagaaggt aaccttcctt gtgacaggtg
     6601 cagaaacagg ggatacttgg gtaggtatct actcaactgg caatgcaagt aatactcgta
     6661 gtgattctgg tggaaatgcc aacttccgtg gttataacga cttcatgatg gataatcttc
     6721 aaatcgaaga aattacccta acaggtaaga tgttgacaga aaatgctctg aagaactact
     6781 tgccaacggt tgccatgact aactacacca aagagtctat ggatgctttg aaagaggcgg
     6841 tctttaacct cagtcaggcc gatgatgata tcagtgtgga agaagcgcgt gcagagattg
     6901 ccaagattga agccttgaag aatgctttgg ttcagaagaa aacggctttg gtagcagatg
     6961 actttgcaag tcttacagct cctgctcagg ctcaagaagg tcttgcaaat gcctttgatg
     7021 gaaacttatc tagtttatgg catacatcat ggggcggagg agatgtaggc aagcctgcaa
     7081 ccatggtctt gaaagaacca actgaaataa ctggacttcg ttatgttcca cgtggatcag
     7141 gttcaaatgg taacttgcgt gatgtgaaac ttgttgtgac agatgagtct ggcaaggagc
     7201 atacctttac tgcaactgat tggccagata acaataagtc aaaagatatt gactttggta
     7261 agacaatcaa ggctaagaaa attgtcctta ctggtaccaa gacttacgga gatggtggcg
     7321 ataaatacca atctgcagcg gaactcatct ttactcgtcc acaggtagca gaaacacctc
     7381 ttgacttgtc aggctatgaa gcagctttgg ctaaggctca gaaattaaca gacaaagaca
     7441 atcaagagga agtagctagc gttcaggcaa gcatgaaata tgcgacggat aaccatctct
     7501 tgacggaaag aatggtggaa tactttgcag attatctcaa ccaattaaaa gattctgcta
     7561 cgaaaccaga tgctccaact gtagagaaac ctgagtttaa acttagctct ttagcttccg
     7621 atcaaggtaa gacgccagat tataagcaag aaatagctag accagaaaca cctgaacaaa
     7681 tcttgccagc aacaggtgag agtcaatctg acacagccct cttcctagca ggtgttagcc
     7741 tagccctatc tgctctcttt gtagtaaaaa cgaagaaaga ctagtattta gtaaaacctc
     7801 ttaacaagat tacggaagca gtctctatct tttccaatga ggtttatagt acagaaaaag
     7861 cctgagaaga tgtcttctca ggcttttgtt aagcacataa atacaatagt gctatgacaa
     7921 aatcacctag aaaaatctgg gtgataaatg ttatggttgt gctggttgag gattctgatt
     7981 ttgttgatca ggggttgtat ttgattgttg cgtattattg ttaggattgg tagtcgtact
     8041 attatttgtg cttggagtgg ttgagctaga ctgtgaagtt gaactatctg atgatgagct
     8101 tgaactttca gttgatgggg gttgttgtgg agcaggtgag ttccacgtag aacgagcacc
     8161 atttttaaat acgaattctc catttctgta gagcccctct ggtatattcc aatcttctgg
     8221 attgcttcct tcagacaggt aggtcatcat agagcggtaa actttggcag cgaccgtaag
     8281 gccattgcct acaagtggtg tcagacggtt agaatagcct gtccatacag ccattgaata
     8341 tttacgcgta tagccagcaa atagttcatc aggtgctaca aattgagagg tcttgatgtg
     8401 gttttcaatt tcctcgtctg tatagttaga ggttcctgtt ttaccagcct gaggaagcca
     8461 agcaagatag gcatttcgtc cagttccata agtcaagact gttttcatca tgtcggtcat
     8521 catataggct gtcgtttctt tcatggcacg agttccgaca ttagagaact ctttttcact
     8581 cccatcacta aagacgactt tatggatata cattggttta tagtaagttc caccatttgc
     8641 aaaggcagcg taagcagcag ccatcttttc actacttgct ccatattttt tgtctgattc
     8701 ggttgtgtta cttgaaatgg catttgagta gtgaatactt gggtagtcga ttccgagacc
     8761 atttaggaaa gtcttggcgc ggttgagtcc gaccttgttt agagtttcca cggctgggac
     8821 gtttcgcgat tgttgcaggg cgtattgcaa ggtgatgttg ccaaagtagc ccctatccca
     8881 gttataaaca ggagtatttg tcccagggta attatagggc tcatcgtgaa cgatagtagc
     8941 agttgaatcg tagacaccgt actccaaggc aggagcatag tctgtgatcg gtttcatagt
     9001 tgatccccag tcgcggtttg tttctactgc ttggttaatt ccgaaggaaa cattacttga
     9061 ctgatggcgt gctcctagct gggcaatgac tttaccgtta gaaacatcaa caatggtaga
     9121 agcgacttgc aattcatcgt ctggataggc aacgtattcg tctgtattgt aaatatccca
     9181 cagatgtttt tgagcttctt ggtctacatt tgtgtagaca tccatcccag ttgtgagcag
     9241 gttatagcct gtttcttctt caacttgatt gatgacttcc ttgaggtaat tatccatgta
     9301 agcagggtaa ttacttgctg atttgagact ttgtagtcca tcagtaattg gtgtattgac
     9361 tgctttctca tactgttcag cagagatgta gccttgattt ttcatttcag ataagaccaa
     9421 gtttcggcgg tcttgggctg cttctggatg tgaatagggg tcatattggt ttggtgcctg
     9481 aggcattcca gccagcaagg ctaactgagg taaacttaaa ttattgaggt ctttaccata
     9541 gtagttttga gctgctgtct gcattccata gttcccatta gacatgtaga ccttatttat
     9601 atagtaggtc aagatttctt gcttggttgc tttttgttct aactgaatcg ctaaccaagc
     9661 ttcctgagcc ttacgagaaa tagtctggtc ggaagtcgaa gttgaaaagt aagtcaactt
     9721 aatcaactgt tgggtgagag ttgatccacc ttggagggaa ttgctttgca gattgcgcaa
     9781 gaaagctccc aggatacgga tggtatcaat ccccctgtgg tcgaagaagc gatggtcttc
     9841 gatagaaacg attgccttaa ccaaatctgt gggaatatca ttagcttggg cattgacgcg
     9901 gcgttcagaa cccaagtcag caatgagttg atttttattg tcgtagattt tactagaagt
     9961 tgttgcaact agtttactct cggataggct aggagccttg ctaacgtagt agaaaaaaac
    10021 tcctccgcct aagacaatgg ctgcgataac caagcttaag aagctaatgc tcagatactt
    10081 gattaggcgc agaatcgttg gtttgttcat cttgttttac cacctaataa atgttctttg
    10141 ataacattga gataaggaat ttgagggaag gcaccagcct tgatttcata tccatattct
    10201 cgaatatatt caagtggcat tgatttttgt cccttatctt gatgatagaa gcgaatcaaa
    10261 tcgaatgccg gcaataagta ggtttcttgc tgagaagaaa agtgaagaag gacaaagcag
    10321 attccttgtt gggcaaggac ttgttccata tgctgaatct gatgtggatg aaaatttttc
    10381 atcggaatcg cacgtttttg ttttgtttcc ttgacttcaa agtcgatgta atatccatta
    10441 taaacgccag aatagtccgt cgttgaagct tgtcgaaaat aggcttcaac aatcttggca
    10501 cgacttcgtt gtggatagtc cacttgtacg atttgaatag gagttggttt cttatgtata
    10561 acagccaagc cctgagacaa atagtagtcg ttggtagcat tgatcatctt ttcaaaagac
    10621 attcctcgat ttgcgaaatt tttgggttga gaaagagatg tttgtctttt ttgtgatgaa
    10681 actttatgtg gatagttgac cataattctc cttattggta caataacatc actttattat
    10741 accataattt gcacagaaag ggttaaaaat ggctacagct ttggttttag gctattctgc
    10801 ttttgatttg ggtttatttt ctgataagga tcctcgtctt aaattgatta aaaaagcgat
    10861 acgtaaagat ttagaggcta tggcagcaga tggggtgtct tggcttgtgt ttacaggaag
    10921 tttgggtttt gaatattggg ttttagaggt tgctcaggag atgaaaaccg aatacggttt
    10981 ccagttggcc accatttttg cttttgaaac ccatggggaa aattggaatg aaggcaatca
    11041 gatgaaactg agtcgcttta agcaggtaga ctttgtcaaa tatgcttatc ctcgctatga
    11101 acacaagggg cagttaagag attaccagca gtttttgctg gaaaacacga ctagttccta
    11161 tcttttttat gatgaagaaa atgaaacaaa actagcttat ttttaccaaa agatgaaaaa
    11221 tcaagaggac tattttataa agagattaac atttgatcaa ttaaatgaac ttgctgaaaa
    11281 tttttccgaa aattgaagct ttgaccttga tttttgtttg ccttttttta tataataata
    11341 ctagcaagcg agaatggaga gagacatggc aagtattatt ttttcagcga aagatatttt
    11401 tgaacaagag tttggacgtg aagtccgtgg ctataataaa gtagaagttg acgagttttt
    11461 agacgatctc atcaaggact atgaaaccta tgctgccttg gtcaagtcac ttcgtcagga
    11521 aattgcggat ttgaaggaag aattaactcg taaaccgaaa ccttcaccag ttcaagcaga
    11581 accccttgaa gcggcaatta caagttctat gacgaatttt gatattttga aacgcctgaa
    11641 tagattggaa aaagaagttt ttggtaaaca aattttagat aactcagatt tttaagtagt
    11701 tatttgagat gtgcaatttt tggataatcg cgtgaggaga attgcttctc atgaggaaag
    11761 tccatgctag cacaggctgt gatgcctgta gtgtttgtgc taggcgaaac cataagccta
    11821 gggacgagga atcgttacgg cagttgaaat ggctaagtcc ttggataggc cagagtaggc
    11881 ttgaaagtgc cacagtgacg aagtctttct ggaaacagag agagtggaac gcggtaaacc
    11941 cctcaagcta gcaacccaaa ttttggtcgg ggcatggagt acgcggaaac gaacgtagta
    12001 ttctgactgc tatcagctag agctgttagt ggtagacaga tgattatcga aggaagtggt
    12061 cctagtcact tctggaacaa aacatggctt atagaaaatt gcatataggt tggggctgag
    12121 aaattttctc aacctcattt tttaaagtgg acatatagaa aggtcttgca agactgtaac
    12181 atgaaaaaag aatttaattt aattgcaact gcggcagcag ggcttgaggc tgtcgttggt
    12241 cgtgaagtgc gagagttggg ctacgattgt cagattgaaa atggacgtgt tcgttttcaa
    12301 ggagacgtga gagctattat cgaaaccaac ctttggctgc gggcagcaga tcgtatcaaa
    12361 attatcgtag gaacgttccc tgctaagact tttgaagagc tatttcaggg agttttcgct
    12421 ttagattggg aaaattattt accacttgga gctcggttcc cgatttcaaa agctaaatgt
    12481 gttaagtcca aacttcacaa tgagcccagt gttcaggcta tttctaagaa agctgttgtc
    12541 aagaaattgc agaaacacta tgctcgccca gaaggggttc ctctgatgga gaatggccca
    12601 gagtttaaga ttgaggtctc tattctcaaa gatgtggcaa ctgtcatgat tgatacgacc
    12661 gggtctagcc tctttaaacg tggttatcgt accgaaaaag gtggcgctcc tatcaaggaa
    12721 aatatggcag cagccatttt acaactttct aactggtatc cagacaagcc tttgattgat
    12781 ccgacctgtg gttcggggac tttctgtatt gaggcagtta tgattgctag aaagatggcg
    12841 ccaggtcttc gtcgctcttt tgcatttgag gaatggaact ggatcagcga tcgcttgatt
    12901 caagaagtgc gcacagaagc ggctaaaaaa gtagaccgtg agcttgagct ggatatcatg
    12961 ggctgtgata ttgatgctcg catggtggaa attgctaagg ccaatgctca ggcagctggt
    13021 gttgcaggag acattacttt taagcagatg cgcgtgcagg atttacgttc cgataaaatc
    13081 aatggagtaa tcatttccaa tccgccttat ggtgaacgtt tgtcagatga tgcaggggtg
    13141 accaagctct atgctgagat ggggcaagta tttgcaccgc tgaaaacttg gagcaaattt
    13201 atcctgacta gtgatgaagc ttttgaaagc aagtatggta gccaagcaga taagaagcgt
    13261 aagttataca acggaacctt gaaagtggat ctgtatcaat attttggtca gcgtgtcaaa
    13321 cggcaagagg taaaatagaa agggatactc atgagtaaaa aaagacgaaa tcgtcaaaaa
    13381 aaagaaggtc aagaaccgca atttgatttt gatgaagcaa aagagctaac agttggtcaa
    13441 gctattcgta aaaatgaaga agtggaagca ggagtcttgc ctgaggattc cattttggac
    13501 aagtatgtta agcaacacag agatgaaatt gaggcggata agtttgcgac tcgtcaatac
    13561 aaaaaagagg agttcgttga aactcagagt ctggatgatt taattcaaga gatgcgtgag
    13621 gctgtagaga agtcagaagc ttcttcggag gaagttccat cttctgaaga catcttacta
    13681 cccttgcctc tggacgatga ggagcaaggc ttggatcctc tattgctaga tgatgaaaat
    13741 ccaacagaaa tgactgaaga agtggaagag gagcaaaacc tttctcgtct ggatcaagag
    13801 gactcagaaa agaaaagtaa aaaaggcttt attttgaccg ttttggcgct tgtatcagta
    13861 attatttgtg tcagtgctta ttatgtctac cgtcaagtgg ctcgttcgac caaggaaatt
    13921 gaaacttctc aatcaactac agccaatcaa tcggatgtgg atgattttaa tacactttat
    13981 gacgcctttt acacagatag caataaaacg gctttgaaaa atagccagtt tgataaactg
    14041 aatcaactca agactttact tgataagctg gaaggtagtc gtgaacatac gcttgccaaa
    14101 tctaaatatg atagtctagt aacgcaaatc aaggctattc aagatgtcaa tgctcaattt
    14161 gagaaaccag ctattgtgga tggtgtgttg gatgccaatg ccaaagccaa atcggatgct
    14221 aaatttacgg atattaaaac tggaaatacg gagcttgata aagtgctaga taaggctatc
    14281 agtcttggta agagccagca aacaagtact tctagctcaa gttcaagtca agcaagctca
    14341 aatacgacaa gtgagccaaa accaagtagt tcaaatgaga ctagaagtag tcgcagtgaa
    14401 gtcaatatgg gtctctcgag tgaaggggtt gctgttcaaa gaagtgccag tcgtgttgcc
    14461 tataatcagt ctgctattga tgatagtaat aactctgcct gggattttgc ggatggtgtc
    14521 ttggaacaaa ttctagcgac ttcacgttca cgtggctata tcactggaga ccaatatatc
    14581 cttgaacgtg tcaatatcgt taacggcaat ggttattaca acctctataa gccagatgga
    14641 acctatctct ttacccttaa ctgtaagaca ggctactttg tcggaaatgg cgctggtcat
    14701 gcagatgact tggactacta agcagtcgtt acaaaattct ttcttttcaa aagtaaaaat
    14761 gataaaataa aacaaatgaa acaagaggag tgtcaaatga caaaagctaa ctttggtgtc
    14821 gtaggtatgg ccgtaatggg tcgtaacctt gcccttaata ttgaatcacg tggttacaca
    14881 gttgctatct acaaccgtag taaagaaaaa acggaagatg tgattgcttg ccatcctgaa
    14941 aagaattttg taccaagcta tgacgttgaa agttttgtaa actcaatcga aaaacctcgt
    15001 cgtatcatgc tgatggttca agctggacct ggtacagatg ctactatcca agcccttctt
    15061 ccacaccttg acaagggtga tatcttgatt gacggaggaa acactttcta caaagatacc
    15121 atccgtcgta atgaagaatt ggcaaactca ggtatcaact ttatcggtac tggagtttct
    15181 ggtggtgaaa aaggtgccct tgaaggtcct tctatcatgc ctggtggaca aaaagaggcc
    15241 tacgaattgg tttcggatgt tcttgaagaa atctcagcta aagcaccaga agatggcaaa
    15301 ccatgtgtga cttatatcgg tcctgatgga gctggtcact atgtgaaaat ggttcacaac
    15361 ggtatcgagt acggtgatat gcaattgatc gcagaaagct atgacttgat gcaacacttg
    15421 ctaggccttt ctgcagagga tatggctgaa atctttactg agtggaacaa gggtgaattg
    15481 gatagctact tgatcgaaat cacagctgat atcttgagcc gtaaagacga tgaagaccaa
    15541 gatggaccaa tcgtagacta catccttgat gctgcaggta acaagggaac tggtaaatgg
    15601 acgagccaat catctcttga ccttggtgta ccattgtcac tgattactga gtcagtgttt
    15661 gcacgctaca tttcaactta caaagaagaa cgtgtacatg ctagcaaggt gcttccaaaa
    15721 ccagctgcct tcaactttga aggagacaag gctgaattga ttgaaaaaat ccgtcaagcc
    15781 ctttacttct caaaaatcat ttcatacgca caaggatttg ctcaattgcg tgtagcctct
    15841 aaagaaaaca actggaactt gccatttgca gatatcgcat ctatctggcg tgatggctgt
    15901 atcatccgtt ctcgtttctt gcaaaagatt acagatgctt acaaccgcga tgcagatctt
    15961 gccaaccttc ttttggacga gtacttcttg gatgttactg ctaagtatca acaagcagtg
    16021 cgtgatatcg tagctcttgc ggttcaagct ggtgtgccag tgccaacttt ctcagcagct
    16081 attacttact ttgatagcta ccgttcagct gaccttccgg ctaacttgat ccaagcacaa
    16141 cgtgactact ttggtgctca cacttaccaa cgtaaagaca aagaaggaac cttccactac
    16201 tcttggtatg acgaaaaata agtaggtcag ccatggggaa acggatttta ttacttgaga
    16261 aagaacgaaa tctagctcat tttttaagtt tggaactcca gaaagagcag tatcgggttg
    16321 atctggtaga ggaggggcaa aaagcccttt ccatggctct tcagacagac tatgatttga
    16381 ttttattgaa cgttaatctg ggagatatga tggctcagga ttttgcagaa aaattgagtc
    16441 gaactaaacc tgcctcagtc atcatgattt tagatcattg ggaagacttg caagaagagc
    16501 tggaagttgt tcagcgtttt gcagtttcat acatctataa gccagtcttt atcgaaaatc
    16561 tggtagcgcg tatttcggcg atcttccgag gtcgggactt cattgatcaa cactgcagtc
    16621 tgatgaaagt tccaaggacc taccgcaatc ttaggataga tgttgaacat cacacggttt
    16681 atcgtggtga agagatgatt gctctgaccc gccgtgagta tgaccttttg gcgacactta
    16741 tgggaagcaa gaaagtattg actcgtgagc aactgttgga aagtgtttgg aagtatgaaa
    16801 gtgcgaccga gacaaatatc gtagatgtct atatccgcta tctacggagc aagcttgatg
    16861 ttaaaggtca aaaaagctac attaaaaccg tgcgtggtgt tggttacacc atgcaagaat
    16921 agaaaagcag ttgcagttgt gtaactgctt ttttgaggag tttttatata ttgacatgca
    16981 gtcgggtctt tgctacaatc gttttaggag gatatataga tgaaactttt gaaaaaaatg
    17041 atgcaagttc tactagcagt ctttttcttt ggtttgctag ctacaaatac ggtatttgcg
    17101 aataccacag gtggccgatt tgttgataag gataatagaa aatattatgt aaaagatgat
    17161 cataaagcaa tctattggca taaaatagac ggtaaaactt actattttgg tgatattgga
    17221 gagatggttg tcggttggca atacttagaa attcctggaa caggttatcg tgataattta
    17281 ttcgataacc aaccagttaa tgaaattggc cttcaggaga agtggtacta ttttggacaa
    17341 gatggtgctt tgctagaaca aacagataaa caagtactag aggcaaaaac gtctgaaaat
    17401 acaggaaaag tatacggtga acaatatcct ctatctgctg aaaagagaac ttattatttt
    17461 gataataatt atgctgtaaa gacaggctgg atttatgaag acggcaattg gtattattta
    17521 aataagctag gaaattttgg cgatgattct tacaatccac taccaattgg tgaagttgct
    17581 aagggttgga ctcaagattt tcatgttact attgacattg atagaagcaa acttgctcca
    17641 tggtactacc tagacccaga aactggcatt atgcgaacag gatggcaata tctaggtaat
    17701 aactggtact acctccgttc atcaggagca atggcaacag gttggaaata tgtacgaggc
    17761 aaatggtatt acttagataa taaaaatggt gatatgaaga ctggttggta tcaagatggt
    17821 tcaacttggt actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta
    17881 aatggaaaat ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc
    17941 gatggtaaag tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat
    18001 aaaatgaagc ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg
    18061 ctagctacga atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac
    18121 ggtagaacct attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt
    18181 aagtactatt attttgattc tctatctgga gagatggttg tcggctggca atatatcccg
    18241 tttccatcta aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt
    18301 ccaaagtcag agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg
    18361 aaagaattag agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa
    18421 aattcagaag ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat
    18481 tctttagaga caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa
    18541 attaatggag aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca
    18601 gcttggtact acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt
    18661 aataagtggt actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt
    18721 accacttggt attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt
    18781 gggaacaaat ggtactatct ccgttcctca ggagctatgg caactggttg gtatcaagat
    18841 ggttcaactt ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag
    18901 gtcaatggca actggtacta tgcttatagc tcaggtgctt tggcagtgaa tatgaccgta
    18961 gatggctatt ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat
    19021 tatattagaa cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg
    19081 ggagattaaa agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt
    19141 gactaaccat tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa
    19201 ctgcaccgaa acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag
    19261 aatgtctact gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc
    19321 aaagacagct gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact
    19381 ggtcacgaaa attacgatat aggcttgaca aaggatacta gttattagag ccaataggga
    19441 aatctcacag aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt
    19501 catattgcca aggatagctc cacaagacat gatgatggag agcagggaga agagttgccc
    19561 aatgctcagt tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac
    19621 atccaagatg gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct
    19681 caggagcaca gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt
    19741 atgtgacatt tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc
    19801 caaaaaggca atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac
    19861 attgataagg aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg
    19921 cctgaacccc atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat
    19981 catgtaggca gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat
    20041 gactgaaact aatgaaaagg gcgacaagac gagaaatact gtcaaaatag cgtagagcag
    20101 gattttgatt ttggcaatcc agagtgcgtg tttgactcta ttttcttgaa aatctcctag
    20161 aattccgaga aagagttgcg atagtagggg aaccacctct gaaatggaaa tcagtaaaat
    20221 cgctagcgga gcgaaattgt actgagccac ataattgata atggcaaggt agaaaatact
    20281 gtcgccgaat gatgaaaaac agctgtttag caacaactgt ctatatatgt tgtttgtcca
    20341 aaataatttc atacatttct ccttatgtct gcacatcgaa tgggaattta ttatttaata
    20401 gacaccaata tacccccatg cttcctattc cgaagtcaaa caaatctgct ttaccactat
    20461 ctccttgaaa catcagtaaa ccgtgatcat ctcgttcaga acatgctaaa attacctgtt
    20521 ggattttttt catcagtaat ttgttttgat tgtagacagt ggtttgtagt aagctagtta
    20581 ttccgtggca atatcctgtc atcattttta gatgatggtt aaaaacaaat tcttgatatt
    20641 tactaataat atctttgttt ccgtcacaat cgtacataca aagatataag attattccgg
    20701 aaattccttt gcaccaagaa agttgtaaat ttcctaaatt ttcagtatta gaagtaactt
    20761 tttctaataa tttttttaat tcagtatgga atgtatggag atcattatag aacatagaag
    20821 gttctaagac tttagaatag gcaaataaag cctatgcaat tccacaatat ccatgagcaa
    20881 agctatagtc taaaatgctt tctttggcta tatctctttg taggaaataa tgctaaattt
    20941 cccctatact attgtggatg aaaattttaa gagtattgtc attggtaaat tgatagtatt
    21001 ttattaatga taataggaca ccagattttc ccaatgcaaa gtctatttcc tctagagtat
    21061 cataattctc tattaatttc ttagcggtga cgtttgctaa ttgtagatag tattgatttt
    21121 tactgataga aaataaatgt aggagtaacc atagataacc tgcatcacca aatagcagtg
    21181 agtattgata ttcatatgtg tgtgtcgttc taattgtcac tgccttcttg atgatagaga
    21241 gtattttaga atccagttct gggtggtaca atttatttag aggaaacagt agtccagcta
    21301 ttccgtgttg gaatgataaa ttacttacga aatttccaaa ttctgttgaa gaagtgatcc
    21361 ttccttcaga atttacagtt ttatctagta aaaatcgtag aacactgtta cattctgttt
    21421 tgtaatcata tttatgttcc tctatttttt taattttgac taaattattt gtttgactta
    21481 aatttagtag acattgtaac caaaatagtt gctcatctgt gagctgacct tgagtatgtg
    21541 atagttctag taattgaata ggatccttta gttagattca atcaatctat aacacaacaa
    21601 cataataata cttttaggat aacttatcaa atattatagt aaaatgagat aataacagga
    21661 taaatcgatc aggacagtca aatcgatttc taacaatatt ttagaagtag aggtgtacta
    21721 ttctagtttc aatctactat agtatatatt tttacatctt gaattgtcaa attaagtgca
    21781 taactttccc gtagcatact tcataaggcg ttttccactt aagaaatttt cgtggtcgat
    21841 tatttagaac ctgtattcac aaaaaatgtt aaactagagt tatgacacgc aaagtatatg
    21901 atactgattt aaacgatcaa gaatgggcta agattgaacc ctatttctcc aaacaccgca
    21961 cctataaatg gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt
    22021 gtcaatggcg catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc
    22081 gtcgttctat gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagct
    22141 caggtgcctt ggcagtgaat acgaccgtag atggctattc tgtcaactat aatggcgaat
    22201 gggttcaata atgaaagaag cgattgtgaa tggaaacaat cgcttttttt gtgaaaatat
    22261 aataaaatag ataggaaaga attaatactt gtatgaaaaa taagacgttt tttcgtctag
    22321 taaaaggaaa aaatgacaaa aaaagttggt gtcggtcagg cacatagtaa gataatttta
    22381 ataggggaac atgcggtcgt ttacggttat cctgccattt ccctgcctct tttggaggtg
    22441 gaggtgacct gtaaggtagt tcctgcagag agtccttggc gcctttatga ggaggatacc
    22501 ttgtccatgg cggtttatgc ctcactggag tatttgaata tcacagaagc ctgcattcgt
    22561 tgtgagattg actcggctat ccctgagaaa cgggggatgg gttcgtcagc ggctatcagc
    22621 atagcggcca ttcgtgcagt atttgactac tatcaggctg atctgcctca tgatgtacta
    22681 gaaatcttgg tcaatcgagc tgaaatgatt gcccatatga atcctagtgg tttggatgct
    22741 aagacctgtc ttagtgacca acctattcgc tttatcaaga acgtaggatt tacagaactt
    22801 gagatggatt tatccgccta tttggtgatt gccgatacgg gtgtttatgg tcatactcgt
    22861 gaagccatcc aagtggttca aaataagggc aaggatgccc taccgttttt gcatgccttg
    22921 ggagaattaa cccagcaagc agaagttgcg atttcacaaa aagatgctga aggactggga
    22981 caaatcctca gtcaagcgca tttacattta aaagaaattg gagtcagtag ccctgaggca
    23041 gactttttgg ttgaaacgac tcttagccat ggtgctctgg gtgccaagat gagcggtggt
    23101 gggctaggag gttgtatcat agccttggta accaatttga cacacgcaca agaactagca
    23161 gaaagattag aagagaaagg agctgttcag acatggatag agagcctgta acagtacgtt
    23221 cctacgcaaa tattgctatt atcaaatatt ggggaaagaa aaaagaaaaa gaggtggtgc
    23281 ctgctactag cagtatttct ctaactttgg aaaatatgta tacagagacg accttgtcgc
    23341 ctttaccagc caatgtaaca gctgacgaat tttacatcaa tggtcagcta caaaatgagg
    23401 tcgagcatgc caagatgagt aagattattg accgttatcg tccagctggt gagggctttg
    23461 tccgtatcga tactcaaaac aatatgccta cggcagcggg tctgtcctca agttctagtg
    23521 gtttgtccgc cctggtcaag gcttgtaatg cttatttcaa gcttggattg gatagaagtc
    23581 agttggcaca ggaagccaaa tttgcctcag gttcttcttc tcggagtttt tatggaccac
    23641 taggagcctg ggataaggat agtggagaaa tttaccctgt agagacagac ttgaaactag
    23701 ctatgattat gttggtgcta gaggacaaga aaaaaccaat ctctagccgt gacgggatga
    23761 aactttgtgt ggaaacctcg acgacttttg acgactgggt tcgtcagtct gagaaggact
    23821 atcaggatat gctgatttat ctcaaggaaa atgattttgc caagattgga gaattaacgg
    23881 agaaaaatgc cctggctatg catgctacga caaagactgc tagtccagcc ttttcttatc
    23941 tgacggatgc ctcttatgag gctatggact ttgttcgcca gcttcgtgag aaaggagagg
    24001 cctgctactt taccatggat gctggtccca atgttaaggt cttctgtcag gagaaagact
    24061 tggagcattt atcagaaatt ttcggtcatc gttatcgctt gattgtgtca aaaacaaagg
    24121 atttgagtca agatgattgc tgttaaaact tgcggaaaac tctattgggc aggtgaatat
    24181 gctattttag agccagggca gttagctttg ataaaggata ttcccatcta tatgagggct
    24241 gagattgctt tttctgacag ctaccgtatc tattcagata tgtttgattt cgcagtggac
    24301 ttaaggccta atcctgacta cagcttgatt caagaaacga ttgctttgat gggagacttc
    24361 ctcgctgttc gcggtcagaa tttaagacct ttttccctaa aaatctgtgg caaaatggaa
    24421 cgagaaggga aaaagtttgg tctaggttct agtggcagcg tcgttgtctt ggttgtcaag
    24481 gctttattgg ctctctataa tctttcggtt gatcagaatc tcttgttcaa gctgactagc
    24541 gctgtcttgc tcaagcgagg agacaatggt tccatgggcg accttgcctg tattgtggca
    24601 gaggatttgg ttctctacca gtcatttgat cgccagaagg cggctgcttg gttagaagaa
    24661 gaaaacttgg cgacagttct ggagcgtgat tggggatttt ttatctcaca agtgaaacca
    24721 actttagaat gtgatttctt agtgggatgg accaaggaag tggctgtatc gagtcacatg
    24781 gtccagcaaa tcaagcaaaa tatcaatcaa aattttttaa gttcctcaaa agaaacggtg
    24841 gtttctttgg tcgaagcctt ggagcagggg aaagccgaaa aagttatcga gcaagtagaa
    24901 gtagccagca agcttttaga aggcttgagt acagatattt acacgccttt gcttagacag
    24961 ttgaaagaag ccagtcaaga tttgcaggcc gttgccaaga gtagtggtgc tggtggtggt
    25021 gactgtggca tcgccctgag ttttgatgcg caatcaacca aaaccttaaa aaatcgttgg
    25081 gccgatctgg ggattgagct cttatatcaa gaaaggatag gacatgacga caaatcgtaa
    25141 ggacgagcat attctctatg cccttgagca gaaaagttcc tataatagct ttgatgaggt
    25201 ggagctgatt cattcttcct tgcctcttta caatctggat gaaatcgatc tttcgacaga
    25261 gtttgctggt cgaaagtggg actttccttt ttatatcaat gccatgactg gtggaagtaa
    25321 taagggaaga gaaatcaatc aaaagctggc tcaggtggcg gaatcctgtg gtattttatt
    25381 tgtaacgggt tcttatagcg cagccctcaa aaatccaacg gatgattctt tttctgtcaa
    25441 gtctagtcat cccaatctcc tccttggaac caatattgga ttggacaagc ctgtcgagtt
    25501 aggacttcag actgtagaag agatgaatcc tgtgctattg caagtgcatg tcaatgtcat
    25561 gcaggaatta ctcatgcccg agggagaaag gaagtttaga agctggcaat cgcatctagc
    25621 agattatagc aagcaaattc ccgttcctat tgtcctcaag gaagtgggct ttggaatgga
    25681 tgccaagaca atcgaaagag cctatgaatt cggtgttcgt acagtggacc tatcgggtcg
    25741 tggtggcacc agctttgcct atatcgaaaa ccgtcgtagt agccagcgtg attacctcaa
    25801 tcaatggggt cagtctacca tgcaggccct tctcaatgcc caagaatgga aagataaggt
    25861 cgaactcttg gttagtggag gggttcggaa tccgctggat atgattaagt gcttggtttt
    25921 tggtgctaag gctgtgggat tgtcacgaac cgttctggaa ttggttgaaa cctacacagt
    25981 tgaagaagtg attggcattg tccaaggctg gaaagcagat ctacgcttga ttatgtgttc
    26041 ccttaactgt gccaccatag cagatctaca aaaagtagac tatcttcttt atggaaaatt
    26101 aaaagaagca aatgatcaga tgaaaaaggc gtaaccagcg cctttttttc catcctcaga
    26161 ctgaggtgac ttttttgaat tgtgataaaa tagaagggag aggatgaacc tatgagaaaa
    26221 tttaaaatct ttttatttat cgaagcctgt cttctgacag gagctctgat tttgatggta
    26281 tcagagcatt tttcgcgttt tctgctgata ctattcctct ttttgctttt gattcgctac
    26341 tacactggta aagagggaaa taatcttctt ttagtagcgg taaccattct cttctttttc
    26401 atcgttatgc tcaatccttt tgtgattcta gctatttttg ttgcggttat ctatagcctc
    26461 tttcttcttt acccgatgat gaaccaggaa aaagagcaga ccaatttggt ttttgaagag
    26521 gttgtgacgg ttaagaagga gaaaaatcgt tggtttggaa atcttcatca tttttcaagc
    26581 taccagactt gccaattcga tgatatcaat ctctttcgct tcatgggcaa ggacactatt
    26641 catctggaga gggtcatctt aaccaatcat gacaatgtca ttatcctcag aaagatggta
    26701 ggaacgacca aaatcatcgt acctgtagat gtggaagtca gtctcagcgt taactgtctc
    26761 tatggggatt tgactttttt caaccagccc aagcgagccc tccgcaatga acactatcat
    26821 caagaaacaa aagactatct caagagtaac aagagtgtca agattttctt gaccactatg
    26881 attggtgatg tggaggtggt tagaggatga aaaaacaagc ctatgtcatt attgctctca
    26941 cctccttcct atttgtcttt tttttctccc acagcttgct ggaaatactt gattttgact
    27001 ggtctatctt tttgcacgat gtcgaaaaaa cagaaaaatt tgtcttttta ttgttggttt
    27061 tcagcatgtc catgacctgt ctcttagccc tgttttggcg agggatcgaa gagctttctc
    27121 taagaaaaat gcaggctaat ctcaagcgtt tattggcagg gcaagaagta gttcaggttg
    27181 tagatcaaga tttggatgcc agtttcaagt ccttatcagg taaacttaac cttttgacag
    27241 aggctcttca aaaagctgaa aatcatagcc ttgctcagga agaggaaatc atcgagaagg
    27301 aacggaagcg aattgctcgg gatttgcacg atacagtcag tcaggagttg tttgcggccc
    27361 acatgatttt atcgggtatc agtcagcagg ctttgaaatt ggatagagaa aagatgcaga
    27421 cccagttgca gagtgtcaca gctattttag aaacagccca gaaggatttg cgggttttgc
    27481 tcttgcattt gcgaccagtt gaactggagc agaagagctt gatagaaggg attcaaattc
    27541 tcttaaaaga gcttgaggac aagagtgatc ttagggttag tctcaagcag aatatgacga
    27601 aattgcctaa gaaaatcgag gagcatatct tccgtatcct gcaagagttg attagcaata
    27661 cgctccgcca tgcccaggca tcttgcctag atgtctacct ctatcagaca gatgttgaat
    27721 tgcaactgaa ggtggtggac aatgggattg gtttccagtt agggagctta gacgacttga
    27781 gttatggact gcgaaatatc aaggagcggg ttgaagatat ggcagggacg gttcagttat
    27841 taacagctcc caagcaaggg ctggcagttg atatccgtat tcccctgtta gataaggaat
    27901 gataaaggag taaagatgaa aattttacta gtagatgacc atgaaatggt ccgtttgggt
    27961 ttgaaaagct actttgacct ccaagacgat gtagaagttg tgggtgaggc gtccaacggg
    28021 tctcaaggga ttgacttggc cttggaactg cgtccagatg tcattgtcat ggatattgtc
    28081 atgcctgaga tgaatggaat tgacgcgacc ttagcaatcc ttaaagaatg gcctgaagcc
    28141 aagattttga ttgtgacctc ttatttggac aatgaaaaaa tcatgccagt cttagatgct
    28201 ggtgccaaag gctatatgct caagacttct agtgcagatg aattgcttca tgccgtcagt
    28261 aaggtagctg ctggcgagct ggccattgag caagaggtta gcaagaaggt tgaataccac
    28321 cgcaatcata tggaacttca tgaagaattg actgcgcgtg agcgagatgt tctccaactc
    28381 atcgccaagg gctacgaaaa tcagcgcatc gcagatgacc tctttatctc tctcaagacg
    28441 gtcaagaccc acgtgtccaa cattcttgcc aaacttgaag tcagcgatcg tacccaggcg
    28501 gctgtctacg cctttcagca ccatttggtg gggcatgagg agttttagat gagtttagca
    28561 gatttacttt aggagctaga agcagcaaaa gactctaaaa agcaaggccc atggaagcct
    28621 atatgcgcca tcaattttct tttctaggta ttgcggtgcc tgaaagaaat aaactctata
    28681 aaaatattta ccagaagcga aaaaaacaaa gattatcgat tgggattttg cagacacttg
    28741 ctgggaaaag gagcctagaa aataccaata tgtggctgct aactatttga aagcaatgca
    28801 gtcttatcta aaggaaaccg atttgcctaa gctagagcag ttagtcgtga caaaatcctg
    28861 gtgggacacg gtagatatcc tagatcgagt agtagggagt ttggtgtatg aacaccctga
    28921 actagaagaa ataatcttaa tactcttcga aaatctcttc aaaccacgtc agctctatct
    28981 gcaacctcaa aacagtgttt tgagcaacct gcagctagct tcctagtttg ctctttgatt
    29041 ttcattgagt ataaaatgga gcctatcaga taatatctgg ctgagacgtg tcgctattga
    29101 ccaccagttg ttaataaaag agaagaccaa tactcaatta atggaaaaga ttctacttca
    29161 taacttgaac caaacagaat tttttatcaa taaagccatt ggctggactc tgcgagacta
    29221 ctccaaaacg aatcccactt gggtaacatg ctttattgag aaaaacaagg aaagaatggc
    29281 tgaacttagt atcaaagaag caagtaagta cctctagcgt gattgaaaag cgcagtcatt
    29341 aattgaaaag tttacctgtt tatgtgataa tggagggtat ttaaagaagg tggtagattt
    29401 cttgattcta tagtagatta agaaatttag aatagtacgc tataattaca ttaggaggat
    29461 acaataatga agaaaactgt ttataaaaaa ttgggtattt caattattgc gagtacttta
    29521 ttggctagcc agttatcgac agtatctgct ttgagtgtta tttctagtac aggtgaagaa
    29581 tatgaggtaa gtgagacact agaaaaaggt ccagagtcta atgattcttc attatctgag
    29641 atttcaccaa cgtatggttc atactaccaa aagcaatcag aagtattatc ggtaatgatg
    29701 atttgattaa aattgataat actttacagt atccgtattc gacttcagct atggttttat
    29761 ctaagtatta tggagtagcc gatggaatga atgtagaagg gaggggaagt gcgaatttta
    29821 ttaaagataa tgtgttaatt acagcggctc acaactacta cagacatgac tatgggaaag
    29881 aagcggatga tatttatgtt cttccggctg ttagtccaag tcaagaacta tttggaaaga
    29941 tcaaagtaaa ggaagttcgt tatttgaagg aatttagaaa tttaaattct aagaatgcaa
    30001 gggaatatga cttggcttta ttaattctag aagagcccat tggtgcaaaa ttagggactt
    30061 tgggtcttcc tactagtcaa aaaaatttga caggaataac tgtgactatc acaggctatc
    30121 tatcatataa ttttaaaatt catcaaatgt atacagataa aaaacaagtt ttaagtgatg
    30181 atggcatgtt cttggattac caagttgata ctttagaggg gtctagtgga tctgcagttt
    30241 atgatgctag tcaccgcgta gtaggagtgc atactttagg agatggagct aatcaaatta
    30301 acagtgcagt taaattaaat gaacgaaatt tgccatttat ttattcggtt cttaaaggtt
    30361 actctcttga aggatggaag aaaataaatg gtagttggta ctattataga caacatgata
    30421 aacaaacggg ttggcaggag ataaatgata cttggtatta tttagacagt tccggtaaga
    30481 tgcttacaga ttggcaaaaa gtaaatggaa aatggtatta tctcaattca aatagagcaa
    30541 tggttacagg tagccaaact atcgatggta aagtttataa cttcgcttca tctggtgagt
    30601 ggatttaatg ttggaggata tataaaatga agcttttgaa aaaaatgatg caagtcgtac
    30661 tagccacatt tttcttcggt ttgctaggga ccagtacagt atttgcagat gattctgtag
    30721 gatggcagtt tgtccaagaa aatggtagaa cctactacaa aaagggggat ctaaaagaaa
    30781 cctactggcg agtgattgat ggtaagtact attattttga tcctttatcc ggagagatgg
    30841 ttgtcggctg gcaatatata cctgctccac acaagggggt tacgattggt ccttctccaa
    30901 gaatagagat ttctcttaga ccagattggt tttattttgg tcaagatggt gtattacaag
    30961 aatttgttgg caagcaagtt ttagaagcaa aaactgctac gaataccaac aaacatcatg
    31021 gggaagaata tgatagccca gcagagaaac gagtctatta ttttgaagat cagcgtagtt
    31081 atcatacttt aaaaactggt tggatttatg aagagggtca ttggtattat ttacagaagg
    31141 atggtggctt tgattcgcgc atcaacagat tgacggtggg agagctagca cgtggttggg
    31201 ttaaggatta ccctcttacc tatgatgaag agaagctaaa agcagctcca tggtactacc
    31261 tagatccagc aactggcatt atgcaaacag gttggcaata tctaggtaat aagtggtact
    31321 acctccattc gtcaggagct atggcaactg gctggtataa ggaaggctca acttggtact
    31381 atctagatgc tgaaaatggt gatatgagaa ctggctggca aaaccttggg aacaaatggt
    31441 actatctccg ttcatcagga gctatggcaa ctggttggta tcaggaaggt tcgacttggt
    31501 actatctaaa tgcaagtaat ggagatatga aaacaggctg gttccaagtc aatggtaact
    31561 ggtactatgc ctatgattca ggtgctttag ctgttaatac cacagtaggt ggttactact
    31621 taaactataa tggtgaatgg gttaagtaat gaaggctaat tgtaaactgt gatggatact
    31681 taactttgta taataggtgg ataaaagtct tcacaatcaa aaaacgcata gtatcaaggt
    31741 ttttctgtac tgccccccaa aagttagaca aataatttat ccaaaggatt tagttctgta
    31801 ctgcacagga ctaagtcctt ttagttttac cttaattctc ttgttgttgt aataatcaat
    31861 atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct catagccata
    31921 aaacatttcc gatttcagaa tcccaaagaa ggactccacc atagtgcttc tctgtgaatg
    31981 cctgttccaa cattgttttt acttgttcta agttgggtga agttgaaaga ttataggcga
    32041 taatttcgct gttaaagcca tctaaaactg gtgataagta aagcttttga gtacttgctg
    32101 gaatggaaaa ttcagtcaca tctgtgtagc actgttccat tgttttagag ccttcaaatt
    32161 ggccttgaat gagattctct gccttcttgc caacgtctcc tttatgagaa gaatattttc
    32221 gtttctgtcg cattttagct tgtaaattga gtactttcat caagccttga actcttttat
    32281 gatttaccag ataaccacga tttcttagtt ctaaatgaac ccggcgataa gcataatttc
    32341 ccttgtgttt gataaaaatg gattgaattt cagctttaag ctcttggtcc ttatctggtt
    32401 tgtctagctg tttcaagtga tagtagtagg tcgaacgagc tagtttaatg gcttttagaa
    32461 gaatatctaa cgaaaactca gtcattaatt cttgaataat ttctgtcttt cttctttctc
    32521 tttttcctcc ttcaatcgga gttctcttaa cttttttagg atggcattct ccgctctcag
    32581 gtactctccc tcttgttttc tcaacaatag tatacccgtt tttcctgtat tgtgctagcc
    32641 agttaagaag tatcgtacga cttgggagac agtattcaag agaaactcta tctttagtcc
    32701 agccttcatg tcagacttta tgaatcattt cttgttttaa atcaggagaa tagtaacgat
    32761 tttttccttt tttgacgaac tctattcc
//
LOCUS       DBEJNA010000029        32500 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEJNA010000029 DBEJNA010000000
VERSION     DBEJNA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.29"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            571..1023
                     /locus_tag="ACL3JB_001440"
     CDS             571..1023
                     /locus_tag="ACL3JB_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0686152.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1042..2379
                     /locus_tag="ACL3JB_001441"
     CDS             1042..2379
                     /locus_tag="ACL3JB_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0686153.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2458..3342
                     /locus_tag="ACL3JB_001442"
     CDS             2458..3342
                     /locus_tag="ACL3JB_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686154.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3342..4175
                     /locus_tag="ACL3JB_001443"
     CDS             3342..4175
                     /locus_tag="ACL3JB_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686155.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4370..5473
                     /locus_tag="ACL3JB_001444"
     CDS             4370..5473
                     /locus_tag="ACL3JB_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0686156.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            5647..6345
                     /locus_tag="ACL3JB_001445"
     CDS             5647..6345
                     /locus_tag="ACL3JB_001445"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0686157.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            6364..7881
                     /locus_tag="ACL3JB_001446"
     CDS             6364..7881
                     /locus_tag="ACL3JB_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0686158.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            8006..9334
                     /locus_tag="ACL3JB_001447"
     CDS             8006..9334
                     /locus_tag="ACL3JB_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0686159.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            9586..10452
                     /locus_tag="ACL3JB_001448"
     CDS             9586..10452
                     /locus_tag="ACL3JB_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686160.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            10468..11307
                     /locus_tag="ACL3JB_001449"
     CDS             10468..11307
                     /locus_tag="ACL3JB_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686161.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            11579..12031
                     /locus_tag="ACL3JB_001450"
     CDS             11579..12031
                     /locus_tag="ACL3JB_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0686162.1"
                     /translation="MIFDDLKNITFYKGIYPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            12128..12472
                     /locus_tag="ACL3JB_001451"
     CDS             12128..12472
                     /locus_tag="ACL3JB_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686163.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGAY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            12482..12676
                     /locus_tag="ACL3JB_001452"
     CDS             12482..12676
                     /locus_tag="ACL3JB_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686164.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            12759..13403
                     /locus_tag="ACL3JB_001453"
     CDS             12759..13403
                     /locus_tag="ACL3JB_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0686165.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            13572..14489
                     /locus_tag="ACL3JB_001454"
     CDS             13572..14489
                     /locus_tag="ACL3JB_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0686166.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            14507..15391
                     /locus_tag="ACL3JB_001455"
     CDS             14507..15391
                     /locus_tag="ACL3JB_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0686167.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(15407..16258)
                     /locus_tag="ACL3JB_001456"
     CDS             complement(15407..16258)
                     /locus_tag="ACL3JB_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0686168.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQTSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            16458..18515
                     /gene="pbp2b"
                     /locus_tag="ACL3JB_001457"
     CDS             16458..18515
                     /gene="pbp2b"
                     /locus_tag="ACL3JB_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0686169.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLGSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            18526..19122
                     /gene="recR"
                     /locus_tag="ACL3JB_001458"
     CDS             18526..19122
                     /gene="recR"
                     /locus_tag="ACL3JB_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0686170.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            19298..20341
                     /locus_tag="ACL3JB_001459"
     CDS             19298..20341
                     /locus_tag="ACL3JB_001459"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0686171.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            20425..21798
                     /gene="murF"
                     /locus_tag="ACL3JB_001460"
     CDS             20425..21798
                     /gene="murF"
                     /locus_tag="ACL3JB_001460"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0686172.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            21785..22396
                     /locus_tag="ACL3JB_001461"
     CDS             21785..22396
                     /locus_tag="ACL3JB_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0686173.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            22487..23191
                     /locus_tag="ACL3JB_001462"
     CDS             22487..23191
                     /locus_tag="ACL3JB_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0686174.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            23410..24783
                     /gene="ftsA"
                     /locus_tag="ACL3JB_001463"
     CDS             23410..24783
                     /gene="ftsA"
                     /locus_tag="ACL3JB_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0686175.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKEAFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVELVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            24800..26059
                     /gene="ftsZ"
                     /locus_tag="ACL3JB_001464"
     CDS             24800..26059
                     /gene="ftsZ"
                     /locus_tag="ACL3JB_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0686176.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            26064..26735
                     /locus_tag="ACL3JB_001465"
     CDS             26064..26735
                     /locus_tag="ACL3JB_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0686177.1"
                     /translation="MNVKENTELVFREVAEASLSANRERGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            26745..27284
                     /locus_tag="ACL3JB_001466"
     CDS             26745..27284
                     /locus_tag="ACL3JB_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0686178.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            27284..27547
                     /locus_tag="ACL3JB_001467"
     CDS             27284..27547
                     /locus_tag="ACL3JB_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0686179.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            27544..28329
                     /locus_tag="ACL3JB_001468"
     CDS             27544..28329
                     /locus_tag="ACL3JB_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0686180.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            28338..29126
                     /gene="divIVA"
                     /locus_tag="ACL3JB_001469"
     CDS             28338..29126
                     /gene="divIVA"
                     /locus_tag="ACL3JB_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0686181.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLVQLAQCMKNQK"
     gene            29474..32266
                     /gene="ileS"
                     /locus_tag="ACL3JB_001470"
     CDS             29474..32266
                     /gene="ileS"
                     /locus_tag="ACL3JB_001470"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0686182.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNSPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDKLRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQVVICDHCASI
                     VEENFVEAVAEGFEEK"
BASE COUNT         9904 a         5794 c         7101 g         9701 t
ORIGIN      
        1 ttgaaaacgg taacaaaact aatttagaga atgaaatata gagtatttct ctcttaaaag
       61 tttttggtga aacgagatgt agaaaggaga tttagccaaa gagtctatta gtgctagaat
      121 aatagattag aattatttta gaaaaacgaa gtgagcagct tataaattca agtccccaaa
      181 tagactcata ctagtatctt ttgcaaaaaa taaagggcga cttccttcat gaatatcaat
      241 ttcatctata aggaaggtag ctaattgaac taacttattt attctgtttg tcgctagaaa
      301 aatcagacct ccttgtgaag attgaggaga tacttaatga aaatcaaaga agaaactagc
      361 aagctagtag cagattgccc aaaacaccgc tttgaggttg tagataagac tgacctatat
      421 aatccaaggt gaagcgactg tggtttgaag agattttcaa agagtataga ctagagagta
      481 gtgtttttat gtccttctag tagaaaatgc tagacagaag aatggggaac ttggatagga
      541 aaaatagatt gagaaaggag gttagaagag atgattatta caaaaattag ccgtttagga
      601 acttatgtgg gagtcaatcc acattttgca acattaatag attttctaga aaaaacagga
      661 ctagaaaatt taacagaagg ttcgattgct atcgatggta atcgattgtt tgggaattgc
      721 tttacttatc tagcagatgg tcaagcaggg gatttctttg aaacacacca aaaatatttg
      781 gatattcatt tagttttgga aaacgaagaa gccatggctg ttacatcgcc ggaaaatgta
      841 agcgttaccc aagaatatga tgaagagaaa gatattgaat tatacacagg gaaagtggaa
      901 cagttggttc atttgagagc tggtgaatgc ctcatcactt ttccagaaga tttacatcaa
      961 cccaaggttc gtataaatga tgaacctgtg aaaaaagttg tctttaaagt tgcgatttct
     1021 taatgtagaa agagaagaac gatgaaaaaa atgagaaagt ttttatgtct agctggaatt
     1081 gcgctagcgg ctgttgcctt ggtagcttgt tcaggaaaaa aagaagctac aactagtact
     1141 gaaccaccaa cagaattatc tggtgagatt acaatgtggc actcctttac tcaaggaccc
     1201 cgtttagaaa gtattcaaaa atcagcagat gctttcatgc aaaagcatcc aaaaacgaaa
     1261 atcaagattg aaacattttc ttggaatgac ttctatacta aatggactac aggtttagca
     1321 aatggaaatg tgccagatat cagtacagct cttcctaacc aagtaatgga aatggtcaac
     1381 tcagacgctt tggttccgct aaatgattct atcaagcgta ttggacaaga taaatttaac
     1441 gaaactgcct taaatgaagc aaaaatcgga gatgattact actctgttcc tctttattca
     1501 catgcacaag tcatgtgggt tagaacagat ttgttaaaag aacataatat tgaggttcct
     1561 aaaacttggg atcaactcta tgaagcttct aaaaaattga aagaagctgg agtttatggc
     1621 ttgtctgttc cgtttggaac aaatgactta atggcaacac gtttcttgaa cttctacgta
     1681 cgtagtggtg gaggaagcct cttaacaaaa gatcttaaag cagacttgac aagccaactt
     1741 gctcaagatg gtattaaata ctgggttaaa ttgtataaag aaatctcacc tcaagattct
     1801 ttgaacttta atgtccttca acaagctacc ttgttctatc aaggaaaaac agcatttgac
     1861 tttaactctg gcttccatat cggaggaatt aatgccaaca gtcctcaatt gattgattcg
     1921 attgatgctt atcctattcc aaaaatcaaa gagtctgata aagatcaagg aattgaaacc
     1981 tcaaacattc caatggttgt ttggaaaaat tcaaaacatc cagaagttgc taaagcattc
     2041 ttagaagcac tttataatga agaagactac gttaaattcc ttgattcaac tccagtaggt
     2101 atgttgccaa ctattaaggg gattagcgat tctgcagcct ataaagaaaa tgaaactcgt
     2161 aagaaattta aacatgctga agaagtaatt actgaagctg ttaaaaaagg tactgctatt
     2221 ggttatgaaa atggaccaag tgtacaagct ggtatgttaa ctaaccaaca cattattgaa
     2281 caaatgttcc aagatatcat tacaaatgga acagatccta tgaaagcagc aaaagaagca
     2341 gaaaaacaat taaatgattt atttgaggct gttcagtaga tgtaaaagac tagaaaatag
     2401 gtgggctagt gagctgaaaa gctctagccc aatcttgtaa aagaagggag aaggagaatg
     2461 gttaaagaac gtaatttaac tcgctggata tttgttttgc cagctatgat tatcgtagga
     2521 ttactctttg tttatccgtt tttctcgagt attttttata gctttaccaa taagcatttg
     2581 attatgccta attataaatt tgttggtttg gctaactata aagctgtgct atcagatccc
     2641 aacttcttta atgcgttctt taattcaatt aagtggaccg ttttctcatt agttggtcaa
     2701 gttttagtag ggtttgtatt ggctttagct cttcacagag tacgccactt caagaaatta
     2761 tataggacct tattgattgt tccttgggca tttcctacca tcgttattgc cttttcttgg
     2821 cagtggattc taaacggggt ttatggctac ttacctaatc taatcgtaaa attaggttta
     2881 atggaacata cacctgcatt tttgacagat agtacatggg cattcctatg tttggtgttt
     2941 atcaacattt ggtttggagc accaatgatt atggttaatg tgctttcagc tttgcaaaca
     3001 gtaccagaag aacaatttga ggctgctaag atagatggtg cttcaagttg gcaggtgttc
     3061 aagtttatcg tctttccaca tattaaagtg gttgtaggac ttctagttgt tttgagaact
     3121 gtatggatct ttaataactt tgacattatc tacctcatta ctggtggtgg accagccaat
     3181 gctacaacga cgcttccaat ttttgcttac aacctgggct ggggaactaa attgttgggt
     3241 cgtgcttcag cagttacagt attgctcttt atcttcttgg tggcgatttg ctttatctac
     3301 tttgctatca tcagtaagtg ggaaaaggag ggtagaaaat aatgaagaag aaatccagta
     3361 tttatttaga tattctctca catgtacttt tagttggtgc gaccatcgtt gcagttttcc
     3421 cattggtatg gattatcata tcttctgtca aagggaaagg ggaattaact cagtatccaa
     3481 cacgattttg gcctgaacag tttacattag attatttcac tcatgttatc aacgatttgc
     3541 acttcattga taacattcga aacagtttaa tcattgcctt ggctacaacc cttattgcga
     3601 ttattatttc tgctatggca gcctatggta ttgttcgatt ctttcctaaa ttgggagcaa
     3661 tcatgtcgag actactcgtc attacctaca ttttcccacc aattttgtta gcaattccct
     3721 attcaattgc cattgctaaa gttgggttaa caaatagttt atttggcttg atgatggttt
     3781 atctatcttt tagtgttcca tatgcagttt ggctcttagt tggatttttc caaacagttc
     3841 caattggaat tgaagaagcg gctagaattg atggtgcaaa taaatttgtt acgttttata
     3901 aagttgtgct accgattgta gcaccaggta ttgtagcaac agctatttat acatttatca
     3961 atgcttggaa tgaattcctg tatgccttga ttttgattaa caatacagga aagatgacag
     4021 tagcagtagc ccttcgttca cttaatggtt cagaaatact agactgggga gatatgatgg
     4081 cagcgtctgt tattgtagtt cttccatcaa ttattttctt ctctatcatc caaaataaga
     4141 ttgcaagtgg attatcagaa ggatctgtga agtaatactc aatgaaaatc aaagagcaaa
     4201 ctaggaaact agccgcaggc tgctcaaagt acagctttga ggttgcagat aaaactgacg
     4261 aagtcagtaa ccatacgcac agtaaggaga cgttgacgcg gtttgaagag attttcgaag
     4321 agtataagtt aaaattagaa agtttattca ataataaagg agaaaaaaca tggttaaata
     4381 cggtgttgtt ggagcagggt attttggagc tgaattggct cgctacatgc aaaaaaatga
     4441 tggagcagag attactcttc tctatgatcc agataatgca gaggcgattg cagaagaatt
     4501 gggagcaaaa gtagcaagtt ccttagatga gttggtttct agcgatgaag tagattgtgt
     4561 tatcgtcgca actccaaata atcttcataa ggaaccggtt attaaggctg cacagcatgg
     4621 taaaaatgtt ttctgtgaaa aaccaattgc gctttcttat caagattgtc gcgagatggt
     4681 agatgcgtgt aaagaaaaca atgtaacctt tatggcagga catattatga atttctttaa
     4741 tggtgttcat catgcaaaag aactcatcaa tcaaggagtt atcggagacg ttctatattg
     4801 tcatacagct cgtaatggtt gggaagaaca acaaccgtca gtgtcatgga aaaaaattcg
     4861 tgaaaaatca ggtggtcact tgtatcacca catccatgaa ttggattgcg ttcaattcct
     4921 tatggggggc atgcctgaaa ctgtaaccat gacaggtgga aatgtggccc atgaaggtga
     4981 acatttcggt gatgaagatg atatgatttt tgtcaatatg gaattttcta ataagcgttt
     5041 tgccttgtta gaatggggtt cagcttatcg ttggggtgaa cattatgtct taatccaagg
     5101 aagcaaaggt gccatccgct tagacttatt caactgtaaa ggaactctta agctagatgg
     5161 gcaagaaagc tatttcttga ttcacgaatc gcaagaagaa gatgatgatc ggactcgtat
     5221 ctatcatagt acagagatgg atggagcaat tgcttatggt aaaccaggta aacgtactcc
     5281 attatggcta tcatctgtca ttgataaaga aatgcgctat ctgcatgaga ttatggaagg
     5341 agccccagta tcagaagaat ttgcaaaact tttgacaggt gaagctgccc tagaagcaat
     5401 tgctactgca gatgcttgta cccagtctat gtttgaagat cgcaaagtaa aattgtcaga
     5461 aattgtaaaa taaattttgg tattctccta tttataggtc gacttgctcc tctgaaagta
     5521 cttttagagg agctgtttga ctttgctagt ttttgaaact gaaatctatt atactacaaa
     5581 ctattgaaag cgttttaatt ttaaggtata ataatctcat agaaataaag aaaaggagga
     5641 aagaggatgc cacagattag caaagaagcc ttgattgagc aaatcaaaga tggaatcatc
     5701 gtttcttgtc aggctcttcc tcatgaaccg ctttatacag aagcgggagg ggtgattccc
     5761 ttgctggtca aagcggctga gcaaggtgga gcagtcggta tccgagcaaa cagtgttcgc
     5821 gatatcaagg aaattaagga agtcactaaa cttccaatca ttgggattat caaacgtgat
     5881 tatccacctc aggaaccctt catcacggct actatgaaag aagttgatga attggcagaa
     5941 ctggacatcg aggtgattgc tctggattgt accaagcgtg aacgctacga tggtttggaa
     6001 attcaagagt tcattcgtca ggttaaggag aaatatccta atcagctttt gatggctgat
     6061 actagtatct tcgaagaagg gctagcagct gtagaagcag gaattgactt tgtcggaaca
     6121 accttatcag gctacacatc ctacagtcca aaagtagacg gtccagattt tgaattgatt
     6181 aagaaactct gtgatgccgg tgtagatgtc attgcagaag gaaaaattca tacaccagaa
     6241 caagccaaac aaatccttga atatggagtg cgaggcatcg ttgttggtgg cgccattact
     6301 agaccaaaag agattacaga acgcttcgtt gctagtctta aataagatgt gagagggagt
     6361 tttatgttta aagttttaca aaaagttgga aaagctttta tgttacctat agctatactt
     6421 cctgcagcag gtctactttt ggggattggt ggtgcacttt caaacccaac cacgatagca
     6481 acttatccaa tactagacaa tagtattttt caatcaatat tccaagtaat gagctctgca
     6541 ggagaggttg tattcagtaa tttgtcacta cttctctgtg tgggattatg tattggctta
     6601 gcgaaacgag ataaaggaac cgctgcgtta gcaggagtaa ctggttactt agttatgact
     6661 gcaacgatca aagctttggt aaaacttttt atggcagaag gatctgcaat tgatactgga
     6721 gttattggag cattagttgt cggaatagtt gccgtatatt tgcacaaccg atataacaat
     6781 attcaattac cttccgcttt aggattcttt ggaggttcac gcttcgttcc tattgttaca
     6841 tcgttctctt ctatcttgat tggctttgtc ttctttgtta tttggccacc tttccaacaa
     6901 cttcttgttt ctacaggtgg atatatttct caggcgggtc caattggaac ttttctatat
     6961 ggatttttaa tgagactttc tggagcagta ggcttacatc atataattta ccctatgttt
     7021 tggtatactg aacttggtgg tgttgaaact gttgcaggac aaacagtggt tggagctcaa
     7081 aaaatatttt ttgctcaatt agccgatttg gcccattctg gattatttac agaaggaaca
     7141 aggttttttg caggtcgttt ctcaacaatg atgttcggtt taccggctgc ctgtttagcg
     7201 atgtaccata gtgttcctaa aaatcgtcgt aaaaaatacg cgggtttgtt ttttggagtt
     7261 gctttaacat cttttattac cggtattaca gaaccaattg aatttatgtt tctattcgtc
     7321 agtccggttc tatatgttgt tcacgcattc cttgatggtg ttagcttctt tattgcagac
     7381 gtcttaaata tttcaatagg aaacacattt tcaggaggtg taatcgattt cactttattt
     7441 ggaattttgc aggggaacgc taagacgaat tgggttcttc agattccatt tggacttatt
     7501 tggagtgttt tgtattatat tatttttaga tggttcatta ctcaattcaa cgttctaacg
     7561 ccaggacgag gagaagaagt agattctaaa gaaatttctg aatccgcaga ttcaacttca
     7621 aatactgcag attatttaaa acaggatagc ctacaaatta tcagagcctt gggtggatca
     7681 aataatatag aagatgtaga tgcttgtgtg acacgtttac gtgtagctgt aaaagaagtt
     7741 aatcaagttg ataaagcact tttaaaacaa attggtgcag ttgatgtctt agaagtgaag
     7801 ggtggcattc aagcaatata tggagcaaaa gcaatcttat ataaaaatag tattaatgaa
     7861 attttaggtg tagatgatta agtacttact gacttaataa aaaacagagg agagtgatgg
     7921 atgagtagga tgaaatgaaa tcgcatacaa gaaataaaga actcattatc caagttggat
     7981 acgcttatta cataggagaa tacaaatgaa atttagaaaa ttagcttgta cagtacttgc
     8041 gggtgctgcg gttcttggtc ttgctgcttg tggcaattct ggcggaagta aagatgctgc
     8101 caaatcaggt ggtgacggtg ccaaaacaga aatcacttgg tgggcattcc cagtatttac
     8161 ccaagaaaaa actggtgacg gtgttggaac ttatgaaaaa tcaatcatcg aagcgtttga
     8221 aaaagcaaac ccagatataa aagtgaaatt ggaaaccatc gacttcaagt caggtcctga
     8281 aaaaatcaca acagccatcg aagcaggaac agctccagac gtactctttg atgcaccagg
     8341 acgtatcatc caatacggta aaaacggtaa attggctgag ttgaacgacc tcttcacaga
     8401 tgaatttgtt aaagatgtca acaatgaaaa catcgtacaa gcaagtaaag ctggagacaa
     8461 ggcttatatg tatccgatta gttctgcccc attctacatg gcaatgaaca agaaaatgtt
     8521 agaagatgct ggagtagcaa accttgtaaa agaaggttgg acaactgatg attttgaaaa
     8581 agtattgaaa gcacttaaag acaagggtta cacaccaggt tcattgttca gttctggtca
     8641 agggggagac caaggaacac gtgcctttat ctctaacctt tatagcggtt ctgtaacaga
     8701 tgaaaaagtt agcaaatata caactgatga tcctaaattc gtcaaaggtc ttgaaaaagc
     8761 aactagctgg attaaagaca atttgatcaa taatggttca caatttgacg gtggggcaga
     8821 tatccaaaac tttgccaacg gtcaaacatc ttacacaatc ctttgggcac cagctcaaaa
     8881 tggtatccaa gctaaacttt tagaagcaag taaggtagaa gtggtagaag taccattccc
     8941 atcagacgaa ggtaagccag ctcttgaata ccttgtaaac ggatttgcag tattcaacaa
     9001 taaagacgac aagaaagtcg ctgcatctaa gaaattcatc cagtttatcg cagatgacaa
     9061 agagtgggga cctaaagacg tagttcgtac aggtgctttc ccagtccgta cttcatttgg
     9121 aaaactttat gaagacaaac gcatggaaac aatcagcggc tggactcaat actactcacc
     9181 atactacaac actattgatg gttttgctga aatgagaaca ctttggttcc caatgttgca
     9241 atctgtatca aatggtgacg aaaaaccagc ggatgctttg aaagccttca ctgaaaaagc
     9301 aaacgaaaca atcaaaaaag ctatgaaaca atagtcctta gttattctat aaaaagtagt
     9361 tttttaaaga acctaagagt gtataccccc ttttccctct acacagatag tgtaagaaaa
     9421 gggggctttt gtttaaaatg taagaaactg tcacgaaatt aaaatgaagt tcttacataa
     9481 gcgaatcata aaaaatttca ttttgatttt aaaacagttc aagaaagtca aaaaattatt
     9541 ctatttgaaa gagaggtgcc gactgtgaaa gtcaataaaa tccgtatgcg ggaaacagtg
     9601 atttcctacg ctttcctagc accagtatta ttcttctttg tcatctttgt gttggctccg
     9661 atggtgatgg gcttcattac aagtttcttt aactactcaa tgactaaatt tgagtttgta
     9721 ggcttggata actatatccg tatgtttaaa gatcctgtct ttacaaaatc tctgattaac
     9781 acagttattt tggttattgg atctgtacca gttgttgttc tattctcact ctttgtagca
     9841 tctcagacct atcatcaaaa tgtcattgcc agatccttct accgtttcgt cttcttcctt
     9901 cctgttgtaa cgggtagtgt tgccgtgaca gttgtttgga aatggattta tgacccgcta
     9961 tcagggattc taaactttgt ccttaagtca agccacatca tcagccaaaa catttcttgg
    10021 ttgggagata aaaactgggc attgatggcg attatgatta ttctcttgac cacttcagtt
    10081 ggtcagccca tcatccttta tatcgctgcc atggggaata ttgacaattc actggttgaa
    10141 gcggcgcgtg ttgatggtgc aactgagttt caagtttttt ggaagattaa atggccaagc
    10201 cttcttccaa caactcttta tattgcaatc atcacaacaa ttaactcatt ccagtgtttc
    10261 gccttgattc agcttttgac atctggtggt ccaaactact caacaagtac cttgatgtac
    10321 tacctttacg aaaaagcctt ccaattgaca gaatacggct atgccaacac aattggtgtc
    10381 ttcttggcag tcatgattgc tatcgtaagc tttgttcaat ttaaagtact tggaaacgac
    10441 gtagaatact aaagaaagga gacagctatg caatctacag aaaaaaaacc attaacagcc
    10501 tttactgtta tttcaacaat cattttgctc ttgttgactg tgctgttcat ctttccattc
    10561 tactggattt tgacaggggc attcaaatca caacctgata caattgttat tcctcctcag
    10621 tggttcccta aaatgccaac catggaaaac ttccaacaac tcatggtgca gaaccctgcc
    10681 ttgcaatgga tgtggaactc agtatttatc tcattggtaa ccatgttctt agtttgtgca
    10741 acctcatctc tagcaggtta tgtattggct aaaaaacgtt tctatggtca acgcattcta
    10801 tttgctatct ttatcgctgc tatggcgctt ccaaaacaag ttgtccttgt accattggta
    10861 cgtatcgtca acttcatggg aatccacgat actctctggg cagttatctt gcctttgatt
    10921 ggatggccat tcggtgtctt cctcatgaaa caatttagtg aaaatattcc tacagagttg
    10981 cttgaatcag ctaaaatcga cggttgtggt gagattcgta ccttctggag tgtagccttc
    11041 ccgattgtga aaccagggtt tgcagccctt gcaatcttta ccttcatcaa tacttggaat
    11101 gactacttca tgcaattggt aatgttgact tcacgtaaca atttgaccat ctcacttggg
    11161 gttgcgacca tgcaggctga aatggcaacc aactatggtt tgattatggc aggagctgcc
    11221 cttgctgctg ttccaatcgt cacagtcttc cttgtcttcc aaaaatcctt cacacagggt
    11281 attactatgg gagcggtcaa aggataatac tctgcgaaaa tctcttcaaa ctacgtcagc
    11341 ttcaccttgc catacttaag tattgcctgc ggttagcttc ctagtttgtt cttcaatttt
    11401 cattgagtat aggaaaatca atctatcaag atacagaagt atattttata gatttagaga
    11461 atatagaggt tataagtgtc tacaaaatgg agggtatgca gttactttat gaagttttgt
    11521 cagacactta tcaacttaag aatggtttta gttaactatc agaaacgaag gaaagagtat
    11581 gatttttgac gatttgaaaa acatcacctt ttacaaaggg atttatccta atttagacaa
    11641 ggctatcgac tatctctacc aacatcgtaa ggattctttc gaattaggaa agtatgatat
    11701 tgatggagat aaagtctttc tagttgttca ggaaaatgtc ctcaatcaag ctgaaaatga
    11761 tcaatttgag tatcataaga actatgcaga tttgcatttg ctgatagaag ggcatgaata
    11821 ttcgagctac ggttcacgta tcaaagacga ggcagtagca ttcgacgaag cgagtgacat
    11881 tggctttgtt cattgttatg aacactaccc actcttattg ggttatcaca attttgcgat
    11941 tttcttccca ggtgagccac atcagccaaa tggttatgca ggcatggaag aaaaggttcg
    12001 aaaatatctc tttaaaatct tgattgatta aaaataggat gaattgtttt tttgtaaagc
    12061 tttgataata ctctaccatg aaattgatct ttgtgaggta gagaaatgag aataaaatat
    12121 ttaaaaattg gtatcttcta agtatgctgc aagagctagt ttcttggatg gacagggaat
    12181 tacagttgat gagatggctt ggataattag gggcattgtg aatgcattga ttggtagata
    12241 cataaaatta ggtgcttatg cggctaagta tggtattagt atggcacgct cgatcttaag
    12301 tagggcagct gcaactgcgg cagcaagagt aggattattg accaagattt ttggatggat
    12361 tttacgaata gctgtgctcg cagctgatgt atatggtaat tttgccaaca atattgctgc
    12421 agcttgggat gcatatgata aaattcctaa caatggtcgt ataaactttt aaaatgcgag
    12481 aatgaaagca ctttgtattt ttttattgaa tatgttagct tggacagtgc ttgcaatgat
    12541 aattcgtgga gggctagatg gatttaatga gcatacttgg agtactattt taattgcttc
    12601 gctgtccggg atatatatag attatatgtc catagataaa agtagaaaaa agtccaaaag
    12661 aaaaaagaaa aaatagattt gttcatggta gggacttatg aaagttttac tgacaaaaaa
    12721 gaaaacagtt tacaaagaaa aatgatggag gagcaaacat ggcacaaaaa ggagtaagcc
    12781 ttatcaaggc agcatttgat acagataact ttctcatgcg ttttagtgag aaagtcttgg
    12841 acatcgtgac agccaatctt ctttttgtcg tctcttgttt gcccatcgtg acgattggag
    12901 tggctaaaat cagcctctac gagaccatgt tcgaagttaa gaagagcaga cgggtgcctg
    12961 tttttaaaat ctatctaaga tctttcaagc aaaatctgaa actaggtctt cagctgggtt
    13021 taatggagtt aggaattgtg tttcttaccc tttcagatct ctatcttttc tggggtcaaa
    13081 cagctctgcc cttccaattg ctgaaagcca tttgtttagg tattctgatt tttcttacta
    13141 tcgtgatgct ggctagttac cctatcgcgg cacgttatga cctatcttgg aaagaaattc
    13201 ttcaaaaagg attgatgttg gctagtttta actttccttg gttcttcctc atgttagcca
    13261 ttcttgtcct cattgtgatg gttctttatc tgtccgcctt cagtctactc ttaggtggct
    13321 cagtcttcct actttttggg tttggactat tggtctttat ccagactgga ttgatggaga
    13381 aaattttcgc aaaataccaa taggagcttt atttctgaaa ctactttcaa aggctccaaa
    13441 cgctattcta taagcgagaa actaaaatct aagtgtctat aagatattga aagccttttc
    13501 ggtaaagtgt atactaaaga agtaaagaaa aatctgcttt agcagaaaat aaaaataata
    13561 ggagaaaatc tatgtcagat ttgaaaaaat acgaaggtgt cattccagcc ttctacgcat
    13621 gttatgatga tcaaggagaa gtaagcccag aacgtacgcg tgccttggtt caatacttca
    13681 ttgataaagg tgttcaaggt ctttatgtca atggttcttc tggtgaatgt atctaccaaa
    13741 gcgttgaaga tcgcaagttg attttggaag aagtcatggc ggtagccaaa ggtaaattga
    13801 ccattattgc ccatgttgct tgcaataata ctaaagatag tatggaactt gctcgccatg
    13861 ctgaaagctt gggagtagat gctattgcaa cgattccacc aatttacttc cgcttgccag
    13921 aatactcagt tgctaaatac tggaacgata ttagttctgc agctccaaat acagactacg
    13981 tgatttataa cattcctcaa ttggcagggg ttgctttgac tccaagcctt tacactgaaa
    14041 tgttgaaaaa tcctcgtgtt atcggtgtga agaactcttc tatgccagtt caagatatcc
    14101 aaacctttgt gagccttggt ggggaagacc atatcgtctt taacggtcca gatgaacagt
    14161 tcctaggtgg ccgcctcatg ggtgccaaag ctggtatcgg tggtacttat ggtgctatgc
    14221 cagaactctt cttgaaactc aatcagttga ttgcggataa ggacctagaa acagcgcgtg
    14281 aattgcagta tgctatcaac gctatcattg gtaaattgac tgctacacat ggaaatatgt
    14341 acggtgtcat caaagaagtt ttgaagatca atgaaggctt gaatattggt tctgttcgtt
    14401 caccattgac accagtgact gaagaagatc gtccagttgt agaagcggct gctgccttga
    14461 ttcgtgaaac caaggagcgc ttcctctaat ctaaaaggag gtatttatga catactacgt
    14521 tgcaattgat atcggtggaa ccaacatcaa gtatggtttg gttgatcaag aggggcaact
    14581 tcttgaatcg catgaaatgc caactgaggc gcataagggt ggacctcata tcttacaaaa
    14641 gaccaaagat atcgtagcta gttatttaga aaaaggccca gtagcaggtg ttgccatatc
    14701 ttctgctggg atggtggatc cggataaggg tgagattttc tatgctgggc cgcaaatccc
    14761 taactacgca ggcacccagt tcaaaaagga aatcgaagaa agctttacta ttccttgtga
    14821 gattgaaaat gatgtcaact gtgcaggtct tgctgaggca gtatctggtt caggcaaggg
    14881 agcaagtgtg acactttgct tgaccattgg aacaggtatc ggtggttgct tgattatgga
    14941 taggaaagtc ttccatggtt ttagcaattc agcctgtgaa gtcgggtata tgcatatgca
    15001 ggatggagct tttcaagact tggcttctac aacagcttta gtgaaatatg tagctgaagc
    15061 ccatggagaa gatgttgatc agtggaatgg ccgtagaatt ttcaaagaag ccactgaagg
    15121 aaacaaaatc tgcatggaag gtattgaccg tatggttgac tatctaggaa aaggtctggc
    15181 aaatatttgc tacgttgcca atccagaagt ggttattctt ggtggtggta tcatggggca
    15241 agaggctatc ctcaaaccta agatccgcac agccttgaaa gaggctttgg taccaagttt
    15301 agcagaaaaa acacgattag aatttgccca tcaccaaaat acagcaggga tgttgggtgc
    15361 atattatcat tttaagacaa aacaatccta gtttggctca gccaaactag gattttctta
    15421 cacgtttttg tctacgatag ccgttgagtt ttttattttc ccagtagcta ttaaagattt
    15481 tttccttgct ttcgcgattg atttccaaaa agtaggcata aatcaaatcg ataaagaaga
    15541 gcataggaag ttgagcggat attcgttgga tataggaggt ttggctatgg gtggctacaa
    15601 gaacagtctc tgtataggtc tggctatctt tattgggaac acttgtaaag agtacagtct
    15661 ttgcccccat ctccttggca tctaatagac tatctaaaat agaaggagtt gagcctgaaa
    15721 gtgagaaacc cagtactaga caattttcat ccatgatgct ggttgtccag gcaaagccgt
    15781 cttggtctgt caaagcttcg cagaccacac ctagtcgcat aaaacgtaat ttcatttcac
    15841 gggcgacgag gccagaactc cctgttccaa agaagtagat acgctcagca tcttcgatta
    15901 gctgggcaat tcgctctagt tggatttcgt caatcaagtc ttgtgtttgt tccctcatat
    15961 tgctataact tctgaggact cgtttggtca gtggactatg cttggagact tggttggctt
    16021 gattttctgc ctgatgttgg tattggaaaa taaattctcg gtagccagta aagccacact
    16081 ttttagcaaa gcgggtcaaa gcagcttgag aaatatgtaa tttttgggtg acttgttgag
    16141 aagataaatc atctgtaatc gtttcagctt gcaaaaaata gcgagcgatt tcttgctcta
    16201 ggtctgtcat ttcttcaaaa tgtgaatcaa tgatagttgc gatatctggt ttgtccatag
    16261 ggaaagctcc tttacatgag tcatactgga agactagatc agggaatagt cacacttcat
    16321 tataacacat aatataagga tagataaata aaaacacatc tctgttttaa aaacgaaaaa
    16381 atcgaaaaag cttctttctt ttccataatt ttctactcaa attgtggtac aattaagagt
    16441 aagattttaa gttagaaatg agactgattt gtatgagaaa atttaacagc cattcgattc
    16501 cgattcggct taatttattg ttttcaatcg tcattttact ctttatgacc attattggtc
    16561 gtttgttgta tatgcaggtt ttgaacaagg atttttacga aaaaaagcta gcttcagcta
    16621 gtcagaccaa gattacaagc agttcagccc gtggggaaat ttatgatgct agtggaaaac
    16681 ctttggtaga aaatacgtta aagcaggttg tttcctttac gcgtagcaat aaaatgacgg
    16741 ctacagactt aaaagaaaca gctaaaaagt tactgactta tgtgagcatc agttctccaa
    16801 atttgacaga acgccagctg gcggattact atttggctga tcctgaaatc tataaaaaaa
    16861 cagtggaagc tctcccaagc gagaaacgct tgggttcaga tggcaatcgt ctatccgaat
    16921 cagaactgta taacaatgcg gtcgatagtg tccaaacaag tcaactaaac tatacagagg
    16981 atgaaaagaa agaaatctat ctttttagtc agttaaatgc tgttggaaac tttgcgacag
    17041 gaaccattgc gacagatcct ctaaatgatt ctcaggtggc tgttattgcc tctatttcaa
    17101 aggagatgcc tggcattagt atttctactt cttgggatag aaaggttttg gaaacttccc
    17161 tttcttctat agttgggagt gtatccagtg aaaaagctgg tctcccagcg gaagaagcag
    17221 aagcctatct taaaaaaggc tattctctaa atgatcgtgt aggaacctcc tatttggaaa
    17281 agcaatatga agagacctta caaggaaaac gctcggtaaa agaaatccat ctggataaat
    17341 atggcaatat ggaaagcgtg gatacaattg aggaaggtag taagggaaac aatatcaaac
    17401 tgaccattga tttggcattc caagatagcg tggatgcttt actgaaaagt tatttcaatt
    17461 ccgagctaga aaatggtgga gccaagtatt ctgaaggtgt ctatgcagtc gcccttaacc
    17521 caaaaacagg tgcggttttg tctatgtcag ggattaaaca tgacttgaaa acgggagagt
    17581 tgacgcctga ttccttggga acggtaacca atgtctttgt tccaggttcg gttgtcaagg
    17641 cggcgaccat cagctcaggt tgggaaaatg gagtcttgtc aggaaaccag accttgacag
    17701 accagtccat tgtcttccaa ggttcagctc ccatcaattc ttggtatact caggcttacg
    17761 gttcattccc tatcacagcg gtccaagctc tggagtattc atctaatacc tatatggtcc
    17821 aaacagcctt aggtcttatg gggcaaacct atcaacccaa tatgtttgtc ggcaccagca
    17881 atctagagtc tgctatggag aaactgcgtt caacctttgg cgaatatggc ttgggtactg
    17941 cgacaggaat tgacctacca gatgaatcta ctggatttgt tcccaaagag tatagctttg
    18001 ctaattacat tactaatgcc tttgggcagt ttgataacta tacgccgatg cagttggctc
    18061 agtatgtagc aactattgca aataatggtg ttcgtgtggc tcctcgtatt gttgaaggca
    18121 tttatggtaa taatgataag ggaggactgg gtgacttgat tcagcaactg caaccgacag
    18181 agataaataa ggtcaatata tccgactccg atatgagcat cttgcaccaa ggtttttatc
    18241 aggttgccca tggtactagt ggattgacaa ctggacgtgc cttttcaaat ggtgccttgg
    18301 tatccattag cggaaaaaca ggtacagccg aaagctatgt ggcagatggt cagcaagcaa
    18361 ccaataccaa tgcggtggcc tatgccccat ctgataatcc ccaaatcgct gtcgcagtgg
    18421 tctttcctca taataccaat ctaacaaatg gtgtaggacc ttccattgcg cgtgacatta
    18481 tcaatctgta tcaaaaatac catccaatga actagaaagg aaattatgct ttatccaaca
    18541 cctattgcca agttgattga cagttattct aagttaccag gtatcgggat taagacggct
    18601 acgcgtctgg ccttttatac gattgggatg tctgctgatg atgtcaatga atttgcaaaa
    18661 aatctccttt ctgctaagag agaattgaca tattgttcta tttgtggacg tttgacagac
    18721 gacgatcctt gttctatctg tactgattcg actcgtgacc agacaacaat tttagttctt
    18781 gaggatagta gagatgtggc agccatggaa aatatccaag aataccatgg actctatcat
    18841 gtcctgcatg gcctcatttc tcctatgaat ggtatcagtc cggacgatat caatcttaag
    18901 agccttatga ctcgtcttat ggatagtgag gtttcagaag tgattgtggc gactaatgct
    18961 acagcggatg gtgaagcgac ctccatgtat ctttcacgtt tgctcaagcc ggctggtatc
    19021 aaggttacgc gtctagcacg aggtctcgct gtgggagcgg acattgagta tgcggacgaa
    19081 gtgacactct tacgagcgat tgaaaatcgg acagagttgt aagtgtaggc aaatttacga
    19141 actccattca tttataaaaa atcaaagagg ctgaaaatcg ttcctatcgg cctctttttg
    19201 tatagtgtga tgagtagaat caggttcaag ttttaaaaaa ccaagcaaat atgatatact
    19261 aaagagcgag tattctagta gaattaggac aaataatatg aaacaaacga ttattctttt
    19321 atatggtgga cggagtgcgg aacgcgaagt ctctgtcctt tcagctgaga gtgtcatgcg
    19381 tgcggtcaat tacgaccgtt tcacagtcaa gactttcttt atcagtcagt caggtgactc
    19441 tatcaaaacg caggaattta gtcatgctcc ggggcaagaa gaccgtctca tgaccaatga
    19501 aaccattgat tgggataaga aagttgcacc aagtgctatc tacgaagaag gtgcagtggt
    19561 ctttccagtc cttcacgggc caatgggaga agatggctct gttcaaggat tcttggaagt
    19621 tttgaaaatg ccttacgttg gttgcaacat tttgtcatca agtcttgcca tggataaaat
    19681 cacgactaag cgtgttctgg aatctgctgg tattgcccaa gttccttatg tggctatcgt
    19741 tgaaggcgat gatgtgactg ctaaaatagc tgaagtggaa gaaaaattgg cttatccagt
    19801 cttcactaag ccgtcaaaca tggggtctag tgtcggtatt tctaagtctg aaaaccaaga
    19861 agaactccgt caagccttaa aacttgcctt ccgatatgac agccgtgtct tggttgagca
    19921 aggagtgaat gcccgtgaaa ttgaggttgg cctcttgggt aactacgatg tcaagagcac
    19981 gctacctgga gaagttgtca aggacgttgc cttttatgac tacgatgcca agtatattga
    20041 taacaaggtt actatggata ttcctgccaa aatcagtgat gatgtggtgg ctgtcatgcg
    20101 tcaaaatgca gaaacagcct tccgtgccat tggtggcctt ggtctatctc gttgcgattt
    20161 cttctataca gataagggag agatttttct caacgagctc aataccatgc caggtttcac
    20221 ccagtggtct atgtacccac tactttggga aaatatgggg atcagctacc cagaactaat
    20281 cgagcgtttg gttgaccttg ccaaggaaag ttttgacaag cgcgaagcgc atttgatata
    20341 aaatgaaaga gagggtagaa gccagaacca tcactgcaag gtgactagag ttctcggact
    20401 tcagcccttt ttaaaggagt agaaatgaaa ttaacaatcc atgaaattgc ccaagttgtt
    20461 ggagccaaaa atgatatcag tatctttgag gacactcagt tagaaaaagc tgagtttgat
    20521 agtcgtttga ttggaactgg agatttattt gtgccactta aaggtgcgcg tgatggccat
    20581 gactttattg aaacagcctt tgaaaatggt gcagcagtaa ccttgtctga gaaagaggtc
    20641 tcaaatcatc cttacatttt agtagatgat gttttgacag cctttcaatc cctagcatcc
    20701 tactatcttg aaaaaacgac tgttgatgtc tttgctgtta caggttcaaa tggcaagaca
    20761 acgactaagg atatgttggc gcatttactg tcaacaagat acaagaccta caaaacacaa
    20821 ggcaattaca ataatgagat tggccttcct tacacagttc ttcatatgcc tgaaggaaca
    20881 gaaaagttgg ttttggagat gggacaggat cacttgggag atattcatct cttgtctgaa
    20941 ttggctcgtc caaaaacagc catcgtgacc ttggttggag aagctcattt ggcctttttc
    21001 aaagatcgtt ctgagattgc taaaggaaaa atgcaaattg cagacggaat ggcttcaggt
    21061 tccttgcttt tagcgccggc tgaccctatc gtagaggact atttgccaat tgataaaaag
    21121 gtggttcgtt ttggtcaagg agcagagctg gaaattactg acttggttga gcgtaaggac
    21181 agtctgacct ttaaggctaa tttcttggaa caagcccttg atttgccagt aactggcaag
    21241 tacaatgcga caaatgctat gattgcatcc tatgttgcct tgcaagaagg agtttcagag
    21301 gagcaaattc gtttggcatt ccaacatctt gaattgacgc gtaaccgtac cgagtggaag
    21361 aaagcagcca atggagcaga tatcctgtca gatgtttaca atgccaatcc aactgctatg
    21421 aaactgattt tagagacttt ctctgccatt ccagccaatg aaggtggcaa gaaaattgca
    21481 gtgttggcgg atatgaagga gcttggtgac cagtctgttc aacttcataa tcagatgatt
    21541 ttgagcctct ccccagatgt gcttgatatc gttattttct atggagaaga tattgctcag
    21601 ttggctcaat tggccagtca aatgtttcca atcggccacg tttactactt caagaaaaca
    21661 gaagaccagg atcaatttga agacctagtc aagcaggtta aggaaagcct tggagcctat
    21721 gaccaaatct tgctaaaagg ttctaactct atgaatctag ccaaattggt agaaagttta
    21781 gaaaatgaat gcaagtgatt ttgctaagta tcttcaaaga atgattgctc ttacagatac
    21841 tggactaacc tttacaaagg atccgtttga ccgtgagcgc tacgaagact tgcgaagtct
    21901 gttatctgaa atgttgaatc aggtatcaga cctggatgca gacgaagtgg cagaactctt
    21961 gaaaccgacc tccgcttatg cgactccttt aatggacgtc cgtgcttgga tagttgagga
    22021 tgaaaaaatt tgtctggtta ggggacaagg agagaatgat tgggctttgc caggtggctt
    22081 tggcgaggtc ggttattcac caactgaaaa tattctcaag gaaattgaag aagaaaccgg
    22141 ttttaaagcc aaagttgaac gactactagc tgtttttgat accaatcgtt tccaactaca
    22201 gagcaaacaa tatgcaaagt ttgtttttga atgtaagctt ctcgatggac aatttcaaga
    22261 aaatcaagaa atcgctgacc ttcaattttt tgcaattgac caactgccga atttatctga
    22321 aaaacgcatt accaaggagc aaatagagct tctttggcag gtttatcaag gtcatagggg
    22381 gcaatatctt gactaagaag atgattatcg tatttctaaa tccattttta acaactagca
    22441 tggtataata atatgcagga aaattttgaa ttatgaggaa gactagatga atttatggga
    22501 tattttcttt acgactcagg caaccgagcc gcccaaattt gacctttttt ggtatgttag
    22561 cctatttacg ctcttagcct taacctttta tacagcccat cgctatcgtg aaaataaggt
    22621 ttaccaacga tttttccaaa tcttgcagac tgttcagtta atccttcttt atggttggta
    22681 ctgggtcaat catatgccac tgtcagaaag cctacccttt taccattgcc gtatggctat
    22741 gtttgtggta ctcttgcttc ctggtcaatc caaatataaa caatactttg cattattggg
    22801 aacatttggg acattagcag cctttgttta tccagtgcca gatgcttacc cttttccaca
    22861 tatcaccatt ctatccttta tctttggtca tttagcactc ttggggaact ctctagttta
    22921 tctattgaga cagtataatg cgcgattgct ggatgtgaag ggaatttttc tcatgacctt
    22981 tgccctaaat gccttgattt ttgtggtcaa tttggtgaca ggtggcgatt acggattttt
    23041 gacaaaaccg ccattggttg gggatcacgg tctagtagct aattatttac ttgtttcaat
    23101 tgtgctggta gctactatca gtttgactaa gaaaatctta gaattctttt tagctcaaga
    23161 agcagaaaaa atgattgcaa aggaagctta acacagagct ttcttttttg ctcttagaga
    23221 gtttttacaa gcagcttata aaataagaat ttctgaatag acaaactcaa aaaatggctg
    23281 ggaaatttag gaaaaaagca agcacgatta aattttttgt gttataatat tttgtgaata
    23341 gctatgccta tgtttagcta tggaataata cgaagtgcga aacttggaag atagagagga
    23401 agcgatgtaa tggctagaga aggctttttt acaggtctag atattggaac aagctctgtc
    23461 aaggtgcttg tggccgagca gagaaatggt gaattaaatg taattggcgt gagtaatgcc
    23521 aaaagtaaag gtgtaaagga tggaattatt gttgatattg atgcagcagc aactgctatc
    23581 aagtcagcca tttcccaagc ggaagaaaag gcaggcattt cgattaaatc agtgaatgtc
    23641 ggcttgcctg gtaatctttt gcaggtagaa ccaactcagg ggatgattcc agtaacatct
    23701 gatactaagg aaattacgga tcaagatgtt gaaaatgttg tcaaatcagc tttgacaaag
    23761 agtatgacac ctgaccgtga agtcattacc tttattcctg aagaatttat tgtggatggt
    23821 ttccaaggga ttcgtgaccc acgtggcatg atgggggttc gccttgaaat gcgtggtttg
    23881 ctttatacag gacctcgtac tatcttgcac aatttgcgta agacggttga gcgtgcaggt
    23941 gttcaggttg aaaatgttat catttcacca ctagcaatgg ttcagtctgt tttgaacgaa
    24001 ggggaacgtg aatttggtgc tacagtgatt gatatggggg caggtcaaac gactgtcgct
    24061 acaatccgta atcaagaact ccagttcaca catattctcc aagaaggtgg agattatgta
    24121 actaaagata tctccaaggt tttgaaaacc tctcgcaaat tagcggaagg cttgaaactg
    24181 aattacgggg aagcctatcc gcctcttgca agcaaagaag ccttccaagt agaggttatt
    24241 ggagaagtag aagcagtcga agtgacggaa gcctacttgt cagaaattat ttctgcacga
    24301 atcaagcaca tccttgaaca aatcaagcaa gaattagata gaaggcgtct attggacctc
    24361 cctggtggta ttgtcttaat cggtgggaat gccattttac caggtatggt tgagcttgct
    24421 caggaagtct ttggcgtccg tgtcaagctt tatgttccaa atcaagttgg tatccgtaat
    24481 ccagcctttg cgcatgtgat tagtttatca gaatttgcgg gtcaattaac agaagttaat
    24541 cttttggctc agggagcgat aaaaggtgag aatgacttaa gtcatcagcc aattagtttt
    24601 ggtgggatgc tgcaaaaaac agctcagttt gtacaatcaa cgcctgttca accagctcct
    24661 gctccagaag tagagctggt ggcgcctaca gaaccaatgg cggatttcca acaagcttca
    24721 caaaataaac cgaaattagc agatcgtttc cgtggcttga tcggaagcat gtttgacgaa
    24781 taaagaggaa aaataaatta tgacattttc atttgataca gctgctgctc aaggggcagt
    24841 gattaaagta attggtgtcg gtggaggtgg tggcaatgcc atcaaccgta tggtcgacga
    24901 aggtgttaca ggcgtagaat ttatcgcagc aaacacagat gtacaagcat tgagtagtac
    24961 aaaagctgag actgttattc agttgggacc taaattgact cgtggtttgg gtgcaggagg
    25021 tcaacctgag gttggtcgta aagccgctga agaaagcgaa gaaacactga cggaagctat
    25081 tagtggtgcc gatatggtct tcatcactgc tggtatggga ggaggctctg gaactggagc
    25141 tgctcctgtt attgctcgta tcgccaaaga tttaggtgcg cttacagttg gtgttgtaac
    25201 acgtcccttt ggttttgaag gaagtaagcg tggacaattt gctgtagaag gaatcaatca
    25261 acttcgtgag catgtagaca ctctattgat tatctcaaac aacaatttgc ttgaaattgt
    25321 tgataagaag acaccgcttt tggaggctct tagcgaagcg gataacgttc ttcgtcaagg
    25381 tgttcaaggg attaccgatt tgattaccaa tccaggattg attaaccttg actttgccga
    25441 tgtgaaaacg gtaatggcaa acaaagggaa tgctcttatg ggtattggta tcggtagtgg
    25501 agaagaacgt gtggtagaag cggcacgtaa ggcaatctat tcaccacttc ttgaaacaac
    25561 tattgacggt gctgaggatg ttatcgtcaa cgttactggt ggtcttgact taaccttgat
    25621 tgaggcagaa gaggcttcac aaattgtgaa ccaggcagca ggtcaaggag tgaacatctg
    25681 gctcggtact tcaattgatg aaagtatgcg tgatgaaatt cgtgtaacag ttgtcgcaac
    25741 gggtgttcgt caagaccgcg tagaaaaggt tgtggctcca caagctagat ctgctactaa
    25801 ctaccgtgag acagtgaaac cagctcattc acatggcttt gatcgtcatt ttgatatggc
    25861 agaaacagct gaattgccaa aacaaaatcc acgtcgtttg gaaccaactc aggcatctgc
    25921 ttttggtgat tgggatcttc gccgtgaatc gattgttcgt acaacagatt cagtcgtttc
    25981 tccagtcgag cgctttgaag ccccaatttc acaagatgaa gatgaattgg atacacctcc
    26041 atttttcaaa aatcgttaag taaatgaatg taaaagaaaa tacagaactt gtttttcgag
    26101 aagttgcaga ggctagtctg agtgctaatc gagagcgtgg ttcggtctct gtcattgcag
    26161 ttaccaagta tgtagatgta ccgacagcgg aagccttgct tccgctaggt gttcatcata
    26221 tcggtgaaaa tcgtgtagat aagtttctgg aaaaatatga agctttaaaa gatcgagatg
    26281 tgacttggca tttgattggt accttgcaaa gacgtaaggt gaaagatgtc attcaatacg
    26341 ttgattattt ccatgcattg gactcagtaa agctagcagg ggaaattcaa aaaagaagtg
    26401 accgagtcat caagtgtttc cttcaagtaa atatttctaa agaagaaagc aaacacggtt
    26461 tttcgagaga ggaactgctg gaaatcttgc cagagttagc cagactagat aagattgaat
    26521 atgttggttt aatgacgatg gcaccttttg aggctagcag tgagcagttg aaagagattt
    26581 tcaaggcgac ccaagattta caaagagaaa ttcaagagaa acaaattcca aatatgccta
    26641 tgaccgagtt aagtatggga atgagtcgtg attataaaga agcgattcaa ttcggttcca
    26701 cttttgttcg tataggtaca tcatttttta agtaggagag aaccatgtct ttaaaagata
    26761 gattcgatag atttatagat tattttacgg aggatgagga ttcaagtctc ccttatgaaa
    26821 aaagagatga gcctgtgttt actccagtaa attcttcaca ggaaccggct ctcccaatga
    26881 atcaaccttc acagtcggct ggtacaaaag agaacaatat caccagactt catgcaagac
    26941 aacaggaatt ggcaaatcag agtcagcgtg caacggataa ggtcattata gatgttcgtt
    27001 atcctagaaa atatgaggat gcaacagaaa ttgttgattt attggcagga aacgaaagta
    27061 tcttgattga ctttcagtat atgacagagg tgcaggctcg tcgttgtttg gactatttgg
    27121 atggagcttg tcatgtttta gctggaaatt tgaaaaaggt agcttctacc atgtatttgt
    27181 tgacaccagt gaacgttatt gtaaatgttg aagatatccg tttaccagat gaagatcaac
    27241 agggtgagtt cggttttgat atgaagcgaa atagagtacg ataatgattt ttttaattcg
    27301 tatgatttat aatgcagtgg atatttactc cctgattttg gtagccttcg ctgtcatgtc
    27361 ttggtttcca ggtgcctacg aatccagttt aggtcgttgg attgtagcgt tggtgaaacc
    27421 agtgcttgct cccttgcaac gcctgccttt acagatagcg ggtcttgatt tatctgtttg
    27481 ggttgcgatt gttttggttc gatttttagg agaaaaccta gtgcgttttc tggcgatgat
    27541 aggatgaata aagggattta tcagcatttc tccatagaag atcgtccatt tcttgacaag
    27601 ggaatggaat ggataaagaa ggtagaagat agctatgctc cttttttaac tccttttatc
    27661 aatcctcatc aggagaagct attaaagatt ttggccaaaa cctatggtct tgcttgtagc
    27721 agtagtgggg aattcgtctc gagtgagtat gttcgagttt tattataccc agattatttc
    27781 caaccagagt tttcagattt tgaaatatct ctccaggaaa ttgtgtattc caataaattt
    27841 gaacatttaa cgcatgctaa gattttaggg acagtcatca atcaattagg gattgaacgg
    27901 aaactttttg gagatatcct agtagatgaa gaacgggcgc agattatgat taatcagcag
    27961 tttcttcttc tctttcaaga tggactaaag aaaattggtc gtatacctgt ttcgctggag
    28021 gaacgtcctt tcaccgagaa aatagataag ctagaacagt atcgagaact ggatttatct
    28081 gtgtctagtt ttcgattaga tgttctttta tcaaatgttt tgaaactatc taggaatcaa
    28141 gcaaaccagt tgattgaaaa gaaacttgtc caagtaaatt atcatgtggt agacaaatca
    28201 gattacactg ttcaagttgg agacttgatt agtgtgagaa aatttggtcg cttgagatta
    28261 cttcaagata agggacaaac gaaaaaagag aagaaaaaaa taaccgtcca gttattatta
    28321 agtaagtgag gaatagaatg ccaattacat cattagaaat aaaggacaag acttttggaa
    28381 ctcgattcag aggttttgat ccagaagaag tcgatgaatt tttagatatt gtggttcgtg
    28441 attacgaaga tcttgtgcgt gcgaatcatg ataaaaattt gcgtattaag agtttagaag
    28501 agcgtttgtc ttactttgat gaaataaaag attcattgag ccagtctgta ttgattgccc
    28561 aggatacagc tgagcgagtg aaacaggcgg cgcatgaacg ttcaaacaat atcattcatc
    28621 aagcagagca agatgcgcaa cgcttgttgg aagaagctaa atataaggca aacgagattc
    28681 ttcgtcaagc aactgataat gctaagaaag tcgctgttga aacagaagaa ttgaagaaca
    28741 agagccgtgt cttccaccaa cgtctcaaat ctacaattga gagtcagttg gctattgttg
    28801 aatcttcaga ttgggaagat attctccgtc caacagctac ttatcttcaa accagtgatg
    28861 aagcctttaa agaagtggtt agcgaagtac ttggagaacc gattccagct ccaattgaag
    28921 aagaaccaat tgatatgaca cgtcagttct ctcaagcaga aatggaagaa ttacaagctc
    28981 gtattgaggt agccgataaa gaattgtctg aatttgaagc tcagattaaa caggaagtgg
    29041 aaactccaac tcctgtagtg agtcctcaag ttgaagaaga gcctctgctc gtccagttgg
    29101 cccaatgtat gaagaaccag aagtagctcc agtgcatccg acaggtccaa caccagctac
    29161 agaaactgtt gattcagcac cgggatttga agcaccgcaa gaatctgtta caattttata
    29221 agaaatattc tgagaacaat atcttatcct tatattccca gcgagcagga gatggtgtga
    29281 gtcctgcatt ccctatcgat aagattatcc tctcaaacta tcaagtctga atctagtaag
    29341 atttgacgtt ccccacgtta cgggataaga gggagaaaga ctaaaacttt ttccgaataa
    29401 aggtggtacc acgattttcg tcctttttgg aagtcgtggt ttttaatttg ttattattta
    29461 taaaggagat accatgaaac taaaagatac ccttaatctt gggaaaacag ctttcccaat
    29521 gcgtgcaggc cttccgacca aagagccagt ttggcaaaag gaatgggaag atgcaaaact
    29581 ttaccaacgt cgtcaagaac taaatgaagg gaaaccgcat tttgtcttgc atgatggccc
    29641 tccatacgca aatggaaata tccacgttgg acatgccatg aatcatatct caaaagatat
    29701 catcattcgt tctaagtcca tgtcaggttt taactcacct tatatcccag gttgggatac
    29761 tcatggtctg ccaatcgagc aagttttggc aaagcaaggt gttaagcgca aagaaatgga
    29821 tttggttgag tacttgaaac tttgccgtga atacgctctt tctcaagttt ataaacaacg
    29881 tgatgatttc aagcgcttgg ggatgtcagg tgactgggaa aatttatatg tgactttaac
    29941 tccagactac gaagcagccc aaatccgtgt atttggtgag atggctaata agggttatat
    30001 ctaccgtggt gctaagccag tttactggtc ttggtcatct gagtcagccc ttgccgaagc
    30061 ggaaattgaa taccatgatt tggtttcaac ttccctttac tatgccaata aggtaaaaga
    30121 tggcaaaggt gttctagata cagatactta tatcgttgtt tggacaacta ctccatttac
    30181 tatcacagct tctcgtggtt tgactgttgg tgcagatatt gattacgttt tggttcaacc
    30241 tgctggtgaa actcgtaagt ttgtcgttgc tgcagaattg ttgactagct tgtctgagaa
    30301 atttggctgg gttgatgttc aagttttggc aacttaccgt ggtcaagaac tcaaccacat
    30361 cgtaacagaa catccatggg atacagctgt agatgaattg gttatccttg gtgaccacgt
    30421 tacaactgac tctggtacag gtattgtcca tacagcccct ggttttggtg aggacgatta
    30481 caatgttggt attgctaata atcttgaagt cgcagtgact gttgatgaac gtggtatcat
    30541 gatgaagaat gctggtcctg aatttgaagg tcaattctat gaaaaggtag ttccaactgt
    30601 tattgaaaaa cttggtaacc tccttcttgc ccaagaagaa atctctcact catatccatt
    30661 tgactggcgt accaagaaac caattatctg gcgtgcagta ccacagtggt tcgcctctgt
    30721 ttcaaaattc cgccaagaaa tcttggatgc tattgataaa gttaaattcc atacagaatg
    30781 gggtaaagta cgtctatata atatgattcg tgaccgtggt gactgggtta tctctcgtca
    30841 acgtgcttgg ggtgttccac ttccaatctt ctatgcagaa gacggtacag ctatcatgac
    30901 agctgagact attgaacatg tggcgcaact ctttgaagta catggttcaa gcatttggtg
    30961 ggaacgtgat gccaaggacc tcttgccaga aggatttaca catccaggtt ctccaaatgg
    31021 ggagttcaag aaagaaacag atattatgga tgtatggttt gactcaggtt catcatggaa
    31081 tggtgttttg gtaaatcgtc caaatctgac ttatccagct gacctttacc ttgaaggttc
    31141 tgaccaatac cgtggttggt tcaactcatc actcattaca tctgttgcca accatggcgt
    31201 agcaccttac aaacaaatct tgtcacaagg ttttgccctt gatggtaaag gtgagaagat
    31261 gtctaaatct cttggaaata ccattgctcc aagcgatgtt gaaaaacaat tcggtgctga
    31321 aatcttgcgt ctctgggtaa caagtgttga ctcaagcaat gacgtgcgta tctctatgga
    31381 tattttgagc caagtgtctg aaacttaccg taagattcgt aacactcttc gtttcttgat
    31441 tgccaataca tctgacttta acccagctca agatgtagtc gcttacgata aacttcgttc
    31501 agttgataag tacatgacta ttcgctttaa ccagcttgtc aagaccattc gtgatgccta
    31561 tgcggacttt gaattcttga cgatctacaa ggccttggtg aactttatca acgttgactt
    31621 gtcagccttc taccttgatt ttgccaaaga tgttgtttac attgaaggtg ccaaatcact
    31681 ggaacgccgt caaatgcaga ctgtcttcta tgacattctt gtcaaaatca ccaaactctt
    31741 gacaccaatc cttcctcaca ctgcggaaga aatctggtca tatcttgagt ttgaaacaga
    31801 agacttcgtc caattgtcag aattaccaga agttcaaact tttgctaacc aagaagaaat
    31861 cttggataca tgggcagcct tcatggactt tcgtggacaa gcacaaaaag ccttggaaga
    31921 agctcgtaat gcaaaagtta tcggtaaatc acttgaagca cacttgacag tttatccaaa
    31981 tgaagttgtg aaaactctac tcgaagcagt aaacagcaat gtagcacaac ttttgatcgt
    32041 gtctgagttg accatcgcag aaggaccagc tccagaagct gcccttagct tcgaagatgt
    32101 agccttcaca gttgaacgtg ctgctggtga agtatgtgac cgttgccgtc gtattgaccc
    32161 aacaacagca gaacgcagct accaggtagt tatctgtgac cactgtgcaa gcatcgtaga
    32221 agaaaacttt gtggaagcag tcgcagaagg atttgaagag aaataagatt gaaaagtcta
    32281 ggcaaaattc aatttgagaa gaaaagacaa ctaattttat agtctattaa acgcattgta
    32341 tcacgttttt gaacacctga tacgatgcgt tttttattta ttttaaaaat ttgcgaggta
    32401 tgacttttta tactcaacaa gaatcaaaga gaaacttagc aagctaacag tagtaagata
    32461 aaataggaat ttgatattag ggataagatt gctaaatagt
//
LOCUS       DBEJNA010000030        27792 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEJNA010000030 DBEJNA010000000
VERSION     DBEJNA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.30"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..120
                     /locus_tag="ACL3JB_001471"
     CDS             <1..120
                     /locus_tag="ACL3JB_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0686183.1"
                     /translation="RDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQAKER"
     gene            complement(172..759)
                     /locus_tag="ACL3JB_001472"
     CDS             complement(172..759)
                     /locus_tag="ACL3JB_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0686184.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            1001..1672
                     /gene="sdaAB"
                     /locus_tag="ACL3JB_001473"
     CDS             1001..1672
                     /gene="sdaAB"
                     /locus_tag="ACL3JB_001473"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0686185.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1681..2553
                     /gene="sdaAA"
                     /locus_tag="ACL3JB_001474"
     CDS             1681..2553
                     /gene="sdaAA"
                     /locus_tag="ACL3JB_001474"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0686186.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2575..3207
                     /locus_tag="ACL3JB_001475"
     CDS             2575..3207
                     /locus_tag="ACL3JB_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0686187.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3257..3604
                     /locus_tag="ACL3JB_001476"
     CDS             3257..3604
                     /locus_tag="ACL3JB_001476"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686188.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDE
                     VSNHIRQGDVDVI"
     gene            complement(3690..5540)
                     /locus_tag="ACL3JB_001477"
     CDS             complement(3690..5540)
                     /locus_tag="ACL3JB_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0686189.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5579..6739)
                     /locus_tag="ACL3JB_001478"
     CDS             complement(5579..6739)
                     /locus_tag="ACL3JB_001478"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0686190.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPVTFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNMLQ"
     gene            6797..7963
                     /locus_tag="ACL3JB_001479"
     CDS             6797..7963
                     /locus_tag="ACL3JB_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0686191.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            8102..8428
                     /locus_tag="ACL3JB_001480"
     CDS             8102..8428
                     /locus_tag="ACL3JB_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0686192.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            8415..9008
                     /locus_tag="ACL3JB_001481"
     CDS             8415..9008
                     /locus_tag="ACL3JB_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0686193.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            9001..9912
                     /locus_tag="ACL3JB_001482"
     CDS             9001..9912
                     /locus_tag="ACL3JB_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0686194.1"
                     /translation="MRKWTKGFLIFGVVTTIIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9975..11039
                     /locus_tag="ACL3JB_001483"
     CDS             9975..11039
                     /locus_tag="ACL3JB_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0686195.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTKIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPYQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11111..11971)
                     /locus_tag="ACL3JB_001484"
     CDS             complement(11111..11971)
                     /locus_tag="ACL3JB_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0686196.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIYLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQLEIQPILG
                     QDFKTLAQEK"
     gene            complement(12093..13079)
                     /locus_tag="ACL3JB_001485"
     CDS             complement(12093..13079)
                     /locus_tag="ACL3JB_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0686197.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMENLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13351..14826)
                     /locus_tag="ACL3JB_001486"
     CDS             complement(13351..14826)
                     /locus_tag="ACL3JB_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0686198.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14910..15833)
                     /locus_tag="ACL3JB_001487"
     CDS             complement(14910..15833)
                     /locus_tag="ACL3JB_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686199.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15847..16776)
                     /locus_tag="ACL3JB_001488"
     CDS             complement(15847..16776)
                     /locus_tag="ACL3JB_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686200.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(17095..17316)
                     /locus_tag="ACL3JB_001489"
     CDS             complement(17095..17316)
                     /locus_tag="ACL3JB_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686201.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(17270..17530)
                     /locus_tag="ACL3JB_001490"
     CDS             complement(17270..17530)
                     /locus_tag="ACL3JB_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686202.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(17956..18111)
                     /locus_tag="ACL3JB_001491"
                     /pseudo
     CDS             complement(17956..18111)
                     /locus_tag="ACL3JB_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(18873..19040)
                     /locus_tag="ACL3JB_001492"
     CDS             complement(18873..19040)
                     /locus_tag="ACL3JB_001492"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686203.1"
                     /translation="MYAANFSKEKYGFLDKKIYQNLSQSNVGKNFLEVYKEIDTKPKN
                     QISKTLVDKSI"
     gene            complement(19040..20233)
                     /locus_tag="ACL3JB_001493"
     CDS             complement(19040..20233)
                     /locus_tag="ACL3JB_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686204.1"
                     /translation="MTAEIGILNKNGVVLAADSAVTLSDGINSKVFNSARKLFTLSRV
                     HSVGIMIYGDASFMGVPWEVIISEYKKSIGNEVLADTAMYINNFVDFLLQFMPIQSND
                     ALVNYIIRQTRSYLKIIHESTQEIADHRSDQGDVITLEIFKNILWEVIEEYSNDISKS
                     ISETEFEYLDGELDLIREQLDEYFNNNEYSDEQLNFLSKTIYKAMLVGFDRNSVTGLV
                     IAGYGVEEIFPSLRQIELSGVFAKRLVWRVITEKEISQNVACHIIPFAQSEMVDTIMN
                     GIDPMLNAFIGQQINEILESNNISDAQEELFETIARVQQQYYINPIFELIGMQPIDEM
                     ASTAKTFIELTSFKRKIVNTLETVGGPVDVLAISKGEGPIWIERKHYFNIENNIDYKI
                     RKGDI"
     gene            complement(20609..21019)
                     /locus_tag="ACL3JB_001494"
     CDS             complement(20609..21019)
                     /locus_tag="ACL3JB_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HGR0686205.1"
                     /translation="MYELSNRDLDGIDIELGRYRTLASKIYLRRQELIHNKKHSTEDY
                     TGGKGKTVYSPTEATIIRIEEDQTLRYLEGFKLIVDTLMENLIDTDLVIFKMRFLEAG
                     VTWEDVAEKLNKTTRYINSRRKVIAKRFIELKGY"
     gene            complement(21397..21945)
                     /locus_tag="ACL3JB_001495"
     CDS             complement(21397..21945)
                     /locus_tag="ACL3JB_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686206.1"
                     /translation="MDINQVFDTLDDLDNKKSKIYSAREQLSEKRKSLLGIQTVSFEN
                     INSFLSNNLESLEKLEKMEKAINSLQEKYNSDFSEAKAVIFEYIFKETKQRMETKKIY
                     KQYRKKLRRILDAYDEIQELKKDVEEIHTGVVREISQKHSLSLYRTEVSPLTVLPFLN
                     PDISGWMDFSKEYRDIKEYLEK"
     gene            complement(21955..22815)
                     /locus_tag="ACL3JB_001496"
     CDS             complement(21955..22815)
                     /locus_tag="ACL3JB_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGR0686207.1"
                     /translation="MTTNLVKQKENLEAYIRSTGYNTRGMNVENNHVLIEKPILDSYE
                     DEHQRKELVDLVNVIETRTRGGKYEVTDFESDSLQEISENFVERTESDKKKTISVDYL
                     VKLFSGKLDFSQEQLDDGQYNLTDFLGKKIIKLKRRTRNREIGKILQTAKVQTATSLD
                     DLKSIVSLINPERNVSIVISQSLFSVLEKMKDTSGNYLLKVDKETGTSETFFVDNFLI
                     VDDTTLGNEGDKKGFIGDLENFVTLFDRKKDTLSWVNANDYFRKRLILHTRFDVKKVE
                     EDCGYFIQWN"
     gene            complement(22865..23047)
                     /locus_tag="ACL3JB_001497"
     CDS             complement(22865..23047)
                     /locus_tag="ACL3JB_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686208.1"
                     /translation="MDPDKRQKIFSQCKKEGDSLEQRKQEILEKYANKQDKPKSRKND
                     SKGSESHKRKTKSKEF"
     gene            23050..23154
                     /locus_tag="ACL3JB_001498"
                     /pseudo
     CDS             23050..23154
                     /locus_tag="ACL3JB_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505376.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            23316..24482
                     /locus_tag="ACL3JB_001499"
     CDS             23316..24482
                     /locus_tag="ACL3JB_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0686209.1"
                     /translation="MQIKQITKKDGSIVYRANVYLGVDKVTGKDVKTSITGRTKKEVK
                     QKTKEAEIAFLQNGSTRFQASNITTYKELASLWWESYKHTVKPNTQLNVRRLLDNHIL
                     PLFGSYKLDKLTTPLIQNIVNKLADKTNKGEEGAFLYYDSLHALNKRILQYGVVMQAI
                     PFNSAREVILPRNTQKAKREKVKHFDNDELKSFLKYLDTLDLSRYRYYYEITLYKFLL
                     ATGCRINEALALSWSDIDLDNAIVHITKTLNYNQELNSPKSKSSYRDIDIDQATVSML
                     KQYKHRQVQEAWQLGRSETVVFSDFINEYPNNRTLQTRLRTHFKRADVPNIDFHDFRH
                     THASLLLNSGIPYKELQHRLGHSQLSMTMDIYSHLSKENAKKAVSFYETALKSL"
     gene            complement(24576..25187)
                     /gene="rpsD"
                     /locus_tag="ACL3JB_001500"
     CDS             complement(24576..25187)
                     /gene="rpsD"
                     /locus_tag="ACL3JB_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0686210.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(25382..26434)
                     /locus_tag="ACL3JB_001501"
     CDS             complement(25382..26434)
                     /locus_tag="ACL3JB_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0686211.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(26431..27129)
                     /locus_tag="ACL3JB_001502"
     CDS             complement(26431..27129)
                     /locus_tag="ACL3JB_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0686212.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(27296..>27792)
                     /locus_tag="ACL3JB_001503"
     CDS             complement(27296..>27792)
                     /locus_tag="ACL3JB_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HGR0686213.1"
                     /translation="ALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDN
                     IVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTN
                     TMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNK
                     KEEN"
BASE COUNT         8298 a         5809 c         4886 g         8799 t
ORIGIN      
        1 agggatgatg cgaaacttat ccaaaaaggt ttctcactcc tagagctaac cgaggaaact
       61 tctatgctgt ctcatctcaa aaaagaagta gagatctatt accaagcgaa ggaaagataa
      121 aaaagccgag ggatttcctc gactctttac atattatttg ttcgttagtt cttaatacca
      181 gccattgtta agccagaagt ttttagcagc tgtccatgaa ccgtaacgtc ctgcaacgta
      241 ggcatctgct acacgttctt ggttttcagc tgagtagtca ccgttcaggt atgaatctgt
      301 taattggtaa cgtccgatat aacgtccatt tgtagctgta tagctaccac ctgattcttt
      361 ttgagcgatc cattctttgg cttctgcttc agatccgctt acagttgaaa caactgtttc
      421 acttactact ggagtttctg ccactggagc tgaaacagtt tcatcttgag cggctggtgc
      481 cgcataagta gctggcgctg gtgttgcaac aggcgctaca gggccatcga taaccaactc
      541 ttgatcaaca taaatcaaat gaatgttatc aatgtggttg ttttctgcca atttttcaac
      601 tgttgtgttg tgagtttcag cgatttctga aagtgtatca ccttctttaa cagtgtaagt
      661 tgatgattct tgagcagata caaatgatgg agcaaatact gcaaacaagg cagctactcc
      721 tgcaagagtt gctttaatct ttttagttat tgatttcata ttcgaaaatt ctccttcttt
      781 ctatagttct atcataccct ttaaatatta ccgtttcttg acacttttat gtagaaatat
      841 tacaaaatta ttttttattt ccctaaataa ggtgtttttt gtcataaaag atactatttt
      901 tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc ccctcattct
      961 ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac ttcgttttca
     1021 atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc ataccgctgg
     1081 tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga cagaagttga
     1141 attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag acctagccct
     1201 tgttgcaggt attttaggaa tggatacaga tgatcctgaa attccaaata gtctggaaat
     1261 tgcccacaag cgtggtatca agattgtctg gaccattcag aaagacagca atgcccctca
     1321 ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg tgactggtat
     1381 ttctatcggt ggaggaaata ttcaggtaac cgaactcaat ggttttgccg tctctctcaa
     1441 tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga ttgcccttgt
     1501 tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca ctcgtgaaaa
     1561 agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg atgaggctat
     1621 cgaagaaatt cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat aggaggaagc
     1681 atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca aggaaatgtc
     1741 gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga agaagtcttc
     1801 cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg cctcaatgaa
     1861 aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggatca ctacatcgaa
     1921 aacggaaaaa ctctgtcaga ttatacgatt ctctcggctg cccgaaatgc catcgcagtc
     1981 aatgaacaca atgccaaaat gggcttggtc tgtgccactc caaccgctgg aagtgctggc
     2041 tgtctgccat ccgttctcac tgctgctatt gaaaaattag acctcagcca cgagcaacaa
     2101 ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa tgcctccatc
     2161 tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat gagtgctgcc
     2221 gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat tgcctttgtc
     2281 attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga agttccctgt
     2341 gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat ggccttggca
     2401 ggtatcgaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca agtaggagca
     2461 agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac ccctactggt
     2521 cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga aaccatgacc
     2581 tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc tatcgggatt
     2641 cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga tgccaaaact
     2701 attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct gtccaaagac
     2761 caaatttctg aagccatgca gatatatcgt tcttactata aggcaaaagg catctatgaa
     2821 gctcaactct ttcctcagat tatagacttg cttgaggagt tatcgagcag ttatccactc
     2881 tacatcacca cgacaaagaa tacatctact gctcaagaca tggcaaaaaa cttggaaatc
     2941 catcatttct ttgatggtat ttatggttct agccctgaag caccccataa ggcagatgtc
     3001 attcaccaag ccttgcagac acatcaacta gcaccagaac aagccatcat catcggagat
     3061 accaagtttg atatgctggg agctcgagaa acaggtattc agaaattggc cgtcacttgg
     3121 ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc tcacaaaccc
     3181 ttagaagttt tggcgtattt tcaatagcat agactgggta acaactccat ttcagaagaa
     3241 aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg cgggctgctc
     3301 aaaacactgt tttaagattg tagatggaac tgacgaagtc agctcaaaac actgttttaa
     3361 ggttgtggat ggaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac
     3421 tgacgaagtc agctcaaaac actgttttaa ggttgtagat ggaactgacg aagtcagctc
     3481 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
     3541 ggttgtggat agaactgacg aagtcagtaa ccatatacgg caaggcgacg ttgacgtgat
     3601 ttgaagagat tttcgaagag tataagtctc tacataataa aacgcatatt accaaggttg
     3661 tttaacttga taatatgcgt ttttcttttt tattcaatgt gggttgtttg attagcaaag
     3721 gcgataatag cttgcttcaa ctcatctcca ctgagagtgc ggaactctcc aatcttttga
     3781 ttgatggatt ctaaaggcat gacattaacc ttaccaacga aaatcttatc cataacttga
     3841 ttgtcaacga gttcggttga taccaagagt tcttcgtaga gtttttcacc tgggcggatt
     3901 ccaacttcaa cgattggaat ttcactttca gtgtggccac ttagaagcac catcttcttg
     3961 gccaagtcat aaatcttgac tggtttgccc atatcaagga taaagacttc cccatctttg
     4021 gcataagcac cagcatggat aaccagacgg ctagcttctg gaatggtcat aaagtaacgg
     4081 gtcatgcgga agtctgtcac cgttacaggc ccaccttcag caatctgacg ttcaaagact
     4141 ggaatgacac taccacggct accaagaaca ttcccaaaac gaactgcaca gtaggttgat
     4201 tggctacgtt ggttaaagcc agtgacaatc aactccgcca cgcgcttggt tgctcccata
     4261 acatttggtg gattgactgc cttatctgtc gaaatcataa ccatcttaga cactttagct
     4321 tcatcaacag ccttagcaac attgtaagtt ccacggatat tgtttttgaa ggcttctttt
     4381 ggattgcgct ccatcatagg aacatgcttg tgggctgccg catgataaac aatagcaggt
     4441 ttgtactgtt caaagacttg caacaaacga tcatagtctt gaatgtccgc aatcacaggt
     4501 acataatcaa tcccttggaa cttacgaatc aattcatgat aaacaaggta gattgagttt
     4561 tccccatgac cgagcaagac aatgcgttca ggattgaagc gactaacttg acgacagatt
     4621 tcagaaccga ttgaacctcc agctcctgtg actaagatgg tcttacctgt cagttctgca
     4681 cccagacgcg attcgtcaag acggatttcc tgacgaccca aaaggtccgt aatatcaatt
     4741 ttttggaagc cagtacctgc ttggtgaagg ccctgaacaa cagtttcaac cttaggcatc
     4801 ttgtaacatt tgacacccag cttattacac atctgcaaga tacgctcata ttctgacgga
     4861 tccagcgacg gaatcgcaac gatgacacgc tcgatttgat ggcgtttggc taattcaggc
     4921 agattgtcat aagagcccaa aacaggaata ccaccaagtt tttgaccctt tttcttagaa
     4981 tccttatcca aaataccgac cagttctaat tcactggttg gatgttggta actatccata
     5041 aagagagccc caccatcacc ggcaccaatc aagaaggtcc gacggtgttc tccatcacca
     5101 ctaccttttt tgcgtctgga gtagattaac tgccaagtaa tccgtggcaa taaaatcaag
     5161 aaggtactca acaagataaa gagaatgata aaacggatgg agaagagtgg caagaaggca
     5221 taacagatac tatatgacaa gacactgcta gcagtcacac caaaaaagat tttcatgaaa
     5281 tccgtaatct tgctgtaacg actaatgctc gcgttcaacc cccaaaaacc aatcatcaat
     5341 tgatagaaca ggaaggccaa actcgtatag ataatgtagt caacaggtgc tggattaatc
     5401 agcccataaa ataaaatata agatacaatt atggaaacca ccatactgaa aatatcaaat
     5461 attccccaga aaacctgctt ttgttgttta tttaaaattt ccaccagatc aatcacataa
     5521 tctgttagtt ttttattcat agaaatctac tcctccttaa aagagtttta ctatattgtt
     5581 attgtagcat attttgattt atttggctta ttttatccaa ataaattatt gttctcttgt
     5641 actccttctt ccatttaaat cctctaatta aacctacaat cgtcccaagg ccataagcaa
     5701 agtgaatgga aaataaaaga aagggcatca caattagaaa tccattttta tgttttaata
     5761 aagtcagcaa agtgagtaat gacaaaagta gaaaataggc acctaatagt aaagttatga
     5821 atacgaatgt gaccggtaac aatgctagac taaacacaag actcaaaaca aataaacaag
     5881 gaacatagtg aaataatgat aaacacttaa actgaacatg acttgtcaag ccaatccaca
     5941 aaccatttga atacttttga tgcagcattt tcttgaatgt tggtcgaata tactgataag
     6001 atagaatact tgggctatag cggattttat aaccatgttc tcgaattcta taatgaatat
     6061 cattatcttc agttcggcca agttgctcat ttactaaacc aaccttctgg aaaacctctc
     6121 gtttatacat cccatgaaaa atagaagaaa catatctatc ctcggaacta tttcgataat
     6181 tggcaatgct actgccaaac atattttcct caacaagatg caaggtctct gcccattttc
     6241 cttttccttc gacaatcgtc ggtctaggcc ccccacagac aaattcacct tgttgaataa
     6301 tagccacatt gttcattaca aaactctcag taacttttga atgagcatca atttttaaaa
     6361 taaggtcccc tacagaatgt ttaactccca ggttaaaacc actagcttga tttttcttag
     6421 gattgttata caatctaatt gagttaaact ctgtatcttc ctttataaat tgctgaatga
     6481 tagctgtggt cccatctgtg gacatagcat ttataaatag aatttcaata ttctctttag
     6541 gataggtttg attttttaag tcttcaatta gaccaggcag atatttttct tcattgtatg
     6601 cactgattac aatggatacg agaagacttt caacattttg agtcactact actctcctga
     6661 atttttcctt ccaccattct atcataattt tcaagacttt cccattttta tcttgaaagc
     6721 cagaaacctt acttgacatt atagtgaaaa agccttaaaa taagctgtta ttaaaatcag
     6781 ctataagagg tattatatga aaaagcaatc actctttttt gttccaggta ttatcctgat
     6841 tggtgtttcc ttgcgaactc cttttactgt tttacccatt attttgggaa atatttcgca
     6901 aggtctagag gtagaagtta gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt
     6961 taccctcttt tcaccatttt ctacccaact ggctcagaaa atcggcttgg agcatctctt
     7021 cacctacagc ctcttcttct tgaccatcgg ctcacttatt cgactaatca atctgcccct
     7081 actctatcta ggaaccttga tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc
     7141 tagtcttatc caagccaatc aaccaaagaa aattggtttt ctgaccacct tatatgtaac
     7201 gtctatgggg attgcaacgg ctctggcttc ctatctagct gtgcccatta cacaagccag
     7261 ttcttggaaa ggacttatcc ttctcctcac gttactctgt ctagcaactt ttttggtctg
     7321 gctcccaaat caccgctata atcatagact agctccacaa accaaacaaa aaagtcaaat
     7381 aaaggtcatg cgtaataaac aggtttgggc aattattatc ttttcaggtt ttcaatcctt
     7441 gatcttttac accgtcatga cctggttacc taccatgtct atccatgcag gtctatccag
     7501 tcacgaagct ggcttgctga cttctatctt atctctgatt agcattcctt tttcaatgac
     7561 catcccaagc ctgacaacca gtttatctac tcgcaaccgt cagctcatgc tcactctggt
     7621 ttcactagct ggtgtggtcg gcatttccat gctctttttc ccaatcaata atttcattta
     7681 ctggcttacc atccatctcc tcatcggaac cgcaaccagc gccctcttcc cttatctcat
     7741 ggtcaacttt tcactcaaga caagcgcccc tgaaaagaca gcccaattgt ccggcctatc
     7801 tcaaacagga ggctatatcc tagcagcctt tggaccaacc ctctttggtt acagttttga
     7861 cctgttccac tcttgggtac cagctgtagc tgccctcttg ctcatctata tcctgatgac
     7921 tgtggccctc tttacagtgg acagagcgga taagatcctt taaacttcta gttttagcta
     7981 gaagtttttt atatataaaa attttacaca tttctcttga cagggctttc ttttagatgt
     8041 acaatgtatg tgtagaaaaa ttatatataa aaatcttaca cattagaaaa ggaggtttcc
     8101 catgtacttt ccaacatcct ctgccttgat tgaatttctc atcttggctg tactggagca
     8161 gggtgattct tatggttatg agattagcca aaccattaag ctgatcgcta atatcaaaga
     8221 atccacactc tatcccattc tcaaaaaatt ggaaggcaat agctttctga caacctattc
     8281 tagagagttc caaggtcgca tgcgcaaata ctactccttg acaaacggtg gtatagagca
     8341 gctcttgacc ctaaaagatg aatggacact ctatacagac accatcaatg gcatcataga
     8401 agggagtatc cgccatgaca agaactgaat acctgactca gctagaactc tatctcaaga
     8461 aactacctga agctgaccgt atcgaagcca tggactattt cagagagctc tttgacgatg
     8521 ctggagtcga aggagaagaa gaactcatcg ctagtttggg aactcccaaa gaagcggccc
     8581 acgaagttct atccaatctt ctcgataaaa aaatcaatga agcacccgct caaaaaaata
     8641 accgacaaat tttacatatc gccttgttag ccctccttgc agcacctatc ggcattcctc
     8701 tgggaatcgc catcctcgtg accctgttcg caatccttgt agccgctttg actgtcattc
     8761 tggctttctt tgcagtttcc atactgggta tcatcggcgg attcctattt ttagttgaaa
     8821 gtttcactat cctcgcccaa gccaaatcag cctttatctt gatttttggt tctggtttac
     8881 tggctatcgg tgcttcttcg ctagttttac ttggcatttc ctatgtagct cgcttcttcg
     8941 gtctactcat tgttcgtctg gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc
     9001 atgcgtaaat ggacaaaagg atttctcatc tttggtgtgg tgactaccat tatcggcttt
     9061 atcctgcttt ttgtaggtat ccaatctgac gggattaaga gcctactttc catgtccaaa
     9121 gaacctgtct atgatagccg tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta
     9181 gaaattactc tccaccaaca cgcgctcacc atcacagact ctttcgatga tcaaatccac
     9241 atttcttacc atccatctct ttctgctcac catgatctta tcaccaatca gaacgataga
     9301 actctgagtc tcactgataa gaaactgtct gaaactccgt ttctctcttc tggaattggt
     9361 gggattcttc atatcgcaag tagctactct agtcgttttg aagaagttat tctccagcta
     9421 ccaaaaggga gaactctaaa agggatcaac atctcagcca atcgcggaca aaccaccatc
     9481 ataaatgcta gccttgaaaa tgcgaccctc aatacaaaca gctatatcct ccgaattgaa
     9541 ggaagtcgta tcaaaaacag taaactcaca acgcccaata tcgttaatat ctttgataca
     9601 gttcttacag atagtcagct agagtcaaca gagaatcact tccacgctga aaatatccaa
     9661 gtccatggca aggttgaact gactgccaaa gattatctca gaatcatcct agaccagaaa
     9721 gaaagccaac gaattaactg ggacatctca agcaactatg gttctatctt ccaattcaca
     9781 agagaaaagc ctgaatcaag aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc
     9841 gatgtcaagg atcaactcat tgcgagatct gatgataata ttgatctaat atccacacca
     9901 agcagacgtt gacaaaaacg cttacatctg ctactatgaa agcatattta tctaactaaa
     9961 aaggaggttc taccatgaaa caagaatggt ttgaaagtaa tgattttgta aaaacaacaa
    10021 gcaagaacaa gcctgaagag caagctcaag aggttgcaga caaggctgaa gaaacgatag
    10081 ccgatctcga tacaccaatt gaaaaaaata ctcagttaga ggaggaagtc tctcaagctg
    10141 aagtcgaatt ggaaagccag caagaagaga aaattgaagc tcctgaagac agtgaagcga
    10201 gaacaaaaat agaagaaaag aaggcatcta attctactga agaagagcca gacctttcta
    10261 aagaaacaga aaaagtcact atagctgaag agagccaaga agctcttcct cagcaaaaag
    10321 caactacgaa agagccactt cttatcagta aatctttaga aagtccttat atcccctacc
    10381 aagctccaaa atctagggat aaatggaaag agcaagtgct tgatttttgg tcttggctag
    10441 tggaagcgat caaatctcct acaagtaagt tggaaacaag tatcacacac agttacacag
    10501 cctttctctt gctcattctg ttttctgcat cttccttttt ctttagtatc tatcacatca
    10561 aacatgctta ctatggacat atagcaagca ttaacagtcg cttccctgag cagctagctc
    10621 ctttaactct tttttctatc atctctatcc tagtagcgac aacactcttc ttcttttcat
    10681 tcctcttggg tagtttcgtt gtgagacgat ttatccacca ggaaaaggac tggacgctag
    10741 acaaggttct ccaacaatat agtcaactct tggcaattcc aatcttcctc actgctattg
    10801 ctagtttctt tgctttcttt gatagcctac gatttacagc tctcttgtgt gtaattagca
    10861 ttggaatcat tctgcttgcc agtctccata tcattacaag accaagtcaa gcaagtgaaa
    10921 ccgactcctt ctatcaatta ttcttgtctg tccttgtgaa cggagttatt atcctcctct
    10981 tctttgtagc tgaagtggca ctgattggag attatcttcg tatcttggcc tttctttaaa
    11041 attcaatcct gtcatccttg gcaggatttt ttctatgtca aaaaagcaag tcgattgacc
    11101 tgcttctgct ttacttttct tgtgctaatg ttttaaaatc ttgtcctagg atgggttgta
    11161 tttctaattg attggcgtct agctggtggt aaaaagatgg gggtaacacc tctaagaatt
    11221 ttgcatagtc caagcgagct atggattcat agtcttctgg tttagagccg tctcctgtga
    11281 tttgaaccaa gtaaatctcc cactggactt ccttatccac caattgctca atataggctg
    11341 caggaacaaa cggttctctc ggtaaaactg tcttgactcc ttgagctaaa tggtaaacgc
    11401 catgcacttt tccttctcca tcctgataga aggaaactct tgcaaagtag gcatctgtct
    11461 cttgaaccgc acgcacacgc gcttcaaact gagccaagcc atctgcctct aaaaagcttt
    11521 tcaagttctc acgactaaag aaaataggat taaaaattcc ttggcaaatc gtaaaacgag
    11581 ctacagggtc tgctagatag gcttgaatac ttgcttggaa ataagcttca aaatcaaaac
    11641 catctagccc ttcaatatca gtccctgtat aagcaagcaa agcatctaaa aatgacttga
    11701 taatctgcca gtctgtcttt gttagtaggt caggaagatc gacacggtaa gccttttgac
    11761 catcagcata actgacctta aagagaaatt gtgattgccc cactatcgca cactcaatat
    11821 actcgagacg attaagaggc tgacgaagat agactacatc atagctatgt gactccaaac
    11881 cgtctagcaa ggccaagatc gacttggcat tcaaaatctc ttgttctcct aaaatgctct
    11941 gtttatttgg aataaaaaat gtttttgcca taactggact cctttgaaat cgtttacata
    12001 cagtatacct tattttcctg aaagatacaa aaacaaactt tagatttttg agtacaaagc
    12061 atagaaaaac agcccctgag gactgtttga tcttatacag tagctgcctg atccaagctt
    12121 tcaccgatag cggctaggcg ctcaatcact tcagcttgtg tcaattcatt ttttgaaaca
    12181 tagcggttac gtgggtgaac acgacactcg tgtgagcatc cacgaaggta cttgtcttca
    12241 ttttcttctg atgtcaagat acgacggtta cagaagggat ttccacagtt gacataacgt
    12301 tcacatggtg ttccatcaaa ccagtctttc cctacgatgg ttgggttgac atggttgaca
    12361 tcaacggcaa tacgctcgtc aaagacgtac attttcccat cccaaagctc accttgaact
    12421 tctgggtctt taccgtaagt tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct
    12481 tcacggacca tccagcctga gaatttctca cagcgaacgc cacctgtaca gtaaaccacg
    12541 acacgcttgt ccatgaattt ttccttgtta tcacggaccc attgtggtaa ctcacggaag
    12601 ttgcgaatat ctgggcgaat agccccacgg aaatgtccta ggtcgtactc ataatcgtta
    12661 cgtgtgtcaa ggacaacggt atctttatca agaagcgctt ctttgaactc ttttggagac
    12721 aagtaagcac ctgttgtttc aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa
    12781 ccaaggtgga caatttcttt cttgtagcga acaaacatct tcttgaaggc ttgttcactt
    12841 tcttcgtcaa tcttgaacca gagattttcc attcctggaa ggctgtgaac gtagtccatg
    12901 tatttttgag ttgtttcata gtcacctgaa actgttccgt taattccctc gtcagcgact
    12961 aggatacggc ctttaaggcc gattgattta cagaaagcca agtggtctgc agcaaattgc
    13021 tctgcatttt caattggagt atagaggtag taaagtaaga cacgaatatc ttttgccata
    13081 agatttgttc tcttttctat tcttaaattt tctaaatttt ttatttatcc atactagtat
    13141 acctgcttga gaaaacgaat gcaatttatt tgactggaaa ttgtagaggg ttctcgaaat
    13201 ttcctgaatg gttaaaataa ggacaagaga aaacatggat atctatatcc ttgtgccaaa
    13261 aaaaccactg ccctccccag accaacctga ggaaagcggt gattcttatt ttaggagtta
    13321 ggaatgaata cacgaaatca atttagctga ttattttttg tttttcaaga attcatcgta
    13381 ttgtttttgc atttcgttca atactttttc gtaggcacct tcagatttca atttttccat
    13441 caattctgga atagctttat ctgggtctac agtaccagtg ttgatagctg tatcaaattg
    13501 ttgcattgtg ttagcaatag ctgagatttc agatttcaca ttgtcagtat tgaagataaa
    13561 tccaagcgct ggagattctt tagcttctgc caattctttc ttagaatttt cgatttgttg
    13621 gtctgtaacg ttttcgttga tgtaaaggat ccagttgtta ccagtgttcc atccacccat
    13681 gtgagtgttt cctttgtagc catcaagaac gcgaacacga ttttctttac cttcaatttt
    13741 ttcccagttc ttgccttctg gaccgtaaac aagaccgttc aagagttctg ggttcgtatt
    13801 caagaggttc aacacttcca ttgatttttc tttgttctta gagttgtttg agatgacaaa
    13861 gttagcaact tgtgttgttt ggtttttctt gatgaagtta gtaattggtt tgatttggat
    13921 atctttgttg gcaacacgtg aaagcaagct gttaccgtag tcagctggtc ctactgtttc
    13981 ttcacgaacg aaccaagtat cttgttgaag gtcaaatgaa gtatcgcttg ttgcgacatc
    14041 ttttggaatg tagccagctt catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg
    14101 aggcacttcg taacggttta caactttagt agtatcgcct tcaagatcaa taacgaatgg
    14161 aagcccgttt gctactgggt agtcaaagtt atcagatggg atgaaaactt taccaatagc
    14221 aaatggtact acgtctggag ctttttcttt aatttgtttc aagactggct caagagtttc
    14281 gtaagaagta acacctgaaa tatcgatacc atatttggca aggagagttc cgttgaaggc
    14341 aaagttttga gatgatgcaa cgttggctgc aactggaaca gcgtaaattt taccgtttac
    14401 agtattaccc ttgatgtaag ctgggtcaag tgccttgtaa aggtctttac cttctttttt
    14461 gtacaattct gtcaagtcag cataagcacc tttttgagca tttacaatat agttatctgc
    14521 aaaggcgata tcatagtttt caccagatga tgtgataact gacattttct taccatagtc
    14581 accccagcca aggtattgga tatccaattt ggcaccaact ttttcttcga tgattttgtt
    14641 ggcatttgct aacaattcat ccaagttatc tggtttgtca ccgatttggt acattttgat
    14701 aacaggtttg tcacctgaat cagcagcttt tttgctgtta cctgtcaaat ttccacaagc
    14761 agcaagacct gcagccaaag cgactacact agcagatgca aaagcatatt ttttccagtt
    14821 tttcatgata aaaactcctt tttttatttt taaacttata aacaatgtaa tgatcttaac
    14881 ttcacgcaag ggaagtttgg aaacaagtgc tattctttca caccaccgat agtcaaacct
    14941 tttacaaagt agcgttggaa aaatggatac aaaatcgcga ttggaagggt tgcaaccaca
    15001 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    15061 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    15121 tacaagttgt cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    15181 gctgttaaga gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    15241 aaaatccggg cttcactggc accatcgata cgagccgatt ctagaatggc ttctggaatg
    15301 gtcttcttga agaaggaacg catcaagatg atgttaaatg gtgagagaag cattggaaca
    15361 atcaaggccc aaacagtatc cccaagctga agtacacggg tcaccatgat ataacctggt
    15421 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    15481 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    15541 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    15601 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    15661 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    15721 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    15781 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    15841 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    15901 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    15961 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    16021 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    16081 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    16141 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    16201 tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc aaatacctag
    16261 gaaaagtagg agatagggcc agatgcccag gtcagcgtaa aaattgactt ctttgagacc
    16321 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    16381 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt ggaaaatctt
    16441 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    16501 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    16561 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    16621 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    16681 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    16741 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    16801 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    16861 tttgtaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    16921 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    16981 tagcccagtg atggcgtcac tctgttataa acatccaaca acgggggata ctgaaaaatc
    17041 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    17101 gtttgctttc aacttagcaa taacctcttt aagattatca atcacctctg cttcagtatg
    17161 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt tttgagagtt
    17221 ttcaaggaca tccttatcta ctgtttcaag gtttgagtct ttaagaagtt tacttaattc
    17281 cttggctaat ttcttgagtt tgatttgcag actcatcttc tcctgctgtt tctttgcccg
    17341 ctgtttgtcc tccatcctta gttgctgact ggctttcctt aatggactct agggaagcaa
    17401 tggcatcttt gactgtttgc aagatatcac gtaaaccttg ctctgtcaaa ctatcatctg
    17461 caaaagcttt cttagcctct gccaaaacca gacgtgctga atctgtggta ggattcgata
    17521 cacctgtcaa tgatctcaaa agattttcta aggtttgagt ctgcttacta atactagact
    17581 aaaatcaaaa agtattatat aacagtgata tgaaatcaac taaagaagaa atccaaacca
    17641 tcaaaacact tttaaaagac tctcgtacag ctaaatatca taaacgcctt caaatcgttc
    17701 tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga cagtcaaatc gatttctaac
    17761 aatgttttag aagcagaggt gtactattct agtttcaatc cattatattt cgtctgatgg
    17821 gcaaatctta taaagagatt atagagcttt tatagtagtt tgaaataaga tgtgaacaac
    17881 tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt gtactgttat
    17941 agattcaata cactatactt ggtggtttag ctctcctgtt ttctctttta gctttaacca
    18001 gccataaatg gtattacgtg agatttggaa aacgtgtgat gcttctgtta tactacctgt
    18061 tcgctcacaa taagagagaa cttttttacg aaaatctatt gaatatgcca taaaaggatt
    18121 ataccacatt gtgtactatt tttggttcat tttactatat cactttggac tatatcggtc
    18181 tagttatgtc tcaacgatta tagctggata ctaagagaaa tcaaaaaagc actctaggat
    18241 agaggcctaa agtgcttagt ttcaaggctt tacagcctat catatttaat aaaatattac
    18301 aacattttgt tgtatcgctt ttttaagtat tcagcaagta gctttattac ttcttaatgc
    18361 ttgataatag ggtgatgggg agttttcact tttcgtttga acgttttgga gtttctccct
    18421 tactccacaa atcactgaac atgataaacg agttcagcag gcaagaaact agcactattt
    18481 aaaagtgctt ttttgtttct atttaatagg aagctattgc acatctttta atatttgttt
    18541 tattagtttg catgaagcat tctaaatact cttcatcttc taatctaaaa tctaacaata
    18601 gcataaattt aatttcgtat ctgttctgtt atattggaac tctatatgta cctgttcttt
    18661 aatcttcaaa gtttagctta gattcttttt tgattgtaag tttagtattt taaaactgtg
    18721 tttttccttc ttctttaata attaatcaaa tatagtaaaa acttatccta gcgctaacat
    18781 aaagttgtta ttataaatct ctttttattt taaaatcata gtaacaatca tatttaagca
    18841 aaaacactta gaacaatcta agtgttttca ttttagatag acttgtcaac aagagtttta
    18901 ctgatttgat tttttggttt agtgtctatc tctttatata cttctaaaaa atttttccca
    18961 acattacttt gtgaaagatt ctgatatatt tttttatcta gaaatccata tttttctttt
    19021 gaaaaatttg ctgcatacat tatatatcac cctttctaat tttataatca atattatttt
    19081 caatattaaa gtagtgtttt ctttcaatcc agataggacc ttccccttta gaaatagcta
    19141 aaacatccac tggtcctcca actgtttcaa gtgtattcac aatctttctc ttaaaagaag
    19201 tcaactcaat gaatgttttt gcagtagaag ccatctcatc aataggttgc atcccaatca
    19261 actcaaaaat tggatttata taatattgtt gttggactct agcgatagtt tcaaacaact
    19321 cttcctgtgc atccgatata ttattacttt ccaaaatttc attaatttgt tgtcctataa
    19381 atgcgtttaa cattggatct atgccattca ttatagtatc taccatttcg gattgagcaa
    19441 agggaataat atgacaagca acattttggc taatttcttt ctcggtaatt acacgccaga
    19501 caaggcgttt agcaaataca ccacttaact ctatttgtct aagggatgga aaaatttctt
    19561 caacaccata cccagcaatt accaaccctg ttacagaatt tctatcaaaa ccaactaaca
    19621 ttgctttgta tattgtttta gataaaaagt ttagttgctc atcggagtat tcattattgt
    19681 taaagtactc atctagttgt tcccgtatta aatcaagttc gccatctaaa tattcaaatt
    19741 cagtttcaga tattgatttg gagatatcat ttgaatattc ttctataact tcccataaaa
    19801 tatttttaaa aatttctaga gttattacat ctccctgatc tgatctatga tcagctattt
    19861 cttgggtgct ctcgtgtatt atttttaaat aacttctagt ctgtctaatt atataattaa
    19921 ccaaggcatc attactttgt attggcataa attgcaataa aaaatcaaca aaattattaa
    19981 tgtacattgc tgtgtcagct agtacttcgt tgccaattga ctttttatac tcacttatga
    20041 ttacttccca cggtacaccc ataaaggagg catctccata aatcataatt ccaaccgaat
    20101 gcactctaga taaagtaaat aatttccgag cactattaaa cactttggag ttaatcccgt
    20161 cagataaagt caccgcgcta tctgcagcta aaacaactcc attcttattt agtattccaa
    20221 tttctgcagt caaaattgag cctccaatta ttttacataa cttaacagtt aaaaatcatt
    20281 aaatattttt caatttatac aacaattccc tttaactaat tataatacaa ttcatactaa
    20341 aagtacattc ttttaactat gcaaacacat ctccaatttc taacaatata tcatagcttc
    20401 actttaatct agaaaaatta tcttcagttt aacctcctca tttatttcaa tgacttttga
    20461 atgcatatgt ttaatttcaa aaaactagcc ttcaccttat aaatcaacaa gtttttaccc
    20521 cctttttgtc tggaggtctc cgacttagaa aaagttccct tcaccggttc tcaaagtatt
    20581 caaaaaattt ttttcaacgt ggggggagtc aatatccttt cagttctata aatcttttag
    20641 cgattacttt tcttcgacta tttatataac gagtagtttt atttagtttc tctgccacat
    20701 cttcccaagt cacaccagct tctaaaaatc tcattttaaa gatgactaga tcagtatcaa
    20761 tcagattttc catcaaggta tctacaatta gtttgaaacc ttctaaatat cttagtgttt
    20821 ggtcttcttc aattctaata atagttgctt cggtaggact atatactgtc ttgccttttc
    20881 caccagtata atcttcagtg ctatgtttct tattatgtat cagttcctgt cttcttaaat
    20941 aaattttact agcaagcgtt ctatatcgtc ctaactcaat atctatcccg tccaggtctc
    21001 tgttactcaa ctcgtacata ggcaagtacc tccacttaaa tttaaaaatt tttttatctt
    21061 tcaatttgtc aaattgtaaa ttctgtcaaa ctgacaaaaa gcgctaaaag ccttccaaca
    21121 ctccacttac caggtatcat tgttttaagt ttgacaactc ttcaatatga caagttcaag
    21181 ggaaatttct ttaatttatc ccctaagttt ctcatatctt acattctgtg aaactcactc
    21241 cattctgtaa cttactgata tatatgactt ccaagcctat actctatttt agtttatgct
    21301 tactttgtta tgtgaaactt agtaaagcat aaaagtagga ctagcgatat ctcttctgtt
    21361 tcagccatat atcactagcc ttacttaatt tgttccctat ttttctaaat actctttaat
    21421 gtcccgatat tccttagaaa aatccatcca cccgctaata tcagggttta agaatggtag
    21481 gacagtaagc ggacttactt ccgttcgata tagcgataga gaatgtttct gacttatttc
    21541 cctgactaca cctgtatgaa tttcttctac atccttcttt agttcttgaa tttcatcata
    21601 tgcgtccaga attcgtctaa gtttctttcg gtattgttta tagatcttct tagtttccat
    21661 ccgttgctta gtttctttaa aaatgtattc aaagatgact gctttagctt ctgaaaaatc
    21721 actattatat ttttcctgaa gagaattaat agctttttcc atcttttcca gcttttctaa
    21781 agattctaag ttatttgaca aaaaagaatt tatattctca aatgaaactg tttgaatgcc
    21841 taaaagactc ttcctttttt cgcttaactg ttctcgtgct gaataaatct tacttttttt
    21901 attatctaaa tcatccagtg tatcaaatac ttgattaata tccatttctt cctcctagtt
    21961 ccattgaata aagtaaccac aatcttcttc aacttttttt acatcaaatc gggtatgtaa
    22021 aatcaaccgt tttctaaaat agtcattcgc attcacccaa ctaagtgtat ctttctttcg
    22081 atcaaacaaa gtaacaaagt tttctagatc tccgataaat ccttttttgt cgccttcgtt
    22141 ccctaatgtc gtatcatcta caattaaaaa gttatctaca aagaatgttt cactcgttcc
    22201 tgtctcttta tcaactttaa gaagataatt tcctgaagtg tctttcattt tttctaagac
    22261 actaaatagt gattgactaa taactataga tacattgcgc tctggattga ttaaagaaac
    22321 aatagatttc aagtcgtcca gacttgtagc ggtctgtact ttcgcagttt ggagaatttt
    22381 cccaatctct ctatttcgtg ttctacgttt taatttaata atcttcttac caagaaaatc
    22441 cgttaaatta tattggccat catctaattg ttcctgtgaa aaatcaagtt ttccactgaa
    22501 taatttaact aagtaatcaa cgctgatagt tttcttttta tctgattctg ttctctcaac
    22561 aaaattttca ctaatttctt gtaatgaatc agattcaaag tcagttacct catacttccc
    22621 gccacgggta cgagtctcaa taacatttac tagatcaacc agttctttac gttgatgttc
    22681 atcttcgtaa ctatcaagga ttggtttttc aatgagtaca tgattatttt ctacattcat
    22741 ccctctagtg ttataacctg tacttcggat ataagcttct aaattttctt tttgtttaac
    22801 taagttagtt gtcatttttt tgctccttca tcttttaata tctgattttt gtttataatt
    22861 ttttctaaaa ttctttgctc ttagtttttc ttttatgact ctccgagcct ttagaatcat
    22921 tttttctaga ttttggtttg tcttgtttgt tagcatattt ctctagtatt tcttgtttcc
    22981 gttgttctaa gctatcacct tcttttttac actgagaaaa gattttctgt cttttatctg
    23041 gatccataga aaacttatca cctgcatacc atcacaaccg ccaatggtgg aagcaaaggt
    23101 ttaggcggtg gtgaccgcat tcaagccaca atggtatttg agaagattat ctaattaata
    23161 ccctttataa gttccataat cgcttcattt tcttacctgg tacattttac cgttcgttct
    23221 cttaaaatcg aaaatagagg ggttctcgta gctcctagca tggtataaac tcaaaacctt
    23281 ttctaattgc ttgcctgctg atggaaaaga atactatgca aataaaacaa atcacaaaaa
    23341 aagacggttc aatagtatat cgtgctaatg tctatcttgg tgttgataaa gtcactggaa
    23401 aagatgtaaa gacaagcata acaggaagga caaaaaaaga agttaagcaa aagacaaaag
    23461 aagctgaaat tgctttttta caaaatggat ctactagatt ccaggcttca aatattacta
    23521 cttacaagga attagcttcc ttatggtggg aaagttacaa gcatacagta aaacctaaca
    23581 cacaattaaa cgttagaaga ctgctagata accatatctt acctttattt ggctcttata
    23641 agttggataa actaactact ccacttattc aaaatatagt caataaactt gctgacaaaa
    23701 ccaataaagg ggaagaaggc gcttttctat actacgatag cttacacgct ttaaataagc
    23761 gtattttaca gtatggtgta gttatgcaag ctataccgtt taattctgct cgtgaggtaa
    23821 tattacctcg caacacacaa aaagcaaagc gagaaaaagt aaagcacttt gataatgacg
    23881 aattaaaaag ctttcttaaa tacttagata ctctggatct aagtaggtat cgctattatt
    23941 atgagattac actttataag tttctacttg ctactggttg tcgtatcaat gaagctttag
    24001 ccttatcatg gtctgatatt gacttagata atgctattgt gcatatcaca aaaacactaa
    24061 actataatca agaactcaat agtcctaaat caaaatctag ctatcgtgat atcgatatag
    24121 atcaagcgac tgttagtatg ctgaagcagt acaaacatag acaagtacaa gaagcttggc
    24181 aacttgggcg ctctgaaact gtagtctttt ctgacttcat aaatgagtac cccaataatc
    24241 gaactctaca aaccaggtta agaactcact ttaaacgtgc tgacgtacct aacattgatt
    24301 ttcatgattt tcgccatact cacgctagtc tcttgcttaa ctctggaata ccttacaagg
    24361 aacttcagca ccgtctagga cattcccaat tatctatgac catggatata tacagtcacc
    24421 tctcaaaaga gaatgcaaaa aaagcagttt cgttctatga aactgcacta aaaagtttat
    24481 aactgaacaa ataactgaac aaacccagaa atcaacattt taagacaaag caaaaagccc
    24541 actgttgtag gctttctgta agatatttct taaaattaaa gcattttgtt gtagaattca
    24601 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
    24661 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
    24721 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
    24781 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
    24841 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
    24901 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
    24961 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
    25021 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
    25081 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
    25141 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
    25201 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
    25261 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
    25321 tcctgctgat atttcacaca aaatctattc taccatgaat agctggattt gtaaaggggt
    25381 tttaggcttt attttcacta ccagagaggt tgagaacgag ggtaaaggta cttcctagac
    25441 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
    25501 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
    25561 gtttgaaaat attttccaaa tcctctgggg caataccctg cccttcatcg gtcacactga
    25621 ttgaaagctg gtccttctcc agcttagcca ccacttccag cttggttcct ggagcagaat
    25681 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
    25741 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
    25801 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
    25861 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
    25921 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
    25981 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggagtct
    26041 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
    26101 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
    26161 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
    26221 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
    26281 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
    26341 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
    26401 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
    26461 atatcccaac ccccaaactg tcttaatagt gggagtttgg tcactactat attttgccag
    26521 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
    26581 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
    26641 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
    26701 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
    26761 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
    26821 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
    26881 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
    26941 atcataacca tccatccgag gcatcatgac atctgtgata atcaaatcaa tcggtttttt
    27001 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
    27061 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
    27121 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
    27181 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
    27241 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
    27301 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
    27361 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
    27421 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
    27481 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
    27541 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
    27601 ctgtgtctga tgtttcttta acatttatct taatagtgac ttttttagtt gctacgatgt
    27661 tgtccaagtc tggtttaccg tctttgttac catagacatt gactgtagcg ctgtaagttt
    27721 gagtaccgtt tgctcggaac tggtcaatga gcgcttgttt ttctttgcca gctacatttc
    27781 cgtccaaggc ta
//
LOCUS       DBEJNA010000031        25049 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEJNA010000031 DBEJNA010000000
VERSION     DBEJNA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.31"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(172..3348)
                     /gene="carB"
                     /locus_tag="ACL3JB_001504"
     CDS             complement(172..3348)
                     /gene="carB"
                     /locus_tag="ACL3JB_001504"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0686214.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEVPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3660..4739)
                     /locus_tag="ACL3JB_001505"
     CDS             complement(3660..4739)
                     /locus_tag="ACL3JB_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0686215.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4789..5712)
                     /locus_tag="ACL3JB_001506"
     CDS             complement(4789..5712)
                     /locus_tag="ACL3JB_001506"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0686216.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5731..6252)
                     /gene="pyrR"
                     /locus_tag="ACL3JB_001507"
     CDS             complement(5731..6252)
                     /gene="pyrR"
                     /locus_tag="ACL3JB_001507"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0686217.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6463..7092)
                     /gene="nth"
                     /locus_tag="ACL3JB_001508"
     CDS             complement(6463..7092)
                     /gene="nth"
                     /locus_tag="ACL3JB_001508"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0686218.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(7092..7634)
                     /locus_tag="ACL3JB_001509"
     CDS             complement(7092..7634)
                     /locus_tag="ACL3JB_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0686219.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFASLQGLFDGDE"
     gene            7804..8121
                     /locus_tag="ACL3JB_001510"
     CDS             7804..8121
                     /locus_tag="ACL3JB_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0686220.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            8360..9919
                     /locus_tag="ACL3JB_001511"
     CDS             8360..9919
                     /locus_tag="ACL3JB_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0686221.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9963..10862)
                     /gene="htpX"
                     /locus_tag="ACL3JB_001512"
     CDS             complement(9963..10862)
                     /gene="htpX"
                     /locus_tag="ACL3JB_001512"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0686222.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10864..11424)
                     /locus_tag="ACL3JB_001513"
     CDS             complement(10864..11424)
                     /locus_tag="ACL3JB_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0686223.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11518..12231
                     /gene="rsmG"
                     /locus_tag="ACL3JB_001514"
     CDS             11518..12231
                     /gene="rsmG"
                     /locus_tag="ACL3JB_001514"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0686224.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12534..13817
                     /locus_tag="ACL3JB_001515"
     CDS             12534..13817
                     /locus_tag="ACL3JB_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0686225.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14012..15583)
                     /gene="ffh"
                     /locus_tag="ACL3JB_001516"
     CDS             complement(14012..15583)
                     /gene="ffh"
                     /locus_tag="ACL3JB_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0686226.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15595..15927)
                     /locus_tag="ACL3JB_001517"
     CDS             complement(15595..15927)
                     /locus_tag="ACL3JB_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0686227.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(16017..16394)
                     /locus_tag="ACL3JB_001518"
     CDS             complement(16017..16394)
                     /locus_tag="ACL3JB_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0686228.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            16466..17770
                     /locus_tag="ACL3JB_001519"
     CDS             16466..17770
                     /locus_tag="ACL3JB_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0686229.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17783..18589
                     /gene="yidA"
                     /locus_tag="ACL3JB_001520"
     CDS             17783..18589
                     /gene="yidA"
                     /locus_tag="ACL3JB_001520"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0686230.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            18632..19630
                     /locus_tag="ACL3JB_001521"
     CDS             18632..19630
                     /locus_tag="ACL3JB_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGR0686231.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(19797..19868)
                     /locus_tag="ACL3JB_001522"
     tRNA            complement(19797..19868)
                     /locus_tag="ACL3JB_001522"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19833..19835),aa:Arg,seq:cct)
     gene            complement(19910..20257)
                     /gene="rplS"
                     /locus_tag="ACL3JB_001523"
     CDS             complement(19910..20257)
                     /gene="rplS"
                     /locus_tag="ACL3JB_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0686232.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(20376..20705)
                     /gene="crcB"
                     /locus_tag="ACL3JB_001524"
     CDS             complement(20376..20705)
                     /gene="crcB"
                     /locus_tag="ACL3JB_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0686233.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(20699..21073)
                     /gene="crcB"
                     /locus_tag="ACL3JB_001525"
     CDS             complement(20699..21073)
                     /gene="crcB"
                     /locus_tag="ACL3JB_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0686234.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFVVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(21070..21336)
                     /locus_tag="ACL3JB_001526"
     CDS             complement(21070..21336)
                     /locus_tag="ACL3JB_001526"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0686235.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(21452..21895)
                     /locus_tag="ACL3JB_001527"
     CDS             complement(21452..21895)
                     /locus_tag="ACL3JB_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0686236.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRIFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            21999..22934
                     /locus_tag="ACL3JB_001528"
     CDS             21999..22934
                     /locus_tag="ACL3JB_001528"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0686237.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            23030..23272
                     /locus_tag="ACL3JB_001529"
     CDS             23030..23272
                     /locus_tag="ACL3JB_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0686238.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(23329..23907)
                     /locus_tag="ACL3JB_001530"
     CDS             complement(23329..23907)
                     /locus_tag="ACL3JB_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGR0686239.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(23882..24893)
                     /locus_tag="ACL3JB_001531"
                     /pseudo
     CDS             complement(23882..24893)
                     /locus_tag="ACL3JB_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(24896..25049)
                     /locus_tag="ACL3JB_001532"
                     /pseudo
     CDS             complement(24896..25049)
                     /locus_tag="ACL3JB_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         7480 a         5556 c         4691 g         7322 t
ORIGIN      
        1 tttttgaaaa atcttgatat gatgcgtttt ataattttaa agactttttt ctatagtaga
       61 ttgaaataag atgcgaacaa atcaattaga aaattcaaat taatttctag aaatatttta
      121 gtatccctgt gtactgttct aaattcagtc tgctatacct tatttttcta tttaaatcgc
      181 ttctgtaaca aagctacgac tttcaagtac cttaagcatg gcattagctg tatctagcgc
      241 tgtgaagagg ggcaccccgt gttcaatggc tgaacgacga atttgctcac catcttcgtc
      301 agcagttcgt tttgttccta ctgtgttaat gatagcttga attcttcctt tgcgtacaaa
      361 acttgggata tccttatcgt catcaccaat cttaccaaca ggttgggctt gcaagccatg
      421 actagcaaag aaggctgctg tcccttctgt cgcaaggatt ccataaccaa tgttttggaa
      481 acgacgagcc aagttcaagg cttcttcttt ggcatcatca gcgatggtaa agacgacatt
      541 accaaaagtt ggcaagtgta gataagaagc ttcaaaggct ttatagagag ctttttccaa
      601 agtagcatca gaacccataa cttcacctgt tgacttcatt tcaggaccga gcaagctgtc
      661 taccttagct agtttggtaa aggagaagac aggtgccttg atatgaacac gggtgctttc
      721 agggtaaagt ccattttggt agccaagttc tgataaactt tgaccaagaa tgagcttggt
      781 cgctacttga gccataggaa tattggttac cttagatagg aatggaacgg tacggctggc
      841 acgtggattg acctcaataa cgtagacttt ttcatccttg ataacaaact ggatgttcat
      901 cattccaagg cagtgaagac cgattgctaa gcgtttggtg tagtctgcga tggtctcctg
      961 aaccttttgc gacaaggttt gtggtgggta aacagccatt gagtcacctg agtggacacc
     1021 agcacgttcg atatgctcca tgataccagg aatgagtaca tttttaccat ctgaaatggc
     1081 atcaacttcg cactcttgcc caacgatata agagtcgaca agaactggat ggtctggact
     1141 agccttaaca gcagttcgca tgtaagaacg aaggtcttct tcgttttcaa cgatttccat
     1201 ggcacgtcca ccaagtacat aagatgggcg gacaagaact gggaagccaa tcttacgagc
     1261 tgcaagagct gcttcttctt cattggtagc cgtttgtcct ggtggctgtg gaatatccaa
     1321 ttctttgaga gcttgctcga agaggtcacg gtcttcggca cggtctaggt cagcaacctg
     1381 tgtaccaagg atggtcacac ctgcttttgc caatggctcc gcaaggttga tggctgtttg
     1441 accaccgaac tgaacgataa ctccctttgg ttgttccaag tcaatgacgt tcataacatc
     1501 ttcgaatgtc aatggctcaa agtaaagctt atctgataca gagaagtctg ttgaaacggt
     1561 ctctgggttt gagttcatga tgatagcttc ataaccagct gcctggatag ccttaacaga
     1621 gtgaacggtt gcgtagtcaa actcaacccc ttgaccgata cggattggac ctgaacctag
     1681 gacaagtaca gattctttat cagatctgat agattcattt tcccaaccat aggttgaata
     1741 gaaatatggc gtttcggagt cgaactctgc cgcacaagta tctaccatct tatagactgg
     1801 gacaatcttg ttttccaaac gaagttggcg aactttatca tcagtcgttc cccagagttc
     1861 agcaatctta cggtctgaaa aaccattaag tttggctgtt ttcaaaactt ctagatcttg
     1921 tggatgagca cccaattctt gctcaatttc aaagatatgc aagagtttat caagatagaa
     1981 gatatcaatt tttgtaagct ctgcaatttc ttcaggtgtg tagccacgac gaattgcttc
     2041 tgatacgtag aagagacggt catcttgggc tttgacaacc ttttcaatca aggcatcatc
     2101 agaaactgct gcaagttcag gtacttcatt gtggtgcacc ccaatttcaa gggatcggca
     2161 ggccttgaga agagattcct cgatgttacg accgattgcc atgacttctc cagtcgcctt
     2221 catttgtgta ccgagacggc gttcaccctt ttcaaacttg tcaaatggga aacgtggaat
     2281 cttagcaact acgtagtcaa gggctggttc aaacatggca taggttgaac ctgtaactgg
     2341 gtttataacc tcatccaagg tcaaacctac tgcaatcttg gcagccaact tagcaatcgg
     2401 atatcctgtc gctttagaag caagggctga cgaacgtgat acacgagggt ttacttcgat
     2461 aacataatac ttgaagctgt taggatcaag agctagctga acattacatc caccttcaat
     2521 cttgagggcg cgaataatgc tcaagctcgc atcacgaagc atttggtttt catagtctga
     2581 catggtttgc gcaggggcaa atacaatgga atcccctgtg tgaatcccaa ctgggtcaaa
     2641 gttttccatg ttacaaacaa ccaaggcatt gtcagctgag tcacgcatca cttcgtattc
     2701 aatttccttg aaaccggcaa tcgaacgctc aatcaaacat tgggtaacag gtgacaattt
     2761 caaaccattt tcagtgattt cacgcaattc tttttcgttg gcacacatac caccaccagt
     2821 accaccaagg gtaaaggctg gacgaacgat gactgggtag ccaattgtcg ctgcaaaggc
     2881 aactgcttct tctactgtgt taacaatttc agattctgga atgggttgct caagctcttc
     2941 catcaattgt ttaaagaggt cacggtcctc cgcttggtca atggcagata atttggtacc
     3001 cagaagttca acgccaagct cgtctaggat accattttta gataattcca tggccatgtt
     3061 gagacctgtc tgaccaccga gtgttggtag caaggcatct ggaccttcct tacgaagaat
     3121 acgtgtcaca aactcaagtg taatcggttc aatgtaaacc ttgtcagcaa tttccttgtc
     3181 cgtcatgatg gttgcaggat ttgagttaac caaaacaacc tcataacctt cctctttcaa
     3241 cgacaagcaa gcctgagtcc cagcgtagtc aaactcagca gcctgaccaa taataatcgg
     3301 accagaacca atcaccataa ttttttgaat atcagtacgt ttaggcatag tttatgatac
     3361 aaagcccgta aagaacacag tgaaaatagg aaactcggcg cagacgcctt cagcgtcaag
     3421 acgatgttta tctttttcac acagttctta gggcgtgttc acttccgcga acaatgtatc
     3481 ttctcctttc tattcgtcgc ctctcagggc gacattaaat aagatacaaa ggacgaatag
     3541 aaagcgattg aattttagga aatcaaggaa ggattgacaa tccaagttgg tttctctaca
     3601 ttctgagctt tccgtccgtg ttcagttaca taaattctcc gacgagcttt tactcgttct
     3661 tagtttgatt gtttaaaaac ttccatcatc tcgataaact cgtcaaatag gtagctagcg
     3721 tcgtgtggcc caggagctgc atctgggtgg tattgaacag agaaagcagg ttggtatctg
     3781 tggcgcacac cttccactga cttgtcattg atttcttcgt gggtaataat caagtgctct
     3841 ggcaaatcct cgcggctgac tgcataacca tggttctggc tggtgaagtc tactcgtcct
     3901 gttgcgattt cacgtaccgc atggttgaat ccacggtggc caaacttcat cttataggtc
     3961 ttagccccgt ttgccattgc aaagagttgg tgtcccatac aaataccaaa gattggaatt
     4021 tttccttgta caccgcgaat catgtcgagt gcttgtggaa cgtcttctgg gttacctgga
     4081 ccatttgaca acataactcc gtcaggattg agatggagaa tttcttcagc cgttgtcgaa
     4141 taaggaacaa ctgtcacgtt acagttgcgt ttagaaagtt cacgtaggat tgagtgcttg
     4201 agaccaaagt ccactagcac cacgctcaaa ccaactcctg gagctggata agacgtttta
     4261 gtagaaacct gtttgatatt gtctgtcggt aaaactgttg cttggagctg gtccgtcaca
     4321 tggtccatac tgtccccaac atgggtcaag gttgcacgca tagtaccatg cttacggata
     4381 atcttggtaa gagcacgcgt atcaattcct gaaatccctg gaattttctt ggctttcaaa
     4441 aattcatcca aggtcatttg gttgcgccag ttgctagctc tacgcgcttc ttcaaaaaca
     4501 acgactccct tacaagttgg aataatggat tcataatcat cacgattaat accataattt
     4561 cctaccaaag gataagtaaa ggtcaagatt tgtccattat aagactggtc tgtaatggat
     4621 tcttggtagc cggtcatccc tgtattaaag acgatttcgc ctgttacatc aatatctgct
     4681 ccgaaggcct tgccttcaaa aactgtgcca tcttctaata ctagaattct ttttgtcata
     4741 ttttcacctc tcgtggacgc tcactggcgt cttttaacgt cttgtgtttt agttggcgtt
     4801 tctactcgct agtacggatt ctaagattgc cattcgaaca aagacaccat tggtcatttg
     4861 ttggacaatc cgtgattttg gtgcttcaac caagtggtct gctatttcta catcacgatt
     4921 gattggagct gggtgcatga ggattgctgt ttctttcaaa cgatcgtaac gttcttgagt
     4981 caagccatgt tgggcatggt agtcttcttt tgaaaataca gctccactat catggcgttc
     5041 gtgttgcaca cggagaaaca tcatgacatc aacctgatca atgatttcat caatggttac
     5101 aaactgtcca tagtctgcaa actcttgact tctccattcc tcaggtccag cgaaaaagag
     5161 ttcagctccc aagcgtttca aaatctgcat attggatttg gcaacgcgtg agtggtccaa
     5221 gtcacctgca atagcaactt taagaccctc aaagtggcca aattcctcat aaatggtcat
     5281 caaatcaagc aagctctggc tagggtgttg gcccgaacca tctccaccat tgatgatgga
     5341 agtcgtaatc gttggactag caatcaattc tctatagtag tcgacctctg gatggcgaat
     5401 cacacagaca tccactccta aagcagacag agtcaaaatg gtgtcataaa gtgtctcacc
     5461 cttattaacc gagctagtct tcacatcaaa gtcaagtcgt tccaatccaa gtttaatctc
     5521 tgcgacttca aaggacttat gtgtccgtgt agaatcctca aagaagagat tggaaacaat
     5581 cggatggtct tcatagggaa gctgggctcc atttttaaac tcaattcctc gcttgatcaa
     5641 tttcattact tgatcgacag tgaggtcttc catggacacc acatggttca atgcttgttg
     5701 attttctgac atggctactc ctttaacttt ctaagcttct tcagtaatca gaactctgtc
     5761 ttggtcatca agttctgtca tctctacgat gatttcttca gaacgactgg ttgggatatt
     5821 ttttccaacg taatctggac ggattggcaa ttctctatgt ccacgatcga ctagaactgc
     5881 taaactcaca cgcgcaggac gaccatgacc gacaatatta tcaatagcag cacggatggt
     5941 acgacctgta tagagcacat catccaccaa gataacttcg cggtctgtca catcgacaga
     6001 aaccaaagaa gtatcttctc cacttttaac atcatcacgg aaaggtttag tatccaattc
     6061 cacaacagga actgaaagat tttctaactg cttcaaacgt tcttggattc ggtgggcaat
     6121 aaagacacca cgagttttaa taccagccaa gacgatctta ttcaaatctt tgttgcgttc
     6181 gataatctca taagtaatac gcgtaatcgc tcgtttgacg gtcaattcgt ctacaacttc
     6241 ttttgttttc atgacaaacc tccaaaaaga aaagtctcct taaacaagga gacttgaaat
     6301 ttatagccaa gcgagcccta ctgcacacag tatagacttc acccttctac tttatcgcgc
     6361 tccttgcctg cctcacggga caggtttaaa ggaatattta gttatcattt actatagcac
     6421 aaagcatgct taaaatcaag caaaaagttt caatgtagca tcttacaaat tgctaaaatc
     6481 atataattgt gggtactgat cacactctgg attttttgga tggcaaatgg ctcttccaaa
     6541 ataaatcatg gcctgatggg cagctaacca ctgctcaggc ggcaagatat ccatgacccg
     6601 cttttccacc tcaagtggcg tcgctgattt tttgacaata tcgtggtgtt tgcaaatacg
     6661 ctccacatga gtatccactg caaaggctgg aatcccaaat cctacactca tgacaacatt
     6721 ggctgtcttg cgaccaacac ctgccaaact ctccaattct tcacgtgtct gagggacttg
     6781 accatcaaaa tcgtctagta actgttgggc acatttttta aggaatttag ctttattccg
     6841 atacaatccc aagcgagaaa tatgtgaagc aatctcactc tctgtcgcta cagacatagc
     6901 ttggggtgtt ggaaaggcaa caaagagacc tggtgtggcc ttatttaccg ctgcatctgt
     6961 cgtctgggct gataacatga ccgcaaccag gagttcaaaa tgattggtaa aatcaagact
     7021 aggcttggca tctgggaaga gggcaatgat ttcttctagc acctttcgtg ctcgtttttt
     7081 tgacaagacc attattcatc tccgtcaaat agtccttgta agctagcaaa aggactgttt
     7141 tcttctttct ttactgcttg ttgagcttgg tattcttcct ctgtcatgat ttgccagtca
     7201 tttcctgaga caaatccttg accagcttct tcttcagccg tcaagacctt gataggaatg
     7261 tttagcagga tattgtctga tacactctca gcaaggtcaa gcgccccatt ttcgatgggc
     7321 aagaccaagt catcatctaa aatttcttga tttagatggt tagttgcgcc ttccatgaaa
     7381 acttccgtga ctggataaga ttcaactaac tcaactggct ccatactgcg actcgaagca
     7441 agaacaatgg tataagatag ttgataatct aagaaataca tacggtcttc atattgtact
     7501 ttcccaactg caaggatatc ttttacatct aaaatttctt gattacgtgc acgcaggtca
     7561 tcaactaaat ctaacgtttg ttcaaagttc aaaccttcag actgcttacg aatttcttga
     7621 atatttaatt tcatacttcc tccataaaga tttactctct tgattatacc atgaaaaggc
     7681 tacaaatcag cacaccaaac tttgtaatta aaattcaaaa ttttaacata tttaccatga
     7741 tagttttgtt ttttagtgct atactatagg gaaagagtac atcagatcaa ggaggatgct
     7801 cacatggaag acaagaaact cattcaactc ctatccaagt taaataaaag ctaccaaaac
     7861 tgtaaacagg gtacggcaga tgatattcga ctacaagagc tgctaaacac tactatgcaa
     7921 gagctcaaaa aaacggaaaa gttgaacaac agtatcttaa ttgatcttga gaaattttac
     7981 caacccacca gtcctctgat tggactgggt agcctaaaac taaacaatca agcacgcact
     8041 gcttggcgaa actatgataa aatccattac gagcatgtca aacacgtact aagtctctat
     8101 ggacctgttt ttggatttta gagcatagaa tttccagttt tctgttgaca aaatttcctt
     8161 aaaggtatag tataaagata ctaatactcg gaggtaaggg agacatgaac aactaagtct
     8221 atcaaataaa gaacctttat ttagtagatc ttgtttttgt ctctttttgt gtgctctttt
     8281 atgctctttt tctggcatgt taatagagtt tttttgacat agactttggg ctctactagg
     8341 taaagtagag ctttttgtta tgcactatga acattctaga aagggaaatc atatgataaa
     8401 aatcaatcat ctaaccatca cacaaaacaa agatttacga gatcttgtat ctgacctaac
     8461 catgaccatc caagacgggg aaaaggttgc tattattggt gaagaaggaa atggcaaatc
     8521 aaccttactt aaaattttaa tgggggaagc tttgtctgat ttcactatca agggaaacat
     8581 ccaatctgac tatcagtcac tggcctacat tcctcaaaaa gtccctgagg acctaaaaaa
     8641 gaaaacttta cacgactact tctttttaga ttctattgat ttagactaca gtatcctcta
     8701 tcgtttggcg gaggaattgc attttgatag caatcgtttc gcaagtgacc aagagattgg
     8761 caatctatca gggggcgaag ctttgaaaat tcagcttatc catgagttag ccaaaccctt
     8821 tgagattcta tttttagatg aaccttcaaa tgacctagac cttgagacag ttgattggct
     8881 aaaaggccag attcaaaaga ccaggcaaac cgttattttc atttcccatg atgaagactt
     8941 tctttctgaa acggcagaca ctattgttca cttgcgactg gtcaaacacc gtaaagaagc
     9001 ggaaacgcta gtagagcatt tagactatga tagctatagt gagcagagaa aggctaattt
     9061 tgccaaacaa agtcagcaag ctgctaacaa ccaaagagcc tacgataaaa ccatggaaaa
     9121 acatcggaga gttaagcaaa atgtagaaac tgcgcttcga gctaccaaag atagtactgc
     9181 cggtcgccta ttggctaaaa agatgaaaac tgtcctctca caagaaaaac gctacgaaaa
     9241 ggcagctcag tccatgactc aaaagccact tgaagaggaa caaatccaac ttttcttttc
     9301 agacatccaa ccattaccag cttctaaagt cttagtccaa ctggaaaaag aaaatttgtc
     9361 cattgacgac cgagttttgg ttcaaaaact acaactaact gtccgtggcc aagaaaaaat
     9421 cggtattatc gggccaaatg gtgttgggaa atcaactctg ttagccaagt tacagagact
     9481 tctgaatgat aaaagagaga tttcacttgg ttttatgcca caagattacc acaaaaaact
     9541 gcaattggat ttatccccaa tagcctatct cagtaaaact ggggaaaaag aggaactaca
     9601 gaaaatccaa tctcacctag ctagtctcaa tttcagttat ccagaaatgc agcatcaaat
     9661 tcgctcctta tctggcggac aacagggaaa actcctgctt ttggatttag tcctgcgcaa
     9721 accaaacttt ctcctgctgg atgaacccac acgaaacttt tctcccactt ctcaacccca
     9781 aatcagaaaa ctctttgcta cctatccagg cggtctcatc actgtttcgc atgaccgtcg
     9841 tttcttaaaa gaagtctgct cgatcatcta tcgcatgaca gaacacggtt tgaagctagt
     9901 taatttagaa gatttataaa tttgcaacat agcaaaaatc cagagacgac ctctggattc
     9961 ttttacatct gttttaaacg ttcaatccgt tctgagatag gtgggtgggt ataaaagagt
    10021 ttttggaacc ccccaccttt cttaggatca ttgatataaa gggcactgct agcatcatcg
    10081 acgtggcgac tcataggttt gctattgtcc aacttatcta gggcattaat cattccctgg
    10141 ggattgcgag tcagctcgac actagatgca tctgccagaa attccctctg acgagaaata
    10201 gcgagctgaa ccaaggttgc agcgagaggt gccagtacaa tagctagtag ggaaaccact
    10261 agcataatga tttcaagacc atttccatct cggtcatcat cacttcgtct gcgacctgct
    10321 ccaccccacc acatcatacg acctgccata ctagaaagca tggtgatagc actagcaagg
    10381 gcaactgcaa tagtcgaaat acggatatca taattacgaa tatgactgac ttcatgtccc
    10441 ataacagctt ctagttcttc acgattcatg atagctagta gacctgaagt cgcagcaaca
    10501 gccgcatttt gaggattaga acctgtcgca aaggcattta aggctggatc atcaatgatg
    10561 aaaacacggg gcataggaat ctgagcgacc agagccatat cttccactac atggtagagg
    10621 tctggtgccg tttgctcatc cacctcacgc gctccattca tggacatgac aatctctgtc
    10681 gattgaaaaa tcatagacaa agcgtagata aagccgataa tcagtgcaat aaccaaacca
    10741 ccaagtccag atcttataaa gagataacca accgcataac caacaagagc taagagtagg
    10801 aaaaatacca gcaacaaaat ccaggttttt cgtttattgc ttgcaatttg atcaaacaac
    10861 atcttagtca cctaaaccgc taaaatcaac tttaggaacc gacttttcct cttcaggtgt
    10921 ttgaaggaaa tctgccgctt taaatccaaa cattccagcg ataatattgc tcgggaaagt
    10981 ttctaatttt acattgtagt tgctgacaac actgttatag agttgacgag agtaagaaat
    11041 tttattttct gtgtttgtca actcctcttg caatttaaca aagttagcac tagctttcaa
    11101 atctggatag ctttctgcaa ctgcaaaaat acctgaaacc tgacgagtga gggcatcact
    11161 ggctttcata gcttctgctg gtgaagtcgc tgccgccact tggttacgta gttctgccac
    11221 cttttcaagg gtagaacctt catatttggc ataacctttt acagtctcaa tcaagtttgg
    11281 caagaggtca tttcgacgtt tcaactgaac atcaatctga ctccaagcct ccttggtttg
    11341 catacgattt ttaaccaaac cgttatagct aacaatcaca aaaataacaa taagagcgat
    11401 aactccaaga ataatccaag tcataatata agtcctttct gcttttagat tagtaccagt
    11461 atatcaaatt ttctatgatt gtggtaaaat aagatgatac taaagaagga aataactatg
    11521 aaaccaaaaa cattttacaa cttgcttgcc gagcagaatc ttccactttc ggaccagcaa
    11581 aaagaacaat ttgaacgtta ttttgagctc ttggtcgagt ggaatgagaa gattaatttg
    11641 acggcgatta cggacaagga agaagtttat ctcaaacatt tttacgattc gattgcaccc
    11701 attcttcaag gtttgattcc caatgaaact atcaaacttc ttgatatcgg ggctggggca
    11761 ggatttccta gtctaccaat gaaaattctc tatccggagt tagatgtgac cattattgat
    11821 tcactcaata agcgcatcaa cttcctacaa ctcttggctc aagaactgga tttgaacgga
    11881 gttcatttct accacggacg tgccgaagat tttgcccaag acaagaactt ccgtgctcaa
    11941 tatgattttg taacagctcg tgcggttgcc cgtatgcagg tcctatctga attgaccatt
    12001 ccctacctta aggttggtgg aaaactattg gcactcaagg ccagcaatgc gcctgaggaa
    12061 ttattagaag ctaagaatgc cctcaatctc ctttttagta aggtcgaaga caatctcagc
    12121 tacgccctac cgaatagaga tccgcgctat atcacagtgg tagaaaagaa aaaagaaaca
    12181 ccaaataaat atccgcgtaa ggctggtatg ccaaataaac gcccacttta aattttttag
    12241 taaacaaatg tttacaaaat cagcctcgct cttttatttc taggctcggg aaaaaatgat
    12301 ttacaaaatc agcctcgctc ttttatttct aggctcggga aaaaatgatt tacaaaatca
    12361 tttttttctg ctatactatc ctaagcaaag gtttttaatg tcatcccgtg aggtgacgaa
    12421 gacgcagaaa tatttgaaac tctttaaaat ctaaatttta aagaagtctt actctgaggg
    12481 cctattgctg taaaataatg ggctcttttt tgatgcccaa aagtgaggtt tatatgaaac
    12541 aagaatcaac tgttgatttg ttactagacg ttgaccaacg tccttcggat ggaaaaggaa
    12601 ttctccttag cttccaacac gttttcgcca tgtttggtgc gaccatcttg gtaccattga
    12661 ttttgggaat gcctgtatct gttgcccttt ttgcttcagg tgttggaaca ctcatctaca
    12721 tgattgctac tggttttaaa gttccagttt atctaggttc ttcatttgcc tttatcacag
    12781 ctatgtcact ggctatgaaa gaaatggggg gggatgtatc tgctgcccaa acaggggtta
    12841 tcttgactgg tttggtctat gtccttgttg ctaccagcat ccgatttgta ggaacaaaat
    12901 ggattgataa actcttgcca ccaatcatta tcggtcctat gatcatcgtt atcggtcttg
    12961 gacttgcagg ttcagctgtt accaatgcag gtcttgtagc agacggaaat tggaaaaatg
    13021 ctctggtagc cgttgttact ttcctaattg ctgcctttat caatacaaaa ggaaaaggct
    13081 tcctacgaat cattccattc ctctttgcca ttatcggtgg ttaccttttc gcactaactc
    13141 ttggcttggt tgactttaca ccagttctta aagccaactg gttcgaaatt cctggtttct
    13201 acttgccatt tagcacaggt ggtgccttta aagagtacaa tctttacttt ggtccagaag
    13261 ccatcgctat cttgccaatc gctatcgtaa caatttctga acatatcgga gaccatactg
    13321 ttttgggtca aatctgtggt cgtcaattct taaaagaacc aggtcttcac cgtactcttc
    13381 ttggtgacgg tatcgcaact tctgtttctg ccttccttgg tggaccagcc aatacaactt
    13441 acggagaaaa tacaggggtt atcggtatga ctcgtatcgc ttctgtctca gttatccgta
    13501 acgctgcctt catcgcgatt gccctcagct tccttggtaa attcactgcc ttgatttcaa
    13561 ctattccaaa cgctgtactt ggtggtatgt caatccttct ctatggggtt atcgccagca
    13621 atggtttgaa agtcttgatt aaagaacgtg ttgatttcgc tcaaatgcga aacctcatca
    13681 tcgcaagtgc tatgttggtt cttggacttg gaggagctat ccttaaactt ggtccagtta
    13741 cactttcagg tactgccctt tcagccatga caggaatcat cttgaacttg atcttgccat
    13801 acgaaaataa agactaagag tctaaataca cctaatccac tcagacagct gagtggattt
    13861 ttcgtatatc ataataaaag tgtcttaaca aaattattaa aatcaaaaaa cgtataatat
    13921 cagatattct aaaaccttga tactgtacgt tttatcatag aaatttttac tttattttct
    13981 catcaaatga gatttgcatc aatctcttgt cttacttgcg tttcttcttc gctttcttca
    14041 ttttgttagc catacgtttc atggactgtt tcatggcaaa ttcaccaatt ttacctttca
    14101 aaccgccacc aaacatctgg ctcatatctg gcattcctgc tcctccgaga gctgataagt
    14161 caggcatacc gccttgtccc atcattcctt caagggcaga catatccatt cctcccatat
    14221 ttggcatatt tttaggaagg ttatttggat taatccccat ttgcttcatc attttattca
    14281 tatccccaga cataacaccc tgcatgagct gtttagcctg gttaaagtcc ttgataaatt
    14341 tattgacttc gacgaatgta tttccagaac cagcagcaat acgacggcga cggcttggat
    14401 ttaacaaatc tgggttttca cgttcttcag gtgtcatcga agacacaatg gcacgtttac
    14461 gagcaatctg gcgttcatcc accttcatgt tttgaagtgc tggattgttg gccatacctg
    14521 gaatcatctt gagcaagtct tccatcggcc ccatattttg cacctgatct aattgatcga
    14581 tgaaatcatt aaaatcaaag gtgttttcgc gcatcttctc agccatttca agggcttttt
    14641 gttcatcgta ttcctgagaa gctttctcaa tcaaagtgag catatccccc atgccaagga
    14701 tacggctaga catacggtct gggtggaagg tttcgatatc tgtaattttt tcacctgtac
    14761 cagtgaactt gattggtttt ccagtgatgt gacgaaccga tagagccgca ccaccacgag
    14821 tatcgccatc aatcttggta aggatgaccc cagtcacttc caactgagca ttaaactcac
    14881 gcgcaacatt ggctgcttcc tgaccaatca tggcatcaac gacgaggaga atttcatttg
    14941 gttgagccaa tgctttcaca tcacgaagct cattcatgag gagctcatca atttgcaaac
    15001 gacccgcagt atcaatcaag acatagtcgt tatgattagt ttgggcttgc tccaaacctt
    15061 gacgtacaat ctcaacagct ggtacttctg ttccaagtgc aaagacaggc acatcaatct
    15121 gttgtcccaa ggtcttaagc tggtcaatgg cagctggacg ataaatatcc gccgcaatca
    15181 tcaaaggacg agcattttct tctttcttga gtttgttggc caatttacca gcaaaggttg
    15241 ttttaccagc cccttgtaaa ccaaccatca tgatgatggt tggaatctta ggtgacttga
    15301 taatttctgc cgtatcagaa cctaaaacgg ctgtcagttc ctcatcaacg attttaataa
    15361 tctgttgcgc aggattaagt gtatcaatga cctcatgccc gactgcacgc tcacgaactt
    15421 tcttgataaa gtcctttaca acaggcaaag caacgtcggc ctcaagcaag gccaagcgaa
    15481 tttctttggt tgcctcttgg acatcagact ctgagatttt tcctttttta cggagatttt
    15541 taaagacgtt ctgcaaacgt tctgttaaac tttcaaatgc catgtttctt cctcttattc
    15601 tctattatca atgcttgtta aaatttctat ctgctcctgc agaaaatcat ccttgggata
    15661 gcgctccaag atttggtcaa aaatctgact acggacaatg tagtccgagt acatgtgcaa
    15721 tttcatctca taatcttcca gaatcttttc tgttcgcttg atattgtcat agacagcctg
    15781 acgactaaca ccaaactcct cagctatctc agcaagactg taatcatcag cgtagtaaag
    15841 ctctatataa ttcatttgct tatctgtcaa aagcgccgca taaaattcaa agagcgcatt
    15901 catacgattg gttttttcga tttccataac ttttattata ccaaaaaata gcctaatcta
    15961 ccacactagg gagccaatcc ttgaagatag aaagtagatt tgagaaaaac gagatcctag
    16021 ccccaagtaa tttccaattg atagctggca aagggatgcc cctcttgatt ttgtagttga
    16081 taagctagct caatcttttg cccatctact tgataacggc tcgtttgaat gataaattcc
    16141 tgcatgccca taggggtagg aatataggcc aaactatcac tatcctttaa aaagcgcata
    16201 atggtcttgg gattggaaaa tcggctcatc accagttctt gaccatgaaa tttaataact
    16261 actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt ttcatgcact
    16321 tccacatcat aaagctggtc aatcacttcc aactgctcat caaactgaat tgtatttcgc
    16381 atccgaatct tcacatcagg tcctctttct tgtctcttgt cctactattt taccaaaaag
    16441 agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc cagttcacaa
    16501 ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag aatttcagcg
    16561 tttgcgccgg atcaaacaac tgggaacttc cagttatacc ttccacggtg gagaacacag
    16621 tcgcttctct cactgtctag gagtctatga aattgcacga cgcatcacag agattttcga
    16681 agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga ccgctgctct
    16741 cctacacgac cttgggcatg gtgcctactc ccatactttt gaaaatctct ttgatacaga
    16801 ccatgaagcc attactcagg agattattca aaatcctgag acagagattc accaagtcct
    16861 gctacaagta gcgcccgatt ttccagagaa agttgccagt gtcatagacc atacctatcc
    16921 taacaagcag gtcgtacaac tcatttctag tcagattgac gcagatcgca tggactatct
    16981 cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga ctcgcatcct
    17041 ccgagtcatt cgtcctgtcg aaaatggtat cgcctttcag cgcaatggca tgcacgccat
    17101 cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc acccagcaac
    17161 acgcgccatg gaagttctcc tacagaatct tctcaagcgc gccaaggaac tctatcctga
    17221 ggacaaggat ttctttgccc gaacttctcc acacctcctg cctttcttcg aaaaaaatgt
    17281 gaccttgact gactatctgg ctctggatga tggcgtgatg aatacctact tccagctttg
    17341 gatgaccagt cctgacaaga ttcttgcaga tttatcgcat cgctttgtca accgcaaggt
    17401 ctttaaatcc attacctttt cacaagagga ccaagatcaa cttactagca tgagaaaatt
    17461 ggttgaggat atcggctttg atcccgacta ctacactgcc attcataaga actttgacct
    17521 cccttatgat atctatcgtc ccgaatctga aaacccacgg acacagattg agattttaca
    17581 aaaaaatgga gaactggccg aactctctag cctgtctctt atcgtccaat cccttgctgg
    17641 cagtcgccac ggagataatc gtttctattt ccctaaagaa atgttagacc aaaacagcat
    17701 cttcgcaagc attacccagc aatttttaca cttgattgag aacgatcatt ttaccccaaa
    17761 taaaaactag aagaggaatt ttatgagtat taaactaatt gccgtcgata ttgacggaac
    17821 cctagtcaac agccaaaagg aaatcactcc tgaagtcttt tctgccatcc aagatgccaa
    17881 agaagctggt gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg ttgccaaact
    17941 tctggacgac ttgcagttga gagaccaagg tgactatgtg gtgaccttca atggtgccct
    18001 tgtccaagaa actgctactg gccatgagat tatcagcgaa tccttgacct atgaggatta
    18061 tctggatatg gaattcctca gtcgcaagct cggtgtccac atgcatgcca ttaccaagga
    18121 cggtatctat actgcaaatc gcaatatcgg aaaatacact gtacacgaat caaccctcgt
    18181 cagcatgcct atcttctacc gtacccctga agaaatggct ggcaaagaaa ttgttaaatg
    18241 tatgtttatc gatgaaccag aaattctcga tgctgcgatt gaaaaaattc cagcagaatt
    18301 ttacgagcgc tactccatca acaaatctgc tcctttctac ctcgaactcc ttaaaaagaa
    18361 tgtagacaag ggttcagcca ttactcactt ggctgaaaaa ctcggattga ccaaagatga
    18421 aaccatggca atcggtgatg aagaaaatga ccgtgccatg ctggaagtcg ttggaaaccc
    18481 cgttgtcatg gaaaatggaa atccagaaat caaaaaaatc gccaaataca tcaccaaaac
    18541 aaatgacgaa tccggcgttg cccatgccat ccgaacatgg gtactgtaaa agtatcattt
    18601 ttcaataaga attgattagc aataaaatcc aatgaatttt tttagcaaac tatttaattt
    18661 aaaacaaaat aatcataata gagacacaaa ttctgattgt aacaattttt acctaaacga
    18721 attagaatgt ggccttactc ctgggcaact catactcata gattggactc aaaaaacagg
    18781 gagaaattat aatttcccaa gatattttaa atactctctt caaattgacc ctgaatctac
    18841 acacaatcaa ttatacaaat taggatactt cactaaaaat aagactttat catatcttac
    18901 agtagtagaa ttaaaaacta tattatctaa acataattta gctacttctg gaaaaaaagc
    18961 agaattaatt acaagaataa ttaataatgt taacattgac aatttagata ttccgttcga
    19021 atttaaacta acaaaagaag cacaaaatct tattatcgaa catagtgact atatcaaagc
    19081 atactatgat aaagacataa ctatggaaga ttattgtaaa gaaaaaaaca atatctcttt
    19141 taaagcaact tttggtgata taaaatggag tctcttaaat aaacaagctc ataggaatac
    19201 tgtatcagga gattttggat gcttatctaa cacacgaaag gctcagggaa gacatttgga
    19261 acaagaaggt aatattaaac atgctttaat atattacata gaatctttga taattactat
    19321 ttcaggatta gaaaacaatt tttcagccac tgattatcca gtatattatc ccgattcgat
    19381 acctgactac tcactaaaac atattcaaac attaatggaa tcattatctg atgacgatta
    19441 tgattttgct tttgatgaag cattatttcg cttctcaatt ttgaatgcaa atcatttttt
    19501 atctaaggaa gatattgact atttaagagt taatttacct cgttccactg ctgaagaaat
    19561 aaacaattac ttaaagaaat atgaatgtta tagtccttta aataatttag aacttgacga
    19621 ttttgaataa attgactata caaacattta tatactcgat atagtctcaa ttttatctga
    19681 tgattgccca aatttttcaa taataaaacg cataatatta tggagacaat cccctatatt
    19741 atgcgttctt ttaatatcaa agactttttg acaaacttct ttgatatcta attacatgcc
    19801 ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat ccattgaact
    19861 aagggagcta gataaaaact ctgctgaaaa gcagagtttt ttagtcgaat taacgacgga
    19921 tttctttgat acgagctgct ttaccttgaa gagcacgcaa gtagtacaat ttcgcacgac
    19981 gtactttacc gtaacgaaca acttcgattt tttcaacacg tggagtgtgg attgggaaga
    20041 tacgctcaac acctacaccg ttagagattt tacgaactgt gtagttttct gagattccag
    20101 cacctttacg tgcgataaca acaccttcaa aaatctggat acgttcacgg ttaccttcga
    20161 caactttcgc gtgtacacga acagtgtcac caggacggaa tgatgggata tctgtacgaa
    20221 gttgaccttc agtcaagctt tggattaatg gattcatttt attctcctat ctttgtcaat
    20281 cttgaggaaa cttcctcagc ggataaactg tattcttgtg cgtccattac acacaagata
    20341 cagtttacca aattttcaca aaaaagtaaa gaaatttata gcaaaattcc taaaaaaatc
    20401 gcaaccaaac cacctatgta agtcaaagtc aggtaagaat aaaagacctt cttatcactt
    20461 agcagtcttt gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc acaaaatcct
    20521 gttgctagaa tagcatatac ttccttagac tctacatgat tgtagaatac tccaattaaa
    20581 aaacaaccta aaagattagc tatgagcgtt ccgagtggca atttagaagc ttgattatag
    20641 cgagaaaaga aataccgtac gagtgctccg aaaccacaag caattgcaag atagacaatt
    20701 accatttctt cctccctaga aaataagcta agagtaggcc tccaccgatg ctcaaaagca
    20761 aatacaggac taaactaaaa taacgccctg tatcaagcag cttcacagta tcaagcatta
    20821 ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa atcaagccct
    20881 tactagtccc cttatagacc agatagccct tgacaacaaa aatcaagcag aaaattccca
    20941 gatagttgac aaagagagtg ccccaaggaa agtctggact ggctggtaac caggtggaaa
    21001 ctagatatcg gacaagtccg cccaacatag cagctagaaa aattcctagc ggataaaatt
    21061 gttctttttt catttgatat tttgatcctg ataatcacgc gaacgtttga gtatgtccga
    21121 aaaagtcgct acaatagtct cctgatagcg cttgtcctct acacgactcc taaccttttc
    21181 aaaaataact tcttctctct tagtatctaa aatcggttta cctgaagctt tcttataagc
    21241 aaccaccccc tcaactaaat gcattcgttc ttctaacagt ttgacaattt ggtcatcgat
    21301 ttgatcgatt tcttgacgaa taatatctaa atccatacag tctcctcctt tatttgaatt
    21361 attgtatcaa aaagccatca attaggctag taaaatccca actctcgata agaaaaatgc
    21421 actgattgat tacatcagcg cacttttatg cttatactac tttagcaacc aattcttctg
    21481 cgaattgttc caagcgttca atatcttctt cctcggcaga aagatcaact ttgacacact
    21541 cagaaccttt ttctgctcct gttgacacaa agatacggtc aaagtcatca acagccttac
    21601 agaattcatc gtagaaggta tctcctgagc cgaccactcc gtagattttg ccattcaagt
    21661 tgagatctgc taggtcttcg tagaagtcca tcatctcatc tggcaattca ccatcaccat
    21721 aagtataggt cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg tcaacagttg
    21781 tacattcatc aacatcaaca tccaagccca agtcacgtaa tttgtctgct acaatatctg
    21841 caatttcttc ggtattaccg gtcatactgg caaatacaat ttttgctaat gccatatcgt
    21901 cctcctcaat ttatctttct ccattatatc acatcttttt cattttaaaa ataaaaattc
    21961 ttgtgctaca atgaaatgag aaagaattga ggttatttat ggagatttgc caacaaattt
    22021 tagaaaaaat taaagaatac gacaccatta tcattcatcg tcatatgaaa ccagaccctg
    22081 atgccttggg aagtcaggtg ggattgaaag ccttgctgga acatcatttc ccagaaaaaa
    22141 ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg gatggctgag atggatcttg
    22201 ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg tgatacagct aatactgctc
    22261 gtatcgatga taagcgctat agtcaaggtg attttctcat taagattgac caccatccaa
    22321 atgatgatgt atacggtgac ctgtcttggg tcgatactag ttcaagtagc gctagcgaga
    22381 tgattaccct atttgcccaa acaacccaac tagccttggc agatcgcgat gctgagttgc
    22441 tctttgcagg aattgtcggt gatacaggtc gcttcctcta cccttctacc actgcacgga
    22501 ctcttcgcct ggctgcttat ttgagagaac ataactttga ctttgcggct ctcactcgca
    22561 aaatggacac tatgagctac aaaattgcta aactgcaagg ctacatctac gaccatctgg
    22621 aagtggatga aaatggtgct gctcgcgtta tcctgagtca agaagtcttg aaacaataca
    22681 atgtaaccga tgctgaaact gcagccattg tcggtgcacc tggacgcatt gacagagtga
    22741 gtctctgggg aatttttgtc gaacaggctg atggccacta ccgagttcgc ttacgcagta
    22801 aaatccatcc tatcaatgaa atcgccaagg agcatgatgg tggaggccac cctctagcaa
    22861 gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag ttaaaaaact
    22921 tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa tctgatagac tagtatggta
    22981 acaatctatg gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa tgaaaaaaga
    23041 tatccatcca gaatatcgcc cagttgtctt catggacaca actactggtt accaattcct
    23101 tagcggttca acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa cttacccatt
    23161 gatccgtgtg gaaatttcat cagactcaca cccattctac actggacgtc aaaagttcac
    23221 tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat aatgataaaa
    23281 gaacagtttc ggctgttctt ttttgtttct tgaaatcaac tgctgttttc atgttccaga
    23341 ctcatctgta ggttcggttt ccatgctact aggcaggaag gaaatagctg tttcaacacg
    23401 tccataatga gctgtactat tgtcacgaac cacactttca ttgatggtcc aagtggaatt
    23461 cattttctta aaagcttctc ggactttttc caaatctttg gaggcaatgg cctgctctaa
    23521 ggtttcaaaa cgaggactta gacggtttac caatttttcc ttttccgcat ctaggtcaac
    23581 aggattttgt tctttttcaa aagctaatag agctgaggaa atttcggtga gtttggcttc
    23641 agtaatatct ccagatagag ctaacttttc cttaacaatc ttaccaacct cagaatcctt
    23701 attttctact ctttcgaagt ctgatgccat cttcgtaacg agtttctggg tctcagtctg
    23761 accaccattt ttaaccgctt tggatgcatc tgtgattttc acaaagaaaa aactcaagct
    23821 ttcttgggca cctgctgggg aaagaattaa aaatgacaaa gctaaaacta gtaaccagct
    23881 tttagccttc caataatttc tgaccaatgt agcctccttt ctccacacca ccaaagcaag
    23941 taaaaagtcc actacctatg tgagtgatgt attcattcat cttatcagta gcacctaggt
    24001 tagtttgaac cttaacaaag ttatcaggat ccttctggaa agaaatgaag agcaatcccg
    24061 tatcaaactg accagtcttt tcatcaatgc catctgagta agagtaagaa caacgcaaaa
    24121 gtggcttgtc cacttactta gccaaacgaa catgcgaatc atctagcaaa aaactcaaat
    24181 tcacttcatc aaactcattt ttttaccgaa aggggcacta ctttccttgt aacgaccaaa
    24241 ggtattttct tgttcttcga gaccagtgcg gtcccaggtc tctaaaaaca tctgaatccg
    24301 acgaactgcc atataagaac cattttccat ccagtcctta ctatcagccc agataacgcg
    24361 gtcaaagtct tgctccttgg ttgaatttgc tgttccatcc ttaaaaccaa agaggttcca
    24421 cggagtctcc attcgtcccc gatagctgca aatccagact gactccaacg aaggggcacc
    24481 gcatttctcc ccttacgtat gagattgcga ataacgtgaa aggcaatttg ctcatcatct
    24541 gcacaagcat gaatcacaat atctccacca gtatattttt cacgtaattg ctccttagga
    24601 aatagaggta aatccctgaa cagtcgaggg cgcttgtttt ccaagttcat ctttttcaag
    24661 aaacttgcag atacaccaaa agtcagcgtc aaacgatgag gattgagccc aactgtctca
    24721 ccagtatcgc tcggaggaaa gagagcattc tgtccatctt ttttaaccaa ttccccctcg
    24781 accaacttgg cactataatc cgtccaatcc ttgaatagct ggataatttt atctctatcc
    24841 gtcgtatgca ggtccaagac aacaaaatag atattctttt gcatgggcgt actatttggt
    24901 acatcaagcg aaccttacga aaacgtctac tatatttaaa ccgctttctt gtcttcttga
    24961 attgagattt tatttttaga cgcgacaatg gtttgagcgt ctgctttctt aggatgttct
    25021 ggacgtggca taatatttcg ccaaccatg
//
LOCUS       DBEJNA010000032        24738 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEJNA010000032 DBEJNA010000000
VERSION     DBEJNA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.32"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..117)
                     /locus_tag="ACL3JB_001533"
                     /pseudo
     CDS             complement(1..117)
                     /locus_tag="ACL3JB_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            510..830
                     /locus_tag="ACL3JB_001534"
                     /pseudo
     CDS             510..830
                     /locus_tag="ACL3JB_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            951..1895
                     /gene="manA"
                     /locus_tag="ACL3JB_001535"
     CDS             951..1895
                     /gene="manA"
                     /locus_tag="ACL3JB_001535"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0686240.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1886..3281)
                     /locus_tag="ACL3JB_001536"
                     /pseudo
     CDS             complement(1886..3281)
                     /locus_tag="ACL3JB_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3487..4232
                     /locus_tag="ACL3JB_001537"
                     /pseudo
     CDS             3487..4232
                     /locus_tag="ACL3JB_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(4261..4716)
                     /locus_tag="ACL3JB_001538"
     CDS             complement(4261..4716)
                     /locus_tag="ACL3JB_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0686241.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4736..5911)
                     /locus_tag="ACL3JB_001539"
     CDS             complement(4736..5911)
                     /locus_tag="ACL3JB_001539"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0686242.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELDGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5970..6815)
                     /locus_tag="ACL3JB_001540"
     CDS             complement(5970..6815)
                     /locus_tag="ACL3JB_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0686243.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6940..7497
                     /locus_tag="ACL3JB_001541"
     CDS             6940..7497
                     /locus_tag="ACL3JB_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0686244.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7516..7983
                     /locus_tag="ACL3JB_001542"
     CDS             7516..7983
                     /locus_tag="ACL3JB_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0686245.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            8072..8701
                     /gene="upp"
                     /locus_tag="ACL3JB_001543"
     CDS             8072..8701
                     /gene="upp"
                     /locus_tag="ACL3JB_001543"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0686246.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8875..9465
                     /gene="clpP"
                     /locus_tag="ACL3JB_001544"
     CDS             8875..9465
                     /gene="clpP"
                     /locus_tag="ACL3JB_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0686247.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9544..9792
                     /locus_tag="ACL3JB_001545"
     CDS             9544..9792
                     /locus_tag="ACL3JB_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0686248.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9893..11053
                     /locus_tag="ACL3JB_001546"
     CDS             9893..11053
                     /locus_tag="ACL3JB_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0686249.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11321..12190
                     /locus_tag="ACL3JB_001547"
     CDS             11321..12190
                     /locus_tag="ACL3JB_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0686250.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            12194..13150
                     /locus_tag="ACL3JB_001548"
     CDS             12194..13150
                     /locus_tag="ACL3JB_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0686251.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSTSPTYGAFFGAMLVGALLSG
                     VVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            13150..13914
                     /locus_tag="ACL3JB_001549"
     CDS             13150..13914
                     /locus_tag="ACL3JB_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686252.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13914..14624
                     /locus_tag="ACL3JB_001550"
     CDS             13914..14624
                     /locus_tag="ACL3JB_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686253.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14932..15588
                     /locus_tag="ACL3JB_001551"
     CDS             14932..15588
                     /locus_tag="ACL3JB_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0686254.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15696..16791
                     /gene="prfB"
                     /locus_tag="ACL3JB_001552"
     CDS             join(15696..15767,15769..16791)
                     /gene="prfB"
                     /locus_tag="ACL3JB_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0686255.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTELD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16809..17501
                     /gene="ftsE"
                     /locus_tag="ACL3JB_001553"
     CDS             16809..17501
                     /gene="ftsE"
                     /locus_tag="ACL3JB_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0686256.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDLDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17494..18420
                     /gene="ftsX"
                     /locus_tag="ACL3JB_001554"
     CDS             17494..18420
                     /gene="ftsX"
                     /locus_tag="ACL3JB_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0686257.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTEKLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18706..20886
                     /locus_tag="ACL3JB_001555"
     CDS             18706..20886
                     /locus_tag="ACL3JB_001555"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0686258.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPIFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVLG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20938..21753
                     /locus_tag="ACL3JB_001556"
     CDS             20938..21753
                     /locus_tag="ACL3JB_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0686259.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21893..23236
                     /locus_tag="ACL3JB_001557"
     CDS             21893..23236
                     /locus_tag="ACL3JB_001557"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0686260.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23451..24641
                     /gene="metK"
                     /locus_tag="ACL3JB_001558"
     CDS             23451..24641
                     /gene="metK"
                     /locus_tag="ACL3JB_001558"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0686261.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
BASE COUNT         7537 a         4619 c         5402 g         7180 t
ORIGIN      
        1 gacaatggtt tgagcgtctg ctttcttagg atgttctgga cgtggcgtaa tatttcgcca
       61 accatggcgc ttcaacagtt gatagaaggc atcacgtgtg taggaatgac ctaactcctt
      121 ctatagtgta ttgaatctat aacagtacac cttggctgct aaaatatttc tataaattaa
      181 tttgactttt ctgatagagt tgttcacatc ttatttcaaa ctactataaa agttctataa
      241 tctctttata agatttgccc atcagacgaa atataatgga ttgaaactag aatagtacac
      301 ctctacttct aaaacattgt tagaaatcga tttgactgtc ctgattgatt tgtcctgttc
      361 ttgtttcatt ttactataga acgatttgaa ggcgtttatg atatttagct gtacgagagt
      421 cttttaaaag tgttttgatg gtttggattt cttctttagt tgatttcata tcactattat
      481 ataatgcttt ttgattttag tttagtatta tcgtagaaaa tggactcggt gctatggata
      541 caccggatga gaatggttat gtagcagata actatcggat tacttactta gaggcccaca
      601 tcaaggccat gcgagatgcc atttaccaag acggggttga cttgcttggt tatacgactt
      661 ggggctgtat cgatctggtt tcagctggca caggggaaat gaataagcgc tatggcttta
      721 tctatgtaga tcgagataat gtaggaaacg gagctctcaa acgtagcaag aagaagtcct
      781 tctattggta caaggatgtc attgatagca atggtgcaag catcgggtag agcacatttg
      841 tttactattt ttataaaatc ttctccctgc tttataagat gtaaaaaaga gttcaattcg
      901 aactcttttt ttgctataat gaggggagaa aaatcagaca ggagatcgac atgtcagaac
      961 cattattttt acaatcagtt atgcaagaaa aaatctgggg tggagccaag ctacgtgatg
     1021 agtttggcta cgacatccca agtgaaaaaa tcggagaata ttgggccatc tcagcccatc
     1081 caaatggagt ctctaaagtt gccaatggtc gttacgaggg aacagatctt gctactttgt
     1141 atgcggaaca ccgtgaatta tttggcaatc gtccagaacc tgtatttcca cttttgacca
     1201 agatcctcga tgccaacgac tggctcagtg tccaagttca cccagacgat gcttatggac
     1261 tcgagcatga aggcgaactc ggaaaaacag aatgctggta cattatcgca gcggatgaag
     1321 gttcagagat tatctacggt cacaatgcca agtcaaaaga agaactccgc cagcaaatcg
     1381 aggataagaa ctgggatgcg ctgttgacaa aagtgccagt taaagcagga gatttcttct
     1441 atgtaccaag cggtaccatg cacgctatcg gggcgggtat cttgattctt gaaacccagc
     1501 agtctagcga taccacttac cgtgtctatg actttgaccg taaggatgac aagggcaatt
     1561 tacgtgaact tcaccttgaa aaatctatcg atgtcttgaa cattggtgaa cccgcaaata
     1621 gccgtccagt gacaatcaaa gcagatgatc tacgttccac tctccttgta tccaatgatt
     1681 tcttcgcagt ttacaaatgg gaaattactg gaaaagttaa ctttgaaaag acagctgact
     1741 acagcttgtt gagtgtcttg gctggtcaag gtcaactaac tgttgacggg aaaaactatc
     1801 caatccaaaa agggagacac tttatcctac caagtgatgt tgaagcttgg actctggaag
     1861 ggcaagattt agaattaatt gttagtcatc cataaaaaag aaagggcctg agttcattac
     1921 tcaagtcctt ttgattacat aaattgggcg atgaagacca cgatgatgat tggaatgacg
     1981 gaacgaagaa acgaagaagg aagagccaga cttggaacag tccttgtttc catgctcttt
     2041 catcgagatg gagttcctcc attgcaagag cctttttaaa gatatagcct gtaaaaagtg
     2101 aaaggtagag agctccaaat ggcatgagga gattggaaac caagaagtcc atagcgtcaa
     2161 agaaggtctt accaaaaatg tgaacatccg ccatgacacc gtaagatagg gctgaaggaa
     2221 tgccaaagac aaaggtcaaa attcctaaaa taacactcca tttggcacgt ttgctgttat
     2281 cctggttggt gatattgccc acattgatct ccagcatcac gacagaagaa gtgacagtcg
     2341 caaagaggaa gaggacgtag aaaatggttc caaaaggcat cttgtcaaag agttgaggca
     2401 agacgataaa gagcaagctc ggtccccctt cagactggat attgaagggg gatcgagctt
     2461 ggaaaatggc tagacctgcc atgatggata tcgagatatt catggctacg atggagattc
     2521 ctgactggac tagattggtt ttcttgtcca agtaaggagc ataggtcaac atgactgtaa
     2581 cccctagtga gagggcaaag aaagattgtc ccagagcata gaggagacca gcgctagtca
     2641 gttttgaaaa gtctggtttg aggaagtaaa gaacccttcc atggcatttg gcaaactgag
     2701 agagcgaccg atgataacaa caaagatgat aaagagcagg ggcatcatga ctttcgaagc
     2761 tctttcaatc cctttttgaa caccacgtga tacaataaag atatttaata agataaaggc
     2821 tgcttgagct actagggcaa tggctggatt tgaaatgatt gaagtaaata actgagcata
     2881 atcacccgtt ccaccaagtt ggaacaattt cccaaactca atacctagat agactagaat
     2941 ccatcctccg ataacactgt aaaaagataa gaggataaag agggcaaagg cgccaatcca
     3001 accgataaag ttgtacttgt tattcttgcc cagttttcca aaggttttga tagcggaaac
     3061 gccagccact acggccaagg gcaaactcag ccagcaggag agggaaaccg attaaaatag
     3121 tggaaatgaa aaagattagt aaaaagcctc caccgccatt agcagcagtc atgtagggaa
     3181 acttccaaac ggaaccaagc ccgatgaccg agcccgatga ccgagccagc agatgctaga
     3241 ataaagccaa gtttcgaccc ccattgtgat ttttctgaca tagttaaact ctgatctcct
     3301 ttttcaaaat aagaaaaagc tacttgagtt gtcaaatagc cttctgtttg attgatagac
     3361 ttgactatcc tattatgttt tctaaggtct gtcaagaaaa ccattttcaa gttttcacac
     3421 ctttctcaaa aacgcttgac tctgacctaa ggggaggggt tatactatca ttgtaaggag
     3481 gaaatcatgt accatataaa agaagctgcg cagctttcag gtgtctctgt caagaccctg
     3541 ccctgcatca ctatgacaag ataggactct tggtcccctt aaagtcggaa aacggctatc
     3601 gaacctatag tcaagaggat ttggaacgcc ttcaggtcat tctttactac aaatatctag
     3661 gcttttcttt agagaaaata gcagaactgt taaaggaaga aaggacagat ttattgcccc
     3721 atttgactag gcagttggac tatctaactc gcgaaaggca acatctggat accttgattt
     3781 ccaccttgca aaaaactatt caagaacaaa aaggagaaag aaaaatgacc attgaggaaa
     3841 aattcacggg atttagctat caagacaatc aaaaatacca ccaagaagcg gtagagaaat
     3901 atggtcaaga agtcatggga caagcgctcg aacgccaaaa aggtcacgaa gacgaggcta
     3961 cggccgcctt taaccaagtc tttcaaactt tggcacaaaa tcttcaagtt ggtttacctg
     4021 caacagcaac cgaaaaccag gagcaagcag ccaagctctt gcaagccatt cgcacttatg
     4081 gatttgactg ctctattgag gtattcggtc atatcggtaa aggttacgtc tacaacccag
     4141 agtttaagga aaacattgac aagtttggtt ctgaaacagc ccagtacacg tcagatgcca
     4201 ttgcggctta cgttcagaca aatgcagaat aaataggcta ggaatttcct agcctatttt
     4261 ttacttcaaa tcataaagcc agtcgtcacc gtttttgtag taaaagaatt cactgagatc
     4321 ttcttctaga aacacacgaa gcatatcaga catatcatcg gttgcaagtt ttagatgaga
     4381 aagattttca aagtcctccc accaaacttt cccttcgtct gaagactgga gttcaccagt
     4441 aaagtgttct gtcttgtaaa aaaggacgac ataacgataa tccttgtcgt cataccagtt
     4501 tttgatacca cagagttggg gtttggaaat gatcagacca gtttcttctt tcacttcacg
     4561 aatgacagca tcgacaaagg attcgccacg ttcaacatga ccaccaggaa aagtaatgcc
     4621 agaccagtcg ggactaactc ggtcttggac caggacctta tctccgtttt taatcataca
     4681 catgttaaca aattcgactg cctctcttct gttcattctt cacaaccttt aatctttaat
     4741 cataatgcag acttcccgcc acccagccgg tacagagggc agaagtgatg ttaaagccac
     4801 ccgtgtgggc attgatatcc ataacttcgc ctgcaaagtg gaggccaggt accagcttac
     4861 tttcaagggt tttaggattg atttccttga gactgactcc acccttggta acaaaggact
     4921 ttgcaaggga catttttcca gttacaggaa ttttaagttc tttaatggac tggacaagtt
     4981 gttctcgttc cttttcagtc agttgtttga ctttttcagg atatccttgt acaaaaaatt
     5041 cggccaagcg ttctggtaac aaggttttta aagcgttttt caaggatttt tcccgatttt
     5101 cttctagaaa tgtaaccaag tccttctcag aaagttgagg caaaacatcg agtgagagaa
     5161 cctccccacc tttgacaaag ctagacatgc gtagggcagc aggacctgac aaaccaaagt
     5221 gggtaaagag taaatcatga gtgatgacat gcttaccata acttagggtc acatcgtcca
     5281 gagaaatccc ttgtaaggct ttatgtggaa aatctgttaa taaaggactt tcagcagcct
     5341 caagatcggt gatggtatgc ttaaaatggc gagcaatctc gtgaccaaaa ccagtcgaac
     5401 cagtcgaagg ataagactta ccacctgttg tgacaatgag tttctcacaa gtgaaggttt
     5461 gatccgctga cttaaggaca aactggtcat ctactttttt aacagaaacg atttctattt
     5521 gagtagcaac ttgaccatct agttcggtga ttttcttttc caaagcttcg ataatagtcc
     5581 gagacttgtc actggctgga aagacgcgtc cgtggtcttc gaccttaagt ttaacaccat
     5641 tttctgtaaa aaagttgatg atgtcatgat tatcgaactg ggagaaaaca ctgtaaagaa
     5701 agcgtccgtt tccaggaatt ccagctagca ggttgtctaa gctaccattg ttggtcacat
     5761 tgcaacgtcc cccaccagtc ccagctaatt tttttccaag tttccgattt ttttcgatga
     5821 ggagggtttt ctgtccataa aagctactgg aaatcgtagc catcatacca gcaggtcccc
     5881 caccgatgac aatagtatca aaatgtttca tagctctatt gtaccacaaa aaaacaagag
     5941 atgatggtca cctcttgtca agaatgcaat taatcaattt catagcccat cagcaaaccg
     6001 ccctcttctg catagaaact gcagagacca gaggttggta gaattttaat atccgcttgt
     6061 gggaaggttt cacggattcg ctctgagagc tgttgacaac atttttcgtt attgcgttgg
     6121 gccatgacaa tacggccacc agcatatcca gcttttacta actcatcata ggcagcttga
     6181 actgatttct ttgatcccct tgctttttgt agcaattcga gagtcccagt ttcactagct
     6241 tttccgacca tacgaatgtt gagaaggcca acgaccgtac cgataagctt gctcaaacgg
     6301 ccgttcttca ccaagttatc gactttggct aggacaaaga gcaacttagt tttttcttga
     6361 taggcggtga tagcttcaac cacttcttca aaagacaagc cctggtcaat caagtcattc
     6421 aatttttcta cgagtaggtc aacttcacca ccagcagata aactatcaat cacatgaatc
     6481 ttagtgtcag gatggtcttc cagataaata ttctttgcta gttgagcact attgtgactg
     6541 ccagaaaggg tacctgtgat ggttactagg aaaatgtttt tggcaccttc aaatgctcgc
     6601 aaatagtcat ctgggcttgg acaagctgat tttgaagctt ctgcagttgc atacatggtt
     6661 tccatcattt ggtcaatatc gagactggcg tcatcaacaa agacctgatc agctacttga
     6721 atggttaagg ggacacttac aaaggttgtg ttaatagctg gtgttggcag ttgacgataa
     6781 tcacaaccag agtcagcaat aatcttccaa gtcatagaaa ttctccatct ttgtcagtta
     6841 tacattgaca aaggttctgt ctttttttac aattatatca tgaaaactct tgaaacaaaa
     6901 gcatcatccg tctgttgtga caagtagaaa gaaaatgtta tgtctgaacg tagaatctct
     6961 gaaaagtctc ttgaaaatct cagaaaatca aaccaagaat ccaatttatt aaccagagaa
     7021 gccattgaaa cagccctctt gcaactcttg gaaaaaaagg agctgaccaa gattagtatt
     7081 tctgaattgg tcaaacgtgc aggtgtttcg cgtgcggcct tttatcgcaa ttatgactcc
     7141 aaagaggaaa ttttagagag cgtctttaaa cgaactgtcc acaatattat ggaacagctg
     7201 catcattacg atttaaagac agacctttat ttggtttggg ttcacctttt ccgggaggcc
     7261 agaaaggaag ctagagtaat tcaattggcc ttggattacc atctggaaaa aatctttgtc
     7321 caagccatgc aggaatttct agaaaaatac catgggaaat caaaaggtgt cagctcttat
     7381 cttcattcct tctggagctc agccatcgtc tctgtccttc taaaatggat caaggatggc
     7441 atgaaggtac cagctgaaaa gattgcagat ttaggtttac cattttttaa aaaatagaga
     7501 aaaaggagaa aagagatgac tgaaaaaaga ctggcctggg atgagtattt tgcagcccaa
     7561 gctctactaa ttgcgaatcg ttccacttgt aaacgtgcta aagtgggcgc gattctggta
     7621 aaagataata aggttatttc cactggttac aatggttcgg tgtcagggac tgagcattgt
     7681 attgatcacg aatgtttggt cattgaaggc cactgtgttc gcacccttca cgctgaggtc
     7741 aatgctatcc ttcaaggtgc tgagcgtggt gttcccaaag gctttacagc ctatgtaacc
     7801 cattttcctt gtctcaactg tacaaaacaa ttgcttcagg tcggctgcaa gcgcgtggtt
     7861 tatatcaacc agtaccgaat ggacgactac gcccaatacc tttatcaaga aaaagggaca
     7921 gaattgaccc atttaccact tgagacagta cagacagctc ttaaagaggc tgatctaatg
     7981 taaaaattat caaaaataaa tggtttagaa agatttttaa accgtttttt ggtataataa
     8041 gaagaataaa ttgaaagaag gaattccaaa aatgggaaaa attgaagtta ttaatcaccc
     8101 actgattcaa cacaaattgt caatcttgcg tcgtacagat acttctacaa aagcttttcg
     8161 tgagctagta gatgagattg caatgttgat ggggtatgaa gtacttcgtg atcttccact
     8221 agaagatgtg gaaatcgaaa caccaattac aaaaacagtt caaaaacaat tggcaggtaa
     8281 gaaattggcc atcgtcccaa tcttgcgtgc aggtatcggg atggttgatg gtctcttgag
     8341 cttggttcca gctgctaaag ttggccacat cggtatgtac cgtgatgaag aaacacttca
     8401 accagttgaa tacttggtga aattgcctga ggacattgac caacgtcaaa tttttgtagt
     8461 agacccaatg ttggcaacag gtggctcagc aatcttggct gttgattctc ttaaaaaacg
     8521 tggcgcatca aatatcaaat ttgtctgcct tgtatctgct ccagagggtg taaaagccct
     8581 tcaagaagct catccagatg tagaaatctt tacagcagcc ttggatgaac gtttgaacga
     8641 acacggttat atagttccag gtcttggaga tgctggagac cgcttgttcg gtacaaaata
     8701 agatcgaaaa gaagaatgac ttggaaaagt atttctagtc acgaaaggag gttgggtttt
     8761 tgtttctgtc taatgaaagc agagcaaaaa tttgaccttt tttgaccaag atattataat
     8821 agtcttatct tcagtcattt gaccaacaaa attaaaactc aaaaggagaa atgaatgatt
     8881 cctgtagtta ttgaacaaac aagccgtgga gaacgttctt acgatattta ctcacgtctt
     8941 ctcaaagacc gcatcattat gctgacaggt ccggttgaag acaatatggc taactctgtt
     9001 attgcccaat tgcttttctt ggatgcccaa gatagtacga aagatattta cctttatgtc
     9061 aatacaccag gtggttctgt ttcagctggt ttggcaatcg tagataccat gaactttatc
     9121 aaggcagatg tccaaaccat tgttatggga atggctgcat ctatggggac tgtcatcgca
     9181 tcaagtggag caaaaggcaa acgtttcatg cttccaaatg ctgaatacat gattcaccaa
     9241 ccaatgggcg gtacaggtgg tggtacccaa caaactgata tggctatcgc tgcagaacac
     9301 ttgctcaaaa ctcgtaatac cttggaaaaa atcttggctg aaaattcagg tcagtcaatg
     9361 gaaaaagtcc atgcagatgc agaacgtgat aactggatga gcgcccagga aacacttgaa
     9421 tatggcttta ttgatgaaat tatggccaac aattcattga actaatgatg atagaaggca
     9481 aactcgactg ggtttgcttt ttttggtata atagggagag atttcttaga aagaggattt
     9541 atcatgtttg aaaaagtcaa tcgctctggc ttgattatct atctttacta taatcgtgat
     9601 gccaaaaaac tgcaggatta tggagatatt acctatcatt ccaagaaaca tcgttactta
     9661 caactctatg ttccaactca agaagtggag caattggtcg gacgcttgag caaggaaaaa
     9721 tttattaaaa aagttagggt ttgtcatatc caagagttgg aaacaccctt tgtgggcaat
     9781 ctttatcgat aggaaaacgt tatcatcgaa aaagttcaag gaaaacattg acaattttct
     9841 gataattcgg tatattctta acagactatt taagaaataa ggagacaaaa agatgaagaa
     9901 aaaatttgcc ctatcgtttg tggcgcttgc aagtgtagca cttcttgcag cctgtggaga
     9961 agtgaagtct ggagcagtca acactgctgg taactcagta gaggaaaaga caattaaaat
    10021 cgggtttaac tttgaagaat caggttcttt agctgcatac ggaacagctg aacaaaaagg
    10081 tgcccaattg gctgttgatg aaatcaatgc cgcaggtggt atcgatggaa aacaaatcga
    10141 agtagtcgat aaagataata agtctgaaac agctgaggct gcttcagtta caactaacct
    10201 tgtaacccaa tctaaagtat cagcagtcgt aggacctgcg acatctggtg cgactgcagc
    10261 tgcggtagcg aacgctacaa aagcaggtgt tccattgatc tcaccaagtg cgactcaaga
    10321 tggattgact aaaggtcaag attacctctt tattggaact ttccaagata gcttccaagg
    10381 aaaaattatc tcaaactatg tttctgaaaa attaaatgct aagaaagttg ttctttacac
    10441 tgacaatgcc agtgactatg ctaaagggat tgccaaatct ttccgcgagt catacaaggg
    10501 tgaaatcgtt gcagatgaaa ctttcgtagc aggtgacaca gactttcaag cagcccttac
    10561 aaaaatgaaa gggaaagact ttgatgctat cgttgttcct ggttactata atgaggctgg
    10621 taagattgta aaccaagcgc gtggcatggg aattgacaaa ccaatcgttg gtggtgatgg
    10681 attcaacggt gaggagtttg tacaacaagc aactgctgaa aaagcatcaa acatctactt
    10741 tatctcaggc ttctcaacta ctgtagaagt ttcagctaaa gctaaagcct tccttgacgc
    10801 ttaccgtgct aagtacaatg aagagccttc aacatttgca gccttggctt atgattcagt
    10861 tcaccttgta gcaaacgcag caaaaggtgc taaaaattca ggtgaaatca aggataacct
    10921 tgctaaaaca aaagattttg aaggtgtaac tggtcaaaca agcttcgatg cagaccacaa
    10981 cacagtcaaa actgcttaca tgatgaccat gaacaatggt aaagttgaag cagcagaagt
    11041 tgtaaaacca taatagaaaa atgttgaaat agggaatgag cctttgactc actccctgtt
    11101 tcgatattta atactcttcg aaaatctctt caaactgcgt caacgtcgcc ttggattata
    11161 tatgtgactg acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgt
    11221 ggctagtttc ctagtttgct ctttgatttt cattgagtat aagaacctat caaaaagtga
    11281 gggaaacccc tcggaattat aaatagaaag agtgaatctt atgctacaac aactcgtaaa
    11341 tggtttgatt ctaggtagtg tttacgcgct gttagcccta ggatatacca tggtttacgg
    11401 aattatcaag ctcatcaact tcgcccatgg tgatatttat atgatgggag cctttatcgg
    11461 ttatttcttg atcaattctt tccaaatgaa tttctttgta gcgcttattg tagctatgct
    11521 agcgacagct attcttggtg tcgtgattga gtttcttgct taccgacctt tgcgccactc
    11581 tactcgtatt gctgttttga ttacggctat tggggtttct ttcctattgg agtatggaat
    11641 ggtctatctg gttggtgcca atacccgtgc cttccctcaa gcgattcaaa cagttcgata
    11701 tgatttggga ccaattagct taacaaatgt gcagttaatg attttggcca tttccttgat
    11761 tttgatgatt ttgttacaag tcattgtcca aaagactaag atggggaaag ccatgcgtgc
    11821 agtatcagta gatagcgacg cggcgcaatt gatggggatc aatgtaaacc gtacgattag
    11881 ctttaccttc gctttgggtt ctgctcttgc gggtgcggct ggtgttctga ttgctcttta
    11941 ttataactct cttgagcctt tgatgggggt tactccaggt cttaaatctt tcgttgccgc
    12001 agtacttggt ggtatcggaa ttattcctgg tgcggctctt ggtggctttg tgattggtct
    12061 attggaaacc tttgcgactg cctttgggat gtcagatttc cgtgatgcca ttgtttatgg
    12121 aatcttgttg ttgatcttga ttgtccgccc agctggtatc cttggtaaga atgtgaaaga
    12181 gaaggtgtaa acgatgaagg aaaatttaaa agttaatatt ctatggttac tccttttgtt
    12241 agctggctat agcttgatta gtgtactggt ttcagtcgga gtacttaatc tattctatgt
    12301 acagatttta caacaaattg gaattaatat tattttggct gttggtctca acttaatcgt
    12361 tggtttttca ggacaatttt cacttggtca tgctggtttc atggcgattg gtgcctatgc
    12421 agcagctatt attggttcta catcaccaac ctacggtgcc ttctttggag ctatgcttgt
    12481 aggggctttg ctttcaggag tagttgcctt acttgtcggc attccaacct tgcgcttgaa
    12541 gggggactat cttgcggtag caactctggg tgtttctgaa attatccgta tctttatcat
    12601 caatggtgga agtcttacaa atggtgcggc aggtatctta gggattccta actttacaac
    12661 ttggcaaatg gtttacttct ttgtcgtgat tacaaccatt gcaaccttga acttcttgcg
    12721 tagcccaatt ggccgttcaa ccctctctgt tcgtgaagat gaaatcgctg ctgagtcagt
    12781 tggggttaat acgactaaaa ttaaaatcat cgcttttgtc tttggtgcca ttactgcaag
    12841 tattgctggg tcacttcagg caggatttat cgggtctgtt gtaccgaaag attacacctt
    12901 catcaactca atcaacgttt tgattattgt tgtatttggt ggactcggtt ccattacagg
    12961 tgcgattgtt tcggctattg ttctgggaat tttgaatatg cttctccaag atgttgctag
    13021 tgtgcgtatg attatttacg ctttggcctt ggtattggta atgattttca gaccaggtgg
    13081 actccttgga acgtgggaac tgagcctatc acgtttcttt aaaaaatcta agaaggagga
    13141 acaaaactaa tggcattact tgaagtaaaa cagttaacca aacattttgg tggtctaaca
    13201 gctgttggag atgtgactct tgaattgaac gaaggggaac tggttggatt aatcggtcca
    13261 aacggagctg ggaaaaccac ccttttcaac cttttgaccg gtgtttatga accaagcgag
    13321 ggaacagtaa ccctagatgg tcaccttttg aatgggaaat caccttataa gattgcctct
    13381 ttgggacttg gacgtacttt ccaaaatatc cgtcttttta aagatttaac agttttagac
    13441 aatgttttga ttgcttttgg aaaccatcac aaacagcatg tttttactag tttcttacgc
    13501 ttaccagctt tttacaagag tgaaaaagaa ttaaaggcta aagctttgga attgttgaaa
    13561 atctttgatt tagatggtga tgcagagact cttgctaaaa atctttccta cggacaacaa
    13621 cgtcgtttgg aaattgttcg tgcccttgct acggaaccta aaattctctt cttagatgaa
    13681 ccagcagcag gtatgaaccc acaggaaaca gccgaattga ctgagttaat tcgtcgtatc
    13741 aaagatgaat ttaagattac aatcatgttg attgaacacg atatgaatct ggtcatggaa
    13801 gtaacagaac gtatctacgt acttgaatat ggccgtttaa ttgctcaagg aactccagac
    13861 gaaattaaga ccaataaacg cgttatcgaa gcttatctag gaggtgaagc ctaatgtcta
    13921 tgttaaaagt tgaaaatctt tctgtgcatt acggtatgat ccaagcagtc cgtgatgtaa
    13981 gctttgaagt taatgaagga gaagttgttt cccttatcgg tgccaacggt gcaggtaaga
    14041 caactattct tcgcaccttg tcaggtttgg ttcgaccaag ttcaggaaag attgaatttt
    14101 taggtcaaga aatccaaaaa ataccagctc agaaaatcgt ggcaggtggt ctttcacaag
    14161 ttccagaagg acgccacgtc tttcctggct tgactgttat ggaaaatctt gaaatgggag
    14221 ctttcttaaa gaaaaatcgt gaagaaaatc aagctaactt gaagaaggtt ttctcacgct
    14281 ttcctcgtct tgaagaacgg aagaaccaag atgcagctac tctttcagga ggggaacaac
    14341 aaatgcttgc catgggacgc gctcttatgt caacaccaaa acttcttctt ttagatgaac
    14401 catcaatggg acttgcccca atcttcatcc aagagatttt tgatatcatt caagatattc
    14461 agaagcaagg aacaaccgtc ctcttgattg aacaaaatgc caataaagca cttgcaatct
    14521 ctgaccgagg atatgtactg gaaacaggga aaatcgtcct atcaggaaca ggaaaagaac
    14581 tcgcttcatc agaagaagtc agaaaagcat atctaggtgg ctaaaacaat ccagtggatt
    14641 gttttagtcg gcagatggag attacgaagt aatcatcaat atagtccggg ggaccttttt
    14701 agtcggtaga ttgagattgc aaacaaatct gcatctacat tgaaagctta atttctaata
    14761 attgaaaaaa tccaatgaaa agtttcttac cttcattcac agagctcgat tttagagctc
    14821 tttttgctag cttattcata cttttctaaa ttttgaaaaa gaaatgtaag cgtttgatag
    14881 atttgcaaaa agattgtata atagggataa gaatagaaaa ggagaagtct catggcagtt
    14941 aaagatttta tgacccgcaa ggtagtttat attagtccag atacaacagt atctcatgca
    15001 gcagatttga tgagagagca agaattgcac cgcttgcctg ttatcgaaaa tgatcaatta
    15061 gttggtttgg tgactgaggg aaccattgca caagcaagtc catctaaagc aacaagtctt
    15121 tctatctatg agatgaatta tcttctgaat aagacaaaag taaaagatgt catgattcgc
    15181 gatgttgtca ctgtctcagg ctatgctagt ctagaagatg caacttatct gatgttgaaa
    15241 aataagattg gtattctccc tgtcgtagat aaccatcaag tatacggagt tattactgac
    15301 cgtgacgttt tccaagcctt tcttgaaatt gcaggttatg gcgaagaagg gattcgtgta
    15361 cgctttgtta cagaagatga agttggtgtt cttggaaaaa ttatttcttt gattgtagaa
    15421 gaaaatttga atatatccca tacagtcaat attccgcgta aggatggtaa ggtcattatc
    15481 gaagtgcaaa tcgatggatc aattgattta ccagccttga aagaaaaatt tgaagcaaat
    15541 ggtattcaag tggaagaaat cgctcgcact tcagcaaaag tcttgtaaga agggaagccc
    15601 aaaggcttct tttttcatga aaaggggatt agagcaaaag atggaaagaa atgataaaat
    15661 atgctataat gaaataatgt aaaaaaggag tatttatgga catttcagta attcgtcaga
    15721 aaattgacgc aaatcgtgaa aaattagctt ctttcagggg gtctctttga cctcgaaggg
    15781 ctagaggaag agattgccat cttggaaaac aagatgacag aacttgattt ttggaacgat
    15841 aatattgcgg cccaaaaaac gtcgcaagaa ttgaatgaat taaaaaacac ttacaatacc
    15901 ttccataaga tggaagagtt gcaggatgaa gtcgaaattt tattggattt tttggctgaa
    15961 gacgagtcag tgcatgatga actggtagcg cagttagccg aacttgataa gataatgacc
    16021 agctacgaga tgactctact cttgtcagaa ccttatgacc acaacaatgc catcttggaa
    16081 atccatccag gttctggtgg tactgaggcg caggactggg gtgatatgtt gcttcgtatg
    16141 tatactcgtt atggtaatgc taaaggcttt aaagtggaag tgttggatta ccaagcaggt
    16201 gatgaggctg gtattaagtc ggtaacttta tcatttgaag ggcctaatgc ctatggtctc
    16261 ctcaagtcag aaatgggtgt tcaccgctta gtgcgaatct caccatttga ctctgccaaa
    16321 cgtcgccata cctctttcac atctgtagaa gtgatgccag aattggatga tactattgaa
    16381 gtggaaatcc gtgaagatga tatcaagatg gataccttcc gttcaggtgg tgccggtgga
    16441 caaaacgtca ataaggtttc aacaggtgta cgtttaactc acattccaac tggaattgtt
    16501 gtccaatcaa cagtggatcg tacccagtat ggaaatagag atcgtgccat gaagatgttg
    16561 caggctaagc tctatcaaat ggagcaagag aagaaggctg cggaggtaga ttctctcaaa
    16621 ggtgagaaaa aggagatcac ttggggaagc caaatccgtt cttatgtctt cacgccttat
    16681 actatggtaa aagatcaccg aactagcttt gaggttgctc aggtagataa ggttatggat
    16741 ggggatctag atggttttat cgatgcttat ctcaagtggc gaattagcta agatagaaag
    16801 gaactcacat gtcaattatt gaaatgagag atgtcgttaa aaaatacgac aacggaacaa
    16861 ctgctctacg cggtgtttcg gtcagcgttc aaccggggga atttgcttac atcgtaggac
    16921 cttcaggagc agggaagtca acttttattc gttctctgta tcgtgaagta aaaatcgata
    16981 aaggaagcct atcagttgct ggttttaatc tggttaagat caaaaagaaa gatgtcccgc
    17041 ttctacgtcg tagtgttggg gttgtcttcc aggattataa attgttacca aagaaaactg
    17101 tctatgaaaa tattgcttac gctatggaag taatcgggga aaatcgccgt aatatcaaaa
    17161 gacgagtgat ggaagttttg gacttggttg gattgaagca taaggttcgt tctttcccaa
    17221 atgaactctc aggtggggag caacagcgga ttgcgattgc gcgtgcaatt gtaaataatc
    17281 ccaaagtatt gatagctgat gagccaacag gaaatctgga tctggataat tcatgggaaa
    17341 ttatgaatct cttggaacgg attaacctac aaggaacaac tattttgatg gcgactcata
    17401 atagccagat tgtaaatacc ttgcgccacc gtgtcattgc cattgaaaat ggccgtgtcg
    17461 ttcgtgacga atcaaaagga gagtatggat acgatgatta gtagattttt tcgccattta
    17521 tttgaagcct taaaaagttt gaaacgaaat ggttggatga cagtagctgc tgtcagttca
    17581 gtcatgatta ctttgacctt ggtggcaata tttgcatctg ttattttcaa tacagcgaaa
    17641 ctagctacag atattgaaaa taatgtccgt gtagtagttt atatccgaaa ggatgtggaa
    17701 gataatagtc agacaattga aaaagaaggt caaactgtta caaataatga ctaccacaag
    17761 gtatatgatt ctttgaagaa catgtctacg gttaaaagtg ttaccttttc aagtaaagaa
    17821 gaacaatatg aaaaattaac cgagataatg ggagataact ggaaaatctt tgaaggagat
    17881 gccaatcctc tctatgatgc ctatattgta gaggcaaaca ctccaaatga tgtaaaaact
    17941 atagccgaag atgctaaaaa aattgaaggt gtctctgagg ttcaagatgg cggtgccaat
    18001 acagaaaaac tcttcaagtt agcttcattt atccgtgttt ggggactagg gattgctgct
    18061 ttgttaattt ttatcgcagt tttcttgatt tcaaatacca ttcgtattac cattatttcc
    18121 cgcagtcgcg aaattcaaat catgcgcttg gtcggagcta aaaacagtta tatccgtgga
    18181 ccgttcttgt tagaaggagc ctttatcggt ttattgggag ctatcgcacc atctgttttg
    18241 gtctttattg tttatcaaat tgtttaccaa tctgtcaaca aatcgttggt agggcaaaat
    18301 ctatccatga ttagtccaga tttatttagt ccgttgatga ttgccctact atttgtgatt
    18361 ggggttttca ttggttcatt gggatcagga atatccatgc gccgattctt gaagatttag
    18421 gtaaaatagc tgcttttatg aggagattgt aaaatctcct tttttgctac aagagttttt
    18481 gaaaagagat gcgcagaaga aaagagcttc caaagaagtc ccccagagaa gacttcttga
    18541 tggctaattt gaacttgaaa tttggcgcac tagaaatttt ttagaaaaaa gtgtaatttt
    18601 tttataaaag cctttacaaa aaaaattaaa gtggtataat taaatcatag aaagtgcaaa
    18661 cgttttcgta aaacgtttgc ctaaataaaa ataaaggaga tttgaatgat gaaagataca
    18721 ttcaaaaatg tcttgtcttt cgaattttgg caaaaattcg gtaaggcttt gatggtagtt
    18781 atcgcggtta tgccggctgc tggtttgatg atttcaatcg gtaagtctat cgtgatgatt
    18841 aacccaatct ttgcaccact tgtcatcaca ggtggaattc ttgagcaaat cggttggggg
    18901 gttatcggta accttcacat tttgtttgcc ctagccattg gaggaagctg ggctaaagaa
    18961 cgtgctggtg gtgctttcgc cgctggtctt gccttcatct tgattaaccg tatcactggt
    19021 acaatttttg gtgtatcagg cgatatgttg aaaaatccag atgctatggt aactactttc
    19081 tttggtggtt caatcaaagt tgctgattac tttatcagtg ttcttgaagc tccagccttg
    19141 aacatggggg tattcgtagg gattatctca ggttttgtag gggcaactgc ttacaacaaa
    19201 tactacaact tccgtaaact tcctgatgca ctttcattct tcaacgggaa acgtttcgta
    19261 ccatttgtag ttattcttcg ttcggcaatc gctgcaattc tacttgctgc tttctggcca
    19321 gtagttcaaa caggtatcaa taacttcggt atctggattg ccaactcaca agaaactgct
    19381 ccaattcttg caccattctt gtatggtact ttggaacgtt tgctcttgcc atttggtctt
    19441 caccacatgt tgactatccc aatgaactac acagctcttg gtggtactta tgacatttta
    19501 actggtgcag ctaaaggtac tcaagtatta ggtcaagacc cactatggct tgcatgggta
    19561 acagaccttg taaaccttaa aggtactgat gctagtcaat accaacactt gttagataca
    19621 gtacatccag ctcgtttcaa agttggacaa atgatcggtt cattcggtat cttgatgggt
    19681 gtgattgttg ctatctaccg taatgttgat gctgacaaga aacataaata caaaggtatg
    19741 atgattgcaa cagctcttgc aacattcttg acaggggtta ctgaaccaat cgaatacatg
    19801 ttcatgttca tcgcaacacc tatgtatctt gtttactcac ttgttcaagg tgctgccttc
    19861 gctatggctg acgtcgtaaa cctacgtatg cactcattcg gttcaatcga gttcttgact
    19921 cgtacaccta ttgcaatcag tgctggtatt ggtatggata tcgttaactt cgtttgggta
    19981 actgttctct ttgctgtaat catgtacttt atcgcaaact tcatgattca aaaattcaac
    20041 tacgcaactc cagggcgcaa cggaaactac gaaactgctg aaggttcaga agaaaccagc
    20101 agtgaagtga aagttgcagc aggctctcaa gctgtaaaca ttatcaacct tcttggtgga
    20161 cgtgtaaaca tcgttgatgt tgacgcatgt atgactcgtc ttcgtgtaac tgttaaagat
    20221 gcagataaag taggaaatgc agagcaatgg aaagcagaag gagctatggg tcttgtcatg
    20281 aaaggacaag gggttcaagc tatctacggt ccaaaagctg acattttgaa atctgatatc
    20341 caagatatcc ttgattcagg tgaaatcatt cctgaaactc ttccaagcca aatgactgaa
    20401 gcacaacaaa acactgttca cttcaaagat cttactgagg aagtttactc agtagcagac
    20461 ggtcaagttg ttgctttgga acaagtaaag gatccagtat ttgctcaaaa aatgatgggt
    20521 gatggatttg cagtagaacc tgcaaatgga aacattgtat ctccagtttc aggtactgta
    20581 tcaagcatct tcccaacaaa acatgctttt ggtattgtga cggaagcagg tcttgaagta
    20641 ttggttcaca ttggtttgga cacagtaagt cttgaaggta aaccatttac agttcatgtt
    20701 gctgaaggac aaaaagttac agcaggagat ctccttgtca cagctgactt ggatgctatc
    20761 cgtgcagcag gacgtgaaac ttcaacagta gttgtcttca caaatggtga tgcaattaaa
    20821 tcagttaaat tagaaaaaac aggttctctt gcagctaaaa cagcagttgc taaagtagaa
    20881 ttgtaatata cttgaggttg gaagctgtat tccaacctct tattttggga gaaaagaatg
    20941 aaatttttaa cactcaatac tcacagttgg atggagaaag aagcagagga aaaattccag
    21001 attttgcttg aagatattct tgaaaaggac tatgatttga tttgtttcca agaaatcaat
    21061 caggagatga cctcgtcaga ggtggaggtt aatgaccttt atcaagcttt gccagcagct
    21121 gagcctattc accaagacca ttatgttaga ctcttggttg aaaagttgtt agagcaaggg
    21181 aaaaattact actggacctg ggcttataac catatcggct atgaccgcta ccatgaaggt
    21241 gtggctatct tgtctaaaac acctattgaa gccagagaaa ttttggtttc agatgtggat
    21301 gatccaacag actatcatac tcgccgtgtt gccctagctg aaactgtagt cgatggcaag
    21361 gagctagcag ttgccagtgt tcatctctct tggtgggata aaggtttcca agaagaatgg
    21421 gcacgatttg aggctgtctt gaaaaaattg aacaagccac ttttactagc tggagatttt
    21481 aacaacccag caggtcagga aggttaccaa gctattttag ctagtccatt aggcttacaa
    21541 gacgcatttg aagttgctca agagaaaagt ggtagctata ctgttccgcc tgaaattgat
    21601 ggctggaaag ggaacactga accccttcga atcgattatg tctttactac caaagagtta
    21661 gcggtggaaa atttacatgt cgtatttgat ggtaacaaga gtccacaagt gagtgatcac
    21721 tatggcttga atgctatatt aaactggaaa taataactga aaagaggttg gaactataaa
    21781 attccagcct tttcttacta gagaagctac tggaaatagc ctaaataagt gagactactg
    21841 taatggaata aaatatggta taattgataa ggtagataga atcgaggatg ttatgtcatt
    21901 tacgaaattt caatttaaaa actatattag agaagccttg aaggagttaa aatttacaac
    21961 tccaacagag gtgcaagaca agttgattcc tattgttttg gcaggtcgtg acctagtagg
    22021 agaatcaaaa acaggttcag gtaagactca tactttcttg ttaccgattt tccagcaatt
    22081 agatgaagct agcgatagtg tacaagcagt gattactgca ccgagtcgtg agttggctac
    22141 tcaaatttac caagtagcgc gtcagatttc agctcactca gatgtcgaag ttcgtgtggt
    22201 taattatgtg ggtggtacgg ataaggctcg ccagattgag aaattggcaa gcaatcagcc
    22261 tcatattgtt attggaacac caggccgtat ctacgacttg gttaaatctg gtgatttagc
    22321 tattcataaa gccaagacat ttgttgttga tgaagcagat atgaccttgg atatgggatt
    22381 cttggaaact gttgataaga ttgctggcag tcttccaaaa gacttgcaat tcatggtctt
    22441 ctcagcgact atcccacaaa aactgcaacc attcttgaaa aaatacttat caaatcctgt
    22501 tatggagaaa attaagacca aaacggttat ttctgacacc attgataatt ggttgatttc
    22561 gaccaaggga catgataaga atgctcaaat ttaccagttg actcagttga tgcagccgta
    22621 tttggcaatg atttttgtta acactaaaac gcgtgctgat gaattgcatt catatctgac
    22681 tgctcaaggc ttgaaggttg caaaaatcca tggcgatatt gcccctcgtg aacgcaagcg
    22741 aatcatgaat caggtgcaaa atctggattt tgagtatatt gtcgcaacag atttggcagc
    22801 gcgtgggatt gacattgaag gtgtcagcca tgtcatcaat gatgccattc cgcaagactt
    22861 atcttttttt gttcatcgtg ttggtcgtac tggacgaaat ggcctaccag gtacagctat
    22921 taccctttat cagccaagtg atgactcgga tatccgtgag ttggagaaat tgggaatcaa
    22981 gtttagtcct aagatggtca aagacgggga atttcaagat acctatgacc gtgatcgtcg
    23041 tgccaaccgt gagaaaaaac aagataaact tgatatcgaa atgattggtt tggttaaaaa
    23101 gaaaaagaaa aaagtcaaac cgggttataa gaagaaaatt caatgggcgg ttgatgaaaa
    23161 gcgccgtaaa accaagcgtg ctgaaaatcg cgctcgcggt cgtgcagagc gtaaagctaa
    23221 acgccaaaca ttttaataga aattgttgga gtattgagct ccaacttttt gctttatgag
    23281 aacgaactat ctaaaccgaa acactacatt aaagactgca aattgcgatt aaaaatggta
    23341 taatgataaa gttatatagt cccgataaga tggtaggtat ttattacgaa gagttttcct
    23401 atcagtactt tgtaactcta taacaatatt ttttaagggg ggacattttt atgtcagagc
    23461 gtaaattatt cacgtctgaa tctgtatctg aggggcatcc ggataagatt gcagaccaaa
    23521 tttcagatgc gattttggat gctattttag caaaggatcc agaggcgcac gttgctgctg
    23581 aaacagctgt atatactggt tctgtccacg tttttggtga aatttctaca aatgcctatg
    23641 tggatattaa ccgtgtggtt cgtgatacca ttgcagagat tggttatacc aatacagaat
    23701 atggattttc tgctgagacg gtgggagtac acccatcttt ggtggaacaa tctcctgaca
    23761 tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa tgctgatcaa gatccactgg
    23821 acttgattgg agcaggtgac caagggctca tgtttggatt tgcagtagat gaaacagaag
    23881 agcttatgcc attgccaatt gcactcagtc ataaattggt tcgtcgtctg gcagaacttc
    23941 gtaagtctgg agaaattagc tatctccgtc cagatgcaaa atcacaagtt acagttgagt
    24001 acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt tatttctact cagcatgatc
    24061 cagaggccac taatgaacaa atccatcaag atgtgattga caaggtcatc aaagaagtta
    24121 ttccatcttc ttatcttgat gataagacaa aattctttat caatccgaca ggtcgttttg
    24181 taatcggtgg tcctcaaggg gactcaggtt tgactggtcg taagattatt gtagatactt
    24241 atggtggcta ctctcgtcat ggtggtggtg ccttctctgg taaagatgcg actaaggtgg
    24301 atcgttcagc ctcttatgcg gctcgctata ttgccaagaa tatcgttgca gcagaccttg
    24361 ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt tgcgcaacct gtttctgttc
    24421 gtatcgatac tttcggtaca ggaacagtag ctgaaagtca acttgaaaaa gcggctcgtc
    24481 aaatctttga ccttcgccct gcagggatta tccaaatgct ggacctcaag cgtccaattt
    24541 accgtcaaac atcggcttac ggtcacatgg gacgtacaga tattgatctt ccatgggaac
    24601 gtttggataa ggtagatgct ttgaaagaag cagtaaaata agattttaag aggggaacgt
    24661 cctctctttt ttatagtttt taactatact gggatactgt tctgaaaatc cattttgcga
    24721 aagtagagat ttacggct
//
LOCUS       DBEJNA010000033        23114 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEJNA010000033 DBEJNA010000000
VERSION     DBEJNA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.33"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(118..468)
                     /gene="rbfA"
                     /locus_tag="ACL3JB_001559"
     CDS             complement(118..468)
                     /gene="rbfA"
                     /locus_tag="ACL3JB_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0686262.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(719..3529)
                     /gene="infB"
                     /locus_tag="ACL3JB_001560"
     CDS             complement(719..3529)
                     /gene="infB"
                     /locus_tag="ACL3JB_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0686263.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQ
                     SLDGETIELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVD
                     HGKTTLLDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGA
                     SVTDITILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEH
                     GVMSTAWGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLD
                     KGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNE
                     APMAGDHFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNV
                     IIKADVQGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVR
                     PTPQARQQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVS
                     KVGTIGGFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMI
                     DGYNDIKMDDVIEAYVMEEIKR"
     gene            complement(3546..3845)
                     /locus_tag="ACL3JB_001561"
     CDS             complement(3546..3845)
                     /locus_tag="ACL3JB_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0686264.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(3838..4131)
                     /locus_tag="ACL3JB_001562"
     CDS             complement(3838..4131)
                     /locus_tag="ACL3JB_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0686265.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(4153..5289)
                     /gene="nusA"
                     /locus_tag="ACL3JB_001563"
     CDS             complement(4153..5289)
                     /gene="nusA"
                     /locus_tag="ACL3JB_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0686266.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(5333..5812)
                     /gene="rimP"
                     /locus_tag="ACL3JB_001564"
     CDS             complement(5333..5812)
                     /gene="rimP"
                     /locus_tag="ACL3JB_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0686267.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            complement(5938..6573)
                     /gene="trmB"
                     /locus_tag="ACL3JB_001565"
     CDS             complement(5938..6573)
                     /gene="trmB"
                     /locus_tag="ACL3JB_001565"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0686268.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(6570..7364)
                     /gene="ccrZ"
                     /locus_tag="ACL3JB_001566"
     CDS             complement(6570..7364)
                     /gene="ccrZ"
                     /locus_tag="ACL3JB_001566"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0686269.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(7525..8136)
                     /locus_tag="ACL3JB_001567"
     CDS             complement(7525..8136)
                     /locus_tag="ACL3JB_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0686270.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(8287..8520)
                     /gene="blpZ"
                     /locus_tag="ACL3JB_001568"
     CDS             complement(8287..8520)
                     /gene="blpZ"
                     /locus_tag="ACL3JB_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0686271.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(8562..9251)
                     /locus_tag="ACL3JB_001569"
     CDS             complement(8562..9251)
                     /locus_tag="ACL3JB_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0686272.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(9303..9686)
                     /locus_tag="ACL3JB_001570"
     CDS             complement(9303..9686)
                     /locus_tag="ACL3JB_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0686273.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(10315..10634)
                     /locus_tag="ACL3JB_001571"
                     /pseudo
     CDS             complement(10315..10634)
                     /locus_tag="ACL3JB_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(11154..11273)
                     /locus_tag="ACL3JB_001572"
     CDS             complement(11154..11273)
                     /locus_tag="ACL3JB_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0686274.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(11377..11526)
                     /gene="blpO"
                     /locus_tag="ACL3JB_001573"
     CDS             complement(11377..11526)
                     /gene="blpO"
                     /locus_tag="ACL3JB_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0686275.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(11770..12018)
                     /gene="blpK"
                     /locus_tag="ACL3JB_001574"
     CDS             complement(11770..12018)
                     /gene="blpK"
                     /locus_tag="ACL3JB_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGR0686276.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(12087..12356)
                     /gene="blpJ"
                     /locus_tag="ACL3JB_001575"
     CDS             complement(12087..12356)
                     /gene="blpJ"
                     /locus_tag="ACL3JB_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR0686277.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(12823..13020)
                     /gene="blpI"
                     /locus_tag="ACL3JB_001576"
     CDS             complement(12823..13020)
                     /gene="blpI"
                     /locus_tag="ACL3JB_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR0686278.1"
                     /translation="MNTKMMEQFEIMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            13301..13888
                     /locus_tag="ACL3JB_001577"
     CDS             13301..13888
                     /locus_tag="ACL3JB_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0686279.1"
                     /translation="MTSYKRTFVPQIDARDCSVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLAPKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLISHYYQYRWFLLSPRNLR"
     gene            13815..15458
                     /locus_tag="ACL3JB_001578"
     CDS             13815..15458
                     /locus_tag="ACL3JB_001578"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR0686280.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            15469..16830
                     /locus_tag="ACL3JB_001579"
     CDS             15469..16830
                     /locus_tag="ACL3JB_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0686281.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            16887..17015
                     /gene="blpC"
                     /locus_tag="ACL3JB_001580"
     CDS             16887..17015
                     /gene="blpC"
                     /locus_tag="ACL3JB_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0686282.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(17086..18426)
                     /locus_tag="ACL3JB_001581"
     CDS             complement(17086..18426)
                     /locus_tag="ACL3JB_001581"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0686283.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(18440..19177)
                     /locus_tag="ACL3JB_001582"
     CDS             complement(18440..19177)
                     /locus_tag="ACL3JB_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0686284.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALNYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(19191..19520)
                     /locus_tag="ACL3JB_001583"
     CDS             complement(19191..19520)
                     /locus_tag="ACL3JB_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0686285.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLK"
     gene            19797..20126
                     /locus_tag="ACL3JB_001584"
     CDS             19797..20126
                     /locus_tag="ACL3JB_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0686286.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(20294..21343)
                     /locus_tag="ACL3JB_001585"
     CDS             complement(20294..21343)
                     /locus_tag="ACL3JB_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686287.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(21340..22071)
                     /locus_tag="ACL3JB_001586"
     CDS             complement(21340..22071)
                     /locus_tag="ACL3JB_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686288.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTMQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            22139..22549
                     /locus_tag="ACL3JB_001587"
     CDS             22139..22549
                     /locus_tag="ACL3JB_001587"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0686289.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            22559..22846
                     /locus_tag="ACL3JB_001588"
     CDS             22559..22846
                     /locus_tag="ACL3JB_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686290.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
BASE COUNT         7261 a         5030 c         3942 g         6881 t
ORIGIN      
        1 caatgtttta gaagtagagg cgtactattc tagtttcaat atattttaaa agaatatttt
       61 tccatttcaa attcaaccta ttttcctcca ccaaaaaaga ggggcaaccc ctcttcttta
      121 gttcttatcc agattgcgta gcatctcgtc aatcttgttt ccatactcga tggactcgtc
      181 tttgacgaag gtcaaatctg ggattttgta caatttcaaa ttgcgaccaa gttcacgttt
      241 gatggtacca gttgcttttt caagcccgat ttgggctttt tggttatccg aagcaaggtt
      301 actcaaaatg gtgtaataaa ccttggcaac agacaagtca cccaacatct gaacatctgt
      361 gatggtcaca ccttggacac gtggatcacg aactttcttt tgcaaaatct cattgacttc
      421 acgcttgatt tccatgccca cacgatctgt acggaaatga tttgccatga tattcctttc
      481 tctactttga accaaaagct aggccagcag acctagctat tttaaacttc ttgattttca
      541 gtttaaattg aaacgaagtt caatttgaag tcatctgctt ctttcgccgt ggtgaaagtg
      601 atggaactga tttatcagtc ccatcacagg ggatttttga gaccctaggc tcaaaaataa
      661 gcaatgaaac catcggtttg cttgcgtccc tcaccaccta agaaaggagc aaaaaatctt
      721 atctcttgat ttcttccatg acatacgcct caatcacatc atccatctta atatcattgt
      781 agccgtcgat catcaatcca ccttcacggc cgtttgtaac ttccttaacg tcatctttat
      841 agtgtttcaa gcttgcgagt tcaccatcat agataacgac accatcacgg ataacacgga
      901 ctttagagtc acgggcaacc ttaccgttga taaccataaa tccaccgata gttcccactt
      961 tagacacctt gaaggtttca cggataaccg cttcaccaat aactttttct tcaaattctg
     1021 gatcaagcat ccctttcata gcttcttcca tctcttcgat aaccttgtag ataatgctgt
     1081 gaagacggat ttccacatcg tcagcttctg cttgttgacg agcttgtggt gtagggcgta
     1141 cgttgaaacc aacgataaag gcatttgaag cttcggcaag ggtcacgtct gattcgttga
     1201 tagcaccgac cgctgagtgg acgatagtca ctttgacacc ttccacgtca atcttttgaa
     1261 gtgaggcaga aagggcttca acagaacctt gtacatcagc cttgatgata acattaacag
     1321 atttgagttc cccagcttta agggtatcaa agaggttttc aaggctaaca cgttgggtag
     1381 cttgacgttg tttcatgagg gcacgtttgg cacgctcttc acctgctgca cgcgcagatt
     1441 tttcatcctc gtaaacggca aagtggtcac ccgccatcgg tgcttcgttc aaacctgtga
     1501 tagagactgg tgttgatggt ccagcaactt taacacgacg accaaggtcg ttggtcatag
     1561 cacggacacg accgaaggta tttccgacaa cgattgggtc ttgaacattc aaggtacctt
     1621 gttgtacaag aagggttgcg accgcacctt ttcctttatc caagcgcgct tcgataaccg
     1681 taccgattgc acgcactgtt gggtctgcct tgagttcttg gatttcagct acaagaagga
     1741 ctgtttccaa caattcttcg atattttggt tgaatttagc tgagatttca acaaattcag
     1801 aatctccacc ccaagcggtt gacatcacac catgctctgc caattcaccg ataacgcgtt
     1861 ctgggttagc acctggttta tcaatcttgt taatggctac gatgattgga acgttagctg
     1921 cttttgagtg gttgatggct tcaatagtct gaggcataac cccgtcatct gccgctacga
     1981 ccaagatcgt aatatcggta acagaagcac cacgcgcacg cattgatgta aaggccgcgt
     2041 gtcctggtgt atcaaggaag gtaatcttct taccattttc cacgatttgg taggcaccga
     2101 tatgctgagt aataccacct gcttcacctg tcgcaacacg tgagttacga agagtatcca
     2161 aaagggttgt tttaccgtgg tcaacatgtc ccatgatagt aacaactggt ggacgctcaa
     2221 ccaattcatc ttcattgaga taaccatctt cgacaaagaa acgttcgatg tcagcattat
     2281 ccacttcaac cttttgtttg gcttcgatac cgtaatccac catgaggagt tcaattgttt
     2341 ccccatctaa ggattggttt tgtgtggcca tgacacccat catgaaaagt ttcttaacga
     2401 tttcagctgg ttcacgtttg atacgttttg cgatttccgc aacggtcata ccatctgtat
     2461 attcaaattc tgttggatat tcaaattctg ttggcaattc atggaattta cgctccgtaa
     2521 caggttttgg agtctgatta cggttgttct tgttattgcc ttttttgttc tttttgttgt
     2581 tattccagtt actattcttt tgatttctca cttgattttg actacttcga ttcttttgtt
     2641 gttttctagg accatcttct tcatgatcat aatcgtcacg atttttgtct ggtcgagctt
     2701 gttttttacg acgtgtatcc actgcaggtt cttttttctc agggacgact tcaaccactg
     2761 cttgaacttg ctgtgcttgt tcagctaact tagccgcttc ttcaaagatt tcctctggtt
     2821 ccttgcgttt gttagcttga gccaaggctt ctttagcagc ctgatactgc ttgaagcgtt
     2881 cctcacttga acgagcgtac tctgcatttt gctctgcttt tagggctgct gcacgggctt
     2941 taaagtcaat acgtggagcc gcttgatttg aacgtttgtc ctcttgctga cggcgctcat
     3001 ttctacgttt ttgctgacct tgctgcttct tagcttggtc attaaagcga cgattgtcgc
     3061 ggttgctttg accttgtttt ccaccattac ggccatcgtt tttctgacgg tttccgtttt
     3121 gttgttggtc acggttattg cccttatttt gcttgcgtcg ttctgcctgc tctttagcac
     3181 gggcttcacg ctcagccttg aaattacggc tttgcggttt cgctgctact ttttctgttt
     3241 tcggagcaac tggctcagcc ggttttgcct cttccttagc tacagctggt ttagctggct
     3301 cagatttttc ggttttcttt tctgcactta cttttggtgc tgcaggtttt gcttctactt
     3361 tcggagcagc tgcaggctta aagctggcag caatttttgc agcgacagct tcttccacac
     3421 ttgatgagtg gcttttcaca tccaagccca actcttttgc acgcgctaca acttctttac
     3481 tttcttttcc aagttctttt gcgatttcgt acaatctttt cttagacaaa tcatgtcctc
     3541 ctcttctatt ccataagaga cctcattttc tttgtaaatc cagcatctgt tacagccaaa
     3601 acctttctcg atttcccgac tgctatgctt aattccagtg ttgaaaacac ggttacaatt
     3661 tctacttgat aataatgact tttatcttga atcttcttgg ccagattggg tccagcatca
     3721 tgagctagaa agaccaactt ggccttgccg tcttgaatgg ccttgaccac caattcttca
     3781 cccgatatga tgcgccctgc tcgctgagca agccccaaga gattacttat cttttgctta
     3841 ttcaagtccc aactctcttc ttttcacttt gtgatccaca taagcgatca actcgtcata
     3901 aaagctttct tccacttcca tgctaaagct gcggttaaag accttcttct ttttcgcctc
     3961 tagggcttct gcattgtcta gtttgatata agcgccgcgg ccattggcct tgcccgtagg
     4021 atcaataaag acttgtcctt ccttgttctt gacaatgcgg agcaaatcac gcttatcaat
     4081 cacttcgtta gacacaacag acttgcgcaa agggattttt cttgttttca tctttccctc
     4141 ctctagcagc ttttattctt ctacagtatc gttttctact tccaactcta ctgaagcagc
     4201 gtcttccatg gcttcaaatt cgctagcaga cttgatatcg atacggtaac cagtcaagtg
     4261 agccgccaag cgcacgtttt gtccacgacg accaatggca agagaaagct tgttatctgg
     4321 aacaaccacc aaggcacgtt tgctgtcgtt ttcatcaaag ataacttggt caacctcagc
     4381 aggagcgatg gcattgtaga taaattcagc tggatctgct acccactcga taacatcgat
     4441 attttcttcg attggtacca tgcggtcatt tttagcatcg taacgagctg ggtggaattt
     4501 gctagtaatc ttcttgatat tagcaccacc acgtccaacg attgtaccga tagcatccac
     4561 gtttggattg tggctacgaa cagcaacctt cgtacggtca cctgcttcac gagccacgct
     4621 catgatttca acagttccat cataaacttc tggaatttct tgctccatca aacgtttgat
     4681 catttctgga tggctacggc taacaaagac gttcacacca cgagggttgt cttcaacctt
     4741 gtaaacataa acttcgatac gatcatgaga agcaaaaact tctccaggaa tttggtcttg
     4801 ttttgacaat tgggcttcga tgctaccaag gttgacatag ataaagcggt tgtcaaagcg
     4861 ttctactgta ccagacatga tttcttgctc atgttctttg taagtattgt aagtgatggc
     4921 acgtgtttgc ttgcgcattt tttccatgat ggtttgtttg gcagattggg ctgctacacg
     4981 accaaactca gctggtgctt cttcaaactt gattttgtct ccaagttcat aagctgaatt
     5041 aatggcaaga gcatctttca agctgatttc caaacggcta tcaaatactt catcaacaac
     5101 ttcacggaca gtataaactg taaagtcacc tgttttttcg ttgaagtcaa tagctacgct
     5161 gtctgactga ccatagcgtc tgcgataagc ggaacgaagc gactctacta ctgcgtcgat
     5221 gatatcttct tttttgattc ccttgtcttc ttccaaaatg cggaaggcct ctagcatttc
     5281 tttactcatg ttttcttcac ttttgaatcc tcaaaagcta tcctttcttt ttctataatt
     5341 taactgctaa acgtgctttt gatactaaac tgtatggaat tcggacggtt ttcttacgcg
     5401 tcttgtccat atattccata gtcaactcgt cctcttcgaa ggccaacaaa gttccttcaa
     5461 agaccttttg cttatcgatg gcttggtaga gtccgacatg gatgtatttt ccaaccgctc
     5521 cagcgacggc atccttggtt ttcaaaggac gttccaagcc tggactggta atttctagga
     5581 aatattgttc tgggaaggga tctggcttga tggtgtctag gacaggactg ataatttctg
     5641 tcaagtctgc cgtgtcgttc aaggtaattc cttcgggttt atctacaaaa atactgagaa
     5701 tcatgtcact gccaatcttt ccatactcga tatccacgag ttcaaaagga gcttctatga
     5761 caggttctac aacttctctg actaattcta cgattgttgc gattgcgtcc acctcctcat
     5821 aagcaagagg cgaagatatt tccccgcctc acttttcata ttcttactat cagtatagca
     5881 cgtttgccaa cttatgtaaa gcaaaagcac ttgtacagcc taattttagg ctatctctta
     5941 aaattctgcc tcaactcggt agataacttg ccccttgttt gagaattttt gctcgtattc
     6001 tgtcatgaca ttgccttcaa aatcactggc atgcaaatct agccagacac cattgagttt
     6061 catgccatat tgagaaaagc tcactaaact gtactcaaac aagccacggt tatccgtctt
     6121 gaaatgaatt tctccatttt caggcaagat acgtttgaag gtgtccaaaa aggtcttgta
     6181 ggtcaaacga cgcttttcat ggcgtttttt cggccatgga tctgaaaagt tcagatacaa
     6241 gcgatcaatc tcaccgtctt caaagtagtc agttaagtca gaaccatcta cccacaagag
     6301 cttgatgtta ggcactccaa cttcaagcac cttgtccaaa gcgtagctca aaacagactt
     6361 ttgaatatca atcccgatat agttgatgtc agggttttgc ttggccatac ctgaaacaaa
     6421 ggcacccttt ccacttccaa cttccacatg aatgggatta tcattgccaa acaagtcccg
     6481 ccattttgcc ttggcttcca agggattgag gaccacatac tggggatttg cctctagtaa
     6541 ttctgttgcc cctttacgat ttctaactct catcttctct ttccatactt gtctcggaaa
     6601 tgacgcaaac catgaatctc ccgattgaca ttttctaaat cttggttcat ataatacttg
     6661 gaaatctgac tcaaataaga caattgacca taccaataca atttacttaa taccgtttga
     6721 ttgtacttgt aaccgtagta ggtcaaccat tccttccact gatgttctga aatataatgg
     6781 cagagcatat gggccacatc aaacatgcga tcggtcaagc gaaccgaatc ccaatctact
     6841 aaataaatca agccactatc tgtctcaatc caattactat gtcgtacatc tccatggaca
     6901 atggtcgcat ggtcctctct aaatcctgga atagtctgac gtaaatcagc catcacttca
     6961 ctgataaaat gatttttacg caaagcatct ggagccgttt cctgccaaga ctgtagtaaa
     7021 tctacaggtg tttccatggc atagcccaaa cgactcaatt gtgtcatcaa cggacgtgag
     7081 cgatgaagac gggttaaaat attgacgatt tgcttacgat tcatatcata gggggtcaat
     7141 atcttgcctg tcaaccattc ttgagcacac atatcacgcc catctgccaa acgacgactc
     7201 cataataatt gtggagcaat ttgttctcta gctagaccag gtaggattgg agaggtgttc
     7261 atttttacaa agatgcgctt cccatcagga tagctaccca tataagcctt gccacttttc
     7321 ccaggtatgg gagtcagtgt tagctcatta tcacccaaat ccatttcttt cctccgtata
     7381 aagtttcctt actattctac tagtttttgg cctattcgtc aaccactcta acccgattct
     7441 caaagaaaag cctctggatt ggcttgggta tcattatagc ttgaaaaagg taagcaccgt
     7501 cttctgctta ccttttcata atttttataa ataatataag agtggccaac tgttgtaaag
     7561 catatggact agagtagaaa cccataggtt ttgactcttt ttataagcaa agcccagcaa
     7621 caaaccccca agtagataaa aaataaacga agggacatta gaaggtccat gcatgaaaga
     7681 aaagagagag gaagttagca caagccctaa ccaagaattg tcaaaaaccg caccttgaag
     7741 aagtcctctg aaaatgagtt cctcctggat ggggccaaaa actgaggtag ttaaaatcaa
     7801 agacagggaa attcctctgc tgacttccgc caagtgttgg acccctgagc cagaagaaac
     7861 agcgaagaaa tgaatataaa ccagcgtctc aagtacactt agaagaaaga ttgcaatgaa
     7921 aagcaaaagt tgtttcttgc ttaacatccc aaaagaaatc atttcaaact ttctagcata
     7981 agcaacactc agcgaggtta caagaagact tacaagaatc aatgcagatt cattttgaaa
     8041 aaaaccccca tggttaatcg tataaggaac tgtaatgaca attattagta ctaaaaatcc
     8101 aaaacacaag gcatgaaatt tatcaaaaaa ctccataaaa ttatcctcct caacaaacag
     8161 acttcctaca cgtcattctt tagttctagc ctttccaaaa caaaccattt tatactcttc
     8221 gaaaatcaaa ttcaaaccac gtcaacgtcg ccttgccgta ctcaagtaca gcctgcggct
     8281 agtttcctag tttgctcttt gattttcatt gagtattagt aaccaaaatc cgaccacata
     8341 gccagcccct atgaatatag ccattaaagc tagcatggaa tttaggaaat taaaaaccac
     8401 cgcagataca aaggttagca caaaaacatt aaaagcaatg gtgtcagaag ccaagactag
     8461 aatatagggt gtcaaccgat ctaaagtttt ggaatctagg aaaaataagt gtttatacat
     8521 gatgacctcc tctatggctg aaaagcaagc cttttgtttt tttaccccaa gaccctatgt
     8581 agaaaagtga gcaaaaacgg gaaggtcgct acaatattat tgatcacatg caccgcatag
     8641 gatggataaa tgctcttggt atagcgggtc aaaccagcaa agatgattcc aactgttgca
     8701 aagacgaaga tatctaacag actaggcagg cttgaaaaat gagggagagc aaataaaata
     8761 gaaggaagaa gcaaatcaag accaaatcgc gaatgcttaa agaaagcatg ttgcagtaat
     8821 cctctataaa tcaattcttc catcagtgga accagaaaga acagggctat ataaatacct
     8881 agctctgcaa agttagtccc actataaccg atcaatacag cccaaccttc agcagttgac
     8941 tgaacatgtt tagctgtctg aacgttaaaa gagatctgga gcactaccac taatactgtc
     9001 aaaatcgaat accaaagcca tttttttctt ggaatgtgaa agagataacc atgacctgtc
     9061 ttaaccagaa tccaaatcat gactccgcta aatagcaaac tcaagaaatt ttgaatccag
     9121 acgaaattgc caatctggga agaaaattgc caataatttt gaataataag cgtcatctga
     9181 gaaagaccaa atacgaaaaa taagtaagag aaaactgcac ttattttgaa tagaagttga
     9241 tactttttca tagaaatcct ccctactatg acctcacctt gtcaggctct actgctgtaa
     9301 gattaagaag acagtttgtt ttttttaagg ctaacctgac tactagataa tagatacatt
     9361 aaggcattaa agacaatgaa aatatgtcca tagaataaaa tcaacctcgc atccaaacca
     9421 agataaagtt tgattatcaa aaagatgagc aaaagaattt gaaaccataa ggtttttcca
     9481 aaaataaatt taaagcgatt tcgaatatct acttccttga tttttaccgc caccccttta
     9541 ttagcaagaa ggaaaactcc tgcttcaaac aaaccactgt aaagaacaag ccacccaata
     9601 gatacgatag agatttgtaa aaatgtccct aaaagaatat ccaacacact actcaagaaa
     9661 ataacaaaaa ataatctgta tttcatatta aatacctcca ttcatttatt tcactaacaa
     9721 tttaatagag ccttctactc aaatatcctg tcagaaaagg atagaaagct actttttata
     9781 atacttcaag ccccacatga gcagaagcgt gataaacaag cagagaatac acctatataa
     9841 gcgattagtt gttgatagaa ttctgtttct gaaatacctc tatacaaaca aatgacaaac
     9901 ataaaatctg ccaagccgat aaacataagt tgattggttc taggactaac caaatcatca
     9961 tttacttata tttaagagta tctcttttat gttaatgtat gttagcactg aaaagcaaga
    10021 caggccaata atatttaaaa tgaacagtaa cggggttaag tctctaaaaa aattatctac
    10081 tgacactaca agaaatacta tacatattat agtcgaaact atctttttct tatccataat
    10141 tatttactcc tttcctaaca aatccaactt atcaatcaag agcgattttt aacataatgt
    10201 agcagcaccc gttgcaactt tgacaagttt agtatatcat tgttttttaa aatttttcat
    10261 ccaaatcttg aattgtcatc gaaacctcct aaattgcaaa aacttcatta gcccctactt
    10321 tttataatac ttcaaacccc aaatgagtag aagcatgatg atcaagcaaa gaatagcacc
    10381 aatataagcg attagttgtt gataagattc tcctgctgtg atacctctat acaaacaaat
    10441 aatagacata aagcctgtca agccgataaa catgagttga ttggttctag gactaaccaa
    10501 atcatcatct tcaaactctc ttaatctcat ttccctagta agataaacag taaccaaaat
    10561 agaagtcaag ttaataacta ctaaaagaaa ttggaaaact gacgaaatag aaatagataa
    10621 gtagaaacaa gcaaaggcaa ctgacccagg aacaatctca caaagaatat gattcttttt
    10681 aatcaagaaa atctttcatt tcttttcttt ctttttaatt aaagaaaaat agatcataac
    10741 cgcaatcata taggctatgg tataaaatag attataccaa atactctccc taagcggata
    10801 aagaaagatg gacatgatca gatacagaac gaaaataatc agtatttttt tcttcataag
    10861 ttttcctcct aaatgtgcga tttatcttag ttgagcaaga acatttacac tgctagtata
    10921 gcacttattt tgaccttgga tcactcaaat cataaatggt catcaaaacc tcttgaattg
    10981 taaaaattaa aaaagcaagc atgaaaaaca tactttcctc tttatattgt attgatacca
    11041 acttgtttgt agacttttca tcctgctatc acatatcatt ttgacaggcg aaacaatatt
    11101 aaagaaactc ccctgtaaat taagctagca aatacagggg agaaatttat tttttagaga
    11161 gtactatccg tatccttttt ggaagatttt gaaaatattt ttctaattaa gtcatccata
    11221 taaggaccaa atataccaac tactaaacca ataataaaac ttttaaaatc cataattacc
    11281 accaacatgt tgctgcatag gctacacctc caagtatagc tccacctgca gcaccagtta
    11341 cacctattcc tatagcaaat ggtcccaata gaaatgtcaa accgttgttg cacacccatc
    11401 aattgcgcca tatgcaaccc ctgctgcaca actaattttt cttccccaat caatatctcc
    11461 accttcaacg caagcaagca tttcattatc cataacagaa aattgtgaca tcatttttgt
    11521 attcatatag tatgtcactt ttcagttacg gaacaagttt aatataaaaa ttatcaaaaa
    11581 aacataggca ataaagagaa aaattaattt atcatagatt agaaataata tgacaaaaca
    11641 attcaatgat gttaattcaa tagtcttttg ttttttatca gagatactta tggatagata
    11701 aataagatag gtttgaaaag cgaagagaat aataaagaat atagccttca taaaatttag
    11761 ctttcatttt tatgatgtag cggtataggc taaatatcca caaaccactg ctcctccaat
    11821 tcctcctatt gcagcgcccc atggtcctag aattttccca tatttcactc cacccgctgc
    11881 acaacctaaa gcagcaacta cagctgctcc tccaacacct gctttggcaa aatctcccca
    11941 attgcatccg ccaccttcaa cgcaagcaag catttcagta tccataacag aaaattgtga
    12001 catcattttt gtatccatga caaatactcc ttttttaaaa aactaaaata aatcagaata
    12061 gaatcctcat aattttacta taagtcttac caacttagtc ccaatttatc accaaccata
    12121 cctcctaagc atgttaatcc acccccaatt gcaccaatgt gtgctccaac aaatgcacca
    12181 gcaagtccag ctactcctaa agtggccaaa cctgctccag ttccaccagt tataattccc
    12241 gtagtgactc ctgtaatcag tgcattttga caatcagtgg agctataccc cccttcaact
    12301 ttcgcaagca tttcagtatc cataacctct aactgtgaca acatttttgt attcatgatg
    12361 aatacctcct ttttattttc aatttgttac caaagtctta aattcaataa acaaatagat
    12421 tttttatagt atctttttga ttttcttaaa aaagtatata cgtctactat cttcttaaag
    12481 gtagcagtac ctatttttta gtctaagatt tcaataatct tgagtatcta aaatatctta
    12541 atttcgttat tctccttgca ataaaaagtt ttactatact atttattaac ttgcagaaag
    12601 caaaaaatat tagtaaataa tagtttatag ttaagttttt tattcctacc aatccatcaa
    12661 ctaagtaaag catcaacgat tacataaacg attgataata taattaaaat tttgctaact
    12721 atcttattct catcattctt agataacttt gatattttgt aagtaagtaa ataagacagt
    12781 aaattaatag cgataataat actatattta agaatcataa tcttacaaag aggacataat
    12841 tcctgaacct acacaaataa gtgttgctgc tcccccagtt atcggaccag tcgcagcagc
    12901 taatagtact gctccaatac aaccaccgat tgcagatcct aaattgcctc ttcctccact
    12961 aactatttcg agttcttcat tatccataat ctcaaattgt tccatcattt ttgtattcat
    13021 gacaaatact cctttttctt tttttatttt tgtcttgttg taactttgat aagtttagta
    13081 tatcatcgtt ttttaaaatt tttcatccag atcttgaatt gtcatcgaaa cgtcttgaat
    13141 tagctttttt atttcaagcc acctctaaat gtttaaaaaa aataatttct aatcactttt
    13201 ttaccattca ggaagtttta atgactattc aagatttcat aaaatatgaa cttagtttta
    13261 tgacataata gacctatcca ctatatgaaa agaattgcca atgacttctt ataaacgtac
    13321 atttgttcct caaatagatg cgagagactg tagtgtcgct gccttagcct cgattgctaa
    13381 attctatggt tcagattttt ctctagctca cttgagagaa cttgcaaaga ccaataaaga
    13441 agggacgact gctcttggca ttgtaaaagc cgctgatgaa atgggctttg aaacaagacc
    13501 tgttcaagca gataaaacgc tctttgacat gagtgatgtc ccctatccat ttatcgttca
    13561 cgttaacaaa gaaggaaaac tccaacatta ctatgttgtc tatcaaacaa agaaagacta
    13621 tctgattatt ggtgatcctg acccttctgt aaaaatcact aaaatgtcaa aagaacgctt
    13681 tttctatgaa tggactggag tagctatttt tctagctccc aaacccagct atcaacccca
    13741 taaagataaa aagaatggtc tactaagcaa gcttccttcc tctgattttc aaacaaaaat
    13801 ctctcattgc ttacattgtt ctctcaagct tattagtcac tattatcaat ataggtggtt
    13861 cttactatct ccaaggaatc ttagatgaat acatcccaaa tcagatgaaa tcaactttag
    13921 gaatcatctc agttggtctg gttatcacct atatcctcca acaagtcatg agcttctcca
    13981 gagattatct cctaaccgtt ctgagccaga gattaagcat tgatgtgatt ttatcctata
    14041 ttcgccatat ttttgaactt cccatgtctt tctttgcgac acgtcgtaca ggagaaatca
    14101 tttcacggtt cacagatgct aactctatta tagatgcctt ggcttctacc attctttctc
    14161 ttttcctgga tgtttctatt ctgattcttg tagggggcgt cttactggca caaaacccta
    14221 atctcttcct tctttctctt atttctattc ctatatacat gttcatcatc ttttctttta
    14281 tgaagccttt cgaaaaaatg aaccatgatg tcatgcaaag taattctatg gttagctctg
    14341 ccattatcga agatatcaac gggattgaaa ctataaagtc gctcacaagt gaagaaaatc
    14401 gctatcaaaa tatagacagc gaatttgtag attatttgga aaaatccttt aagctcagta
    14461 aatattctat tttacaaaca agtttaaagc agggaacaaa attagttctg aatatcctta
    14521 tcctatggtt tggcgctcaa ttagtcatgt cgagtaaaat ttctatcggt cagctgatta
    14581 cctttaacac acttctttct tactttacaa ctcctatgga aaatattatc aacctccaaa
    14641 ccaaactcca atctgcgaag gttgctaata accgtttgaa cgaagtctat ctagtcgaat
    14701 ctgaatttca agttcaagaa aaccctgttc attcacattt tttgatgggc gatattgaat
    14761 ttgatgacct ttcttataag tatggttttg gacgagatac cttaacagat attaatctca
    14821 cgattaaaca aggagataag gttagcctag ttggagttag tggttctggt aaaacaactt
    14881 tagccaaaat gattgtcaat ttctttgaac cctacaaagg acatatttcc atcaatcatc
    14941 aggatattaa aaacattgat aaaaaagtct tgcgccgtca tattaattac ctaccacaac
    15001 aagcctatat ctttaatggc tctatcttgg aaaacttaac tttgggcggt aatcatatga
    15061 ttagccaaga agatattcta agagcttgtg aattagctga aattcgtcaa gacattgaaa
    15121 gaatgcctat gggctatcaa actcagctct ctgatggagc tggtctatca ggaggacaaa
    15181 agcaacgaat agccctcgct cgtgctcttt taactaaatc tcctgtttta atactagacg
    15241 aagctactag cggtcttgat gtcttgactg agaaaaaggt tatagataat cttatgtctc
    15301 taactgataa aaccattctc tttgtagccc atcgtctcag tatagccgaa cgaaccaacc
    15361 gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg tagtcaccaa gagttaatgc
    15421 aggcgcaagg tttctaccat catctattca ataaataagg agaatgtcat gaatcctaat
    15481 ctttttagaa gcgtcgagtt ttatcagaga cgttaccata actatgcgac agtgttaatt
    15541 atacctcttt cattactatt tactttcatc ttgattttct cccttgttgc cacaaaagaa
    15601 attactgtta cttcccaagg agaaatcgcc cctacaagtg tcattgcctc cattcagtca
    15661 accagtgata atcctatcct agctaatcat ttagtggcaa atcaagtagt tgaaaaaggg
    15721 gacttactca tcaaatactc tgaaacaatg gaagaaagtc agaaaactgc cttagcaact
    15781 caattacaaa gacttgagaa gcaaaaagaa ggacttggaa ttttgaaaca aagcttagaa
    15841 aaagcgactg atcttttttc tggcgaggat gaatttggct accataatac ctttatgaat
    15901 tttactaaac aatcccatga tattgaactg ggtatcacaa agactaacac cgaagtttca
    15961 aatcaagcta atctttccaa tagcagttca tcagctattg aacaagaaat tacaaaagtt
    16021 caacaacaaa ttggagaata tcaagagttg agagatgcta tcataaataa cagagcacgc
    16081 ttaccaactg gcaatccgca ccagtcaatt ttgaatcgtt atcttgtagc ctcacaagga
    16141 caaacacaag gaacggcaga ggagccattt ttatctcaaa ttaatcaaag tattgcaggt
    16201 ctggaatcat ctatcgcaag cctcaaaatt cagcaagctg gtatcggaag tgtagcaact
    16261 tatgataaca gtttagcaac caaaattgaa gtactccgca ctcagttttt acagacagcc
    16321 tcacagcaac aactaactgt ggagaatcaa ttaacagaat taaaagtaca actagatcaa
    16381 gccacacagc gtttggaaaa caatacctta acctccccaa gtaaaggtat cgttcatctg
    16441 aacagcgaat ttgaaggtaa aaatagaatt ccaactggta cagaaattgc tcaaatattc
    16501 cctgtcatca cagatacaag agaagtacta atcacttact acgtatcttc tgactatcta
    16561 cctctactag ataaaggaca aactgtaaga ttaaaactgg agaagattgg aaatcacggc
    16621 accaccatca tcggccaact tcagacaatt gatcaaactc ctaccagaac agagcaagga
    16681 aatctcttta aattaaccgc tcttgcaaaa ctatctaacg aggatagtaa actcatccaa
    16741 tatggcttac aaggtcgcgt cactagtgta actacaaaga aaacatattt tgattatttc
    16801 aaagataaaa ttttaacaca ttctgattaa ttttcagata acactctata actatttatt
    16861 atcttatcaa aaaggagaat cataacatgg ataagaaaca aaacctaact tcatttcaag
    16921 aactaacaac taccgaactc aaccaaatta caggtggagg attgtgggaa gatttattat
    16981 ataacattaa tagatatgct cattacatca cataagaact tcatcatcca atacaactat
    17041 aaaaaaataa gaccgagaaa caagtactct cggtcttatt tttcatcatt ctgtatgtat
    17101 cacagtaagt acctgacgaa agacttgatt ttgacaggtg gtatttagac tggtattagg
    17161 atggctttcc acaatcttca tgacggtata gagaccaact cctctctcct cccctttaga
    17221 actggctcca aaggagaaga tttcagaaat atcgatgccc tcttctttga tggagttttc
    17281 gatgataaag gtctcctgtg ctccattttt taaaaaggcg attgaaacat gaggttgact
    17341 agcttccaca ctggcttcaa tagcattgtc acaaaggata gacacaatgg ttagaaaatc
    17401 aagtagactc atcccctcga cctgaatctc ctcaggaact tcgacattaa agacaatgtt
    17461 cttatctctg gcttttaaaa atttccctgc tagaagactt ttgagggctt tatcacgaat
    17521 atttaccaat ctgcccaggt catatttatt gttctgcaat ttctgactgg aatcctttaa
    17581 gacggagcca tagacctctt ttatctgctc catatcctcc tcttcaatgc ccagacgtaa
    17641 gctagtcaag aggttggtat aatcatgacg aaagctccgt acttccttgt aaagctcctc
    17701 tatatgccga ctatagcgtt ccatatctct atagcgcagg gcctgctctt gttccaatct
    17761 ctcatagagt ttttccttca aataggtatc caatttcttg ataaccccca taaaaaagag
    17821 taggtaaaag actaggatga gatggcgaac agtctttgat tgaatacttt gttcatattc
    17881 aaaaaaagac agactttcca tgactaaata gtagccaccc attatccagt taatctgagt
    17941 cagggacttt tgaaaggctt tatcgagaat ctcctttctc aagctagtaa aatcgtagtc
    18001 caaccatttc aaaaaagcta gagaaatgaa gaaattgaaa attattatac ataacccagt
    18061 aaatgagtag ccatcatata cttgcccttg tcccaaaaat ggaagcacaa aataggagac
    18121 tcctctataa aagagattca ccaatatcat tggaaagaga ccataaaaga aaaggagttt
    18181 tttaggaagc cctctcaata ataagaaaga taagcctatg ccgtacaagg gttccataaa
    18241 ataagatagg taaacatttc ctactatata gctaatcatc acaaaaacaa aggccaacag
    18301 tatcttcaaa agaaaggcct taaaaatcct ctcgaaagta agatcaattc catccacctt
    18361 aaagaagatg acaatttcta gtccattagt aacaagtgta tacaacaata tccaagcaat
    18421 gttcataaat tctcctagct cagtgtaatt tattgatggc ctcagacact tccctgacct
    18481 tataacgggc gattagacaa cttccaccat tgggaaagaa aagcagtttt tctttcttat
    18541 ccaaatgcac cacatttgca ggattgatga gaaaagagcg gtggcactgc aagagacggg
    18601 gctcctgctt gaaaacctcc tctaaactcg ctgtaaattc cagcctgtct gtcttggtat
    18661 agagaataac acgatgggct ctgggcgacg tttcgagata gtaaacctct ttaaaaggat
    18721 actgaaattg ggcaaatttt gatttaaagt aaaagcaatc ttccgccaga cttttactat
    18781 cttgactatt ggcatagagg agggctgtct cgatccgaga ttcaaactcc tctgctgaca
    18841 aggccttatc aatgtagttc aaagcagaca cttggtagcg aaaagacagg ggcataaact
    18901 ccgagtgagt cgtcacaaag acaatcaggg cataaggatc ccgatcccga atctttctag
    18961 ccacttccag tcccttcatc tcttcatttc gaatctcaat atccaaaaag aatagctgat
    19021 gggccccctt ctcatgcact tcagccagca gttggtccgg cttgccaaat acctcaaaag
    19081 agctaggaat gatatgatgt gctttcaaaa gtttctcaat cgtcgtttca attctagtct
    19141 gttgggaaaa atcatcctct aaaacaaata ttctcatctt tttactctcc ttattttaac
    19201 catttttgac gaatttctct atagcgacgt ctggcatact tgacagcgta ttgaccttct
    19261 tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt ttaatttatc aagattaacc
    19321 aaacaatttc gatgacatct catcaaggtt tccccacatt ggttctcaag attacttaaa
    19381 ttttgaagca tattaaaact agcttcttct gtaacaatct gtacggtatg ggctttagtt
    19441 ggatgtgttt ggatatagta gatatcgtcg acgtttactt tatagactgt tttctgcgtc
    19501 tgaataatca tatgtttcat tggattctcc tcctaagaaa agaataacag aaaaggtcta
    19561 gcccaagccc acccaatcct aaacagtctt tgaaagctcc taaaaggatt atttttctac
    19621 aacatcatga tgagcttaca actattttat cataaaattc actcagcgca attcaagaca
    19681 tttcaatgac aattaaagat ttgaataaaa aaaaagaatt aaaaatgata aactaacagt
    19741 atcaaaacac agttgccaga agtaagactg gcacccagat taaaggaggc attcccatga
    19801 cagatacaga ccccatcaaa agagctcata ctttgattac tgacttaaac aaagcctacc
    19861 aagcatgcaa acaggcaagc gctgacgacg tccgctttca ggagcaatta aactctattc
    19921 ttggttttct agccaaggct gaaacagtgg ataatcgatt cttgattgaa ctagaaaaat
    19981 tttaccagac ttccagtctt ctcatgggac tcagcgctct tgatccagat gctccaactc
    20041 gcgccgcttg gcgggcctat gaccgcttcc actttgacca agtcaagacc aagttaatac
    20101 tcaatgaaaa tcaaagagca aactaggaag ctagccgcaa gctgtacttg agtacggtaa
    20161 ggcgacgctg acgtggtttg aagagatttt cgaagagtat aagtctctac ggaccaacca
    20221 ttatcctgta gtaacaaaaa agaagctgag acagactgaa ctcaacttct tttttagtgt
    20281 cgtatcagca atgttagtcc tgcatctgac gttttacctg ataaggcaaa tacaagacta
    20341 gtaaaaccaa accagctcct agtaaggcta gaagggccag tttttcttgg aaggtaatca
    20401 acccaacaac taattccaca agtaaaacaa aactggtcaa tcctcgaact acctcctgta
    20461 agcctttttc cttttgcccc ttgtccagcg gaaagagttg ggtcaaatac tggtagtcaa
    20521 aggcatgata gagggccagc aactggaaga gcaagaggta gttaaagaga actaccactg
    20581 ctgtcgcaat ccaagcttgc tcgataaaaa cctgcgccag tacggaaagt aagagaagac
    20641 gaagactgag agcaaagagg tcgccatttc gcagataaga acgcagatag agattttgcc
    20701 aaatcttccc aggcaccttc tgaacagcct ttaaaataaa gtccagatag gcacgacgct
    20761 taacgctgtt tgaaattccc ttgacctgcg taaagagggc aaagaaacga agcaagactt
    20821 gcttacgctt gctttcttga gaaataagat agtcccagtc cagtccagtt tcagtgaaaa
    20881 atttgctggc cttttgacaa aagtggaaat attttcctac ccccaataaa agcacataga
    20941 gcagaaaaac tggcaagcca taacccattg ctaaaaataa aggcgcaaat aaaagcaaga
    21001 agagggtctg gacaaaaatc caaaagacta gggaaatgcc agtttgacgc ttgagatgga
    21061 gcttaatttc ctcttctcca actaagagaa agagcttgtc tggagcctcc atataggtgg
    21121 caattcctcc ccaaagtaaa agtaaaacag acgtaattcc tacaaacaaa aggataggcc
    21181 aatgattttc aggaaaatgt tgtaagagtt gactgtactg gtaggctaga aagcccaaca
    21241 ggacaagcag gaacaagaca aagtggtcat tgagcacata gcgcagataa ccaagacact
    21301 ccttacgaaa ggcctgcttt ctctttaaaa acaagtcttt cataggtcct cctcttttgt
    21361 cagagccaag taaatatcat tcaaactagc ctcaggcata tcaaaggctt cgcgtagttg
    21421 caggagattg cctttggcac gcacctctcc cttgtgaaga atgacaaagg catcacacat
    21481 cttctccgcc gaatccagca cgtgggtact catgagaata gacttgccct tttgcttctc
    21541 cacttccaaa agctgaatca aatcagaaat agctagcgga tcaagaccaa ggaaaggctc
    21601 atccacgatg aaaagacttg gatccaccac aaaagcacag ataatcatga ccttctgctt
    21661 catccctttt gaaaaatgaa cagggaacca gtctaatttc tggtccagac ggaacatctt
    21721 taacaagggc tctactcgtt cgaaagccac tttttgctca ataccgtaag ccatagcaac
    21781 cgtttcgata tgctctctga gggtcaattc ctcatacaga ctaggcgtct caggaatgta
    21841 gccaatctgc ttgcggtagc tagtcgcatc tccttgcata gtcaggccat tgatattgat
    21901 ggagccacta taaggtgcca acagaccgat aatctcattg atcgtcgttg atttcccagc
    21961 accattgaga ccaatcaaac cgaccaactg cccactttca acagtaaagg acacatcttt
    22021 caaaacagga acatgaacat agccacctgt caggttttta atttctaaca tattttctcc
    22081 aaatctggta taatgtagct atattatatc aaaattcagt acagtagagg tagattttat
    22141 gtcagattgc attttttgta aaatcatcgc aggggaaatt cctgcttcaa aagtatatga
    22201 agatgagcag gtccttgcct ttcttgatat ctctcaagta acactaggac acaccttggt
    22261 cgtgccaaaa gaacactatc gcaatctttt ggagatggat gctacgagcg ccagccaact
    22321 ctttgcccaa gtaccaaaag tagctcaaaa agtcatgaaa gtcactaagg ctgctggtat
    22381 gaatatcatt tccaactgtg aagaagtcgc tggtcaaaca gtttttcata ctcacgttca
    22441 ccttgtgcct cgctacagtg ctgacgatga cctcaagatt gattttatcg cccacgaacc
    22501 agactttgac aaacttgctc aagtcgctga aaccatcaaa aacgcttaag gagttgctat
    22561 gaaattatcc aacctactgc tatttgcagg agctgcagcc ggaagttatc tggttacaaa
    22621 aaatcgccaa accatcacag atgaagtctt gaataccact gaccgcgttc aagctatcaa
    22681 ggacgatgtg gatattatcc aaaacagcct gcaaatcatt aaccagcaaa aagaacttat
    22741 caaggaatac caagaagact tgacttacaa gtttaaggtc ttggaaaagg atatccagac
    22801 tagactagct gtgataaaag aaatgcaggg aactgaagat aagtaaaaag agccccccgg
    22861 ctctttttta aaacgtaaac aagttatagt gaattgaatt tagaatagca caccatagtt
    22921 tctaaagcat tgttagagat tactttaaaa tcctcttatc aatttgttca tattctattc
    22981 aatttgttca tattctattt caatctatta tatatatccc atcaactatg catcataatt
    23041 taggtaactc atactcaata aaaatcaaaa agcaaactag aaagctaggc acagactgct
    23101 caaaacaccg tttt
//
LOCUS       DBEJNA010000034        22601 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEJNA010000034 DBEJNA010000000
VERSION     DBEJNA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.34"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            187..1950
                     /gene="aspS"
                     /locus_tag="ACL3JB_001589"
     CDS             187..1950
                     /gene="aspS"
                     /locus_tag="ACL3JB_001589"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0686291.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            1928..2869
                     /locus_tag="ACL3JB_001590"
     CDS             1928..2869
                     /locus_tag="ACL3JB_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0686292.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2873..3019)
                     /locus_tag="ACL3JB_001591"
     CDS             complement(2873..3019)
                     /locus_tag="ACL3JB_001591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686293.1"
                     /translation="MKIKVQTRKLAAGCSKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FEEY"
     gene            complement(3161..4147)
                     /locus_tag="ACL3JB_001592"
     CDS             complement(3161..4147)
                     /locus_tag="ACL3JB_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0686294.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4157..4957)
                     /locus_tag="ACL3JB_001593"
     CDS             complement(4157..4957)
                     /locus_tag="ACL3JB_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0686295.1"
                     /translation="MLPYPFSFFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTVSQASSIVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5210..6052)
                     /locus_tag="ACL3JB_001594"
     CDS             complement(5210..6052)
                     /locus_tag="ACL3JB_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0686296.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6054..7346)
                     /locus_tag="ACL3JB_001595"
     CDS             complement(6054..7346)
                     /locus_tag="ACL3JB_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0686297.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7457..8728)
                     /locus_tag="ACL3JB_001596"
     CDS             complement(7457..8728)
                     /locus_tag="ACL3JB_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0686298.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9263..10795
                     /gene="malQ"
                     /locus_tag="ACL3JB_001597"
                     /pseudo
     CDS             9263..10795
                     /gene="malQ"
                     /locus_tag="ACL3JB_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            10821..13079
                     /gene="glgP"
                     /locus_tag="ACL3JB_001598"
     CDS             10821..13079
                     /gene="glgP"
                     /locus_tag="ACL3JB_001598"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR0686299.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14124..14696)
                     /locus_tag="ACL3JB_001599"
     CDS             complement(14124..14696)
                     /locus_tag="ACL3JB_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686300.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHVAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            14773..14979
                     /locus_tag="ACL3JB_001600"
     CDS             14773..14979
                     /locus_tag="ACL3JB_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686301.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(15318..16166)
                     /locus_tag="ACL3JB_001601"
     CDS             complement(15318..16166)
                     /locus_tag="ACL3JB_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0686302.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16318..16596
                     /locus_tag="ACL3JB_001602"
     CDS             16318..16596
                     /locus_tag="ACL3JB_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0686303.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16598..18661
                     /locus_tag="ACL3JB_001603"
     CDS             16598..18661
                     /locus_tag="ACL3JB_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0686304.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18739..19995)
                     /gene="tyrS"
                     /locus_tag="ACL3JB_001604"
     CDS             complement(18739..19995)
                     /gene="tyrS"
                     /locus_tag="ACL3JB_001604"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0686305.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20137..>22601
                     /gene="pbp1b"
                     /locus_tag="ACL3JB_001605"
     CDS             20137..>22601
                     /gene="pbp1b"
                     /locus_tag="ACL3JB_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0686306.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVSPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
BASE COUNT         6717 a         4143 c         4937 g         6804 t
ORIGIN      
        1 gagtcagtaa ccatacctac ggtaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtattagcg ctaattttta gggctttcac ctgactttta aagactggca aacttttctg
      121 atgattttca tgaagagcct gcgcttttat ggtaaaatag taacagaata aaagaggaga
      181 gaaataatga aacgtagtat gtatgctggt cgtgttcgtg aggaacacat cggacaagaa
      241 ataaccttga aaggatgggt tggccgtcgt cgtgaccttg gtggtttgat ctttatcgat
      301 cttcgtgacc gtgaaggaat catgcagttg gttatcaacc ctgaaaaagt atctgcagag
      361 gttatggcaa cagctgaaag ccttcgtagc gaatttgtta ttgaggtgac tggtcaggtc
      421 gctgcgcgtg agcaagccaa tgataagttg ccaactggtg cggttgagtt aaacgtgaca
      481 gctcttattg tgcttaacac agctaagaca acaccatttg agattaagga tggcattgag
      541 gcaaatgacg atacacgttt gcgttaccgt taccttgacc ttcgtcgtcc agaaatgttg
      601 gaaaatctta aacttcgtgc caaggtgacc cactctatcc gcaactactt ggatgagttg
      661 gagtttatcg acgtggagac accattcctt tctaagtcaa cgcctgaagg ggcgcgtgat
      721 tatttagtgc cgtctcgtgt taataagggg catttttacg ctcttcctca aagtccacaa
      781 atcacgaaac agctcttgat gaatgctggt tttgaccgtt actaccaaat cgttaaatgt
      841 ttccgtgacg aagacttgcg tggagaccgc cagcctgaat ttactcaggt cgacttggaa
      901 acgtccttcc ttactgagca agaaatccaa gatattacag aaggcttgat cgcgcgcgtg
      961 atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc ctcgtgtgaa atacgatgat
     1021 gctatggctc tttacggttc tgacaagcca gatactcgtt ttgacatgtt gcttcaggac
     1081 ttgacagaag tggtcaaagg tgtagacttt aaagtctttt cagaagcacc tgctgtaaaa
     1141 gcgattgtgg tcaaaggagc tgcggacaac tattcacgta aagacatcga caagatgacg
     1201 gaagtagcca aacagtatgg tgccaaaggt cttgcttggg tcaaggtggt tgatggagaa
     1261 ttaaacggac cagttgccaa gttcttgact ggtatccaag aagaattgac aacagcgctt
     1321 gctcttgaag ataaggactt ggttctcttt gtggcggata cgcttgaagt ggctaatgca
     1381 acactgggtg cccttcgtgg acgtattgct aaagagcttg gcttgattga taatgataag
     1441 ttcaacttcc tttgggtggt tgactggccg atgtttgaat ggtctgaaga agaaggccgc
     1501 tacatgagcg cccaccatcc tttcaccctt ccacaggaag agactgctca cgaattagaa
     1561 ggtgatttgg ctaaggttcg tgccattgct tacgatatcg tcttgaacgg ttatgagctt
     1621 ggtggtggta gccttcgtat caaccaaaaa gaccttcaag aacgcatgtt caaggctctt
     1681 ggtttctcag ctgaagaagc caatgaccag tttggtttcc ttcttgaagc catggactat
     1741 ggtttcccac cacacggtgg tttggctatc gggcttgacc gttttgtcat gttgcttgct
     1801 ggagaagaaa atatccgtga agtcattgcc tttcctaaga acaacaaggc aactgaccca
     1861 atgacacaag ctccatcaac agtcgctctc aaacaactag aggaactcag cttacaagta
     1921 gaagaagatg aaacaagcaa aacgaattaa gcggtggcgc tattatctgc gccgctttgc
     1981 ttatcagata aaaattttac gtgtcttaca aagtatctct cgagaaaagt atgatgagaa
     2041 gatttcggcc tctctggtct atggtttttt atcagcagta gcagttaatt tctttttcca
     2101 accagggcat gtgtattcga gtggtgcaac aggtctggca cagattatct ctgccttgag
     2161 taatcactgg tttggttttc atattccgat ttcgctaagc ttctacgcca ttaacttccc
     2221 tttgatggtc ttagcttggt atcagattgg ccataagttc accgtcttta cctttatcac
     2281 ggtatctatg agttccttct ttatccagtt tgtccctgtg gcaaccttga cggaggatcc
     2341 cattatcaat tccctttttg ggggtgttgt tatgggtttg gggattggtt ttgctcttcg
     2401 aaacaatatc tccagtggtg ggacggatat cgtcagcctg actattcgta agaaaacggg
     2461 taagaatgtc ggtagtattt ctttcttggt aaatggaact atcatgctga tagcaggttt
     2521 gacctttggt tggaaatacg ctctttattc tatgattacc atctttgtct ctagccgtgt
     2581 gacagacgca gtctttacta agcaaaagcg tatgcaggcc atgattgtga caaatcatcc
     2641 agagaaggta attgaaaaaa tccataaaaa attgcaccgc ggagcaacca tgatccacga
     2701 tgcagaagga acctataatc acgagagaaa ggcagtttta atcactgtca ttacacgtgc
     2761 agagtttaat gaatttaaac agattatgac acaagtggat ccaagctcct ttgtctctgt
     2821 ctcggaaaat gttcatattc taggaagatt tgttgagata gataattagt gattaatact
     2881 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatgg ttactgactt
     2941 cgtcagtttc atctacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag
     3001 tttgcacttt gattttcatt gagtataaaa agatcttgga aaaagactca atttcagtag
     3061 aaaaggaagt aaatcttccc acattaaaac gcatagtatc aagttttttc aatacctgat
     3121 actatgcgtt tttgctttta acgacttttt gcccagtctc ttatttttcg ataattttgt
     3181 gggcgatcaa ttgacggtaa caaatttgtt tattgttttt attatcatta ataatctgga
     3241 gaatagtttc aagggaaaca cgaccaagct ctaaactatt gatatcgaca taggctgcca
     3301 agttgagctt gggattaacc gagtcaaagc tgagaacagg gacatccagc tggtgtttgg
     3361 caatatagtt acaaacacct tcagctagga ggctatcggt tgtgatgata gcatcaattt
     3421 gtggatcgtg cttgaataat cgcttgctaa atttatagcc cttttcttcc agaaactcgt
     3481 cggcaaagta gatgcgattg ttgtcagtgg taagtttgta atgtttaagc gcctgttcat
     3541 agcctgttaa acggtctttg gtcacgaaga gctttttact tcctccgata aaggcaatgc
     3601 gtttgcagcc ttttttgatg aaatattcag tcgcatcaaa accagcttga acattgtcgt
     3661 tgtcgacaag tgggatgaaa ggagatagag atttacctag gataaggaag gggaactgtt
     3721 cttctgcgac gagttttacg agagggtctt cttcttgggc atagagaaag attagcccat
     3781 ctacacgctt gccgtagacc atttgtgaaa tagcgttgag acgctccttc tcatctttcc
     3841 ctgttgctat ctgaatggca tagtggtttt cagatgcgac ttgagagatg ccacgtagaa
     3901 ccgatggaaa gaaaggattc tggtagaagg cgtctgagtc atcaggaaga actaatccga
     3961 taacctgagt atagctgctt accaagctac gagcgttgag gtttgggtgg tagttgagtt
     4021 ccttcatagc tttgcgaacg cgtttttttg tttcgtcgct aatggttgat ttattttgaa
     4081 taacacgggt tacggttgaa ggcgaaacac cagcagcctt ggccacgtct ttaatcgtaa
     4141 cgggcataaa aatctcctat ttatggtaat ttggatcacg gaaatgtgtt ttataaaaga
     4201 tagtgaccag atacagaaca aaaagaatat tttgtacagt aatcagggtt gtcatatttt
     4261 ggccaaataa tcccaaaata agtgtaatca gagtcggcaa tcctaaacag ttcaagataa
     4321 agtgatagca ctctttaaag gttctaaatg aaaagaggcg tgatttctta gtgatataaa
     4381 ggagaagact agctcctaga gagacgataa agaaattcaa accaaagagg aagctcgcac
     4441 cgagaactag gaagaggctg atatagacac gattttgttg gtaccagtct ttagaaattg
     4501 cttgggtcaa gctgtctttg cttttgaaac tctcagtctg aatggctcgg taagagatgc
     4561 gggtcagttc cttgctttcc ttgctgatga ctagctcatt tgtatcgaaa tgcagttgca
     4621 agtccttagg taattccttg atttgacttg gaccaatcac aatagaagag gcttgactaa
     4681 ctgttccagt ataagttaat gtgccatcga caattgtagc atgttcagag agatcctgga
     4741 caaccttatc tgtcagaggt tcatagacat tatcgataaa agtttctagc ggataggtct
     4801 cctgggagct gttttggata gcaatgggta ccatagacaa gctgataagg aagatactgg
     4861 taaagagaag ttgaaaccag ttgagctcga aacgtttgga caggggctta cgaaaccccc
     4921 aaatacttga aaaaaaggaa aatggatatg gaagcatagg tatctttcta aaaggtgttt
     4981 tctatataag tattattata tagagaaatg cgctttattt caagtctagg agaaaaattg
     5041 cttgctacaa ggatattatt tacagtgaca attgctaata atcaatgaaa atcaaagtgc
     5101 aaactagcca caggttgctc aaagcacaac tttgaggttg gagataaagc tgacgtggtt
     5161 tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc ggggataaat tatcccttgt
     5221 cgccaccact tgtaagtcct gaaacaaagt tcttttgtag gaagaagaag agaatacaga
     5281 ttggaagggc gatgaggata gcacctgctg agaagtaggc aatcttcaag tttttcgcat
     5341 tgttaacgaa ggtttggaga cctacggcaa cagtaaagta ttctttctca cgaagcaaga
     5401 aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa
     5461 ccattgggcg aacaagtggt agaacaattt gccagaagcg gcggaagtgt cctgcaccgt
     5521 ctagttttgc agattcgtct aaagacattg gcactgtatc gaagtagcct ttcatgagcc
     5581 aagcattcat cgggatacca ccaccaacgt agaggaagat gaggaaccag ttgtggttaa
     5641 gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa agcggccata gttggcacca
     5701 tttggatgat caagaagaag accaaacttt gtttacgagc caagaagttg taacggctgt
     5761 aagcataacc agcaagtacg atgatacttg tttgaacagc catggtaatt aaggcgataa
     5821 tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt gaagaggcct ttaaagttat
     5881 caaaattgag gtcgatatta gtatctagtt taaaggctga gacgttacct gctttaaagg
     5941 ctgacataat ggtaatcaac agtggataga taattacaat tgatagacca atcaggtaaa
     6001 ggtaagtaag gctttgagtc agtctacgtt tgagtttaat tgagttattc atcttagacg
     6061 tcctccatat caaatgcgtg tagtttcttg aatgcgatca tagagattga gatgacaatg
     6121 atagagataa tcaaggtaac agctgccgcc attgagtatt gaggagatgt acctgttgtc
     6181 aaacggtaga tccatgagat caagatatcg gttgaaccag ctccacctcc gacactacca
     6241 ggtcctccac cattgaagag gtacatgata gagaagttgt taaagttgaa ggtgtattgg
     6301 ctaatcaaag taggtgccgc aacagccaaa atcattggga aagtgatgtt gcggaatttt
     6361 tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa ggtcgttagg aatagattgc
     6421 aagataccca aagtcaaaac gtagatgtat gggaatccga gccaaccttg catcataatc
     6481 aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa
     6541 ggaaggaatt tagccaagat tggcaatact tgagtgttga tagcaccgac actatcgtta
     6601 aacatgtttg agaatgtcaa gatagtgatg aaggctggga cagcccaagg aagaaggaaa
     6661 ataacaccaa agatacgttt tcctttgata aatggttggt tggcaatgat agctgtgaag
     6721 ataccaatta cgatttgtaa agtagaagct gccaaagccc aaatgatagt ccaagaaaga
     6781 acagaaccaa aggcagaacg gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa
     6841 ccaacccagt ccaacaactt gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg
     6901 atcatcaagg ttacgataac tgggaagata atcgcgaagg tcatggcaac ataagatgga
     6961 atgatcaaga ggtaagggaa gccattttca taaatccctt tgatcatgtc tttgagtgtg
     7021 cgtggaactg gaattccatt gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt
     7081 gagaaataaa agagtacata aacgattaca aagattagat ggaaggcacc acgaatcagc
     7141 ataaagaggg aattatcacg acctggtttg tcaccaagag tgatgaggtt gctcaattca
     7201 ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg ttacaccaag gaagataaaa
     7261 cctttggctt tttgtttatt gtaaatctgt cctaacccag gaatgataga cagcagggct
     7321 gctttactag gttgttgctt ttccatatta actcctttca taggatacta cttttttata
     7381 agaaagctaa attatttgtg tctctattga taaattcaaa gggggatttg atttccaccc
     7441 cccttgaaca aattttttat tcaccaaatt tttgtttgat tgtttctttg atcaatgtta
     7501 cagcatcgtt agcagctgtt ttagcatctt tttgaccact tacagcatca aagagcatat
     7561 ttttcgctgg atcccaaact gcagacattt gagagatgtt tggcagtggt tgagtgttct
     7621 tgaactgttt gataacagct gttgtcaact catcgttttt accttcagcg tatgaacgag
     7681 cctcagtatt agctgggatt tcgttagtct tatcatataa tactttttgt tgttcagttg
     7741 caacaaggaa gtctacaaat ttttgagaag cttcaaggtt cttaacggct tgaggaatga
     7801 cccaagcttt accaccaccg aatgcagcat attcttttcc atttggaaga gttgggatag
     7861 ttgcaactcc gtagtttact ttagcatctt taaaggcttg agctttccaa ggtccgtcga
     7921 tgatagcagc tgttttacct tcttggaatt gagtttggat taagtttcca gcaccttctg
     7981 tatcttgcat acctttaggc catttttcgt accaagattt agcgtagttg atacctgcga
     8041 tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt
     8101 aagcaccgtt accggcaaga agtccatatg tatagtagaa gtttgtccag tcagctagga
     8161 aggcagtagt tttaccatct tcaccagcga atgcgtattt gctatcttta gcaaggtttt
     8221 ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc tttgttgtag tacataacaa
     8281 gtgactcgat aacggcagga gcaccgtaaa ctttaccatt agcagctgtt acaagagatt
     8341 tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag
     8401 aaccaaggct acctacacgg tcgtatggag ccatcataac atcagggaca ttaccagatt
     8461 ggttgtcaag agaaagttta tcaagacctc ctagagcatc accagtttta agagtgactt
     8521 ttactccagc ttctttttca taagctttag caacctcttc aatatagctc ttatatccct
     8581 cgtctacata tacagtgagt tctttgactt cagatgaacc agaatcagca ggcttatcag
     8641 cagttttgct tccgcaagct accaaaagca agctagcaag tgtaacagtt ccaagcaccg
     8701 cagtgctctt cataaattta gatgacatag tgtattcctc ccaaagaata gcaagtttta
     8761 ttgataagga aacgcaaacg ttttccttta tgagcttagt atagcacaaa tagaaaacgg
     8821 ttgcaagtat tttttgtaaa aattttaaaa aatttttaag cttgatttga tagcataatt
     8881 ttgcatttta atagaagaaa agtatgaaat agataagaat acagtatttt taataaaaat
     8941 atatggaatc tgtctaaaga gggaaaccag gaggggctac ctccctgttt ctaatcccta
     9001 tctattttct atagacgttt gtgctttgtt gcatataaat tcaagctccc taaggaggtt
     9061 ttgtactttg tagactgtct cgtgagagtc aaactttagg attagatagt tttaagttat
     9121 ctttgctaaa atgagttagt ctccttaaaa ataatcaaaa aagtttttta aaaacgcttg
     9181 caattatgct tgaaaaggag tatacttata agtaacgcaa acgtttgcgt ctgcaaaata
     9241 cgcaacgttc cattatttta acacacgagg tgctattatg aaaaaacgtc aaagtggtgt
     9301 gttgatgcac atctcttctc ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc
     9361 ttacgacttc gttgatttct tggtccgtac aaaacaacgt tactggcaaa tccttccatt
     9421 aggagcaact agttacgggg attctcctta ccaatctttc tcagccttcg caggaaacac
     9481 tcattttatc gatttagata tcttggtgga gcaaggtttg ttgggagcga gtgaccttga
     9541 aggagttgac tttggtagcg atgcgtctga agttgactat gctaaaatct actatgcacg
     9601 tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa gtcggagatg ttaaagattt
     9661 tgagaaattt gctcaagaca accaatcatg gcttgagctc tttgctgagt atatggctat
     9721 caaagagcat tttgacaatc ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg
     9781 taaagcttca gcacttgaaa gctatcgtga gcaattggca gacaagttgg tttaccaccg
     9841 tgtgactcaa tacttcttct tccaacaatg gttgaaattg aaagcttacg ctaacgacaa
     9901 ccacattgaa atcgttgggg acatgccaat ctacgtagcg gaagattcaa gtgatatgtg
     9961 ggcaaatcca catctcttca aaacagatgt caatggtaag gctacttgta tcgcaggatg
    10021 cccaccagat gagttttctg taactggtca gctttggggt aacccaatct atgactggga
    10081 agcaatggac aaagacggct acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat
    10141 ctacgatatc gttcgtatcg accacttccg tggcttcgaa tcttattggg aaatccctgc
    10201 tggttccgat acagcagcac ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc
    10261 agccgttaag gaagaacttg gtgagctaaa catcatcgca gaagaccttg gcttcatgac
    10321 agatgaagtg atcgaattac gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt
    10381 tgccttcaac ccagaagacg aaagcattga tagcccacac ttggcacctg ctaactcagt
    10441 tatgtacaca ggaacacacg ataacaatac ggttcttggt tggtaccgta atgagattga
    10501 tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt aaagaatacg aaacagtggt
    10561 acacgctatg cttcgtacag tattttcatc agttagcttt atggcaattg caactatgca
    10621 agatttacta gaattggatg aggcagctcg tatgaacttc ccatctaccc ttggtggaaa
    10681 ctggtcttgg cgtatgactg aagatcaatt gacaccagct gtcgaggaag gtttgcttga
    10741 cttgacaaca atttatcgcc gaattaatga aaatttggta gatttaaaga aataagacaa
    10801 taatcaggag acaactaaac atgttatcac tacaagaatt tgtacaaaat cgttacaata
    10861 aaaccattgc agaatgtagc aatgaagagc tttaccttgc tcttcttaac tacagcaagc
    10921 ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa agtttactac atctcagctg
    10981 agttcttgat tggtaaactc ttgtcaaaca acttgattaa ccttggtctt tacgacgatg
    11041 ttaaaaaaga acttgcagct gcaggtaaag acttgatcga agttgaagaa gttgaattgg
    11101 aaccatctct tggtaatggt ggtttgggac gtttggctgc ctgctttatc gactcaattg
    11161 ctactcttgg tttgaatggt gacggtgttg gtcttaacta ccactttggt cttttccaac
    11221 aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc atggttgaca gagcaaaact
    11281 ggttggttcg ctcaagccgt agctaccaag taccatttgc agactttact ttgacatcaa
    11341 ctctttacga tattgatgtt actggttatg aaacagcgac taaaaaccgc ttgcgtttgt
    11401 ttgacttgga ttcagttgat tcttctatta ttaaagatgg tatcaacttt gacaagacag
    11461 atatcgctcg caacttgact ctcttccttt acccagatga tagtgaccgt caaggtgaat
    11521 tgctccgtat ctttcaacaa tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg
    11581 aagcaatcga aaaaggaagc aacttgcatg accttgctga ctacgcagtt gtccaaatca
    11641 acgatactca cccatcaatg gtgattcctg aattgattcg tcttttgact gcacgtggta
    11701 tcgagcttga cgaagcaatc tcaattgttc gtagcatgac tgcctacact aaccacacaa
    11761 tccttgctga ggcgcttgaa aaatggcctc ttgaattctt gcaagaagtg gttcctcact
    11821 tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg
    11881 ttcaaatcat cgatgagagt ggacgtgttc acatggctca catggatatc cactacggat
    11941 acagtgttaa cggggttgca gcacttcata ctgaaatctt gaaaaattct gagttgaaag
    12001 ccttctacga cctttaccca gaaaagttca acaacaaaac aaacggtatc actttccgtc
    12061 gttggcttat gcatgctaac ccaagattgt ctcactactt ggatgagatt cttggagatg
    12121 gttggcacca tgaagcagat gagcttgaaa aacttttgtc ttatgaagac aaagcagctg
    12181 tcaaagaaaa attggaaagc atcaaggctc acaacaaacg taaattggct cgtcacttga
    12241 aagaacacca aggtgtggaa atcaatccaa attctatctt tgatatccaa atcaaacgtc
    12301 ttcacgagta caaacgccaa caaatgaacg ctttgtacgt gatccacaaa taccttgaca
    12361 tcaaagctgg taacatccct gctcgtccaa tcacaatctt ctttggtggt aaagcagctc
    12421 cagcctacac aatcgctcaa gacattatcc atttaatcct ttgcatgtca gaagttattg
    12481 ctaacgatcc agcagtagct ccacacttgc aagtagttat ggttgaaaac tacaacgtta
    12541 ctgcagcaag tttccttatc ccagcatgtg atatctcaga acaaatctca cttgcttcta
    12601 aagaagcttc aggtactggt aacatgaaat tcatgttgaa cggagctttg acacttggta
    12661 ctatggacgg tgctaacgtg gaaatcgctg agttggttgg agaagaaaac atctacatct
    12721 tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa agcagcttac aaatcaagcg
    12781 aattctacgc tcgtgaagct atcaaaccat tggttgactt catcgttagt gatgcagttc
    12841 ttgcagctgg aaacaaagag cgcttggaac gtctttacaa tgaattgatc aacaaagact
    12901 ggttcatgac tcttcttgat ttggaagact acatcaaagt caaagagcaa atgcttgctg
    12961 actacgaaga ccgtgacgca tggttggata aagtcatcgt taacatttct aaagcaggat
    13021 tcttctcatc tgaccgtaca atcgctcagt ataatgaaga catctggcac ttgaactaat
    13081 actcttcgaa aatctcttca aaccacgtca gctttatctg caacctcaaa gcggtgcttt
    13141 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taagatacaa
    13201 atttatacta atacatcttg taaaaaagcg agtttcgatt gaaattcgct tttttaaatg
    13261 ctgtggattt gggtcaatct tgtctaaaaa tagggaaatc ctagatacag tgaaggcttt
    13321 aaatgctggt ttttactgtc ttcagcctta tattttttcg tagttggtta tctcatatct
    13381 cttgtattcg cttacataaa gtattataat ataattgtag gaaagaaggt gtttttatga
    13441 tatacacact taaattggtg ttgtttatta cctttcttgt aataagcttg ttacctgata
    13501 agatttttgg aaaaaataaa aaaatttgga aaatagtttt tgcaatattg acggcagtgg
    13561 cagcattgtc atttatgtac taagttattt taagaatgta gggaaataaa ccctacattc
    13621 tttttagttt tttctgtttt ctaaattcta tttatccaag cgattcaaca tttcttgctt
    13681 cttcgcttca agttctgcac gcttttcttc gatttcggca tgttttttct cgagttcaga
    13741 acaacttgca ccattgctaa attcttttcg ccatcaggag atagggtgag tcgacatgtc
    13801 tattactcac ccaaagcagt cctacaaagc aggaattttc tgttactttt ttggaaatag
    13861 taacgtttat acagctttga cacttcgtat caaagcgcca aacacactcc gagggattta
    13921 cagaaagcag aaaaggaatg atctggtata agatcattcc ttttctctct ttttctttaa
    13981 gtaattatat acaatgtacg acgaagtcgt cattgcaatg ctgatccacc acctaaaggg
    14041 aactttaaac aacattgata agataaagaa tataaacaac gaaaatacgt tatacccaat
    14101 taattttatt gtatatctca tgattaaaag ttaatccttc cgttgttagg aatggcatca
    14161 tttttatccc ataattgtgc taaataagtc cccggtgata ataaattcat agcgaattct
    14221 aaagcaacat catttacaaa ccaactacct agatatctag aaattgctga acgaatagca
    14281 ctttttgcta catgttttcc ttttacttta attagatttg cgaggcctgc agtagttcct
    14341 cctaatgcta aagctattgc agtatctaat agagcaccca tttgattaac tgtaatacct
    14401 tgccaagctg ctctaaatgg agagtatgta ggtgggattg tataatcgcc ttgtaattgt
    14461 cggttaatta cttctttgat ccattgttgt gagacgtctg gatgaaaaga ttggatttcg
    14521 tttgcaagtg tattgatttg ttcttctgtt agagaagtga caggttgaag ttccatattt
    14581 gtttcaattt gtgatacttg ttcagaagcg tatacagctg aaacacttgg aatcgctgat
    14641 acaattaaca caattgacgt caaaaaaacc gaaataaatt tcattaattt gttcatgagc
    14701 ttttctcctt tttatttgta tctgcttaca ttttatcata tactgttatt atagtcaaaa
    14761 aaatatgcta ttatgttaaa aaaatatttt tcaaaatata aatggacgga tttattttgg
    14821 attttatttg ttattttgac ctgcctctat attggtaacc atgatttgtt tactctcaat
    14881 catcaagaat tctcttttcg tggtagcgtt tggggtctgg tactggcctt atatcactta
    14941 ttgttcattg ataagtttgt aatttcgaat cgaaaataaa gattagaact atgattgact
    15001 ggctactttt aatattgatt ttggaggaag attttgtctc tattatttat tattttaaat
    15061 ttatttattt tgtataagat ctattctttg aggcgggaaa aatcgaaata cttgatttat
    15121 acggcctata tcatatttgg ggtaaatgta gtatatggta ttcaatggtt attaagagaa
    15181 ctgatttcaa ctatttcccc ttaatgtgta tggaaactat aacaaaacgc ataagattaa
    15241 ggtttgtgta cctgttctta tgcgttttta taatattgaa gattttcggt aagttttata
    15301 cctttgggaa gtctagttta gaatgctttc ccaaccaaaa tctctgcttc gatggtaatc
    15361 tctgtcagtt ggctccagtc aatcttgctc tggtcaacgt gaaagaggag aggagtcata
    15421 ctgagtaggg cttggagttg ttctgctgtg atagtcttag tcagagaggc agtttgacta
    15481 gataggatgg taaagtgttc ctggaaatgc tccttgatat cttggttaga atactccttg
    15541 tttgtcagct ggtcctgtac tctttgacgg atttctttga ggtgattttc agttgggata
    15601 acctttatca agataccgtc tttggataaa acgcgacgaa attctccata gttggcaggt
    15661 gagaagatat caagcagaat atccatgtta gcgtctttta taggaagtcg tgccaagtcg
    15721 ccaacgaacc aattgactgc ccagttgggt tcacttttag cagcgatttg gactgaatct
    15781 ttggagatgt caaaggcata gaaagttttt tcagagtgac tttcttgtag tttgcgagaa
    15841 tagaatcctt caccacaacc gatatccaaa attgttgtgg tagtttttga gcttgcaagc
    15901 aagtcagata cagcatctaa gatagcttgg taaaagccgg cttctaggat ttgttgacgg
    15961 ttttgaaaat tttccttgtc atagttagca gattgcttga tttgaggtgc tagattgaca
    16021 tagccaaatt tcgccaagtc aaaagaatga cggttgcagc acttgaaatt agtctctaac
    16081 agagtcagat tttcttgaca gataggacag gcaaaggcag tcgcagaagc aaaacgctga
    16141 agtttgggct tgagatttgt attcatagtt taagtgtatc aaaagaggca aatgaaagca
    16201 actttaggaa taagtagatg ggagattcag tagaaataaa actaattctc caatttatag
    16261 aatgaaattg cttttatatc taaattgcta tataataatg ataaggagga aataagtatg
    16321 ttaaaagaag tattaaccgt tgcaaaagtt gcgaaaaaat cttcattatt tttgggtggt
    16381 gtcgcatttg gtacccttgg tttgaaaatc ttagcaagta aggaagctaa aaaaggttat
    16441 tctaaagctt tggctaaggc ttacaagttg aaagacgagc tagatgcatc tgtttctgtt
    16501 gtgaagcaac atggagacga tgtcttgcaa gatgccaaat atttgtacga gcaagagaaa
    16561 aaagaagagc aattagatag ccttataggt gaataatatg tcttttaaag tgctacatag
    16621 aggataccaa catatccgac tatcatcttc tttttcactt accttggata ttcaagacta
    16681 tcttcgttcc ttggcgagag atgaaaaggg gattgagtct atccagtttt acatggatca
    16741 acagcacttt actctacgca taaaagaagg cttttctgta ttagataatg cagaagcctt
    16801 tttaaaaaga attgataaag ggaaagtttc tgagttgatg actcttccca ttcgtagaga
    16861 agagagtgct tattctattg tttcaggtgc agcggttaag cgtgtacttt ttcgtagttt
    16921 tgtgccgtat cctattcgct atatatggac ttgttatcag gctttgggtt atattagaga
    16981 agcctatcaa acactagcgc gtaaggaact aacgatggaa gtcttggact gttcggctat
    17041 tttattgtct ttgtttatga accaatccaa gacagctagc aatatcatgt ttatgcttga
    17101 tttggggaat catttagatc agtggtcctt gaaaaaaact gcaacagatt tagaacagag
    17161 tcttcttgca aaagagagcg atgtattcct agtacagggc gatacggttg ttagtatcaa
    17221 gagttccgat gttcaaatag gagatgtctt gatcttatct caaggaaatg aaattctgtt
    17281 tgatggacaa gtagtttcag gtttaggtat ggtcaacgaa agttccttga caggagagag
    17341 ttttccagtt gaaaaaagag agtctgattt ggtttgtgca aatacagtat tagaaactgg
    17401 agagttacgc attcgtgtaa cagataatca gatgaacagc cgtattttac agctgattga
    17461 gttgatgaag aaatctgaag aaaacaagaa aacgaaacaa cgctatttca tcaagatggc
    17521 ggataaagtc gtcaaatata atttcttggg ggctggactg acttacctat tgacaggttc
    17581 tttttctaag gctatttctt tcctattggt cgatttctcc tgcgctttga aaatctctac
    17641 tcctgtagct tatttgacag ttatcaagga agggttgaac cgtgaaatgg tgattaagga
    17701 tggagatgtt ctggagaaat atctggaagt tgatactttc ttgtttgata agacaggaac
    17761 aatcacaact agttatccta tagttgaaaa ggtgttacct tttggagact atagtgagga
    17821 agatattctc agaatcagtg cctgtcttga ggaacacatt tatcatccta ttgctaatgc
    17881 catcgtcaag caagctgaga tagagggaat tgaacatgag gaaatgcatg ggaaactcca
    17941 atatatcgca agcaagggga tcaaatctca tatagatggc caaccagttc ttattgggaa
    18001 ttatgtcttg atgcaggatg agcagattca tatcagttca gaacaaaatg ctttaattga
    18061 agagtacaag agtcactaca atctcttatt cttggcttat caaaatgaat tgattggaat
    18121 gttctgcatt catactcctt tgagaaaaga agcaaaaaca gccttggata aacttaaggc
    18181 acaggggaaa aaattgattc tggcaacagg ggacaccttg gttaggacag aggaattagt
    18241 caaagatttg ccctttgatc aggtctatac agacttgaaa cctgatggga aatttgagtt
    18301 agtagagaaa ctgcagaaag caggtcacac tattttgatg gttggagatg gattgaatga
    18361 ctcagcggct ctaactctat cagatatcgg tgtggtgatg aatgagagtg cagatatttc
    18421 taagcagatg agtgatatct tattgttaga taatcgtttg gatttcttcc aagagttgga
    18481 ttcgttatca tcatctttgc aaacactcat caagaaaaat attcaagata ccgttgtcgt
    18541 aaatagtagt ttgattggct tcggcttatt taattggctc agtccttcaa atctctctat
    18601 cttacataat ctaacaacct tgcgcattgt cctgcgtagc ctgtctatta aaaatagata
    18661 gatgagagtt attaacagca aaaaggagtt acctttctcg aggttaactc ctttgtttat
    18721 agataaatgt tgaatagttt agtaagtcaa tacaaagtat tttttcttcc cacgacggat
    18781 aacagtcagt tcattttcta acttatcagc gtcactcaag acatagtcaa ggtcttggat
    18841 gcggtcgccg tttacgtaga tggctccgtt ttggacgtct tcacgggctt ggcgttttga
    18901 gttaactata ccagatgaga cgagcagttc cacgatattg ttatgttcgt ctgcctgtac
    18961 ttggtagttt ggcacaccac gaagtccttg tttgagctct ttgacagaaa ggtttttgat
    19021 gtttcctgca aagagttgct cagtgatgtt aagtgcttct ttgtaggctt cttctccgtg
    19081 aacaagtgta acaacttcac gagccaagac tttttgagcc aagcgttcgt gtggcgctgc
    19141 ttcaaattgt ttacgaatat cttcaatctc atcaagtgac aagaaagtaa agattttcaa
    19201 gaagcgaaca gcgtcagcgt ccatcacgtt catccagaat tggtacattt cgtatggaga
    19261 agtcttttcg ggattgagcc atacggcatt tccttctgat ttaccaaatt tcttaccagt
    19321 tgcatctgtg attagtggaa cagtgataac gtgaccagtc ttgtccgcct tacgacgaag
    19381 caattcggta ccagctgtca tatttcccca ctggtcagaa ccaccgattt gaagagtgac
    19441 attatggtct tggttaagga cgaagaagtc gtacccttgc atgatttggt aagcgaactc
    19501 agtgtaagaa attcctgttt cgatccgttt tttaacagat tccttactca tcatgtagtt
    19561 gaccgtgaag tattttccaa tatcacggag gaagtcaatg aagctgatgc tgccaaacca
    19621 gtcgtagttg ttgaccatga cagccttgtt ttcgccattt tcaaagtcaa gaaaacgaga
    19681 aagttgtcct tggatagact tgacccagcc atctactgtg tcttttgttt ggagactacg
    19741 ttcagcatct ttgaaggacg gatctccgat gagacctgta gcaccgccaa cgagcgcata
    19801 aggtttgtga cctgctagtt gcaagcgacg acttgtcaag attgcgacaa ggtggcctag
    19861 gtgaaggctg tcagcagttg gatcgtagcc agtataataa gaaacttgac cttcttctag
    19921 ggctttacgc aaagcttctt catcagtcgt ttgaaatatc aaaccacgct cttttagctc
    19981 atcaaaaatg tgcatgtgtc ttttctcctt tttaaaatta ttgtttctac ctattgtatc
    20041 acaaacttgg gcaatagcct agcagaatag ggaagaaagt ggctatttta ttgaaaattt
    20101 cccttttgtg gtataataga tagagtgagg aaatccatgc aaaatcaatt aaatgaatta
    20161 aaacgaaaaa tgctggaatt tttccagcaa aaacaaaaaa ataaaaaatc agctagacct
    20221 ggcaagaaag gttcaagtac caaaaaatct aaaaccttag ataagtcagc cattttccca
    20281 gctattttac tgagtataaa agccttattt aacttactct ttgtactcgg ttttctagga
    20341 ggaatgttgg gagttgggat tgctttgggg tacggagtgg ccttatttga caaggttcgg
    20401 gtgcctcaga cagaagaatt ggtgaatcag gtcaaggaca tctcttctat ttcagagatt
    20461 acctattcgg acgggacggt gattgcttcc atagagagtg atttgttgcg cacttctatc
    20521 tcatctgagc aaatttcgga aaatctgaag aaggctatca ttgcgacaga agatgaacac
    20581 tttaaagaac ataagggtgt agtacccaag gcggtgattc gtgcgacctt ggggaaattt
    20641 gtaggtttgg gttcctctag tgggggttca accttgaccc agcaactaat taaacagcag
    20701 gtggttgggg atgcgccgac cttggctcgt aaggcggcag agattgtgga tgctcttgcc
    20761 ttggaacgcg ccatgaataa agatgagatt ttaacgacct atctcaatgt gtctcccttt
    20821 ggccgaaata ataagggaca gaatattgca ggggctcggc aagcagctga gggaattttc
    20881 ggtgtagatg ccagtcagtt gactgttcct caagcagcat ttttagcagg acttccacag
    20941 agtcccatta cttactctcc ttatgaaaat actggggagt tgaagagtga tgaagaccta
    21001 gaaattggct taagacgggc taaggcagtt ctttacagta tgtatcgtac aggtgcatta
    21061 agcaaagacg agtattctca gtacaaggat tatgacctta aacaggactt tttaccatcg
    21121 ggcacggtta caggaatttc acgagactat ttatacttta caactttggc agaagctcaa
    21181 gaacgtatgt atgactatct agctcagaga gacaatgtct ccgctaagga gttgaaaaat
    21241 gaggcaactc agaagtttta tcgagatttg gcagccaagg aaattgaaaa tggtggttat
    21301 aagattacta ctaccataga tcagaaaatt cattctgcca tgcaaagtgc ggttgctgat
    21361 tatggctatc ttttagacga tggaacaggt cgtgtagaag tagggaatgt cttgatggat
    21421 aaccaaacag gtgctattct aggctttgta ggtggtcgta attatcaaga aaatcaaaat
    21481 aatcatgcct ttgataccaa acgttcgcca gcttctacta ccaagccctt gctggcctac
    21541 ggtattgcta ttgaccaggg cttgatggga agtgaaacga ttctatctaa ctatccaaca
    21601 aactttgcta atggcaatcc gattatgtat gctaatagca agggaacagg aatgatgacc
    21661 ttgggagaag ctctgaacta ttcatggaat atccctgctt actggaccta tcgtatgctc
    21721 cgtgaaaagg gtgttgatgt caagggttat atggaaaaga tgggttacga gattcctgag
    21781 tacggtattg agagcttgcc aatgggtggt ggtattgaag tcacagttgc ccagcatacc
    21841 aatggctatc agaccttagc taataatgga gtttatcatc agaagcatgt gatttcaaag
    21901 attgaagcag cagatggtag agtggtgtat gagtatcagg ataaaccggt tcaagtctat
    21961 tcaaaagcta ctgcgacgat tatgcaggga ttgctacgag aagttctatc ctctcgtgtg
    22021 acaacaacct tcaagtctaa cctgacttct ttaaatccta ctctggctaa tgcagattgg
    22081 attgggaaga ctggtacaac caaccaagac gaaaatatgt ggctcatgct ttcgacacct
    22141 agattaaccc taggtggctg gattgggcat gatgataatc attcattgtc acgtagagca
    22201 ggttattcta ataactctaa ttacatggct catctggtaa atgcgattca gcaagcttcc
    22261 ccaagcattt gggggaacga gcgctttgct ttagatccta gtgtagtgaa atcggaagtc
    22321 ttgaaatcaa caggtcaaaa accagggaag gtttctgttg aaggaaaaga agtagaggtc
    22381 acaggttcga ctgttaccag ctattgggct aataagtcag gagcgccagc gacaagttat
    22441 cgctttgcta ttggcggaag tgatgcggat tatcagaatg cttggtctag tattgtgggg
    22501 agtctaccaa ctccatccag ctccagcagt tcaagtagta gttctagcga tagcagtaac
    22561 tcaagtacta cacgaccttc ttcttcaagg gcgagacgat a
//
LOCUS       DBEJNA010000035        22573 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEJNA010000035 DBEJNA010000000
VERSION     DBEJNA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.35"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            66..290
                     /locus_tag="ACL3JB_001606"
     CDS             66..290
                     /locus_tag="ACL3JB_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0686307.1"
                     /translation="MIAGGLIGLLAGKITKKSSSMGIIANVFAGLVGASAGQSLLGSW
                     GSSIAGMALLPSIVGAAIVITVVSFFTGRK"
     gene            374..940
                     /gene="amaP"
                     /locus_tag="ACL3JB_001607"
     CDS             374..940
                     /gene="amaP"
                     /locus_tag="ACL3JB_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0686308.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            952..1122
                     /locus_tag="ACL3JB_001608"
     CDS             952..1122
                     /locus_tag="ACL3JB_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0686309.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1161..1769
                     /locus_tag="ACL3JB_001609"
     CDS             1161..1769
                     /locus_tag="ACL3JB_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0686310.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1800..2003
                     /locus_tag="ACL3JB_001610"
     CDS             1800..2003
                     /locus_tag="ACL3JB_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0686311.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2098..2337)
                     /locus_tag="ACL3JB_001611"
     CDS             complement(2098..2337)
                     /locus_tag="ACL3JB_001611"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686312.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            2616..2861
                     /locus_tag="ACL3JB_001612"
     CDS             2616..2861
                     /locus_tag="ACL3JB_001612"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0686313.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3139..3909)
                     /locus_tag="ACL3JB_001613"
     CDS             complement(3139..3909)
                     /locus_tag="ACL3JB_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0686314.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3924..4772)
                     /locus_tag="ACL3JB_001614"
     CDS             complement(3924..4772)
                     /locus_tag="ACL3JB_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR0686315.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4769..6244)
                     /locus_tag="ACL3JB_001615"
     CDS             complement(4769..6244)
                     /locus_tag="ACL3JB_001615"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR0686316.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6568..7923)
                     /locus_tag="ACL3JB_001616"
     CDS             complement(6568..7923)
                     /locus_tag="ACL3JB_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0686317.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7933..8250)
                     /locus_tag="ACL3JB_001617"
     CDS             complement(7933..8250)
                     /locus_tag="ACL3JB_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0686318.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8267..8584)
                     /locus_tag="ACL3JB_001618"
     CDS             complement(8267..8584)
                     /locus_tag="ACL3JB_001618"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0686319.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8599..9495)
                     /locus_tag="ACL3JB_001619"
     CDS             complement(8599..9495)
                     /locus_tag="ACL3JB_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0686320.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9498..10760)
                     /locus_tag="ACL3JB_001620"
     CDS             complement(9498..10760)
                     /locus_tag="ACL3JB_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0686321.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFI
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11040..12218
                     /locus_tag="ACL3JB_001621"
     CDS             11040..12218
                     /locus_tag="ACL3JB_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0686322.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NELIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12446..12892)
                     /locus_tag="ACL3JB_001622"
     CDS             complement(12446..12892)
                     /locus_tag="ACL3JB_001622"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0686323.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12962..13621
                     /locus_tag="ACL3JB_001623"
     CDS             12962..13621
                     /locus_tag="ACL3JB_001623"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0686324.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(13673..14824)
                     /locus_tag="ACL3JB_001624"
     CDS             complement(13673..14824)
                     /locus_tag="ACL3JB_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0686325.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKKEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14839..15570)
                     /locus_tag="ACL3JB_001625"
     CDS             complement(14839..15570)
                     /locus_tag="ACL3JB_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686326.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            15799..15900
                     /locus_tag="ACL3JB_001626"
                     /pseudo
     CDS             15799..15900
                     /locus_tag="ACL3JB_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(15872..16648)
                     /gene="trpA"
                     /locus_tag="ACL3JB_001627"
     CDS             complement(15872..16648)
                     /gene="trpA"
                     /locus_tag="ACL3JB_001627"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0686327.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="ACL3JB_001628"
     CDS             complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="ACL3JB_001628"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0686328.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGSPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(17842..18441)
                     /locus_tag="ACL3JB_001629"
     CDS             complement(17842..18441)
                     /locus_tag="ACL3JB_001629"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0686329.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="ACL3JB_001630"
     CDS             complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="ACL3JB_001630"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0686330.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINHDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="ACL3JB_001631"
     CDS             complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="ACL3JB_001631"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0686331.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(20207..20773)
                     /locus_tag="ACL3JB_001632"
     CDS             complement(20207..20773)
                     /locus_tag="ACL3JB_001632"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0686332.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="ACL3JB_001633"
     CDS             complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="ACL3JB_001633"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0686333.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESISRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         7054 a         4853 c         3753 g         6913 t
ORIGIN      
        1 aataatcaaa gaaattgatt ttttgatatt aaaataaaaa aggagggtag gcagtgttgt
       61 gatcaattat tgctggaggt cttattggtc tcttggcagg taaaatcact aaaaaaagta
      121 gttctatggg aatcatcgca aatgtattcg ctggtttagt cggggcatct gcaggacaat
      181 ctcttttagg tagttggggt tcatcaatcg ctggaatggc tttgctccca tctattgtag
      241 gtgcagcgat tgtgattact gtagtgtcat tctttacagg tagaaagtaa acttttcgcc
      301 agtaaagtta gcaaactatt tttaaatcaa tgacgggaaa aatagtttaa atgttaaatc
      361 gaaaggattg tatatgtcaa aagcaaagaa aatatgtttc attattttct gtattttaat
      421 cttgacaatt ttccttcctg ttttgataga ttatcatcaa gttagtgatc taggtattca
      481 tctacttagc tggagacaga actccgtagt tgaattctat cttgctagat atgtcttttg
      541 ggggacagtg gttctatcaa ctttagtttt attatccatt ttagttgtga tgttttatcc
      601 taaacgttac ttggaaatcc aacttgaaac taaaaacgat acattaaaat taaagaattc
      661 ggcaatcgaa ggttttgtta gaagtttggt gagtgatcat agattgatca agaacccaac
      721 tgttcatgta aatttacgaa aaaataaatg tttcgttcat gtagaaggta aaattcttcc
      781 ttcagacaac atcgctgaca gatgccaaat aattcaaaat gaaataacta atggattgaa
      841 gcagtttttt ggtattgagc gtcaagtaaa acttgaagtt gcagtaaaaa attaccaacc
      901 aaaacctcaa aacaaaaaga ctgttagtcg tgtgaagtaa ggaagtaaaa aatggaatgg
      961 cttaaacaat atcgatatcc aattatcgct ggtctcatag gcgtatttct ggcttgtttg
     1021 attgtctcct ttggcttctt caaaacaata tttgtattga ttttaggagc actgggagtt
     1081 gcagctggat tatatatcga aaaaaactat atagataaat aaaaaaataa aaattactaa
     1141 tttaattaaa ggagtttcat atgtcaaacg aaaaaaacac aaacactaac gtagaaaaga
     1201 aagatgctac tgttgtagct cacgaaatca aaggggaact tacttacgaa gataaagtta
     1261 tccaaaaaat cattggtctt tcactagaaa acgtttcagg tcttttggga atcgatggtg
     1321 gtttcttctc aaatcttaaa gaaaaaatcg ttaacagcga tgacgtaaca agtggtgtta
     1381 acgtagaagt tggtaaaaca caagttgcag ttgacttaaa cgttattgtt gagtaccaaa
     1441 aaaatgttcc agctttatat tcagaaatca gagaaatcgt atcttcagaa gttgctaaaa
     1501 tgactgactt ggaaattgtt gaaatcaacg taaacgttgt cgacatcaaa actaaagaac
     1561 agcatgaagc agactcagta agccttcaag atcgcgtatc tgacgttgct gaatcaacag
     1621 gagaattcac ttcagaacaa ttcgaaaaag ctaaatctgg tcttggatct ggtttctcaa
     1681 ctgttcaaga aaaagttagc gaaggtgtag aagctgttaa aggtgcagca aatggtgtag
     1741 tatctcacga aaacactcgt gtaaactaag ataaaataaa tataacagga gaaattatca
     1801 tgtcagtaga agaaaaatta aatcaagcta aaggttctat taaagaaggt gttgggaaag
     1861 ccatcggtga tgaaaaaatg gaaaaagaag gagcggctga aaaagttgtt tctaaagtaa
     1921 aagaagtcgc cgaagatgcc aaagacgctg tagaaggtgc tgtagaaggt gttaaaaaca
     1981 tgttgagtgg cgacgataaa taaggttaaa agttacttta tctttttggt aacattagtc
     2041 aagatgattc tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta
     2101 attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat
     2161 gtcaattctc acttgacgct tccctctcag atgacatctc ttataaccca aacaaacctt
     2221 tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt
     2281 ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata
     2341 cagtctcttt tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct
     2401 gtttgctttc tatctcccct ttttcatgat atattttcgt acaggtgctt caatagtttc
     2461 tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca
     2521 ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa caggtatagt caattgattg
     2581 tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc
     2641 tggcacaatt tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt
     2701 caaaatggaa agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat
     2761 gtccaagaca gcggtgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc
     2821 caaagcagac agatttcaac gaagtcagtc aagaatttta ggctgggtaa aaactcaatt
     2881 tcaggagaaa atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa
     2941 cacctgatat tatacatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat
     3001 cccacctaaa tcctttggat accaaatacc tcatcaggta ttttctgagt tggtaagact
     3061 gtctagctta atttgacaaa tggagggcgt taaatccagt ttttacagga agtctattta
     3121 aatattttca cactgacctt acaaaatatg aaataaatta tataaagtca ttcccatgac
     3181 aaagaataac atccctttaa aacagtatct tacccaattt tcaggtaaga cttttgatac
     3241 aaccgtcccc aatacccctc cgcatataga agcaagaaaa ataactggaa caggtgctaa
     3301 atgatactga tttaaacctg taaccacaac aattgtagcc aaatgagaca actgggaaaa
     3361 gaaaataatt gcaagagaat acatcgttgc ttcttttatc gaaatagaaa aaaacaccat
     3421 caataaagat acattgagcg gaccaccacc aatccctaaa aaactagaaa tcaagcccaa
     3481 tagaagacca caaatcatat agaatcctat cttatcaaat tgataagttt ttttaaaatc
     3541 tgttaaaaca aatgatacaa gtaacatcac aaatagtaaa atcatttgaa caatagatac
     3601 tagccgtact gataattgag ataacaaaac ttgaaaaata agatgaccta gaaaccctcc
     3661 taaaacagaa gaaaaggata ccgtaaaaat caatctccat tttatctctt tactttgtga
     3721 aaatcttttg attgttgaaa taatcgccat tataaaaaca gagaaactag aataaaaagc
     3781 aatatcactg accgaatggt atccaaaact atccataagt ggcttaatta taattccacc
     3841 acccatgcct gatatagaac ccaatccact agctattata atgattagaa aataaataat
     3901 ctcaaccact ttttaagtcc atcctattct ttcaaacatc taaaacctag atggctacta
     3961 gtggaagtag aaatacatcc atttctagca gctactcggt atcgattaca ataagaacaa
     4021 tgacataaaa aggaacctcc tctgatagca tactcctcat cttgtatccc atattttggt
     4081 aactcatagt catcttcatt aaaactagct aataaggtat atctcggatt gcgacaccat
     4141 tcccaaacat tcccaatcat ttgatataga ccaaaatcat taggtaaaaa ttcatagaca
     4201 ggagccgttc ctataaatcc atctaaggca gtattttcat aaggaaatct tccttgccaa
     4261 gtattggcat gataatatcc accttctaaa agagtatctc cccaaggata ttcagattgt
     4321 cttcctcctc tagcagcata ttcccactgt gcttcagtcg gtaaagacat tccgctccaa
     4381 ttacagaaag ccaatgcatc ttctaaagca acatgaacta ctggatggtc ttctaaaccc
     4441 actagattac tgttctcacc gtagggatgt ttccagcaag cgttcgaaac ttgtaaccac
     4501 cacggagccc cagcaggatg aggatatccc tccctttctg cctccggaac gaacaatata
     4561 aaaacaaaag accactcttg tcgctcagct agtgttttat agcctgtttc tttcacaaat
     4621 tgagcaaatt cttgattcgt aactggagta tccgcaatgg aaaaatcctt tacactaaca
     4681 gcgacttgag gaccttcaaa atcatctaaa aagccctctt cagaatttgt tcccatcata
     4741 aatgtcccac ccttgatttt tttcattttc atgattgact atcccccgtt ttcgttagag
     4801 ttggcgttat tttagaaagt tcaacaggaa ctaactcttc atccacaaca aaaccttctt
     4861 ctctatatct aagaaagtct actaattttt tcttcatctg acgaacaata ggttggtatt
     4921 tttcacttgg atacaaatca ttcatttcat gcggatcttt tttcatatca aataactgat
     4981 aatgatttaa aacaggaaac cagataaatt tccactggtc tgtcaagata tattgactag
     5041 aatcttttcc taaagcatgt tcaccatgaa attctgttcg ccacccctcg tactgtccaa
     5101 ataataaatt cttaacactc cgtccatcta gttcatctgt agtagttcct cctgccaaat
     5161 ccacgagtga aggaaaaata tcttgaattt tcactaattg cttgattgtt cccctattac
     5221 cagctatcaa tccagccgga tcgtaaataa acgaaggaat gtggatactt ccctgataag
     5281 gatatccctt tctaaacaga taatgttcac caagctgatc tccatgatcc gaaacaaacc
     5341 agataatcgt atctttatca tgacgaaatt cttttagggc agtcaaaaag cgactaattt
     5401 gatggtctat atgagtaatc aatccaaaat aagcagcaac cattcttctt tgatcatctt
     5461 cctttaattt ccctcttaaa gcataaatag acggaatttg cttttctaat acttcccaat
     5521 tcccgatatg caaatcgaga aattgaggca agcgttccat atacatatca aaatagtatt
     5581 ttgggggatt taatggagca tgtggttttt caaaagacat tttgagaaaa aaaggaaccg
     5641 ttggatctct tctttgtaaa aatgaaatgg actcactcac aacccagttt gttggatgta
     5701 acttctcatc tttatcccaa ggtctagctt cccaagaatt acaatccatt ccgtcatcaa
     5761 tcaaatcaac atcataacca actttaccct ttaaaaaggc tagatagtca ctagcataat
     5821 caaattgact tccataagcc ttatcatact ttctatcaac atgtagatac ccatcgtgaa
     5881 gtaagacatg atcaaaccca agtctctgtc tggaaggaaa aacatgcatc ttaccaatac
     5941 actctgtttg ataacccata tctttaaaga cttttggaag agtattagta aaattccaag
     6001 gcacctcatc ttgataacca actcgtccac ttttatcttg gtctaagcca gtcaataaag
     6061 ctgccctagc aggaacgcaa gaaggaactg gagaataggc attttcaaaa ttataaccta
     6121 cactagccat catatctaat gttggagtgc taactagctt atccttacta ttcaaggata
     6181 aggcgtctgc tctcatttga tctacaacaa tcaaaataat atttggctgt tttgtctgaa
     6241 ccataaaatc tcctttctaa tatggcaaaa gaggcacaag aagatatcta cctttactgc
     6301 acccctttct atatcaatct ctctatataa aacaataaca ttcttgttat gttttataga
     6361 aaaatgaact aaaatatgac taaatcgatt aggaaattca aatcattttc tagtactatt
     6421 ttagaagtta cagtgtacta ttccaacttc aataaactat aaacctttgt ctaataacaa
     6481 ttttagtgga gataagaaat cctacaccta actcaatctt acacgtaatc tatttctatt
     6541 ttatcacaaa aaacgcaagt aagaccatta actcaattca gttttatctg ccattttcac
     6601 aaatgggaaa taagtcaaga cactaataat caaacaaaca actgataaga tgatggcacg
     6661 ccaatcaaat gctgtagaga agcaaccata taaaattgga ggcattaccc aagtaacatt
     6721 ttgtgtaaca ggtgaaacaa gaccccagct tgttgcccag taagctaccg ttgccatgaa
     6781 aaccgggcta agtacaaatg gtataaatag caaaggattc aagacaactg gtaaaccata
     6841 atttaccggc tcaccaatat taaacagaac tggtgctaga ccaagtttag caacttttcg
     6901 ataatgactg tttcttgaaa aaattaaaat agcaagtacc aatcctaatc ctccaaacca
     6961 gacaaacgcc ccaaaagacc cacttgtcca tatataagga atcggttcac ctttttggaa
     7021 agcatccaga ttcgctaaca tagcaactcc aaacagccct tccatgatgg gagccaatac
     7081 atttcctcca tggagaccaa aaaaccagaa taacttattt aaaaagatca tcagaataac
     7141 tgcaaagaaa ctttgagaca aacctagtaa tggcgtttgt aacaccttgt aaacccaatc
     7201 aatcaataag tcattgctaa gtaaatggaa aacataagtc aagatggcta ctatatacat
     7261 cgccataaat cctggaatga tagaagtgaa cggcttagca atcgcagggg gaactgaatc
     7321 tggtaacttg attacccagt tctttttcat tactttacag aaaataatag aggctaaaaa
     7381 tccaatcatc atggctgtaa agtagcctct ggcattaata tggtttcctg gaatcacatt
     7441 cccaatagtt accatcagat ttttaccatc aaatgctaga ttatcaattc cttgtaagat
     7501 ctgatctaat ttcacatctc ctacatttgc caaagggaaa ctctttgtaa ctgtacttcc
     7561 aatcgaaatg acaaacgaag caagtgatac caaaccagca gaaactgtat caaccttgta
     7621 aatcttagcg atattcactc ccaagcaata gatgaacaac aaggaaacaa ttggtatact
     7681 tcccttgaat accaaattat tgatgtcaac aagccactga aaggttttcg taatactttc
     7741 taggtgaaat tgttgtggta aatccactag aaaagcattt aataacaaag caatggaacc
     7801 tgtcataata acaggcatag tccccacaaa tgaatcacgt aaagcaacta aaaacttctg
     7861 attcccaact ttcattgcaa ttggagaaag tttttcttgc attttatcca acattgtatt
     7921 catactaaac tcctaatttt tttcaaatcg ttcgtatact tctaccactt ctttcgccaa
     7981 gtcaacaaaa gtcagactcg tcattaaatg atcttgcgcg tgtaccatca agaggctaat
     8041 tgatgtttct tccccctgtg cctctcttgt caacatttct gtttgagcct tatgcgcctg
     8101 taataaggca gcattcgcat cagctaatct tcgattggct ttagagaaat cccctttttt
     8161 tgctgcctga atagcctcca tagcattact tttggcttcc ccaccataca taattagccc
     8221 cattgcagat tctaaattac tttcattcat agcattctcc tcaatcttag tctaataaac
     8281 tttcagctaa atctaagact ttagaaccat tcatcattcc ataatctgtc atcggaataa
     8341 ccgccacagg aatctgtcta tcttttagtt tttcttgaaa gtcccctagt aaatagcgaa
     8401 cttgagggcc taaaagcaac acatttactt cctttgttgc tacaatttct tctgcttcag
     8461 gagctggaac tgcaaaaatt tctgcatcca accccttatc ttctgctgcc ttttgcatct
     8521 ttgtcactag cagacttgta ctcatacctg ctgcacatgc taacataatt gttactttag
     8581 ccatagctta ctcctttatc acctatttac tgacctagcc aagcgagata ctgtatgtct
     8641 cactcctcta attgccttgc tcaatgcata aatattatcg actgttgcca gtcccccata
     8701 tcctgcgtca cctatatgtt gaatatcaac tccacaaatt ttatttctaa gtgcaatttc
     8761 cttgatagta tctgtatcag atgtttcttg gctagtacca atagcactca atacaagacc
     8821 acccttacta tgaacgagat caacgacttc acgcaactct tggtcatgaa aggctggaac
     8881 ggttccaact gctggaacaa gtatcacatc cgcacctgct tccaacaatt gctctgcgac
     8941 agaaagctct gccacaggct cattcactcc tgccccgtgc attttaccag ctataatcaa
     9001 acctgagaaa ttctctttag cagattgaac tgctttgata atctcttgat tgctaactcc
     9061 tgttccagga tttccagtca aacagacaaa gtcaaaacct aactcctcta ttcgcttcaa
     9121 tgtttcaaca ctagcaacac gacctgcaac aatttcctgt gtttcctcta gcatctttgc
     9181 agatgggtca atcggttcca aatttacacc aattggacaa gcaacaagct ggtgtaagcg
     9241 atgaataaca tcatcacctg aactatccaa agcataaatt ttaggctcaa aaacatcaac
     9301 acaattcaat aaaatcatat cagctccaaa agctctagca atttcagaat tagttatatc
     9361 cccaacaaat gtctcacgag taactacatt ttcagataga acaactctac cttcacttgc
     9421 taaaatactt tgttttaatt cttcagcatt catctgtaat atctcagatg gatttgcact
     9481 aattaaacgt ttcattctca atcctccaat aacttaaacc gtttttcaat agctattaca
     9541 aatggtaaat aaagtaagac atccaaaaca atcaatacaa tttgtaataa tgaaccagaa
     9601 atacttcctg tagcaagtaa accacttata acaggtggca tagtccaacc tggatctgta
     9661 taagttagcg gaaccaaacc tgatgccatt gctccccacg ctactagtaa gttaaacatt
     9721 ggagctaaga taaatggaac tagtaacaaa atgttcaaaa caataggaac gccaaacatt
     9781 gctggttcat ttatattaaa taatccaggt ataacagtta taggtgccaa agtttttagt
     9841 tgtttactag ctttcttctt atgtgctaaa tatcctaacg caagaactaa acctatggtt
     9901 gcaccaccgc cacctatgaa tacaaaatta tcgataaata cgctagtaaa aatatttgga
     9961 agagtttctc cagtttgata agctacttta tttgcatcta gattagctaa ccataacggt
    10021 ttcataactg cattaacaac atttcctccg tgtaatccta caaaccaaaa actactatta
    10081 aggaaaatta agataagaag accaataaca ttatttccta aaagtccaag tggacctccc
    10141 aaagctactt gagcaatttc atgaagatta ggtaaactta atttatctaa agttgcataa
    10201 acaatcaacc aaccaacaat agtcactgca ccaggaataa tggcactaaa gcttttagat
    10261 actgctggtg gaacaccatc cggcattttt atctgtatat tatgatttat aaaccattgg
    10321 tagatatagc cattaatcaa tcctaaaatc atagcaacaa ataaaccttt tgatgccatg
    10381 aaagcggtag gcattcctgc tccagcctct cctgtaatga aaggcgtaac tgtaataaaa
    10441 gatgataatg acacaatacc agcaggaata ccatcaactt tgtattgtct agccataaag
    10501 taagcgatac caaaactagc tacaagacca agtaatccaa aactactatc aacacccttc
    10561 cataaataat cagcaacacc aatatcaccc agatattttt cccatcctgg aataggaaaa
    10621 cttgcaataa ccattagtaa tgaacctatc aacaataaag gtatagttag agtaataccg
    10681 tctcgaatag aaaccaacgc tttattatta cccaatctag ccgctactgg aagtaacttt
    10741 tcttgtaata atttttccat aaccttttcc tcttaaatat attttattat caaaagttat
    10801 caattatctt tattttttga cgtcaagttg ttatttgatt atcttttgtt atttatattt
    10861 tacaactata agaaagcctt gtcaaggatt tgtgtaaata tttgattatt ttttattatc
    10921 aatatataat aaaaagagac cagtaagcaa tgaaaagctt aaaaagatta acatctacat
    10981 ttatccatag caaaaaatca taggatttta agaatctgac aactaggaag aaaactaata
    11041 tgaccttatc taagaaacaa ttacaactac gagctaaaat actggaaaca gtttacacat
    11101 taggtcccat ttcacgaatt gaaatcgcta ctaaaacagg aataacacct gcaacaacta
    11161 gcagtatcac aaatgagctg attaaagaaa acattctctt agaacttggt gaagacgaac
    11221 acgatacaag cgtagggaga aaaaaaatcc tgctagacat tcaagctaaa cgattttact
    11281 acattggttg tgaactatct gaaaaacatt tcacttttgc tttaggagat aatctaggaa
    11341 atatcttaaa ggaagagaaa gaaattgtta ctaaacagtt aatccaagaa aagggaaatc
    11401 aactcattaa ccagacacta aagcaattct taaataactg ctctgattat gaaatagaag
    11461 caattggaat cgcgctacct ggtcgctatt tagatgatta taaaataaca acaaacaatc
    11521 ctttatggca acatatcgac ttagaaatga ttcaatccca ctttgataag cctttgtttt
    11581 tctctaacaa tgttaactgt atggctatag gtaaacgcct atttagtcgc caacagaatg
    11641 accctaattt tgcttatttt cattttgcta gaggtatgca ctgttcttat atctacgacg
    11701 gaaacattta tgggaaagga aatctaatga ttggagaaat agggcataca gttgtttcat
    11761 ctgagggaga agaatgtagc tgcgggcgca agggatgctt acaaactttt gctggagaat
    11821 cttggttaat caaaaaatca aaaattctat atcatcaatc tccctattct ctacttccta
    11881 gtttagtcaa aaatgccgat gatattgata tccaagttat tttaaccgct tatcaattag
    11941 gtgacactgg aataatcaca cttatccatc aagccttact ctatcttagt caaaccattt
    12001 taaatatcag tatgatgatt gactctcaaa aaatctacct acatagtcct ttactaacaa
    12061 atcaacacat catccaaaaa ctatatagtg aaatgaacta caaacccaaa ctgctctata
    12121 atcgcctacc tgaagtcatt attgaacctt acaatgattt tacagccgca cactcagcta
    12181 ttgcactttg tttgtatcat acaattctac attcttaatt ttctattaca tttaataaat
    12241 aggctaaaaa gagggagtat atcataaaaa gcgaataaac ctgttttctg aaaatcagaa
    12301 ttctgttttg ttcgctttct ttatatttgg aattatactc ctatctcccc tttttcataa
    12361 tgtatagtga aatgaaataa taacaggacg aatcgatcgg gacagtcaaa tcgatttcta
    12421 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatat tttcgtacag
    12481 gtgcttcaac catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt
    12541 gatttgcctc gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac
    12601 taacaaattt ccttaaagcc tggctaccta agccttgccc ctgtttctgg gggttgataa
    12661 aaaatctccc gatatgaaga ttgctgtctt ctagcctgat tttctggata agtcccacaa
    12721 actcttgttc atcaaagatt gaaaagactt cttccaaggc ttgaagggtc agtagaaaag
    12781 gaatccttga tcccatccat tgttcttgaa aggatttgcc tagggagttg gaccattggc
    12841 atacaaattg agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct
    12901 caccatctta tctatgtttc tccattatac tatttctccc attttttacg aatagataag
    12961 tatgattgat ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt
    13021 cattgaccgt tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca
    13081 gactcccttg cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg
    13141 ctgtcgctac tgcaaggtcc gctatcctgt ctggtatgcc ctctttgaac taggcttagg
    13201 actcctcttt ctgctttact cttgggaatt gctttccttg gggcaagtcg tcctaatcac
    13261 cgctggtttg accttgagca tctatgactt tcgccatcag gaatatccct tactggtctg
    13321 gatgactttc cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt
    13381 ccttgctctt ggaattttgg ctcattttat cgatatccgc atgggcgcag gggatttcct
    13441 ctttttagct tcttgtgctc tcgtctttag cataacggag ttactgatct tgattcagtt
    13501 tgcttctgcg acgggtatcc tagcctttct cctgcaaaag aaaaaggaaa gacttccttt
    13561 cgtacctttc ctcttacttg ctacttgtgt gattattttt ggtaagctac tgcttgtctg
    13621 ataaaatcca atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat
    13681 tatttctttt gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat
    13741 actgatcaaa aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac
    13801 tttgtttaga cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa
    13861 tactctttac tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt
    13921 tgtaaccttt ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc
    13981 ctaacttaaa agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata
    14041 aaatataact atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa
    14101 actctttttt tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat
    14161 cgccatcttc attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta
    14221 agtcaaaatt tcgacgtaca gatgatttat tcgttcctaa cacaatataa ggtcttccca
    14281 attttgacca tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga
    14341 tgcctgaacg ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt
    14401 ccctggcata aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta
    14461 cattacttag gtcatgaatt ataatattag gtataattac aaaactttca aaataatcaa
    14521 tcaaactatc taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta
    14581 ggtctgcatt tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt
    14641 caaaataagt taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag
    14701 gtttcgtttc gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag
    14761 ctaattctgc tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa
    14821 acatttacat actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc
    14881 aaaatcttct gtttccgata attctgaaaa attaggaata tcttgatatt tagcttcttc
    14941 gaaatggtac gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc
    15001 agttcgtgca tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc
    15061 ataagttaaa atcataaatt tttcgatatt cgaattttta gtagcttgtt caatttcttg
    15121 aatcatttca tcagaaacta actccatctg aattggaaag gaatgactat tttcatcatt
    15181 tttgtaggaa gaatgttgat taagataaag tgtattcatc tgagcatatt caaataagta
    15241 gccactctta tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat
    15301 aattaacaat actttcccat atttttctgt atttgtttca aattctaaat atccccaagt
    15361 ctgtcctgct aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat
    15421 atgattaggt cgcgtccatg cataaccatt cgacactatc attgtctctc ttttttctag
    15481 acgttcatct acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc
    15541 aagcgaatca aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg
    15601 aattatacca ttttcttaaa gaaattacta caataattat ctttttctta aagttctgtg
    15661 tcagagtaat ttagaaaatt atatcttcta tagtaaaatc aattaaaaac tgaacaaatt
    15721 tattgggaaa ttcaaatcgc tttctgaaaa tattttagga accgtagtgt aatattccag
    15781 attcaattca ctataaaact gacctttctc ctgcaaaaga aaaaggaaag acttcctttc
    15841 gtgcctttcc tcttacttgc tacttgtttg attatttttg gtaagctact gcttgtctga
    15901 taaaatcctg aatcggctct ccttggtgga gagcttttac tatttttgaa ccgacgataa
    15961 caccatctga caccgcattg aagcgttcca gatcggcttg actagataca ccaaaacctg
    16021 tcaagactgg gatgtcggcc acttgatgaa gttgcgccaa gtgcttgtcc aaatctgcac
    16081 ggtaattgcc tgatttccct gtcactccat tgatggcaac ggcatagatg aatccctccg
    16141 ccccttcaat caactctttc tgacgctcaa ttcctgtggt caagcttact aaaggaatca
    16201 aggcgatatc tgtatctgcc aaaaatggtt ctacaaagtt ggcatgttca tgaggcaggt
    16261 ctgggataat caagcccttc acagctgtat cagccagatc tttgacaaag ttctccacac
    16321 cgtactgaaa gagggggttg aagtaggtca tgatgaccag tggaatctct gtttcaatgg
    16381 ttttcaaggt ttcaactaaa gcctgggtag aggtcccgtg ggctaaactg cgcaagccag
    16441 cttcttcgat aacaggtcca tctgcaacag ggtctgaaaa gggaataccc acttcaattg
    16501 cagagacacc caaatcttct aaaaagtgaa ttgtttcagc aagaccgtcc aaacctttct
    16561 cgtggtcacc agccatgata tagggaacaa aaattccttt tccagttgct tttatagcat
    16621 tcaatttttc tgttagtgtc ttaggcatga gcttctccct tctttgctgc atctgcttcc
    16681 aagcggtctt tgacttgaac cacatccttg tccccacgac ctgataggca tacaatcata
    16741 gacttttctg gtccaagttc tttggccaat ttcaccgcaa aagcgatagc atggctagat
    16801 tccaaggctg ggataatccc ttccacacga gacaagagtt gaaatccttc caaagcttct
    16861 tcgtctgtca cagggacata gctggcacgt ttgatatcgt ggtagtgaga atgctctgga
    16921 ccgataccag gatagtccaa acctgctgag atagagaagg cttcaagaat ttgaccatgg
    16981 gcatcttgga gcacatccat gagagaaccg tgaagaacac ccggactacc cttggtcaag
    17041 gtagcagcgt ggtgctctgt atccacacca agccctgctg cttcagttcc atacatagct
    17101 actgactcat cttctacaaa gggatggaag agcccgatag cattcgaccc accaccaaca
    17161 caggctacta gggcatctgg cagatctcga cctgtcaagt cacggtactg ttgtttagcc
    17221 tctcgaccga tgacactttg gaagtcacga acgatttctg gaaatggatg aggccccaag
    17281 gcagaaccaa ggatatagtg ggtatcgtcg atattagcca cccatgaacg aagggctgca
    17341 ttgaccgcat ccttgagcac gcgcgaacca tctgtcacgg cctcgacctt agctcccaaa
    17401 agctccatac ggaagacatt gagggcttgg cgtttgacat cttcctcacc catgtagatg
    17461 gtacattcca tgttaaagag ggccgcagca gttgcagttg ccacaccgtg ctgaccagca
    17521 ccagtttctg cgataatttt ctttttaccc atgcgtttgg caagccaaac ttgtcctaag
    17581 gcattgttaa tcttgtgggc tcctgtatgg ttaaggtctt cccgtttgag ataaatcttg
    17641 gctccgccga tatgctgggt caagtttttt gcgtagtaaa ggggagtttc acgtcccaca
    17701 tactggcgca aaagctggtt taattcctct tggaaacttg ggtctgcctg actttcacgg
    17761 taggccttct ccaactccaa aactgctgtc atcaatgttt ctgggacaaa acgtccgcca
    17821 aattttccgt aaaatccatc tttatttggt tcttgatatg ccattcttta ccctctctat
    17881 aaatcttcta atcttttcat gatctttttg tccatctgtc tccactccgc ttgatacatc
    17941 tactgcatag ggagtaaagt gttgaattgc ttttactaca ttatcttcat taaggccacc
    18001 tgcgataaag aagggctgtg ctagtccagt cgtatccagt tgaccccaat caaagggctg
    18061 gccactccca gccacagggg catcaaagag tagatagtct gcctgagaat tgggcacatg
    18121 accctctcca tctacctgca cagcctgaat gctagcacaa ggcaaattct caaataaatc
    18181 atctgccacc tgaccgtgaa cttgaaccaa gtccaagcca actttgtcaa tcgcttccag
    18241 cagttctgcc cgacttggtg aaacaaatac accaaccttt ttgacatctg caggaataag
    18301 ctttgccaac tcagctgcct cttctaaagt cacctgtctt ttactaggtg caaagacaaa
    18361 accgatatag tcggctcctg ctgaaacggc tgtttccacc gcttctttgg tcgatagtcc
    18421 acaaatttta acctttgtca atctgcaact ccttgattct ctgggccaca ttttctgcct
    18481 gcataagagc tgtccctacc aaaattccgt taaagtatgg ggctagtcgt tccgcatcct
    18541 gccctgtgaa aatggcagat tcagaaatgt aatagcgacc ttcctcaaag taaggggcta
    18601 aatctacact ggtctgcaag tcgacctcaa aggtagtcaa gttgcggttg ttgaccccga
    18661 taatctcagc accaagtctg tgggctacct ctagttcagc tagattgtga gtctccacta
    18721 agacttccag accaagctct gtcgcgtagt catacagttc cttgaggcgt tcttcggaca
    18781 aggctgccac aatgagcaag ataactgtcg cacctgcatt gcgagcgcgg atgatttgct
    18841 tttcatcgat gataaagtct ttgttgagcg tcggaatctc tacctgactg gaaatttccc
    18901 gtagataatc caaatgccct ttaaagaaaa cctcatctgt caacaccgaa atcatcactg
    18961 ctccgttttc ttcataagtc tgggcctgtt gcacaatatc cacatcgtga ttgatatctc
    19021 ccaaactagg gctagctttc ttgacctcag cgattacctg caagcggtcc tgatgattct
    19081 tcaaaaactc tgccaagcga taggtctggc gcagaggctg gatttgctcc agcttcatct
    19141 gctccacctc acgcaccttc tgctctaaga ttcgtgctaa aaattcctga ctcatttttg
    19201 gtactcctgt aacagtctga gtttttcaag ggccttgcct ctagcaatca cttgacgggc
    19261 caaggcaact ccttccttga tgctatcaat cttaccatta gcatagaaac caagaccagc
    19321 attcaagact gtcgtttcca agaatggact tgcttcgttt ttcagaacgc taagcaaaat
    19381 ttctgcattt tcctgagcat tcccaccacg aatatcttcc atagcatagc cttccattcc
    19441 caaatcctct ggagtaaagc ttgacaagct gatttcgcca ttttcaagaa gtgcaatctt
    19501 ggttgttccg ttcaagccag cttcatccaa cccttctggt ccagcaacca cgatggcacg
    19561 tttgcgaccc atatttttca aaacctgagc tgtactttct aggagttctg gacgactaat
    19621 tccaagaagc tgtgtttcta aagccattgg atgaatcagt ggaccagtca agttcataat
    19681 cgttggaatt cccaattcca aacgagctgg catgatgtat ttcatagctg ggtgcatatt
    19741 tttagcgaag agaaagacga ttccagtttt atcaaagacc ttacctagtt cagctggttt
    19801 gaggtcaaga ttgattccca aggcttcgag gacatctgcg gaaccagatt tagaagaaat
    19861 cgagcggtta ccatgcttgg ccatgtgaat accgccacca gccaagacaa aggctgcagt
    19921 tgtggaaata ttaaaactga aagacttgtc cccacctgta ccacagttgt ccatggcatc
    19981 atgaatctca gttggaatat gctgggcatg tcctctcatg acttgggcaa tggctgtgcg
    20041 ttcttcaggt gtttccccct tcatcttaag agctaagagg agagaagcaa tctgcgcttc
    20101 agttacacgc ccagttacga tacgctcaat gacatccgtc atttccacac ctgataaatt
    20161 ttcaaatttt gctagttttt caataatctc tttcatccta gtttcctcac tttacaacct
    20221 tctcgataaa attccgaata gaagacaagc cgtctggcgt tccaatgctc tctggatggt
    20281 actggaagcc ataaatcggt aggtttttat gttgaatccc catgatggct tggtcatcag
    20341 tcgaacgagc tgtcacttca aagtcttctg gcatttcctc aatcaaaata ctgtgataac
    20401 gcatgaccgc acgtccttcc tcaatacctt gatacaaaac agatggcgct tcaaagttga
    20461 tattgctctg tttcccatgc atgacttttg gagccaaacc tagcttacca ccaaagactt
    20521 ctgcaatggc ttggtggccc aaacaaatcc caagaatcgg cttcttgcct gcaaaatcac
    20581 gaatcatgtc ttccatcttt ccagcatcaa ctggccaacc aggaccagga gaaaagacca
    20641 gaccatctgc tttttcagct tcttcataca gcttggaatc atcatttctc agaacctgaa
    20701 cttctgcaaa attcccaatg tattgggcca agttataggt aaaagaatca tagttgtcaa
    20761 tcaataaaat catggtctta gttctccaat tctagtcata gattttgctt tgttaatggt
    20821 ttcttggtat tcgttttggg cgatagagtc gtagacaatc cctgccccag cctgcacata
    20881 ggctctttga tttttgagaa tcatggttcg gatggcaatg gccaaatcca tatcacccgt
    20941 cgcagacaag tagccgattg ctcctgcata tacgccccgt ttttccgttt ccagttcata
    21001 gatgcgtctc atcgcccgaa tctttggtgc tccagaaacg gttccagcag gaagtgtagc
    21061 tttcaaggca tccatggccg tgagttctgg aagcaaacgc cccttgacca cgctggtcaa
    21121 atgcatgacg tagcggaaga gctccacctt catatactta gtaacttgga cactggccgt
    21181 ttcagagatg cggccaatat cgttacgccc caagtctacc aacattcgat gttctgctgt
    21241 ttccttctca tcagagagga ggtcagtcgc caaggtcttg tcttcttcat ccgtagcccc
    21301 tcttggtcgc gtccctgcaa tcggattggt tgtcacgatg ccatttttga cagaaactaa
    21361 actttctgga ctagctccga tgatttgata atccccaaaa tcatagaaat aaaggtaatt
    21421 agaaggatta gtcacgcgga gatttctgta gaagtcaaat ggatttccag taacttctgc
    21481 tgaaaaacgc tggctgagta cacattggaa catatctccg ttacgaatca agtcacgagc
    21541 tgtttctacc attccctcaa acttatgtgg agcgatatgc ggtttgaagt ctaacggaga
    21601 tagatccaaa tcttcaaatt catttggagc aggaatgcgt aattcctcaa gcacttggtt
    21661 caaggatttt tccaaggcct cttgactgcg ctcactataa agtgcatcct ctatgacatg
    21721 tatcttctcc ttcttgtggt caaagaccat atagctctca tagacaaaga aatgcatgtc
    21781 tggcgtccca attgtatcct cagggatttg accaatttct tcataaagcg aaatcatatc
    21841 gtaacccaca aaaccaatgg ctccaccacc aaaaggtagc tctgagtggt gctgactctt
    21901 atgaatcact tcataaagga aatccaaggg atcccgatca atcacttgac cattttgata
    21961 gagaacccca ttttcaaact taatctcaaa aactggatta taggctagga tagaaaaacg
    22021 agctgtttcc ttgtctctcg aaatactctc taaaataacc ttatgttgcc cctttaagcg
    22081 catataagcc aagattggtg ataagacatc tccatgaatg attcgttcca ttgtaatttc
    22141 cctttcagtt ctacttctag tccgtggtga ctgtatgaaa aatccccacg caaaataact
    22201 tgcgtgagga cgaaattcgc ggtgccacct caattatagg atttctccta tctctcattc
    22261 ctgtctcaga tatctcctgt aacaggctgt gcgataaagg gcactccctt gagaatgatg
    22321 ttttcttctc tcgtttcaga tgaacccaac tttacagctt tctctgcttg ttttcagcaa
    22381 ccacaagctc tctgtgagag aaagaactgt aatttttcca tctattattt tttagcttct
    22441 agtaatctgc aatcgcagct aggtccttgc ctccacgacc agagacattg atgaagagat
    22501 gttcatctcg gtacaccttt atactcttcg aaaatctctt caaaccgcgt caacgtcgcc
    22561 ttatcgtagg tat
//
LOCUS       DBEJNA010000036        22136 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEJNA010000036 DBEJNA010000000
VERSION     DBEJNA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.36"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            70..981
                     /locus_tag="ACL3JB_001634"
     CDS             70..981
                     /locus_tag="ACL3JB_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0686334.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            1211..1909
                     /gene="dapD"
                     /locus_tag="ACL3JB_001635"
     CDS             1211..1909
                     /gene="dapD"
                     /locus_tag="ACL3JB_001635"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0686335.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            1977..3107
                     /locus_tag="ACL3JB_001636"
     CDS             1977..3107
                     /locus_tag="ACL3JB_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0686336.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            3119..3658
                     /locus_tag="ACL3JB_001637"
     CDS             3119..3658
                     /locus_tag="ACL3JB_001637"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0686337.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            3642..4319
                     /locus_tag="ACL3JB_001638"
     CDS             3642..4319
                     /locus_tag="ACL3JB_001638"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0686338.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(4391..5290)
                     /gene="galU"
                     /locus_tag="ACL3JB_001639"
     CDS             complement(4391..5290)
                     /gene="galU"
                     /locus_tag="ACL3JB_001639"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0686339.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(5312..6328)
                     /locus_tag="ACL3JB_001640"
     CDS             complement(5312..6328)
                     /locus_tag="ACL3JB_001640"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0686340.1"
                     /translation="MKKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSIILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHETNIKDTIYDIMNNEFKAE
                     NEWS"
     gene            6540..6980
                     /locus_tag="ACL3JB_001641"
     CDS             6540..6980
                     /locus_tag="ACL3JB_001641"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0686341.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIVQKKESVFAK
                     IFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW"
     gene            complement(7095..7526)
                     /locus_tag="ACL3JB_001642"
                     /pseudo
     CDS             complement(7095..7526)
                     /locus_tag="ACL3JB_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7588..8238)
                     /gene="phoU"
                     /locus_tag="ACL3JB_001643"
     CDS             complement(7588..8238)
                     /gene="phoU"
                     /locus_tag="ACL3JB_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0686342.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(8253..9005)
                     /gene="pstB"
                     /locus_tag="ACL3JB_001644"
     CDS             complement(8253..9005)
                     /gene="pstB"
                     /locus_tag="ACL3JB_001644"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0686343.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(9007..9822)
                     /gene="pstA"
                     /locus_tag="ACL3JB_001645"
     CDS             complement(9007..9822)
                     /gene="pstA"
                     /locus_tag="ACL3JB_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0686344.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(9815..10678)
                     /gene="pstC"
                     /locus_tag="ACL3JB_001646"
     CDS             complement(9815..10678)
                     /gene="pstC"
                     /locus_tag="ACL3JB_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0686345.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(10796..11671)
                     /locus_tag="ACL3JB_001647"
     CDS             complement(10796..11671)
                     /locus_tag="ACL3JB_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0686346.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(11838..13169)
                     /gene="pnpS"
                     /locus_tag="ACL3JB_001648"
     CDS             complement(11838..13169)
                     /gene="pnpS"
                     /locus_tag="ACL3JB_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0686347.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(13170..13877)
                     /locus_tag="ACL3JB_001649"
     CDS             complement(13170..13877)
                     /locus_tag="ACL3JB_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0686348.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(13961..14446)
                     /locus_tag="ACL3JB_001650"
     CDS             complement(13961..14446)
                     /locus_tag="ACL3JB_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0686349.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            14432..14989
                     /locus_tag="ACL3JB_001651"
                     /pseudo
     CDS             14432..14989
                     /locus_tag="ACL3JB_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(15304..16995)
                     /gene="argS"
                     /locus_tag="ACL3JB_001652"
     CDS             complement(15304..16995)
                     /gene="argS"
                     /locus_tag="ACL3JB_001652"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0686350.1"
                     /translation="MNIKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            17131..17577
                     /gene="argR"
                     /locus_tag="ACL3JB_001653"
     CDS             17131..17577
                     /gene="argR"
                     /locus_tag="ACL3JB_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0686351.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            17628..20162
                     /gene="mutS"
                     /locus_tag="ACL3JB_001654"
     CDS             17628..20162
                     /gene="mutS"
                     /locus_tag="ACL3JB_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0686352.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            20309..22003
                     /gene="patA"
                     /locus_tag="ACL3JB_001655"
     CDS             20309..22003
                     /gene="patA"
                     /locus_tag="ACL3JB_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0686353.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         6280 a         4383 c         4838 g         6635 t
ORIGIN      
        1 gataattctc taaatgaagt ggccaatcaa tggattgcca cttttttcct ttcgtgttac
       61 aataagggta tgaatcagta tcagaaaaag attgttaacg gaaaaattta ttcgctccta
      121 tccggcttaa tatggggaat ctgtggaatt ttaggagagt acttctttac tcattatcag
      181 gtgtcttcgg gctggattac ctctatgcgt ttgacactgg cagggagtct tgtactcatt
      241 tggtctgcaa tacaattaaa atcgcaagtg ctagatattt ggcgagacaa gaaaaattac
      301 ctgccctttt tagcttatgc tattttgggg attttttcag tccagtattt tttctatctc
      361 tgtgtagaat actcaaatgc tacgacagca actattttac agtttattag ccctgtcttt
      421 atcctctttt acaatcgctt ggtttatcaa aaacgagcgt caaaaagcgc tgttttctat
      481 gttttggttg ccatgctggg tgtttgcttg atggcgacaa agggagatct ctctcagtta
      541 tccatgacgc cgctagctct tataacaggt ttgctgagtg ccatgggtgt tatgtttaat
      601 gttatcttgc cccaaccttt tgctaagcgt tatggttttg ttcctacggt tgggtggggg
      661 atgattttgg caggtttgtt tagcaatgtc ctctcgccgg tttatcagct ttcctttact
      721 cttgatattt ggagtatctt gatttgcctc attatcgctt tctttggaac ggcttttgct
      781 tttttcattt ccatgaaggc tgtgtccttg gtttctcctt tggtggttgc cgttatcagt
      841 gccagtgaac ctctctcttc tgctctcttg agtgttttgt tcttaggatt agtagtggat
      901 tggtccctcc ttctagctat agccttgatt attttaccca tgatattttt gtctatagaa
      961 gaagcgaaag aaagtagata aaaagtcttt tcttaattct aaaagtgtgc tatactagaa
     1021 tagtcaataa aacacgggga gatagttgtg aagagtgttt ttaggttgta tcggtagggg
     1081 cttgctttta ccgacagcac gttttatctc acatccctaa aaaatcatac ctaaaaacag
     1141 acaaaaaggt ttcaaatttg aggccttttt tggtagaata ggtatcatta taaagaatga
     1201 gaggcctttt atgactgcta caaaaatgaa tgctcaagaa attatccaat ttatcgccaa
     1261 tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg caactcgcaa ctgctgtgcc
     1321 tagctctgtt gtcaaactag gaaatgtcct attcggagac tggaaggacg tggctccgct
     1381 tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag caagatgctc gtaattctgc
     1441 agttcctttg ctagataagc gtgctatcaa cgctcgtatc gagccaggtg ctattatccg
     1501 tgaccaggtg gaaattggtg acaatgctgt tatcatgatg ggagctgtta tcaatatcgg
     1561 tgctgaaatc ggtgctggaa ccatgattga catgggtgcc atccttggtg gccgtgctat
     1621 cgttggaaaa aatagccacg ttggtgcagg tgcagttttg gcaggtgtga ttgagccagc
     1681 tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc ggtgctaatg cagtggttat
     1741 cgaaggagtc caaatcggta gtggttcagt tgtcgctgca ggagctatcg ttacccaaga
     1801 tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt atcatcaaag aaattgatgc
     1861 ccaaacccaa caaaaaacag cgctagagga tgcgcttcgt accttgtaat tgtaaaagta
     1921 aaaaagaggc ggaacccttt ttccagcctc tttctgctat atcggaggac agatagatgt
     1981 tagatttgat tcagactaga cgagctttac accagattcc agagattggc ttggaggagt
     2041 tcaagactca ggcttatttg ctggatgtga ttgagaaatt gactacgggc aaggattttg
     2101 ttcaaattcg tacttggcgg acagggattt tggtctacct gcagggaagt cagccggagc
     2161 gaaccattgg ttggcggaca gatattgatg gcctgcctat cgtcgaacaa acaggtctac
     2221 cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg ccatgatttt catatgacca
     2281 ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc caagaataat ctgctctttc
     2341 tatttcagcc tgctgaagaa aatgaagctg gtggtatgct catgtatgag gatggtgctt
     2401 ttggagattg gttgccaaac caattctatg gtctccatgt tcgtccagat ttgaaagtcg
     2461 gccagattgc gactaatact catacactct ttgcaggaac ttgcgaggtg aagatccgtt
     2521 tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc caatgacgcc ttggtggcgg
     2581 ctagttactt tgtgacccaa gtgcagtcag ttgttagccg caatgtcaac ccaatcgagg
     2641 gagcagtggt gaccttcggc gtttttcaag ctggaaccac caacaatgtc atcacagaca
     2701 cagctttttt acatggaact attcgtgcct tgacacagga catgagtctc ttggtgcaaa
     2761 agagggtaaa aacagttgca gaaggggttg cagctgcctt tgatatggaa gtcgaagtgg
     2821 aactcaaaca aggtggatac ctacctgttg agaacaatcc agccttggcg cgtgaactga
     2881 tggacttctt tgacgaaaaa gacggaatcg agttgattga tatcgaacct gctatgacag
     2941 gcgaggactt tggttatctc ctttcaaagg ttgatggcgt gatgttttgg ctaggtatcg
     3001 atagtcccta cgctcttcat caccctcaaa tgagtcctaa ggaagaagtc ttagctattg
     3061 gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc agaatagagg gcttgtatat
     3121 gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag gctttatctc aagaacaaaa
     3181 acaggctata gaccaagctt taaccgagcg aattttacaa cacccctttt atcaagaagc
     3241 caaggtcatc gcaacctacc tctctttttc tcatgagttt caaacgcggg aactgattga
     3301 gcaggcgctg aaggacggca agaaggtttt aatacccaaa acttatccca aggggcgcat
     3361 ggactttgta gtctatgatc cgcagcagtt ggtaaaaact gcctttgcct tactggagcc
     3421 acagggagat ttggaagtgg tggatgtatc tcagattgat ttgattcatg ttcctggcct
     3481 ggcttttacg acggatggat atcggattgg atatggtgga ggttattatg accgctatct
     3541 ggaacatttt tctggtcata ctttgagtac ggttcatcct tgtcaaattc aggactttat
     3601 acctgaaaac catgatattc ctgttcagga ggtattaatt gatgaaggaa atctttgata
     3661 gacgttaccc tgtgacgagt ttcttcctct tagtgacggc cttggtattt ttactaatgt
     3721 tggtcactgc aggcggaaac tttgacaggg cagatacatt atttcgattt ggagccatgt
     3781 atgggccagc tattcgcctc tttcccgagc aggtttggcg tctcttgtct gccatttttg
     3841 ttcatattgg gtgggaacat ttcattgtta atatgctttc actttattat cttggaaggc
     3901 aggtagagga gattttcggc tctaagcagt tcttttttct ctatctctta tcaggaatga
     3961 tgggcaatct ctttgttttt gtatttagtc ctaaatcctt agcagcaggc gcctctacct
     4021 ctctttatgg gctatttgcc gcgattattg ttcttcgcta tgcaactcgc aatccttata
     4081 tccaacagct agggcaatcc tatctgacac tttttgtggt taacattatt ggaagtgttc
     4141 tgattccagg aatcagccta gcaggccata tcggtggtgc agttggtggc gcatttctag
     4201 cagttatctt tccagttaga ggagaaaaac ggatgtataa caccagccag agattaggag
     4261 cggtagtctt gttcgtagga ctcgccattt tgcttttcta caagggaatg ggaatgtgac
     4321 gaagttgaaa gaaaatttgt gtaatgaaaa aagataaggc attttttgaa ccttatcttt
     4381 ttattttatt ttattccttc tcagtcaatt cttttccaag ttggatgagg taattcttca
     4441 aatcatcttt gacttgtggg tgtttgaggg cgtagtcgat ggatgttttc atgaagccaa
     4501 acttgtctcc gacatcgtaa cgagccccat tgaactcacg agcaaataca cgttgtgttt
     4561 tattgagggt gtcgattgca tctgtcagct gaatttcatt tcctgcacct ggagcttggt
     4621 tttcgaggat ttggaaaatt tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc
     4681 taggagcgtc ctctggagct ggtttttcaa caaaggtttc aacactgtaa agaccatctt
     4741 ttccttcgcc ttgcggagca ataaccccgt aagcagatac ttcgtcatga gggactggca
     4801 tgacagcgat agtagacgcg tgggtacgct cgtagtcatc catgagttgt ttggtaagtg
     4861 gaacagcctt ttcgtctgtg atatccatca agtcatcacc aagcataacg acaaaaggtt
     4921 catttccgac gaaagcctta gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt
     4981 ggcggataaa atgcagacgc atgtcagttg ttttatcaac tagcttcaaa agatctgttt
     5041 tccctttttc tttgaggtta tattccaatt cgaagtttga atcgaagtgg tcctcaatag
     5101 aacgttttga tttaccagtg acaactagaa tatcttcaat acctgatttg agagcctctt
     5161 ccacgataaa ctggatagtt ggtttgtcta cgattggcaa catttctttg gcaagggcct
     5221 tggttgctgg taaaaatcga gttcctagtc cagcagcagg gatgactgcc tttctaactt
     5281 ttgatgtcat aagaatcctt tctatagagg gttaagacca ctcattttct gctttaaatt
     5341 cattgttcat gatgtcataa atggtatctt tgatattggt ttcgtgataa ataacttggt
     5401 aaatggcctg tgtaatgggc atatagactc caagttcttg ggctagttca taggctgctc
     5461 gagtcgttga aattccttcg attaccatgc ccatattagc ttctatatca gctagggatt
     5521 ctcctcgtcc gagagcatct ccagctctcc agttacgaga gtggatggaa gttcccgtta
     5581 cgatcaaatc tcccacacca gataagccgc tataggtcaa tggactggcc ccgagagcca
     5641 cccctaggcg agtaatttca gccaagcctc gagcgatgat ggctgcctta gcattatcac
     5701 caaatccaag accatgtaaa gctccagcac cgacagcaat aatattttta agagcaccag
     5761 cagtttcaac cccgataaca tccgtattgg tataaagtcg gaagtagtga ttactaaata
     5821 gctcctgaac gtattgagct gtttgtaaat ctttagaagc agcagttatt aaagttaggt
     5881 cacgcacaat ggtctcttct gcatgactag gtcctgaaac aacgacgata tcactacgga
     5941 gatgttcagg aatttcttct tcaagaatga ttgataatcg tttatggcta tcaggttcta
     6001 atccctttga tgcgtgcatg atgataacct tatggtccaa ggtttgtgca acttgctggg
     6061 caacaagtcg tgtcactttt gttgggacaa caaacaaaat tgcatccaca tctttcaatg
     6121 tttctgctaa gtcggtgtag gcaatgatat tttcgtctag aacgacatct ttaaagtagt
     6181 gcttattagt atggtgtgta ttaatttcat tgatttgctc gggaagattt ccccaaatac
     6241 gtacctcgtg tccattgtca tttaagactt gtgaaagggc ggttccccaa gaaccaggcc
     6301 ccaagacggc gacagtttgt tttttcatga tttcctcctt gatagggttc tttctcttat
     6361 tctatcatat tctaggggat tttgcacttg cattactggg gtatggtgga aaaatacaca
     6421 aaaaccgaga cgaagggata aactcttagt ctttagttaa aatgagaaga aatctgatag
     6481 atagtttgat tcagtatatg cttataatag aggtaaacaa ctcaggaggt tcttgtaggt
     6541 tgcgagagtt tggcgaaaaa attaaaagat tacgtttggc taaaaaaatc agtcgttcag
     6601 aattttgtgg tgatgagtct gaattaagta tccgtcaatt aattagaatt gaaaatggag
     6661 aatccagacc aacactaaca aagttaaaat atatcgctga acgtttgggg gttgaagatt
     6721 acaagttgat gccaagttat atagagttgg ataaggaata cctagaattg aagtatttct
     6781 tgatgaggac tcctacatac gaagatgaaa ctatcgtcca aaagaaagag agtgtttttg
     6841 ctaagatttt tgaagagtat tatgataggc tacctgagga agaaagattt atcatcccaa
     6901 attattcata tctggcacta acgaactaca cagttcaaaa attaccagaa aagctagttg
     6961 aaatactgtc cttctggtga ttttgcttaa tttctgatgt tcgagacatg attgaggaga
     7021 tttgtcttga ttttttccta aaaaagggca gactcctccc ttggtttgat gctcgatttt
     7081 taaaataagg tgacttattc tgttaggcat gtttccccct gccctctagc tctatatgga
     7141 acagggagta tcagatttat ctggcagatt gtatcaaata aggcttgaaa ctgttttgaa
     7201 taggcgtata gacttgagaa tttgagaata tgtcgtctag cagtagagac atattttccg
     7261 gcaatatgaa ggaagagacg tcgaaaacgc ttgatagtca aggcctttac ttcatcacca
     7321 gctagctgct ttaaaaagag gtagagatta taagccagac agcccatcat catacgtact
     7381 tcattcttaa tcatggtcga actatctgtc ttatccccaa agaatcctgc tttcctttct
     7441 ttgataaagt tttcagcatt ccctcgttca cgatagaatt gaaacagctc ctcactatct
     7501 acactgctta aattgttcaa atgaactttt ttacaaccat aaaaaagagc acttaatcgt
     7561 actcttctct tttaaggatt agttgaatta attcaaatcc actagttctc ctgtttctag
     7621 gtagactagg cgttcacaaa tgttagcaat gtaatcagcg aagcgttcca gatgccctat
     7681 gatataaagg tattgagttc cattgggaat tgaggtttct tggtctttca taagtccaat
     7741 gatttccttt gataaggcat aataatattg gtcaatctgt tcatcttttt gagcaatact
     7801 aatagctttt gaggcttggt gcaaaggaaa ggcaaccaat aaatcggcta gcatgctgag
     7861 ggataattta cccatttggt gtaactgttc ttcgtcaggg gctagttgat tttcttttag
     7921 ttgcaaaaca gctttggcaa tgcctgccat atggtctccc atacgttcaa ggtctgaaca
     7981 agaagacatg atgctaatca caaatcgaag gtcagacact tgtggctgct gcaaggccaa
     8041 caaacgggca caggtcaatt cgatagcgct ttgaccttgg ttgatagcat gatccttatt
     8101 gataattagc tctgccatct ccttgtcttt ggaggctaag gccagtaagg cttttgaagc
     8161 tgtttcaagg acaagttgcc ctagtcctaa aaaggattgt tctaattcat gcaattctaa
     8221 gtcaaattga tttctcatag gtttttcctt ccttatccga accgtcctga aatatagtct
     8281 tctgtgcgct gatcttttgg attggtaaac acgtcaacgg tatctccaaa ttcgcaaatt
     8341 tctcctgtta agaaaaaagc agttttatct gaaatacgtg aagcttgttg catgttatgg
     8401 gtaacaatga taatcgtata atcctttttt agttgctgaa tgaggtcttc aatttttaaa
     8461 gtggagatag ggtctaaggc tgaagtcggc tcatccatta acagaatatc aggttctact
     8521 gctaaagctc gcgcaatgca aaggcgttgc tgctgaccgc cagataagga catggcactc
     8581 tttttaagat catctttgac ttcttcccaa atggctgccc cttttaaaga tttctccact
     8641 aaggcatcta attgtttttt gtctcgaata ccatgtgtcc ttggaccata agccacgtta
     8701 tcatagatag acatggcaaa gggattaggc tgttgaaaaa ccatccctac acgcttgcgt
     8761 agctgattaa ggttgaattt gctactataa atatcttgct catctaagag gacttggcct
     8821 tcaatatggc aagaaggaac caaatcgttc atccgattaa gggtttttag aaaagttgat
     8881 ttgccacaac cagatgggcc tatcaaggca gtaatctgtc tttctggtaa ttgaatcgaa
     8941 atatttttta aggcttgaaa atccccgtaa aataagtcta ggtgtctaac tgaaaatgtt
     9001 cccatactag gaagctcctt tcacaagttt tcgagataat aagcttgata gagtatttat
     9061 cattaaaaca gtaataatca aaatcacacc ggtagcatag gcttcattga catgtagccc
     9121 ctcacttgac agcatataca tatgcagggc tagagaacga cctgaagaca tgagactact
     9181 tggcgtattg gtagaggtac ctaatgtata catgagggca gctgtctcac caacgatacg
     9241 gccaatagct agtatcactc cagctaaaat acctggcatg gcaactggta gaacaattct
     9301 aaaaacagtc cgtaacttac ctgccccaag tccataactt gcttgacgca tgctatcact
     9361 aacagataaa agggcttctt ctgttgagcg aataatgact ggcaacacca tgataactga
     9421 ggttaagatt cctgataaca gagagtattg aaaacctaag aagactacaa agaagagcat
     9481 gccaaacaga ccaaaaacaa tggaaggaat cccagacaag gtatctgagg ccaatcgcat
     9541 gattttaaca caaagggaat ctttttttgt atattccaca agataaaaac cagcaaaaat
     9601 ccctatgggc aaggctaaaa gaagagcacc aaagaccaga ataacggtgg aaataatcgc
     9661 tggcataagg gaaatgttct cagaagtata agtccaagaa aagagggata gacttagatg
     9721 aggtaagcct ttgatgagga taaaaccaat gattaaaaag agagagccaa aggttaaagc
     9781 tgaaaaacaa taaacgagaa gttttagcag gtatttactc ataagatgat tttcctttca
     9841 agtaggcaaa gtaggcatta atcaagagaa taaggaaaaa gagaactgct gaggttgcaa
     9901 taagggcttc cctatgctga cctgatgcgt aagccatttc cagaacaata ttggttgtta
     9961 aggttctggt tcctgaaaag agtccacttg gaataatcgg ctggttgcct gccaccaaaa
    10021 taactgccat ggtttcacct actgcgcgac cgattcctaa aataactgct gataaaatac
    10081 cagatctcgc agctggcaag atgacactaa aaatactccg ttcatgacta gctcctagag
    10141 ccaagctacc agaataatac gttttgggaa ctgttcggat agcagattct gacaaactga
    10201 taatggttgg caaaatcatt attcctaata gtaacgaagc ggttaggaca ctcatgccat
    10261 ttcctaaaaa gcttctaatc caaggcacca ataattgtag gccgaaaaaa ccataaacaa
    10321 tagatggaat ggccgccatc aagttgatag ctgattttaa gaagccatag acgggctttg
    10381 gacaataata aaccataaac accgatgtca agatgcctgt tggcacccca atcacaatcg
    10441 ctcctaaggt aattaataag gaaccaacga tcattggtaa aataccatag cttgccggaa
    10501 tgttcgttgg cgaccaatca ctgcctaata aaaaacgggc aaagccgtag ttagccatga
    10561 aaggtaagcc attactaaaa ataaagaaac agattagcaa aatagctaca acagctactg
    10621 ttgcactcat gaaaaaaatt gccctaaaaa ctgcttcttt gaaggcttgt tttatcacat
    10681 cttgtccttt ctagtgaaga aagtaaggga gatacgacac ctccctactt gccttcttta
    10741 tcttattgta cgatgaaacg tctgcatctc tttagagatt tatggagcaa acattttatt
    10801 taatcttgtc ccaggtggtt aatttgccac taaaaacgtc tgcaagttca gccatactga
    10861 cttggcttgc cttattgtca ttattgacca caacagcaat accgtctaaa gcaatagcat
    10921 catgggtgag actcttacct tcttcaggag ttaattccct agaaaccata ccaatatcag
    10981 cggttttctc cttaacagcg gtaatacctg ctgaagaccc attagaggta atatcaatcg
    11041 taacttctgg attttctttt ttataagctt ctgctaattt ttccattaaa gaagatactg
    11101 aagtggaacc tacaacagac aacttgcctg ataagtgttg gcttgtatat tctgtggttt
    11161 cggttttagc ttcaataaat ttattatctg tgaccacttg ttgaccttgt ttggagtgga
    11221 taaagctgat aaaatcttga cctagcttgg aaagattaga agaccaaaca atgttgaagg
    11281 gacgttgaag agggtattca ccatctaaaa ctgtgtctcg actagccttg acaccatcaa
    11341 tctctaaagc cttgacagat ttcgttaaag atcccaagga gatgtagccg atagcattag
    11401 cattcccttg aactgctgag agaacacctt ctgtactatt ttgaatcaca gctgttttgg
    11461 cagtgttgtc aattttttta tcaccgtctt ttttgagaat ccctgtgatt tctgtgaagg
    11521 caccccgtgt tccagagcca ttttctcgtg aaatcacctc aatcgttcct gaagctgact
    11581 gtttggaagc agctgactga ttgccacagg caacaagccc aaatcctgat aagccaatgg
    11641 ctgcaagagt aagcattttt ttgaatttca taataatcac ctttatctct atgtattttt
    11701 cttgtgtagg cttactacat ttatagtcta acaagtcttt gtaaaggttt atccctgatt
    11761 catgtaaaga ttgtgtaaag aatcaaaaaa agccactttt gaaaaatggc tgctcctaaa
    11821 aatagcttta aaaattatta gtcctgtgcg aaagattggt taggaagaaa aatcgtgaag
    11881 caactgcctc tgccaagctg actcgtcacc gtgacttggc cacctaataa ttgactgagt
    11941 tctttgacaa tggcaaggcc aagaccagtg ccaccagttt gtctgcttcg acctttatta
    12001 actcggtaaa aacgttcaaa aatacgatcc tgctctaatt gactaatacc aatccctgta
    12061 tctgatacag aaatcttaat gccttcgttc accttttggg tcttgacctc aattttcccc
    12121 ccttgttcag tgtaacggat ggcattggat aaaagattga gtaagatttg ggaaagtaat
    12181 tgactatctg atacgagggt gacatcatct ggcacctgca cctttagctg taaatccttc
    12241 ttcttgagct gaggttgcaa gctttgagtc aaatcctgta caaattctgc caaagaaagg
    12301 gtcgtccatt gtataggcat ttgttgagcc ttagataagg taagaagatg ctcaacaata
    12361 tgctcaagac gcaaactttc tttgtaaata atgtctagaa agtcatcctt gagcgcttct
    12421 tcttcagctg acatcccctt aatggtttca gcaaagccct taatcgaagt aactggtgtc
    12481 ctcaattcat gggaggcatt tgagacaaag gctaaattta acttttcata agttctaatc
    12541 gttgttaaat catatagcaa gacgagcaca gcttccacag attgggtggg gctaaaaacg
    12601 ggaactgctg tcacttctaa aatcaagtca ccctcatgaa acccacttac ttcttgtttt
    12661 aaccttgttt tttgatcaaa ggcttggtga actaaattcc gaatatccat ccgtttgagg
    12721 tcatcaagtg aacttatgtc gccgtccaca tcgggaaaat aatgaggcag agagcgactg
    12781 gataataaca tctgaccttg agcggaaact aaaaacgtcc ccatggttag gtgcgacaga
    12841 agaacctcca ttgtttcggc tagatccttg tattgctgat cctgttggga gactttggtt
    12901 tttaggccag acacatactg agccaaagac tttaagtctt cttgcccttt ttctaaaaag
    12961 tattcactac tggtcaagag aggttggtgc aaggtctcaa aagcaacttc ccatttccaa
    13021 aggcaaaaga gccagtagcc acctagtccc aaagaaaggg ctagaagaaa gagaccgatg
    13081 cctttactga tccaagttaa tgccatccct gcaatcagaa tgaggctaac acttagattg
    13141 actagccaaa attgaaggta gcgtttcatc tataactcct tgaacttata accataaccc
    13201 cgaatggttc gaataaattg aggggcttta ggattgtctt caattttttc cctcaactta
    13261 ccaatatgaa cgtccaccaa acgtgtttcc tgcccaaagt cataccccca gatacgttcc
    13321 aaaagacgct ctctagtcag tgtcatgttg ggatgtttca taagatagag caagagttca
    13381 aattcttttg gggtcaaact cagtaactta ttcgccttgt agacttcatg acgctcaggg
    13441 tatactttca aggtcccaaa tagccaagaa tcgtcagcga tattatctga atcatctcct
    13501 tcttgttctc ctttagttcg cctgaggaca gccttgacac gcgccagcaa ttctctaggg
    13561 ctaaaaggct tggtcaggta gtcatcagcc cctaattcca aggccaaaac cttatcaaat
    13621 tcatcacttt tcgcagaaac catcataatt ggagttttga cgcctttggc tctcagccgc
    13681 ttacaaactt ctatgccatc taattgtggt aacatgatat caagcaagat aaaatcaaag
    13741 ggttctgttt ctgccaaagc taaggccttc cgtccatttg tcaccaattg agtagaaaag
    13801 ccttccttac ttaaatggta gtcaagcaat ttcagaatgt gttcttcatc atccactaat
    13861 aagacttgtt ttgtcatcta ttatctccta ttggtaacat tataacacaa ttatcagaaa
    13921 tcctaacatt gctaaatcag attaaatttg cctatcaaga ctagtatctg gtcaaacgct
    13981 caatcatctc cttgtgctct ggataggtcg ccagtagatc taccctttca aataattcaa
    14041 aatcctcaaa ttcaaaacca ggagcaacaa gacaagaaac cagagcataa tccttatcaa
    14101 ctgttgatcc ccaaatagtg cccttaggaa cacagtagtg aagttgttgc cctttggata
    14161 tgtccaggcc taaagtgact gcttcgtagt gaccatctgc tgtaatcatg tgaacagtaa
    14221 gtggggatcc tgcatgaaaa taccagattt catctgctgt caatcggtga aaatgtgaag
    14281 gattcgtttc ttctaataag aaataaatac tggtataaag cgcccttccc ttaccagcaa
    14341 ggtttatagt gtctgaagct ttttttgttt gtctaaaata gccaccttca acatggggag
    14401 ctaactctag agttcttatc aagtcttctt tatccgtcgg agccaatggg ttgaagtaac
    14461 tcttgttcaa agtggtttta cgatttcaag aactcctctc agttctgagg acacggtaat
    14521 gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa agaattagcg aattattctg
    14581 gtaaaaaaaa tgccacgcta tgaaggctca agcgattgtc acaagtcaag ggagaattgt
    14641 ttctttggat atcgctgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag
    14701 aaatatcgga caagctggta aaatcttggc tgacagtggt tatcaagggc tcatgaagat
    14761 atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagccactaa cagttgaaga
    14821 taaagcctat aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
    14881 agtaaaaacg tttaaaatga tttcaacaac ctatcgaaat catcgtaaac acttcggatt
    14941 acgaatgaat ttgattgctg gcattatcaa tcatgaacta ggattctagt tttgcaggaa
    15001 gtctattatt tggttaggtg aattagtgaa gcgtttaggc aagtgtctct ggttacgacg
    15061 tcatggactc taaatcgatt atatttaggg gtcatgacta gtgaagcagt tagctagttc
    15121 gcatataagc ggctagcgtc taacaattag gaactttagt tccaataact ttaagattac
    15181 gacgttttag gacataaatc gatcatattt atgtcctaaa actagtgaag cgcctagcca
    15241 aagtccgaat aggatttggc gttagttact tagattgctt tgcaatcaag taactttggc
    15301 gatttacatc ttctctggcg cttctactcc aagcaagcga agggcttctt tgagaacgac
    15361 tgcggttgcg tagctgaggg ctagacggct gtcgcgttct gggctttcat ccaagatacg
    15421 tgtatgtgca tagtatttgt taaaggattg agccaggcta attgcaaatt tagcaatgat
    15481 agaaggttca aagttatctg ccgcacggtt gataatacgt gggaagtctt gaatgagttt
    15541 aatgatttcc cagctttcag tatcattcaa gctatagttg ccagctgttt ctggtttgaa
    15601 atcggctttg cgtaagatag attggatacg agcgtaggca tattgaacgt aaggtccagt
    15661 ttcaccctcg aaggatacca tagcctctag gtcgaagtcg tatccatttg tacggtcggt
    15721 tttgaggtca tagaatttaa tggctccaac cccaacagca tgtgctactt ggtctttgtt
    15781 ttctagttca ggatttttag cctcgatttg gaccttggca cggctaacag cctctgcaac
    15841 agtaggctct agcaagatga cattcccttt acgagtagag agcttcttcc cttcttttgt
    15901 aaccagacca aaaggaacgt gggtaatgtc gtcactccaa tcgtagccca tctcttgcaa
    15961 gacagctttg agttgtttaa agtgggcaga ttgctcttga ccaacgacgt agatagattt
    16021 agcaaattgg tattcatttt tacggtagag ggctgcagcc aagtcacgtg tgatatagag
    16081 agttgcacca tcagacttct tgatgagagc tggatgttca attccatatt tctcaagatt
    16141 cacaacttgg gcaccttctg attcaagaag tagtcctttt tcagaaagaa tgtctacaac
    16201 tgcatccatc ttatcattgt agaaggcttc tccgttatag ctgtcaaatt caaccttcaa
    16261 ttcattgtaa aggcggttaa attccactaa actttcatcg cggaaccatt gccaaagagc
    16321 gagagcttcc tcatctccat tttcaagttt acggaaccat tcgcgcgctt cttcatccaa
    16381 gctagggtca ttttcagctt cagcgttgat gcggacatag agtttaagga gttcatcgat
    16441 tggatgagct tttacagctt cttcgtcgcc ccatttttta taggcaacaa tcaacatccc
    16501 aaattgttta ccccagtctc ccaaatggtt gaccttgacc gtttgataac cgattttttg
    16561 gaaaatatgt gacaagctat ctccgataac agttgaacgc aggtggccaa tagaaaatgg
    16621 tttagcgata ttcggactag acatgtcgat aacaacattt tcttgtttac caatattttg
    16681 gtcagcatag tgttcttttt cagtggtaac agcttgcaat acttgagcag aaatggcaga
    16741 tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa aggcttggct
    16801 gttcattttt tcagccagtt cagccgcaat catttgtggt gctttacgtt cgacttttgc
    16861 aagagaaaaa gcagggaaag caatgtctcc catttctgag tttttagggg tttccagtaa
    16921 ctttaaaaca gcctcttggt ccaggctatc aatgatgcta gataattcgc tagcaatcaa
    16981 ttcttttata ttcattaaga gctccttttt ggacttttct actattttat cacaatttta
    17041 aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg gtataatatg gttataaata
    17101 tagttataaa tatgcacgca agaggatttt atgagaaaaa gagatcgtca tcagttaata
    17161 aaaaaaatga ttactgagga gaaattaagt acacaaaaag aaattcaaga tcggttggag
    17221 gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga aatcggcttg
    17281 accaaggtca agaaaaatga tatggtgtat tatgtactag taaatgagac agaaaagatt
    17341 gatttggtgg aatttttgtc tcatcattta gaaggtgttg caagagcaga gtttaccttg
    17401 gtgcttcata ccaaattggg agaagcctct gttttggcaa atattgtaga tgtaaacaag
    17461 gatgaatgga ttttaggaac agttgctggt gccaatacct tattggttat ttgtcgagat
    17521 cagcacgttg ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga taagtaaggt
    17581 cttgggagtt gctctcaaga cttatttttg aaaaggagag acagaaaatg gcgatagaaa
    17641 agctatcacc cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca gatgcttttt
    17701 tgctctttcg gatgggtgat ttttatgaat tattttatga ggatgcggtc aatgctgcgc
    17761 agattctgga aatttcctta acgagtcgca acaagaatgc cgacaatccg atccctatgg
    17821 cgggtgttcc ctatcattct gcccaacagt atatcgatgt cttgattgag cagggttata
    17881 aggtggctat cgcagagcag atggaagatc ctaaacaagc agttggggtt gttaaacgag
    17941 aggttgttca ggtcattacg ccagggacag tggtcgatag cagtaagccg gacagtcaga
    18001 ataatttttt ggtttccata gactgcgaag gcaatcaatt tggcctagct tatatggatt
    18061 tggtgacggg tgacttttat gtgacaggtc ttttggattt cacgctggtt tgtggggaaa
    18121 tccgtaacct caaggctcga gaagtggtgt tgggttatga cttgtctgag gaagaagaac
    18181 aaatcctcag ccgccagatg aatctggtac tctcttatga aaaagaaagc tttgaagacc
    18241 ttcatttatt ggatttgcga ttggcaacgg tggagcaaac ggcatctagt aagctgctcc
    18301 agtatgttca tcggactcag atgagggaat tgaaccacct caaacctgtt atccgctacg
    18361 aaattaagga tttcttgcag atggattatg cgaccaaggc tagtctggat ttggttgaga
    18421 atgctcgctc aggtaagaaa caaggcagtc ttttctggct tttggatgaa accaaaacgg
    18481 ctatggggat gcgtctcttg cgttcttgga ttcatcgccc cttgattgat aaggaacgaa
    18541 tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca tttctttgag cgtagtgact
    18601 tgacagacag tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt gtttcttttg
    18661 gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac cttgtctagt gtgccacgga
    18721 ttcgtgcgat tttagaaggg atggagcaac ctactctagc ctatctcatc gcacaactgg
    18781 atgcaatccc tgagttggag agtttgatta gcgcagcgat tgctcctgaa gctcctcatg
    18841 tgattacaga tgggggaatt atccggactg gatttgatga gactttagac aagtatcgtt
    18901 gcgttctcag agaagggact agctggattg ctgagattga ggctaaggag cgagaaaact
    18961 ctggtatcag cacgctcaag attgactaca ataaaaagga tggctactat tttcatgtga
    19021 ccaattcgca actaggaaat gtgccagccc actttttccg caaggcgacg ctgaaaaact
    19081 cagaacgctt tggaaccgaa gaattagccc gtatcgaggg agatatgctt gaggcgcgtg
    19141 agaagtcagc caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag gtcggcaagt
    19201 acatccagcg tttacaagct ctagcccaag gaattgcgac ggttgatgtc ttacagagtc
    19261 tggcggttgt ggctgaaacc cagcatttga ttcgacctga gtttggtgac gattcacaaa
    19321 ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct cagacctata
    19381 ttccaaatac gattcagatg gcagaagata ccagtattca actggttaca gggccaaaca
    19441 tgagtgggaa gtctacctat atgcgtcagt tagccatgac ggcggttatg gcccagctgg
    19501 gttcctatgt tcctgctgaa agcgcccatt taccgatttt tgatgcgatt tttacccgta
    19561 tcggagcagc agatgacttg gtttcgggtc agtcaacctt tatggtggag atgatggagg
    19621 ccaataatgc catttcgcat gcgaccaaga actctctcat tctctttgat gaattgggac
    19681 gtggaactgc aacttatgac gggatggctc ttgctcagtc catcatcgaa tatatccatg
    19741 agcacatcgg agctaagacc ctctttgcga cccactacca tgagttgact agtctggagt
    19801 ctagtttaca acacttggtc aatgtccacg tggcaacttt ggagcaggat gggcaggtca
    19861 ccttccttca caagattgaa ccgggaccag ctgataaatc ctacggtatc catgttgcca
    19921 agattgctgg cttgccagca gaccttttag caagggcgga taagattttg actcagctag
    19981 agaatcaagg aacagagagt cctcctccca tgagacaaac tagtgctgtc actgaacaga
    20041 tttcactctt tgatagggca gaagagcatc ctatcctagc agaattagct aaactggatg
    20101 tgtataatat gacacctatg caggttatga atgtcttagt agagttaaaa cagaaactat
    20161 aaaaccaaga ctcactagtt aatctagctg tatcaaggag acttctttga caattctcca
    20221 cttttttgct agaataacat cacacaaaca gaatgaaaag gagctgacgc attgtcgctc
    20281 ccttttgtct attttttaag gagaaagtat gctgattcag aaaataaaaa cctacaagtg
    20341 gcaggccttg gcttcgctcc tgatgacagg cttgatggtt gctagttcac ttctgcaacc
    20401 gcgttatctg caggaagtat tagacgccct ccttactggg aaatatgaag ctatttatag
    20461 tatcggggct tggttgattg gtgtggccgt agtcggtcta gttgctggtg gactcaatgt
    20521 tgtcctcgca gcctatattg cccaaggagt ttcatccgac cttcgggagg atgccttccg
    20581 taaaattcaa accttttctt atgctgatat tgaacaattt aatgcgggaa atctagtcgt
    20641 tcgaatgaca aatgatatca accagattca gaacgttgtc atgatgacct tccaaattct
    20701 tttcagactt cccctcttgt tcatcggttc gtttatccta gcggttcaaa ccttaccttc
    20761 tctgtggtgg gtgattgttc tcatggtagt cttgattttt ggtttgactg ctgtcatgat
    20821 gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt cttgagcgca tcaatgccat
    20881 tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag aaaaagagca
    20941 atttgctaag tttacagagg tctcagacga gctttttggt caaaaccttt acattggtta
    21001 tgccttttca gtagtggaac cctttatgat gttggttggt tacggggcgg tcttcctctc
    21061 tatttggctg gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt ccatcgcttc
    21121 ttttgttaat tacctaagcc agattatctt taccattgtt atggttggat ttttgggaaa
    21181 ttctgtcagc cgtgccatga tttccatgcg tcgtattcga gaaattcttg acgcagagcc
    21241 agctatgacc ttcaaggata tcccagatga agagttggtt ggaagcctta gctttgaaaa
    21301 tgtgaccttt acctatccaa tggacaagga accgatgctg aaagatgtga gctttactat
    21361 tgaacctggt caaatggttg gtgtagttgg agcgactggt gcaggaaagt caaccttggc
    21421 tcaattgatt ccacgtctct ttgatccaca gaacggggcc attaaaatcg gtggcaagga
    21481 tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc tccaacgtgc
    21541 cattcttttt agtggaacga ttgcagataa cttgagacag gggaagggaa atgctactct
    21601 atttgaaatg gagcgcgcag ccaatattgc ccaggctagt gaattcattc atcgtatgga
    21661 gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat ttctctggtg gacaaaaaca
    21721 aaggatgtcg attgcgcgtg ggattgtcag caatccacgt attctgattt ttgacgattc
    21781 gacctcagcc ttggatgcca aatcagagcg cttggtgcaa gaagctttga ataaggactt
    21841 gaaggggacg acaaccatta ttattgctca aaaaattagc tcggttgtcc atgcagacaa
    21901 gatcttggtt ctaaatcaag gacgattgat tggtcaaggc acgcatgcag acttggttgc
    21961 caacaatgcc gtttaccgtg aaatctatga aacacagaaa tgaaagacaa actataagaa
    22021 aagtcaatag ttttatctaa attatttctt atttcaattt gatgatttgg cgatgatttt
    22081 agagcacggc aaaaagccct tgaaaaagtc cattttttca aaggtaatcc tgtgtt
//
LOCUS       DBEJNA010000037        21030 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEJNA010000037 DBEJNA010000000
VERSION     DBEJNA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.37"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            119..616
                     /locus_tag="ACL3JB_001656"
     CDS             119..616
                     /locus_tag="ACL3JB_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0686354.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            616..2271
                     /gene="dnaX"
                     /locus_tag="ACL3JB_001657"
     CDS             616..2271
                     /gene="dnaX"
                     /locus_tag="ACL3JB_001657"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0686355.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PALSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2299..2493
                     /locus_tag="ACL3JB_001658"
     CDS             2299..2493
                     /locus_tag="ACL3JB_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0686356.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2643..3413
                     /gene="sufC"
                     /locus_tag="ACL3JB_001659"
     CDS             2643..3413
                     /gene="sufC"
                     /locus_tag="ACL3JB_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0686357.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3441..4703
                     /gene="sufD"
                     /locus_tag="ACL3JB_001660"
     CDS             3441..4703
                     /gene="sufD"
                     /locus_tag="ACL3JB_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0686358.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFY
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4714..5940
                     /locus_tag="ACL3JB_001661"
     CDS             4714..5940
                     /locus_tag="ACL3JB_001661"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0686359.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5927..6367
                     /gene="sufU"
                     /locus_tag="ACL3JB_001662"
     CDS             5927..6367
                     /gene="sufU"
                     /locus_tag="ACL3JB_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0686360.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6417..7829
                     /gene="sufB"
                     /locus_tag="ACL3JB_001663"
     CDS             6417..7829
                     /gene="sufB"
                     /locus_tag="ACL3JB_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0686361.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8060..9301)
                     /gene="pbp3"
                     /locus_tag="ACL3JB_001664"
     CDS             complement(8060..9301)
                     /gene="pbp3"
                     /locus_tag="ACL3JB_001664"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0686362.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9404..10513
                     /gene="cozE"
                     /locus_tag="ACL3JB_001665"
     CDS             9404..10513
                     /gene="cozE"
                     /locus_tag="ACL3JB_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0686363.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11159..11506
                     /gene="ssrA"
                     /locus_tag="ACL3JB_001666"
     tmRNA           11159..11506
                     /gene="ssrA"
                     /locus_tag="ACL3JB_001666"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11678..11765)
                     /locus_tag="ACL3JB_001667"
     tRNA            complement(11678..11765)
                     /locus_tag="ACL3JB_001667"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11729..11731),aa:Ser,seq:gga)
     gene            11927..12667
                     /locus_tag="ACL3JB_001668"
     CDS             11927..12667
                     /locus_tag="ACL3JB_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0686364.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAVSLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12664..13575
                     /gene="pfkB"
                     /locus_tag="ACL3JB_001669"
     CDS             12664..13575
                     /gene="pfkB"
                     /locus_tag="ACL3JB_001669"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0686365.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVELVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            13572..15524
                     /locus_tag="ACL3JB_001670"
     CDS             13572..15524
                     /locus_tag="ACL3JB_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0686366.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGSLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15661..17913
                     /locus_tag="ACL3JB_001671"
     CDS             15661..17913
                     /locus_tag="ACL3JB_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0686367.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILSQAELKFPEQEDDSDDEDVQVDFSAK
                     EALKYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(17956..18387)
                     /locus_tag="ACL3JB_001672"
     CDS             complement(17956..18387)
                     /locus_tag="ACL3JB_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0686368.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            18525..19667
                     /locus_tag="ACL3JB_001673"
     CDS             18525..19667
                     /locus_tag="ACL3JB_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0686369.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKIDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19676..20890
                     /gene="thiI"
                     /locus_tag="ACL3JB_001674"
     CDS             19676..20890
                     /gene="thiI"
                     /locus_tag="ACL3JB_001674"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0686370.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
BASE COUNT         6167 a         3896 c         4659 g         6308 t
ORIGIN      
        1 gctccataat atctataagg gatttaccca ctacaaatat tatagagccc aaaatccttt
       61 gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata atagttctat
      121 gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt ccttcctatt
      181 ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctta taaaatcacg
      241 ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat tggttttagg
      301 tcccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg tttgtggtga
      361 ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc tcaactatat
      421 ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga atggtcagtt
      481 acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta tggatcgaga
      541 ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact ttacgatgtt
      601 tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca aaacttctcc
      661 cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga gcaagagaaa
      721 ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag tgttgctaaa
      781 atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg caataactgc
      841 tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat ggatgcagct
      901 tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta tgcacctagc
      961 cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac aggggctttt
     1021 aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat tttggccact
     1081 actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt tgagtttaaa
     1141 tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa agaaaatatc
     1201 agttctgaac cagaggctgt ggaaatcatt gccagacggg cggaaggtgg aatgcgggac
     1261 gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct gacgactgct
     1321 atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta tgtggcggcc
     1381 ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt tgacaatggt
     1441 aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt gttaattgtt
     1501 caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt ggcacttcct
     1561 caaaaaaatc tgtttgaaat gattcgctta gcaacagtga gtttagcaga tattaagtct
     1621 agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga aatcaagccc
     1681 gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca ggaagttgcc
     1741 cgtctcaaac aagagctttc taatgtaggt gcggttccta aacaagttgc accagctctt
     1801 agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt gcaatctatc
     1861 ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atttaattcg tttgcagaat
     1921 gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct agctggttct
     1981 caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa cttcaatgct
     2041 ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct cagtcaggcg
     2101 gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga agttcgcgca
     2161 gccttttcag ccaaagccaa atcttctcaa actgaaaaag aagtagaaga aagcctgatt
     2221 ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta aagaaagatt
     2281 tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct gtttacagct
     2341 gctgagacct attttttcaa tgaagcctgg atgactggcc gctatattat ggcagccttt
     2401 tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggcaa aatcgttgat
     2461 gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca aaatcaaagc
     2521 cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt gctctatttc
     2581 tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag aaaggaacta
     2641 tcatgtcagt attagagatc aaagatcttc acgttgagat tgaaggaaaa gaaattttaa
     2701 aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga ccaaatggta
     2761 caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa gtaactaaag
     2821 gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag cgtgcgcgta
     2881 tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc aatgctgagt
     2941 ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca gttcgtgagt
     3001 ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa atggcagagc
     3061 gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt cttcaacttt
     3121 tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt gatattgacg
     3181 ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt ggtgctatga
     3241 tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta cacgtgatga
     3301 tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg gaacgtgaag
     3361 gatacgcaaa attagctgaa gaacttggct acgactacaa ggaagaattg taatttcctc
     3421 gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca gaaatgcacg
     3481 ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt gagactttgg
     3541 aattaccagt tattgagcgt gtcaaattct accgttggaa tctgggtgat ggaacgatta
     3601 cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat cacttgaagt
     3661 tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta gctgaacagg
     3721 gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg atcgaagaat
     3781 tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac acagcttact
     3841 ttaacagtgg tgctgtactc tatattccag ataatgtaga aattacagag ccaattgaag
     3901 gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt atgattatcg
     3961 ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt gaaggaagtg
     4021 acaaagcaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg caagtcaagt
     4081 ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt cgtggtaaat
     4141 taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga aatgtcgttg
     4201 ctgattttga tagtgacttg attggtaatg gtagccatgc tgacctcaag gttgtagctc
     4261 tttcaagtgg tcgtcaggta caagggattg atactcgtgt aactaactat ggctgcaact
     4321 caatcggaaa cattctacaa catggggtta tccttgaaaa agcaactttg actttcaatg
     4381 gtatcggcca catcatcaag ggtgctaagg gagcagatgc gcaacaagag agccgtgttc
     4441 tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt gatgaaaatg
     4501 acgtaactgc aggacatgca gcctctattg gtcaggtaga tccagaagac atgtattacc
     4561 tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt ggtttccttg
     4621 gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt gcaactatcg
     4681 aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc gattcgcaag
     4741 gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct ggacaatgct
     4801 gcgacgacac aaaaaccact agtagttctg aaagctatta acagctacta tgagcaggac
     4861 aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc ttcttatgaa
     4921 gctgctcgtg aaaccattcg taagtttatt aatgcaggct ctacaaagga agttctcttt
     4981 accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga aattctcact
     5041 gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat tccatggcag
     5101 gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga cggtgccttg
     5161 gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc cctagctcat
     5221 gcctccaatg ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt agcccaccaa
     5281 gttggggcaa tcatggtagt ggatggtgct caatctacac ctcatatgaa gattgatgtc
     5341 caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg tccgactggt
     5401 atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt agaatttggc
     5461 ggcgagatga ttgattttgt ctacgagcaa tctgctagtt ggaaggaatt gccttggaaa
     5521 tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc agttgattat
     5581 ctggaaaaga ttggtatgga tgccattgaa gctcatgaac aggaattgat tgcgtacgtc
     5641 tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga tttggctcaa
     5701 cgttcgggtg ttattgcctt taacctaggt gatctccatc ctcacgatct tgcgacggct
     5761 ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc cttgcttcag
     5821 tatttggaag tcccagcaac agctcgtgca agtttttata tctacaatac caaggcagat
     5881 tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg cactttctaa
     5941 actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac atcaccaagg
     6001 gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtgggg atgtcatcaa
     6061 cctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc taaattcagg
     6121 atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag gaaaaaccaa
     6181 acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc aaaaagatga
     6241 gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat tccctcaaag
     6301 aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa atcaagaaaa
     6361 acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag gatattatgg
     6421 ctgaagaaag agtagaacca aaaccaattg accttggtga atataaattt ggtttccatg
     6481 acgatgtaga gcctgtctta tcgacaggaa aaggactcaa cgaaggtgtt attcgtgaat
     6541 tatctgctgc taagggtgag cctgagtgga tgttggagtt ccgtttgaag tcttatgaaa
     6601 ccttcaaaaa aatgcccatg caaacttggg gagcagactt gtcagagatt gactttgatg
     6661 acttaatcta ctaccaaaaa ccatctgaca aaccagcccg ttcttgggat gatgtacctg
     6721 aaaagattaa agaaaccttt gaacgtatcg ggattccaga agctgaacgt gcttatttag
     6781 caggggcttc tgcccagtac gagtcagaag tggtttacca caacatgaag gaagagttcc
     6841 aaaaattagg tattatcttt acagatacag attccgcact caaggaatac ccagacttat
     6901 ttaaacaata ctttgcgaag ttggtaccgc cgacagataa caagttggca gccctcaact
     6961 cagcagtatg gtcgggtgga acttttatct acgtgccaaa aggtgtcaag gtagatattc
     7021 cacttcaaac ttatttccgt atcaataacg aaaatatagg tcagttcgaa cgtaccttga
     7081 ttatcgttga tgagggagca agcgtccact acgtagaagg atgtacagca ccaacatatt
     7141 caagcaatag cttacacgct gccattgtag aaatttttgc tttggacgga gcttatatgc
     7201 gttatacaac tatccaaaac tggtctgata acgtctataa cttggtaaca aagcgtgcta
     7261 aggctcaaaa ggatgccact gttgagtgga ttgatggaaa cttgggtgcc aaaacgacta
     7321 tgaaatatcc atctgtttac cttgatggag aaggagcgcg tggtaccatg ctctctatcg
     7381 cctttgctaa tgcagggcaa caccaagaca cgggtgctaa gatgattcac aatgctccac
     7441 ataccagctc gtctattgtg tctaaatcca tcgctaaagg tggaggaaag gttgactacc
     7501 gtggacaagt cacctttaac aagaactcta agaaatctgt ttcccacatt gaatgtgata
     7561 ccattatcat ggatgacttg tcagcatcag atactattcc atttaatgaa attcacaact
     7621 cgcaagtggc tttggaacac gaagccaaag tatctaagat ttcagaagag caattgtatt
     7681 atctcatgag ccgtggattg tcagaatctg aggcaactga aatgattgtc atgggatttg
     7741 tagaaccctt tacaaaagaa cttccaatgg aatacgcagt tgagctgaac cgcttgatta
     7801 gctatgaaat ggagggatca gttggataaa atttgatttt atactcttcg aaaatctctt
     7861 caaaccacgt cagcatcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta
     7921 caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgt tctttgattt
     7981 tgagtattag atttactcaa aatcaaggat tttgaagatg aacttgtatc aaaaaatcgc
     8041 ggtttaaaat cgcgattttt tataatttct cgttaacaaa gcggacaaac tgattccacc
     8101 aaacttttaa gaagaaggct ttttcaattt tcttgtctgc taccatttcg aaactagggc
     8161 gctctgtggt gatgtaacct tgaccaatca agttcttgtc ttcataagtc aaatggccaa
     8221 ccactgttcc agcttcaagt ggtgctggga ttgctttgga atcaggtgtg aattgaacag
     8281 attgggaaga ttgattccca acacgttcta ttagatagat atcctctgga gccactgcag
     8341 ttactgtatc ttcttttcca tcttgtacag gggctttgct atcttgatag gcatcgcctt
     8401 gttgaacgat tttgcgaagt gtaaatgtag aagaaatata atccattagg gaagatgtag
     8461 ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc atttaaaaca actgtgatga
     8521 ctctcatgcc tttttcgaca gtagtaccaa caaaagactc tccagcctta tctgttgttc
     8581 ctgtttttag cccatcaaaa ccaccacggt aagcaggcat accttctaac atgtagttgg
     8641 ttgaagtgat tgtcatccca gcaaaagtag aagaaggttt tttggtgatt tctaagactt
     8701 gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac atcataagca ctaagcttat
     8761 tttcctcatc ttttttagaa cctgggtaaa tgttatcccc tagagtttca ttgttaagac
     8821 ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc caagagtttt gcccgcatca
     8881 tatcgacgaa atctttttct gagccagcaa ttttctcagc tagggcaata gcggcgctgt
     8941 tggcactaga taccagagtt gcttcaagca actcttcgac agtataatta cgggcctcca
     9001 taggaatatt actggcttca gaatttgtcg tcaattgata aggataatca gaaatatcta
     9061 caggagtgga gagggtaata cttccgtttt ccaaagcttc atagaccaga taaacagtaa
     9121 tcaattttgt tatggaagca atttcgacag gttgcgttgc atccttctca tagagaattt
     9181 taccagtatt tgcctcaaca gcaatcgcat gtttagcggc aatggtaaaa tcttgagcaa
     9241 cagcagtaga agcaccccct aaaagagaga cagttaacaa agttaaaaat atttttttca
     9301 tagtagtttt attctatcat aaagaaaaaa aatattcttg ctttaataat tcatctgtta
     9361 agctttttga aaatatggta aaataaagtg agggaggtaa ctcatgtttc gtagaaataa
     9421 attatttttt tggaccacag aaattttact cttaaccatc atcttttacc tatggagaca
     9481 gatggggtct ttgattaacc cttttgttag cgtgcttaat acaattatga ttccattttt
     9541 attagggggc tttctttatt atttgacaaa ccctattgtt actttcttaa ataaagtctg
     9601 taaactcaat cgtttgcttg gtattttaat taccttgtgt actttggtct ggggaatggt
     9661 cataggtgtt gtctatctct tacctatttt gattaatcag ttatctagtt tgattatatc
     9721 tagtcaaact atttatagtc gagtacaaga cttaatcata gacttatcta attatcctgc
     9781 gctccagaat ttggatgtag aagctacaat tcagcagtta aacttatcct atgttgatat
     9841 tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg agcgtcttgt cagctcttat
     9901 cagtactgtt ttgattttga ttatgactcc agtttttttg gtttatttct tattagatgg
     9961 acataaattc ttgcccatgc ttgaaagaac gattctaaag agggatcgct tgcatattgc
    10021 aggcttatta aagaatttaa atgcgacgat tgctcgctat attagtggag tttcgattga
    10081 cgcaatcatt ataggttgtt tggcttatat tggctatagt attattggtt taaaatatgc
    10141 tttagttttt gccatttttt ctggtgtagc caatttaatt ccttatgtgg ggccaagtat
    10201 tggtttgatt cctatgatca tcgcaaatat attcactgat ccccatagac tgctgattgc
    10261 agtgatttat atgcttgttg ttcagcaggt agatggcaat atcttatatc ctcgaatcgt
    10321 aggaagtgtt atgaaggttc atccaatcac gattttagtt ttacttttgt tgtcaagcaa
    10381 tatctatggt gtagttggaa tgattgtcgc agtgccaacc tattctatct tgaaagaaat
    10441 ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata atgaaagaac gagaaagaga
    10501 attagctaag taaaagtcag gagaaccctg atttttcttt actggaagtg gcctttagat
    10561 tagaagactg aaaataagtt aaagtcttaa actaattttc acagctaaga atagtagaag
    10621 ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg tcagggtaag ttccactggt
    10681 tttcatagtc tattaaagtt cgaatgaaac ctatttatag tatattgaaa ctagaatagt
    10741 acacctctaa ttctaaaaca ttgttagaaa tcgatttgac tgtcctaatc tattcgtcct
    10801 attcttattt cattttacta tattttggtg caataagtga aaagtagtcc gaataatata
    10861 aggattgatt ttatagtttt taaactcaaa tgaattaaaa taaagagagt acgaaaattc
    10921 tcatctgaaa gtattttaga ataattctct tcgtgaattt cttcaaaaca gatagcttca
    10981 tcttaggtat gtgttaattg gatttcgtaa gctctattta caatcgtaaa gttatgcact
    11041 gagaaagttg tagttagtct tccagtttgc taaatttttc gaatagtatc ttttttaggt
    11101 atgtgatttc tttttgcatt tttgagttag ataaggtata atggttttat tgtcttttgg
    11161 ggtcgttacg gattcgacag gcattatgag gcatattttg cgactcgtgt ggcgacgtaa
    11221 acgctcagtt aaatataact gcaaaaaata acacttctta cgctctagct gcttaaaaac
    11281 cagcaggcgt gacccgattt ggattgctcg tgttcaatga caggtcttat tattagcgag
    11341 atacgattaa gccttgtcta gcggcttgat aagagattga tagactcgca gtttctagac
    11401 ttgagttatg tgtcgagggg ctgttaaaat aatacataac ctatggttgt agacaaatat
    11461 gttggcaggt gtttggacgt gggttcgact cccaccggct ccattattcc tttgcattcc
    11521 ttggtaaaac gttgttaaat caacgttttt tatttttatc tttggtattc ctttgcattc
    11581 ttttgctaaa aagggagtca caaacagacc ctattttaaa aaaggataga aaaaaggata
    11641 caacatttgt cgcatcctaa aaataatctt ttttccacgg aagacatggg attcgaaccc
    11701 acgcacgcta ttacacgcct accgcgtttc caacacggcc tcttaagcct cttgagtaat
    11761 cttccaatac ttactcaaat agtctaccat aaaggctctt atcttgcaat aaaaattcta
    11821 gaaataagaa aaatgataga ttttgaaaga aaatgataaa aaatgcttga cttcaaaaga
    11881 aagtatgata gaatgaatag tgtaaacgat aacaggaggt gattcggtgt taaaaacaga
    11941 gcggaagcaa ctgattttag aggagttaaa tcaacatcat gtagtttctc tagaaaaatt
    12001 agttagtttg ctagaaacgt cagaatcaac ggttcgaaga gacttggatg agttggaagc
    12061 ggaaaacaag cttcgtcgtg tgcatggtgg agcagaactc ccccactcct tacaggaaga
    12121 agaaaccatt caagaaaaat ctgtcaaaaa ccttcaagaa aagaagttgc tggctcagaa
    12181 agcagtctct ctcattaaag aaaaagatgt catctttatc gatgctggaa caacaactgc
    12241 ttttttgatt catgaattgg tcaataagaa tgttacagtt gtgaccaact ccattcacca
    12301 tgccgctcag ttggttgaaa agcagattcc aactgtcatg gttggaggaa acgtcaagac
    12361 ggcgacagat gctagtatcg ggggcgttgc tcttaaccag attaaccaat tgcactttga
    12421 ccgtgccttt atcggaatga atggtgttga cgatggctat tatacgactc ctgatatgga
    12481 ggagggagct gtgaaaagag ctattttgga gaatgccaag cagacctacg tcttggtgga
    12541 ttcgtcaaaa attggacaaa cttgctttgc caaggtagcc ccactcaaac gcgctatcgt
    12601 tatcactagt caagggcatg agctcttgca ggttattaag gagaaaacgg aggtaataga
    12661 agtatgattt atacagtcac actcaatcca tccattgact atatcgttcg tttggaccaa
    12721 gtcaaagttg gtagtgtaaa tcgtatggac agtgatgata agtttgctgg tgggaaagga
    12781 atcaatgtca gccgtgtctt gaaacgtttg aatataccaa atacagcgac gggatttatc
    12841 ggtggcttta ctggtaaatt tatcacagat actttagcag aggaagaaat cgagacacgt
    12901 tttgtccagg tggcagaaga tactcgtatc aatgttaaaa ttaaagcaga ccaagaaaca
    12961 gaaatcaacg gaacgggtcc aactgttgaa ctggttcagc tagaagaatt gaaagctatt
    13021 ttatctagtc tgacagcaga agatacagtt gtctttgcag gttcaagtgc taaaaatcta
    13081 ggtaatgtta tctataagga tttgatttcc ttgacgcgcc agactggtgc gcaagtggtc
    13141 tgtgactttg aaggacagac cttaattgat agtttggact accagcctct tcttgtaaaa
    13201 ccaaacaatc atgaacttgg agcgattttt ggggttaaac tcgaaagttt agatgaaatt
    13261 gagaaatacg ctcgtgagtt actggctaag ggtgctcaaa atgttattat ctctatggct
    13321 ggggacggtg ctcttcttgt cacatctgag ggagcttact ttgctaaacc aatcaaagga
    13381 acagtcaaaa attcagttgg ggctggtgat tctatggttg ctggattcac aggtgaattt
    13441 gtcaaatcaa aagacgcagt agaagccttc aaatggggag tggcttgcgg aacggcaact
    13501 accttctcag atgacttggc aacggcagaa cttattaaag aaacatatgg aaaagttgag
    13561 gtagaaaaac gatgaaaatt caagacctat tgagaaaaga tgtcatgttg ctagatttgc
    13621 aggcaactga aaaaacagct gtcatcgacg agatgattaa aaatttgaca gaccacggtt
    13681 atgtaacaga ttttgaaaca tttaaagaag gaattttggc gcgtgaagct ttgacttcta
    13741 ctggtttggg tgatggaatc gcaatgcctc acagcaaaaa cgctgctgtc aaagaagcga
    13801 cagttctatt tgctaagtca aataagggtg ttgactacga gagcttggat ggacaagcaa
    13861 ctgacctctt cttcatgatt gcagctccag aaggtgccaa tgatactcac ttggcagcct
    13921 tggcagaatt gtctcaatac ttgatgaaag acggttttgc agacaaactt cgtcaagcaa
    13981 catctgcaga ccaagttatc gaactttttg accaagcttc agaaaaaact gaggaacttg
    14041 ttcaagcacc tgctaatgac tctggtgact ttatcgtagc tgttacagct tgtacaacag
    14101 gtattgccca cacttacatg gcccaagaag cccttcaaaa agtagctgct gaaatggggg
    14161 ttggtatcaa ggtcgaaacc aacggtgcta gcggtgttgg aaatcaacta actgcagaag
    14221 atatccgtaa ggctaaagct attatcattg cagcagacaa ggccgttgaa atggatcgat
    14281 ttgatggaaa accattgatc aatcgtccag ttgctgacgg tatccgtaag acagaagagc
    14341 taattaactt ggctctttca ggagatactg aagtctaccg tgccgctaat ggtgcaaaag
    14401 ctgcaacagc ctctaacgaa aaacaaagcc ttggtggtgc cttctacaaa cacttgatga
    14461 gtggtgtatc tcaaatgtta ccattcgtta tcggtggtgg tatcatgatt gcccttgcct
    14521 tcttgattga cggtgctttg agtgttccaa atgaaaacct tggcaatctt ggttcttacc
    14581 atgagttagc ttctatgttc atgaaaattg gtggagctgc ctttggtttg atgcttccag
    14641 tctttgcggg ttatgttgcc tactctattg ctgaaaaacc aggtttggta gcaggtttcg
    14701 tggctggtgc tattgccaaa gaaggttttg cctttggtaa aattccttat gccgcaggtg
    14761 gtgaagcaac ttcaactctt gcaggtgtct catctggttt cctaggtgcc cttgttggtg
    14821 gatttatcgc aggtgccttg gttcttgcca tcaagaaata cgttaaagtt cctcgttcac
    14881 tcgaaggtgc taaatcaatc cttctattgc cacttcttgg aacaatcttg acaggatttg
    14941 ttatgttagc tgtgaatatc ccaatggctg caatcaacac tgctatgaat gacttcctag
    15001 gcagtcttgg aggaggttca gctgtccttc ttggtatcgt ccttggtgga atgatggctg
    15061 ttgacatggg tggaccagtt aataaagcag cttatgtctt tggtacaggt acgcttgcag
    15121 caactgtttc ttcaggtggt tctgtagcca tggcagcagt tatggctgga ggaatggtgc
    15181 caccacttgc aatatttgtc gcaactcttc ttttcaaaga taaatttact aaggaagaac
    15241 gtaactctgg tttgacaaac atcatcatgg gcttgtcatt tatcactgag ggagcgattc
    15301 catttggtgc cgctgaccca gctcgtgcga ttccaagctt catccttggt tcagcagtag
    15361 caggtggact cgttggtctt actggtatca aactcatggc gccacacgga ggaatcttcg
    15421 ttatcgccct tacttcaaat gctctccttt acctcgtttc tgtcttggta ggagcaatcg
    15481 taagtggtgt ggtttatggt tacctacgca aaccacaagc ataaaaaata gaaaaatgaa
    15541 aagattggac cgtttggtgc agtctttttc tcttcccgaa atgcctgtga aatatggtat
    15601 aatagaagaa tggcaaacaa gaatacaagt acaacaagac ggagaccgtc taaagcagaa
    15661 ctggaaagaa aagaagcgat tcaacgaatg ttgatttcgt taggaattgc gattttattg
    15721 attttcgcag ccttcaaatt aggggctgca ggtataaccc tttataattt aattcgcttg
    15781 ctagtgggta gcctagctta tctggcgata ttcggcctat taatctatct cttctttttc
    15841 aagtggatac gaaaacagga aggactctta tctggctttt tcaccatatt tgctggctta
    15901 ctcttgattt ttgaggccta cttggtttgg aaatatggtt tggacaagtc cgttctaaaa
    15961 gggaccatgg ctcaggttgt gacagatctg actggttttc gaacgactag ctttgctgga
    16021 gggggcttga tcggggtcgc tctttatatt ccaacagcct ttctcttttc aaatatcgga
    16081 acttacttta ttggttctat cttgatttta gtgggttctc tcctagtcag cccttggtct
    16141 gtttacgata ttgctgaatt tttcagtaga ggctttgcca aatggtggga agggcacgag
    16201 cgtcgaaaag aggaacgctt tgtcaaacaa gaagaaaaag ctcgccaaaa ggctgagaaa
    16261 gaggctagat tagaacaaga agagactgaa aaagccttac tcgatttgcc tcctgttgat
    16321 atggaaacgg gtgaaattct gacagaggaa gctgttcaaa atcttccacc tattccagaa
    16381 gaaaagtggg tggaaccaga aatcatcctg tctcaagctg aacttaaatt ccctgaacag
    16441 gaagatgact cagatgacga agatgttcag gtcgattttt cagccaaaga agcccttaaa
    16501 tacaaacttc caagcttaca actctttgca ccagataaac caaaagatca gtctaaagag
    16561 aagaaaattg tcagagaaaa tatcaaaatc ttagaagcaa cctttgctag ctttggtatt
    16621 aaggtaacag ttgaacgggc cgaaattggg ccatcagtga ccaagtatga agtcaagccg
    16681 gctgttggtg taagggtcaa ccgcatttcc aatctatcag atgacctcgc tctagccttg
    16741 gctgccaaag atgtccggat tgaagcacca atccctggga aatccctaat cggaattgaa
    16801 gtgcccaact ccgatattgc cactgtatct ttccgagaac tatgggaaca atcgcaaacg
    16861 aaagcagaaa atttcttgga aattccttta gggaaggctg ttaatggaac cgcaagagct
    16921 tttgaccttt ctaaaatgcc ccacttgcta gttgcaggtt caacgggttc agggaagtca
    16981 gtagcagtta acggcattat tgctagcatt ctcatgaagg cgagaccaga tcaagttaaa
    17041 tttatgatgg tcgatcccaa gatggttgag ttatctgttt acaatgatat tccccacctc
    17101 ttgattccag tcgtgaccaa tccacgcaaa gccagcaagg ctctgcaaaa ggttgtggat
    17161 gaaatggaaa accgttatga actctttgcc aaggtgggag ttcggaatat tgcaggtttt
    17221 aatgccaagg tagaagagtt caattcccag tctgagtaca agcaaattcc gctaccattc
    17281 attgtcgtga ttgtggatga gttggctgac ctcatgatgg tggccagcaa ggaagtggaa
    17341 gatgctatca tccgtcttgg gcagaaggcg cgtgctgcag gtatccacat gattcttgca
    17401 actcagcgtc catctgttga tgtcatctct ggtttgatta aggccaatgt tccatctcgt
    17461 gtagcatttg cggtttcatc aggaacagac tcccgtacga ttttggatga aaatggagca
    17521 gaaaaacttc ttggtcgagg agacatgctc tttaaaccga ttgatgaaaa tcatccagtt
    17581 cgtctccaag gctcctttat ctcggatgac gatgttgagc gcattgtgaa cttcatcaag
    17641 actcaggcag atgcagacta cgatgagagt tttgatccag gtgaggtttc tgaaaatgaa
    17701 ggagaatttt cggatggaga tgctggtggt gatccgcttt ttgaagaagc taagtctttg
    17761 gttatcgaaa cacagaaagc cagtgcatcc atgattcagc gtcgtttgtc agttggattt
    17821 aaccgtgcga cccgtctcat ggaagagctt gagatggcag gtgtcattgg tccagctgaa
    17881 ggtaccaagc caagaaaagt attgcagcaa taaaaaatag cttctttcca aggttggaag
    17941 gagctatttt actggctatt gattactttt attttctgaa gttggagtat tgggctgttt
    18001 ttcattttca gtggcaggtt tacttgtagc aggtgtagta gagtcctgag ttgctgtttt
    18061 ctgatcttct tttttctctt ccttgacgct agattttggc gtttcttctt gttgtgtttt
    18121 ttcttgagaa gtgttatttt ccttatttgg agtagtattt tcctgagggg attctttttg
    18181 aatttctttg acaaaggttg tcgtctggct tgtcgtaggt tcttttttag tatttttatt
    18241 attattatcc aaggcgttca tgatcgtgat acccgctgta atcaaaccaa ggatactacc
    18301 gatagtagta atggtttttt gaaaaacagt aaagcctttt ttgatatgtt ctgttttcgg
    18361 ttttgaagtt ctacgatagt tagacataca ttctctcctt tgattatgat ttattatact
    18421 ctgtttcttt aaaaaaatct taaaaaaaga gaaattgccc tttcttgtcg caagctccgt
    18481 ttcatgatac aatagaggga gtgattttag aaagcgtgag aaacatgatt tactttgata
    18541 attcagcgac gaccaagcct tatcctgaag cccttgaaac ctatatgcag gtcgcttcaa
    18601 aaattttagg aaacccatct agtctccatc gtttgggaga ccaagcaaca cgaatcttag
    18661 atgcttctcg ccaacagatt gcagatttaa tcggtaagaa aatcgatgaa atcttcttta
    18721 cctctggtgg aacagaaggg gataactggg ttatcaaggg tgtggccttt gaaaaagctc
    18781 agtttggcaa gcacatcatt gtttcagcca ttgaacatcc agcagtcaaa gagtcagccc
    18841 tctggttgaa aagtcaagga tttgaagtgg attttgctcc agttgataag aaaggcttgg
    18901 tcgatgttga ggcgttagca ggtttgatac ggcctgatac aatcctcgtt tccatcatgg
    18961 ctgtgaacaa tgaaatcggc tctatccaac ctattgaggc tatttcagaa ttcttggcag
    19021 acaagccgac tatttccttc cacgttgatg cggttcaggc gcttgccaaa attccgactg
    19081 aaaagtatct gacagaacgg gtggattgcg cgaccttctc gagtcataaa tttcatggtg
    19141 tccgtggtgt tggctttgtc tatatcaaat ctggcaagaa gattacacct cttcttacag
    19201 gtggtggcca ggagcgagat tatcgttcga caactgaaaa tgtggcaggg attgcagcga
    19261 cagccaaggc tctccgttta tctatggaaa agctagatat ctttaggagc aagactgggc
    19321 agatgaaggc agtgattcac caagctcttc tgaactatcc ggatattttt gtcttttcag
    19381 atgaggaaga ctttgcacct catattctga cttttggaat caaaggtgtt cgaggtgaag
    19441 tcatcgttca cgcctttgaa gactatgata ttttcatctc aacaacctca gcttgttcat
    19501 ctaaggcagg aaaaccagcc ggtaccttga ttgccatggg agtggacaaa gataaggcca
    19561 agtcagctgt gcgtcttagc ctagacttgg aaaatgatat gagtcaggtc gagcagtttt
    19621 tgaccaagtt aaaattgatt tacaatcaaa ctagaaaagt aagataggag cattcatgca
    19681 gtattcagaa attatgattc gctacggaga gttgtcaacc aagggtaaaa accgtatgcg
    19741 tttcatcaat aaacttcgta ataatatttc ggacgttttg tctatctata cccaagttaa
    19801 ggtaacagca gatcgcgacc gtgcccacgc ttacctcaat ggagctgatt acacagcagt
    19861 tgcagaatct ctcaaacaag tttttggaat tcaaaacttt tctcctgttt ataaggttga
    19921 aaaatctgta gaagttttga agtcttctgt ccaagagatt atgcgggaca tctacaagga
    19981 aggtatgacc tttaagattt ctagcaagcg tagcgaccac aactttgaac ttgatagtcg
    20041 tgaactcaac caaacacttg gaggggctgt attcgaagcc attccaaatg tgcaagttca
    20101 aatgaaaagt cctgacatca atcttcaggt ggagattcgt gaagaagcag cctatctttc
    20161 ttatgaaacc attcgtgggg ctggtggttt gccagttgga acttcaggta aagggatgct
    20221 catgttgtca ggagggattg actcacctgt agcaggttat cttgctctta agcgtggggt
    20281 ggatatcgag gcagttcact ttgctagtcc accatatact agtcctggtg ccctcaagaa
    20341 agcgcaggac ttgacccgta aattgaccaa gtttggcgga aatatccagt ttatagaggt
    20401 gcctttcaca gagattcaag aggaaatcaa agccaaagcg ccagaagctt atttgatgac
    20461 tctaactcgt cgctttatga tgcggattac tgaccgtatt cgtgaggtac gaaatggttt
    20521 ggttatcatc aatggggaaa gtctaggtca agtagccagc caaacccttg aaagtatgaa
    20581 ggctatcaat gctgttacca acactcccat cattcgtcct gtggttacca tggacaagtt
    20641 ggaaatcatt gacatcgccc aggaaatcga tacctttgac atttcaatcc aaccgtttga
    20701 agactgttgt accatttttg caccagatcg tccaaaaaca aatcctaaaa ttaagaatgc
    20761 ggagcagtac gaagcgcgta tggatgttga aggcttggtt gagcgagcag tggctggaat
    20821 catgattact gaaatcacac ctcaagccga aaaagatgaa gttgatgact tgattgataa
    20881 tctactctaa ttcagaaaat ccaaaagaat agcgaaaatc agtaaaaaaa gttagttttt
    20941 tctctaaaaa caggtaaaaa actaactttt tttattttta tgatataatg atataaaatt
    21001 ttggctcttt gtcaactgta gtgggttgaa
//
LOCUS       DBEJNA010000038        19993 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEJNA010000038 DBEJNA010000000
VERSION     DBEJNA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.38"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            306..1751
                     /gene="cps4A"
                     /locus_tag="ACL3JB_001675"
     CDS             306..1751
                     /gene="cps4A"
                     /locus_tag="ACL3JB_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR0686371.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVAAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGIDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1753..2484
                     /gene="cps4B"
                     /locus_tag="ACL3JB_001676"
     CDS             1753..2484
                     /gene="cps4B"
                     /locus_tag="ACL3JB_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0686372.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYNALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2493..3185
                     /gene="cpsC"
                     /locus_tag="ACL3JB_001677"
     CDS             2493..3185
                     /gene="cpsC"
                     /locus_tag="ACL3JB_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR0686373.1"
                     /translation="MKEQNTLEIDVLQLFRVLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTSQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPADTRIVSVSVNDRVPEEASRIANSLREVAAKKIISITRVSDVT
                     TLEEARPAISPSSPNLKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLNKLK"
     gene            3195..3878
                     /gene="cpsD"
                     /locus_tag="ACL3JB_001678"
     CDS             3195..3878
                     /gene="cpsD"
                     /locus_tag="ACL3JB_001678"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HGR0686374.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVS
                     PGEGKTTTSVNIAWSFARAGYKTLLIDGDIRNSVISGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEANKRDVQKAQQQLKQTGKLFLGVVFNKLDISVDKYGVY
                     GFYGNYGKK"
     gene            3894..5261
                     /locus_tag="ACL3JB_001679"
     CDS             3894..5261
                     /locus_tag="ACL3JB_001679"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0686375.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFEKMG
                     MDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIVSLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMQIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5292..6464
                     /gene="cps2T"
                     /locus_tag="ACL3JB_001680"
                     /gene_synonym="wchF"
     CDS             5292..6464
                     /gene="cps2T"
                     /locus_tag="ACL3JB_001680"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGR0686376.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKTIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIVYDIAAINRAIKIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQEIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEKYIQEDYIQYQPKTTYIAYGTDTTRSTLNSSDEKVRAWFKEKNVSEN
                     EYYLVVGRFVPENNYESMIRGFLASSSKKDFVLITNVEQNKFYNQLLASTGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKIIDELDRQSNQRIVDFFTWEKIVTDYEKLFKK"
     gene            6461..7732
                     /locus_tag="ACL3JB_001681"
     CDS             6461..7732
                     /locus_tag="ACL3JB_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0686377.1"
                     /translation="MKILHYTLGFQPQRTGGLVKYAEDLMLEQIAQGYQVAALYPGRI
                     KFFSKKIEIIKETSRQFECYELLNSLPMALFGGISDPTAFLTPCDKNVYRTFLEKVQP
                     DIIHIHSFMGLHKEFLEIAKSLNIRVVFTSHDYYGLAPVPHFYFNGVDYSDKSTNLTW
                     NIMSSNALSVKKLRLFQVSFYPTIRKLLKLLGKNPKSKKNLVIRDVIEEQDYSELRYY
                     YNEMFHLIDGYLFNSRLAKKVYEINEIKSANSIVLSITNSSINHHQRLTTTNNKIRVA
                     YIGPDEEYKGYFDFVDFVETLDRESYEVATYGHLPNEECPSFIEQKGYFTKEMIDSVY
                     ENIDILIVPSKWKETFGLITVEALSYGVNVFVSENVGSKDLLPESHVFKNQNDLIVKF
                     LKNDIENTKLKTLDEHSIEVIQYYERVINDS"
     gene            7722..8408
                     /locus_tag="ACL3JB_001682"
     CDS             7722..8408
                     /locus_tag="ACL3JB_001682"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGR0686378.1"
                     /translation="MIVKSFIKKITGKTVDIHPDVPLSYILQRGINYSFGLFRGVVRG
                     IGFGQNDKRLFIGQGVSILAKRKLFVGKNVRIGKKVSIDALSKEGIHFADNVKIGDYS
                     QIIGTGSIKNMGIGLKIGKNSSFSEYSLFGSAGGITIGDNVIAGQNVRFHAENHNYSD
                     LDKLIVEQGVSRKGISVGDNCWIGAGSVFLDGSSIGSGCVVAANSVITKNFPDNVIVA
                     GVPAKIIKMK"
     gene            8420..9325
                     /locus_tag="ACL3JB_001683"
     CDS             8420..9325
                     /locus_tag="ACL3JB_001683"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0686379.1"
                     /translation="MRKEIKAVYAILNYNTWEDTARLAQKVATFQHIQSVIIVDNLST
                     DDSYHYLKRLEGEKISVYQTQRNGGYSVGNNFAARKAYNMGVDILFISNPDVDIDEKD
                     SLMIAQNLYKNSSYALLSGIEYNAMKEIDLPIVWHENSYYDDLLDCLFLTRKWRRKKE
                     DINLSMIKSSIIDVDLVKGSFFAVRLSDFHDVGYFDESVFLFCEERILAKKLQKVNKK
                     IGILPEAKYYHNHSTSINERYKKKKEQINLLYKSRYYYNVKYNNISFVKKLCLKSVMM
                     LSILEYIILDMMNLLYTKTNYKKIQ"
     gene            complement(9426..9788)
                     /locus_tag="ACL3JB_001684"
                     /pseudo
     CDS             complement(9426..9788)
                     /locus_tag="ACL3JB_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857010.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10015..11277
                     /locus_tag="ACL3JB_001685"
     CDS             10015..11277
                     /locus_tag="ACL3JB_001685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686380.1"
                     /translation="MSKLILNLKLNSFLFVIILLLVVVTPTHTLIFDALIPTKIDNLW
                     REFLLVISFLCILKINAGKIKIGKLGGPIIVMGGIGLVYTICSDRPFTALNLFRIYMF
                     PAVIYFIIINCNFRKERLLILKQAHVYTACILALWGIFQAWVLKDQFLIKIGYPSQGN
                     FLKSTAFYIGGFFGQQRVTSTFSAPNLAGVYFGISLIILLSIFDTIKSNRLVLFSIVA
                     AFVLTFSRSAIISTLVGIVFFQRKKLFSTTKINVMTLVIFPLIFLIVLVIFYLYPENV
                     IINMLYSSYSSTLNLTDSSAVKHLEDLWLPLLKVIDYPLGLGFGNNGPIVLSLYHSAN
                     LVESSIYLLAYDFGILGMFIYLFPYFYTIFVYKKYLLSGAICCLVLITYLFLPNVENF
                     EIIFFIYLFIGMDELALYTKGMNVHEID"
     gene            11264..12424
                     /locus_tag="ACL3JB_001686"
     CDS             11264..12424
                     /locus_tag="ACL3JB_001686"
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HGR0686381.1"
                     /translation="MKLIKLLKKYINLYISSSVPKTNKLLIFGSWLGEKYADNPRYLF
                     EYVIKNRPDLKAIWITSNQDVFKELQKKQYLVMMAEAPETRKIVKKAKYIFTATGIFD
                     IGEQNANFVGGAYLINLWHGIPLKKIMYDDKHSALHKRSKLVTWVEKIPLRNYFVIST
                     STAITQIYQSAFRVKKSNILELGQPRNDYFYDKSNPVSSLIQELKSKNIILYMPTHRN
                     EGKKQIDLDKLMDLEHLNNWCEETKSIFVIKKHFYHSKEKTIDKKYSSIIDVTNEKVD
                     VQELLKCSNVLITDYSSCYIDYLLLNRPIIFFNYDYDDYLRVDRSLYFPYENVTPGEK
                     CQNFDELLVTLQNLYVGKDDYREERENIKTFFYSSETQKSVSEKIINHVLNL"
     gene            12442..13881
                     /locus_tag="ACL3JB_001687"
     CDS             12442..13881
                     /locus_tag="ACL3JB_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0686382.1"
                     /translation="MKKILNKYYSLSNPVKASIWFTICNVLQKGISMITVPVFTRVLT
                     TEQYGVYSVYQSWYSIIGVFATLNLYYGVFNNGMIKYEKDKNVFTSSMQGLTTTVTAI
                     FLLIYLIGIDFWNSLLGLPTLLILVMFFDLFFTPAYSFWVARQRFEYKYRNLVFITFI
                     IAIGSPIIGISAVVLSTYKAEARVISFVLVQSCIGLYFYILNLYRGKHFFCKKYWLYA
                     LNFNLPLIPHYLSQSVLNQSDRIMINSMVGMGEAAIYSVAYSISILMLLVTSAINSSF
                     IPYTYKCIRDKKYTELGKSANLLITLVGIGSILTISLGPEIIQLFAPKQYYEAIWIIP
                     PVALSVYFMFLYPIFGNIEFYFEANHFVMWASIGGAIMNIFLNFIFLKHFGYIAAGYT
                     TLFCYILFALGHYIFMRRVLYQNLSGIQIYNSRYLLFFSILLIILMLLIVIIYPFILI
                     RYLTISLILGGCFLKRKKIMSSIAIIKQQ"
     gene            13891..14706
                     /locus_tag="ACL3JB_001688"
     CDS             13891..14706
                     /locus_tag="ACL3JB_001688"
                     /inference="COORDINATES: protein motif:HMM:NF016852.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0686383.1"
                     /translation="MTETNKQLHETLIEILDFVKEICEKHELTYFLVFGTALGAKRHC
                     GFIPWDDDVDIALPREHYNIFIDALSETDQSIFSLQNEDNEPNYFLPFAKLRKNNTIF
                     IEKILDVEYENNGIYIDIFPLDFVENPDSFNFKIRRTTFNYIKHILKFSSCRSFYKNK
                     YSNVRYLIENIMSIPTLFFSNRRLLFLANSLISSTTKADFIGQYDQKSNKRAIMPSNY
                     YFPPRSAVFEGKTYSVPAKLEDYLKCFYGSDYMELPPIEKRVTHQPITLRFEK"
     gene            14734..15126
                     /gene="tagD"
                     /locus_tag="ACL3JB_001689"
     CDS             14734..15126
                     /gene="tagD"
                     /locus_tag="ACL3JB_001689"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HGR0686384.1"
                     /translation="MKRVITYGTFDLLHHGHINLLRRAKELGDYLVVVVSSDEFNLIE
                     KNKVCYFNYEHRKSLVEAIRYVDLVIPETSWEQKRSDVKEYHIDTFVMGDDWIGEFDY
                     LKEEGVEVVYLPRTKEISTTKIKKDLSM"
     gene            15283..16152
                     /gene="rfbA"
                     /locus_tag="ACL3JB_001690"
     CDS             15283..16152
                     /gene="rfbA"
                     /locus_tag="ACL3JB_001690"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGR0686385.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            16153..16749
                     /locus_tag="ACL3JB_001691"
     CDS             16153..16749
                     /locus_tag="ACL3JB_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGR0686386.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            16759..17808
                     /gene="rfbB"
                     /locus_tag="ACL3JB_001692"
     CDS             16759..17808
                     /gene="rfbB"
                     /locus_tag="ACL3JB_001692"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGR0686387.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            17874..18725
                     /gene="rfbD"
                     /locus_tag="ACL3JB_001693"
     CDS             17874..18725
                     /gene="rfbD"
                     /locus_tag="ACL3JB_001693"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGR0686388.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            18822..19986
                     /locus_tag="ACL3JB_001694"
                     /pseudo
     CDS             18822..19986
                     /locus_tag="ACL3JB_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6564 a         2984 c         3976 g         6469 t
ORIGIN      
        1 gttcgctcac aataagagag aactttttta cgaaaatcta ttgaatatgc cataaaaaga
       61 ttatagcaca ttgtgtacta tagtagattg aaactagaat agtacacctc tgcttctaaa
      121 atattgttag aaatcgattt gactgtcctg atcgatttgt catgttctta tttcatttta
      181 ctatattttt ggttcgcggg aagtctacta agatacttaa agatgcagat agtgaaaata
      241 aaggtgtaga cattaccgta aaaaagtgat ataatcgtat gatgttcaat gtataggtgt
      301 taatcatgag tagacgtttt aaaaaatcag gttcacagaa agtgaagcga agtgttaata
      361 tagttttgtt gactatttat ttattgttag tttgtttttt attgttctta atctttaagt
      421 acaatatcct tgcttttaga tatcttaatc tagtggtaac tgcgttagtc ctactagttg
      481 ccttggtagg gctactcttg attatctata aaaaagctga aaaatttact atttttctgt
      541 tggtgttctc tatccttgtc agctctgtgt cgctctttgc agtacagcag tttgttggac
      601 tgaccaatcg tttaaatgcg acttctaatt actcagaata ttcaatcagt gtcgctgttt
      661 tagcagatag tgagatcgaa aatgttacgc aactgacgag tgtggcagca ccgactggga
      721 ctgataatga aaatattcaa aaactactag ctgatatcaa gtcaagtcag aataccgatt
      781 tgacggtcaa ccagagttcg tcttacttgg cagcttacaa gagtttgatt gcaggggaga
      841 ctaaggccat tgtcctaaat agtgtctttg aaaatatcat cgagtcagag tatccagact
      901 acgcatcgaa gataaagaag atttatacca agggattcac taaaaaagta gaagctccta
      961 agacgtctaa gaatcagtct ttcaatatct atgttagtgg aattgacacc tatggtccta
     1021 ttagttcggt gtcgcgatca gatgtcaata tcctgatgac tgtcaatcga gataccaaga
     1081 aaatcctctt gaccacaaca ccacgtgatg cctatgtacc aatcgcagat ggtggaaata
     1141 atcaaaaaga taaattaacc catgcgggca tttatggagt tgattcgtcc attcacacct
     1201 tagaaaatct ctatggagtg gatatcaatt actatgtgcg attgaacttc acttctttct
     1261 tgaaaatgat tgacttattg ggagggatag atgttcataa tgatcaagag ttttcagctc
     1321 tacatgggaa gttccatttc ccagtaggga atgtccatct agactctgag caagctttag
     1381 gttttgttcg tgagcgctac tccctagcag atggcgatcg tgaccgtggt cgcaaccaac
     1441 aaaaggtgat tgtggctatc cttcaaaaat taacgtcaac cgaagcactg aaaaattata
     1501 gtacgatcat tgatagcttg caagattcta tccaaacaaa tatgccactt gagaccatga
     1561 taaatttggt caatgctcag ttagaaagtg gtggaactta caaagtgaat tcgcaagact
     1621 tgaaaggtac aggtcggatg gatcttcctt cttatgcaat gccagacagt aacctctatg
     1681 tgatggaaat agatgatagt agtttagctg tagttaaagc agctatacag gatgtgatgg
     1741 agggtagatg aaatgataga catccattcg catatcgttt ttgatgtaga tgacggtccc
     1801 aaatcaagag aggaaagcaa ggctctcttg gcagaagcct acagacaggg ggtgcgaacc
     1861 attgtctcta cctctcaccg tcgcaagggc atgtttgaaa ctccggaaga gaagatagca
     1921 gaaaactttc ttcaggttcg ggaaattgca aaagaagtag cagatgattt agtcattgct
     1981 tatggcgcag agatatacta tactctggat gctctagaaa agctagaaaa aaaagaaatt
     2041 cctaccctta atgatagtcg ttatgccttg attgagttta gcatgcatac ttcctatcgt
     2101 cagattcata cgggattgag caatattttg atgttgggaa tcacgccagt aattgctcat
     2161 attgaacgtt ataatgcttt agagaataac gaaaaacgtg ttcgtgaact gattgatatg
     2221 gggtgctata ctcagataaa tagttatcat gtttcaaaac ctaagttctt tggtgaaaaa
     2281 tataaattca tgaaaaagag agctcggtat tttttggaac gtgatttagt tcatgtagtt
     2341 gcaagtgaca tgcacaattt agacagtaga cctccatata tgcaacaggc atatgatatc
     2401 attgctaaga aatatggagc gaaaaaagcg aaagaacttt ttgtagataa tcccagaaaa
     2461 attataatgg atcaattaat ttaggagaaa atatgaagga acaaaacact ttggaaatcg
     2521 atgtattgca actattcaga gttttatgga aaaggaagtt ggtcatttta ttagtggcaa
     2581 ttataacttc ttcagttgct tttgcctaca gtacttttgt tatcaaacct gagtttacta
     2641 gtacgactcg gatttatgta gttaaccgta atcagggaga gaagtctggt ttaaccagtc
     2701 aagacttgca ggcaggatcg tacttggtta aagactatcg tgaaattatc ctatcgcagg
     2761 atgttttgga ggaagttgtt tctgatttga aactagattt gacgccaaaa ggtttggcta
     2821 ataaaatcaa agtaacagta ccagctgata cccgtattgt ctctgtttca gttaatgatc
     2881 gagttcctga agaggcaagc cgtatcgcta actctttgag agaagtagct gctaaaaaaa
     2941 ttatcagtat tactcgtgtt tctgatgtga caacactgga ggaggcaaga ccggcgatat
     3001 caccgtcttc gccaaatctt aaacgcaata cactaattgg ttttttggca ggggtgattg
     3061 gaactagtgt tatagttctt cttcttgaac ttttggacac tcgtgtgaaa cgtccggaag
     3121 atatcgaaga tacactacag atgacacttt tgggagttgt accaaacttg aataagttga
     3181 aataggagag agagatgccg acattagaaa tagcacaaaa aaaactggag ttcattaaga
     3241 aggcagaaga atattacaat gccttgtgta caaatataca gttgagcgga gataaactaa
     3301 aagtaatttc cgttacttct gttagcccgg gggaaggaaa aacaactact tccgtaaata
     3361 tagcatggtc gtttgcgcgt gcaggctata aaactctttt gatcgatggc gatattcgaa
     3421 attcagtcat atcaggattt tttaaatctc gtgaaaaaat tacagggcta acagaatttt
     3481 tatctgggac agctgattta tctcacggtt tatgtgatac aaatattgaa aatttatttg
     3541 tagttcaatc gggctctgta tcaccaaacc ctacagcctt gttacaaagt aaaaatttta
     3601 atgatatgat tgaaacattg cgtaaatatt ttgattatat cattgttgat acagcaccta
     3661 ttggaattgt tattgatgcg gcaattatca ctcaaaagtg tgatgcgtcc atcttggtaa
     3721 cagcaacagg tgaggcgaat aaacgtgatg tccaaaaagc gcaacaacaa ttaaaacaaa
     3781 cagggaaact gttcctagga gttgttttta ataaattaga tatctcggtt gataagtatg
     3841 gagtttacgg tttctatgga aattatggta aaaaataact taggaaagat tttatggatg
     3901 aaaaaggatt gaaaattttt ctggcagtat tacagagtat tattgtcatt ttattggttt
     3961 attttcttag ctttgttaga gagacagaac ttgaacgttc ttcgatggtt atactatacc
     4021 ttctccactt ttttgtattc tattttagtt cctatggtaa caattttttt aaaagagggt
     4081 acctagttga gtttaatagt actataagat atattttttt ctttgcaata gctataagtg
     4141 tattaaactt ttttatagcg gaacggttta gcatctctag aagaggaatg gtatacttct
     4201 taactttaga aggaatatcc ttatacttgt taaatttctt agtaaagaaa tattggaagc
     4261 atgtgttttt taatctaaaa aatagcaaga aaattttact gttaacagta acgaaaaata
     4321 tggaaaaagt tcttgataaa ttgctagaat ctgatgaact ttcatggaaa ttggtagcag
     4381 taagtgtttt ggataaatct gattttcaac atgataaaat acctgtaatt gaaaaggaaa
     4441 aaattattga atttgcaacg catgaagttg tggatgaggt gtttgtcaat cttccaggag
     4501 agagctacga tattggagaa attatctcta ggtttgagaa aatggggatg gatgtaactg
     4561 taaatcttaa agcatttgat aagaatttgg gtcgcaataa acaaattcat gagatggtag
     4621 gattgaatgt agtcactttc tctacaaatt tttataaaac tagtcatgtg atttcaaaga
     4681 gaattctcga tatttgtggt gccactattg gccttattct ttttgctata gttagtctag
     4741 ttttagttcc attgattcgt aaagatggcg gaccagctat ttttgctcaa actcgtatag
     4801 ggaaaaatgg tcgacatttt accttttata aattccgttc gatgcagatc gatgctgaag
     4861 ctatcaaaga acagttgatg gatcaaaata cgatgcaagg tggtatgttt aagatagaca
     4921 atgatcctcg tgttacaaaa attggtcgct ttattcgtaa aaccagttta gatgagttac
     4981 cccagttttg gaatgtcttt ataggagata tgagtttggt gggaacacgt ccacctacag
     5041 tagacgagta tgatcagtat actccagaac agaaacgtcg actcagcttt aaacccggta
     5101 ttacaggttt atggcaggtt agcggccgta gtaaaataac cgattttgac gatgttgtaa
     5161 aattagatgt ggcttatatt gataattgga caatctggaa agatattgaa attttgctta
     5221 aaactgttaa agttgtattt atgagagatg gagcgaagta atttctgtat atccatcata
     5281 ttaggagaga aatgaaaaag tcagtttata tcattggttc aaaaggaatt cctgctaagt
     5341 atggaggatt tgaaactttt gttgaaaaat taacagcctt ccaacaagat aagactatcc
     5401 aatattatgt ggcttgtatg cgtgaaaact ctgcaaaatc agggactact gaggatgttt
     5461 ttgaacataa tggtgctatc tgttataacg tcgatgttcc taatattggt ccagcgcgag
     5521 ccatagtata tgatatcgcg gcaattaaca gagctattaa aattgccaaa gaaaataagg
     5581 atgaagatcc aatcttctat attctagctt gtcgaatcgg tccgttcatc catggaatta
     5641 agaaaaaaat ccaggagata ggtgggactc ttctagttaa tccagatggt cacgagtggt
     5701 tacgagctaa gtggagcgct ccagttcgtc gttattggaa aatttccgaa ggtcttatgg
     5761 tcaaacatgc agatctttta gtgtgtgata gtaagaatat tgaaaaatat atccaagaag
     5821 attatataca gtatcaacct aagacaacct atatcgctta tgggacagat acaacacgct
     5881 ccacattaaa tagcagtgat gaaaaagtgc gtgcttggtt caaggagaaa aatgtttctg
     5941 aaaacgagta ttacctagtt gtaggacgtt ttgttccaga aaataattat gagtctatga
     6001 tacgtggttt cttggcgtct agctctaaga aggattttgt cctaatcaca aatgtagaac
     6061 agaataaatt ttataatcag ctattagcaa gtactggatt tgataaagat ccacgagtga
     6121 aatttgttgg aacagtctac gaccaagaac ttctgaagta tattcgagaa aatgcttttg
     6181 cttacttcca cggacatgaa gttggtggaa caaatccttc gttacttgaa gcattagcat
     6241 ccacaaagtt aaacttacta ctcgatgttg gttttaaccg cgaagttggg gagcaaagtg
     6301 cgatctattg gaaaaaagat gagctttccc aagtaatcga gaaagttgaa caatttgatg
     6361 caaaaattat tgatgagtta gatagacaat caaatcagag aattgtggat tttttcactt
     6421 gggaaaagat tgtcacagac tacgagaaat tatttaaaaa atgaaaatat tacattatac
     6481 tttaggattt caaccccagc gaacaggtgg tttggttaaa tatgctgagg atttaatgct
     6541 agagcaaatt gctcaaggtt atcaagtggc tgccctatat ccaggaagaa ttaagttctt
     6601 ttcaaaaaaa atagaaataa ttaaagagac gtcaagacag tttgagtgtt atgagctgct
     6661 taatagctta cctatggctt tatttggagg gatatccgat ccaactgctt tcctgacacc
     6721 ttgtgacaaa aatgtttatc gtactttttt agaaaaagta caacccgaca ttatacatat
     6781 tcactcgttt atgggattgc ataaagaatt cctcgaaatt gctaaaagct tgaatattag
     6841 agtggttttt acgagccatg attattatgg attagcaccc gtacctcatt tctattttaa
     6901 tggggtggat tatagtgata aaagtacaaa cttaacatgg aatattatgt cttccaatgc
     6961 tttaagtgtg aaaaaactaa gactttttca ggtttcattt tatcctacta ttcgtaaact
     7021 tttgaaacta ttagggaaaa atccaaaatc taaaaagaat ttagttattc gagatgttat
     7081 tgaggagcaa gattatagtg agcttcgata ctattataat gagatgtttc acttaataga
     7141 tggttatttg tttaatagta gacttgcaaa gaaggtatat gagataaatg agattaagtc
     7201 agctaatagt atagtattat ctataacaaa tagttcaatt aatcatcatc agagattgac
     7261 aactacaaat aataaaatta gagttgctta tattggtcca gatgaagaat ataaaggata
     7321 ttttgatttt gttgactttg ttgaaacttt agatcgagag tcctatgaag tggcaactta
     7381 tggccattta ccaaatgaag agtgtccttc attcattgaa caaaaaggat attttactaa
     7441 ggaaatgatt gacagtgtct atgaaaatat tgatattctt attgttccaa gtaagtggaa
     7501 ggaaacattt ggattgataa cagtagaagc attatcctat ggggtaaatg ttttcgtgag
     7561 tgaaaatgtt gggtcaaaag acttacttcc agaatcgcat gtttttaaaa atcagaatga
     7621 tttaatagtt aaatttttaa aaaatgatat agaaaataca aaattgaaaa ctttagatga
     7681 acactcgata gaagtgattc agtattatga aagagtgata aatgatagtt aagagtttca
     7741 taaaaaagat tactggaaaa acagtagaca ttcatccaga tgtacctttg tcgtatatac
     7801 tacaaagagg tataaactat agtttcggac tctttcgtgg ggttgtacgt ggaatcggat
     7861 ttggtcaaaa cgacaaacgt ttattcattg gacaaggagt ttctatctta gcaaagcgta
     7921 aattatttgt tggaaaaaat gttcgaattg gtaaaaaggt gtctatagat gcactgtcaa
     7981 aagaaggaat ccattttgca gataatgtaa agattggaga ttattctcaa attattggca
     8041 caggttctat aaaaaatatg gggattggct tgaaaatcgg taagaactca tctttttcag
     8101 aatatagttt atttggttct gctggaggta tcacaattgg tgataatgtt atcgcaggtc
     8161 agaatgttcg ttttcatgct gaaaatcata attatagtga tttagataaa ctcattgttg
     8221 aacaaggggt atctcgaaag ggaatttcag taggtgataa ttgttggatt ggtgctggat
     8281 ctgttttttt ggatgggtcc agcattggtt caggttgtgt tgtagctgca aattctgtaa
     8341 ttacgaaaaa ctttccagat aacgttattg ttgctggagt accagctaaa attataaaaa
     8401 tgaaatgata ggatgttaaa tgaggaaaga aattaaagct gtttatgcga tattaaatta
     8461 caatacttgg gaagatactg cgcgtttagc acagaaagtt gcaacatttc agcatattca
     8521 atctgtgata atagtggata atctatcaac agatgattca taccattatt taaaaagact
     8581 tgagggagag aaaatttcag tttatcaaac acaaagaaat ggtggatatt ctgttggaaa
     8641 taattttgca gcacgaaaag cttataatat gggagttgat attcttttca tttcaaatcc
     8701 agacgttgat attgatgaaa aagattcctt gatgattgca caaaatttgt ataaaaatag
     8761 ttcatatgca ctgttatcag gtatagaata taatgctatg aaggagatag atttgccaat
     8821 tgtctggcat gaaaattcct attacgatga cttacttgat tgtttgtttt taaccagaaa
     8881 atggcgaaga aaaaaagaag atatcaattt gtcaatgatt aaatcatcta taatagatgt
     8941 agatcttgtt aaaggatcgt tttttgctgt aagactgtct gattttcatg atgttggtta
     9001 ttttgatgaa tctgtatttc ttttttgtga agagagaata ttagctaaaa agttacaaaa
     9061 agtaaataaa aaaataggta ttctgcctga agcgaaatat taccacaatc attcaacttc
     9121 tataaatgag agatataaaa agaaaaaaga acagattaat ttattatata agtctcgata
     9181 ctactataat gtaaagtata ataatattag ttttgtcaaa aaactatgtt taaaatctgt
     9241 catgatgcta tccattttag aatatataat cttagatatg atgaatttat tatatacaaa
     9301 gactaactat aagaaaattc aatagtttaa tctgaaatac ttcttgtttc aaagtggatg
     9361 attttagagc acggcaaaat gtccttgaaa aagtttattt tttcaaaggt tatcttgtgg
     9421 caaattcagg agttagaaca ctttttttcg tcaaatgcta gcttgttttt taggagataa
     9481 aacagatttc taataagttt tttggcaagg tgaatgatgg ctacattgta atgctttctt
     9541 tgttacaact tagtcctaag ataggcttta aaaacaggcg aaaagcgagc atatgctttg
     9601 gtagcttgta tgagtgccca acgtagatga ggggaaccca gtttgaccat tttccctgct
     9661 aaatcgattt gacctgactg gtaaatagaa ggattcggtc cagcaaaagc ttgtaattga
     9721 tgaggcttat cgaagatatg aatacttcga atctcaacta agataacgtc acctaaacga
     9781 ttcccaagct cacttggtta tccacgaact ttgtgccttg ttaccttaca caatataaaa
     9841 cgtttatgcg ctatcaaact cattaccaat tgaaacaaaa agctgtggtt agagcctttc
     9901 agaaatcgtc aagcgattgg aggaaatgaa ctaatccaca gtggcttatt ccaagtgtac
     9961 cacttggact ttagcagtag cgaactacac taaatataat ataaggagaa ataggtgagt
    10021 aaattaatat tgaacttgaa attaaattct tttttatttg ttataatttt acttttagtt
    10081 gttgttactc cgactcatac cttaattttt gatgcactaa ttccaacgaa aattgataat
    10141 ttatggagag agtttcttct agtaatttct tttctatgta ttctaaagat aaatgcagga
    10201 aaaattaaaa ttggaaagct agggggccca ataattgtta tgggaggaat tggtttagtt
    10261 tatactatct gttcagatag gccatttaca gctttaaatc tttttagaat ttatatgttt
    10321 cctgctgtaa tatattttat aataataaat tgtaattttc gcaaggagag attactgata
    10381 ttgaagcaag cgcatgtata tactgcttgc atattagctt tatggggaat ttttcaggcg
    10441 tgggtgttaa aagatcagtt tttgattaaa ataggatatc cttcccaagg aaattttcta
    10501 aagagtacag ctttttatat tggtggtttt ttcggtcaac aacgagttac tagcactttt
    10561 tctgctccta atttagctgg agtttatttt ggaatatctt tgatcatttt actctctata
    10621 tttgatacta taaagagtaa tagattggta ttgttttcaa ttgtagcagc ttttgttctt
    10681 acatttagcc gtagtgctat tataagtact cttgtaggaa tcgtattctt tcaacgtaag
    10741 aaattgtttt caacgacgaa gattaatgtt atgaccttgg taatcttccc cttaattttt
    10801 ttgattgttt tagttatatt ttatctttat cctgagaatg ttattataaa tatgctctat
    10861 agcagttatt cttcaacact taatttgaca gattcttcag cggttaagca tttggaagac
    10921 ttatggcttc ctcttctaaa agttattgat tatcctttgg gacttggatt tggtaataat
    10981 ggcccaattg ttctgtcact ctatcactca gcaaatttag tagaatcttc tatttatctt
    11041 cttgcatatg attttggtat tttaggaatg ttcatatatt tgttccctta tttttatacg
    11101 atttttgtat ataaaaaata tttgcttagc ggtgctatat gctgcttagt tcttataact
    11161 tatctatttc ttccaaatgt agaaaatttt gaaatcatat tttttattta ccttttcatt
    11221 gggatggatg aactagcact atatacaaaa ggaatgaatg tacatgaaat tgattaaatt
    11281 attgaaaaaa tatataaatt tatacattag tagttcggtg cctaagacaa ataaattgtt
    11341 aatttttgga tcatggttag gtgaaaaata tgcagacaat ccaagatatt tgtttgagta
    11401 tgtgattaag aatcgtcccg atttaaaagc tatatggatt acaagtaatc aagatgtttt
    11461 taaagaatta cagaagaaac aatatctcgt gatgatggca gaggcacctg aaactcggaa
    11521 aattgttaaa aaagcaaagt atatttttac agcaactggt atttttgata ttggagaaca
    11581 aaatgctaac ttcgttggag gtgcctatct aattaatcta tggcatggca ttcctttgaa
    11641 aaaaatcatg tatgatgata aacattcagc acttcacaaa cgtagtaaac tagtgacttg
    11701 ggtagaaaaa attcctcttc gaaactattt tgttatttct actagtacgg caataactca
    11761 aatttatcag tctgcttttc gcgtaaagaa atctaatata ttagaacttg gtcaacctag
    11821 gaatgactat ttttatgata agtctaatcc agtgagttca ttaatacagg aattaaaaag
    11881 taaaaatatt atcttatata tgccgacaca tcgcaatgaa ggaaagaaac aaatagatct
    11941 agataagtta atggatttag aacacttaaa taattggtgt gaagaaacaa agtcaatttt
    12001 tgtaattaaa aagcatttct atcattcaaa agaaaaaact atcgataaga aatattcttc
    12061 gataattgac gtgacaaatg agaaggtgga tgttcaagaa ttactcaaat gttcaaatgt
    12121 tttaataact gactactcaa gctgctatat tgactactta ttgttgaatc gtccaattat
    12181 attttttaat tatgattatg atgattactt gcgggtggat cgttcgctat attttccata
    12241 tgagaatgtt actccagggg agaaatgtca aaactttgat gaattattag tgactttgca
    12301 aaatctatat gtaggaaaag atgattatag agaagaacgt gaaaatatca aaactttctt
    12361 ttattctagt gaaactcaga agtcagtttc tgaaaaaata attaatcacg tactaaatct
    12421 ataactttat tggaatctgt catgaaaaaa atattaaata agtattattc tttatctaat
    12481 cctgtaaaag cttcaatttg gtttactatt tgcaatgttc ttcaaaaagg aatttcaatg
    12541 attactgttc cagtttttac tagagtattg acaacggaac aatatggtgt atactctgta
    12601 tatcaatcat ggtattcaat aattggagtt tttgcaacac taaacctata ttatggagtc
    12661 tttaataatg gaatgattaa atacgagaaa gataaaaatg tctttacttc ctctatgcag
    12721 ggactaacaa caacagttac agctatattt ttactgatat atttaatagg gattgatttt
    12781 tggaactcgt tgttaggctt acctacacta ctaatcttag tgatgttctt tgatttgttt
    12841 tttacccctg cttattcttt ttgggttgct cgtcagagat ttgaatataa atatagaaac
    12901 ttagtattta tcacatttat tatagcgatt ggaagtccta ttattggtat ttctgcagtt
    12961 gttttatcga cttataaagc ggaggctaga gttatctcat ttgtgttagt tcaatcttgt
    13021 atagggttat atttctatat tttgaacctt taccgaggta aacatttttt ttgtaaaaaa
    13081 tattggctct atgctttgaa ttttaattta cctcttattc ctcattattt atcgcaatca
    13141 gttttaaacc aatcggatag aataatgatt aattcaatgg taggaatggg agaagcagca
    13201 atatatagtg ttgcttacag catatcaatt ttgatgcttt tagtgacaag tgctataaac
    13261 agctctttta ttccttacac atataagtgt attcgagata agaaatatac tgaactaggg
    13321 aaaagtgcaa atcttttaat tactctggta ggcattggtt cgattttaac tatttctctt
    13381 ggaccagaaa tcattcaatt atttgcacca aaacaatatt acgaagcaat atggattatt
    13441 cctcctgttg ctctgtcagt atatttcatg ttcttatatc ccatttttgg taacattgag
    13501 ttttactttg aagcaaatca ttttgtaatg tgggcttcaa tcggtggagc aattatgaat
    13561 atttttttga attttatttt tttaaaacac tttggatata ttgcggcagg ctatacaact
    13621 ttattctgtt atattttatt tgcgttggga cattacattt ttatgaggag agtactgtat
    13681 cagaatcttt cgggtatcca aatttataat tccagatatc ttttattttt ttcgattctt
    13741 cttattattc taatgctact aatcgtgatt atttatccat ttatactgat tcgttatctt
    13801 actatctcac tcatcctagg aggatgtttt ttaaagagga aaaagataat gagttcgata
    13861 gctatcatta aacaacagtg aggtacaaga atgacagaaa caaataaaca gttacatgaa
    13921 acattaatcg aaattttaga ctttgtaaaa gaaatttgtg aaaaacatga attaacttat
    13981 tttttggtct ttgggacagc tcttggagca aaacgccatt gtggatttat tccatgggat
    14041 gatgatgttg atattgcttt gccacgagag cactacaata tatttatcga tgcattatct
    14101 gagacggatc aatctatatt tagtcttcaa aatgaagata acgagccgaa ttatttttta
    14161 ccatttgcta aattaagaaa aaacaatacg atttttattg agaagattct tgatgttgaa
    14221 tatgagaata acggcattta cattgatatt tttccactag atttcgtaga gaatccggac
    14281 tctttcaatt ttaagattag gagaactaca tttaattata taaagcatat tttaaaattt
    14341 tcaagttgca gaagttttta taaaaataaa tacagtaatg tgcgttattt gattgaaaat
    14401 attatgagta ttcctaccct gtttttttca aataggagat tattattctt agcgaatagt
    14461 ttaatttcat caacgactaa agctgatttt attggtcaat atgatcagaa aagtaacaaa
    14521 agagctatta tgccttcaaa ctattatttt ccacctaggt ccgctgtgtt tgaaggaaag
    14581 acctatagtg ttcctgcgaa attagaagat tatttaaaat gtttttatgg ctcggattat
    14641 atggaattac caccaataga aaaaagagtc actcatcaac caataacact tagattcgaa
    14701 aaataatttg ctattctgta gaaggagaat ataatgaaaa gagtaattac atatggaacg
    14761 tttgatttac ttcatcatgg acatatcaat ttattgcgac gtgcaaaaga attaggtgac
    14821 tatctagtgg tagttgtttc aagtgatgaa ttcaacctaa ttgaaaaaaa taaagtttgt
    14881 tatttcaatt atgagcatag aaaaagtcta gttgaagcta ttagatatgt tgaccttgtt
    14941 attcctgaaa cgagttggga acaaaaacgc agtgatgtca aagagtatca tattgatact
    15001 tttgtgatgg gggatgattg gattggagaa tttgattatc taaaagaaga aggagttgaa
    15061 gtcgtttact tacctcggac gaaagaaatt tcgacaacta aaataaaaaa agatttatca
    15121 atgtaatatt cgtaaataag cattgttctg ttattgttct cgaatagacc actgtatttt
    15181 taagtagaaa tgctaaaatc gatagaaaag agaaaaatga taggacacta ccaatatagg
    15241 taaaaaatat cgtaattaga taaataagaa aggtacccta ctatgaaagg tattattcta
    15301 gcaggtggtt cggggacacg tttatatcct ttgactcgcg ctgcatcaaa acaacttatg
    15361 ccggtttatg ataaaccgat gatttactac ccactttcaa cattgatgtt ggctgggatt
    15421 agggatattt tgattatttc cactccacag gatttacatc gattccaaga gcttcttcaa
    15481 gacggatctg agtttgggct caaactttct tatgcagagc aaccaagtcc agatggtttg
    15541 gcacaagcct ttatcattgg ggaagagttt atttctgatg atagcgttgc gctgatctta
    15601 ggtgacaata tctatcacgg ttctgggctt tccaagatgc tacaaaaggc agcgagtaag
    15661 gagtcgggag caactgtttt tggctaccat gtcaaggatc cagagcgctt tggtgtggtt
    15721 gagtttgatc aggatatgaa ggctatttct attgaagaaa agccagagca acctcgttca
    15781 aactatgcag ttacaggtct ctatttctat gataatgatg tagtagagat tgccaagagt
    15841 attaaaccaa gtcctcgtgg tgaactggaa attacagatg taaacaaggc ttacctagat
    15901 cgtggtgatt tgtctgttga gcttatggga cgtggctttg cttggctgga tactggaact
    15961 catgaaagtt tactagaggc ttcacagtac atcgaaacag tgcaacggat gcaaaatgtt
    16021 caggtagcaa acttagaaga aattgcttac cgtatgggct atatcagtcg agaagatgta
    16081 ttggccttag cccaaccact taagaaaaat gaatacggac agtatctgct ccgtttgatt
    16141 ggagaagcat agatgacaga taattttttc ggtaagacgc ttgcggcacg caaggttgaa
    16201 gctattccag gcatgttgga gtttgatatc cccgttcatg gagataatcg tggctggttt
    16261 aaagaaaatt tccaaaagga aaaaatgctt ccacttggat ttccagagtc tttctttgca
    16321 gaaggaaaat tgcaaaacaa tgtatccttc tcacgtaaaa atgtccttcg aggtctccac
    16381 gcagagcctt gggataagta catctctgta gcagatggag ggaaagttct gggttcttgg
    16441 gttgatctac gcgagggtga aacctttggg aatacctatc agacagtgat tgatgcgagt
    16501 aagggaatct ttgttcctcg aggcgtagct aatggcttcc aagttttatc agatacagtg
    16561 tcatatagct atctggtcaa tgattactgg gctcttgaac tcaaacccaa gtatgccttt
    16621 gtgaactacg ctgatccaag ccttggtatt gaatgggaaa atattgcaga agcagaggtt
    16681 tcagaagcag acaaacatca tccactactt aaggatgtaa aacctttgaa aaaagaagat
    16741 ttggaataag gaaagaatat gactgaatac aaaaatatta tcgtgacagg tggagctggc
    16801 tttatcggtt ctaactttgt ccattatgtt tacgagaact ttccagatgt tcatgtgaca
    16861 gtcctagata agttgactta tgctggaaac cgcgcgaata ttgaggaaat tttaggtaat
    16921 cgtgttgagt tagttgttgg tgacattgct gatgcggagt tggtagacaa gttggctgct
    16981 caagcagatg ctatcgttca ttatgcagcg gaaagccaca atgataattc gctcaatgat
    17041 ccatcgccat ttattcatac taacttcatc ggaacctata ctcttttaga agctgctcgt
    17101 aagtatgata ttcgcttcca ccatgtatcg acagatgaag tttatgggga tctcccttta
    17161 cgcgaagatt tgccaggtca tggtgaagga ccaggtgaga aatttactgc tgaaacaaaa
    17221 tacaacccaa gctctccgta ctcatcaacc aaggcagcct cagatttgat tgtcaaagcc
    17281 tgggtgcgtt cttttggagt caaggcaacg atttccaact gttcaaataa ctacggtcct
    17341 tatcaacata tcgaaaaatt catcccacgt cagattacta acatcctaag tggaattaag
    17401 ccaaaacttt acggtgaagg taagaatgtt cgtgactgga ttcataccaa tgaccattct
    17461 tcaggagttt ggacaatctt gacaaaaggg caaatcggtg aaacctactt gattggggct
    17521 gatggtgaga agaacaataa ggaagttttg gaacttatcc ttaaggaaat gggacaagct
    17581 acggatgcct atgatcatgt gactgaccgt gcaggacatg accttcgcta tgcgattgat
    17641 gccagcaagc tccgtgatga gttggggtgg aaacctgaat ttaccaactt tgaagctggg
    17701 ctcaaggcaa caatcaagtg gtatacagat aaccaagaat ggtggaaagc agaaaaagaa
    17761 gctgttgaag ccaattatgc taagactcag gagattatta cagtataaaa agcaggaaat
    17821 agctgctttt tattgctata ttgggaagag ttacatatta gaaaggtcta gagatgattt
    17881 taattacagg ggcaaatggc caattaggaa cggaacttcg ctatttattg gatgaacgta
    17941 atgaagaata cgtggcagta gatgtggctg agatggacat taccaatgaa gaaatggttg
    18001 agaaagtttt tgaagaggtg aaaccgactt tagtctacca ttgtgcagcc tacaccgctg
    18061 ttgatgcagc agaggatgaa ggaaaagagt tggacttcgc catcaatgtg acggggacaa
    18121 aaaatgtcgc aaaagcatct gaaaagcatg gtgcaactct agtttatatt tctacggact
    18181 atgtctttga cggtaagaaa ccagttggac aagagtggga agttgatgac cgaccagatc
    18241 cacagacaga atatggacgc actaagcgta tgggggaaga gttagttgag aagcatgtgt
    18301 ctaatttcta tattatccgt actgcctggg tatttggaaa ttatggcaaa aacttcgttt
    18361 ttaccatgca aaatcttgcg aaaactcata agactttaac agttgtaaat gaccagtacg
    18421 gtcgtccgac ttggactcgt accttggctg agttcatgac ctacctagct gaaaatcgta
    18481 aggaatttgg ttattatcat ttgtcaaatg atgcgacaga agacacaaca tggtatgatt
    18541 ttgcagttga aattttgaaa gatacagatg tcgaagtcaa gccagtagat tccagtcaat
    18601 ttccagccaa agctaaacgt ccgctaaact caacgatgag cctggccaaa gccaaagcta
    18661 ctggatttgt tattccaact tggcaagatg cattgcaaga attttacaaa caagaagtga
    18721 gataagtagt agaatgattt tctagtctaa taaaagaggc agataatgaa ctccaaagga
    18781 gcttaagatg tacgcttatc ttgttgttgg tgctggtctc tttggcgcat agctttggct
    18841 cagtttctat tatcgctcac accatccatc agaagtttaa tctgaaggta cccaattatc
    18901 gccaagaaga agattgggct aggatgggtt taccaatcac acgtaaggaa atctctaatt
    18961 ggcatatcaa ggcaagtcaa tactatttag agtcccttta taagctttta cgagaaaagt
    19021 tgttagaaca acctcttctt cctgcggatg aaacctctta tcgggttcta gagagtgata
    19081 gccatctgac ctactattgg acctttttgt ctgggaaagc tgagaatcaa gcaatcacgc
    19141 tgtaccatca tggtcagtgt cgaagtggtt tagtagtaca agaattccta ggagattatt
    19201 ctggctatgt gcattgtgat atgttgcggc agtaacttag gactttagtc ctctagttct
    19261 gcctatgcga tagcagtcca aggtttagga gcaaggcgac gctaagcttg gtaaactgcg
    19321 aaccgctaga agcttatcgt caactggaag aagctgcact tgttggatgt tgggcacatg
    19381 tgagaaggaa gttttttgaa gcgaccccca agcaagcgga taaatcatcc ttaggagcta
    19441 aaggtttagc ttattgtaat cagttatttt ccttggaaag agactgggag gctttgccag
    19501 ctgatgaacg actacagaaa cgtcaagaag agctccaacc cttaaaggaa gacttctttg
    19561 cttggtgccg ccgtcagtca gttttagcag gttcaaaact aggaagggca attgaataca
    19621 gcctcaagta tgaagaaacc tttaagacta ttttgaaaga cggacatctg gtcctttcca
    19681 ataatctagc tgaatgctcc attaaatcat tggttatggg acggagtaaa agagtccagt
    19741 ggactctttt agcctaagct cagtttaaaa aagcgagggt ggttattttc tcaaagtttt
    19801 gaaggagcta aagcaagagc tattattatg agtttgttgg aaacagctaa acgtcatcaa
    19861 ttaaatagag agaaatatct attctatctt ctagaatgtc ttccaaacga ggaaactctc
    19921 gtaaacaaag aggttttaga ggcttattta ccatggacta aagttgtaca agaaaagtgc
    19981 aaataagaaa tct
//
LOCUS       DBEJNA010000039        19254 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEJNA010000039 DBEJNA010000000
VERSION     DBEJNA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.39"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            87..3437
                     /locus_tag="ACL3JB_001695"
     CDS             87..3437
                     /locus_tag="ACL3JB_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0686389.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDQEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3942..4412)
                     /locus_tag="ACL3JB_001696"
     CDS             complement(3942..4412)
                     /locus_tag="ACL3JB_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0686390.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4429..6702)
                     /locus_tag="ACL3JB_001697"
     CDS             complement(4429..6702)
                     /locus_tag="ACL3JB_001697"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0686391.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEVELEVKLPHKIELEEPQLNLVQPQGQAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7048..10149
                     /locus_tag="ACL3JB_001698"
     CDS             7048..10149
                     /locus_tag="ACL3JB_001698"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0686392.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGVK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQLRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            10231..11238
                     /gene="pfkA"
                     /locus_tag="ACL3JB_001699"
     CDS             10231..11238
                     /gene="pfkA"
                     /locus_tag="ACL3JB_001699"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0686393.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11295..12800
                     /gene="pyk"
                     /locus_tag="ACL3JB_001700"
     CDS             11295..12800
                     /gene="pyk"
                     /locus_tag="ACL3JB_001700"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0686394.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAIEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13019..13372)
                     /locus_tag="ACL3JB_001701"
     CDS             complement(13019..13372)
                     /locus_tag="ACL3JB_001701"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HGR0686395.1"
                     /translation="MTLQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHK
                     NAKTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDKYITIAKTFVEIHLNFLIN
                     LCISYFILNENQRAN"
     gene            complement(13542..13757)
                     /locus_tag="ACL3JB_001702"
     CDS             complement(13542..13757)
                     /locus_tag="ACL3JB_001702"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR0686396.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRESCQAI"
     gene            14605..15477
                     /locus_tag="ACL3JB_001703"
     CDS             14605..15477
                     /locus_tag="ACL3JB_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0686397.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLDTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15626..15966)
                     /locus_tag="ACL3JB_001704"
                     /pseudo
     CDS             complement(15626..15966)
                     /locus_tag="ACL3JB_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16109..16420
                     /locus_tag="ACL3JB_001705"
     CDS             16109..16420
                     /locus_tag="ACL3JB_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686398.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            16424..17140
                     /locus_tag="ACL3JB_001706"
     CDS             16424..17140
                     /locus_tag="ACL3JB_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0686399.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(17270..18085)
                     /locus_tag="ACL3JB_001707"
     CDS             complement(17270..18085)
                     /locus_tag="ACL3JB_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0686400.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(18082..18987)
                     /locus_tag="ACL3JB_001708"
     CDS             complement(18082..18987)
                     /locus_tag="ACL3JB_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0686401.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(18988..19119)
                     /locus_tag="ACL3JB_001709"
     CDS             complement(18988..19119)
                     /locus_tag="ACL3JB_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0686402.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
BASE COUNT         5987 a         3303 c         4111 g         5853 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtggaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctt tggagaaaca tatcggctat cagccaattt
      961 gctttattac aaatgggttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cgcttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggcggggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagatcaag
     1381 aaggagctca atcaagtcgt atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt ttactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagaca
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttattttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgacca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgctgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagctgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaactagct gcaggctgct caaaacactg ttttgaggtt gcagatggaa
     3781 gctgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
     3841 catagtatca agggttttca acacttgata ctatgcgttt tctgatgtta aagactttct
     3901 accagttttt tttaagcata attgttagtt gtagtcattt attattcttc aaagaaaaat
     3961 ggtggggcga attttttcag ttcttcaaag cacttttgag cagtatctgc atcttcacag
     4021 atgataagac agacatcatt accacaaagg gtagcgatag cgtcagggaa gctcaaagta
     4081 tcaatgatag aaccaaagga ttgagccagt ccaggaaggg tttttagtag gacttggtgt
     4141 tgaactgggc gcatccagac aagggcgtct tccatgtaga gttcgagacg tttttcccat
     4201 tttgagatgg aaccattgtt aagaacataa taagcgctat cttcttcgcg gacttttgat
     4261 aggttcatat ttttgatgtc gcgtgagagg gttgcctggg ttacttgaat gtcgttctta
     4321 gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt
     4381 ataagttggt ggcggtgttc tgatttattc ataataatgt aactcctttt agcaaggtaa
     4441 ggtaagcatg gactgagcga ggtcgacagt caagtggtag tctgtattgt cacggatggt
     4501 gatttcaaag tcagtagtat agaggactaa acggagagtg tctccttctt ttagcttgta
     4561 aatagttggc tgcagttcaa attgaacatc catccattca tctgcagtaa tatcctctac
     4621 taacagtaaa tcatttctat tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc
     4681 ctctggtcta aatggcaatt cacagagatt ttccaacatg tgatagcgac cgttgtcaat
     4741 ggttctagca cttaaaatag ctggataagg ttgtaggtat ttcttttgcc caaattctag
     4801 cagttgggca gataagagcc ccttgtttgt actggatttg atacgaagat tgagctgagc
     4861 gcgaccgttt aggtggagat ctttagtcac aggaaggtta atagtaatct gattagcttt
     4921 cccttgatag agctctgtat tgaaggtttg gtatgtctta ctatagcgct caaaatcctt
     4981 atctgggtac tggttttgaa tagcttgctc ttcttgacca agtgagaagg ttttacagtt
     5041 ttcttgccca ccgaagttat caagtgataa ccaagtctgt ggagctgtat tgtcctgcca
     5101 gataacagta ggaagttgaa agtctgtttc ctgtcctagt aatttcttgg ttaataaggc
     5161 atttatggac tcacggaagt caattgattg ccaattgttc atgtaaacat gggcaccatt
     5221 atggaaaaag agatgcttgt gtatatgagt aggaagagca tggaacatct ggtaaacatg
     5281 aagtggtttg acattccaat cctgagaacc atgagtaaag acaacctctg cctttacttt
     5341 atgggcattg agcagataat tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg
     5401 gtctagctga gctttcactt tttctaagtc agcttggtga gcttcattgc cacggatata
     5461 gtcgccagct aagagattac gagaataggt taactcagca agggagtcaa agtcctcacc
     5521 tggataacca cctgggctag tcaccagacc gttttcacgg tagtagttgt accatgatga
     5581 aattcctgcc tcggcaatga taacttctaa accatcgact cctgtagtcg caagaccatt
     5641 ggacatggta cctagatagg aaagtcccgt tgtagcaact tttccgtttg accaatcagc
     5701 cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg caacggccgt taagccaatc
     5761 gatgacattt ttataagcct cgatttgctg gtagtctcca ttagtcatga aacctgtcga
     5821 gtctttggta ccaacacctg agacatagag attggcaaag cctctcggaa ggaagtagtc
     5881 gtttagtgta tagctagagt tgatgtgagt tagcttttcc tcagcctctg ctacaagctc
     5941 agcttgacct tggggttgga cgagatttag ttgaggttcc tctagctcaa tcttgtgagg
     6001 aagcttaacc tcaagctcaa cctccatctt gtagagagcc ttgtcactag ccttgtcatt
     6061 ggttccctga tgataagggc tggctgtcat gatggcaggg atttttccat caaaacgagg
     6121 gcgaataatg ctaaccttta ctaggtctga tagccctttt tggtcagtat cgacacgaga
     6181 ctcaacgtaa acgacttcac gaatgacatc ctggttagaa aaagtagcca aactcttgcc
     6241 gttaaagtag tggtagtcat tatcctccgg aataagacca tcactaacaa gttggtcgat
     6301 aagagtattt ccttttttgg tgcgagtatt gagtaactga tagagatttt caatcaagtc
     6361 accatatata atgggaaatc cagtttcttt acgaaaaacg tcactatctt cgaagtcaac
     6421 caaataagaa aagcctaaaa gttgaaaagc aacagtataa aaaatatctg ctgtcagttc
     6481 atcttctgat tgaaaaaatg tcagcaggtc tgttttttta tcagctgcta ggatagaaag
     6541 tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc
     6601 tttgtgattg gctgtatttt gtaaatcaaa gccacatttt tttagctcag ataagacatt
     6661 ttcttttgga aaattgatat aactatattg attaaaacgc atagaacctc catatagaat
     6721 gacagttaag gttattatat caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga
     6781 aataatccaa taaaaatgaa taaagtacta aattcaatat agagaacaga gtaacaataa
     6841 gaataataga tagggtataa aagttctagg agatttatat tatatgcttt ctatttttat
     6901 atacaatata gtataaatat aaaaacgatg acaaaaatac aaatgaatag aaaataaatt
     6961 agtaagctga tgaaattttt ctcaagagaa gctatttata ggtgaaaatg gtataatata
     7021 gtgagaagga tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat
     7081 agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc
     7141 tacactcatt tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagag
     7201 attacaaaaa aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat
     7261 gatcaggaag tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg
     7321 aagctttcga cagccaagat gcagggggtg aaaacttggt cagtcctgtc ccagtacctg
     7381 gaggatatcg cggtcattgt gccttatttt gatagagttg agtcgttaga actaggctgt
     7441 gattactata taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta
     7501 cctctttatc gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca
     7561 gcgattaaag aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt
     7621 atatcagcaa gttctttaga gaaactattc caagagtgtt ttccgcaagc tttggacaat
     7681 ttagaaaagc ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt
     7741 tttaatccag ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt
     7801 cagaaggggt tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt
     7861 catgatatgg gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga
     7921 tcgaatggct attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat
     7981 gccttagaca tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt
     8041 aatcgtgaac gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca
     8101 gattttatca gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact
     8161 ttttcaacct ttggagccaa gcaagctctt cgagatgttt tgaaacgctt tggtgtgcca
     8221 gagtatgaat tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc
     8281 tatgagggca atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct
     8341 tttgagattg cttgcaagat agagggctat ccaaggcaaa cctctgtcca tgcggctggt
     8401 gttgtaatta gtgaccaaga tttaaccaac tacattcctc taaagtatgg tgatgaaatt
     8461 ccactgactc agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt
     8521 ctgggactac gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaacagaa
     8581 ggtattcatc tgaaaattga agaaatcgat ttagaagaca aagaaacgtt agctttattt
     8641 gcctctggta atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt
     8701 aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg
     8761 ggtgctagtg actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact
     8821 gttctggatc cagtactgga ggatattttg gctccaacct acggcataat gctctatcag
     8881 gagcaggtta tgcaggttgc ccagcgattt gccggattta gtcttgggaa agccgatatt
     8941 ttgcgtcggg ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggcttccttt
     9001 attcaaggtt cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt
     9061 atggagaagt ttgcaggcta tggttttaac aggtcacacg cctatgccta ctcagcattg
     9121 gccttccagt tggcttattt taaaacacat tatccagcca tattttatca gattatgtta
     9181 aattcttcca acagtgatta cttaatagat gcacttgaag caggttttga agtagcctct
     9241 ctatccatca acaccattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt
     9301 ttgaaatcca ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct
     9361 tattctaaca ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg
     9421 ctagaacctt tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta
     9481 tttaataact tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat
     9541 gctatttata gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa
     9601 caagagcttt tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct
     9661 atttacccga ttaccccaat cggaaatttg tcagaaaata gctatgctat tatcttggtt
     9721 gaagttcaga aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag
     9781 gcagatgata gtaagaaaaa attggatgtc actctctttt cagacttata tcgtcaggtt
     9841 ggacaggaaa taaaagaggg agccttctac tatgtaaaag gaaaaataca attacgtgat
     9901 ggccgtctgc aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggatt
     9961 caggttaaaa atcatgactc ggatcaagag atgtcacgta ttttagacca gtataaaggc
    10021 ccaatcccag tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat
    10081 tttgtagcta aatctgatga attagaggcg aaattgaatg gaatagttat gaaaacgatt
    10141 tatcgctaaa attacggaaa atagaagaat tttcaacgta aatgtggtat aatcagtaag
    10201 aatgttaaaa gaaaaaggag cataaccaat atgaaacgta ttgctgtttt gactagtggt
    10261 ggagacgccc ctggtatgaa cgctgccatc cgtgcagttg ttcgtcaagc aatttcagaa
    10321 ggaatggaag tgtttggtat ctatgacgga tatgctggta tggttgccgg tgaaattcat
    10381 cccctagatg cagcttcagt aggggacatc atttctcgtg gtggtacttt ccttcactca
    10441 gctcgttacc cagagttcgc tcaacttgaa gggcaactta aagggattga gcaattgaaa
    10501 aaacacggaa ttgaaggtgt agttgttatc ggtggtgacg gatcttacca cggcgctatg
    10561 cgtttgactg aacatggctt cccagctatt ggtcttccag gtacaatcga taacgatatc
    10621 gttggtactg actttacaat cggttttgac acagcggtta ctactgccat ggacgctatc
    10681 gataagattc gtgatacatc atcaagtcac cgtcgtactt ttgtaatcga agttatggga
    10741 cgtaacgctg gtgatatcgc tctttgggct ggtattgcaa ctggtgctga tgaaatcatc
    10801 atccctgaag caggcttcaa gatggaagat atcgtagcaa gcatcaaagc tggttatgaa
    10861 tgtggtaaaa aacacaatat catcgtctta gctgaaggtg tgatgtcagc ggctgaattt
    10921 ggtcaaaaac ttaaagaagc tggagataca agcgaccttc gtgtaacaga acttggacat
    10981 attcaacgtg gtggttctcc aactgcgcgt gaccgtgttt tggcgtcacg tatgggtgca
    11041 catgctgtta aacttcttaa agaaggtatc ggtggtgttg cggttggtat tcgtaacgaa
    11101 aaaatggttg aaaatccaat tcttggtact gcagaagaag gggcattgtt tagccttact
    11161 gcagaaggta agattgtggt taacaacccg cacaaagccg atattgagct atctagcttg
    11221 aataagagct tgtcataatt tacaatttag ttaataagac caaaaaggtc atatataaag
    11281 gagtcacaaa aatcatgaac aaacgtgtaa agatcgttgc aactttgggt cctgcggtag
    11341 aaatccgtgg tggtaaaaaa ttcggtgagg acggatactg gggtgaaaaa cttgatgttg
    11401 aagcttcagc taaaaacatt gctaaattga ttgaagctgg tgctaacaca ttccgattca
    11461 acttctcaca cggcgaccac caagaacaag gtgagcgtat ggcaactgtt aaacttgcgg
    11521 aaaaaattgc aggtaaaaaa gttggtttcc ttcttgatac aaaaggacct gaaatccgta
    11581 cagaattgtt cgaaggtgaa gctaaagaat attcatacaa aactggtgaa aaaattcgtg
    11641 ttgcaactaa acaaggaatc aaatcaactc gtgaagtgat tgcgttgaac gttgctggtg
    11701 ctcttgatat ctatgatgat gttgaagttg gtcgtcaagt tttggttgac gatggtaaac
    11761 ttggtcttcg tgtggttgct aaagatgatg caactcgtga atttgaagtt gaagttgaaa
    11821 acgatggtat catcgctaaa caaaaaggtg tgaacatccc taacactaaa attcctttcc
    11881 cagctcttgc tgaacgcgat aacgacgata tccgtttcgg tcttgaacaa ggtatcaact
    11941 tcatcgcaat ttcattcgta cgtactgcaa aagatgtgaa cgaagttcgt gcaatctgtg
    12001 aagaaactgg aaacggacat gttcaattgt tcgctaaaat cgaaaaccaa caaggtatcg
    12061 ataacttaga cgaaatcatc gaagcagctg atggtattat gattgctcgt ggtgatatgg
    12121 gtatcgaagt accgttcgaa atggttccag tttatcaaaa aatgattatc aagaaagtca
    12181 atgctgcagg taaagttgtt atcactgcaa caaacatgct tgaaacaatg actgaaaaac
    12241 cacgtgcaac tcgttcagaa gtatcagacg tattcaacgc tgttatcgac ggaactgacg
    12301 ctacaatgct gtcaggcgag tctgcaaacg gtaaataccc actcgagtca gtaactacaa
    12361 tggctacaat cgacaagaac gctcaagctc ttcttaatga atacggacgt cttgattcag
    12421 attcatttga gcgtaactct aagacagaag taatggcttc tgctgttaaa gatgctacta
    12481 actcaatgga tatcaaattg gttgtaactc ttactaagac aggtcatact gcacgtttga
    12541 tttctaaata ccgtccaaat gctgacatct tagcattgac atttgacgaa ttgacagaac
    12601 gtggcttgat gttgaactgg ggtgttatcc caatgttgac agatgctcca tcttcaactg
    12661 acgatatgtt cgaaatcgct gaacgtaaag cgatagaagc aggtctcgtt gagtcaggcg
    12721 atgatatcgt tatcgttgct ggtgtgccag taggagaagc tgttcgcaca aacacaatgc
    12781 gtatccgcac agtacgttaa gaaaaatata aaaacctatc atatccagct ttagagcttg
    12841 tgtgataggc tttttgtata gagggtaaga aataggcaaa actttcataa tggattgata
    12901 ctcttcgaaa atcaaattca aaccacgtca gcgtcgcctt accgtatata tgttactgac
    12961 ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacctgcgg ctagcttcct
    13021 agtttgctct ttgattttca ttgagtatga aataagatat gcacaaattg attaggaaat
    13081 tcaaatgaat ttctacaaat gttttagcaa tcgtaatgta cttgtctaga ttcgatctga
    13141 tatattttcg atttaatgat atggtattta aaacctccaa agtagcttgc tccattcttt
    13201 tacttacgtg agtgtagatg ttatttactg ttttagcgtt tttgtgttcc actctaacca
    13261 ttatagcatt cttctcagct agtgtactaa ggagtgtgtg cctgaaaata tgggaactaa
    13321 ggggctggtt tatcggtttc tctagtttag tatttgcctt ttgcaaagtg atcttaaatg
    13381 cctttctcta aatttacata tcactattgt ttaacaaaat ctaatctatt ttaggtcact
    13441 tattcttttt ttgaaatgta gaatgaactt tttcaaagtt tttcgaatct tttaaaatct
    13501 gtttgtttta tatcgccatt ctcccccttt tttaattctc cctatatagc ctgacaactt
    13561 tcccgatggt acgaatatgg ttgctttcgt ctaggtggat gtcggagtat tcgggattga
    13621 gtttttttga ggtagccttg gcggagtttc ttgacatagt tagtgccgtc tacttggaag
    13681 atgccgatgg tattatagtc aatctgtggg gtattcttga taaataggta gtcgctgttt
    13741 cttatctttg gctccatgga cttgctgacg acataagcga ttgggtcgta gtcgtctggg
    13801 ataatggaaa ctccataact aaatcgtcgt cctgcatcaa gcggctacct gcagagataa
    13861 actacctaac acgagagtaa gtagtctgtc tgtagtcgtc cagtctgatg atttttacga
    13921 tacttcgttt ttctgatcat acagttgcct ctcggcatag gtcagaactt taccttgtct
    13981 gggtggtgcc cgttggtcgt agatagattg gatatcgcta ggagaatcct tttgaactgg
    14041 aggaaagagg gcatcaatca agctactgaa tactttaact aagtcaaata tagtattttt
    14101 cttagtagac ctaacccttt tttcataatt tccaatggtg tttttactta taccaatctt
    14161 agtacccaat tcttattgag tccaaccatt actagtctat attgttttat agttgattga
    14221 gtttggaata gtacgctgta gctgctaaaa catttctagg aattaatttg cctttcctaa
    14281 tagagttgtt catatcttat ttcaatctac tatatttttc gcctctaaca atcgcaatct
    14341 cttctttatc tacgaatgaa atcgctttct atttttgtaa gtaaagcatc acacgaaatc
    14401 cacgaaaatg aaaacctttg ttgtgttttc gtaaaaaatt tgttgacaga gcacgaaacg
    14461 cctactataa ttaaatcaag cttaaggaaa taacaaaaaa acaaatcgga gggaaagacg
    14521 atgaacatat taaatgagaa agtaatcaat atctgtaaag cagtagttaa agaaacttta
    14581 atccaagaca tttaggagaa agaaatgaag aaatcaagaa aattagccac attaggaatc
    14641 tgttcagctt tgtttttagg cttggctgct tgtcaacaac aacatgctac ttctgagggg
    14701 acgaatcaaa ggcaaagcag ttcagcgaaa gttccatgga aagcttcata caccaaccta
    14761 aacaaccagg taagtacaga agaggtcaaa tctctcttat cagctcactt ggatccaaat
    14821 agtgttgatg cattttttaa tctcgttaat gactataata ccattgtcgg ctcaactggc
    14881 ttatcaggag atttcacttc ctttactcac accgaatacg atgttgagaa aatcagtcat
    14941 ctctggaatc aaaagaaggg cgattttgtt gggaccaact gccgtatcaa tagttattgt
    15001 cttttgaaaa attcagtcac cattccaaag cttgaaaaga atgaccagtt gcttttccta
    15061 gataatgatg cgattgataa aggaaaggtc tttgattcac aagataagga agagtttgat
    15121 attctatttt cgagagttcc aactgaggca actacagatg tcaaggttca cgctgaaaag
    15181 atggaaacat tcttctcaca atttcaattc aatgaaaaag ctcgaatgct gtctgtagtc
    15241 ttgcacgaca atctggatgg cgagtatctg tttgtaggcc acgttggggt cttagtacct
    15301 gctgatgacg gtttcttatt tgtagagaaa ttgactttcg aagagcccta ccaagcgatt
    15361 aaatttgcta gtaaggaaga ttgctacaag tatttggaca ccaagtatgc ggattataca
    15421 ggcgagggac tggctaagcc ttttatcatg gataatgata agtgggttaa actttaatag
    15481 tgttatgata tgacagtaat cttaggattt ttatttctat ttttgatgag ttggtgggtt
    15541 atttcaatcg ttaatagcca gaaaccacgc aaaaatgaaa catttattgg ctatgtccaa
    15601 agatacgata ttgatgggaa tggctatcaa tcattaccgt gtcctcagaa ctgagaggag
    15661 ttcttgaaat cgtaaaacca ctttgaacaa gagttacttc aacccattgg ctccgacgga
    15721 ttaagttgct ttcgtgaata ccaaaatcag ccgcaatttc ttcataagtg cggtattctc
    15781 gcacatattg aaagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccacc
    15841 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtcgt
    15901 gcgctgaaca ccaacaagac gcttaaatcg tgcatcagtt agttgtttac ttgcttcata
    15961 attcatagaa ctattatacc atgttttgtt tcgcaggaaa tctaatgcta aaatcttatc
    16021 agtgagaaga tttcttaaag tttattcttt gtagtttcat ctgtattagt acataattta
    16081 acttagagaa aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca
    16141 ggaaatgatt aagaaaaggc ttacaatgtc taatattagt gacaaagaaa ctactgagaa
    16201 gattctggcg ctagtaccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca
    16261 tgctacaaca cgtacgatta aacgcatttc aattgaatac cctgaactct acgctgtagc
    16321 tcaaacaagt ggtgagattc cagaaaaaga acgcgaagaa ttgcgtcaga ttatcacgac
    16381 tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat
    16441 tagcggtttg ggaagcaatg cctatcatag caaggatttt tttcaagaac tagattcgca
    16501 ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg
    16561 gtttaaaaat gagattgtag aggaagaatc tatctgtctg ataggccatt ctcttggagg
    16621 agatttagct cgttatttcg catcggaatt tgaagaagta aagaaactga ttcttttgga
    16681 tggtggctat ctagatttag ataagatttt acctttggat acagagttag aggaaactaa
    16741 aaattatatc aaatctcaaa ttgtttcgga cttagctctt cttatttcta aagagaagtc
    16801 cgaagcaaag cattggtcag aaaatatgga gaaagctgta agacagtcct atcactggaa
    16861 tgttgagtat aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg
    16921 cctacggaga aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc
    16981 tcgctatcct aatggagcta catggagaga ggaagcccta aaagaattgc cagactattt
    17041 taatactatt tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat
    17101 cgctagtcta atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa
    17161 tggtataaga tgaaaatcta caagtcacta attttcatat aacaaaaaaa cgaacaggct
    17221 ctttttctgt tattcagaag agaacttgtt cgtttttatc ttgatttttt taaaaagctc
    17281 tatatacata gggattttct ggtttatcga ctttggtaaa gctgtcgatt tccaaggttg
    17341 gaaggttttg tttgagttct ttatggtagt gattgaccag ttttcctttg gctgtaatcc
    17401 aggtgttgtt ttcatactgc cgggtattgc ccttggtcag caatccatag acaccagaat
    17461 ctgcgataca gtggataatg ccgaatcgga acagaaattg actattggca tgactggggt
    17521 cgttatagac aaagcctgta aactggattg tcttgccctc aaattcatct ggatagtcgt
    17581 agatagcctc catgacttcc atatagtttt cattagtgat ctgaatacta tcttgggata
    17641 agtatttatc cgccgccgtt cgcatttcct tttcataggc tgattttgaa aaataagaac
    17701 tagtatctgg tttcaaatat tggcttgtcg tcccttcact tgtctgaata gctagatccg
    17761 ttccttccga tagggggaaa tgataacctt tagcagaaac ggtctgagaa tccaagctaa
    17821 cagttgggaa agttaagccg atgacaagtg gaatagccag aagagaaata ctcgtcatct
    17881 tggccaatcg gctgttcaga tgactgtggg ttttgacttg cttcatccag atatacaatt
    17941 gaacaattgc caagataaag gaaagcacca tggagatata ggccagatag gaatagtgca
    18001 tgttgatgta ctggtttagt ttgcccgaca gatggaggta aatagtcagt tcaaaatagc
    18061 cagctaaaac taaaaatcga atcataggat gactccaatc aagagagaat aggctaaaac
    18121 gaccagagtc acaatcgtaa tgaagtgact aataaatcgt gctttcaagt aatttttcat
    18181 catgagaata tttttgatat ccagcattgg gccaatgacg agaaaggcca gaactggtgc
    18241 caaaccgaaa ctcgagagta gagaagcacc tataaaggca tccgcctcac tacagagcga
    18301 aagaagaaag gctaaaagca tcaagagcag gatagcaaaa agaggagtcg cactgataga
    18361 ggtcagaatc cgagtcggaa cgtagacctg tattatagaa gcaaagaggc agccaaatac
    18421 caaataacgc cccgtatcaa aaaattcatc aatggcctgc acaaagactt gaaaaacttt
    18481 ttttgcagaa ctcaagtaag aaaaatcatg ctcatgacaa gccagacgat tttctttctg
    18541 aatcggttct tgccagaaaa atcctagaaa aattcctagt attacagcca caagaatgga
    18601 acccagagct cgtaatagtg cgacatggaa ggagttgcca aaggcagaat aggtcgcaaa
    18661 aagaacaatg ggattgataa caggtgctgt cacaagaaaa ggaacggccg tgtaacttgg
    18721 aacctttttt tccagaaaac gattgatgat ggggacgatt ccacattcac aagaagggaa
    18781 aagtataccg acaaaggtcc caaaaaagat tctcccccaa cgatttcgag ggagaaaatg
    18841 ataaaccttg tcaggtgtga tataaacttc aatcagccct gagacaatgc ttcctatcag
    18901 aacgaaggga agggcttcaa tgataatgga gagaaaaatg gctccagttt gaagtacact
    18961 agatgggagt tgttgaaaag cagtcatcta gtttttcttt tctgctttga cttttttctc
    19021 tttgtcatca gggaaagtaa cttgtttcaa atcagggagt ttagcaaact cttcaaacat
    19081 cttgtccaag tcgtctcgtt ttgtaaattt tacagccata ggtgtacctc gattctaaat
    19141 tctacctcta ttatactatt attttgcgga aaagggagtt ttttaatttg ttttcgatag
    19201 ttgatactct tcgaaaatct cttcaaacca cgtcagcttc gccttaccgt agta
//
LOCUS       DBEJNA010000040        18896 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEJNA010000040 DBEJNA010000000
VERSION     DBEJNA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.40"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            174..512
                     /locus_tag="ACL3JB_001710"
     CDS             174..512
                     /locus_tag="ACL3JB_001710"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGR0686403.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            702..2138
                     /locus_tag="ACL3JB_001711"
     CDS             702..2138
                     /locus_tag="ACL3JB_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0686404.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWKWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMIHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2190..2429
                     /locus_tag="ACL3JB_001712"
     CDS             2190..2429
                     /locus_tag="ACL3JB_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGR0686405.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2559..2873
                     /locus_tag="ACL3JB_001713"
     CDS             2559..2873
                     /locus_tag="ACL3JB_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGR0686406.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2991..4970
                     /locus_tag="ACL3JB_001714"
     CDS             2991..4970
                     /locus_tag="ACL3JB_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0686407.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLLKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQSFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            4980..5294
                     /locus_tag="ACL3JB_001715"
     CDS             4980..5294
                     /locus_tag="ACL3JB_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGR0686408.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5325..5831
                     /locus_tag="ACL3JB_001716"
     CDS             5325..5831
                     /locus_tag="ACL3JB_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686409.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5911..7257
                     /gene="celB"
                     /locus_tag="ACL3JB_001717"
     CDS             5911..7257
                     /gene="celB"
                     /locus_tag="ACL3JB_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGR0686410.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7636..7812
                     /locus_tag="ACL3JB_001718"
     CDS             7636..7812
                     /locus_tag="ACL3JB_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686411.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8214..10427
                     /locus_tag="ACL3JB_001719"
     CDS             8214..10427
                     /locus_tag="ACL3JB_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR0686412.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10649..11125)
                     /locus_tag="ACL3JB_001720"
     CDS             complement(10649..11125)
                     /locus_tag="ACL3JB_001720"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0686413.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11348..14548
                     /locus_tag="ACL3JB_001721"
     CDS             11348..14548
                     /locus_tag="ACL3JB_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0686414.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     LHKYVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVEQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKHGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14928..15304
                     /gene="tnpA"
                     /locus_tag="ACL3JB_001722"
                     /pseudo
     CDS             14928..15304
                     /gene="tnpA"
                     /locus_tag="ACL3JB_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            15486..15548
                     /locus_tag="ACL3JB_001723"
                     /pseudo
     CDS             15486..15548
                     /locus_tag="ACL3JB_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15692..16321)
                     /locus_tag="ACL3JB_001724"
     CDS             complement(15692..16321)
                     /locus_tag="ACL3JB_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGR0686415.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16331..17332)
                     /locus_tag="ACL3JB_001725"
     CDS             complement(16331..17332)
                     /locus_tag="ACL3JB_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0686416.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17363..18004)
                     /locus_tag="ACL3JB_001726"
     CDS             complement(17363..18004)
                     /locus_tag="ACL3JB_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0686417.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18023..18838)
                     /locus_tag="ACL3JB_001727"
     CDS             complement(18023..18838)
                     /locus_tag="ACL3JB_001727"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0686418.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6103 a         2967 c         3931 g         5895 t
ORIGIN      
        1 tgctcttgtt tcaattgact ataaatcgct ataagaaaaa atcattttat tggtataaag
       61 aagtgattga aagtaatggc gaaacgttag ataattagtt cataaaaaac aagtttagat
      121 cctcatctaa acttgttttt ttaaaattga aggatgattt tggaggatat aagatgacat
      181 tgactattca tgtatattat aaaggtgatg gagatagtgc aataaagttt gcaagagaaa
      241 tgcttgatag tggccttgtt gaagaaatta gaaatcaaaa aggtaacttg aaatacgaat
      301 attttttacc aattgaaaaa gagggaacta ttctccttat tgatcagtgg ataaatcaag
      361 aagctttaga tgaacatcat caatcaaaga caatgcagaa aatcttagat ttaagaaaaa
      421 aatatcactt gcagatgcaa gttgaacgtt atatagaaga tgattctggg atgccagaaa
      481 gcgataagtc gtttatagac acagggaatt agaattattg tgagagtttt tgtagtttga
      541 aagtattgaa aatcgtaaag atatcattac gagaatacaa gaagatattg ttctatttcc
      601 attaaaaatt acttctttcc ttaacaataa ggaaaaagaa tgcgttttca tcttttgatt
      661 tgaggtttat aataagagta tcaaagtcag gaggaaaaaa gatgactact tttaaagatg
      721 gatttttatg gggtggtgct gttgctgctc atcaacttga aggtggatgg caagaaggtg
      781 gcaagggaat tagtgttgct gatgttatga ctgctggtcg tcatggagta gctcgtgaaa
      841 ttactttggg agttttagag ggtaaatatt atccaaatca tgaggcgata gatttttatc
      901 atcgttataa agaagacata gcactttttg ctgaaatggg attcaagtgc ttccgtacct
      961 ctcttgcatg gacacgtatc tttccaaaag gtgatgagtt agagccgaat gaagaaggat
     1021 tacagtttta tgataatctt tttgatgaat gcttaaagaa tggtattgaa cctgtcatca
     1081 ctctatctca ttttgaaatg ccttatcact tagtgaccga atatggtggt tggaaaaata
     1141 ggaaattgat tgatttcttt gctcgttttg cagaagtcgt atttaaacgt tacaaagata
     1201 aggttaaata ttggatgact ttcaatgaaa tcaataatca agcgaattat caggaagatt
     1261 ttgcaccatt tactaactca ggtattgtat atgaggaagg tgataataga gaggcaatta
     1321 tgtatcaagc agcacattac gaattagttg cttctgcacg agctgtaaaa attggtcatg
     1381 agattaatcc agattttcaa ataggttgta tgattgcgat gtgtccaatt tatccagtta
     1441 cttgcaatcc taaggatatc ttaatggcaa tgaaagctat gcagaagcgt tattattttg
     1501 ctgatgtgca tgttttaggt aaatatcctg agcatatttt caagtattgg gaacgaaaag
     1561 gtatttcagt tgattttact gaccaggata aagaagattt acttggtggg actgtagatt
     1621 acattggttt cagttactat atgtcctttg ctatagactc tcatcgtgaa aataatcctt
     1681 attttgatta tcttgaaaca gaagatttag tgaaaaataa ttatgttaag gcttctgaat
     1741 ggaagtggca aattgatcca gaaggtttgc gttatgcgtt aaattggttt acagaccact
     1801 atcacttacc actctttatt gttgaaaatg gttttggagc tatagatcaa gttgcagcag
     1861 atggtatgat acatgatgat tatagaattg aatatctagg tgcccatatt cgtgaaatga
     1921 aaaaggctgt agttgaagat ggtgttgatt taatgggtta tactccatgg ggatgtattg
     1981 atttggtttc agctggtacc ggtgaaatgc ggaaacgtta tggctttatt tatgtagata
     2041 aagatgataa tgggaaggga agttataatc gttccccgaa aaaatctttt ggctggtata
     2101 aggaagttat ttcatctaac ggtgaatcag tagaatagta taaacaaact gagattattc
     2161 tcagtttgtt tagcatattg gggtgacata tgattggaag tattgcagca attttaacaa
     2221 catttgcatt tttaccacaa gtttttcgtg tagttaagac aaaggacaca ggatctattg
     2281 ctctaggtat gtatgttatg caagttattg gtattgcatt gtggcttgct catggtattc
     2341 gtataggaga cttgcctttg attttagcaa atagtgtttc atttctactc tcaggaataa
     2401 ttttatttta taaattgaag tataaataat ttttttccat atcatttagg aaaatgaggg
     2461 aattgtcatt ggaaacgctt tattttataa taaaaataga taacaaataa gccaacttag
     2521 cacagctttg attggattta agaaaaggag aaaatattat ggcaaaagct ttaattattt
     2581 gtgcagcagg aatgtcttca tcacttatgg cacagaaaac aacagagttt ctaaaaggaa
     2641 aagggaaaga tattgtagtt gatgctatta gtgctactga aggagggaaa gctatcgcag
     2701 cagcagcttt tgatttgtat cttgtcagtc ctcaaacaaa aatgtacttt aagcaatttg
     2761 aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat acctcctcaa gcctatattc
     2821 ctattccaat gggaattgaa aaaatggcta atttgattct tgagaatatt tgatgaacac
     2881 atgaaatgtc aataaatatt taagttaaga taaattgttt tgagtttgat ataaattgat
     2941 ttaagtgtat aatatgcttc aatatatgaa aacatacgtt ttaggaggga atgaatgtgt
     3001 taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa cgttttgtta
     3061 caagcaaaga actggcagaa tatttatcct gttcagatag aactgtccgt aatgtactga
     3121 aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa caaggtcaag
     3181 ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa acttatgaac
     3241 tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta gtatttatct
     3301 taaataaatt attatttgag caagttccag ttctttttga tgatttagct gatgaacttt
     3361 acgttagccg ttcaacatta tctcatgatt tcagaaagat acgagtgatg ttatcagagt
     3421 ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc gaggaacgtg
     3481 ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa acaatacatt
     3541 gctatgtaaa atttaacttt tttgatcaaa ctgttccatt agaagaattt gctagaattg
     3601 ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta cagaatttag
     3661 tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata aaaaatatag
     3721 actgtcagat gactgatgat gcaatagaga gaaaggttgc ccaaagaatt ctttctaaag
     3781 taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt actttgcatt
     3841 tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa gaagttttaa
     3901 aaaaatcttt acttaaaaca tttcagaatt taggattaga tgatatgtat aacttttctt
     3961 cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa gtacgtttag
     4021 aaagccggat taccttaaat aaccctttgg tagatgaaat taaacagaat tatagtgata
     4081 tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag tggacaatat
     4141 cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa cgtagcaaag
     4201 agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca gcccaaatgt
     4261 taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat gtaataggct
     4321 attatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca gctgttgatt
     4381 tatcaaatct atattttcaa atcccagttt ttaaagttag tgtgtttctt aagagtgatg
     4441 agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat gtacaatcat
     4501 caaagattaa caaatttgaa aacaacggct ttagacagta ttttagtaaa gaaaactttt
     4561 taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag agtttatctg
     4621 ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag cgcgaagaat
     4681 taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag tcctttggta
     4741 cagagggaaa ggtttcggtt gcaatttgta aagattcgtt actctgggat aatcaaagtt
     4801 cacatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa ggtttggcaa
     4861 ctgtgactaa aaagatagtc tctctgacag agaatgatga attgcaaaat cagctaatat
     4921 cttgcaataa ctttgaagat tttattaaca tatttgagaa gataaaatag gaggttcata
     4981 tgaatcaaga ggaactgcag gttgcagcat ttgaaattat cctgcattcg ggaaatgcaa
     5041 ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat gatgcagaaa
     5101 gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa accaaactct
     5161 tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta catgctcaag
     5221 atcatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta gctctttata
     5281 agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat aaaaaagaac
     5341 gacaaaagat tgaacaacaa cgtcgagaga tggctctaac taatactttt ttcaatcgat
     5401 atcttcttct acgttattca atagcactct tcttttttgg gaatatttat tggcttttga
     5461 gtcagtttat tagtccctcg cctattatta ttttccccat tatgctcata gtattttcta
     5521 ttttagcaac tgttgaacaa tttaaactct atggaaatag gaaagaaaag ttgggaataa
     5581 cactaatgtt tgttagaata caaatgctta tttcaatagg attacttgtt ttaacttgga
     5641 caagttggtt taagaatctt tttccgattt ttgaaaataa ccaagtagca cgtttatttg
     5701 tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga agaattaaaa
     5761 aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa aagaactcac
     5821 ttagtttata atcctgatct agtataattt gtatttgaaa ctagtcttta gaaagtaaaa
     5881 attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt gtttggtttt
     5941 cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt agtacgtgct
     6001 atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat gtttttggta
     6061 ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat tttctctgct
     6121 tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat gggttctcta
     6181 tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc agaggaggaa
     6241 gaactcaata tgaatcctct taatggtgcc ttgcttgcct tgatggcttt tgtcatgaca
     6301 gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct aaaagaagga
     6361 gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg gacaacaggg
     6421 atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat gtgtgttaaa
     6481 cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg tggatttacc
     6541 gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg tcttcttgta
     6601 gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt atccaatctg
     6661 actaattcgt ggattggttt aatgattatt tatctattga ctcaactact ttggattgta
     6721 ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct tgctaacatg
     6781 gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa tatgtttgta
     6841 attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt tgcctctaaa
     6901 tctgaacagc ttaaagcaat aggacgagca tctgtagttc cagccttatt taatattaat
     6961 gaaccattaa tttttggatt acctattatc tataatccag ccttggctat accatttatt
     7021 ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa ctttattaag
     7081 ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt cttagggaca
     7141 gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt cttagtctat
     7201 cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg tatctaataa
     7261 gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagcg ttaacattag
     7321 cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt cgctatgtag
     7381 ggtatgaagc aaaatagaaa gtagttcgaa tagttgataa acagggaatt gctgttattt
     7441 aaaaaaacaa taaagtaaag tatgttatcg tagaatacga tacaatagta aaaaagcaaa
     7501 aagaatgcgt tttatatttg ggtttgaggt ttataaaata ggataagcgt gctgaaaact
     7561 tagatatgac aaacaaaata aaatttttaa aagctacaga gaaacatggt ataatgtatc
     7621 taaaggaggt agcatatgtc cttagatata gataaagaaa agatgacaat catgggaata
     7681 gcttttgaaa accgatccgt ttttaagagt gtttggtatg ctttaagtac aaatatgatt
     7741 gaaggatggc gacctacggt tagtgatgtt gaaaaattac gagatgaagc tcttgctctg
     7801 gggatgactt aatgaagcgc aactgttatg agtcttatga ctatgttgat ccggataatt
     7861 tatataccga tccgggttct tcagttctaa gaaataagca ggaaggaaaa aagcacgcga
     7921 gcttgaatat cgtatgattg ctagtaagag tttgaaatta tttatcaatc ctatcttagt
     7981 taatagttta aaagtagttt gtttcacaac tgcataagct tagaaaagtt gaaaagtgat
     8041 aactctttaa taaactcttg gtttgttaaa agatattttg tccactacat ttttttcaat
     8101 tgactattat ttgtcataga tataacagat agaacattgc attcagaata atgaaaaacg
     8161 catcaaaaat ggtgcgttct gtttttatgc taccataaaa ggaggaaaac aaattgaaaa
     8221 tttttaaggg agagttttat cgaatctctg tattaacaga caagctagta aggttagaat
     8281 actctcaaac tggaagtttt gaggatagaa cgacacaact tatctataat agagattttg
     8341 gccaaatttc gttagattat atcgagacat caaacgtact agatattatg acggactatt
     8401 ttcatctgca ctttaataaa ggagaattta acgccgaaaa tttatttata gaattaaaag
     8461 gaaattttgc cgtatatggt agtcgctggt attttggtga atctattgaa acgttaaaag
     8521 gaacagctcg gactctggat aaggcagatg gagcaatctc gttagaagat ggaattatta
     8581 gccgaaatgg tatagcctta ttggatgatt ctcaaggatt tatttgggat gaacaatctg
     8641 gttatattga gagagaaaat caaattgacc tgtatttctt tgcctatggg catgattata
     8701 gaggagcaat cagagatttt taccatttga ctggttcaac acccttgttg ccaagatatg
     8761 ctttaggcaa ttggtggagt agatattggc cttatacgtc ggatgaatac ttggatttaa
     8821 tagacagatt tgaaacagag aaaattccat tatctatcgg tgtgttagat atggattggc
     8881 atataactga cattccagct cgctttggaa gtggctggac aggatatagt tggaatagaa
     8941 acttaatacc aaatccagaa cagttattgc aacaacttca tgatagaaag ctaaaactct
     9001 ccttaaatgt ccatcctgct gatgggatac gggcttatga agaagcttat cctcaaatcg
     9061 caaaacggtt ggggttaaat gtagaactag aagaacctgc tatttttgat ttttttaatc
     9121 cctcttttag ggaagcctac tttaaagatg ttcattatga actagaaaag cagggagtag
     9181 atttttggtg gattgactgg caacaaggga cacaaggtat gctagatcca ctttggcttt
     9241 taaaccatta tcactatcag gatagttgta aaaatgcaga aggtggtttg attttatcaa
     9301 gatatgcagg tcctggtagt caccgctacc ctgttggttt ttcaggggat actattatta
     9361 gttggaattc cttaagattt caaccctatt ttacagcgac agcatctaat atcggttata
     9421 gttggtggag tcatgatatc ggtggacata tgttggggga ttatgacgaa gagctacaaa
     9481 ctagatggct acagtttggt gtttttagtc cgattactcg attacatagt tctagaagtc
     9541 cttttaatag taaagaacct tggttttttt cagaaacaac atctaagatt atgaagaaat
     9601 accttcgttt gagacatcag atgattccct atctatatac catgaatgta cagacacatg
     9661 aggaaggtgc cccattaatc agtccaatct attatttcta tccagagaat gatgagagct
     9721 ataatgttcc aaaccaatac ttttttggaa cagaactgat ggtggctccc attgtagaaa
     9781 agatggattt gacattccaa tctgcaaaag tagatgtatg gttccctgaa ggtgaatggt
     9841 atgacttctt ttcagagaaa aaatacacag gtggtgtgaa gttaagtgtt tatagggaca
     9901 tctcgactac gcctgtgttt gcaaaaagtg gtgcaatcat tcccttggtt ggttctgaga
     9961 taggtatggg tgttgattta cctgaagttg tagattggta tgtattccca ggaaaacaac
    10021 attcttttga aatgcttgaa gatcaaaatg gtcaaagata taaaacaaga ttatcaatcg
    10081 attgggaaat gggaatggta gagttagcat tacaaggaga ttctagtatc gttccaagca
    10141 atagaaaaca tagaattcat tttaaaggaa cgaatgtgtc tataattgaa ttgccaaata
    10201 agaatgatac agctaaattt gaatggaaag ataataaaag gacatcttta aatgacgaag
    10261 tttttagact actaaagaca gcttctcttc catatgaatt aaaagataga ttgttaaatc
    10321 aattcatcaa tgcgaaaaac tctcatgact taatgaatat cttgcatcat caggataagg
    10381 aattgagagg gcgtttgttg gaaatgatat ttactagcca aaactaattg aaataattag
    10441 aaagtcattt gtttagtgta tatgaagatt ctgtatggta ttcgttatca ctggtcacat
    10501 tgaaattgtg aaataagcac ctacaacata gactttacaa cacttcatgt ttcatatcat
    10561 ggggtgtttt tctatttaag tcaaagccca tcaaaaaatc tcactattca tcaggttaaa
    10621 ggaaacctaa tcatagtgag attgtgaatt atagtagagt ttgtatcgcc tcttcaattt
    10681 gttttgggtc tgtttttgaa gaaaagcgtt caaagacttg cccatctcga ccgatgagaa
    10741 acttagcgaa attccattcg actcgttttc ctagtgggcc ggatttctgg tcttgtaacc
    10801 agacatagag agggtctgct tccttaccgt tgaccttaat cttggcaaaa cgtgggaagg
    10861 tggtttgaaa atgtaggcta cagaaggcgt tgatttcctc tgcgctgccg ggtgcttgtc
    10921 ccataaactg attgcaaggg aaatccaata tttcgaagcc ctgatcttga tagcgttcat
    10981 agagttcttg aagtccctgg tactggggcg ttaaaccaca tccagtagca gtgttgacaa
    11041 tcaagagaac tttgccacga tagctatcca agggagttgc ttggttgttt tggttcaaaa
    11101 cggaaaaatc ataaagtgaa gtcatgaggg cctcttttct ttttctacat tgtaacagtt
    11161 tttacttttt tcgtcgagtc ggatggaaga tattgttgaa gaataagcct tcaatatgat
    11221 agaaaccgtt tacaaataac tttaaaaatg gtatgattta attaaaccgg tttacttagt
    11281 tgctataaat ctctaatttg agatttagtt cctattgatt ttacaatatg tttattggag
    11341 tgtatacatg caaacaaaaa caaagaagct cattgtgagt ttgtcttcac ttgttttatc
    11401 aggattttta ttaaaccatt atatgacaat tggagcggaa gaaacgacta cgaataccat
    11461 tcagcaaagc cagaaggaag ttcagtatca gcaaagggat acaaaaaatt tagttgaaaa
    11521 tggtgatttt ggtcagacgg aggacggaag cagtccgtgg acaggaagca aagctcaggg
    11581 gtggtcagct tgggtagacc agaagaatag tgcagatgcc tcaactcgag tcattgaggc
    11641 taaggatggg gctatcacta tctcaagcca tgagaaatta agggcagcgc ttcaccgtat
    11701 ggttcctatt gaagctaaga aaaagtataa actgcgtttc aagattaaaa cagataataa
    11761 aatcgggatt gccaaagttc gtatcattga ggaaagtggt aaggacaagc gattgtggaa
    11821 ttctgcaacg acgtcaggaa caaaggactg gcagaccatt gaagcagact atagcccgac
    11881 tttagatgtt gataaaatca agctggagtt attctatgaa acaggaactg ggactgtttc
    11941 ctttaaggat attgagctgg tagaggtagc agaccagctt tctgaggatt ctcaaacaga
    12001 taaacagctt gaggaaaaga ttgatttacc aattggaaaa aaacatgttt tttctcttgc
    12061 ggactatact tataaggtag aaaatcctga cgttgcttca gtcaaaaatg gaattttaga
    12121 acctcttaag gaagggacaa ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa
    12181 gattcctttg aagattctag cctctgttaa ggatgcatac acagcccgtt tggatgactg
    12241 gaatggcatc atcgctggga atcaatacta tgattctaaa aatgaacaga tggccaaatt
    12301 aaaccaggaa ttggaaggaa aggtagctga tagcctatct agtatttcaa gtcaggcgga
    12361 ccgcacctat ttgtgggaaa aattttcaaa ttataaaatg tctgcaaatc tgactgccac
    12421 ttatcggaaa ttggaggaga tggccaagca agtgaccaat ccttcttctc gttattatca
    12481 agatgaaact gtcgttcgaa cagtcaggga ttccatggaa tggctgcata aatatgtcta
    12541 caatagtgaa aagagcattg ttgggaactg gtgggattat gaaatcggta cacctcgtgc
    12601 catcaacaat accttgtctc tgatgaaaga atacttctct gatgaggaaa ttaaaaaata
    12661 tacagatgtg attgaaaaat ttgtaccaga tcccgaacat ttccgaaaga cgactgataa
    12721 cccattcaag gctctaggtg gaaacttagt tgatatggga agggtaaaag taatagctgg
    12781 tttactgcgt aaggatgatc aagaaatttc ttctaccatt cgctcgattg agcaagtgtt
    12841 caagttggta gagcaaggtg aaggttttta tcaagatgga tcctatatcg accacaccaa
    12901 tgttgcctat acgggtgctt atgggaatgt tttgattgat ggcctgtctc aactgttgcc
    12961 agtcattcaa aagaccaaga gtccaatcga taaagataaa atgcaaacca tgtaccactg
    13021 gattgataaa tcgtttgctc ctttgctggt gaatggagag ttgatggata tgagtcgtgg
    13081 acgctcgatc agtcgtgcaa atagcgaggg gcacgtggcc gcagtagaag tactaagagg
    13141 gattcaccga atagcggata tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt
    13201 gaagaccatt gttcaatcgg atagttatta tgatgtcttt aagaatttga agacttataa
    13261 ggatatcagt ttgatgcaat ccttgttaag tgatgcagga gtcgcaagtg ttccaagaac
    13321 aagttaccta tctgccttta acaagatgga taaaacagcc atgtacaacg cagagaaagg
    13381 gtttggattt ggcttgtcac tcttttccag tcgtaccttg aattacgaac acatgaacaa
    13441 ggaaaataaa catggttggt atacgagtga tgggatgttc tatctttaca atggcgattt
    13501 gagtcactat agcgatggct actggccaac agttaatcca tataagatgc ctggtacaac
    13561 agagacggat gctaagagag cggatagcga tacaggtaaa gttttaccgt ctgctttcgt
    13621 tggaacgagc aaactagatg atgccaatgc gacagcaacc atggatttca ccaactggaa
    13681 tcaaacattg actgctcata agagctggtt tatgctaaag gataagatcg cctttttagg
    13741 aagcaatatc caaaacactt caacagatac tgctgcaact acaattgacc agagaaaact
    13801 ggaatcaagt aatccatata aagtctatgt caatgataaa gaagcctccc ttacagaaca
    13861 agaaaaggat tatcctgaaa cccaaagtgt ctttttagaa tcgtccgatt cgaaaaagaa
    13921 tattggttac tttttcttta agaagagttc aatcagtatg agtaaggctt tgcaaaaggg
    13981 agcctggaag gatatcaatg aaggacagtc agacaaggaa gttgaaaatg aatttcttac
    14041 gattagtcag gctcataagc aaaatggaga ttcttatggc tatatgctta tccctaacgt
    14101 ggatcgtgcc accttcaatc aaatgataaa agagttagaa agtagcctca tcgaaaataa
    14161 cgaaaccctt cagtctgttt atgatgctaa acaaggagtt tggggcattg tgaaatatga
    14221 tgattctgtc tctactattt ccaaccaatt ccaagttttg aaacgtggag tctatactat
    14281 tcgaaaagag ggggatgaat ataagattgc ctactataat cctgaaaccc aggaatcagc
    14341 tccagatcag gaagtcttta aaaagctaga gcaagcagct cagccacaag tacagaattc
    14401 aaaagaaaag gaaaaatctg aagaggaaaa gaaccattcg gatcaaaaga atctccctca
    14461 gacaggagaa ggtcagtcaa tcttggcaag tctagggttc ttgctacttg gggcgtttta
    14521 tctattccgt agaggaaaga acaactaatt tgttcatcat ctagatgaat tacatgaaac
    14581 tgtggaaaat agaaaaaatc cgaagaaggc caaatatctt cggatttttc ttttaaaaaa
    14641 gataagttga tacttatcct tttttacttc attatgtgac tatagcgttt tgaaactaga
    14701 ataggacgtc ataactgcta aaagatttct ataaattcat ttgattttcc taatcaattt
    14761 gttcgtatcc tatttcactc cactatatta gtccgtctcg ctccgtgagg tgcgagacaa
    14821 aacaaccacc cgctatacgg gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga
    14881 tacaataaag gtgttcaatc caattgtaaa gcgaaaggag aaaaaatatg gcacaaaaga
    14941 ctcatagttt atcatacaca aagtggatgt gttctatcat attgtgttca cccctaagta
    15001 tagacgaaaa gtcatctata atcaatatag aagtagttta ggcgaaatat ttcatcgctt
    15061 gtgtagttat aaaggtgttg aaattatcga gggtcactta atgccagacc atgtacacat
    15121 gttagtcagt attccactaa ggctaagtgt ttcaagtttt atggggtatt taaaaggcaa
    15181 aagtgcactc atgatgtttg acaaacacgc caatctcaag tacaagtttg ggaatcggca
    15241 tttctgggcg gaaggttatt atgtaagtac agtagggctt aataaagcca cacttaagaa
    15301 atatagtcaa gattaaagaa attatccagt ggatgatttc ttcacgagta tgaaaatttg
    15361 agaactagta aagtatgata tatagtaaaa tgaaataaga acaggacaaa atcgatcagg
    15421 acagtcaaat cgatttttaa caatgtttta gaagtagagg tgtactattc cagtttcaat
    15481 ctactatagc actagataaa ttgagtgtaa aagaatatga ggatcccttt agggatagtg
    15541 gtaagtaata ccaaagtctc ttaaagaggc aagtgacgag tcaagagcaa taaggcttga
    15601 acaacgtgaa agccagcgtc tttaggcgct ggctgatgat ttgggcttat agctctgaga
    15661 taaaccaccc gttagacggg tagttatgat tttatctgag tgtaacatac tgttgggcaa
    15721 tctcgctgat gcggtcaaag ttgccttggg aagcgagttt attgagttcg ccaccaattc
    15781 caacggcatc tgcaccagca gcgaaccatt gagggatgtt gtttaggccg actcctccgg
    15841 ttaccattac ggaaacttgt gggatcggtg ccttgactgc agagatatat gctggactga
    15901 gagtactacc tgggaagagt ttgatgattt cactaccggc ttcaagtgca gtcgtgatct
    15961 ctgtgagggt aatacagcct ggaatgtacg gtgtgctgta gagattgcac attttcgcag
    16021 tttcagcatg gaaagatgga gaaacaacgt aatttgctcc agctagaatg gcatctctag
    16081 cagttacggc atcaagcaca gtacctgcac cgatacaaac actctgatcg tcctgataca
    16141 agtctacaag ttccttgatg atttgtcctg catactgatt ggtataggcg atttcaatag
    16201 ctttgatacc gcccttgata caagcaatcg aggcttgtag tccttcttcc tttgtatttc
    16261 ctcgaatgac agcgacaatt ttctgttttt ttagttcaat aatcgtatct gatttggtca
    16321 tgtaattctc ctaacgaatg atatcttgtg catttgccag taaattttca atactagttg
    16381 cggaagtgga gagatggtct cctggaagag tgcatttgag agttgcgctc gcaactgcaa
    16441 agtcaatggt agtttttagg gaggaatgat ggagtagttg gtaaagggca ccagatataa
    16501 aggcatcccc gctaccaatt cgttgataga ctgcagtttt tagttggaca gactcttcaa
    16561 atcgttcttc cagagcatag gcttgataga catttttgtc ttgctcatca ctagatcgga
    16621 gggtatggaa aatggccttg aaaccatagg cttcttttaa aagtcgcatg cgattttcca
    16681 cctcttctag gctagcactg tctcttggaa acatctctag attttggtca tcaatcatga
    16741 gaggatcaat accgaagcaa tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg
    16801 cttctaggac tgaaatcatc tttgttctca gattgagatc cattgaaacg acaattcctc
    16861 ggcgcttggc ttcttccaag agtaggagaa ggatcgcacg gacctcttga ccgatagcta
    16921 tggtgattcc actaaaatga aaatggctaa tcccctgaaa gagagaatcc atatctagca
    16981 tgtttggccg aatctggctg atactcgtat gcttacgatc gtagaaaact tcactttgac
    17041 gacaaccaaa gccgttctcc aaatagtaga ggccgattcg atcgccaagc cgacagattg
    17101 aactggtatc gatttggtgc tgtttcaaga atgtgagaaa acgatctcca atctcgttgg
    17161 cagggagtgc ggtaaagact ttcgttgaga tacccagggc ttgcaaatta caagcgatgt
    17221 taatttctga tccgccaaaa taagtcgaac tggcaacatg atcgccgata ctggtggcat
    17281 ctaatggtga gattcgaatt aatggttcgc caaacagtaa tattttcgtc atccattagt
    17341 tcctttctgg tttagaatag ctttacttgg ctaatacttc tttcaaataa gcagcgactt
    17401 catcatcttg gcagttttca aagaagtatt cttggaagta tttgccagag atggtgtctt
    17461 tgaggaagtc ttggtcgatt gttttaagga tggtcatcaa atcattgtgg gtgatttgtt
    17521 tcacctcgtt taagatacga gcgttgcgtt gttcagggat tacacgttct cttgggtagc
    17581 caccgcccat ttcttcagca aataagcgtt caaacatcaa tttgagggtc agttctgccc
    17641 cccagccaaa tcctttggca taagggatag acaaggcgtt accaccattg atttgagaat
    17701 aaaggtaagc gtcagttggg tccactgcta gaccacagac aacaccaggg aagctgttta
    17761 aagcaagcat agcccctaca cccgtaccac agccggtaac aacaaagtca actgcctttg
    17821 tatttaaaag gatggcagcc attagtccgt tctgcacata agttaattga ctttctcctt
    17881 cttctccacg cataccatag ttaaataatt ggtagtcttt tttatctgtc gcttctttta
    17941 gactatcgta aataatgtga ttcttgctag cttgactatt ttcattgatt aatgcgattt
    18001 tcataagatc ttctttctat ttttactcag gttgttttcc gatgtaggct aagataccgc
    18061 catctacata taggatgtgg ccattgacaa aattgctggc atcactagcg agaaagacag
    18121 cagggcccat caaatcttca ggatttcccc aacgtgcagc aggtgttttt gcaatgatga
    18181 actggtcaaa tgggtggcga gaaccatctt cttgcaactc acgaagaggt gctgtttgag
    18241 gagtggcaat ataacccggt ccaattccgt tacattggat attggctcca ccgtattcag
    18301 acgcaatgtt gcgggtcaac attttcaagc cccctttagc agcagcataa gcgctaactg
    18361 tttcacgtcc cagttcgctc atcatcgaac aaatattgat aatctttcca tgccctttct
    18421 ttatcataga aggaataact gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga
    18481 tgaccttacg gaaatcagcg gcgctcattt cgcacattgg aactcggcgg ataataccag
    18541 cgttattaac gaggatgtca atgacaccaa cctcttgttc gatttgcttg accatggctt
    18601 ggataccgtc ctcgtctgtc acgtcacaga catatccatg ggcttcgatg ccaacttcac
    18661 gataagcttc aatcccttta ttgaccagat cttgattgat atcgttaaag acaatagtag
    18721 cgccggcttc agcgtaggat ttggcaatag caaatccaat tccataagaa gcgccggtga
    18781 tgagagcaat ttttcctttt aaagaaaact gctcaattga gaatgatgta tttgtcattt
    18841 gatacttcct ttcaaatttg ttaagacttc tctataatca aattatattc tagtaa
//
LOCUS       DBEJNA010000041        17140 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEJNA010000041 DBEJNA010000000
VERSION     DBEJNA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.41"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..370
                     /locus_tag="ACL3JB_001728"
     CDS             <1..370
                     /locus_tag="ACL3JB_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0686419.1"
                     /translation="GAMATGWAKVNGSWYYLNANGSMATGWLQYNGSWYYLNANGAMA
                     TGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLG
                     ALAVNTTVDGYKVNANGEWV"
     gene            771..1892
                     /gene="mnmA"
                     /locus_tag="ACL3JB_001729"
     CDS             771..1892
                     /gene="mnmA"
                     /locus_tag="ACL3JB_001729"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0686420.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2033..2488
                     /locus_tag="ACL3JB_001730"
     CDS             2033..2488
                     /locus_tag="ACL3JB_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0686421.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAAVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2498..4411
                     /gene="mnmG"
                     /locus_tag="ACL3JB_001731"
     CDS             2498..4411
                     /gene="mnmG"
                     /locus_tag="ACL3JB_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0686422.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4790..6469)
                     /locus_tag="ACL3JB_001732"
     CDS             complement(4790..6469)
                     /locus_tag="ACL3JB_001732"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0686423.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6471..6704)
                     /locus_tag="ACL3JB_001733"
     CDS             complement(6471..6704)
                     /locus_tag="ACL3JB_001733"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0686424.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6984..7199
                     /locus_tag="ACL3JB_001734"
                     /pseudo
     CDS             6984..7199
                     /locus_tag="ACL3JB_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7522..7674)
                     /gene="cibB"
                     /locus_tag="ACL3JB_001735"
     CDS             complement(7522..7674)
                     /gene="cibB"
                     /locus_tag="ACL3JB_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0686425.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7676..7861)
                     /gene="cibA"
                     /locus_tag="ACL3JB_001736"
     CDS             complement(7676..7861)
                     /gene="cibA"
                     /locus_tag="ACL3JB_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0686426.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8039..8722
                     /gene="tsaB"
                     /locus_tag="ACL3JB_001737"
     CDS             8039..8722
                     /gene="tsaB"
                     /locus_tag="ACL3JB_001737"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0686427.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8719..9156
                     /gene="rimI"
                     /locus_tag="ACL3JB_001738"
     CDS             8719..9156
                     /gene="rimI"
                     /locus_tag="ACL3JB_001738"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0686428.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            9146..10156
                     /gene="tsaD"
                     /locus_tag="ACL3JB_001739"
     CDS             9146..10156
                     /gene="tsaD"
                     /locus_tag="ACL3JB_001739"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0686429.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10196..11502)
                     /locus_tag="ACL3JB_001740"
                     /pseudo
     CDS             complement(10196..11502)
                     /locus_tag="ACL3JB_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11838..12529)
                     /locus_tag="ACL3JB_001741"
                     /pseudo
     CDS             complement(11838..12529)
                     /locus_tag="ACL3JB_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12772..13326
                     /locus_tag="ACL3JB_001742"
     CDS             12772..13326
                     /locus_tag="ACL3JB_001742"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0686430.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIRLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            13454..13915
                     /locus_tag="ACL3JB_001743"
     CDS             13454..13915
                     /locus_tag="ACL3JB_001743"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0686431.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHESI"
     gene            13939..14814
                     /locus_tag="ACL3JB_001744"
     CDS             13939..14814
                     /locus_tag="ACL3JB_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0686432.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
     gene            14901..16517
                     /locus_tag="ACL3JB_001745"
     CDS             14901..16517
                     /locus_tag="ACL3JB_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0686433.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16865..>17140
                     /locus_tag="ACL3JB_001746"
     CDS             16865..>17140
                     /locus_tag="ACL3JB_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686434.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKGLIFFNKIVNGLIQN"
BASE COUNT         5218 a         3001 c         3805 g         5116 t
ORIGIN      
        1 cggcgctatg gcaacaggtt gggctaaagt caacggttca tggtactacc tcaacgctaa
       61 cggttcaatg gcaacaggtt ggctccaata caacggttca tggtactacc tcaacgctaa
      121 cggtgctatg gcaacaggtt gggctaaagt caacggttca tggtactacc taaacgctaa
      181 cggttcaatg gcaacaggtt gggtgaaaga tggagatacc tggtactatc ttgaagcatc
      241 aggtgctatg aaagcaagcc aatggttcaa agtatcagat aaatggtact atgtcaatgg
      301 cttaggtgcc cttgcagtca acacaactgt agatggctat aaagtcaatg ccaatggtga
      361 atgggtttaa gccgattaaa ttaaatcatg ttaagaacat ttgacatttt aattttgaaa
      421 caaagataag gttcgattga atagatttat gttcgtattc tttaggtacc tatcttatga
      481 tttcaggaaa tgtcattaaa aaaacgactc cttttctcta acttgaaaaa tagattagag
      541 aaaatgggtt gttttattta ttatagttat ttgaatgaag ataagaataa ggtatactca
      601 catcatttac ataatctgta tattgactat aagttttaaa aaacaatttt taagctcttc
      661 cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct tcaatcgtga
      721 agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc atgagtgata
      781 actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg gtgacggctc
      841 ttttgctcaa ggagcagggc tacgatgtga tcggtatctt catgaagaac tgggatgaca
      901 cagatgaaaa cggcgtctgt acggcgaccg aagattacaa ggatgtggtt gcggtggcag
      961 accagattgg cattccctac tactctgtca attttgaaaa agagtactgg gaccgcgttt
     1021 ttgagtattt cctagcggaa taccgtgcag ggcgcacgcc aaatccggac gttatgtgca
     1081 acaaggaaat caagttcaag gcctttttgg actatgccat aaccttgggg gcagactatg
     1141 tagcgactgg gcattatgct cgagtggcgc gtgatgagga tggtaccgtt cacatgcttc
     1201 gtggcgtgga caatggcaag gatcagacct atttcctcag ccaactttcg caagaacaac
     1261 ttcaaaaaac catgttccca ctaggacatt tggaaaagcc tgaagttcga aaactagcag
     1321 aagaagcagg tctttcgact gctaagaaga aagactcgac agggatttgc tttatcggag
     1381 aaaagaactt taaaaacttt ctcagcaact acctgccagc tcagcctggt cgcatgatga
     1441 ctgtggatgg tcgcgatatg ggcgagcatg caggtctgat gtactatacg attggtcagc
     1501 gtggcgggct tggtatcggt gggcaacacg gtggtgacaa tgccccttgg ttcgttgtcg
     1561 gaaaagctct aagcaagaat attctctatg taggacaagg attctaccat gattcgctca
     1621 tgtcaaccag cctagaggct agccaagtcc actttacttg tgatatgccc gaggagttta
     1681 cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg accgtccatg
     1741 tcaaaggaga caaggcagag gtcatctttg cggaaccaca acgcgccatt acaccaggac
     1801 aggcagttgt cttttacgat ggcgaagagt gtctaggtgg cggtttgatt gacaatgctt
     1861 accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa tttgctacaa
     1921 taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt ttttgtcctg
     1981 cacttctttg tagttttgac tgtttttgtg tcgtttaagg gaaaggacaa gaatgactca
     2041 acaagacttt cggacaaaag tagacaatac ggtttttggt gttcgggcga cagccttgat
     2101 tgtccaaaat cacaagcttc tagttaccaa agacaagggc aagtattaca ctattggagg
     2161 tgcgattcaa gtcaatgaaa gcacggaaga cgcggcagtc cgtgaagtga aggaagaact
     2221 gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt ttgaagtgga
     2281 cggcgtttcc tatcacaata tcgagtttca ttatctggtg gatttgcttg aagatgcccc
     2341 gttgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact tggataagct
     2401 tgaggatatc cagctagttc cagccttttt aaaaacggcc ctaccagatt gggaaggcca
     2461 actaagacac attcatcttg aggaatagga gagaaacatg acttatcatt ttactgaaga
     2521 atacgatatt attgtaattg gtgcgggaca cgctggggtt gaggcttcct tggccgctag
     2581 ccgtatgggc tgtaaggtcc tgcttgcgac catcaatatt gaaatgctgg ctttcatgcc
     2641 ttgtaatccc tctatcggtg gttctgccaa ggggattgtc gtgcgtgaag tcgatgccct
     2701 cggtggcgag atggccaaaa ccattgacaa gacttacatc cagatgaaga tgctaaacac
     2761 agggaagggg ccagctgtcc gtgcccttcg tgcgcaggct gacaaggaac tttactctaa
     2821 ggagatgcgc aagacggttg aaaaccaaga aaatctgacc cttcgtcaaa ccatgattga
     2881 tgagattttg gtggaagatg gcaaggttgt cggtgtgcgt acagccaccc atcaagaata
     2941 tgctgctaag gctgttattg tgacgacagg gactgctctc cgtggggaaa ttatcatcgg
     3001 agacctcaag tactcatcag gtcctaacca cagcttggct tctattaacc tagctgataa
     3061 tctcaaggaa ttaggactcg aaatcggtcg tttcaagaca ggaacccctc cacgtgtcaa
     3121 ggcttcttct atcaactacg acgtgacaga aattcagcca ggagacgaag tgcctaatca
     3181 tttctcatac acttcacgtg atgaggatta tgtcaaagat caagtgccat gctggttgac
     3241 ctacaccaat ggtaccagtc atgagattat ccaaaacaac ctccaccgtg cgcctatgtt
     3301 tacaggtgtg gtcaagggag tggggcctcg ttactgtccg tcgattgaag acaagattgt
     3361 gcgctttgcg gacaaggaac gtcaccaact cttccttgag ccagaagggc gcaatactga
     3421 ggaagtctat gttcaaggac tttcaaccag tctgcctgag gatgtccagc gtgacttggt
     3481 tcattccatc aaaggtttgg aaaatgcaga gatgatgcgg acaggttatg ctattgagta
     3541 tgatatggtc ttgcctcatc agttgcgtgc gactctggaa accaagaaaa tctcaggtct
     3601 cttcactgct ggtcagacaa atggaacgtc aggttacgaa gaggcagcag gccaagggat
     3661 tatcgcgggt atcaatgcgg ctctgaaaat ccaaggtaag cctgagttga ttttgaagcg
     3721 aagtgacggt tatatcgggg tcatgatcga cgacttggtg accaagggaa ccattgaacc
     3781 ttaccgtctc ttgaccagtc gtgctgaata tcgtctcatt cttcgccatg acaatgctga
     3841 tatgcgcttg actgagatgg gacgcgagat tggccttgtg gatgatgaac gctgggctcg
     3901 ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa cgcctagaca gtatcaaact
     3961 caagccagtc aaggaaacca atgctaaggt tgaggaaatg ggcttcaagc cgttgacaga
     4021 tgcggtgaca gccaaggaat tccttcgccg tccagaagtt tcttaccaag atgtggtggc
     4081 cttcatcgga ccagctgcag aagacttgga tgacaagatt atcgaattga ttgaaacaga
     4141 aatcaagtat gaaggctata tttccaaagc catggaccag gttgccaaga tgaaacgcat
     4201 ggaagaaaaa cgcattccgg ccaatatcga ctgggatgac attgattcta tcgcaaccga
     4261 agcccgtcag aagttcaaac tcatcaatcc agaaaccatc ggccaagcca gccgtatttc
     4321 gggagtaaac ccagcagata tttctatttt gatggtgtat ctggaaggta aaaatcgtag
     4381 tatttctaaa actcttcaaa aatcaaaatg atacgtcgta ggcttcttac gaatgagttc
     4441 aaagcttggc tttgattcat ctccaacctc ccatagttcc ccgaactatg ggagctaact
     4501 caagttatgc attttcctag ccttctggtc tgattttcat tgagttttaa tctaaaaaga
     4561 aagcatagag aaaaacagct ccgaagacgg ggctgttttg ttgatttgta ctcaatgaaa
     4621 atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt tgaggttgta
     4681 gatagaactg acgaagtcag ctcaaaacac cgttttgagg ttgtggatag aactgacgaa
     4741 gtcagtaaca tatatacggc aaggcgaagc tgacgtggtt tgaagagtat tattcttcat
     4801 ctggtgtgag gatcatcggg atgatgatcg gttcacgttc ggtattttca tagaggaagg
     4861 ggcgaatagc gttgacaatg gcaccattga cagattgcac gctagcatcc ttatttttca
     4921 gtgcgatacg aatggcattg aagaggatac gctggctttg gcgaatcaag tcgccagact
     4981 ctctcatgta gacaaagcct cggctgagga tgtctggacc agatagaatc atctgcgatt
     5041 tgaagtcaac agttgcgact gccagaacga caccgtcttc agatagatcg cgacgatctt
     5101 tgaggacagc tgcgccaatt tcaccgatac gatttccatc gacatagata tcttgggcgt
     5161 tgaaatggcc tgcgatacga gctgagtcag cagtaagggc aagcacatcg ccattgctca
     5221 tgataaagat attgtccttc tcaacaccag tatccactgc tagtccagcg tggacttttt
     5281 gcatgcggta ttcaccgtgg acaggcatga agtattttgg cttaatcaag cagagcatga
     5341 gtttttgctc ttgctgacca ccgtgtccag atgtatggat attgttcact ttaccgtgga
     5401 taacttcgac accagcttca gaaatgatgt taatcagctt gttgacgcta gtagtgtttc
     5461 cagggatggg actagaagag aagataacgg tatcacctgg ttgtaattgt acttgacggt
     5521 gggttccgtt ggcgatacga gagagggctg ccataggctc accctgacta cctgtacaga
     5581 ggataagaac ttctcctgca ggataatctt tgatttcatt tggctcgata aaggttccct
     5641 taggagcttt gatgtagcca agatcgattc cgttgacaat ggccttttcc atagaacgac
     5701 caaagaccgc aatcttgcgt ccagtcttaa cagcagcttc tgttgcctgc tggagacgga
     5761 agatatttga ggcaaaggat gcaaagatga tacgtccttc aataccttgg ataatcttca
     5821 taatggactg accaacgact ttttcagagt tggtaaaggt tggtacttcc gcatttgtcg
     5881 agtcagacag gagacagagc acgccttctt caccaagcgc agccatacga tgcaagtccg
     5941 caggttctcc aactggagta aagtcgaact taaagtcacc cgtacagacg attttccctt
     6001 gaggagtatg aatgacaatc cccaaaggct ctggaataga gtgagtcgtt ctaaagaaag
     6061 ttgccttgag atttttaaag gtcaactcgg tgttgtggtt gatttcgtaa agtttggcgt
     6121 tgcgcaagag gccgtgttct tcgagtttcc cacggatcaa agccaaggca agcggtccag
     6181 cataaatagg gacatttgct tgcttgagta ggaacggaat cccaccaatg tggtcctcgt
     6241 gtccgtgtgt gattaaaaca gccttgacgc ggtcgatatt gtctacgatg taagagtagt
     6301 caggaatgac atagtcgata ccaagcaagt catcttctgg gaatttaatc ccagcatcga
     6361 cgatgataat ctcgtcttgg tattcaattc cgtaagtgtt tttcccgatt tctcctagac
     6421 caccgatggc aaaaacgccg acttcttcag gtttaagagt gtaggccata ttagaactcc
     6481 gtaatttcga aggcgccagt ttctttttcg taatcgagca atttgtcaga caagagttcg
     6541 atatattcga tattgtactc tgggcgattt tcttcgacaa gttggcgagc agtgatacgg
     6601 ccctcaagtt ctgagctggc atcgatgtct aggtaaagcg cgcgtgttgt ttcacggcgt
     6661 gggctacgtt cttttgtttc ttgataaaaa actttgtaaa tcatatagtt cctttctatt
     6721 tacaggtcag cttattccaa acttttagca gatatttgct tgatttcatt ccattttgtg
     6781 tctagattga ccttgattcg ttacaattat ttcaattata ccacaaaatg aaaaattagt
     6841 aaaagacgga aacgagaaag ttagggggca atttctttgg taagcgttta caaaaataaa
     6901 gaaaatgtat tatgttgata acggaagtga aatttattgc ttgtcataat tccatataga
     6961 ttttaagtca aggaggttgc cctatgtata acttatttgc ttttgctatc ggagttcgtt
     7021 tgttagcttt tatcgttttt gttgcttgcg tttatggagg aaatcttcca tttgccaaac
     7081 tggaacgatg acaaaccaag ttcttgtgga aaattacctt tgtgactctc tactcgcttt
     7141 ttctcctcct cgtgccctat gtcgtttggt ttgtatttta ctttggatta aatgcttaga
     7201 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     7261 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     7321 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     7381 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     7441 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     7501 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     7561 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     7621 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     7681 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     7741 tagccttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     7801 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     7861 ttgaactttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     7921 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     7981 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     8041 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctggctattt tagaggataa
     8101 gcaggttctt gccgagacga cgattaatat taagaaaaat cacagtatta ctcttatgcc
     8161 tgccatcgat tttttgatgg caagtttgga ttggacaccc aaggatttgg accgaatcgt
     8221 ggtagctgaa gggccgggta gctatacagg cttgcgaatt gcggtagcaa ctgctaagac
     8281 cttagcttac accctgaaca tcgagttggt tggtatgtcg agtctcttgg ctctggtgcc
     8341 ccaccaacaa gaaggtttgt ttgtcccctt gatggatgcg cgtcgcaata atgtttatgc
     8401 aggattttat gaaaatgcta aacctgtcat ggcagaagcg cacctatctt ttgaagaggt
     8461 gctagaaaaa gtcaagggta ctagtcaggt aacctttgtc ggagaagttg gcccctttgt
     8521 tgagcagatt caaaaacact tgccaaggac tgattacaaa gaaacattgc ccaatgcagc
     8581 taatctagct cttttggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     8641 ttacctcaaa cgagtcgagg ctgaggaaaa ctggctcaag aaccataccg agtctggtga
     8701 gtcctacatt aaacgcctat gatagaaatc aaacgaatcc aacagcagcc tgatctagct
     8761 aaagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     8821 atccaagctg acctgttcca agaccagact tggtatgctc tggcttatga tggggcagaa
     8881 gtgattggct ttctagctgt tcaggagact ctctttgaag cagaagtcct gcaaatcgct
     8941 gtcaaaggag cctatcaggg taagggcatt gcgtcagcct tgtttgctca attgccgaca
     9001 gataaggaga ttttcctcga agtcagaaag tcaaatcaac gagcgcaagc attttacaag
     9061 aaagaaaaaa tggcggtcat cgctgatcga aaggcctact accatgaccc agtcgaggac
     9121 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     9181 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     9241 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     9301 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     9361 cgaagaggat gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     9421 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     9481 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     9541 gctagccctc ttggttagcg gtgggcacac agagttggtc tatgtttcgg aggcaggaga
     9601 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     9661 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgagctgg ctcatcaggg
     9721 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     9781 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     9841 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     9901 aaaaaccaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     9961 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
    10021 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
    10081 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
    10141 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
    10201 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
    10261 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
    10321 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
    10381 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
    10441 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
    10501 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
    10561 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
    10621 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
    10681 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
    10741 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
    10801 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
    10861 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
    10921 gaaatggttt cgaatcaccg catgagttcg cccgtctaaa attgcgagga tggatttgga
    10981 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
    11041 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
    11101 gacggtggaa gttgagaccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
    11161 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
    11221 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
    11281 atgtagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
    11341 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
    11401 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
    11461 tttcaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
    11521 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
    11581 tataattcct ggggtgggat tacccactac agaaattata gagccaaaac attccaaagt
    11641 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
    11701 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
    11761 aaaactggag gattttttta tgtcccccca tcgtcccatc gactgttccg tagctgccca
    11821 ataacggagt atagtcggct gaaacaagaa taggacaaaa gtgcctcaag aaaagcatcg
    11881 taatttgaca atattattct gagatgtttt tgatgtaagc ccatattttc tcaatgggat
    11941 tatactcggg tgaataggta ggaagtggta acagtctatg ccctgctcct tacacatgtt
    12001 cattctgtga aaccttgcat tgtccataat gataagggat ggtgtatcta aagtaggtag
    12061 taagaatttt tggaagcaag cttcgaaaaa gtcactcgtc atcgtatctt tataggtcat
    12121 cggagccata gtatattgaa acaaaaaagg gcattagtac ttctataaca gtatcgcaat
    12181 ctctggtgtg cgttgtctcg atcttaattc aaataattat atcttcttcc agagagacta
    12241 actgcctgct caaggctcga tcatattcga gataaaaata ggtctcaacc cctgtctcat
    12301 aaatataaat aggagtcagg tagcttaagt gattcaattc tttaaggaac cgatttactt
    12361 tttctgggtc ttgttcgcag taggtacagc tcttttttag actatatccc atagccttta
    12421 gagcgtaatg aatagttgtt ggaggacagt tgaattcagc agctatttca gtcaaataag
    12481 catcgggatg agtttcaata tagatcttta atttatctct atcaactttt tcaattaata
    12541 gtggaagttt tcttaaagtt agtgtgttga aacgttttta tacagtgcta aaatttgaag
    12601 tgtagtgcag atgtatttgt aatagtatta tagcaattct ttggagaagg tcgagacaag
    12661 agaaaatagg tatctttgag atataagcat gatttactat aaaattattg agttattcat
    12721 aaaaatttct ctatcaaata tcataatgcg tcgtttaagg agatggttac aatgcaatat
    12781 agttgtggaa aaataaatat taatatccct gatggatatg gagacattaa ggatatagtg
    12841 ttttcggctc atattatagt taggtataat aatggacatt gtggaggtat agatccgcat
    12901 ataattggac tttgtaaaaa gcagatcaga aggatgtctc tatatcctat tttgataatc
    12961 gtatctagag attcaaaggt tattgatgat tataaaaatt tagatattgc ctatgttgat
    13021 tgtactcaat gttcaaataa ttttgaaact gccttacacg ttaaaaatat tttaaaatta
    13081 ttaaaaatcc gacttataca ctgtcatggc tactcaacta attatttttt atatatgtta
    13141 aaaaaacttg acaagaatgg atttggaaag gttaagacag tgataacatg ccatggatgg
    13201 gttgaatata acttaaaaaa gaaattcttg acttattttg atttttggac atattctatg
    13261 ggagatgctt ttatttgtgt atctgaaact atgaaaaaaa gattggagag tataataaaa
    13321 aaataagaag atagttgcaa taaataacgg aattaatgta tcaaatagcg atttagatgt
    13381 agtaggtgtt caagacttta aaaaagaatt ttgtattcca aataacaaaa aaatcatttg
    13441 ttatgttgaa aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
    13501 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
    13561 tgctttgaaa gaaaaaattt gccatttgaa atgtagagat aatttcaggt tacttggtga
    13621 aatctatcca gctactatag tttaccaaat atcggattta ttgtatattc cttctgatac
    13681 agaaggaata cctatgtgtg ttttagagtc aatgtcacaa ggaactccgg ttttagctag
    13741 taatgttggc gggttaagtg aaattattga acatagggtt gatggatttt tatttgagaa
    13801 ggaagatgtt gagggagtgt gtgcttgtgc taatttttta ctcaatgatt ctgagtattt
    13861 gaaatatata ggtgagaata gtaaatcaaa aataagaaaa catgagagta tatgatgaat
    13921 tattagagaa gagtagtcat ggataggaat atagatcaag aattagtaag tattataata
    13981 ccaacacata ataggtatga atctctgatt agagctgtga aaagttgttt acatcaaagt
    14041 tataaaaata tcgaagttat aattattgat gataattata gtaatgtaaa tttaagaaat
    14101 aaaattatcc atcaatttgg ctataccaat catagaatta agttaatttt aagtaatgaa
    14161 gatttaggtg caactaatgc cagaaacata ggtatcaaaa attctagagg taagtatata
    14221 tcatttttag acgatgatga tgaatatatg ccagatcgaa ttttaaagtt gatggcttgt
    14281 tttaaaaaga gtagaatgaa gaatttagct ttagtttata gttatggaat aataatttat
    14341 ccaaatggta cacgagaaga ggagaagacc gattttgttg gaaatccctt gtttgttcaa
    14401 atggttcaca atatagcagg tacgtcattt tggttgtgta aaaaagaggt gctagaatta
    14461 attaatggtt ttgagaaaat agattcacat caggacggtg ttgttttatt aaaactactt
    14521 gctcaaggat accaaattga tatagtgcga gaattcttgg tgaattacta cgctcacagt
    14581 aaagaaaacg gtatcactgg agtgacacaa aaaacaatta atgcagatga agaatattat
    14641 aattactgta ggaaatattt taatttattg agtttcaacg agagaatatt ggttacaaag
    14701 aaatattatt ctttaaacat aaagcggtta ctattaatag gagacaaatg caaggcttta
    14761 aaagtaatca agaaggcaag agaagaaaaa atttttaacg aatttctttt ttgaaatata
    14821 tgttattata tcattttggt tttttctatt gtatatatga caactatgtt caattaaaat
    14881 ttagaaagtg agaaactatt gtgtatacta ttataaaatc aaatataaaa aaatttagtt
    14941 tattaacgat atttattgtt gctggtcaat tattgctaat ttatgcagca actattaatg
    15001 ctctggtgtt gaatgaatta attgcgatga atttagagcg gtttttgaaa ttgtcaatct
    15061 accaaatgat tgtctggtgt gggataatat tccttgactg ggtagtgaaa aattatcagg
    15121 ttgaagtgat ccaagagttt aatctagaga ttcgaaatag agttgccaca gacatctcta
    15181 actctaccta tcaagaattt catagtaaat catcaggaac atatctttcg tggctaaata
    15241 atgatgttca gactttaaat gatcaggctt ttaaacaact ttttttagta ataaaaggaa
    15301 tttctggtac tatatttgca gttgtgactc ttaatcacta tcattggtca ttgactgtag
    15361 ccaccttgtt ttcattaatg attatgctac ttgtaccaaa aatctttgca tcgaaaatgc
    15421 gagaagttag tctaaattta actagccaaa atgaagcttt tttaaaatct agtgagacta
    15481 tattgaatgg atttgatgtg ttagcgtcct tgaatctttt atatgtattg cctaagaaaa
    15541 ttaaagaagc aggaatttta ttaaagatgg ttatacaaag aaagacaact gtagaaacgt
    15601 tagcaggcgc tattagcttc tttctcaata ttttttttca gatatctctc gtttttttaa
    15661 caggctatct tgcaataaaa ggaatagtga aaattggtac tattgaagca ataggagcac
    15721 taacaggtgt tatttttaca gcgctaggtg aattaggagg tcaattatcc tctattattg
    15781 gtacgaagcc tattttttta aaattgtatt caattaatcc aattgagtca aataaaatga
    15841 atgatatcga accaaatgag gtgaatagag attttccgtt atatgaagca aaaaatattt
    15901 gctataagta tggagataaa gaaatattaa aaaacttaaa tttttgtttt caacgtaatg
    15961 aaaagtattt aattttaggt gaaagtggaa gcgggaaatc tacattatta aaattattga
    16021 atggcttttt gagagattat agtggagaat tgcgattctg tggggatgat ataaaaaaaa
    16081 cctcctattt aaatatggtt tcgaatgttc tatatgtaga tcaaaaagct tatttgtttg
    16141 aaggtacgat tagagataat attttattgg aagaaaatta tactgatgaa gaaatactac
    16201 agtctttaga acaagttggt ttgagtgtaa aagattttcc taataacatt ttagattatt
    16261 atgttggtga tgatgggaga ttactgtcag gagggcagaa acaaaaaatt actttagcta
    16321 gaggcctaat tagaaataag aaaatagtat taattgacga gggaacttct gctatcgata
    16381 ggagaacttc gttagcgatt gaacgtaaga tattagatag agaggatttg actgtcatta
    16441 ttgttaccca tgctccgcat ccggaactta aacaatattt tactaagata tatcaatttc
    16501 caaaggattt tatttaagaa tataggggag ggaaacatga gattctattg tgaagcttat
    16561 gaggtaatta ctgaagagaa aaaagtatac tttaatgata ttgagttaga agttaagtat
    16621 tcctctgtcg aagaattgtt tataatatgt gagaaattat tagataagaa aaaagtatca
    16681 ttttttatgt agatgagaaa cccttaaggt atctgttatt tgactatata tttctactag
    16741 ttctagctaa aaaaatatcc caatcttatg aactgcaccc caaaagttag atttattctg
    16801 tctaactttt ggggtgcagt tcattttgca tagttttggc attcatccta gatatccata
    16861 taaaatgtct gagattgttg aaatgtctaa aaaaatatca gatctaaacg ataaaaaaga
    16921 atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata acataaatag
    16981 tgtcccgggt acaactcatt tatttagttg tttaaatatt caaacattag taaaaattat
    17041 tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag ataaagggct
    17101 tatctttttt aataagattg taaatgggct gatacaaaat
//
LOCUS       DBEJNA010000042        16695 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEJNA010000042 DBEJNA010000000
VERSION     DBEJNA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.42"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            59..637
                     /locus_tag="ACL3JB_001747"
                     /pseudo
     CDS             59..637
                     /locus_tag="ACL3JB_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(736..2358)
                     /gene="groL"
                     /locus_tag="ACL3JB_001748"
     CDS             complement(736..2358)
                     /gene="groL"
                     /locus_tag="ACL3JB_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0686435.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2374..2658)
                     /gene="groES"
                     /locus_tag="ACL3JB_001749"
     CDS             complement(2374..2658)
                     /gene="groES"
                     /locus_tag="ACL3JB_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0686436.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2814..3209)
                     /locus_tag="ACL3JB_001750"
     CDS             complement(2814..3209)
                     /locus_tag="ACL3JB_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0686437.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3287..4048)
                     /locus_tag="ACL3JB_001751"
     CDS             complement(3287..4048)
                     /locus_tag="ACL3JB_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0686438.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTIVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4081..4707)
                     /gene="ytpR"
                     /locus_tag="ACL3JB_001752"
     CDS             complement(4081..4707)
                     /gene="ytpR"
                     /locus_tag="ACL3JB_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0686439.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNMERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4723..5040)
                     /locus_tag="ACL3JB_001753"
     CDS             complement(4723..5040)
                     /locus_tag="ACL3JB_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0686440.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5037..5336)
                     /locus_tag="ACL3JB_001754"
     CDS             complement(5037..5336)
                     /locus_tag="ACL3JB_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0686441.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATFYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5534..5731)
                     /locus_tag="ACL3JB_001755"
                     /pseudo
     CDS             complement(5534..5731)
                     /locus_tag="ACL3JB_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(5973..6647)
                     /locus_tag="ACL3JB_001756"
     CDS             complement(5973..6647)
                     /locus_tag="ACL3JB_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686442.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6653..7099)
                     /locus_tag="ACL3JB_001757"
     CDS             complement(6653..7099)
                     /locus_tag="ACL3JB_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0686443.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7213..7716)
                     /locus_tag="ACL3JB_001758"
     CDS             complement(7213..7716)
                     /locus_tag="ACL3JB_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0686444.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7713..8075)
                     /locus_tag="ACL3JB_001759"
     CDS             complement(7713..8075)
                     /locus_tag="ACL3JB_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR0686445.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8141..9172)
                     /locus_tag="ACL3JB_001760"
                     /pseudo
     CDS             complement(8141..9172)
                     /locus_tag="ACL3JB_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(9179..10000)
                     /locus_tag="ACL3JB_001761"
     CDS             complement(9179..10000)
                     /locus_tag="ACL3JB_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686446.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMLFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLDFPKQSLIQGLIDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(10016..10487)
                     /locus_tag="ACL3JB_001762"
                     /pseudo
     CDS             complement(10016..10487)
                     /locus_tag="ACL3JB_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(10611..11327)
                     /locus_tag="ACL3JB_001763"
     CDS             complement(10611..11327)
                     /locus_tag="ACL3JB_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0686447.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12208..13623)
                     /gene="ply"
                     /locus_tag="ACL3JB_001764"
     CDS             complement(12208..13623)
                     /gene="ply"
                     /locus_tag="ACL3JB_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0686448.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13634..14044)
                     /locus_tag="ACL3JB_001765"
     CDS             complement(13634..14044)
                     /locus_tag="ACL3JB_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686449.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(14037..14645)
                     /locus_tag="ACL3JB_001766"
     CDS             complement(14037..14645)
                     /locus_tag="ACL3JB_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686450.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14658..15116)
                     /locus_tag="ACL3JB_001767"
     CDS             complement(14658..15116)
                     /locus_tag="ACL3JB_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0686451.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15241..15640
                     /locus_tag="ACL3JB_001768"
                     /pseudo
     CDS             15241..15640
                     /locus_tag="ACL3JB_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16404..16664)
                     /locus_tag="ACL3JB_001769"
     CDS             complement(16404..16664)
                     /locus_tag="ACL3JB_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686452.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         4918 a         3813 c         3000 g         4964 t
ORIGIN      
        1 gctttcaaat ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc
       61 taaaatcgtt cttgatcgct ttcacattgt acaacatctt agccgtgcta tgagtcgtgt
      121 gcgtgttcaa attatgaacc aattggatcg aaaatcccat gaatacaagg ctatcaagcg
      181 ctactggaag ctcatacaac aggatagccg taaactgagt gataagcgat tttatcgtcc
      241 tacttttcgt atgcatttaa ccaataaaga gattttagac aagcttttga gctattcaca
      301 agacttgaaa catcactatc agctctatca actcttgctg tttcactttc agaataagga
      361 accggagaaa tttttcggac ttattgagga caatcttaag caagttcatc ctatttttca
      421 gactgtcttt aaaaccttcc tcaaagataa ggaaaagatt atcaacgccc ttcaactaca
      481 ctattctaac gccaaaccgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc
      541 ctttggtttt cgaaactttg aaaacttcaa aaaacggatt tttatcgctt tgaacatcaa
      601 aaaagaaagg acgaaatttg tcctttctcg agcttagctg acttcaaccc actacagttg
      661 acaaagagcc tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg
      721 ttttctatag aaagcttaca tcatcccgcc catcatgctt ggatccattg ctggagctgg
      781 ggctactggt tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac
      841 agatgctgca ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc
      901 aatcatgtta acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt
      961 caaacgatcg ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacagg
     1021 ttcttccaaa gcacggagaa caatattacg tcctgttact tcatctcctg tcaattccaa
     1081 ggtagcaaca gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc
     1141 ttcaacagct gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa
     1201 ctcagtttca gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa
     1261 gcgttcttgc aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat
     1321 aaccgcaaca cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct
     1381 atctttgtcc acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa
     1441 ctcaagacca aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag
     1501 catggctttg cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc
     1561 acgaatcttg ttcaaaacaa gagttggaag agcctcacca tccacatcat ccgcaataat
     1621 caagagtgga cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt
     1681 ggaaattttc ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc
     1741 gctatctgtc accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac
     1801 ttcaagctct gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac
     1861 tttttccatt gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc
     1921 aacttgagcg atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac
     1981 tgctgcggca actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt
     2041 gacgtttttg attccttcac ggacgatagc ttgggtcaag actgttgcag tcgtagttcc
     2101 gtcacctgcg atatcattgg ttttagaagc tacttctgat actaacttag cacccatatt
     2161 ttcaaaatgg tcttccaatt cgatttcttt ggcaatggtc acaccgtcat tggtaatcaa
     2221 gggtgaaccg aatgactttt caagaacgac attgcgacct tttggtccca aggttacttt
     2281 aacagtgtct gcaaggatat cgacaccacg aaccatggct gaacgggcat ctgatgaaaa
     2341 tttaatttct tttgacatac ttactttctc cttctattcc tcaatgattg ccaaaatgtt
     2401 agcttcgcct acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc
     2461 ttcaactaag acacgatctc cagttttaac acttggagca accaagtcac cgttcaaggt
     2521 acgaacacct tgtccagtag ccacaacttg agctgttttg gttttttctt gggctgagcc
     2581 tgcaaggaca aagcccccaa cggtttgttc tttttcttct atttttaaga gcacacggtc
     2641 ccctaatggt ttcaacatct gatttcctcc ataatgagat agatattatt agcactcttt
     2701 gaactggagt gctaattcat aattctattg tatcacttgg tcagaaatag tcaagaaaaa
     2761 agtctgactt tctcaagata aaaagcctga gaccaactca gactttttaa ttcttaaaat
     2821 ggcaattctt cctcttccaa gaccaaatct gccaaatctt ggcctgcatt attttcacgc
     2881 atagcacgtt gggcacgact ttccaagagt tggaatcctg tcacaaggac ttcggttaca
     2941 taattcatct gaccattttt ctcaaagcga cgggtacgca attctccatc aacggaaatg
     3001 agactacctt tggttgcgta gcttgccaaa gtttctgcta gtctgcccca tagaaccata
     3061 ttaacaaaat cagcttcacg ttcaccgttt tggtctttgt aacgacggtt gacagcgata
     3121 gttgctcgcg ctaccgactt gtcattgttg gttttgtgca attctggtgt agacgttaaa
     3181 cgcccaatca tgataacttt attatacata ttttcttcct cctacttatc tattcgtagg
     3241 aaatcaaaaa aagttacaga aatttgtaac ttttcgagga aatttcttat tttttatgaa
     3301 tcatgaaacc tgtcgcctgt tgattggcca taatggtcat atctgtaatc tgaacacggc
     3361 gaggctgact ggtcacatag actactgtgt ctgcaatatc ctgagcttgc aaggcttcta
     3421 ttccttggta aacggacgca gctcgttctt tatcaccatg aaaacgcact gtagaaaaat
     3481 ctgtttcgac aattccaggc tgaatggtcg tcaccttgat atccgttgcg atggtatcaa
     3541 ttcgcagtcc atctgaaaag gtcttaactg ccgccttggt ggctgagtaa acagctgcac
     3601 cagcataggc ataaattcct gcggttgacc ccatattgat aatatgacct tgattggctt
     3661 ttaccattgc tggcaagaaa cagcgagtga ctgccatcaa acctttgaca ttggtatcca
     3721 acatggtcag catatccaac tcttcatagt cttgataggg agctaagcca agagccagtc
     3781 ctgcgttatt gaccaggatg tcaatctgac ctatcgtttc taaaatatca gagcagacag
     3841 tctttactat tgtcatatcc gtgacatcta ggagaaaagt ccaaactgtt tgatttggaa
     3901 aagtttctgc aaactccgcc ttaagagctt ctagtctgtc tatccgtcgt cctgttagaa
     3961 cgacatcctc accctgctcc agataagcac gcgcaatcgc ttcaccgatt cctgaggttg
     4021 ctcccgtaat cactacattt tttgccatct tatttccttc tatcagatgc tgacaagttc
     4081 ctaggcagtc cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt cttctgataa
     4141 ttcaagcacc ccacgttttt gcggagcatt tggcaaatgc aattcacgag gactacacat
     4201 catcccaaaa ctcttttcac cacgaagttc gcctgggaaa atgaaattcc cttttggcat
     4261 catggcacca ggaagagcca caatggtttt caacccaaca cgcgcattag gtgctcctgc
     4321 aacgatttgc actatcttgt cacttgcgac tgcaacttgg cagatgttga ggtggtcact
     4381 gtctggatga gctaccatct cgacaatttc accaacaaca aacttaggtt ccttatcatt
     4441 aacaatttct tctgtaaaac cttccgcctg taattcttgg ttcaaacgag cgacttgctc
     4501 atctgataaa aagacttgac cgcgctctgc aatttcaaac aagctcgaaa cctcaaaaat
     4561 gttccaagct actgtttccc cattttcttt gaggaaaaca cgggctacct tgcctttgcg
     4621 ttccatattc agtttggcat ctccgctatt tttcacgatg accataagga catcaccgac
     4681 atgttctttg ttatacgtaa aaatcattgt ttcctttttc tcctatttca atcctgctaa
     4741 aaaatcgtta atttgctcct tacttttacg gtcgcgattg acaaaacgac cgatttcctt
     4801 gtccttttct agaacaacaa ggctaggaat tccgtaaaca tcccagagtt tggccaaatc
     4861 catatactga tctcggtcca ttcgaataaa ggtgaactct ggattggtct cctcaatctc
     4921 tggtaaggca ggataaatat aacgacaatc gccacaccag tctgccacaa aaaggaagac
     4981 cttcttgccc gctttttcca ctaaagatgc taattcttct aaacttgctg gctgtatcat
     5041 aagacttcct cctcatagac taggtcttca ttttcataga caaaggtata atgacggcca
     5101 tcctcaaaaa tgacgccacc aaccaagctc tccagactgc tttcgtaaac ttgaacatag
     5161 aaggtcgcaa tttcccccat gtcggaaaaa tggtctcgca caatctctgt caactcttcc
     5221 tgagtcttca tgagcttacg gtcatctgca acttttttcg tggcaagagc aaggcttccg
     5281 atacctagca gagccaagcc tgccatccac atttttttag ctttcatacc attcatttta
     5341 acacaaaaaa ggcttcagga caaatgagga agcagcagaa aagcaagtaa aaagcctctt
     5401 cctttaagga aaaggacttc ttatactaag agcaaactag gaagctagcc gcaggctgct
     5461 caaaacacgg ttttgaggtt gtggataagg cgacgctgac gtggtttgaa gagattttca
     5521 aagagtatta ttcttattgc caggcgcctg agttgccaac gtagtaacca tcaggtgtgt
     5581 agatattgcg aagcatctta cctgatgaag ctagataata ccacttgcca ttgtctttga
     5641 cccaatcatt cgctagcatg gctccagaag aacttacata ataccattct cccttgtcat
     5701 aaacccaagt gcttgctttc atggctcctg agcaattaaa ggttcaaaaa actgtccaat
     5761 atcattcatt tttttaaagc attttacact acatcatcca cgctgtagga catagataca
     5821 tcaaatgtaa gagccaaaat atcgaaaaat atacaacttt taaaggcaac atttcatttt
     5881 ttaaagtcta acaaccatag aactgaaatc agagcaaggc atcaacttcc tactcttagt
     5941 acgtctattt tgatggttga agtgaagatt ttttatttaa cgtagacaat ttccaacttc
     6001 ccaaaagcca catctccacg gataatcaag gttttgctgg ttggggctac aggagcgtca
     6061 gccttagctg caccaaagga ggtttctact ttcaaatcta cacgccagtg ttgtggaaca
     6121 tagacggttg catttccgaa ggccacttca atatttaaag ttgcaaaatc acctagcatc
     6181 tctgcattat catagtagat tttagcatcc ccaaaagcga cttccacttg gtcatctacg
     6241 agatcttgat cttgcttata gaaggtcccg ctaccaaaag cgacttcctt atccgtgacg
     6301 actgtttttt tcccattgta ccaccatttt ttttcattcc agaacttact tgaatgcgtc
     6361 agataaccaa caccaagtac caccaagatg ctagcccaaa taagagaatg attggtaact
     6421 ggtaacaagt cataagcgta atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc
     6481 gaagtgagat gacgtctaag gatggactca atggacttat aagcaaaaaa aacaatacct
     6541 agtaaaggcc atattttacc atccaaagaa ggaattccaa aattcccttg cagcaagatc
     6601 caagctgcta aaaccaataa aacaatacca aatgctttct ttttcatgtt ttttacctca
     6661 tgtttcttag attttctttt aggagggatt ggtaatgccg tgagacatga acctccttgt
     6721 gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact gagtaaatct
     6781 gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc aagatagact
     6841 ccaactcata gagcttgagg cgaacctcat aagcttcctt ctggttatga gcgtagatct
     6901 tgctcccttc tgtttcaaag aagagaattt ctgacaggtc tagataatat tcacctgtcc
     6961 ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa gagccgttgc aagtctgcaa
     7021 tttcatctgt caaagtgggg gtcttgatga caatttcagt ctcctctaaa ttgccgtcaa
     7081 tctcaattcg taacttcatc acatctcctt tctgactcta ctatatcaaa gctaagttag
     7141 gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg taggactagc
     7201 ttaacttaca tgtcagaata ggaagaaaag gaatccccac accaaaccac aagcatagcc
     7261 aaccaagaca tccttgggat aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc
     7321 tgaaaagatc aagcatacta agccaatagg tagactagca tgcagacagg ccatggagat
     7381 gatagttgcc gaaaagacat ggcgactggg catcgaccgt cccgaactat ccttatcaag
     7441 aaggggacag atatcccaag tttcataagg tctcgggtga ttgattttct tacgaaacag
     7501 ggacaaggcc acaaaacctg atgcaggaat aagcacataa accccaactt gctgaccaag
     7561 tcctagttgc aggtaagtgg tgactagcaa gatcagatag accaggggca tggcgactgt
     7621 catcaaacga ttgaaactgc gtaataggaa taaaagaatt ggacgactag ttagtctgga
     7681 gctgatattt cgataccatt cttgataatt tttcatttat gcttctcata cttttctaga
     7741 acttgttgag atgttttccc cttggcaagc caatccacta gcttgtccaa gcgacgtatt
     7801 tcctgcatca gaggatcatc aatttcctca atacggacac cgcaaatctt ccctgtaatt
     7861 gcaattcgtt cagggacata atatggtgct tgtctaaaaa aatctccgta agtaacatcc
     7921 ctatccagac aagcaagaac atcactcact tcataccctg tcaaccaact ggtcacttgg
     7981 tgaactgact ctgcctttcc accctttcgc tcaacttttg caatcaaggc taagtagaca
     8041 gcagcaaatt tcatattgta taatttctga ctcatacttc tctctttcta tgtgtactag
     8101 tataaataag aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct gcttcatctt
     8161 ctgtaaattg actattgtac aagtcagcgt agaagccacc ttgcgccatc agttcctcat
     8221 agttgccttg ctcgatgata tttccatctt tcatgaccaa gatcaagtct gcatttcgga
     8281 tggttgacaa gcggtgggca atgacaaagg atgtgcgtca ttccatcaaa cggtccatgg
     8341 ctttttggat caattcctct gtccgtgtgt caacagaaga agtcgcctca tccaaaatca
     8401 aaagcggtgc atccttaaga agggcacgag caatagtcaa tagttgtttt tgtcctacag
     8461 acaaggtcac ggtgtcatcc aagatggtat catagccatc tggcaaggtc ataataaagt
     8521 ggtgaattcc cacagcctta ctagcttcca tcattcgttc atcactaatc cctatttgat
     8581 tatagatgag attgtctcga atagttcctt caaagagcca ggtatcctgc aagaccattg
     8641 aaaaggcatc atgcacttct gaacgcgtca tagccttggt atccacacca tcaatgcgaa
     8701 tacttccctt atcaatctca tagaatttca tcaaaagatt gacaatggtt gtcttaccag
     8761 ccccagtcgg cccaacaatg gcaacctttt gaccagcatg agctgtcgca gagaagtcat
     8821 agtcttgaac attgacaccg tccaccagaa tttctcctgc tgacacgtcg tagaaacgtg
     8881 gaatcagatt gaccagagtt gatttaccag aacctgttga cccaataaag gccactgttt
     8941 gaccagtttc tgctttaaag ctaacatgtt caataactgc ctccgaattt gccgcatagc
     9001 ggaaggtcac atccttaaac tcgacctgac ctttgaagtt ttcatcagtc agctgcactt
     9061 gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg attaatccgc ttagcagaga
     9121 ccatagttcg gggaagaacg atgaagagtg ctcccatgag aaggaagccc atgacaacct
     9181 acatggcata agacatgaaa acaatcatgt cactaaagag aggcagacgc gctatcggag
     9241 cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc tacactcaaa ccacttgaaa
     9301 tccccatcat gataggattc aaaatagcca taagacggtt gacaaacaaa ttcaaacggg
     9361 tcaattcatc atttactgct gcaaattttt cattttgata atcctctgca ttgtaggcac
     9421 gaacgacacg aatacctgtt aaactctcac gagtgatact gttcagttta tctatcagcc
     9481 cctgaatcaa ggactgtttt ggaaagtcta gcgtcatcaa aacggtcgtc atcaggacgt
     9541 tgacaatcac tgccacaagt acggcccaaa gccagtattc tgaatgacct aaaatcttcc
     9601 caatagccca aatagccata attggaccac gcgttaccac ttgcaagccc atagtaatca
     9661 acatttgaac ttgagtaatg tcattggtag tacgcgtcaa gaggctagga attgaaaatt
     9721 tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa aatatcactt ctcagcctac
     9781 tagtataaga agccgccact cgggatgcaa aaaatccaac tgcaactacg gacaagaagg
     9841 caagaaagag cattcccatc atcatgcttg ccggctgcca caactcatct aaattagttc
     9901 cttgactacc tagcaaatcc gtaattttcg agatataggt cggcacttcc aactctagat
     9961 agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat ccccattctt ttctactaat
    10021 tcttttggct aatttcttta ttctctcctc ctattccctt gatattttgc ctgtagttga
    10081 ccgagaactt tctcaaaaat cagtaattca tcttcatcaa tgtcttccat caactgcttg
    10141 tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt gtccgtcaga
    10201 cgaacaaact tagcccgctt atcaacagga ctcgcctcca attccaccaa accattttgc
    10261 actatacgct taaccagatt actagcaaca gacttggtaa tattgagttc ctgctcgata
    10321 tctttaatca agaccaagtc ttggtttttc tcgcgattat ccaaaaaacg cacaacctga
    10381 ccttgcggcc cacccataaa ttcaatgccg caacgtttgg cttccttttg caccatcagg
    10441 taaatttgat gaccaaaacg cttaaagact aacatcggtt tatccataat ctcccccttc
    10501 taaataaaaa tagttctctg gagaataatt aaatttctat gagaactatt ttcttgatta
    10561 aaaaaatccc aagtgatttt ctcacttagg atcatgttct ataggttaaa ttaaaaccca
    10621 tctacgttcg tataaatctt ttggacgtct tcgtcgtctt caagaacgct gtaaagtttt
    10681 tcaaaggttt caaggtcttc gcctgacaat tccacttctg actgaggaat catttccaat
    10741 tcagtcactt ggaattcttc aataccagac tcacggagag caacgatagc cttgtgaagg
    10801 tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc atccacatcc
    10861 acatccgctt cgagcaattg ctcaaagact gcgtccgcat cttcacctcc aaatacaata
    10921 acacctttgt tgtcaaaaag gtaagaaaca gaacctgaag cgcccatgtt tccgccgttt
    10981 ttaccaaagg ctgcacggac attggctgct gtacggttaa cgttagaagt caaagtatcc
    11041 acaattagca tagagccatt tggcccaaaa ccttcgtaac gtccttctgt aaaggtttcg
    11101 tctgtgtttc ctttggcttt atcaatcgct ttatcgataa tgtgttttgg cacttgggct
    11161 tgtttagcac ggtcgataac gaatttcaaa gctgagtttg attctggatc tggatcacct
    11221 tttttagctg ctacatagat ttctacacca aattttgcat atactttaga gttagctcca
    11281 tctttagccg ttttcttggc tacgatattg gcccatttac gtcccattag gaatctcctt
    11341 ttttcacatt ttaatctttc ttattataac acaagttttt ttgattttca ctagaggaaa
    11401 tggattttat tagcaaatca agctaggata gtactttacc tgctaagatg gtcttgcctt
    11461 tctatcttta tcaacagaca ctcatccaca ttcaaaaaac aaactagacc attatctgca
    11521 aatagaaagt ttcagccaag tttgacaaag tcagctcaaa ttactgtttg aagtttgtag
    11581 atataagcga caaaaacaat catactgcac cttttgttga cagtctactc cagacatatc
    11641 atagttccag taaatacttt gaaatccaac agttcttata ggcgctattg tattctaaga
    11701 aatcaataga agagtttcta agcaaacctc taatactcaa taaaaatcaa agagcaaact
    11761 agaaagctag cctcaggttg ctcaaaacac tgttttgagg ttgcggatag ggctgacatg
    11821 gtttgaagag attttcaaag agtataattt acgtgttccc aagatggaga agttagacta
    11881 gtacactggc acttctaaac cattgctagc aattgatttg ttcatattta atttcatttt
    11941 ttccataaat gggtattaga tataaacagc aaaatatttc cgatacgtgt cgttcttgaa
    12001 tttccaatca tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa ggaattggct
    12061 acccttttta cttttttaca cattctgttt gatagattca ttttaacatc acgagcatac
    12121 tccaatggaa atcgctaggc aagagataaa ctttcagata tccgcagaga gatcatcgcc
    12181 tctttttgtc gcaagcattc tcctctccta gtcattttct accttatctt ctacctgagg
    12241 atagagagtt gttccccaaa tagaaatcgt ccgcttacgc actagtggca aatcggtttt
    12301 ttcataaacc gtacgccacc attcccaggc aagcccggta cactctctaa ttttgacaga
    12361 gagattacga acattccctt ttaaaggaat actagtggta aagtgagccg ttaaatcctg
    12421 cccatttctg tcccaagcct taggagtcaa gacttcctta ccttgatgat cataggataa
    12481 ttcattccaa gtaatataat attgggcaac ataggcacca ctatgatcca gcagtaaatc
    12541 tccgtttctg taagctgtaa ccttagtctc aacatagtct gtactatttt gaaaggtcgc
    12601 aactacattg tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg gatgatctgc
    12661 tgtaaagcga ctgccttctt gaatcaagtc ctctaccata tccaccttgc ctgttacaac
    12721 tcgggcaccc gaacttgggt cgccccctaa aataaccgcc ttcacttctg tattgtccaa
    12781 aatctgcttc cactctgtct gaggagctac cttgactcct tttatcaaag cttcaaaagc
    12841 agcctctact tcatcactct tactcgtggt ttccaacttg agatagactt ggcgcccata
    12901 agcaacactc gaaatataga ccaaaggacg ctctgcagaa attcctctct gttttaaatc
    12961 ctctaccgtt acagtatctt gaaacacatc tcctggattt ttaacagcgt ctacgctgac
    13021 tgtataataa atctgcttaa aattaacaat ctgaatctgc ttttcgcctg aatggacaga
    13081 gttaaaatca atatcaagag aattccctgt cttttcaaag tcagaaccaa acttgacctt
    13141 gagttgttcc atgctgtgag ccgtgatttt ttcatactgc attctagctg ggacattatt
    13201 gacctgacca taatcttgat gccacttagc caacaaatcg tttaccgctc cgcgaacact
    13261 tgaattgctg gggtcttcca cttggagaaa gctatcgcta cttgccaaac caggcaaatc
    13321 aatactataa gtcatcggag cacgatcgac cgcaagaaga gtgggattat tctctaacaa
    13381 ggtctcatcc actacgagaa gtgctccagg atagaggcga ctgtcgttgg tagctgttac
    13441 agaaatatca cttgtatttg tcgacaagct ccgcttcttt ctttcgataa caacaaactc
    13501 atcgggtagc tgattaccct ctttgatgaa acgattttca atactttctc cctgatgggt
    13561 caagagtttc tttttatcgt aattcatagc tagtataaag tcatttactg ctttatttgc
    13621 catcttctac ctcctaataa gttcctggat tgagttgcat aaactcagac ttgttcagcg
    13681 aaatcagccg tggttggact aagtgatcca aaatttcctc gtacaattct tctgagacat
    13741 tgcgtcgccg tctggctaga taagaagtcg gaataaccgt attatccaac ataaatacct
    13801 tatctaagtc aatcaaggtt ggtcttgtaa aaggattacg agctagatcc ggctcttcta
    13861 tcataaagtt cttgaccaaa cgtctggtca agagagctgg tttgaaggtc tgatttttaa
    13921 ccaactcttt gtttttagtc atgctgttgt caatacagat atacatatga ttcttcacag
    13981 ccaaatcgct actaatagtc ggaaaaggca aataaagagc tacaacatct cctctcttaa
    14041 tcaagcaaga gcaccccctt ttctcctaat gtaacataga caggattgac caagtcttct
    14101 gattgactca gaatttccaa agtttgagtt tggcgcgctg tcaatttagt agcatcttgt
    14161 ctcttcaata caaaatgctt gtcgccaata accttgacaa tataatcctt ctccaaagct
    14221 gactggtaaa tccacatcag atgttgtctg tcctgagaac tcaagagaga aggattttca
    14281 agcctcccga tagtctgata aaaatcaaaa acaggagcta actcctgcca atctgattgg
    14341 ctagttgtca aggctagaaa aagggctttg cgagctgata cttcttggtt agccttgaga
    14401 gttactttcc cctccaagtt ttttagaaat cgggaaactc cagaaagcaa atttttctct
    14461 aactgcgaga aataaaaacc tttcgttccc agacataagt ctttcatgtc gctttctcta
    14521 gcaaataaga gctcaaacat ttgatagtaa aagaaaaata tctggcactg ggtcgcgctc
    14581 atcttttcct tatcggcttc tttttttaac cagagcaagg gcgacaggta gctggattga
    14641 gacatttcct ctacctccta ctctttttta actggagcat ctgcactagc tgccacttct
    14701 tttgactgga tactttccca ctggttaatc tcctctgaga taagaccttc gcatgtcttg
    14761 acaaataggg caaaagcctt ggtctttcct gcatatttct ccgtttggca ttgatagagg
    14821 aatttttctt tctccaggag ttgcgcagtt ttttggtaag aaatccaatt ttcctttgca
    14881 ttatacaaat tgataatccc ctcacacagc aagccgagac tggataaggc aaccgaaatc
    14941 aaacggtagc gatcacctgg cataggaata gcacaaaaga cagctatgag gaaacctgcc
    15001 acgatttctg ttatttttaa taccttatag cgcctacgat gttgaacgct tttctttaaa
    15061 aaatgagcta tctgtacgtc taatcgctct gtcaggtaca tttcttctgg cgtcatattc
    15121 gtaactcctt tcatttactt tgataaccat agtataacat atttgaatat caaagtatag
    15181 taaaaactgg actataactt attagacttc ctgcgaaaca aaatatggta tagtagttct
    15241 atgaattatg aagcaagtaa acaactaact gatacacgat ttaagcgtct tgttggtgtt
    15301 cagcgtacca cttttgaaga gatgttagct gtattaaaaa cagcttatca aaaaagtcgg
    15361 acaagctggt aaaatcttgg ctgacagtaa ttatcaaggg ctcatgaaga tatatcctca
    15421 agcacaaact ccacgtaaat ccagcaaact caagccgcta atagctgaag ataaagccta
    15481 taaccgtgcg ctatctaagg agagaagcaa gattgagaac atctttgcca aagtaaaaac
    15541 gtttaaaata ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa
    15601 tttgagtgct ggtattatca atcatgaact aggattctag ttttgcagga agtctattat
    15661 atatatgcac agacatatga aatctttttg atacagcctt ctttttacat agagagacag
    15721 cagttatgat atatttatcc atacacaaca tcttctgtac caatactaca atattggtac
    15781 attttgatta cacaatcgtt tcaaaaaata tgatggaagc ctgagtattt tatagtaatt
    15841 cccttcctat caactagatc aaccagttga gtgttgaatg ttgaaacacc ctagcctcag
    15901 caaaggacta tgatcagcat ttcctagcca ataggacgct ccaaatcacc tattctaagt
    15961 ccataactag cttggtcagt aagatacaga ctgcaaggcg agactgacgt ggttgatgag
    16021 atttttgaag agtattacaa tcatagattc accagtagac ttgaacgcag atttaactat
    16081 agtagattga aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg
    16141 actgtcctga tcaatttgtc ctgttctcgt ttcattttac tatactaaaa aaccacctga
    16201 aacaaatcaa gtgactagag gataaaaaca aagactgggc aaaaagtttt gaaaagcaaa
    16261 aaacgcataa tatcaggtct tgaaaaacct tgatactata cgtttgattg tgggaagatt
    16321 gacttcattt tctcctgaaa ttgaagtttt ttctagtttc cagatataga cgaattcaat
    16381 atagccatct cgctacaatt attttaacca tcgagaaaat ttttcagaat ttcaaaaatt
    16441 tcattttgat ccaatgaaat gtcatcattt tgaagaatag ttgacttcac aggctctaat
    16501 tctatcacaa agcggtgcat gtctgctttt accgcactac ttgatgttat agccgataac
    16561 ttttcatctc ctagcaagga agctgtcaaa cgggtaaggt cattcaaatg ctttttaatg
    16621 gacttactta aatcttgagc acctgtagca gagcgctctc tcatatccag ccaagcttta
    16681 gccttaaaaa taatt
//
LOCUS       DBEJNA010000043        16129 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEJNA010000043 DBEJNA010000000
VERSION     DBEJNA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16129
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.43"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(166..2271)
                     /locus_tag="ACL3JB_001770"
     CDS             complement(166..2271)
                     /locus_tag="ACL3JB_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0686453.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLAAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQAIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(2880..3860)
                     /gene="mraY"
                     /locus_tag="ACL3JB_001771"
     CDS             complement(2880..3860)
                     /gene="mraY"
                     /locus_tag="ACL3JB_001771"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0686454.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3862..6114)
                     /gene="pbp2X"
                     /locus_tag="ACL3JB_001772"
                     /gene_synonym="pbpX"
     CDS             complement(3862..6114)
                     /gene="pbp2X"
                     /locus_tag="ACL3JB_001772"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0686455.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(6118..6435)
                     /gene="ftsL"
                     /locus_tag="ACL3JB_001773"
     CDS             complement(6118..6435)
                     /gene="ftsL"
                     /locus_tag="ACL3JB_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0686456.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6447..7397)
                     /gene="rsmH"
                     /locus_tag="ACL3JB_001774"
     CDS             complement(6447..7397)
                     /gene="rsmH"
                     /locus_tag="ACL3JB_001774"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0686457.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7563..7757
                     /locus_tag="ACL3JB_001775"
     CDS             7563..7757
                     /locus_tag="ACL3JB_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0686458.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7773..8315
                     /locus_tag="ACL3JB_001776"
     CDS             7773..8315
                     /locus_tag="ACL3JB_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGR0686459.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8326..8568
                     /locus_tag="ACL3JB_001777"
     CDS             8326..8568
                     /locus_tag="ACL3JB_001777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686460.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8579..8914
                     /locus_tag="ACL3JB_001778"
     CDS             8579..8914
                     /locus_tag="ACL3JB_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686461.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(9024..10025)
                     /locus_tag="ACL3JB_001779"
     CDS             complement(9024..10025)
                     /locus_tag="ACL3JB_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0686462.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(10085..11986)
                     /locus_tag="ACL3JB_001780"
     CDS             complement(10085..11986)
                     /locus_tag="ACL3JB_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0686463.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMESCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSKDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(12008..12301)
                     /gene="yajC"
                     /locus_tag="ACL3JB_001781"
     CDS             complement(12008..12301)
                     /gene="yajC"
                     /locus_tag="ACL3JB_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0686464.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(12301..13119)
                     /locus_tag="ACL3JB_001782"
     CDS             complement(12301..13119)
                     /locus_tag="ACL3JB_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0686465.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(13106..13885)
                     /locus_tag="ACL3JB_001783"
     CDS             complement(13106..13885)
                     /locus_tag="ACL3JB_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0686466.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(13900..14391)
                     /locus_tag="ACL3JB_001784"
     CDS             complement(13900..14391)
                     /locus_tag="ACL3JB_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0686467.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(14402..15592)
                     /locus_tag="ACL3JB_001785"
     CDS             complement(14402..15592)
                     /locus_tag="ACL3JB_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0686468.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGETREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(15604..16038)
                     /locus_tag="ACL3JB_001786"
     CDS             complement(15604..16038)
                     /locus_tag="ACL3JB_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0686469.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         4690 a         3655 c         2852 g         4932 t
ORIGIN      
        1 tcaaggactg gttttgatat agcacgttta agtaccgact tctgagctac tatagtagat
       61 tgaaactaga ataatacact tctactatac gacatgcccg tcgtacctca aaaggaacca
      121 gtttttttca gctggctcct tcttttttat cctcaaaatt ctatcttagg ctttctcacg
      181 aataaccaaa acgccatctt ccatatctgc ttccagatgt ttagcatcta aatgatccaa
      241 gtggaagtct gtcaccttat cacgaatttc ttgttcaacc actcgacgga gaggacgaac
      301 tcccatgact tcgtcgtaac cttcttctgt gatataatct ttagccgctt gactgactac
      361 caagtcaatg tctttcttag ccaaggtttg gttaacttca gccaacatca aatctacaat
      421 cttagaaagg tcttccttag tcaagtgtga gaattcgatg actgcattaa agcggttgag
      481 gaattctgga cggaagaagg gtttcaaacg gtccatcaat tctggtttat ccgcatcttc
      541 tgtcaagttg gcttcatagc caaatccagc atttgaggtc gcaataatga cagtgttctt
      601 gaagtttact gtatttcctt gaccatctgt caaacgacca tcatctagaa cttggaggag
      661 aagggtaata acttgagggt cagccttttc aatttcatcc aagagaatga tagagtatgg
      721 attgcgacga acacgttctg ttaaggtatt gctattgtca tcataaccca catagcctgc
      781 tgttgtacca attagcttag aaacagctgt gcggtcactg tattcagaca tatccaaacg
      841 gataatcgca tcctgggttc caaacatatc gagtgccaat tgcttagcaa gctccgtctt
      901 accaacccca gtagacccta caaagaggaa gctgccgatt gggcgatttc cttcatcaaa
      961 accagcacgg ttacgacgga tagcacgagc tacagcttct acggccttat cttgaccaat
     1021 caccttgtct tgcaagcgat gagccatatc tttcaaacgt tcgatatctg aagctcccat
     1081 ttgcgatact gggatacctg tcattcgttc cacagattca gccacatcgt tgacacttgc
     1141 agtcactttc atatcttctg tgtggttttc gattttcttt tccaattctg caatgcgtgt
     1201 tttatagttt agagctgctt caaaatcttc tgcttcaact gctttttctt gcttgtcttt
     1261 ttccgtttcg atttctcgtt caacagcatg cacatctgtt actggatgtt gagccgccaa
     1321 gtgagcagcc gttacatcga caaggtcaat agccttatct ggcaagctac gttgaggaat
     1381 gtattgaaca gaataatcca ccgctgcttt caagacttcg tctggcaaga tgacattgtg
     1441 gtgttgttga tagaggtcac gaatggcttg aagaatttta aaagtattct ctgctgaagg
     1501 agcattgacc ttcacttcgt tgaaacgacg agcaagagca gcattcttca agatggtgtt
     1561 acggtattcg tcttgagttg ttgccccaat cactgtcaat tctccacgag agagagctgg
     1621 cttgagaata tccgcaagtc ctttagaacc actgtctcca ccagtgctac cagcaccaag
     1681 aatttggtga atttcatcaa agaagaggat aatattccct gcttctttca cttcattgac
     1741 taagttttgg acattttctt caaagctacc acggtattga gtaccagcct caagacctga
     1801 gatatcaata gaaataattt ccttgttctt gatagcagca ggaacatctc cgttcacaat
     1861 ggcttgcgct agaccttcga caactgctgt cttaccaaca cctgcatctc cgaccaaaac
     1921 aggattgttc ttggtgcgac gtgagaggat ttcagatgtt tcttgaattt ccttgtttcg
     1981 tccgataaca ggatccaact tgccctcacg cgcttctgct gccaagtttc gacctagttt
     2041 tgcaaggaca ccgtcttgtt tcatacctga tgcctgttgt ggcatttgca catcagtttc
     2101 tgcatttcct ggtaattgac cagtcgcacg atagtgagca aattcctcag gtgtgacttc
     2161 gcgtccatta attaagtaac ggcgattttc agaactatat cctcgcatac cacccatcaa
     2221 ttggttaaat aaatcatcca tgttattaaa attattaaag ttgttattca tattctttac
     2281 ctctttttgt ttacttagtt atgactactg atattgacta tctttgacca ttgttttaaa
     2341 aaatttagac tagctaaacc gctaccctac gtactatttc tggtttttct ttttcaagca
     2401 ggagtagact atctttactt ctgaaaattt ctagatgaaa catagaccca cctctttcta
     2461 ttttacttta aataagtgtt ctagtaaggc tttcatttac cttacgttca taatatacta
     2521 cattggtcag aaaaggtcaa gagttttgac tttaactgac caatattttt ttacactctt
     2581 cgaaaacctc ttcaaaccac atcagcttct ccttatctac aacctcaaaa ccatgttttg
     2641 agctgacttc gtcagttcta tcaaccatct caaaactata tattaaaatg aaataagaac
     2701 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tattttagaa gcagatgtgt
     2761 actattctag tttcaatata ctatattttg agcagcctaa agttagcttt ctagtttgtt
     2821 ctttgatttt cattgtgtat ttaaatacaa aaacaccctg aaacatcagg gtgccattct
     2881 tacattaaat acaaaattgc tagggtcagg agacttgcta gaagtcccac tccccaaaag
     2941 aagaagtcaa ccttccactc gctccaagga tttcctttac cagacaatcc cccaagctca
     3001 aaatggtgat gtacaggcgt catacggaaa atacgtttac cacctgtcag tttgaaataa
     3061 ctgacttgca tcataacaga agttgtttca aaaacatata caattccgat aatcaagaga
     3121 gtccattctt ggtggagagc catagagata gctgccagca tcccacctag ggccaaactt
     3181 cccacatcac ccataaagac cttggcaggc ttatggttaa agatgaagaa accgagcaaa
     3241 ccaccaatca tggcaagaat cactagaaga atatccatct gaccttgcac ataggcaata
     3301 actccatagg cagacaaact aatcacaacg gaaatactag ctaaaccgtc aacaccgtct
     3361 gtcaagttta ctgcgtttga aaaaccgact agccagaaaa gagcgaagaa aatatagaaa
     3421 aatcccaaat gaactggata accaaagaca gacaggatat cgccaccgcg ctcatagaaa
     3481 agatagaaga taactccacc tagaagctga agagctaatt tttgcttagg attaagcccc
     3541 tcattgattt tacgaaagac cttgagaaag tcatctaaaa atccgaccaa gccatacaag
     3601 accaagatga acaaaatcat tcccacatta ttgctgaatt ggctactaaa tagggcgaaa
     3661 aagaaagcaa ccaaaacaga agtaatcaag aaaaccaaac ctcccattgt aggagtccca
     3721 gcttttgcct gatgctgttt gacatcctca tgcatctgct ggcctgtaat ttgcgccttt
     3781 ctataaaatt ggataaaggc cggaatttct actaaagtta gtaaaaatgt cacaattcca
     3841 gcactgatgg aaataaacat attagtctcc taaagttaat gtaatttttt taatgtcctt
     3901 gatagctgtg ttagcacgaa catcttgctt ctgcacagta gagcccgaac cttgaaattc
     3961 aagttctata ttgagccact tagcaagggt ctcagcagtc tcctttgtcc aaccatacat
     4021 atctggaacc tcctctgctt tatcagataa gataaggact tgctggttcg gggcaagatt
     4081 cttcccttct tcagcagaac tgtttttaat cttcgttcct gttcccacaa cgatgggttg
     4141 tacaagattg cgacgcaatt cttctgctaa atcaccaggt gaaatatcct tgacactagg
     4201 cataggataa ggactttgtt gacttacttg ctctaaagcc ttagctgttg tttgaagatt
     4261 gagagagtct ttcatagctg aagcccgctc caagatagga ttggcaaatt ctcccaactg
     4321 aatacctgaa taatgttcag gttgttggac cgtcacatac aagataaaat caggattttc
     4381 agccggactc atcgatacag ccgagaaaat atagtcggtt aacccgacta gataaccacc
     4441 atttttctcg tcagcaatct gagccgtacc agacttgagg gctacatttt gcccaggaac
     4501 agttacagtt ggcttgcctg tgctgtggtt atacatggtt ccataaaccg gatccgtccc
     4561 taccaaaacc atgttagtcc gagttagact agctgcatct ttagaaacag gatttcccac
     4621 aatttctttt tgagatttcc gagcagtttg atcatttgga tcataaatgg cactaataaa
     4681 tttaggctcc agcatgacac cgtcattagc aatagctgta aaggcacgaa tcatttgcgt
     4741 ctgggtcact gaaatccctt gtccaaatga gctttgcgca atgttgacaa tattatccgc
     4801 aggaagctga ccagcatact catccgtcaa accgaaacgg gtcggaactc caaatttaaa
     4861 acgattaaga taatcaagcc aggtagcatc tcccatcttt tgctcaagga gagtcatccc
     4921 aacgttactt gagtgtgcaa aaccttgaga aaaagtcatc attctgccac cagtcaatcc
     4981 ttcattaacg tcccaatctc gaatcgtggc atctgcaatt tttaactcac tactattaaa
     5041 gacttctcct cctggaaagg tattattatc aatagcagca gccaacatca tcactttcat
     5101 agtggaacct ggctcatagt tactttggta aaggatatca cgccaaacaa agtcctctgt
     5161 aatgccttct tttgtatctg catcaaaggt cggtcgttgc gttgttgcca gaatttcccc
     5221 tgttttagca ctgaccaaag tcgctgtcat gtactttcct tttaccttct cttgaaaagc
     5281 atccatctgg gtttccataa aggactggag ggggctggaa atggttgtat aaacatcctt
     5341 accgtccatc gttcgttggg aaacttgttc tgttccgggt acaatattac ccagacgatc
     5401 cttttcatag gtaataatgc cgtctgtccc tgcaagaata ctgttcaagg aactctccat
     5461 tccagaggtt cccagcaagc tcttgcttcc atcttcattt tcatggagct gagctaggcc
     5521 gataaaacta gaagcaaatt gtccgtttgg gtaactacga ttgggactgg ttgtaaaatc
     5581 aatccccttg acctctgcag cttccaattc ttttttgata gacatcatat tggcataggt
     5641 aatcccattt ccctttgctc caaaggaaac ttgcttgaga ttaggttgcg agagttgctc
     5701 tcttacatag gattcttcca tgtccagata cttatgaaag acctctgcaa ccttgttaaa
     5761 ttgtgttttt tctacgtaaa gaatcttacc cgttgctgac ttatagttct catcaatgac
     5821 cgcatagaca ttataggagg ttgcatcctc agcaatcggg actccatttc ggtcataaat
     5881 agtcccacgt ttggcaggaa ctgtacgggt ggtttgatga accttcttag cttccttcgc
     5941 taaatctgtt ccaaagcgag tgcctgtccc aataatgacc gcaaaattga ctaaaaaaat
     6001 ggcaaaaaca aagacagata ataaactcag actttttcca actctgcgtc tgttttcagc
     6061 cggcgatttc cgatttttgg tcgcataacg gattactctt tttgtccact tcatatctta
     6121 ctccgctatt ctaatatttt cattgtttaa ttgcaaatcg tgtgaattgg caatttcttt
     6181 caaacgttct gcacgtaata gttcattgac ctcttgcttg gcatcgtcca attcggtctt
     6241 cttttcctct atctgcgcat tgatttttgt caaatcattc tgcacttgca agagcttggt
     6301 ctgcataaaa ataatactaa tggctacaat aagagtggtt acagcaatgg aaaagtaaaa
     6361 agctttttcc acacgcgaaa accgtttaag ttgcatctgt agtatttgac ctgttttttc
     6421 cattttttct gccatctttt tccctcttac ttgtgaattt ttctggccac gcgcaacttg
     6481 gctgagtgcg agcggttatt ggcttctaac tcttccgcac ttggcaagat tggcttacgg
     6541 gacaccaatt ccatcttggg cttgagatca tctgggatga aaggcaagcc ttttggaact
     6601 tcaactgttg aagcttcctt gaacaattgc ttggtcaagc ggtcttctaa ggaatgaaag
     6661 gtaatcactg aaattctacc atccagagcc aacatatcca tagcctgctg gatggactca
     6721 tctgccgccc ccagttcatc attgacttca attcgaatag cctggaaaat ctgcttagca
     6781 ggatgcccct tcttcttgag ttccttggca ggtttgacca acttgataat ctctgctaac
     6841 tcagtcgttg tctcaatcgg cttcacttca cgcgcttgct caatcttacg cgcaatctgt
     6901 ttagagaatt tgtcctctcc atacttgaag aaaatacgaa ccaagtcatg atagtcataa
     6961 ttgttcacca cttcatacgc tgtcagacta gcatcctgat tcatccgcat gtccagtggc
     7021 gcatcctttt tataagaaaa accacgctca cgctggtcta attgaggact agacactccc
     7081 aagtcataac aaattccatc aatttcctga acaccagctt cgcgcaaacg tgcctgtaaa
     7141 tgacggaagt tgtccttgat aaaggtcacc attcccttct caatgtaagg tgccaagcgt
     7201 ttttgcgcat tgtcaatggc attctgatcc tggtcaaagg catagagatg gcctttttca
     7261 cttaatttac ttaataaata ctcgctatgg cctgctccac ccaaagtcgc atcaacgtag
     7321 ataccgtcag gttttacgtc aagcatatca atcgtttcgt ggagtaagac cgttacatga
     7381 tgaaattctt ttgtcatatc ttatctattt taccacaaat ccgaccagct tgcacttgtc
     7441 agacaaatag gacaaggaga ctactatttc ttcaaaaaat atgtcaaaaa tacttgacac
     7501 tttatgttta aaagactata atatagtcaa atatatacga cataaatcag aaaggagacc
     7561 agatgaatcg tgtgaaagaa tttcgcaagg aattgggtat ttcccagctc gaactcgcca
     7621 aggatatcgg tgtctcgaga cagactatca atatgattga aaacgacaag tacaatccaa
     7681 ccttggaact ctgtctcaat ctcgcccgca gcctccaaac tgacctcaac agtctctttt
     7741 gggaggaaga tttttaaaaa aggagcaaac tcatgaaaaa agaaaccttc actgaaaaac
     7801 tgatcaaacg cacatacggt atttctggtc cccttgacga atacaaacgg cgtgaggccg
     7861 atcgtattgg gaaccaagtc tttatcgtcc tcttttatct gatgattttc ggaaatatta
     7921 ttccactcct tctggcctat aaataccctc aagaagtggc tctaatctat cctcctctga
     7981 ttttagtgat tgccctcatc gcttctggct atgtcaccta ccaaatgaaa aaaacaggca
     8041 tcacagtcat tgaaccagat atgctgaatg agaaagaaag caagcaacta cactaccctg
     8101 gtctgaaagc aggtttgttc tttggtctat ggatgttttt tataactcct cttctcagta
     8161 tactcataga tgaaggtcag gactattttc attctcttct cactataaga aatggtgtat
     8221 caagtattct cggttctatt ttcttcggag cgagcataca gttcctcatc tcccgtcgca
     8281 ttgcaaaaac taagaaaaat caagatgagg attaggagga aactcatgaa aaaagaaaag
     8341 aaacagttac gttatcctgg tctgaaagca ggttcgattt atggaacagt gatatttttt
     8401 ataattccac tcattgatac cctaacaagt gaaaatccaa attttatcag ttctcttcta
     8461 aatacaaaac atatttttaa aactatactg ggagctttct ttttcggagt gatgatacat
     8521 attgtcgact cacttcgtat tgcaagagct aaaaaagacc aggattagga ggtgccttat
     8581 gaaatcacta gctagactac tgatcattca tgtttttatc agtattttcc ttttcttcgc
     8641 ccttacttca ggagctattt ctcatacagt tttactactc ctactcctct ttcttcctgc
     8701 gctcaataaa ggacttgaga aaatacaatc aaaacggata cctgtcctca acgcagccct
     8761 cttctttctc ctcatatcct ttccacaact tttaaccaac cctgtccaat ggaaattttc
     8821 aatattccta gtcgtaacca tcatttcaag tttggcctac ttctataact tttatcaagt
     8881 agttaaagaa gtagatcaaa aacagttgat ttaggagctt gctcccataa tttctcattt
     8941 tataggcaaa taatcccacc tagcttgttc taggtgggat tattttattt cttaacagag
     9001 attgcaagtc attttccttc attttagaaa gtcgactctt tccaattcac actacaatcc
     9061 aagacttgtt gcctttcttc ttgattgcga ccttcaatct ggtcaatcaa aatctttgta
     9121 gcctgttgtc cttcctcaaa ggagggctga accagcgtcg aaacacttgg agaagaaaag
     9181 caagtccact ccgtattgtc aaaaccaatc aacccaactt gtggcaagtt ataattcaac
     9241 tctttgataa cggtaaagac tagaggtagg gcccaacagt tagggataaa taccagagtt
     9301 ttttcatcgg gatcgatttc tttttgtaaa aattccttaa tttgttccaa attcgtatgc
     9361 ttatcttcaa tggttagact ggcgtggcgc atattagcat ctgttaaagc atccacaaaa
     9421 ccacttgccc gctcaatccg agtactcaaa cgactcgtat ccgctgtaat caagagaaaa
     9481 tgctcataac ctttttcgat acaggactgg gtcatgtcat aaacggcatc atagttattg
     9541 gttttaaccc agctagtccg gtgttcatag agctgactat caaaaaagac cattttcttc
     9601 tttttctcat cgatgatacg agaatatttt cggaaattag aggtcggctg aataataaag
     9661 ccgtctactc ccaagagaag catgctttca atataccggt cctcactctc ttggctgtaa
     9721 ttactatttc ctatcattac ctggtagcca ttctggctgg cgatatcctc aattccctta
     9781 acaatttggt ttgagaaact gttggtaata tcaccgatca aaacaccgat taattttgtt
     9841 cgtttggagt ttaagctacg cgcaacaatg ctcggtttgt aatttgtttc atgaataact
     9901 ttttcaatct tttcacgtgt ctcttgggac attttttcat atttcccgtt taggtaaaat
     9961 gacacggttg ttttcgaggt ctgagccatt tccgcaatgt cttttatggt cagtttcttc
    10021 tccaatctaa aacacctcct actaatactt attataacat attcactatt caaaatgcct
    10081 atttctagca ctgcaagcga atcattctct catttatttt atcatatact agacattttc
    10141 cacgcatttt tgttccgtca acgaggcaca atttttcacc tacacaaata tccttgctta
    10201 ataacagaat cagcttgtct gtttcgtcat ttttcacttc aaaagccaga gcattttcca
    10261 cttcacgatc atctgtctgg tagacagaat gacggatgat ttcaaaactc tcatgcgcaa
    10321 tgatggtata atccagcatc tgattctcaa agaattggcg cttggtgagt ttgctacttc
    10381 tttcaagctc attgtattta ggagaaatga tggtatcttc caaatcaaaa tcaacttcac
    10441 tccatagtct caactgattg attttcccat cttgataggt cacatccttg tcaaggataa
    10501 actgagtcaa cgcctcatgc tgaccttgac acctgatgtc atctaccaag agccagacat
    10561 cctctaccaa catgaggatt tttctcttgt gaagataagg caaatcaggt tctgctgacc
    10621 aataagcccc ttcaatataa tgcactccct ccctttcttt atggtgacaa aacagggagt
    10681 gaggatagta ttcatattcc caggatcccg tgattctttc cggagctttc ccatctacaa
    10741 tgcaggtcga atgactccaa gcactcttta agagataacg ttcatatatc tcccgataag
    10801 aataacgccc agcatctatg aaaataggtt ggccttgata ctgtaagcaa aaactattct
    10861 cgtcactatg gctatgggca cttcctagcg gaccattttt gaaaaataga taacgatgtt
    10921 catccttaat gcagacatgt ccagagtctt caaagatcat ggacctaggc tgccaagctc
    10981 tcttttcaaa ttcctgcagt cgcttgacct tttctcgccc caggaacaag aggctaagca
    11041 aatcgacttt aacatccaga ccgttaagaa ggtcttcctt gttcaaaacc acagcagaca
    11101 ggctcaacat ttctgtcgtt tctgtagaat cgctatcacc aaaagccaaa gttcgtccat
    11161 ctaagcctgt catcatttga atataggtcg ccatcttttc cagcaactct tggtaactat
    11221 cttgcaagtc tggaagcaag agacacaaat ccagcaaggc tttataaacc tctacatgat
    11281 agagaatcga ctgttcaaac tggcttccat ctcctaaaat ctgtgtctca atttgctgtt
    11341 tcaactcctc tgaagcaaaa tggtaagctt cttctaggtc catcttatct gcaaagaaat
    11401 gatagatagc aagcatcgga attgtttgta aaattcccca gttactaagg gtgtacttgg
    11461 cgcgatagtg gcttttcata aagtcaatct gcttttctag actgaccaaa attttctcta
    11521 gttctttctc ctctagcaag tcaaatttca agaggagcaa gagtagtttc aaccaagtaa
    11581 aggaacgaat acccgtatcc aaggttctag tcatcaagga ttgaggagaa aattctctca
    11641 cctgctcaat ccaatcaaat agaaagaact tgcacttttg aatatagtcc ttatctcctt
    11701 ctaccagata ccctatcata aactgcaaga gatattcttg tcgattgagc atataagacc
    11761 attctggatc atcttcaaat acttgatccc ataccatcgg ctggatttga tggatttttg
    11821 aacaagactc catatcccaa ggactatcaa acataaaacg attgtccatc aagcgttcaa
    11881 gggaactctt gactttctca tagtcttttg aacagtggga caagatataa tcacgacatt
    11941 ggtttccatc gactctttca aaaaattgtc ttctttcttc tttcattatc tattaccaga
    12001 aaaagaacta cttaaaaagc agttcttttg tctttcccat tacactttcc ttttctacat
    12061 agatgaccac accttttgca atctgcaagg agaccaagtc atctttgata gaaatgattt
    12121 ttccatgaat tccagacaat aacaacactt catcaccaga tgttaaagaa gctaaatact
    12181 cttgtcgttg ctccatctgt ttgcgaagca acttttgctg acgaatagaa tgaaagcttg
    12241 acagtaaaag gggactcact gccaagacaa tcactattcc ataaaacaat gttgtatcca
    12301 ttaagctata atcttaagcc agcttccgat aattccgatg ataactgtta aaataacgag
    12361 tttatatgtt gtccatttct tttctttgat caagtagtaa actaaaagtg taaatagggc
    12421 tggtagaaga gctggagcaa ccttatcaag cattccctga atacttacga tactttgttt
    12481 agcgtctgct ttaacttccc ctgcagcaaa ggtaatcggc accataatct taacagatgt
    12541 cgctgccaaa ccagcaatta cggttacacc gataatattg gcaatacgag aaatcgttgc
    12601 catctgctcg cttagtttat caatcacagt tgttcctagt ttgtatccat acagaccagt
    12661 tgacaattta atcgctgtta aaatcgtatt catcgcaagg aagaacaaga ttggaccgac
    12721 aaccaagcct tcttgagcaa acgaagctgc gatggttgag aacaatggag ctaaacagaa
    12781 ttgagaaaga gaatccccaa tacctgccaa tggtcccatc aaggccatct tgatgctacg
    12841 tgtttctttt gttggtcgac cattttccaa cattacaaga tgcaagctgg taataaaagg
    12901 caggaagtgt gggttggtat tatagaattc acagttttct tccaaggctt ggtagaaacc
    12961 ttcctgatcc tctccatagt gttttttcaa agcaggatac atcacattgg catatcccaa
    13021 cccttgatag ttactatagt taaatccatt ttgacaaaag aatgcccgca aagacgtttt
    13081 aagataatca cgttttgtta atttgttaga tccagtcatc gtgtgcttcc tcctctacca
    13141 catgatccgc tgtttttggc ttgttataaa attcaatcaa agcaaagata gtacctacaa
    13201 ttgcaatacc aattgttggg atgtttagat aagctgcaca aacatatccc aacaagacaa
    13261 agggaatcaa ctctttctta gccatcactg acaagatcat cgcaaaaccg atagctggga
    13321 gcattttacc agcaactgtc aaacctgtaa gtaataccgg tggaatgtag tctacgagtt
    13381 tcaacaaggt atccattgaa agggcaccca agcaacccaa ggtaaatcca ataaaggcaa
    13441 acaaccaaat tgttgcattt agagtgaact tgaatttctt caaattatgg tttttcaagt
    13501 gcttcatcgc cgtttcaggc gcaccagcac gtacagtgta ggcgaaagtt tgtaagaatt
    13561 gaatcgccac agcaatcgga gtagagaggg caagagccgc ttctggactg actttaccag
    13621 cactagtgat agccatcaag gtaccaaaga taccaggtcc gattgggttt ggtggaacag
    13681 tacctccagc accaacaccg aatcccatat aagccaattc accaatagct cccattgcaa
    13741 gagcagtagg cagatcacct agaataattc cgacaccaaa tgacagaaca atacatctat
    13801 tggtgtaaat tcctaacagc attccactaa aacagaaagc tgtccataat ccaattaaaa
    13861 tcgcttgaaa tacattaatc gacataacga tctcctcttt taaatatagt ccataatgtt
    13921 gacttgaaca gctccatcat ttcctgttgg agttgttttc gtattaaatg ttacttgatg
    13981 agtttggctt aattccttga gggctgcctt gtcctcttca cccaggaaga tggagcgtgt
    14041 cacttgctct ttaccagggg cattgtgaat gttcccaata ttgatttctt tgatagggac
    14101 accaccttct accaaggtta aagcgtcctt tacatccttt acaacgataa agatcgtttg
    14161 agcaggatta gccttgtgaa tgatatcaat caccttttgc aaagggaaga aacgcatggc
    14221 aactgagtct ggcacaactg ttttcatcag agtttgttgc atcttgtccg tgcttacttc
    14281 gtcattggca acaatgaccg tattacaacc taggtatttt acccaaagtt gtccttgtcc
    14341 atgaatcaac cgttcatcga tacgggtcat aataatattt ggcattgtca tatttctcct
    14401 cctaccaata taggttccag tctttgtaga aacggataag ggcttctagg taatagtagt
    14461 caccccagat attgccttca tccactcctt tacctgaatg ccatgagtac acaccgtgga
    14521 ggagacttgt cccaccaggg gtaaattgat catttgcata atgttcgatc aaggaacgaa
    14581 gcatggcatg catagcatgt ttataaatat ctttgtcagc atccacctct gggagatgtt
    14641 ttagcatttc atgaatccca cagacggcga tagctgttgc tgaagaatct cgtgattgat
    14701 cactaccatc attaaaaatc aaatcccaat aggacacatg atcttttggc agacgattca
    14761 agaaataatt ggtcacaccc ttaaacaagt caaagcagga ctcgtctttt aagtgacgat
    14821 aagtcaaagg aataccatag actccccatg attgaccacg tgcccagcat gaatcatcac
    14881 tatacccttg tctcgttaca cctttaaagg gttgacctgt ctcaggatca aaatagaagg
    14941 tgtggaagga cgaagcgtca tcacggatta cattattagc tgaagcatag aaatggcttt
    15001 ctgcaatatc gtagtatttt tgatcgcctg tttcttgata agcaaagaat aagagttgga
    15061 tattgagcaa gcagtcgata atcaaacggt aatgctcttt cttgcccaag tctccccaag
    15121 cttgaataaa accacctttt tcttgatagc gttcaatcaa cttatctgca gctttcaagg
    15181 ttgcttctct agtctctcca tctccattta tcttatattc agccatacaa gacggtgtgt
    15241 acaagaagcc gagatcatga tgatccaatt ctactctctt attgacacga tccaggaaag
    15301 aaagaacatt tttatgagcg atgtttttaa atgcatcctg ttgactgtat tcataagcca
    15361 accacagttc tcctgtccag aaaccattgg tccattccgt gttatccatg attggataga
    15421 cattatcaaa ggtagctggc gtcgggaaat cttccttgaa atagtcaagg ttgagttcta
    15481 actgccgaat aaccttatcg attgcctggc cgacttcttc tttcgtcaga agtggtactt
    15541 ctaagaagcg ctcaggcgac tttatttttt caatcgtaac cttttttatc attctttcac
    15601 cctttaaata cccgattcga aatcttcttc ctcttcctct gcatccgttg aaaacaattc
    15661 tttaccattt acgactccgc cctgggccgc cactactgat ttattaacaa cctcatcaaa
    15721 gctatgagcc attctagcaa agactgcttc cattaacatg gctaagttca aacccgagag
    15781 aacattcatt gttttggctg gattttctcc cattatggta gaagaaacct tgaatggcga
    15841 tcctcccaag agatcactta ggattaaaac ttcttcttca tttgaaattg caagtaagat
    15901 tttttgcttg agttcatctg ctgacattcc ttccacaaag tcaatcgcct ccacattttc
    15961 ttgattgcct gcaatcaatt gtaaagaact ataaatccct gtagcaaaat gtccatgccc
    16021 tacaagtaca attttcatct tttctccttt cttgtttagg tttaccggtt tactttatat
    16081 tccccattgt aatcctttat ttttatcttg tcaatagttt ttttaaaaa
//
LOCUS       DBEJNA010000044        13329 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEJNA010000044 DBEJNA010000000
VERSION     DBEJNA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.44"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            143..490
                     /locus_tag="ACL3JB_001787"
     CDS             143..490
                     /locus_tag="ACL3JB_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0686470.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(769..1605)
                     /locus_tag="ACL3JB_001788"
     CDS             complement(769..1605)
                     /locus_tag="ACL3JB_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0686471.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(1618..2247)
                     /locus_tag="ACL3JB_001789"
     CDS             complement(1618..2247)
                     /locus_tag="ACL3JB_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0686472.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(2257..2898)
                     /locus_tag="ACL3JB_001790"
     CDS             complement(2257..2898)
                     /locus_tag="ACL3JB_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0686473.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(3044..4273)
                     /locus_tag="ACL3JB_001791"
     CDS             complement(3044..4273)
                     /locus_tag="ACL3JB_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0686474.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(4263..5429)
                     /locus_tag="ACL3JB_001792"
     CDS             complement(4263..5429)
                     /locus_tag="ACL3JB_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0686475.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            5573..6586
                     /locus_tag="ACL3JB_001793"
     CDS             5573..6586
                     /locus_tag="ACL3JB_001793"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0686476.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNNTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(6631..7050)
                     /locus_tag="ACL3JB_001794"
     CDS             complement(6631..7050)
                     /locus_tag="ACL3JB_001794"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0686477.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(7061..8467)
                     /gene="atpD"
                     /locus_tag="ACL3JB_001795"
     CDS             complement(7061..8467)
                     /gene="atpD"
                     /locus_tag="ACL3JB_001795"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0686478.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(8553..9431)
                     /locus_tag="ACL3JB_001796"
     CDS             complement(8553..9431)
                     /locus_tag="ACL3JB_001796"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0686479.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(9447..10952)
                     /gene="atpA"
                     /locus_tag="ACL3JB_001797"
     CDS             complement(9447..10952)
                     /gene="atpA"
                     /locus_tag="ACL3JB_001797"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0686480.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10967..11503)
                     /locus_tag="ACL3JB_001798"
     CDS             complement(10967..11503)
                     /locus_tag="ACL3JB_001798"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0686481.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(11503..11997)
                     /gene="atpF"
                     /locus_tag="ACL3JB_001799"
     CDS             complement(11503..11997)
                     /gene="atpF"
                     /locus_tag="ACL3JB_001799"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0686482.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(12011..12727)
                     /gene="atpB"
                     /locus_tag="ACL3JB_001800"
     CDS             complement(12011..12727)
                     /gene="atpB"
                     /locus_tag="ACL3JB_001800"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0686483.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12762..12962)
                     /locus_tag="ACL3JB_001801"
     CDS             complement(12762..12962)
                     /locus_tag="ACL3JB_001801"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0686484.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(13037..>13329)
                     /locus_tag="ACL3JB_001802"
     CDS             complement(13037..>13329)
                     /locus_tag="ACL3JB_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0686485.1"
                     /translation="EFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTK
                     KMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         4102 a         2953 c         2372 g         3902 t
ORIGIN      
        1 atctataagg gatttaccca ctacaaatat tatagagcct aaaagatgag accaaccaac
       61 ctcatctttt ttcgtatcaa atctaagcaa ttttagaaac tttatggcat actagactta
      121 tcaatgaaag cgaggtaatc tcatggaaca atttttagat aacatcaaag accttgaagt
      181 cactacagtt gtgcgtgcgc aagaagctct tgataaaaaa gaaactgcaa ccttctttat
      241 cggtcgcaaa acttgccctt actgccgtaa atttgcaggt acattgtcag gtgtcgtagc
      301 tgaaaccaaa gctcacattt acttcatcaa tagtgaagaa ccaagccaac tcaatgattt
      361 gcaagcattc cgctcacgct atggaatccc aactgtacca ggttttattc atattacaga
      421 tggacaaatc aacgtccgtt gcgactcttc aatgtcagca caagaaatca aagatttcgc
      481 aggattgtaa aaaatcagct aacaagtctt aaaatcacaa aaacgcataa tgtaaggtgc
      541 aaaaaccttg atattatgcg ttttattgtt cctaaaacag ttacatcagc atttcattac
      601 agaacatttt aattttggaa gtcaaatcaa tttttaacaa tattttagaa atcacagtgg
      661 gctattccat attcaattat ccagattcaa tcgctattat cgttttccta gattacaaaa
      721 aaaactacgt tttgctaatc aaaacgtagt ctcagccact attttatctt actgtccttc
      781 ttttacttct ttggttgcta catcttctcc aaaccatttt tggctgattt cttggaactt
      841 gccgtccttg taaagactag aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc
      901 cttacgggct ccaaccgcaa aagcttctgt ttctagtcca actgtaaaga cattataatc
      961 gtttaaaaca ccttctgctt ctaaataata gtttgcatag acacggtcaa tcaatagacc
     1021 atcaattcga tcgtttttca aatcaatcaa ggcttcatta aaggtttggt attgattcgc
     1081 ttccttatta gcgacaatat tcttcaaaag ttctggattt gcttcaaagt ccgcataacc
     1141 agatgaacca gcttgagctc ctaatgtctt tccagtcata tcctttgcag tcgtgatacc
     1201 agatgatttc ttcgtaacca atacctgctc attcttcata tatgagttac tgaaagccac
     1261 cttttcacgg cgttcgtctg tagcggaata gccattccaa atcagatcaa tcgttccttt
     1321 tgtcaattca gcttctttca aatcccaatc aatcggttgc caatttaccg tgattccgta
     1381 tttttcaaaa acagctgtag ctaaatcaat atcaaatcct gcataagaac catctttctg
     1441 agcaaatccc attggaacaa aagtactatc aaatccaata gtaatagact tgttagactg
     1501 gtactttgac caattatctc cactagtttc gctagaattt ttcccacaag ctactaagaa
     1561 caaagcagtc atcagactga ctaatacaag catccatttt ttcatccatt tttcctccta
     1621 tttaggttct actttcaata atacatctgc gatattttca gcaaactgca aatcatgggt
     1681 aaccacaatc tgggtcatcc caagttccct attttgcaag attagcttct ccacttccaa
     1741 acgtaattct ggatccaggg cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat
     1801 catcatagca cgcgccaaag ccactcgctg cttttgccca ccagatagtg agaaaggata
     1861 ggcctctgcg tgtcctccta gtcctaactg ttccaagagt ccactcgcct tcttctcagc
     1921 ctcttcctgc ttcattccca tggtcttcac aggcgataaa gtcaaatttt ccagaactga
     1981 tagatgagga aatagttgaa aatcttggaa gacaaatccc agtaggttgc gcttctgcaa
     2041 ttcatccagc tctaaaggtt gtccattata aaagatttgc cctgaatcaa tggtttcaag
     2101 acctgcaagc atacgtaaaa gagttgtctt acctccacca gaaggtccaa cgatagccag
     2161 gatttgcttt tcaggaatac ttagactgaa attagacagg atttgtttgt ctccaaagac
     2221 tttattgata tttcgtaatt ctaacatggc agcctcctat ctataataac tatacttctt
     2281 ctcaactttt ttggaaataa ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc
     2341 caagaacata ggaactagac tagcatcgcg gttagcagct gttcgactag ccaagataag
     2401 gtctgaaatt ccgagagcat agaccaaaga agtatccttg accaaactca taacttcatt
     2461 aaagacacta ggaagaacaa tcttggtcac ttggggcaag ataatatagc gcactctgtc
     2521 aaaagggcta aactttaaga ccttggcagc ctcatactgt cctcttggaa tagtgtcaat
     2581 tcccccacgg aaaatttctg caaagtaagc tgcatagttg agaacaaagg caataatagc
     2641 tgcaggaagg cggtctaaac gaatcccaat acttgggagc acataataga taaaaatcag
     2701 ttgcaagagt aagggggttc ctcgcataac ccagatgtaa atgttaatca gataatggag
     2761 gggcttccaa tggacttgca aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag
     2821 caagaccagt gcaaagacct gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat
     2881 ctcaaataaa taagacatac tgcacctcct aaaagtaatt gttcctatta tagcatgaat
     2941 aaacaagatt accaagtatt tttgtaaaaa gattctacca tatacaaata aaaaccgtag
     3001 ctatcaaaag agataaacta cagttctata tgtttaaaca ttcttacaat ctctcaaaca
     3061 gttcttgcat ttgcacatca tctggaacca gttttaagta agtgtgagca tggacttttg
     3121 cttcttcaaa atgtcccaat tcacgcaaga gatagatata gtgttccaga aattctggat
     3181 tgtccttcaa atctcctgtc aactcttgat aatgctcata agcagtatcc aaatcgtcca
     3241 tttcttgata agaacgagca atcatccact tggtcaaaag attttctggc tcctcactct
     3301 gcaagtctag aatatcctca taacgctcct gctccagata aatagtggct aaacgaagca
     3361 agatttcttc tgtatcctca gcgtcttctt ttgcagtaag gagataattt tctgcaccac
     3421 tagcatcatg caattcataa gaaaattgtg aagcagctag caagaggcga gtttcaaagg
     3481 gatttttctc taatccttgc ttagcgatac gcagggcttc ttgaacttga tgttccttat
     3541 gtaaagcctg actgtaccca tactcatagc cttcaaagtc aggagaaatg gtatcaagct
     3601 gcttaaagta gagggtggct ttttgatatt cttcttgatc aaaataaaga ctggccaact
     3661 caaaagctgt taagtcatcg tattctaact ccagggcttt ttctaaaaac tcagtagccg
     3721 tttcaaattt ccctaactga gcataggcaa agccaattcg ttgataggtg gaaatgcccg
     3781 tttgctcata aatcgagcga ttatctaact gggcataggc ttgaatagcc gcttggtaat
     3841 tttccaactc actatccaac tctgccaaac ccaatatcaa gagagaatcc tctgagtagg
     3901 tcaaggcctc caataatttc tcacgtgcca catctgtcaa accttccagc tggtaaaggt
     3961 ctgccttcaa aaccaaagac gagacatacc agtcactgtc agcttggatt tcctcaagat
     4021 aggtaaaggc ttcttctatt tgaccatcct cgctagcaat tgcagctaga ttaagatgaa
     4081 cctctggaaa atcctctaca attttcaggt aaatttcctt ggcctgagga tagaaaccaa
     4141 tcccttcaag ataagttgcc aactcataca gaagattact tgaatcattt tctaaagctt
     4201 tggcgaaata atgctcagcc ttagttaaat cttgctcctc caaagcctgt aacatctgtt
     4261 gactattgtt cactcttgac ttcctcaccc tctaattcat atagaccact gactacctta
     4321 taccattcga aaatggctga aatgacaacc ttagcagagg cataaaccgg aataccaagt
     4381 aaaactcccc agataccaaa catagatcct gaagttaaca aaacaaagag aacattaata
     4441 gggtggatgt ttaattgact tcccaaaatc aatggagaga caaaacggcc ttcaatagtt
     4501 tgttctacga taaagacaat cactactttc aaaagcatga ctggaccagc aatcaaaccc
     4561 aatactagag caggaagcat ggctagaaag ctaccaagat aagggaccag atttaaaata
     4621 ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa taatcttgaa gaagatgata
     4681 aacattactg ctacaataat agccactgtc acttgccctc gaacatagtt ggacaactgt
     4741 tgattcacat ctgataaaac ttgtccaaca ggttccttca attttcttgg aatgaattgg
     4801 gtcaaatagt tacgcaagcc tttcccatca cgcaagagat aaaagagcat gaaaggaacg
     4861 ataatcaagg caacaatcac ttgagaagcc ccgctaataa aggcactcac ccagttgact
     4921 gcctgagatg aaaccttact tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact
     4981 tgctctaatt gaggtctgaa atcatctggc aggtgctggg ctaccaatcc attaacaatc
     5041 ctatctatat cttctaagta aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc
     5101 agatttggaa tggcgactgc caagccccaa atgataaaga gagcgatgat aacaaagaca
     5161 atagtgatag ctataacacg attaacctta tgcttctcca tccaatcaac aataggattc
     5221 aacaaataat ataacaaacc agacaaaatg actggcaaca tcacaactgc taaaaagtct
     5281 aaaacaggtg aaaatagaaa actaatctta cttaaaataa aaagattcag tcccaataat
     5341 aaggttacta aaaataccgt aattgccttg ttatctaaaa accacttgaa aaaccaagat
     5401 aggctaaaat gtttctcttt ttgctccata aatacttcct ttctattgtt ctctcattat
     5461 accatttttg aaacaaaata actctttttt aaagtgctta catctaattg gatatcttta
     5521 atttacttgt ttttgtgata taatagtctt atctttacac agaggtatag taatgaaaga
     5581 aactgtttat tttggaactt atacacgtcg tacttctcaa gggatttaca aggcagactt
     5641 tgatacagaa actggtcagc tttcaaatct agaacttttt gcagctgagc caagtccaac
     5701 ctaccttgcc tttgaccagc accaacattt atacactgtt ggtagccaag acgataaggg
     5761 gggaattgca gcctatcaaa ctgacgggac tgtgttaaat catgttgttg aagaaggagc
     5821 tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg gtttacgcag ctaactatca
     5881 caagggacaa gtccttgttt ataaacgcca ggaagatggt agtcttctac ttagtgatat
     5941 ggatcaacac agtggccaag gtccacatga aaatcaagct tccccccatg ttcactatac
     6001 agatttaaca cctgaccact atctagtgac ctgcgacttg ggaactgacc aagtcatcac
     6061 ctatgacctc gatcaagaag gaaaattatc taagctctat acctatcaca gcaagccagg
     6121 agcaggctca cgccatatca ttttccataa ccactataaa atcgcttatc tcatttgtga
     6181 actcaataat actatcgaag ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca
     6241 ggtcatttca actttaccgg aagcttacga aggctttaat ggaaccgctg ctattcatct
     6301 ctctaaagac ggtaaatacc tctacgcttc taaccgtggc catgattcta tcgcagtata
     6361 taccatcctt gcggacggta gcttagagtt attagaaatc gttccaacgc atggtcagac
     6421 tccacgtgat tttgatttga cacccgacca aaaatttctc attgttgtcc atcaagactc
     6481 tgacaatgca actgtcttta aacgtaattg tgacaatggt cgtctagcag aactctccaa
     6541 cgacttccat gttcccgaag cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa
     6601 tgaacttggt attttcaagt tcattttttc ttatagtcta tttccgacat taatacggtt
     6661 aatggcacgt tgcaaagcaa tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg
     6721 tgcttcttca attgcacgtt ctgcacgaag tttggcacgt tctgcacgac tgatatcgat
     6781 atcacgagca cgttctgcag agtcagcgac gattgtgatc atatcattgg caatttcaat
     6841 aacgccaccg tttactgcaa tccagttcac gtgatcttta tcatcgatac gttttacctt
     6901 tacttcatca actgctaaaa ccgcaatcat attttcatgt cgtggcaaga tccccatctc
     6961 accatccaga gttcgaaccg atacatagct ggcatggtga tcatagacga gaccatctgg
     7021 tgtcacgatc tggacagtta actgagccat agatcacctc ttaaaatccc attttttcag
     7081 cttttgcaat cacatcttcg atagaaccta caccacggaa ggcatcttct ggcaagtggt
     7141 cgtatttacc atcaaggatt tccttaaagc cacgtacagt ttcagcaact ggaacataag
     7201 aacctggctg accagtaaat tgttccgcaa cgttgaagtt ttgtgacaag aagaactgga
     7261 tacgacgggc gcgagcaacc aaggtctttt cttcatcaga aagctcatcc ataccaagga
     7321 tagcaatgat atcttgcaat tcatggtaac gttgaaggac acgttttact tcagcagcaa
     7381 ctgcatagtg ctcttctcca acgatttcag gtgccaaggc acgtgagctt gaagcaagtg
     7441 ggtcaacggc tgggtagata cccaattgta ccaacttacg ttccaagttt gttgttgaat
     7501 ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata gtcatccgct ggcacataga
     7561 tagcctggat agaggttaca gaacccttct tggttgatgt gatacgttct tgcaattgac
     7621 ccatttccgt agcaagtgtt ggttggtaac caacggctga tggcatacga cccaaaaggg
     7681 cagatacttc tgaaccagcc tgagtgaaac ggaagatatt atcgataaag agaagcacgt
     7741 cttggccttc cacatcacgg aagtattcag cgattgtcaa accagtaagg gcaacacgca
     7801 tacgtgctcc tggtggctca ttcatctgac caaagaccat ggctgttttc tcgataacgc
     7861 ctgattcttt catttcccag taaaggtcat tcccctcacg agtacgttcc ccaacaccag
     7921 taaatactga aataccaccg tgctcttggg caatgttgtg aatcaattct tggattaaga
     7981 cggttttacc aactccggca ccaccgaaaa gtccaacttt accaccttta aggtaagggg
     8041 caagaaggtc aataaccttg atccctgttt caaggatttc agaagaggta gacaactcat
     8101 caaaagttgg agctttttta tgaattggct gacgctctgc gtcttctgta aaaggagctt
     8161 ccaaatcaat ggtatctccc aaaacgttga agacacgtcc caaagtttct ttacctactg
     8221 gtacagagat tggacgacct gtgtccaata cttccattcc acgagtcaac ccatctgttg
     8281 attccatggc gatagtacga accataccat ctcctaactc caaggctact tcaaggacga
     8341 tttttgtttt tctttcgtca tttttgtaga cgacaagtgc attgttaatc tcaggaagtt
     8401 tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat aacctgagca attttacctg
     8461 aactcatctc cttctcctat tctatataag atactgtcgg ttcctagctc aactaggtcc
     8521 taagttcatt ttcatacgag ctggactaga gcctattcta aggcactagc acctgctacg
     8581 atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac ggttatactg aattgtcaaa
     8641 tcattgatga ctttcttagc attatctgtc gctgtttgca tggctgtcat acccgcagca
     8701 ttctcagctg tcttggcatc gataatggca ccgtaaatca tactttctgc aaactgaggc
     8761 aacaactgct ccagaatttc ttctcggctg gtttccaatt caaaagtcaa gctgtactct
     8821 tcatccgctt catttggatc caagtcaaca atcggaagca tttgttccac acgcatttga
     8881 ctggttagcg tattgacatg gtggttgtag caaacataaa gctcatcaaa gagttcattt
     8941 tggtacattt caacagtttt tgaaataatc ttacgaactt gatcaaagct aggttggtct
     9001 gccaagccac gtaattcata aagtggttga ataccgcgag ccttaaagaa atcagctccc
     9061 atcccaccga tacagatcat ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac
     9121 tccataacag ctttcaaaat agaggaatta taacctccaa ccaaaccgcg gtctgaagtg
     9181 ataacgatat agcctgtctt cttcacagaa cggctaatca acatcggatt agttgaagca
     9241 ccagctccat taccatgaag gatatctgtc aaaagtttac gcactttctg agcgtaaact
     9301 tggaagttgc gagcagcttc ttcagaacga cctagcttag cagccgatac catttgcatg
     9361 gcattagtga tttgactcgt attttttgtt gaggcgattt ttgttttaat atcatttaga
     9421 gatactgcca tctgacacct ctattcttat tggaagctag attgattgag aaactctgta
     9481 atcgcagcat ccaagactgc ttcttctggc aagtcttttg tatcacgaat ggtttccaaa
     9541 atctctggat gttgagcatc aaagaaggta tggaactctt cctcgaaacg aacaatatca
     9601 tctactggaa cagtatccaa gaaaccatgt gtcaaagcat aaagaatggt tacttgtttc
     9661 tcaacaggta atggtttgtg aacaggttgt ttcaagacct caacggtacg acgtccacgg
     9721 ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac
     9781 tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa ccttcttcat ggctttgatt
     9841 tgtgcagaac cacctacacg agatacagat gaacccgcat cgatggctgg acgaatacct
     9901 gcattgaaga ggccatcgcc aaggaagatt tgtccatcag tgatagaaat cacgttggtt
     9961 gcgatatagg ctgagatatc tcctgcttgt gtctcgataa atggtagggc tgtaattgat
    10021 ccaccaccaa gttcatcaga aactttagct gagcgctcaa gcaaacggct gtggagatag
    10081 aaaacatccc ctgggaaggc ttcacgacct ggaggacgac gaagcaagag cgacagttca
    10141 cgataagcta ccgcttgttt tgatagatca tcgtatacaa tcaaaacatg cttaccttga
    10201 tacataaatt cttccgccat agcaacccca gcataaggag ctaggaagag caatggagat
    10261 ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt
    10321 gtttctactt gcgtacgaac tgttgattct ttttgtccaa tcgcgacgta gatacagatc
    10381 atatcttgat ctttttggtt caagattgta tcaatcgcaa tggttgtttt ccctgtctga
    10441 cggtcaccga taatcaactc acgttgacca cgaccaatcg gtacaagggc gtcaatagct
    10501 ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt gcataacacc aggagctggt
    10561 gcttctactg gacgagtttt atcagtgtgg atttctccaa gaccgtcaac tggacgacca
    10621 agcggatcca caacacgacc aatcagactt tcacctacag ggacttccat gattttccct
    10681 gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt cacctaggat gataatacca
    10741 acgtctgttg actccaagtt ttgagccata ccataagagc cgttttcaaa attcaacaac
    10801 tctccactca tgacattttc aaggccgtga gcacgcgcga taccgtcccc gatataggtt
    10861 acaacacctg tttcagtcac atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt
    10921 aaagcgctga tttcttgtgc gttaattgcc aaaagaacac cactttctat ttcaaatttt
    10981 ctttaacaac tttaagttgt tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa
    11041 tgacaaaacc accaatgaga ctttcatcga tttgttcttt tacactcctt actttcagag
    11101 acattttttt ctcaatcaaa gggagcaaac gagtcttctg ttcatcagtt agaggatgag
    11161 cagacgtaat cgtcacttca aatcgatttg tttctttttc aagtcggttc aagcaatcta
    11221 caagcacatc ataaaaaaga tttgctctat gattgtaggc cagaacctgg ataaagtttt
    11281 gtaataaagg tgacacagaa tcttggaaaa aagcaattgt tttttcctta tccgactcgt
    11341 ctactgccac ttgctttaaa aaagaaggca gacctgtttt ttcaacaact tgcttgattt
    11401 gagtcaagtc tgaaaagata cggtcttctt ctcctttttc aagtaccaat tggacaaaag
    11461 gcatgctata tttttcaatt acctttactg ttttcttgtc cattaagctt ctcctagctg
    11521 atcgatatac tgatcaatga gtgctttatg ggcatgactg tcaaggtttt gtgagatgat
    11581 tttaccagct aagctgatgg tcaaatctgc gacctcaccc ttaacactct gtaaagcttc
    11641 tactttattt tgagcaattt cttgattggc tttttctttt aagtgtcctg cttctagttt
    11701 agcatctgct aagatattag ccttactttg ctcagctgtt tcctttgcat tttcaatgat
    11761 tgtcttagct tctttacggc taccagccaa ttcatcttcg cgtttttgag ccaatacttc
    11821 tgctttttga cgggcttctt cagctctgtc aatatctgaa gcaatttttt cagctctttc
    11881 ttcgaaaatg cctgtaatat tagaccatgc aaatttttta atcaagacta gcaaaagaat
    11941 aaaagagcca gtgattaaaa taaaattacc aattaattca cctactgtta cgtgcatcag
    12001 ttactccttt ctattcctct tcaatattaa tcttattccc taaatacaca gatgtcaaaa
    12061 gagtaaaaac ataagcttgg atgcaggaaa taaagacaga aaatgcagtc caagccaaat
    12121 tagctccaaa ggctactgga taccaataaa tagcttggtg ggaaagaaga agtaacaaac
    12181 tcgtcatgac ctctcctgca aagatattcc caaaaatccg caaagccaaa gataagaagt
    12241 ttgtaaattc ttccaagata ttcatcggta tgacaaaaac aggactcata aaagatttta
    12301 tacttttttt aaatccacga cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa
    12361 aagataaggt taagtcatac tgtaaattag cggttggcga actccaccag ttagtcccat
    12421 cgatcgtttg aagctttgtc attaagccaa ggttattggc aatcaccatg aaaaggaata
    12481 aacaaaggaa aaagagtgag taatctttca tgtagcgcga accaatgtta ggttctgtaa
    12541 atccaataac aaagtcatag acatactcaa gtacattttg ctttcctttg ggtttcaagg
    12601 tcatattgcg gcttgcccaa taaataaaga caaaaataac tcccacaatc aacaaagtca
    12661 tggctaacat agtcagattg aagataacag gaccaataga gatgattgga ttaatacttt
    12721 cttccatcta aaatcctccc ttttcttctc gttccatgta tttatttgat aataaatgag
    12781 aagacaagag ttacaaagaa agttccttca ataaaggcaa cacctaaaaa catcaaacta
    12841 cgaaactcag aaagcatatc tggttggcgt gctactgatt taaacagtcc attcatcaat
    12901 aaaccttcac cgacagatac gcccatacag gcaatacata agcctaaaaa tgttaaattc
    12961 ataacaaatt ctcctttaaa ataaaattta cttacttagt gtagtcctaa aatttaaatt
    13021 tgtcaacttt taaccgctat tggaagcgtt taataaaaat tatttccatt ttgctaaatt
    13081 tcaagttcaa gttagccatc cagaagtctt ctctgggtga cttgtagtcc aagcattttt
    13141 taggatagtt gttaatccac ttttcgatga atgcgacttc tttgggagtc attttcttgg
    13201 ttcccttagg taaccatcta cgaatgagcc tgttatgatt ctcattagtt cccctttccc
    13261 aagaggcata ggggtgcgca taatagatgt gctcctcaga aaatacatca aacaagcgat
    13321 tgaattccg
//
LOCUS       DBEJNA010000045        13313 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEJNA010000045 DBEJNA010000000
VERSION     DBEJNA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.45"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..343
                     /locus_tag="ACL3JB_001803"
     CDS             <1..343
                     /locus_tag="ACL3JB_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0686486.1"
                     /translation="ITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLE
                     KPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPE
                     ALYAYIAEATA"
     gene            381..682
                     /locus_tag="ACL3JB_001804"
                     /pseudo
     CDS             381..682
                     /locus_tag="ACL3JB_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
     gene            690..1493
                     /locus_tag="ACL3JB_001805"
                     /pseudo
     CDS             690..1493
                     /locus_tag="ACL3JB_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1684..3975
                     /gene="pcrA"
                     /locus_tag="ACL3JB_001806"
     CDS             1684..3975
                     /gene="pcrA"
                     /locus_tag="ACL3JB_001806"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0686487.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            4018..4698
                     /gene="radC"
                     /locus_tag="ACL3JB_001807"
     CDS             4018..4698
                     /gene="radC"
                     /locus_tag="ACL3JB_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0686488.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(4695..5384)
                     /locus_tag="ACL3JB_001808"
     CDS             complement(4695..5384)
                     /locus_tag="ACL3JB_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0686489.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(5402..6043)
                     /locus_tag="ACL3JB_001809"
     CDS             complement(5402..6043)
                     /locus_tag="ACL3JB_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0686490.1"
                     /translation="MKYKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(6126..6341)
                     /locus_tag="ACL3JB_001810"
     CDS             complement(6126..6341)
                     /locus_tag="ACL3JB_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0686491.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(6349..6696)
                     /locus_tag="ACL3JB_001811"
     CDS             complement(6349..6696)
                     /locus_tag="ACL3JB_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0686492.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(6701..7816)
                     /locus_tag="ACL3JB_001812"
     CDS             complement(6701..7816)
                     /locus_tag="ACL3JB_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0686493.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(7826..8785)
                     /locus_tag="ACL3JB_001813"
     CDS             complement(7826..8785)
                     /locus_tag="ACL3JB_001813"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0686494.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(8898..9467)
                     /locus_tag="ACL3JB_001814"
     CDS             complement(8898..9467)
                     /locus_tag="ACL3JB_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0686495.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            9595..10266
                     /locus_tag="ACL3JB_001815"
     CDS             9595..10266
                     /locus_tag="ACL3JB_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0686496.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10250..11068
                     /locus_tag="ACL3JB_001816"
     CDS             10250..11068
                     /locus_tag="ACL3JB_001816"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0686497.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            11065..11961
                     /locus_tag="ACL3JB_001817"
     CDS             11065..11961
                     /locus_tag="ACL3JB_001817"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0686498.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            12005..12979
                     /gene="pta"
                     /locus_tag="ACL3JB_001818"
     CDS             12005..12979
                     /gene="pta"
                     /locus_tag="ACL3JB_001818"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0686499.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(13079..>13313)
                     /locus_tag="ACL3JB_001819"
     CDS             complement(13079..>13313)
                     /locus_tag="ACL3JB_001819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686500.1"
                     /translation="LQKTDFYRFEHQKRKDKICPFSSLADFNPLQLTKSQKILFSYSF
                     KIKKGIYRFTDMYITDFYRSCIDRISSLGSFPF"
BASE COUNT         3944 a         2535 c         2843 g         3991 t
ORIGIN      
        1 gatcacgcgt gaaaagtcat ttccaactgg tttagatatg gaatttctag gaaaggactt
       61 gccaaatgta gcgattcctc acacagatat tgttcataat ctagctgaaa aagtggtggt
      121 tgttcgatta gaaaaaccag taacttttca caatatgata gctcctgata aggaagtaga
      181 agtatcccta ctcttcttta tcattaacaa ttcaagttca agtcaaacaa atattctggc
      241 tcagttgatg gactttttca caggaaatgg acatcttgaa gatttatcaa aaatttctga
      301 accagaagcc ctttatgctt acattgctga agcaaccgct taatcttgtc tattaaaaaa
      361 taaaatcgga ggaaatccaa atgattaaaa ttcttgctgc ctgcggtgag gtgttaactc
      421 gagttaccaa attaaaagtg ctctagaaga agaactttca aaccgtggtt atgatgttca
      481 ctgtgatgca gtcatggtga aagatgtaaa cgaagacctt atgaaaggtt acgatatctt
      541 tacaccaatc gctgcaacag atcttggttt tgaaccaggt atcccagtta tcgaagctgg
      601 gccaatctta ttccgtatac cagcaatgag cgctccagta tttgacaata ttagactccc
      661 tgcgaaacaa aacatggtat agtagttcta tgaatgatga agcaagtaaa caactaactg
      721 atgcacgatt taagcgtttt gttggtgttc agcgcacgac ttttgaagag atgttagctg
      781 tattaaaaac agcttatcaa cttaaacacg caaaaggtgg acgaaaacct aaattaagcc
      841 tagaagacct tcttatgccc actcttcaat agtgcgagaa tatcgaactt atgaagaaat
      901 tgcggctgat tttggtattc acgaaagcaa ctttatccgt cggagccaat gggttgaaat
      961 aactcttgtt caaagtggtt ttacggtttc aagaactcct ctcagttctg aggacacggt
     1021 aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaacaatta gcgaatgatt
     1081 ctggtaaaaa gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa
     1141 ttgtttcttt ggatatcgct gtgaactata gtcatgatat gaagttgttc aaaatgagtc
     1201 gtagaaatat cgaacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga
     1261 agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg
     1321 aagataaagc ctataaccat gcgctatcta aggaaagaag caaggttgag aacatctttg
     1381 ccaaagtaaa aacgtttaaa atattttcaa caacctatcg aaatcatcgt aaacgcttcg
     1441 gattacgaat gaatttgagt gctggtatta tcaatcatga actaggattc tagttttgca
     1501 ggaagtctat tgaggtattg agctagttta tgaaaaaatt gggtgaaaag tcgagtgttt
     1561 tagaaaccca cagtgtagta ttctagtttc aatccactat attttgctac tccccgtaaa
     1621 gtttctattt tccctgattt ctgatataat agaaatattg acttcaagag taaggaagag
     1681 aagatgaacg cattattaaa tggaatgaat gaccgtcagg ctgaggcggt gcaaacgaca
     1741 gaaggtccct tgctaatcat ggcaggggct ggttctggaa agactcgtgt tttgacccac
     1801 cgtatcgctt atttgattga tgaaaagctg gtcaatcctt ggaatatctt ggccattacc
     1861 tttaccaaca aggctgcgcg tgagatgaaa gagcgtgctt atagcctcaa tccagcgact
     1921 caggactgtc tgattgcgac cttccactcc atgtgtgtgc gtattttgcg tcgcgatgcg
     1981 gaccatattg gctacaatcg taattttaca attgtggatc ctggtgaaca gcgaacgctc
     2041 atgaaacgta ttctcaaaca gttgaacttg gaccctaaaa aatggaatga acgaactatt
     2101 ttggggacca tttccaatgc taagaatgat ttgattgatg atgttgctta tgctgcccaa
     2161 gctggcgata tgtatacgca aattgtggcc cagtgttata cagcctatca aaaagaactt
     2221 cgtcagtctg aatccgttga ctttgatgat ttgattatgc tgaccttgcg tctctttgat
     2281 caaaatcctg atgttttgac ctactaccag caaaaattcc aatacatcca cgttgatgag
     2341 taccaagata ccaaccacgc tcagtaccaa ttggtcaaac tcttggcttc ccgttttaaa
     2401 aatatctgtg tggttgggga tgcggaccag tctatctacg gttggcgtgg tgctgatatg
     2461 cagaatatct tggactttga aaaggattac cccaaagcca aggttgtttt gttggaggaa
     2521 aattaccgct caaccaaaac cattctccaa gcggccaacg aggttattaa aaataataaa
     2581 aatcgccgtc ctaaaaatct ctggactcaa aacgctgatg gggagcaaat cgtttactat
     2641 cgtgccgatg atgagctgga tgaggctgta tttgtagcca gaaccatcga tgaacttagt
     2701 cgcagtcaaa acttccttca taaggatttt gcagttctct atcggactaa tgcccagtcc
     2761 cgtacaattg aggaagccct gctcaagtct aacattcctt ataccatggt tggcggaacc
     2821 aaattctaca gccgtaagga aattcgcgat attattgctt atctcaacct tattgctaat
     2881 ttgagtgaca atattagttt tgagcgtatt atcaacgagc ctaaacgtgg aattggtcta
     2941 ggtacagttg agaaaatccg tgattttgca aatttgcaaa atatgtctat gctggatgct
     3001 tctgctaata ttatgttgtc tggtatcaag ggtaaggcag cccaatctat ctgggatttt
     3061 gccaatatga tgcttgattt gcgggagcag ctagaccact taagcattac agagttggtt
     3121 gagtccgtcc tagaaaaaac aggttatgtc gatattctta acgcccaagc gactctagaa
     3181 agcaaggcac gggttgaaaa tatcgaagag tttctttctg ttacgaagaa ctttgatgac
     3241 accacggatg tgacagaaga ggaaactggt ctggacaaac tgagtcgttt cttaaatgac
     3301 ttggctttga ttgccgacac agattcaggt agtcaggaga catcagaagt gaccttgatg
     3361 accctgcatg ctgccaaagg tctcgaattt ccagttgtct ttttgattgg gatggaagaa
     3421 aatgtctttc cacttagtcg tgcgactgaa gattcagatg aattagaaga agagcgccgt
     3481 ctagcctatg taggtatcac gcgtgcagag aaaattctct atctgaccaa tgccaactca
     3541 cgcttgcttt ttggtcgtac caattataac cgtccgactc gttttattaa cgaaatcagt
     3601 tcagacttgc ttgagtatca aggtctggct cgtcctgcaa atacaagctt taaggcatca
     3661 tatagcagtg gtagtatttc ctttggtcaa ggtatgagtt tggctcaggc tcttcaagac
     3721 cgtaaacgcg gtgctgcccc aaaatcaatc cagtcaagcg gtcttccatt tggtcaattt
     3781 acagctggcg caaaaccagc atctagcgag gcaaattggt ccattggtga tattgctctc
     3841 cacaagaaat ggggagaggg aaccgttctg gaagtttcag gtagcggtgc taggcaggaa
     3901 ttgaaaatca atttcccaga agtaggtttg aaaaaacttt tagccagtgt ggctccaatt
     3961 gagaaaaaaa tctaattttc catccttctc acgaataata aagtgaggag gatttttatg
     4021 tacagtattt cattccaaga agattcacta ttaccaagag aaaggctggc caaggaagga
     4081 gttgaagcgc ttagtaacca agagttgcta gctattttac tcaggacagg aacacgtcaa
     4141 gctagcgttt ttgaaattgc ccaaaaagtc ttgaacaatc tttcaagcct aacggatttg
     4201 aaaaaaatga ccctgcagga attgcagagt ttgtctggta ttgggcgtgt taaggccata
     4261 gaattacaag ctatgattga actggggcat cgtattcaca aacacgagac tcttgaaatg
     4321 gaaagtattc tcagcagtca aaagttggcc aagaagatgc agcaggaatt aggggataaa
     4381 aaacaagagc acctggtggc actctatctc aatactcaaa atcaaatcat ccatcagcag
     4441 accattttta tcgggtctgt aactcgtagt atcgctgaac cgcgagagat tcttcactat
     4501 gcaatcaagc atatggcgac ttctcttatc ttggtccaca atcatccttc aggagcggta
     4561 gcgcctagcc aaaatgatga tcatgtcact aaacttgtta aagaagcctg cgaattgatg
     4621 gggattgttc tcttggacca tttgattgtc tctcattcta attactttag ttatcgtgaa
     4681 aagacagatt taatctaaag ttcattaacg acatagtcaa agagtttttt atctttggga
     4741 cgattttcaa aaagaagttc tggatgccat tggacaccga gaaaggcgac atcatccgta
     4801 ctcatgacag cctcaatgat accatcttta ggatcatgag ccacaacttt taaatttggt
     4861 gctaagtcct tgatgctctg gtggtggaag gagttgatat gagagatttc tccatagatt
     4921 tcttggagaa cggtatctgg ttctgttacc aagcgttgag ttgtgtactc aacagaagaa
     4981 tcctgccaat ggtcttcgat atcttggtac aaagttccac ccatggcaac gttaaagagt
     5041 tgggtaccac ggcagacaga gaaaatgggc tttttctgtt taatagcttc cttgatgagg
     5101 gccagttcga agatatctct ttgaaggtga tagtcatcac tatcaatggt tttgggttcg
     5161 ccataaaatt ttggatcgac attttgccca cctgtcaaga tgagcttgtc aatcaaactg
     5221 atatagtggc aggccatttc ttgatcacca atcggtagga tgatgggaat ccctccagca
     5281 tctttaacgc cttcaacaaa gccttttgct gcgtagctca tcatgatgtc atcatctgga
     5341 tgagtttttt cgtttcctgt aatcccaata actggttttt tcataaaatg attttcgctt
     5401 tctaatcctc ttttcgcatg aagtagagga gggtttggag ttcacttgtc aaatcgacat
     5461 actgaacgac cacgtctttt ggtaaatgca gatggactgg tgaaaaactg agaattcctt
     5521 tcacaccagc atcaaccaag agattagcaa cctcttgtga cttgacgctg ggaacagtta
     5581 ggatagcagt cttcacatca gcatccttga ttttatcctt gatctgagaa atcccgtaaa
     5641 tgggaatccc gtcaggagtt tgggtaccga cttcaggatg gtcgtctagg tcaaaggcca
     5701 tgataatctt catcttgtta cgttcgtgga agcggtagtg gagaagggca tggcccatat
     5761 ttccaatacc aaccagcatg acattggtaa tagagttgtc attgagcaaa tcggcaaaaa
     5821 atgtcattag ttttttgaca tcatagccaa aaccacgacg accaagttca ccaaaatagg
     5881 aaaaatcacg acgtacggtc gctgaatcaa taccgatagc ctctgcaatt tgcttagagt
     5941 tggcacgttc aatcttttct gcatgaaatc tcttaaaaat tcgatagtag agagagagtc
     6001 tttttgctgt agcttttgga atagcaaact gtttatattt cacaaaatca caacctttct
     6061 attcttctat tttatagaaa cattgtgaaa aaatcaacaa aaataagaaa aaactaagaa
     6121 aaatcttagt tttgatgtaa aaaatctgca tgagatagaa aacggtagag gtctccgacc
     6181 agcccctgat aaactttttt gcccctaaaa gtcagagaag tcacataaag tgtatctggt
     6241 aaggttacac atcctgacaa agtcaacatg agagcctcat gatcctcata cttgagagta
     6301 cgctctacat gatagcagtc cttataggtc agttcaaaca ttttggctct atctttccga
     6361 ttttgtaaag acaccacgtt ctaccaagct atccatgagg aagtagaatt tttcctgatg
     6421 aatatggtgg tcttctgatt tgaaaatatc aactagacga aggccaaact tgtcagtgat
     6481 attgatttta gcccctgtaa gttccttgtt aatgatgatt ttgagttgga agccttcacc
     6541 gctgtttggc actttttcca aaaggcgagt cagttcatag ttaccaacct tagtttcaaa
     6601 aaaggtgtta tctttgaggg tgaatttttt aacagaaggg ctaagagtgt aatcgtaacg
     6661 acaatttttt aactgaatga ttttttcaaa tgccatatgg ctaacctccg ataatttctt
     6721 ttaaggtttt tgcgagggtt tgtaggtctt caacggtatt ttgtggcgac aaactgatgc
     6781 gaagggattc cttcaagcgt tctgaatttg cgccatacat ggctttaaga acatggctgg
     6841 attggacaac gcctgcagta caggctgagc cagtagagat tgaaattcca gctaaatcta
     6901 gccgaaggag taagaggtca tttttctgac caggaaatcc aatattgaga acataaggga
     6961 gatgatgttt tcctctattc aagtaatact gaatgccctc cagctctgcc agaaaggcag
     7021 tttctagatt ttgtacatgt tgaaaatgtt cttcttgttt ttctaggtct tcttttaggg
     7081 ctgcaaccat gcctacgatg gcaggcagat tttcagttcc tgcacgtttt ttctgttcct
     7141 gatctccgcc atgtagatag gaatcaaagt ccatgctaga tgcgtagaga aaaccgattc
     7201 ccttaggacc atggaatttg tgggcagaag cagtgagaaa atcaatgccc aattcttctg
     7261 aatgaattgg gattttacca atagcctgaa ctgcatcaac atgataggca gcagggtgtt
     7321 gcttgagtat ttggccaatt tcagcgatgg gaagtaggtt tcctgtctca ttattggcaa
     7381 acatagtaga aaccaaaatc gtatcgtcac gtaaagcctt ttgaatttgc tgggctgtga
     7441 tttcttgatt ttctggctgg ataatggttg cttcaaaccc aaagtgttga accaagtaat
     7501 caattgtttc aaggacagca tggtgctcga tggcagttgt gatgatatgt tttccttgtt
     7561 cttggtgacg aagacagtag ccaatgatgg tagtattatt gccttcagtc ccaccagaag
     7621 tgaaaaagat atgttgaggt tttgtcctta gtaactgggc tagttcctga cgggcttctc
     7681 gcaagagttt gccagcttga cgaccatgac catgaatact agaaggattt ccgtgggttt
     7741 cttgcataac cttggtcata gctgaaatag caactgctga cataggagtc gttgcagcat
     7801 tgtccaaata aatcaaagaa tcaccttatt tctttttatt gtaggcaaag agtgggctga
     7861 ctggttttct ttcgtgaata cggacgatag catcaccaat taactcacta gcagtgatgt
     7921 agcatacatt tttaggagtt ttttcttttg ttgctactga atcagtcaca agaatttctt
     7981 taatattagt attgtcaaga agctcagcag ctccctcgac gaagagaccg tggctagaaa
     8041 cagcataaat ttctgtagct ccttcacgtt caacgatttt agaagcttca gagaaggtac
     8101 gtcctgtatt taaaatatca tcaatcaaga tagctttctt accttcaaca tcaccaataa
     8161 tataaccttc gttacgagtt gcatcgtctt gagggtagtc gataatggcg ataggagcat
     8221 caagatattc agccaggcta cgcgcacgtt tgacacctga atttttaggg ctaacgacaa
     8281 caacatctga accaagcaat cctttatcgc agtaatgttt tgcgaatagg ggaacagtga
     8341 aaagattatc cactggaata tcaaagaaac cttgaacctg aacggcatgc aaatcaagag
     8401 tcaggatacg atcaactcca gccttaacca gcatattggc aactagtttt gctgtaagtg
     8461 gctcacgagg acaagcaatg cggtcttgac gtgcatagcc aaaatatgga aggacaacgt
     8521 tgatactgtg ggcacttgca cgcacacaag catcgaccat gattaacaat tccattaggt
     8581 ggttgttgac agggaaactt gttgattgga tgatgtaaac atcataacca cggacacttt
     8641 cttcgatatt tacttggatt tctccgtctg aaaattgacg tgatgatagt tttccaagtg
     8701 ggacaccaac agcttgtgca attttttgtg caatctcttg gttagagttg agtgcgaaaa
     8761 gtttcatgtt ttttctatct gacattatag accgtcctct gtaaacttta taaatcctag
     8821 ttatatttac cttacatata tgaactggga tttgtgtatt tttatctttt ctattttacc
     8881 aaaaaatgga gattatttca gctatttttc atacttttga caaatcgaac caattttgaa
     8941 ggagcttttt ggtaggaaat ctgatttttc tctaaaaatt gtcggaaatc ctgtttgcct
     9001 tgctcatgat tttccacttc aagctccaat tcgtaatctg ttatatcaaa gtatcggctc
     9061 tgatccagtg ccatgagacc aatagctgtt ttcatttcat agcgaagcgt tgttagacaa
     9121 ccaagaacct gccagttctt actttggata ccatgtttcg ccaattcatc cagtactagc
     9181 ccttgaggaa gttcttcctt actcagatag ttctcagcat cttttagttg caatttttgg
     9241 ttgtattcca tgtttccaac actctgcggg actttgagtg tcaactcagc ccagtcttca
     9301 aaggttcgaa tgcgcatagc gactttcttt tctcgcagtt caaaatcagg cgtgtcgatg
     9361 tagtaatttg tttgaagaac aggagtgaca cctgtgaact ggtcttttag acgattgtat
     9421 tcatcttttt tcaatagtgt tttcaattca atttctaaat gtttcatttt tcttaccttt
     9481 ttttatcgtt gaaagcggat ttatggtata ataagcattg tatttattgt atatgaatct
     9541 ggagaaaaaa tcaaagatat ttttgacgga taatatgaga acaagggaga atatatgacc
     9601 ttagaatggg aagaatttct agatccttac attcaagctg ttggtgagtt aaagattaaa
     9661 cttcgtggta ttcgtaagca atatcgtaag caaaataagc attctccaat tgagtttgtg
     9721 accggtcgag ttaagccaat tgagagcatc aaagaaaaaa tggctcgtcg tggcattact
     9781 tatgcgacct tggaacacga tttgcaggat attgctggct tacgtgtgat ggttcagttt
     9841 gtagatgacg tcaaggaagt agtggatatt ttgcacaagc gtcaggatat gcgaatcata
     9901 caggagcgag attacattac tcatagaaaa gcatcaggct atcgttccta tcatgtggta
     9961 gtagaatata cggttgatac catcaatgga gttaagacta ttttggcaga aattcaaatt
    10021 cgtactttgg ccatgaattt ctgggcaacg atagaacatt ctctcaacta caagtaccaa
    10081 ggggatttcc cagatgagat taagaagcga ctggaaatta cagctagaat cgcccatcag
    10141 ttggatgaag aaatgggtga aattcgtgat gatatccaag aagctcaggc actttttgat
    10201 cctttgagta gaaaattaaa tgacggtgta ggaaacagtg acgatacaga tgaagaatac
    10261 aggtaaacga attgatctga tagccaatag aaaaccgcag agtcaaaggg ttttgtatga
    10321 attgcgagat cgtttgaaga gaaatcagtt tatactcaat gataccaatc cggatattgt
    10381 catttccatt ggcggggatg gtatgctctt gtcggccttt cataagtacg aaaatcagct
    10441 tgagaaggtc cgctttatcg gtcttcacac tggacatttg ggcttctata cagattatcg
    10501 tgattttgag ttggacaagc tagtgactaa tttgcagcta gatactgggg caagggtttc
    10561 ttaccctgtt ctgaatgtga aggtctttct tgaaaatggt gaagttaaga ttttcagagc
    10621 actcaacgaa gccagcatcc gcaggtctga tcgaaccatg gtggcagata ttgtaataaa
    10681 tggtgttccc tttgaacgtt ttcgtggaga cgggctaaca gtttcgacac cgactggtag
    10741 tactgcctat aacaagtctc ttggcggtgc tgttttacac cctaccattg aagctttgca
    10801 attaacggaa attgccagcc ttaataatcg tgtctatcga acactgggct cttccattat
    10861 tgtgcctaag aaggataaga ttgaacttat tccaacaaga aacgattatc atactatttc
    10921 ggttgacaat agcgtttatt ctttccgtaa tattgagcgt attgagtatc aaatcgccca
    10981 tcataagatt cactttgtcg cgactcctag ccataccagt ttctggaacc gtgttaagga
    11041 tgcctttatc ggtgaggtgg atgaatgagg tttgaattta tcgcagatga acatgtcaag
    11101 gttaagacct tcttaaaaaa gcacgaggtt tctaagggat tgctggccaa gattaagttt
    11161 cgaggtggag ctattctggt caataatcaa ccgcaaaatg caacgtatct attggacgtt
    11221 ggagactacg ttaccattga cattcccgct gagaaaggct ttgaaacctt ggaggctatt
    11281 gagcttccat tagatattct ctatgaggat gaccactttc tagtcttgaa taaaccctat
    11341 ggagtggctt ctattcctag tgttaatcac tctaatacca ttgccaattt tatcaagggt
    11401 tactatgtca agcaaaatta tgaaaatcag caggttcaca ttgttaccag actagatagg
    11461 gacacttctg gcttgatgct ctttgccaag cacggttatg cccatgcacg attagacaag
    11521 cagttgcaga agaaatctat cgagaaacgc tactttgctt tggttaaggg agatggacat
    11581 ttggaaccag aaggggaaat tattgctccg attgcgcgtg atgaagattc cattattacc
    11641 agacgagtgg ctaaaggcgg aaagtatgcc catacttcat acaagattgt agcttcttat
    11701 ggaaatattc acttggtcta tattcacctg cacactggtc gaacccatca aatccgagtc
    11761 catttttctc atatcggttt tcctttgctg ggagatgatt tgtatggtgg tagtctggaa
    11821 gatggtattc aacgtcaggc tctgcattgc cattacctat ccttttatca tccattttta
    11881 gagcaagact tgcagttaga aagtcccttg ccggatgatt tcagtaacct tattacccag
    11941 ttatcaacta atactctata aaaactgtct cagagtataa ttattatctt aaaggagaaa
    12001 actcatggaa gtttttgaaa gtctcaaagc caaccttgtt ggtaaaaatg ctcgtatcgt
    12061 tctccctgaa ggggaagagc ctcgtattct tcaagcaaca aaacgcttag taaaagaaac
    12121 agaagtgatt cctgttttgc ttggaaatcc tgaaaaaatt aaaatttatc ttgaaattga
    12181 aggaatcatg gatggttatg aggtcatcga ccctcaacat tatcctcaat ttgaagaaat
    12241 ggtttctgcc ttggtggagc gtcgcaaggg caaaatgact gaagaagatg tacgcaaggt
    12301 tttggttgaa gatgtcaact actttggtgt gatgttggtt tacttgggct tggttgatgg
    12361 aatggtgtca ggagcgattc actcaacagc ttcaacagtt cgcccagctc tacaaatcat
    12421 caaaactcgt ccaaatgtaa ctcgtacttc aggagccttc ctcatggttc gtggtacgga
    12481 acgttaccta tttggagact gtgccattaa tatcaatcca gatgcagaag ccttggctga
    12541 aattgccatc aactcagcaa tcacagctaa gatgtttggc atcgaaccta aaattgccat
    12601 gttgagctat tctactaaag gttcagggtt tggtgaaagc gttgataagg tcgttgaagc
    12661 aactaaaatt gctcacgact tgcgtcctga ccttgaaatc gatggtgagt tgcaatttga
    12721 tgcggccttt gttcccgaaa ctgcagctct gaaagctccg ggaagtacag tagctggtca
    12781 agcaaatgtc ttcatcttcc caggtatcga ggcaggaaat atcggttaca agatggctga
    12841 acgcctgggt ggctttgcgg ctgtaggacc tgttttgcaa ggtttaaaca agccagttaa
    12901 tgatctttct cgtggatgta atgcagatga tgtttacaag ttgaccctca tcacagcagc
    12961 tcaagcagtt catcaatagt gaaaactata aagtgatata ctatgctata ctgtagttat
    13021 gaaactatgt acgaaaagca ctgccattaa ttcctgagaa ctaaattact gattggtgtc
    13081 aaaaaggaaa acttccaagc gatgatatcc tgtctataca cgacctatag aaatctgtaa
    13141 tatacatatc cgtaaaacga taaattccct ttttgatttt aaatgagtat gaaaagagaa
    13201 ttttttggct ctttgtcaac tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa
    13261 ttttgtcctt tcttttttga tgttcaaagc gataaaaatc cgttttttga agt
//
LOCUS       DBEJNA010000046        13263 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEJNA010000046 DBEJNA010000000
VERSION     DBEJNA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.46"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(120..557)
                     /locus_tag="ACL3JB_001820"
     CDS             complement(120..557)
                     /locus_tag="ACL3JB_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0686501.1"
                     /translation="MSQEVINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(642..3275)
                     /gene="polA"
                     /locus_tag="ACL3JB_001821"
     CDS             complement(642..3275)
                     /gene="polA"
                     /locus_tag="ACL3JB_001821"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0686502.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDY
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(3773..4718)
                     /locus_tag="ACL3JB_001822"
                     /pseudo
     CDS             complement(3773..4718)
                     /locus_tag="ACL3JB_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175244.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(4836..5804)
                     /locus_tag="ACL3JB_001823"
     CDS             complement(4836..5804)
                     /locus_tag="ACL3JB_001823"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0686503.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(5949..6618)
                     /locus_tag="ACL3JB_001824"
                     /pseudo
     CDS             complement(5949..6618)
                     /locus_tag="ACL3JB_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            complement(6643..7140)
                     /locus_tag="ACL3JB_001825"
     CDS             complement(6643..7140)
                     /locus_tag="ACL3JB_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0686504.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7213..8574)
                     /gene="radA"
                     /locus_tag="ACL3JB_001826"
     CDS             complement(7213..8574)
                     /gene="radA"
                     /locus_tag="ACL3JB_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0686505.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8588..9103)
                     /locus_tag="ACL3JB_001827"
     CDS             complement(8588..9103)
                     /locus_tag="ACL3JB_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0686506.1"
                     /translation="MKIIFVRHGEPDYSELEERSYIGFGINLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9105..9548)
                     /locus_tag="ACL3JB_001828"
     CDS             complement(9105..9548)
                     /locus_tag="ACL3JB_001828"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0686507.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9605..9702)
                     /gene="ffs"
                     /locus_tag="ACL3JB_001829"
     ncRNA           complement(9605..9702)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3JB_001829"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(9735..10202)
                     /gene="tadA"
                     /locus_tag="ACL3JB_001830"
     CDS             complement(9735..10202)
                     /gene="tadA"
                     /locus_tag="ACL3JB_001830"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0686508.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGATGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(10403..11689)
                     /locus_tag="ACL3JB_001831"
     CDS             complement(10403..11689)
                     /locus_tag="ACL3JB_001831"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0686509.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(11920..12156)
                     /gene="comW"
                     /locus_tag="ACL3JB_001832"
     CDS             complement(11920..12156)
                     /gene="comW"
                     /locus_tag="ACL3JB_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0686510.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12416..13231
                     /locus_tag="ACL3JB_001833"
                     /pseudo
     CDS             12416..13231
                     /locus_tag="ACL3JB_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259226.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4121 a         3212 c         2202 g         3728 t
ORIGIN      
        1 gtatctacaa cctcaaaacg gtgttttgag cagcccgcgg ctagtttcct agtttgctag
       61 tgtgctcttt gattttcatt gagtataaca caaaaggtag cccatcagct acctttttct
      121 tatgcttcct caatcaagcg agtatgttct ctcttgatac agcgattcat cacgatatca
      181 tcacatccac catcacgcaa aatctctttc gcttctaaac tttcaagtcc tagctgtgcc
      241 caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca catcgggcag aaattcactg
      301 cgacgataaa cattgacaat atctacagga aaaggaattt cagcgaggct agcataagcc
      361 ttttcaccca agatttcgcc acctgccgcc ttgggattga ctgggatgat tttatagccc
      421 cgagcctgca tttcctttgt cactcgattg ctggttgttt cttcacggtc agacaaaccc
      481 accacagcaa gggttttact cgttgcgaga tactgacgaa tcacgccatc acttggattg
      541 ataacttctt gactcataga aatcctcctt tttcatcagt atagcacatt ttgaaaaggt
      601 ttgcagaatt ctactacaaa aaaggaggac tagccccctt tttatttagc ctcgtaccag
      661 gttgcccctt cattctcatc tgcgataaga ggaacactga gttgaatggc ttcttccatg
      721 gtttgtttca ccaatttttt catctctacc aattcagatt taggcacttc aaggacgatt
      781 tcatcgtgca cttgtaacag catcttagtc tgataaccac ctgcaaccaa ggctttatcc
      841 agctgaatca tggcaatctt gagaatatct gctgccgaac cctggatagg tgagttgata
      901 gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg aattgatatc tggcaactca
      961 cggcgacgct taaagagggt ctctacatag cccttatcac gcgcctcccg caccacttca
     1021 tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg tatcaatgta ggctttggct
     1081 tccttacgac taattcccaa attattagac aagccaaagt ctgaaatccc ataaaccact
     1141 ccaaagttaa ctgccttggc attgcgacgg tcatttgcag tcacattatc aggacgctca
     1201 atgccaaaga cccgcatggc tgtcgaagta tggatatctg ccccctcttg gaaggcctta
     1261 atcaagtgct catccttaga aatatgcgcc aaaacgcgca attcaatctg tgaatagtca
     1321 gagctgagta gcacactatc ctcccactct ggcacaaaag ccttccgaat caagcgccct
     1381 tgttccaatc gggcaggaat attttgcaag tttggatcca cactagacaa acgcccggtc
     1441 tgggtcaaat cctgcatata gcgagtatga atctttccat cagccaaaat ccagtcctgc
     1501 aagccaatta cataagtaga ttgaatctta gcaatttgac ggtaatccag gattttctta
     1561 acaatcggag caataggagc gagacgctcc aacacatcca ctgctgtcga ataacctgtc
     1621 ttggttttct tagtgtattc tagaggaagt cccaatttct caaagagaag cacgcccaac
     1681 tgcttaggcg agttgacatt aaactcctca ccagccagct cgtaaatctc ttgagtcagt
     1741 ttttcaatga caagctcatt ttcagcctgc atctcaagca aggtctcttt cttgaccaca
     1801 atcccagcaa tttccatctt ggcaagaaca aaagccagag gttgctccat atcataaaga
     1861 agctctaatt gcccattttc gctgagtttt tcaagtaaaa taggctctgt ttctaccaaa
     1921 acagcaagtt tacaagctaa atgttccaag aatttctcac gttcaggaat ggccttttta
     1981 acacccttac cgtagaaagt ttcatcatca accaagtaag tctgaccata aagactagcg
     2041 atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt atttagccaa acggatgtca
     2101 aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa gaactttaac cttcttaaag
     2161 tcataaactc tcagagatgt tttttctaag aaatccttga aaatcgggtc ttgcaacagc
     2221 tcaagcttgt ctgtggcata gagcttatcc ccacaagacc aggcaaatcc aaccaaatta
     2281 tccgtatggt aattctcacc aaaaagctca aagtggaaga tagactcttc actcagcata
     2341 tcttgactga tttggtcaac aatagtaaaa tccaaactct cagacacatc agctgacgac
     2401 acatttaaag cctgcttgag ctgtttgaag cccatctcat cgtaaaattt cccaagattt
     2461 tcaacatctg gaccactata gaccaagtcc tctaaaccaa tcgcaatcgg tgccttggta
     2521 tcaatggtcg ctagtgtttt agacaaaaag gcctgttcct tgtcattgat gagattttcc
     2581 ttcatcttag aagtcttcat tccatcaata ttttcataaa tcccctcaag cgaaccatgc
     2641 tccagcaaga gcttaatacc cgtcttttca ccgactttgg tcaccccagg gatattatcc
     2701 gacttatcac ccatgagcgc cttgagatcg ataaactgag ctggtgtgag gcccatttct
     2761 tccatgaggt aatctggcgt aaaggcctca aactcagcca cacctttctt ggaaatttca
     2821 accaccgtat gctcatccgt cagctgaatc aaatccttgt ccccactgac aatggtaata
     2881 tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa tgatgtcatc cgcctcatac
     2941 tgagccagct catagtgacg aatccccata taatccagca actcacgaat gaaaggaaat
     3001 tgctcacgaa actcatcagg agtcttggcc cgaccaccct tatagtccgc atacatctct
     3061 gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa tatgactcgg ctcaacccgc
     3121 tccaacaaat gactcaacat caactgaaaa ccataaatcg cattggtatg caaaccagcc
     3181 gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa acgcccgaaa agctacagaa
     3241 gacccatcaa tcaataataa ttttttctta tccatacacc cattataaag gaaagaatca
     3301 aaaaatacca ttgggaagag ctagagcaag tatttttcaa actttttccg aataaataga
     3361 tagagccaga gaatttagta aacctagatt taaaaatgtg ctataatata ttgaatctat
     3421 aatagtacac cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagagt
     3481 tattcacatc ttatttcaac tcactataga aggaggaaaa ggagggctgg gtggctaact
     3541 tcattataga actttcaaaa agatgaaaaa atagcgtcaa agaggctttt ttctctttaa
     3601 aacaggaaat ctcaaagaca atcttgcgac tatccaaact gtatgaatag cgagacataa
     3661 cttacttcgc taatactatc ttataaaaag atagaaatgt caagcaaaaa tgacaagtat
     3721 tttgataata aacttgccat cccatcaact ttctactata taaagtatga actcatagca
     3781 aggactcaaa ctcagccacg gtcatgccta attgctcact cgcaacctca ggtgttagaa
     3841 gaccttgacg tactagattt actaaaccta cttttaatcc ctcttcaagg ccttcttctc
     3901 gtccttgttc acgaccctct gcacgaccac gttcaatacc acgctccagt ccttgttcaa
     3961 ggccttcagc cctagcagtt tccaaggcat agtcctgtgc taacaagact tgttcttctc
     4021 gcatatgtag ttgactaaac attttcctgt cctcttcgga ccagctcttg tagtccagca
     4081 gttgatttgc ttgggtaatg gctcgttgcg gttgctgggt aaagggcttg ttgccgaaaa
     4141 actccaacca tggcttgcga accttgtctt tgctggtttc tctgtatttt ttaattccaa
     4201 gaatgccatc ttaaccagat ggttttcctg tccattgttg gtaatcgcca atacctcacc
     4261 tgttgtgtct tcgcgcatac taaagctatg aaaagccagg tcatctgaga aataattact
     4321 atccacgata gcaatggcgt aaacaggagc gatgtgtttg tagctctagt gagtatcacc
     4381 ttctcgctga cgaatttttt caagattttg attaacctga ctgcacaggt aagcccacaa
     4441 gcgattgatg aaaaattctg atgatggact tgaatctcaa taattacttg agtactgtta
     4501 tccaactccc ccaagacgtc tatactggta taaaaatcct gcaccgagta aggcatggag
     4561 agtaatacgt gaatattgct accctccaaa atggtcacat ttttggctgg caaatccagc
     4621 atatcgcgaa taaattgaca agtgatttct ggattgctaa agattttctt agctaccaag
     4681 tcattggttg ggctaatgcc cggatgacgt acagtcatat ttcttctctt tttattatat
     4741 cacagtttta aatctagctt tactagattc accgctacta tctatttatt cggaaaaaag
     4801 acgaaaaaac ctgagaatca tctcaggctt ggtcattaaa tttttttctc aatatcgaaa
     4861 agtggagaaa gtggtcgttt ttcatgaata cgtacgatag catcccctag gagatgagcg
     4921 attgaaatct gctcaatctt atcaatcaaa cgctcttctg gcagatagat ggtatccaaa
     4981 acaaccaatt tcttaatagc tgatttttgg atattgtccg tagcaggacc agaaagaact
     5041 gggtgcgtac agcttgcata gacttcaaca gcaccagctt ccgcaagagc atctgccgca
     5101 tgacaaatcg ttccagcggt atcaatcata tcatcaatca agatacaagt cttgccttca
     5161 accttaccga tgatgttcat aacttcacta gtattcatct tatcaacgct acgacgttta
     5221 tcaataatag cgatagatgt tttcaaaaat tctgccaact tacgagcacg agtcacccct
     5281 ccatggtctg ggctgacaac cacatagtca gaaccaacca taccacgacg ctcaaaataa
     5341 tctgcaatta gaggagcacc catcaaatga tccacaggaa tatcgaagaa tccttgaatt
     5401 tgcgcagcat gcaagtcgat ggtcaataaa cgatccactc cagctacttc aagcatattt
     5461 gcgacaagtt ttgaagtgat tggctcacgc gctctcgcct ttctatcctg acgtgcatac
     5521 ccatagtaag gcatgacaac attgacagat tctgcactcg cacgcttcaa agcatctacc
     5581 ataatcaaaa tttcaagcag attgtcattt acaggcgaac tagttgattg taggataaag
     5641 acgtgtttcc cacggattga ttcttcaatg ttgacctgaa tctctccatc tgaaaattgg
     5701 cgaacacttg atttccccaa ctctatccca atctcctgcg ccacacgttc tgccaattct
     5761 ttattagaag aaagggcaaa cagctttaaa tcagaaaaag acatgatttc ctccggtata
     5821 tatgtatcgc ttgtgctttt cacaagattt tccatctacc attgtagcgc tttttgcact
     5881 atttttcaat caaaaataaa agaagggcac catatttgta cccttgcatc attcttttga
     5941 aaaatattct aggtcatcaa ctcattgtgt ttctcaacaa agcaataagc atgataataa
     6001 ccatagagag caatagccgt aaccactgga atcgctaaag gcaactctgt ttccaactcc
     6061 acaaaaggag agttaaacaa taagaccctg tttcttgcca accttctgtc ctttataggc
     6121 tctgtaaagc aagtaaacac ctactacagc tagacctgaa aaagtccagt gagaggcaat
     6181 tccaagtaaa aacaaaaatt ttaattttcg cacaggaatc aaagccaaaa caaaaacaag
     6241 tggcaataat ttcaagggtt cttctaccaa aggagccaca atagcacttt caaaggcatt
     6301 taaaaatgta ctatctggga aaagaacccc cagtaaatca tggatataag tattagcaaa
     6361 actagacaac cagcctgaaa ggaacatccc tcccaataaa gacagaatca aaaccttctt
     6421 tggcaattcc cattttttcc caatacggaa gagaaaataa agagccggaa tcatgtaaaa
     6481 gagagctaga aagatagaaa ctcccattag tccatattcc gcacctgacc tcgaaccgtc
     6541 cgtatagtag atggtttcat actgtaaacc aatacatagc aataaaataa aaataaataa
     6601 aatactgctt ttcttcatac actttctttc taaatgaagt atttataatt ctacgactgt
     6661 catacttcct gtatcaacat tgtaaatggc accagagata atgacatcgt ctggtattag
     6721 gggagactcg ataagcagtt gcatatcctc gcgtacactc tcttctatat cttggaaggg
     6781 caagaagtcc tggtctgaca catctacacc taattcctct tttaaatact cctgaaaagg
     6841 ttcattttca aaggtctgag caccacagtc tgtatggtgc aataccacaa tctctcttgt
     6901 ccccatttgt tgctgggaaa taactagcga acgaatcatg tcttcagtca ctcgaccacc
     6961 tgcattccgc aagatatgag catccccaag tgccaagccc agagcttgcg caacgtgcag
     7021 acgagagtcc atacaggtca caatagctac tcttgttttg ggtttaagtg gcagatttaa
     7081 ctgcccatgt agggcaacat aagcctgatt ggcttgcata aactgttcaa aatacgacac
     7141 gattccctcc ttgaaaattt gatagtcaaa tatttctcct atcttatcat ttttaagaga
     7201 atttgtcacg gattatgcaa agaccttttt caagacttcc tgaatcgttg tcacgccaat
     7261 gacctgaatt tccttaggca gagtgattcc tgtcaaggaa ttcttaggta cataaatctt
     7321 agtaaagccc agtttagcag cttcgttgat gcgttgctca atacgattca cgcgccgaat
     7381 ctctcctgtc aagcccagtt ctccgacaaa acattcctga ggattagttg gcttgtcttt
     7441 gtagctcgaa gcaatagcaa ctgcaacagc caagtcaatc gcaggttcat ccaatttaac
     7501 accaccagca gatttgagat aggcatcctg attttgcaag agaagccctg cccgtttttc
     7561 caaaacagcc ataatcaagc tagcacggtt aaaatcaagt cctgtcgtag tacgcttggc
     7621 atttccaaac atggtcggtg ttaccaaagc ctgaacctcc gccaaaatcg gacgcgtccc
     7681 ttccatggtt acaacgatgg aggaaccagt cgccccatcc aaacgctctt ctaggaaaac
     7741 ttgactcgga ttgagtacct caaccaagcc gcccgactgc atctcaaaaa tcccaatctc
     7801 attagtggaa ccaaaacgat ttttgaccgc tctcaaaata cgaaaggtgt ggtgacgctc
     7861 cccttcaaag taaagcaccg tatccaccat atgctccaac atacgaggcc cagccaaggt
     7921 tccttctttg gtcacatgac ctacgataaa gatggcaatg ttattggtct tggccaactg
     7981 catgagttca gcggtcactt cacgcacctg agaaacagac ccctgcaccc ctgaaatctc
     8041 aggagacatg atggtctgga tggaatcaat aatgagaaag tctggctgga tacgctccac
     8101 ttctgcacga acactctgca tattggtctc tgcatagaga taaaactcac tatcaatatc
     8161 acctaagcgc tctgcacgta gtttaatctg ctgggcagac tcctccccac tgacatagag
     8221 aactgtcccc acttgggaca actgggttga gacttgtagg agaagagttg atttcccaat
     8281 cccaggatcc ccaccgatga ggacgagact tcctggtacc actccgcctc caagcacacg
     8341 gttgaattcc tccatctccg tcttggttcg attgacattg atggaagtca cctcagctag
     8401 tttcatgggc ttggttttct cacctgtcaa ggacacacgc gcattcttga cctcggcaac
     8461 ctcaacctct tccacaaaag aagaccaaga cccacagttg gggcaacgtc ccagatattt
     8521 aggggaatta tacccacaat tttgacatac aaatgtcgct tttttctttg cgatgacaaa
     8581 cctctttcta tatctctaac tcacactcaa tcacttggca aaaatcaatc ttctcatttg
     8641 gcacaaactg gcgcatgagc attcgatgag caacaactac cacagtctga tgttctcgat
     8701 acttagacat acattctaga aaccgagact tcatttccgt agctgtctca tattgaatag
     8761 gactattagg aagcaactcc cccttgtttt ctaaaaacag tcttctagct gtttcaaagt
     8821 tttctattcc tgttttatag acctgccatt catgtaataa aggctctact cttaaaggaa
     8881 gacccgtagc acagaccaca tacgaagccg tttctaaagc tcttgtgact gcagaagata
     8941 cgattatttc agctgacgag agtaaaggat ttttgctcaa tttctggact tgctgccgtc
     9001 ccatctcaga caagggtgcc aaatttatcc caaatcctat ataagaacgc tcctctaact
     9061 cactgtaatc cggctcccca tgacgtacaa agataatctt cattctagtg ccctgtcgat
     9121 ccaaatccac cagttcgaac gccatcagct gcatctccat ctgcaattaa gaaagtagca
     9181 aaaacagcct ggacaatacg ctccccaact tcaagaacaa cctcttggtc tgtgatattc
     9241 ttcatctgcg caaaaatatg cccttcattt ccaggatttc cataataatc cccatcaatg
     9301 accccaactg agttaattaa aaccaagccc ttcttacgag gatttgaaga acgatcatag
     9361 aggtagagaa cctcagtcgg ctgcatataa gccttaaccc ctgtcggaac caagacaatc
     9421 tctcctggcg caacaactgt acgcacagca acctttaagt cgtaaccagc cgcatgcgct
     9481 gtctcacgct tgggcaataa attttcatct gtaaaactcg aaaccaattc aaaaccacga
     9541 attttcataa ttttctcttt tctattatca tttattctag attattctat cttatttatt
     9601 cggaaaaagc acgaaaaaaa gagcacacaa ttcaaatcgc ttagggctgc tggattcctc
     9661 ccctgacccg cttcacgcag aactgttgct ccactattta ttatatcaca ttcctattca
     9721 ttttaaaagc aaaattattt tttccgtcta tttctaaaaa agtcctgcat gatagctgca
     9781 cattcatctt ccaaaattcc cgtttcaacc tctacacgat ggttaagacg ctcatctgtc
     9841 aagatatcgt acaaacttcc agtagcgcca aatttctggt ttttagcccc atagaccaca
     9901 tttggaatgc gggcaagccc aatcgcccca ctacacatga cacaaggttc aatggtcaca
     9961 aaaagtgtgc aatccagcaa gcgccagctc tcctcactca agttcgcatc ctctatagcc
    10021 ataatttccg catgcataac cgctcgctgt aattcctcac gcgcattatg cccacgacca
    10081 atgatttccc catctttgac aatcacacaa ccaattggaa tttcatcgtg ttcaagagca
    10141 atctcagcct ctctcaaagc ctccctcata aagacttctt tttcttcaag cgtataatac
    10201 atctcttttc tcttttccta cttatcgatt ttattattat atcatgaatc ccaacacaaa
    10261 aaaagccacc gaatgcggtg actctatagg gagattatta tgaaaaagaa aagtttagga
    10321 tatttgttac aacaagttag gaggtcttct tgtaactgtc tatagtatac ccgacctatc
    10381 ttaaacaaat cttaaaaatc tcttaggacc aaacactttc taaaatattt gtttgttcac
    10441 gaccaggacc tactgagaaa gtagaaatac gaacgccaac caattcactc acacgacgaa
    10501 catagttacg cgcattctca ggaagatctt ccaaattgcg agctccggta atatcttctg
    10561 accaacctgg caactcttca tagataggct tgcaacgttt caattgctca agactagctg
    10621 gatagtagtc aatacgttga ccgtcaagat cataggccac acaaattttc acagtatcca
    10681 agccgctcaa aacatcaata gagttcaaag aaaggttagt aataccagaa acacgacggc
    10741 tatgacgcat cacaactgag tcaaaccaac ctacacgacg tggacgacca gttgttgtac
    10801 catattcatg acccacttca cggatacgtt ctcccacttc atcaaacaac tcagttggga
    10861 aaggaccatc tcctacacga ctcgtataag ctttacatac acctacaacc ttgtcaatct
    10921 tgcttggacc gataccagaa ccaattgtca caccaccagc tacagggttt gatgacgtaa
    10981 caaatggata agtaccttga tcgatatcta gcataacacc ttgtgcacct tcaaaaagca
    11041 cacgtttgcc attatcaagc gcatcattca agataacaga tgtatctatc acgtatttct
    11101 tgatttgttg accatattcg taatattctt caaaaatatc atcgaaaaca atcgctttac
    11161 tgtcatacaa tttttcaaaa agacgattct tttcagcaag gttacgttct aaacgctcac
    11221 ggaaaatatc tttatctaaa agatctgcaa tacgaattcc aacacgagca gccttgtcca
    11281 tataagctgg accaattccc ttaattgtcg taccaatctt attgtcgccc ttagcttctt
    11341 cttgcaagcg atccaactcg atatgataag gcaaaataac atgcgcacga tcagaaatac
    11401 gcaagttatc agttgttaca ccttcctcat gaagatagct caactctttt acaagagatt
    11461 taggatttac aaccatacca ttcccaatga cagatatttt ttcagggaag aaaatcccag
    11521 atggaatcaa gtgcaactta aatttcttac cgtcaatcac aatcgtgtga ccagcattat
    11581 caccaccttg gtaacgtgca attacttctg cattcgctga aaggaagtct gtaatcttcc
    11641 ctttaccttc atcaccccat tgggtaccta caacaacaac tgaagtcata attttgtctg
    11701 agccctcagg ctcttccttt ctcacataca tggcaggact ctcacctgca attatatctt
    11761 acaatttatt ataataaaaa atcgcctttt tatcaagaag aaacaataga aagatttgct
    11821 atttccaact attaaaaaat gatttagaaa aattactagc tatttactat tatctttcca
    11881 taaaagagta aattagttcg gaaatttact aaaattacct caacaagaaa taaaaccccg
    11941 attcattacc aatttttcaa gatacaaacg ataagcaaca cgataatggt aaacgataaa
    12001 atccctacga caaccaatgc catatctcac taaataataa attaaaaatt taaaatgaac
    12061 atgttcccag tcaaaattat caccaaatgt aggaccatac tcttcttcaa tactatcata
    12121 gaaattagcc atctgctcat aaattttttg taacataatc aaatactcct tttctttttt
    12181 ataaacttat tctaacaaaa aattttacac attcactatc aattcctgaa ttgttaaaat
    12241 accagcctca acaagataaa aataggaaaa gttgacagaa tagaaacaaa tttgctacct
    12301 aaatttcaaa cgattaaagt tctaaaaaga ccgccttaaa acttttgggt aaatcctatt
    12361 agaactataa tatttttata taggtattat ggttctgatt ttctagtata aaaaaattca
    12421 aactagaatt cttcttataa aagtaaaagg ccgttttaag tgctatcatt gctcaaaaat
    12481 ggaggtcgct gagacttcta tcgtcaagaa gaatcatcaa attccttgta tcatcaacca
    12541 aaagattgct cagaagctaa ttgaaaagac ttctatgacc gacattgatc atcagttgtc
    12601 tatttcaatt tcaacttcaa ctgtcattcg caagatcaat gattttcact ttgagcatga
    12661 tttttcgcgt cttcctgaga ttatgtccta ggacgttgaa acagtccggg gagtgactgt
    12721 ttcaatcggg agatggagat gagctttatt gctcaagact ttgataagct caatatcata
    12781 actgttcttg agagcagaac acaagccatc atccgaaatc ccatgaatac aaggctatca
    12841 agcgatactg aaagctcatt caacaagata gtcagaaact gagtgataaa cgattttatc
    12901 gccctacttt tcgtatgcac ttgactaata aagaaattct agataaactt ttgagctatt
    12961 ccgaagactt gaaacaccac tataatctct atcagctctt gcttttccac ctctttttca
    13021 gactctgttt aaaaccttcc tcaaagataa agagaaaatc gtcaacgccc ttcaattacc
    13081 ttattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca agcacaatgc
    13141 ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg tcctttctag
    13201 attttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc tcgcctctaa
    13261 tat
//
LOCUS       DBEJNA010000047        11911 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEJNA010000047 DBEJNA010000000
VERSION     DBEJNA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.47"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(49..1185)
                     /gene="dnaJ"
                     /locus_tag="ACL3JB_001834"
     CDS             complement(49..1185)
                     /gene="dnaJ"
                     /locus_tag="ACL3JB_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0686511.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1587..1943)
                     /locus_tag="ACL3JB_001835"
     CDS             complement(1587..1943)
                     /locus_tag="ACL3JB_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR0686512.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1945..3768)
                     /gene="dnaK"
                     /locus_tag="ACL3JB_001836"
     CDS             complement(1945..3768)
                     /gene="dnaK"
                     /locus_tag="ACL3JB_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0686513.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4248..4772)
                     /gene="grpE"
                     /locus_tag="ACL3JB_001837"
     CDS             complement(4248..4772)
                     /gene="grpE"
                     /locus_tag="ACL3JB_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0686514.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4799..5833)
                     /gene="hrcA"
                     /locus_tag="ACL3JB_001838"
     CDS             complement(4799..5833)
                     /gene="hrcA"
                     /locus_tag="ACL3JB_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0686515.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKTLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKRIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(5997..6506)
                     /locus_tag="ACL3JB_001839"
     CDS             complement(5997..6506)
                     /locus_tag="ACL3JB_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR0686516.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7115..9448
                     /gene="hsdR"
                     /locus_tag="ACL3JB_001840"
     CDS             7115..9448
                     /gene="hsdR"
                     /locus_tag="ACL3JB_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0686517.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9461..10924
                     /locus_tag="ACL3JB_001841"
     CDS             9461..10924
                     /locus_tag="ACL3JB_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0686518.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            10924..>11911
                     /locus_tag="ACL3JB_001842"
     CDS             10924..>11911
                     /locus_tag="ACL3JB_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686519.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT         3682 a         2301 c         2301 g         3627 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agagattttc aaagagtatt attctccatc
       61 aaaggcatct ttaatatgat caaagaagcc ttttttcttt ggatttactt tcaagtcacc
      121 agcagccgcg aattctttca aggctacttt ttggcggtcg ttcaagcctg tcggtgttac
      181 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
      241 actacgtagg cggaatttct taccagtctg agttccctct ggaataacca attcaacatc
      301 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
      361 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ccacagaaac
      421 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
      481 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
      541 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttccttggcc
      601 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
      661 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
      721 accagagcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
      781 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
      841 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
      901 aaaaccaccg aagccacctg ccccattgaa accgccgaaa ccaccatctc caccaaaacc
      961 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
     1021 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
     1081 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
     1141 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
     1201 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttat gtcctagaaa
     1261 aaactatctt tttggcacag tccgtagccc gtgttcagtt acgaacaccc ttattccttt
     1321 ctattgatgt tctgaatcga accaccattt aggtcggatt caattccttt cttttatatt
     1381 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttcct ttctattgat
     1441 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
     1501 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
     1561 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
     1621 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
     1681 tgtatttcta atgatatcat agctgatacc atcgccgata caaatgcaga caacaatact
     1741 gaagtaacaa aattccttac cgcttcatca tttttgacac aactatcatg ctcagctaat
     1801 ataatttctc tatatatagt caaacattct actggaatat tatctataaa accttttgct
     1861 gcttcatagt tgtcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
     1921 tactcatcat ccaatacact catcttattt ttccgtaaac tctccgtcta cgacgtcatc
     1981 gcctgcgttt cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
     2041 ggcttgttcg tagagtttca cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt
     2101 cgctttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
     2161 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
     2221 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
     2281 atcagcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
     2341 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
     2401 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
     2461 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
     2521 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
     2581 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
     2641 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
     2701 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
     2761 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
     2821 gatacgagtt gaaccaccaa caaggataac ttcgtcgatt tctgacaagc tcaaacctgc
     2881 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
     2941 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagcct cacctgcagt
     3001 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
     3061 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
     3121 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
     3181 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
     3241 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
     3301 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
     3361 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
     3421 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
     3481 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
     3541 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtaactgc
     3601 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
     3661 agttgtgcgg tttccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
     3721 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
     3781 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
     3841 gcttgacttc gtcaatctct ttgactaaac tttgagccta aggtctcaaa atttgcgcaa
     3901 atagcaccac ggcgaagagt atcgtctttg gttcgcttcg ctcactatta caaagccaaa
     3961 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttatgtaaat
     4021 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
     4081 aaacgccata gcgattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
     4141 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
     4201 tcgtcaatct cctattttta ctgcgagctt tttacgagct ttgtatctta gttatacacc
     4261 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttgg
     4321 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
     4381 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
     4441 atcaagcttt cttgcaccat cgccaagccc ttcttcacat catctgtcaa accttcaact
     4501 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
     4561 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
     4621 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
     4681 tcagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
     4741 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
     4801 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca
     4861 aaacacggtt gaccacattg acttgattga ttagctgttg gtaatccaga ttaactggac
     4921 cgataatggc tagaattcca actccccgat aaggaatgag gaacttacta ctaatcaccg
     4981 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
     5041 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
     5101 ctgctagatt ggcaaaattc aagagattga ccttgcccgc catcacaatg ttttcgttga
     5161 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
     5221 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
     5281 cgaggaaacg ttcctgaatg attctcttca gtttcagcaa atcctcctgc aagaagttcc
     5341 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
     5401 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa ccgttgcctg ctcggctcaa
     5461 catccagtgc cactaccgta cagccactca ggtctgttag caagttagca gcctcttgca
     5521 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
     5581 tttcagccag tcggtcaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
     5641 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
     5701 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gtttttgatc
     5761 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
     5821 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
     5881 tgctaactca tgattctatt atacaccctt agaagagaat gtcaagacaa aaactcaaaa
     5941 aattagcact cttttatcaa gagtgctaaa aatcaatctg aagacctaga accttgctat
     6001 tcatctactc ggtatttcct ttttagtctg aaataaccat gaattagata agaaatcaga
     6061 aaagcatata aaacaaaaat aagaaagaaa gacatagaaa gatcctctct aaacaaactc
     6121 atacaaacaa caagaccacc taagaaagta gctgtacagg aacgaagtct agatcgcata
     6181 acttcccatt tgagcccctt actcatatag acttgatcct ctggaagtaa atcagaagac
     6241 gatttacgaa gaatcgaaca agaacctgct cctatcaatt cccaacctct atctctaaaa
     6301 tcttgcagtt cacgcttatg ctctttaaga aatctagaat catagatacg atagataaca
     6361 tcgtccggtt gaccttgctc aaaatagaac aaaccaaaac gactcgttct atacctccaa
     6421 cctttcaaat gcatctcatg taaatattct tctttcttgt ccaaatcaac aatggtgaaa
     6481 atccgaaatt ctactctgct attcattgtc ttaccccaaa attagaaaac atgcctggcg
     6541 ttatttagtt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
     6601 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac actttccaac
     6661 tgaaagaact acctccagta acaaactttg agaaaaacgg tagtagagct aaaaagagaa
     6721 gtaaaatagg aagcatccgc attgttaaaa tccgtttggc ataaaaaaat ctttatttaa
     6781 acgaaaatat tatagcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
     6841 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca gcccgactga
     6901 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcggaaaata gcggtgttat
     6961 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
     7021 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
     7081 gagaagtaga tttttagaat gcggagggtt caatatggtt gagtttataa agtctaagaa
     7141 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
     7201 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaggt
     7261 tagaggagat aaggctcgtc gtaaagaagg aaaaaaatca gactattcac tgtattacca
     7321 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
     7381 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
     7441 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
     7501 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
     7561 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
     7621 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
     7681 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
     7741 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcag atagaaacat
     7801 cttagtagac caaacgatgg ctgaagactt taagccattc gaaaaggtaa tgacgaaaat
     7861 tacaccaaaa cttttgactg ctcctgaaaa gttaaattct tttgaaattt atctagggct
     7921 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgacaaaga
     7981 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aagacagtaa
     8041 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
     8101 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
     8161 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gggttaattt
     8221 agatgtggat gtggatggtt atcgtccaga aactggaaaa gttgatgcta acggacaatt
     8281 aatagaagat aggtactacg gcaggaaaga ttttgataaa accattgtca ttgatgatag
     8341 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
     8401 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
     8461 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
     8521 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
     8581 tattgtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
     8641 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
     8701 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
     8761 caatttgttt gctgaccctg attttgatgg tgatccagtg aaggtgctag aaacaggtgc
     8821 gaaaacagtc agtggttcta cgcccggttt cgtagatgag gaaggtgacc cagtagaaaa
     8881 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
     8941 aaacgggaaa ctgattaccg aaagcctgac cgactacact cgaaagaata tcttaggtag
     9001 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcagataaga agaagcttat
     9061 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
     9121 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
     9181 attaaccaaa acggaacgta tcaataaact caaacaaagc ggatatttat ataaatatag
     9241 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
     9301 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
     9361 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
     9421 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
     9481 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
     9541 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
     9601 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
     9661 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
     9721 caagttattc aaagagttga aagagcttga aataacttca aatatgccta ttcgaaaaac
     9781 gattgttaaa tcagcttttg aagatgcgaa caactatatg aaaaatggcg tcttgttacg
     9841 ccaagtcatc aatgttattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
     9901 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
     9961 ttatacgcca cgtgcagcga ctgattttat tgccgaagtt cttgacccaa aacttggaga
    10021 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
    10081 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
    10141 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
    10201 tgaccctaaa attgttcatg gaaatacttt ggagaaaaat gttcgtgaat atacggatga
    10261 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
    10321 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
    10381 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
    10441 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
    10501 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
    10561 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
    10621 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
    10681 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
    10741 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gttttccaaa
    10801 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
    10861 aactttaaat cataagattg ataatgtatt agctgatatt ttgcagttgt tggaggacaa
    10921 ataatgacac cagaacaact taaagcaagt attctccaaa gagcgatgga agggaaatta
    10981 gtgccgcaaa atcccaatga cgaacctgca agtgaattat taaagagaat taaagctgaa
    11041 aaagaaaaac ttatcagtga aggaaaaatc aaacgagata aaaaggaaac tgagatattt
    11101 cgtggtgatg atgggaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat
    11161 gttccttatg atattcctga tacttgggag tgggtgaggt tttctacatt ggttgaaatt
    11221 gtcagaggtg gctctccacg accaatcaaa gattatctta cttctgaagt agatggaata
    11281 aattggataa aaataggtga tactgaaaag ggtgaaaagt atataaataa tgttaaagaa
    11341 aaaatcaaaa aatcagggct taacaaaact agatttgtaa aaaaaggtac atttttgtta
    11401 actaattcta tgagttttgg tagaccttat attttgaatg ttgatggtgc aatacacgat
    11461 ggatggttgg ctatttcgaa ctatgaaaac tcattaaata aagattacct attctatatt
    11521 ctttcatcaa atgtagttta ttctcaattt ctatctctaa ttagtggagc tgttgtgaaa
    11581 aacttgaata gtgataaagt tgcttctatt cttatccctc tccccccact atccgaacaa
    11641 caacgcataa tagaagcaat cgaatcagct ttagaaaaag tagatgaata tgctgaaagt
    11701 tataatagac tagaacagct agataaagaa tttccagata aactaaaaaa atctattctt
    11761 caatatgcta tgcaaggaaa attagttgaa caagacccaa atgatgaatc agtcgaagtt
    11821 ttacttgaaa aaatacgagc agaaaaacaa aaactctttg aagaaggcaa gattaaaaag
    11881 aaagatttgg acatttctat tgtttcccaa g
//
LOCUS       DBEJNA010000048        11690 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEJNA010000048 DBEJNA010000000
VERSION     DBEJNA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.48"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(81..542)
                     /locus_tag="ACL3JB_001843"
     CDS             complement(81..542)
                     /locus_tag="ACL3JB_001843"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0686520.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(509..652)
                     /locus_tag="ACL3JB_001844"
     CDS             complement(509..652)
                     /locus_tag="ACL3JB_001844"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0686521.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            920..1300
                     /locus_tag="ACL3JB_001845"
     CDS             920..1300
                     /locus_tag="ACL3JB_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0686522.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1400..1621
                     /locus_tag="ACL3JB_001846"
     CDS             1400..1621
                     /locus_tag="ACL3JB_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0686523.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1638..1952
                     /gene="trxA"
                     /locus_tag="ACL3JB_001847"
     CDS             1638..1952
                     /gene="trxA"
                     /locus_tag="ACL3JB_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0686524.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            2257..2790
                     /gene="queF"
                     /locus_tag="ACL3JB_001848"
     CDS             2257..2790
                     /gene="queF"
                     /locus_tag="ACL3JB_001848"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0686525.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            2802..2975
                     /locus_tag="ACL3JB_001849"
     CDS             2802..2975
                     /locus_tag="ACL3JB_001849"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686526.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSNHTYGKVKLTWFEEI
                     FEEYHTKKPCSSR"
     gene            complement(3000..3668)
                     /locus_tag="ACL3JB_001850"
     CDS             complement(3000..3668)
                     /locus_tag="ACL3JB_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0686527.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPTVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(3779..4570)
                     /locus_tag="ACL3JB_001851"
     CDS             complement(3779..4570)
                     /locus_tag="ACL3JB_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR0686528.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQELNAGFRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(4816..6612)
                     /gene="pepF"
                     /locus_tag="ACL3JB_001852"
     CDS             complement(4816..6612)
                     /gene="pepF"
                     /locus_tag="ACL3JB_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0686529.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRAMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(6623..7366)
                     /locus_tag="ACL3JB_001853"
     CDS             complement(6623..7366)
                     /locus_tag="ACL3JB_001853"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0686530.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(7368..8318)
                     /gene="prmA"
                     /locus_tag="ACL3JB_001854"
     CDS             complement(7368..8318)
                     /gene="prmA"
                     /locus_tag="ACL3JB_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0686531.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPFWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(8454..8882)
                     /locus_tag="ACL3JB_001855"
     CDS             complement(8454..8882)
                     /locus_tag="ACL3JB_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0686532.1"
                     /translation="MELEISDFLGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(8863..9951)
                     /locus_tag="ACL3JB_001856"
     CDS             complement(8863..9951)
                     /locus_tag="ACL3JB_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR0686533.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLVPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(9970..10440)
                     /locus_tag="ACL3JB_001857"
     CDS             complement(9970..10440)
                     /locus_tag="ACL3JB_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0686534.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(10731..11183)
                     /locus_tag="ACL3JB_001858"
     CDS             complement(10731..11183)
                     /locus_tag="ACL3JB_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0686535.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(11220..11399)
                     /locus_tag="ACL3JB_001859"
                     /pseudo
     CDS             complement(11220..11399)
                     /locus_tag="ACL3JB_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
BASE COUNT         3488 a         2717 c         2119 g         3366 t
ORIGIN      
        1 gttttttata aagacacgca aatgagtata aatcagctaa tttttggttt acattcctat
       61 ttttatgcat aattattctg tcattctcta atttgtgaat caatatatct gattagaaaa
      121 ctaccattga gtttttgctc cacctcatta gtccgctcaa aacgccgtcc gctaatcttg
      181 tcatagactt tctcccctct aggagcccct gcataaggac gatagaggta gcggttgatt
      241 cccgtttcgt caatatatag gactggtaaa tcttttaggt tatccaaaat atcaagaaac
      301 tcagaaactt tctcaggctt ttgttcccta aaactggtcg tcttttttaa aatgacctta
      361 atctgcttta aaactgccca tacggagggc aaagcacaat caaaacgggc cgcaatttcc
      421 cgtaaaaaag cgtctggatg agcctctaca aaggctttca attcttctaa agggatctta
      481 cgctttttga cgactcgctt tttccgctct aagttccctt gctcacgtct ttcttttccc
      541 acgtgaagag agttctgacg ccgacatcaa aaactttggc cgcctcgaca tgtctgtgcc
      601 ctcctttgat ggaatctaat gctccttgtt taaaatcagt actatatgcc atagctttat
      661 tagaccatgc ttattttaaa ctaagcaact atagatagag aaatgaaata aaatctgaat
      721 tcgaatgtga taaggagtta gaaattgaaa caataggatt cccccattat tcacacaaaa
      781 taaaaccact aaaaaacaga gcttgccagc attcttgaaa agtagtataa ttattgcatg
      841 cgcaatcatc ttgtgacgca gagactgccc gttaatggac tttcttctat attatgactc
      901 taaaaagaaa ggagacacta tgacctattt ggaaaaatgg tttgacttca atcggcgtca
      961 gaaagaaatt gaaagtctct tggaagagac cattgcccaa cagagcgagc aaagtctgac
     1021 cttgaaagag ttctacctgc tctactatct ggacttggct gaagaaaaat ctctacgcca
     1081 gattgacctg ccagataagc ttcatctgag cccgagcgca gtttctagga tggtggctcg
     1141 cttggaagct aaaaattgcg gtctactcag tcgcatgtgt tgccatcaag atagacgctc
     1201 tagttttatc tgcctgacaa atgatgggca aaagacactg gcctcgctac aaaaaactgt
     1261 cgaagaaagc ttggaagcag gtttggattt cttgatttaa gatgattttt aaaaaaagtt
     1321 gcgtgcgcaa tcatttttct tgacattctc ttttataagg agtaaaataa agttagcatt
     1381 aaacaaagga gttttaaata tgattgaaat tacctatata gatgccagca agaacgaaag
     1441 aactgtgact ttcgagtctt atgaagactt tgaacgttcg caacaagctt gccttatcgg
     1501 cgtcgcagac tactaccctg tccaaaaatt aacttacaag ggtcataatt tggactacca
     1561 tgggacttat ggagatatct tcttctatct catgaaacaa gatttaagcc aatataacta
     1621 aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc aacattcgaa caagaaacaa
     1681 aagatggttt ggtcttagta gacttctggg caacttggtg tggtccatgt cgtatgcaag
     1741 gtccaatctt ggacaaattg tctgaagaac tttcagaaga tgtcttgaaa atcgttaaaa
     1801 tggacgttga tgaaaatcca aacacagctc gtgcttttgg aatcatgtct attccaactc
     1861 ttctcttcaa aaaagacggc caagttgtca aacaagttgc aggtgttcac acagcagaac
     1921 aaatcaaggc catcattgct gaattgagct aatcaaacga gagaccaagt actttctttg
     1981 gtctcttttt tcttgccctt tgccattttt caaaaaatat gctagactat agtagattga
     2041 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
     2101 tcgatttgtc ctgttcttat ttcattttac tatataagta gaatattacg atgtttggga
     2161 tatgccatcg ctaaaaaaac tcgatttggt attttttagc tccctaatgg gagctttttg
     2221 cgtgctctga acatttccca ttttggaagg agtactatga aacatcaatc agccttggtc
     2281 gtctttagtg gtggtcaaga ttcaacaacc tgccttttct gggccatgca acactatgaa
     2341 acagtcgaag ctgtcacctt tgcctacggc caacgtcatc acctcgaaat tcaaattact
     2401 agagaaatcg ctaaggaaca gggcattcgt caccatatcc tcgatatgtc tctgctggga
     2461 caaatcactg ctcagccaga ctttgcgacg attcatattt cctacattcc tgacaagctc
     2521 tgtgtcgagt caaaatccct caaactatat ctatttagct accgaaacca cggagatttc
     2581 cacgaaaact gtatcaacac catcgggaaa gacttggtca acttgctaga ccctcgctat
     2641 ttagaagtct ggggaaaatt cactccgcgc ggtggcattt caatcgaccc ctactacaac
     2701 tacggtaagc aaggaactaa gtatgagggc ttggcagaac aacgcctctt ccaacacgac
     2761 ctttatccag agaaaattga caaccgctaa agtcatactc aatgaaaatc aaagagcaaa
     2821 ctaggaagtt agccgcaggt tgctcaaaac actgttttga ggttgcagat agaactgacg
     2881 aagtcagtaa ccatacctac ggcaaggtga agctgacgtg gtttgaagag attttcgaag
     2941 agtatcatac gaaaaagccc tgttcctcaa gatgaggagc aaggcttttt gagtttcaat
     3001 tattcttctg ttccaaggaa attttttgca acaagggctg caagaactcc accagcgatt
     3061 ggtgcaagga tgaaaatcca aacttgttga agggctgcgc cgcctaccaa gacagctggt
     3121 gccaagctac gagctgggtt tactgaaagt ccagtaatct tcaatccgac aagaatcatc
     3181 gccatcaatg acaaaccgat taccaaacca gcaatcgcgc cattgccctt gctttctgaa
     3241 gtcacagtca tgataaccaa tacaaacaag aaagttgcga tgacttcaaa caagaaacca
     3301 ccaaagacag tgacaccgtt tgccaaggca ttttcaccaa gactagcagt tgacatacct
     3361 gagttagcca agaggaagaa gacagcgcca gaagcgatga aagctccaac aacctgacca
     3421 aggatgtagt ttacaagttc tgaagatgac aaacgtttgt ttacaaacat agcaatcgaa
     3481 acagtcgggt tcaagtgagc acctgaaaca gttccgattg agtaggctgc caccacgatt
     3541 gccaaaccaa aggcaaaggc gattccaagg tgaccaaggc catcaagacc atttccaaaa
     3601 acaacagctc ctgtcccaac gaacacaagc atgaacgtac cgattaactc agcaacaaat
     3661 tttttcattt tctttctcct tttttcaaaa actagatact agtctatcaa aagtaggaaa
     3721 gggtttcaag aaaattgatt ggaaattttt tgaaaatcat agaactatta gctaatctct
     3781 agtattgaaa agactggata gcttctttca actcatcttg taaactattt ctctggtcaa
     3841 gttggacata gacttccacc agacaggatc taaagttgga aaatttgtaa aaatcctccc
     3901 tttcttctat cggaaaatca acagttttta tccaagaagc tacttgttct tgctccaact
     3961 tcccttgtaa aataggttca tagatcactc ttgctaaacg ccaatcctca tcatctgtaa
     4021 agcgaatcga cattctttta aatagttggc caagtatatc aaatacttca tgaactctgt
     4081 ttttaggaaa gtctggatga caaaccacct ctgtcagtaa atcggctcca tgtgcaaaag
     4141 cgtgaaccca accatactga cttgagaaac ctgttgtatc cttttctttt gaaagatagt
     4201 gcaagccttg atttaaaagg acattacgaa atcctgcatt taattcctga taaaaaaccg
     4261 attgctggtt ggcatctgca gacaagagat ttgcataaat aagtgcccta aaagaacgtt
     4321 caagtgttga caagcctacc ttatcaatct ctttatctaa ccctccatca gctaagacca
     4381 cctcagcaat gaaatgaaat tgctcctgtg taaatagctc ttcctgaatc cctctagcaa
     4441 agcttgtaaa aacaaggtca tcacgaattt ctggagaagg atttcccaaa tgatcaaaca
     4501 accactggat ttcttcctgg ttataatttg gtttttcttc tgctattttt cttagtaaat
     4561 cttgatacat ggtcaatacc tctacatttc tagcaactgt tcaaaaaggc agtcttaaat
     4621 gactcaatat tgaattctca attaaataca atctgatata aaatgacgta aataactatc
     4681 aataccagtt ctacagtaag ttcaaattta acatcacgac cttcaacgac atttttgaaa
     4741 atagctacaa ctaagacaaa tagaatgacg cttaacaagc ccataaacat cattctaaaa
     4801 aatttttcta ttcccctact ctcccaactc agcactatag gagataatct ggtcaactgt
     4861 gtcagacaag aattggatgg tatcacggag tggtttgtct gttgaaatat cagcaccgat
     4921 aatcatggct gactcaagtg gtgtcttgct accacctgat ttgaggagat tgagccagtc
     4981 ttcagctcca gtttcagaat gttttagatg aaggtaacca gcagtcgaga taactagtcc
     5041 tgctgagtaa gtgtaactat acaagcccat atagtagtga gcttggcgca tccaagtcag
     5101 agttgcatca tcgtcaattt caatagcatc tccccagaaa tccgtcaaaa cttccttcat
     5161 aatgctgttg agcttgcttg ctccaaaggt ctccccttct tcaatcaatg tatacacctt
     5221 acgctggaag gcggcttcca agagatgggt gataaagtta tggaagtagg tgtctgtcaa
     5281 gcgatgagcc agagcgaagc gtttttgacg tgggtcatta gactggttct ccaagtaatc
     5341 actgagtagc aattcattga aggttgacgg tgcttcaaca tagtaggtcg acatatgggc
     5401 attgaagtaa ctttgatgat tgtctgaaaa gatgaattga ccagaatgcc cgatttcatg
     5461 aatcaaggta tagacatcgc tcaaacggcc tgtccagctc atgagtacat aagggtgtac
     5521 gcgatatggg tccgccgcat aaccaccgga atccttgcca ctgttagcag caaagtccac
     5581 ccagcgctct tcttggtaac gagcaacttc ctgacaatat tcttgcccca aaggttctac
     5641 cgacttcatg accaaatcat aggcatcgtc aatagtcact tcaggattca gggcgctgtc
     5701 caagtccaat ttccagtctg caaaggtcat cttttcaaga ccatttacct tggcaacatg
     5761 cttgaggtat ctctgagcga ctggtgcaaa gtccttcatg atgaggtcaa tctggcggtc
     5821 aaacatggca cggtccactt cttgttcagc tagaagatag tcaaagacag agtcgtatcc
     5881 cttcatatca gccaagagtt tttcagactt gacctgagcc agataggctg ctgcagccgt
     5941 attttggtgc ttacgaagtc cctctgagaa ggaacggaag gatttctcac gaacctcagc
     6001 atcctcatgg ttttggtaga aattctcata ggtcacaaag ctgtttttgt aggtcttgcc
     6061 atgggcttca aagtcagcca tttcaaaatc cccagctcgc atcttagtat aaatgtcctg
     6121 cggactgtag aaaacttcac cgagatttgt caaggccttc tccacatctg cccctaagta
     6181 gtgggctttt ttgattttag cctgacgaat ggcagctgtt aaatgtggca atttacccaa
     6241 acggtccaag acttcctcat ctgctgccac caaggcatcg tcaaagaagg tcaaggctac
     6301 gctggcatct gtttcaaatt ccatcccagc ttgggcaata ttggcaaatt cgtcattgct
     6361 atagtccgtc gtctgaggca taaaaccata gttgccaata tggctcatct gaatgtagat
     6421 ctgttccaat tccgcaaagg ccttctcgaa atcctcaaaa gtgtgaagat tgcccttgta
     6481 atcacggcta aactggttga tgtcttcgcg agctttctcg attgcacgca agaaatcctc
     6541 acggtcttgg tatagggctg ttaagtccca gagttccttc tctggaaatt ctgaacggtg
     6601 tttttgttcc attttcttcc tcttatttct ctaattctac taaaacacta agggctgata
     6661 aagcgtaaag cggtgctgtt tctgctcgca aaatacgagg acctaggcct gccaaaacgg
     6721 ctcctttagc ttcaaaactt tcgatttctg caggtgagag accgccttct ggaccaaaga
     6781 taaagagcag tttggctcct gtttcaagac cagtgactgc ttgcagaagc gcagcggctt
     6841 ctccttcttt agctgattct tcataggcta ctatgataga gtcaaactgg tccagctgag
     6901 ctagaaaatc tgcttttttc tcgaaaagtt taatacttgg tacaatatta cgcttgcttt
     6961 gctcggctgc tccaagggca attttttcta gtttttcaac ttttttaccc aatttcttgc
     7021 catcccactt ggcaactgac cagtctgcag gaaaggccca gatttggcta gcccccagtt
     7081 cggttacttt ttgagcgatg aactccagct tgtctccctt gggaaatcca gatgcgatgg
     7141 tcacttggac tggtagttcc acattgtcat ttaattcttg gaccaactca aactgacgat
     7201 tttccatatc cagcacgcgc gccaagcgct tgatgccatc atcaaagact aaggtaacct
     7261 catcctcttc tttcaagcgc ataacctgaa acatatgctt gctggtttcc ctgtcctcga
     7321 tggtgacagg agagactgca ctccccttga caaaatactg ttgcatgcta gcctccaatc
     7381 acacctgaaa tatccttggt cttcttgaag acgcaggcat tccattcccc ttgaatcata
     7441 tgggtttcaa ggaaaaatcc agctgactca gccgactggc gcaccatgtc ccacttgtcc
     7501 ttgataatgc cactcatgat gaggtagcct tcatccttta ccaagcgata agcatcctcc
     7561 gtcagatgaa tgagaatatc cgccaagata ttagccacga tgacatctgc ttcaatctca
     7621 actcccttaa gcaagtctcc tgctgctaca tggatatttt ccataccagt gttgagctca
     7681 atattttcct gagcgacacg aaccgccaca tcatccaagt cataggcgaa aatctccttg
     7741 gcacctagga gtgagcttgc aatagaaaga acccctgaac cagtccctac atctagcact
     7801 gtttcgccac cacgaagaac ctgttccaag gcaaagaggc tcatcttggt tgttgggtgg
     7861 gtccctgtcc caaaggccat accaggatcc agcttgataa tcatttcccc cgcagtcgcc
     7921 tcatagtctg tccaaaaggg aacgatggtc aaatcatgag tgatacgagc tggctcatag
     7981 tatttcttcc agttgtctgc ccagtcttcc tcagccaagg cagtcgtacc tatttttaac
     8041 tctcccaaat ccataaaatc tgtcaattct gctagacgag cctgcaaatc cgcctcaacc
     8101 actgtcacat ccaccgtgtc agggtagtag gctgtcacta cgatttcttc ttgctgctcc
     8161 acctctggga aaatctctcc aaagcggtcc acatttccca catagtccat actgtcttcg
     8221 attgcgactc cttgcgctcc cagctcaatc aagagattgg aaaccaactc ctctccctca
     8281 cgcttcactg taacttttaa ctcttgccat gtttccatta ttaataccaa gcccgtaaaa
     8341 cacaaaacca aaataggaaa ttctctgaag acgcttgtgt ctaagagaag tttatctttt
     8401 tggcacagtg tttagggcgg gttcagttta gaaatgtaac tgaaccatcc tttctaatca
     8461 cttactttta aataatcttt taatctctct tgcaactgag gcacaacttg actggaacta
     8521 agaaattcct caacattcat cagctgatag ccctgtcctt catctccaaa tacgatactg
     8581 tcaaactggt tctgtgtcaa ctgaccaact agaaaaacgg actgtttgtc tgcaaaaagc
     8641 atacttgggt aaatcttact ccaaagcaga caatcttcag tcagatgaat gcccagttct
     8701 tcataaactt cacgcgctac acactcaaaa ggactttcat caccttcacg tccaccacct
     8761 ggcagttccc acatattggc ccagggaatg cttgccttat catcgcgtaa gatagtcaaa
     8821 agcttatccc cacaaaacaa agcaatctta cagcctagga aatcagaaat ttctagttcc
     8881 atcttcagtt ccttctaaca tttccttttc cagctctgct aacaagtttt cataatagcg
     8941 tttctcgtcc ctcaacattc gactactatc cattttctgt ctagcaatct tgagagcctt
     9001 acgagttcga tctacatctt tcttcacctt taattgatac caggcttgta tcacttgaag
     9061 attggacagt ttgagagaca gaaacgattt gacctgtcga atactagcat attgctccgc
     9121 ttgctcaaaa tctccttcca acaaggcgat atgaagcagg gatagttggg caactgtctg
     9181 catcatcgga gtagttgtcc tctcaagtaa tgcttgaaac tgctgtttag ctacttcttc
     9241 cttcccttcc aaaatggaaa cttcaccttg catacctaat acaccatccg caaaactccc
     9301 tcgtgcatcc tcaggaactg cttgaacaaa gtctttcaaa tcatattctt gaggaaccag
     9361 caaagtttga gcagaatgtc tcaataccag gtaggcgtat ttggtatttt cagggtgttg
     9421 tagtaattcc caaatttttg ctccatcggt gatgtcgact ggcaaaatgt tatttaggaa
     9481 gaaagataaa ttaagaaaaa tccaagtccc tgcaaaatac cagcttcttg tcaaaaatcc
     9541 aaacactatc gccaataata tcaagccgag atgaaccatc aagcctcctg aaagcatcag
     9601 gatgattctt tgatcgcttt catcctcttt taaaccaatg tattgagcac caacattttt
     9661 cagaatggct gttctactaa gatgaaacct gcctgacttt ttggtcaaaa taaaatgtcc
     9721 taatccaaaa gccaccagcc gatagcctgt caagtagcca caaaaagcat gacccagctc
     9781 atgaagaata aagattaaat acatgcttag aagagcgaag gcataaccaa aagtaaaggc
     9841 taaaactgcg gaatacccca actctgcaaa tgcgattgtt ccacaagcaa aagctagcat
     9901 aataaagaca acagctagca cataaaccaa ataagtccca attttcttca taacacctcc
     9961 aaccaactcc tagtatcttg gataagggta aaattctccc tcttccaagc caacttttcc
    10021 ttcttcaaag acttcttggt tccattccat gacaaattcc tctgcttctg ggtcttccaa
    10081 aaagtccatg aggacatcta gcccaacctc agcagtatct ttaaggaaaa gcgcaaaata
    10141 agctaaaaat tcacgggaaa atcctttttt aggcaggtaa ggaataacag tcaaatagtc
    10201 ttcctcattg actgttgact tggcaggatt gtagaaaagg accgcttcct caaaaagaat
    10261 gtcatctgat gaaacctctc cgtcttcatc caccatctcc acacctgcag cattttgcgc
    10321 ttccaataga aaactcactt ctaccgcatg gttgcgtttg tcccaactaa tctcaaagtc
    10381 aaagggaaag ttcttgtcca actcttcctc taaaatatct aaaaatccgt atgttgccat
    10441 tttgtcctct ttctatgcga ctctttaatc gccccgattg ctcggaaata tgctaaaata
    10501 gatactacca tcttaccaca aaattatttt atgtcctaat tataccatat tacctcattt
    10561 aaacccttgg tatcagtgat tttcttaaaa gtctgatttc ttcatttctc ataaaaatca
    10621 atataaaaag ccctcgaaag ggctaataaa tctataaaat caataggcga gtaactagca
    10681 caagtggacg tgctttttta ttgactatta ccacgatacc acgcttaatc ttaggcttga
    10741 actttcttat ctgcaatagc gtctgtcaaa gtctgagaaa agttaagtcc catttctcgt
    10801 cccaacttat ctgcccattt tggtatggtc aaagtctttt taatgggttc ctgacttcct
    10861 aggtattctg atacatcaac agataccata gaaataaaag atttatcaag gtcataggtt
    10921 gacacgaaat cttcatcatc tttaaaagga tcattatcaa ttaaagacaa gctattgata
    10981 tctgatggct gaggtaactc tccatcactc tctatcaaat ctgcaacagt tatccctagc
    11041 cactccgacc ccatagccaa agcctcagaa atcccctctc cttgtgtagc tgagtattca
    11101 aaatctggga aatggacaaa ataagtcgct tctgttccgt ctgtgtcgtc ataataaaat
    11161 aaagctggat acgtaactaa catttcacta cctccatatc aaaaagcagg ggctgaattt
    11221 tacaacccag cttgctttct tatccctctt tcagtgtact tattcagctt accatgaagg
    11281 attgtgatag gtctttcccc ttacttttcc attttaatat gggagccttt accgcctcta
    11341 gtctttatcc aaccatgggc cgtaaggagt ttaaccatct ctttttgtgt cataggcata
    11401 gcgcttttac ctcctgacaa caccattata acacgtgtta cacgtattgt aaaggagtga
    11461 tacttattat tctattatac ataaaagccc ctagatgtgg ttctaaggga agccaattta
    11521 ttcataccta tttttctaat gagtagtaaa aactgcttct ttatcgagca attcatcatc
    11581 tgtatagtca attgtaaaag tatctcgatc taagacagat tgaggcggag ttgaatgaat
    11641 cataggaaca ctgcgtactc tatatttttt atctccaatt tttacaaact
//
LOCUS       DBEJNA010000049        10853 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEJNA010000049 DBEJNA010000000
VERSION     DBEJNA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.49"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(212..1636)
                     /locus_tag="ACL3JB_001860"
     CDS             complement(212..1636)
                     /locus_tag="ACL3JB_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0686536.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHTAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2181..4460)
                     /gene="pulA"
                     /locus_tag="ACL3JB_001861"
     CDS             complement(2181..4460)
                     /gene="pulA"
                     /locus_tag="ACL3JB_001861"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0686537.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAAFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4572..6530)
                     /gene="ligA"
                     /locus_tag="ACL3JB_001862"
     CDS             complement(4572..6530)
                     /gene="ligA"
                     /locus_tag="ACL3JB_001862"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0686538.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6623..7801)
                     /locus_tag="ACL3JB_001863"
     CDS             complement(6623..7801)
                     /locus_tag="ACL3JB_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0686539.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7881..8744)
                     /locus_tag="ACL3JB_001864"
     CDS             complement(7881..8744)
                     /locus_tag="ACL3JB_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0686540.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8747..10648)
                     /locus_tag="ACL3JB_001865"
     CDS             complement(8747..10648)
                     /locus_tag="ACL3JB_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0686541.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3277 a         2380 c         1922 g         3274 t
ORIGIN      
        1 acttcaatgt actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt
       61 caaatcgatt tctagcaatg ttttagaagt agagctgtac tattctagtt tcaatatact
      121 ataataccaa aaagttcgta ttttttctat aattattatt attttatagc aaaaaaataa
      181 aaccaggaaa acaatttcct ggttttacac gttatttcac atcaaaaaca atggatttga
      241 catttgtcat cgcttcaatg ctatatttaa ttccttgcac tccagctcca gaacctttga
      301 caccaaggaa tgggaaatta tctggaccac gctgggtttt attattaatg tggactgtac
      361 ctacttcaag tttttcagca atttcaaagg cttttttgaa atcatttgta aagactgatg
      421 attgaaggcc gaattcagat tcgttggcaa aggcaatagc ttcctctaca ctagccacac
      481 gaatgattgg taaaacagga ccaaatggct cttcccatgc cactttcata tcttttgtaa
      541 cttggtcaaa aagcactggc cagaggagat tgccctcacg tttgattggt gtaagagcct
      601 gagcctcttt ttcttgtgca tcctcaatca agccccaaat gaagtcggct gaagcattgt
      661 caataacagg tgtaatatca gcattgtcaa atggatcacc aactgttaat ttagaaactt
      721 cttcctgaag caaagtagct aatttatctg ctacactttc gagaacaatg acacgtttaa
      781 tggccgtgca acgttgtcct gagtagctaa aggctcccgc aacaatttgc ttggcagtat
      841 gttccaaatc tgcatcttct agtacaagag ctgcatcttt cccaccaagt tccaacatga
      901 taggacgcat accagctaaa cgaccaatac gttctccaat aggagttgaa cctgtaaagt
      961 tgatgaaatt gacttctttg tgctcaatga tataatcccc aatttctgaa ccacgacctg
     1021 taatggtgtt gaaaacacct gccggaatcc ctgcttcttc aaatgcttta gccaacaaga
     1081 gtccagaaat ggaaccttgt gttggtggct taaacatgac cacattccct gcaatcaagg
     1141 caggtgcaat tttagaagca gataaattaa ctggataatt aaaaggagca atcgctagca
     1201 cgataccaac tggttcacga cggacaacag ccagtttgtt tttacttgct gcctcaaaac
     1261 caccaccttc cattgcttgt ccagtgatac ggagaccttc ctcagcagca taacgaatca
     1321 agtctgctgt acgcactact tctccaattg ctgctttaat cccttttgct acttctttgg
     1381 caaggatagt accaattttt tccttatcgc gttctaaaat agctgctgtt ttatgcaaat
     1441 aagccgcacg ttcaattgct gataaagctc gccatgctgg cagggctgca cgcgcagctt
     1501 gcatagcctc atcagcttca gtctgagtca tggctggaac tgtacccaat tcttcttgat
     1561 tgattggtga ataaatcgta atttcttgtt cagatgattt ccattttcca tttactaaat
     1621 tctgatatct tgtcaaattc ttgtcctcct gaaaatgatt aagatatatt ttaccaaatt
     1681 ttcagaaaat cacaaccctt tttgcaaaat ttttgagatt attttcacaa tcttgatttt
     1741 tcaaagtata ctcaataaaa attaaaaaaa tccactacgt caaggcgagg ctaatgtggt
     1801 ttgaagaaat tttcgaagag cgtgaatgag tatcatctat agtaaaataa aaaaactgaa
     1861 caatttggtt ggggacagcc aaaccaattt ctcacaatgt ttcagaaaca agggtgtgct
     1921 attccaattt cagcctacta taactgtcat agattgctga aacaaagtct agataaaagt
     1981 cttcataata aaaagacctc ctatcaagtg ttcaaaaact ttgataggag gtcttgtttt
     2041 gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt agccaggttc tttctattct
     2101 ttcaatttca atgaatggat tttttactaa tactcataac tgggaatttg tctgtgtaaa
     2161 aatagcgaga tagatggtat ttataaaaca ctcaagacag ctagactaat atcatttaaa
     2221 acattatctt cttttgagcg actgttggtt accaacatag ctaaatttcc tgcattttca
     2281 aattgatagg gttctgattt agcattcaca accaccaaga ggtgttcttt gccgtgaact
     2341 tcatagataa ggtagccgct atgttcaatc gcagaatgca caaagacatg atggtaaatt
     2401 tcatcatagc tagagtaaga aaaggcacca gtttttgtct tcaatcggat gacttgacgg
     2461 ataaactcaa tactgtcttg acgctcatta atcaagttcc agttcacttg gttcacactg
     2521 tcaggagcat tatagctatt catcgcacgc tctctatcat catgggtcaa ctcaccattt
     2581 tcaccagtcg caaccagttt ggtacgacca aattcttgac cgatttccat aaaggccatc
     2641 ccctgcatga gcagattcat ggctgtggca gtttcgacct tgcgcatgat ttgctctgaa
     2701 ctttggtctg gatgaagggt tgccaataaa tcgtgaagat tgtaattgtc atgggcttct
     2761 acatagttaa gcacctgatt tggatgtgta tagcttccta attcacgact tcctaggatt
     2821 gctttagcta gaattggctc tgtcgcagca ccactgacaa aacctgactt gatagcacca
     2881 taaacttctc cccctttgac agcatcgcgc tgattgtcat taaagaaacc aatatttggc
     2941 atctggtagg cattgtcctt cttggcctta tcataagggg caagacctgt tcccatatcc
     3001 catccttctc catagaggat aatgttggag tcgatttcat ccaagctttg acgaatcatc
     3061 tgcatggtct tgacatcatg aatccccatc aagtcaaaac ggaagccgtc aatattatat
     3121 tcctgcaccc agtatagaag agaatcaatc atatacttgc gaaacatttc gtgttcactg
     3181 gctgtttcat ttccaacacc cgttccattc tggaaggtac catctggatt catacgataa
     3241 tagtaatcag ggactgttgt ttggaatgct gcatcaacaa ctgagaaggt atggttatag
     3301 actacatcca taatgactcc aatacccgca tcgtgataag cttgaaccat caccttcaaa
     3361 tcacgaatga cctgagctgg atcatctgga ttagttgaaa aactagtttc tggcgcgtta
     3421 tagttttgtg gatcataacc ccagttgtag gttacatttc catcctcatc gtattcttta
     3481 tgacggtctg caattggttg caattgaaca taattgtagc ccagcttctt gatgtaatca
     3541 aaagcagttg actggccgta ttggttaact gttccagcct gagcagcacc caagaaagtt
     3601 cctcgaagat gttcatctac acccgatgta ggtgatttag tcaaatcacg aatatgcatt
     3661 tcacagataa ctgccttaca tggattttcc aagcgccaag tagcctccga accgtgctta
     3721 acctcgaagt tttcaacttg cttttctaca tggctcagaa tagctgaacg tttgccatca
     3781 gggctggtcg cgattgtata aggatcacgt gtcagtgttt ggtgatgagg gaattggact
     3841 tgatactgat aagtcttacc taccaaatct tcttcaacat ccaaactcca gacaccgatt
     3901 gtattgtcct tatgattata agagtagcta ttgcctcttt tcatctcaaa agtcttccaa
     3961 acgggtgcat cattagcagc tgattcataa acgacaactt gcacttctgt cgctgtaggt
     4021 gaccagaggg aaaaatgagc ctgattgtcc tctacacggc aacccaattc tccttggtaa
     4081 ccccaatgat gatcaaaact agcactgtta atggccttat caaaggcaaa aggattttga
     4141 tttttataga aaggactggc aatagcagga ttttcagagt aataaatcct atcatcgcct
     4201 tccaaaatcc agacctctgt taatagggga tagtgattaa aacggataga atattcttta
     4261 ctagtttgac ctgtatgaac cacaaaattc aagctttcta taacatgtga acttgggtgt
     4321 tcaaagctaa ataaagctcc aaaataatct tctttgtagg ttagcaaatc aattcgttga
     4381 tcctgacttt ttacaaagga gcaagtgtca tattctccat tcttacgatg gtaatgaatg
     4441 cgcatagggt agttatacat tttttatttt tcctttttac tttgtttcta tttcactaat
     4501 aaatttttgt caatctcgtc tcaattaaca gacatagtca tattctctaa actctgtttt
     4561 taaacgatcc attacaaact ttctagccat gcctcatctc tgacctggat accaagttct
     4621 tgtgcttttt gcagtttact tccagcgtct gcacctacca cgacgaggtc ggtcttttta
     4681 gaaacactac ctgtcacttt ggcacccaga ctttcgagtt tacttttagc ttctgagcgc
     4741 ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac ctgacaaggc cgcatccgct
     4801 actaccgtct gtcctttata gtccagattg accccagttt ctttcaattc tctgagcaga
     4861 atttcagagc cttctgtcgc aaaataagtc tgaagacttt tggcaatcac gccacctaga
     4921 ctttcaatac tagccacttc ctctgaatct gcctgagaca gattttcaat tgaatggaaa
     4981 tattgaagta aaagctgact aaccttgctt ccgacatgac gaattcccaa accaaataag
     5041 agcttctcgg cagaattttc ctttgatgct tggatagcct gatacagttt agcagcggac
     5101 ttttccttaa ccccctctaa aaggaggaaa tcctcttctt gcaaacgata aatatccgcc
     5161 acatccttga ctaaattagc agcaaaaagc ttctcaacaa tagatggacc aaggcctgta
     5221 atattcatag catcacgaga agcaaagtga atcaagcctt ccatgatttg agcagggcaa
     5281 cgcggattga tacaacgtag ggccacttca tcttcaaagt gcaacaagtc agagttacaa
     5341 cttggacagt ttgtagggat atctagtttt tcttcagaaa cccgtttgga ctctaccaca
     5401 cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa tgaccgtatc gtcttttcgg
     5461 atatcttttt cagcaatata atctacattg tgcagggtcg cacggctaac agtcgtaccg
     5521 gcaagttgta ctggtgttag attagcagtt ggagttacaa caccggtacg gccaactgtc
     5581 cagtcaactg ataagagttg agcttctttt tcttcggcag ggaacttgta ggctactgcc
     5641 cactttggag ccttaactgt aaaaccaagt tcttcttgac ttgctaggtc gttgaccttg
     5701 attaccactc catcaatatc gtaaggcaga ttttcccgtt cctgtcctac ttcttggata
     5761 aaattccaga tttcatctat gttttcagcc aagattcgct taggattgac cacaaaacct
     5821 agttgttcta ggtacttcaa acccttttct tggctatcac gagttgaagg gctggcttct
     5881 tgatagagaa acgttgcaag attacgcttg gcaactactg ctgtatccaa ctgacgcaga
     5941 gttcctgctg ccgcattacg aggattagca aattcaggct ctccattttc ttggcgcact
     6001 tggttaactt ggtcaaagga agcgcgtggc atgtaacatt ccccacgaac tgtgatatct
     6061 agttcttctg gcaaagtcaa agggatgtcc ttaacacgct tgaggttttc tgtgatattt
     6121 tcaccaattg aaccatctcc acgtgttacc ccagcaacca aaatcccctt ttcataagtc
     6181 agcgagatag ataagccatc gattttcagc tcacaaatat aggtcggatg agccacttcc
     6241 ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg aaaaagcatc ctgcaaacta
     6301 taaagaggat actgatgact gtatttttca aaaccatcta aaaccttgcc accaacacga
     6361 tgagtcggac tgtctgctag cacttgctct ggataagcag tttctaactc gaccaactca
     6421 cggtaaaggc ggtcatactc actgtctgca accgagggat tatcgctggt atagtactca
     6481 gtcgcatagc gattgagcaa agcgactaac tcattcattc ttttattcat aagaccattt
     6541 taccataaaa caagccctcc tcacaaacga gaagggcgga aaaaacactt agtttgaaat
     6601 tatttttgaa actcaagcaa ccttatatca atttttcaaa atgagttcga acataaataa
     6661 acgatataca agacaagatg ataacaccac ttccaattat caggaaagaa gagagatgta
     6721 cacttggcaa gactgtcata aatccttttg caataggcat aaatagaata gctaaggtaa
     6781 aaattgtact cagtactctt ccaagaaatt cgctctcaac cttggtttgt acttgagtaa
     6841 aaaagtgaat attaaaaatc gtcataaaca attcacaaac taaatttcca gaaaaggaaa
     6901 gaaaagttgg aagtggtaat cccatcataa aaactccgac acctgtcaaa gccagtaaaa
     6961 tcaaaagatt ataaatatta gctttaattt tactagctag aagagcccca atgatggaac
     7021 caatagcccc catagttaaa atacttgcat aggctccttc tgacccgtaa agctgattcg
     7081 aaaagggaag tagaaattca aaagctgcaa aaaagaaatt aacgctggaa gctaccagca
     7141 aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa cccatccttg atatctacaa
     7201 aaatatctct cccagtaaaa gcctttttct cttgaacttt tgcttcctct tttggaagga
     7261 aagccactag aacaaaagca atgaaaaaag tcagcgagtc tagcagtagc gtcatattga
     7321 gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga gctaacacct acaacctgca
     7381 aaaccagctc taagcgagaa ttatagatca caatctcatc tttctccacc acttcagtta
     7441 tgatagcttt attggctgtg cgagaaaagg caaaagcaat agcctgcaca atgttagcaa
     7501 caatcaaagc gccaatcatc cagctatcat tccttatgaa agaaatagcc agacaaagaa
     7561 tcccacaaac aagatctgcc gtcattaaaa tcttacgacg agaaaaacgg tctgaaataa
     7621 ctccgccaaa gggattgacg agaatagatg tgacgagctc agaaatctga tacattccta
     7681 aaactgtctg tcctatagtc cccatagaag ccaaccagac actatttcca taatcataga
     7741 gcatatttcc cattttattg atagccccac ggctaatcaa ctgcactgca tagcgattca
     7801 tattaaagct cctctcaaat tttgaaacta ttgtatcaaa accgaaagga gctttttatt
     7861 ttttccctta tttgggaaaa ttaacttttg acaaattttt cgtagtgttc ctgataatag
     7921 gctacttgct ctggaagacc taacacatca aaaatatgca tggcctcttg catctgctta
     7981 cagccttctt tacactgtcc tttttgatat aaggcaaaac cttttaaata atggaaaaca
     8041 ttacgctcat aaagcttaat acctttgtca ataatcttct ctgtataagc ctcaaaatag
     8101 ttggcattat aaaaagaaga atgctctaaa caatgctggt aacaattgag ggccaaaatc
     8161 aaaactaatc tcttatggcg actaatctct tggtaaaatt cctccctctc cataacttct
     8221 ctaccaatcc gagtgacata gtctacatcg tagaaactat agaggttacc gaaaagaatc
     8281 aactcataca tggtccattc ttctgttttg aagagataat ctgctacctt atccaaatca
     8341 tcctgcttca tatcataagt cgcatctctt tgacaaatca gaccttgtag caaaatccag
     8401 ttcagctcaa aataaaggga agtcgtcgaa ctcttagact tttcaagttg ttctctttga
     8461 agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg ggataatctg tgccatcata
     8521 gacacatgtt catgattatg aaaattcctt gccttatcca tgaaattttc gattgttaca
     8581 tgaatgttat ccaaaatctc aaagaaacgg gagactgcca ggtcagactc cccaagctca
     8641 aagcgagata actgagaggt agagcaggat tcgcctgctg cttcctttaa agaataattt
     8701 ccacttgttc gaaattcacg aaatactttt ccaagatgtt ccatctttac acctgatctg
     8761 ataattcttc ccactcaagc atagcttctt cctgacgatg gctgattttg tccagctcag
     8821 cctgtaattc catgagtttg tcggcatcgt ttgtttccaa catttgttca gaaatggctt
     8881 ggctttgact ttctagctct tcaatttcag cttctagact ttcgatttgt cgcatgagtt
     8941 tgcgaacttc tttttgactt tctttctggg cctgatagtc attgactgga cttgcttcct
     9001 ttgcttgatt gctagttgaa gcttcctcag tctgactcat ttctgctgtt gctttcttct
     9061 caacatagta gtcgtaatct ccaaggtaga gagttgaacc attctcagac aattccaaaa
     9121 catgagttgc cacacgattg ataaagtaac gatcatgact gacaaaaagc aaggtaccat
     9181 caaagtcaat caaggcattt tctagcactt ccttactatc aatatccaag tggttggtcg
     9241 gctcatccag aatcaaaaag ttattgtttt ccatagacaa tttagctaaa agcaaacgag
     9301 ctttttcgcc accagatagc atgccgactg attttttaac atcatctcct gagaaaagga
     9361 aggccccaag acggttgcgg atttcaactt ctggtgtcag tttgaaatca ttccagagtt
     9421 catccagcac cgtattactt ggtgtcagct tgctttgggt ttggtcatag taaccaacct
     9481 caacattagc gccaaagcgc ttttcacctt tgataaaagg aatctggtcc acaatagact
     9541 tgataaaggt tgacttgccg ataccatttg gaccaacgat agcgacagca ttcatcttac
     9601 gaagatctag gttgataggt tgtgacaaaa cttccccgtc ataaccaata gcagtatttt
     9661 caacagtcaa aacaacattg cccgacgttt tttcagactg gaaggtcatg ttggctgctt
     9721 tcttgccagc ttcaggcttg tccaaacgct ccattttttc tagttgttta cggcgagatt
     9781 gagcacgttt ggtcgttgaa gcacgaacta gattgcgatt gacaaagtct tccagagcag
     9841 cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt agctagcttt tgctccttca
     9901 actcaacaaa acgagagtaa ttccccacat agcgatccaa ggaatgcttg gtcaaatcta
     9961 gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg gctgacgata atgagggcac
    10021 cgctatagtt taccaagtaa ttctctagcc aggagatggt ttcaatatcc aagtggttag
    10081 ttggctcgtc caagaccaag agattgggct tttcaaggag cattttagct agagccaaac
    10141 gagtattttg accaccagaa agctcagcaa ttttcatctg ccacatagac tcgtcaaact
    10201 tgaatccatt caaaatcgct cgaatatcag cttcataggt aaagccacct gcttggcgaa
    10261 aattttcaga taagcggtca taatctgaca tcagtttatc caaatcctca ccagactttt
    10321 cacccatctc cagctccatc tgacgcagtt gtttatctgt ccgacgtaag tcatcaaaga
    10381 catgaagcat ctcatcatag atggtatttt cagactcaaa acggctatct tgagctaggt
    10441 aagacagaga aatatctttt ttcttattga tttctccact agttggctcc tcttctccaa
    10501 ctaaaatctt caaaagagta gacttacctg caccattttt cccaacaagg gcaatccgat
    10561 ctcgttcatc aacctgcagg ttgatattat cgaaaagaac ctctcctgca aaagaacgtt
    10621 caattttatt agcttgtaaa ataatcatac aagtagtata gcatgtttcc ctaaggcatt
    10681 caagataatc gtaagtcttt tagtacaact tttataacat aaaataaact aaattatgta
    10741 tattttatat tagattcctt cactatcttg ttggattttc taaccagcta atcttgtttc
    10801 aaatagttat cgcacaagcc tattatttaa ttcttttcat tatttacgta cgc
//
LOCUS       DBEJNA010000050        10565 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEJNA010000050 DBEJNA010000000
VERSION     DBEJNA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.50"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            822..1193
                     /locus_tag="ACL3JB_001866"
     CDS             822..1193
                     /locus_tag="ACL3JB_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HGR0686542.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1201..1413
                     /locus_tag="ACL3JB_001867"
     CDS             1201..1413
                     /locus_tag="ACL3JB_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686543.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            1787..1912
                     /locus_tag="ACL3JB_001868"
     CDS             1787..1912
                     /locus_tag="ACL3JB_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686544.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            1893..2139
                     /locus_tag="ACL3JB_001869"
                     /pseudo
     CDS             1893..2139
                     /locus_tag="ACL3JB_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2296..3354
                     /locus_tag="ACL3JB_001870"
     CDS             2296..3354
                     /locus_tag="ACL3JB_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686545.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            3669..4646
                     /locus_tag="ACL3JB_001871"
     CDS             3669..4646
                     /locus_tag="ACL3JB_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686546.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            5023..5397
                     /locus_tag="ACL3JB_001872"
     CDS             5023..5397
                     /locus_tag="ACL3JB_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR0686547.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            5404..5586
                     /locus_tag="ACL3JB_001873"
     CDS             5404..5586
                     /locus_tag="ACL3JB_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686548.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            5605..6507
                     /locus_tag="ACL3JB_001874"
     CDS             5605..6507
                     /locus_tag="ACL3JB_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686549.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            6563..6802
                     /locus_tag="ACL3JB_001875"
     CDS             6563..6802
                     /locus_tag="ACL3JB_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0686550.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINGNPYPWDGFISATVR"
     gene            6799..7527
                     /locus_tag="ACL3JB_001876"
     CDS             6799..7527
                     /locus_tag="ACL3JB_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686551.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            8006..8203
                     /locus_tag="ACL3JB_001877"
     CDS             8006..8203
                     /locus_tag="ACL3JB_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686552.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            8660..8899
                     /locus_tag="ACL3JB_001878"
     CDS             8660..8899
                     /locus_tag="ACL3JB_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686553.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            8884..9162
                     /locus_tag="ACL3JB_001879"
     CDS             8884..9162
                     /locus_tag="ACL3JB_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686554.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            9448..>10565
                     /locus_tag="ACL3JB_001880"
     CDS             9448..>10565
                     /locus_tag="ACL3JB_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HGR0686555.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYDEDQKKTEDKAKAVKKVDEELQKANLE
                     LQKAHVKYQKAQRELSESPDRRKSAARKKLADALSYIGEVELKQKEAEANFNTEQAKV
                     IPKETELAVTKQKAEEAKKEAEVAKKKFDKAAQEVEVAKKEVEAKELEIEKLQDEIST
                     LEQEVATAQHQVDNLKKLLAGVDPDDTEAIEAKLKKGEAELNAKQAELAKKQTELEKL
                     LDSLDPEGKTQDELDKEAAEAELDKKADELQNKVADLEKEISNLEILLGGADPEDDTA
                     ALQNKLATKKAEFEKTQKELDAALNELGPDGDEEETPAP"
BASE COUNT         3611 a         1348 c         1950 g         3656 t
ORIGIN      
        1 aatagaattg tcattcgcaa gtcatataaa tgttgatagt ttttatagac ttctaagcgt
       61 tgcaagattt tctcggatta ttgacaaata aacagacatt ctgatagacg attgctctag
      121 cggcttagtg taaactttac aaatttggct tgtaattttt ttataaaatt cactttagtt
      181 acttgacagt tattatattt tcgctcataa tatagataaa aggatgggat aggagtttaa
      241 aaatttgaaa gcgctatcca taatcgtaac gcataatttt ctccttttcg tgaaaaaagt
      301 taacgtaatt ttgaaatgag cttaataaga ggtactatgt aggtagaaaa taaagatagg
      361 agaaaaagta tgaataaaaa aatattttgt attctagtat gtattatatc attgattagt
      421 ctagctatag tctttccatg gggctggtcg atataatgta agggagcttg agttgttagt
      481 ggaggataaa atgttaagag taatagtagt tattcaatct ttagtaataa tactgcttgc
      541 tgttgcttta ttattatctc ggaaaaactt tgattcgtta aatgttgttc ttataatgat
      601 gatcgtatca caattgttgt tattagtata tttgataaaa tcagggaatc agtgattagc
      661 tgttatttga attaagtaaa ctgttaagct tcaagcagta actggtttta aatatttaaa
      721 ataagataaa ggaaggaagt ctaatttagg taactaaaca aagcctgcga tcacttgtta
      781 ggaaaccatc ctaagcatgc ttaataaaaa ggagaaaaca aatggaactt gtattaccaa
      841 ataattatgt tgtgattgat gaagaagaga tgatgtacct tgatgggggg gctatatata
      901 tacccaggtg ggcaattaca ggagccatta ctggtgcagc atatgcagca ttagcagcag
      961 caggaggtgg aggccttcaa ctagttcttg catcttatgg attacgctcc gcactggtag
     1021 ctgggattgt taaaggttta ggagtattag gaattcatat tggaaatgct tttgcaaata
     1081 ctgttattag aagtattgca tctgctggaa ttggtgctgg agctgattgg atttttacca
     1141 atattattga tggctgggat gggcgacgtg ataatcaatt gagaataggt taataatctt
     1201 atgttgattg ttttaatttc agttattgtt gcattcctgt atcataaaat tacagagtat
     1261 gtcaacaaca ggaaaattga tattgttatt tttctatcat tgctgatttc tcattttatt
     1321 tggaattact attttttacc aattgaaata ttgatagcaa tcagtggagc aaatttacta
     1381 ttaagttttt taaaaaaatt acagactaaa taatattaat ctgtgtaata cagtagctcg
     1441 gtcattagat tctattgaag atataaatta aaaatgaggc tgggaaaaaa ctcaatttga
     1501 aaatgagatt gagtaaatct ttctatctat ataacgtata tcatcaatat ttttgaacac
     1561 ctgataatat gcatttttct tattttaaag attttttgcc tttcttcatt tcttgaatga
     1621 attggagaga tgactttatt taggtgtttg acattactat agataggatt tagcagtact
     1681 aatatgaact catattatag gtgcagactt aaattttgga agcaagctaa aggatatctt
     1741 atctaggtaa ctaagtgcta taacaagata tattggtgga gttagtatgg caactattac
     1801 taatgctctt aatattgcgg ctactgttgc tgaagtcttc tcattaggag gagccattgc
     1861 atatggttta gatatcgtag acggtaaatt tgatgggtat ttatgggcgt aaaactatag
     1921 ctatgaaaca ttttttttgc aggaattggt gaaattcatt ttttgttatt tttattatat
     1981 ctaagcatgt ctgctagtcc aattattgga ctagtgattg gatatactaa aataaatcta
     2041 ataaattcta ttattatagc tcttggtatg atattggcat taattttggt attatcaaga
     2101 gtgtatagaa aatattttta tagagacgat gatgactaaa gtttttatca ataatttggg
     2161 ctccttgtca actgtagtgg gttgaataaa agctaacgtc tggggaaggg tttaaagctt
     2221 tgctttatca aatattgact tacagagttg ctctattgta ttgatgtatt cttagtaaat
     2281 aatatggtgt tttaaatgaa agatgatcag aaatatttat tagcgggact ttattcgctt
     2341 ctagttgcaa tattttattt tccattgatt gagtccaagg ggatttttgt aagtatattg
     2401 atggcggttt tacttttata tttaatatac ttcattgcaa cagtcattca tattgtgata
     2461 attaagttta taagaaaaaa atcttttaag tatttggttc tatatccatt tacttacgat
     2521 gggagctgga gatttcaacc tataaactta ctctactttc cagaaatggt gagagatgtc
     2581 attccgatta atttagttca agaatattgc caaggacaac cttacggact gttaaaaaag
     2641 atgctgaaaa gaattcgatt gtcacgagag atatctttac tcctggctac cattatcgtc
     2701 tattttttta cgcatagaat tctacctctt tcagtattta cgttcatatt ttcttacata
     2761 ttgctatttg cacaatctta tttgggtggt aataccgctt ggattggaaa tagaagatta
     2821 ataatagatg atgaatttga aaaaatcttg ctttcaaaaa gttatataaa agaaatatca
     2881 tctgcacgat actcagaata cttgacatgt gaatacaaaa actttacacc aatcatattg
     2941 ttagctattt ttgaaaattt gcttgactcc tacttgcttc agaatcagag tgaggttgac
     3001 ttagatattt tttataaagt tttacctttg ctttataaag aaaaatatac tatgggattc
     3061 aattactttg taagtttaaa ttatttacta tataaggttg gatttttggg aatcatttac
     3121 gataatgaag cattaagaga tttgtcaaaa caatatttaa acaaaaatat ttcggaatta
     3181 caagatggtt ctttcgaggg cggtatacaa gatgctgttg cctctaaaca aatagtagtt
     3241 ataaatgaat ttatagcttg tttaaattcc agatgcatgc catcccaata tgatagattt
     3301 ttttataaag atagacctta tattttttcc agaaagagtc ctattaaggg gtgaaaattt
     3361 gttacatttg gattaacaag tgtcctaggg attagaaata actctagtat agctagatat
     3421 ttttgagtaa ctagaaatat cattaggcta ctcatatgat tgccagaaaa gatggctgat
     3481 gaatcttatt tatactgttg cagtaagcat tgtctaggat aaataagcta tcttgatggg
     3541 ggagattgga ataattttag tagaaacatt aaaggattat gggcaagtag cgcaggatta
     3601 ggtgatgcaa tgtgctaagt tggcttggtg ttagcagtag tattatttaa caatggaaag
     3661 tagactaaat gaaaaataaa cgttattttt ttgacacaat tttaatgatt ttactgctta
     3721 taagcacgat attttgtgtc agcccagtat ttataaaatt ggacatctta ggaactccct
     3781 ctcatgccat cttaaccttt gtattggcga taccgttatt ctatattttg tctcaatgct
     3841 tacatacttt gctattacta gtttcctcaa tcttttgtaa attaagacca atttattttt
     3901 attttatatt tgtgatcatt ataggagcta ggaaatacta tcgaattctc tttcaccaac
     3961 taatgggatt tagtccagga gtagcagtgt tttataagga gagtcaaaca actaagaatc
     4021 tgtttaaatt ttactacttc ttgtacttta caacactaat ttcatactat tttttcttta
     4081 cttttgtgta tgacaaaccg ttgcttttgc ctcttattcc attttctatt atcatagcat
     4141 tagtacaaaa actttataga attgagaatc agcaattatt tctgttaaaa tcaaaggtac
     4201 taacaatact ggaatctaag aagaattgtg agtttaatct tcaggattat catgaaattt
     4261 ggaaattgca atcaaaatct gagttgccat gcgtggcttt atcttatatc agtttaatca
     4321 agccatatct ttcagagagt gtgcgtgaac aaattgattt attagaagtt aagcgattta
     4381 aaaaaataaa tcatccaata tcactttatg gtatgttgga tgttataaaa ttaaatctat
     4441 atttacggca ttataatgaa aaaaataaat atgaatcaat gttaaagaaa attttagagg
     4501 taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat agctcgcaac
     4561 cattatcttt atctttagcc atttcagaaa tccaactttt gcttgaagtg tatatgggga
     4621 tcaaacatgt ttcaattagg agataaaacc agaataatat ttgccattat aggggcaagt
     4681 tgcatattag tcagtatgta tcttattcca cttattaaaa ctgagaataa attttgggaa
     4741 atacttttat ttatattagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa
     4801 taaattttga aatagtattg gtgagttcgc aatcatttat tgctagtggt ttagaactgt
     4861 taagtttcaa acaataattg attttaaacc ttaggtaacc tataaaaaca aataaggtag
     4921 agaaaggata tcttatctag gtagctaagt gataaaaaca cagtcgtcta tcacttgtta
     4981 ggaaactatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
     5041 aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg attttctatt
     5101 ctgagatggc ctgttgcaac agccattaat atagctttta atggtgtttt aggtggagga
     5161 gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca
     5221 attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt ggcaggattt
     5281 gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcgatgc tattacaaca
     5341 atctgggcca acaatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta
     5401 gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata
     5461 tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa attgattatt
     5521 tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga
     5581 aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc
     5641 cctctttttg tcttgtggct agagttgcat ttgttagtga gtaacttgca attgaatcta
     5701 gaaattcccc ttgattttgt ggttagtacg agtcttgctt tctgtagttt gattttatca
     5761 aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt
     5821 acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat
     5881 ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt
     5941 tttattcttg aaattgctat tattctagta tttattttaa aaattccttt tgcaatcatc
     6001 atgcttacta caatattttt ctggactata atggatatca atcatctcgt ttttaataag
     6061 acggaatttc tttttaatca aaataaatgg gaaaaagaag attcgtttga aagcgatttg
     6121 acgaaaacgt taaaggacaa aatacaaaaa tcagagttaa gctattctga cttaatgtcc
     6181 cttcttctct atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag
     6241 gatattttga aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag
     6301 ttactgctgt atgagatttc tattagtaac aataacaact ggtccaacaa ggttgataaa
     6361 attagaatac agctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta
     6421 aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta
     6481 ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt
     6541 tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga
     6601 tgaagaagta atgatgtatc ttgatggggg agcttattta agcaagcgtg cttgtcaagg
     6661 aatttgcgca gcagcaggtg tattggctac agcagcaggg aaaatagctt actgtattgg
     6721 atatggtgtt cttaatagag gttgtgatat taacgggaac ccttatcctt gggatggatt
     6781 catatctgca acagtaagat gagtaatgta gataagattc gaaaaataca catcatcgtg
     6841 tgttgggtgt atatattttt atcattcagg gcgattataa atgatacgga gtattttttg
     6901 cttatttttt tagcttttat ctactcaata gtatcactac ctctatattc tgtgaaaaat
     6961 aaaatagtat ctatctgtct agccataaat tcgattctgt taatcagttt ccccatttta
     7021 atcaataagt ttttcccaga aagttttttg acttataccg tattaataag tgtttttatc
     7081 ctagagttag caatctttca tttaattggg gaagattttg ctactaaatt gactaacgaa
     7141 tataagaaaa ttagtcagtt tagaagcaag gtgtctcaat ctccttggat aaaatattta
     7201 gagatttcta gttttatatt aactatattt ccatctattc tttacggtac agttgataat
     7261 cgtgtattgg ctcttatctt tttgataaaa atttgtgtag atactacgat aaaattttta
     7321 ttcatcagat tatttgacac aagtacttta atgaagagga gaatattttt tcttttcgca
     7381 ttggatgtta tagcttactt atttttagga tatcttttag tgattcaaaa agcaggctat
     7441 ttgttttcgg ttttacttct tttttctaat ttttcagttc catttatcaa agcaaaggaa
     7501 tacgaattat ttaaaaatag caagtaatag aaacataggt taaatcttag aacggcttaa
     7561 aatcagatat gataaaggga aatagtctta tctaggtaac taagtgctac aaacacagtc
     7621 gaggatcact tgttaggatt acattttaat catgcttaat aagaatggag aattcctatg
     7681 gggattgtat tactctgaag tttcgaatac cttagttctc gtgattttga gctgttctag
     7741 ctttagaatc cttcagaatg taaaatttta agcagtcaaa gacttagaat agcctggaaa
     7801 catttatttt atagcaattc taggcttaga attgctcata tatatgtatt tgagctgctc
     7861 gatagttagg acagctctat tctgagaaat ctgagctatc aatgcttcag aatagtattt
     7921 cgcaaatggt ttttattgaa gaggtgattg ttttatgata gtctaaaata aaactgattt
     7981 aatggagtaa atggagaatc gtcacatgaa acattttttt gcaggaattg gtgagataaa
     8041 acttgttggc tacttattgt atatatgtgt aggactagcc cctctttttc atatatatgt
     8101 cataggttcg gaactgagtt ttgtgaaaat agtgttatct attttgggag ttatatttgt
     8161 aagtatgtta actattgctc gaatttatcg gacttttcta taaagaatag tttggacttg
     8221 aactgtatct aaaaacagag gttggtcgat tatcagcctc tttcttgtcg ttgaaaagag
     8281 tgagatatat tgacttttga aaaaaatgtc ataattgagt tgggataaac ctaaaagtaa
     8341 tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct agaaattaat
     8401 ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt tctcgttaaa
     8461 ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg tggcttggca
     8521 gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga gttagagaag
     8581 ccgactctaa tcaaccactt tgggcagtag tgagaactgc cccgtgcttt tttattttga
     8641 gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc aagaaagatt
     8701 caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt tcaaagtgaa
     8761 tttttgcttg actgatttac atcatttatt tgacttatac aaaatcacac gagattatgc
     8821 tagtcaaaca aaacctgcta ttcaagctgg tgtttttatt ttagaagatt ttagaaatat
     8881 cctatgtaca atgatgtaat cgaaaggata tctttatatg agtttatcgg tgatattttc
     8941 tattctaaaa taataagttg ttgcatcgta gctagggatt tatctaaaaa tactatgaaa
     9001 ttggacgtca tattttttga ggataaaaat aaaagatccg cagttttagg tttacgaaga
     9061 gacaaaagcg gagtatttaa atcagttact ctacatttta caagcgctaa gaaatatgct
     9121 aaagttcgta aaacagatgt gaaagaaatg aaatggctat aaagattgtc cgcaggctta
     9181 agcttgcgtt ttttgttgtt taacgaaatt aaaaaacaag ctctctcatc ggaaatgttt
     9241 ttataggaat gaaggaagat gatgctatgt ttaaaaagag aatcgaaaag ggcaaaagta
     9301 gtgtctttat ctttttggag tagaagctta tgatatagaa atttgtaata aaaatgtaat
     9361 ataaaacatt tgacaaatat ttacgggggg agtatactta atataagtat agtctaaaaa
     9421 tgactatcag aaaagaggta aatttagatg aataagaaaa aaatgatttt aacaagtcta
     9481 gccagcgtcg ctatcttagg ggctggtttt gttacgtctc agcctacttt tgtaagagca
     9541 gaagaagctc cacaagttgt cgaaaaatct tcattagaga agaaatatga ggaagcaaaa
     9601 gcaaaagctg atactgccaa gaaagattac gaaacggcta aaaagaaagc agaagacgct
     9661 cagaagaaat atgatgagga tcagaagaaa actgaggata aggcaaaagc ggttaagaaa
     9721 gttgatgaag aacttcaaaa agcaaattta gaacttcaaa aagctcatgt aaaatatcaa
     9781 aaagcacaaa gagaacttag tgaaagtcca gacagaagaa aatctgctgc tagaaagaaa
     9841 ttagctgatg cattatctta tattggagag gtagagttaa aacaaaaaga ggcggaagcg
     9901 aattttaata cggaacaagc aaaagtaatt cccaaagaaa ctgagttagc tgttactaaa
     9961 caaaaagcgg aagaagctaa aaaagaagca gaagtagcta agaaaaaatt tgataaggca
    10021 gctcaagagg tagaagtagc gaagaaagaa gtagaggcta aggaacttga aattgaaaaa
    10081 cttcaagatg aaatttctac tttggaacaa gaagttgcta ctgctcaaca tcaagtagac
    10141 aatttgaaaa aacttcttgc tggtgtggat cctgatgata cagaagctat agaagctaaa
    10201 ttaaaaaaag gggaagctga gctaaacgct aaacaagctg agttagcaaa aaaacaaaca
    10261 gaacttgaaa aacttcttga cagccttgat cctgaaggta agactcagga tgaattagat
    10321 aaagaagctg ctgaagctga gttggataaa aaagctgatg aacttcaaaa taaagttgct
    10381 gatttagaaa aagaaattag taaccttgaa atattacttg gaggggctga tcctgaagat
    10441 gatactgctg ctcttcaaaa taaattagct actaaaaaag ctgaatttga aaaaactcaa
    10501 aaagaattag atgcagctct taatgagtta ggccctgatg gagatgaaga agaaactcca
    10561 gcgcc
//
LOCUS       DBEJNA010000051        10381 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEJNA010000051 DBEJNA010000000
VERSION     DBEJNA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.51"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(77..568)
                     /locus_tag="ACL3JB_001881"
     CDS             complement(77..568)
                     /locus_tag="ACL3JB_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686556.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(549..1145)
                     /locus_tag="ACL3JB_001882"
     CDS             complement(549..1145)
                     /locus_tag="ACL3JB_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0686557.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(1142..1624)
                     /locus_tag="ACL3JB_001883"
     CDS             complement(1142..1624)
                     /locus_tag="ACL3JB_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGR0686558.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(1621..2753)
                     /locus_tag="ACL3JB_001884"
                     /pseudo
     CDS             complement(1621..2753)
                     /locus_tag="ACL3JB_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2760..3056)
                     /locus_tag="ACL3JB_001885"
     CDS             complement(2760..3056)
                     /locus_tag="ACL3JB_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGR0686559.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(3587..4480)
                     /locus_tag="ACL3JB_001886"
     CDS             complement(3587..4480)
                     /locus_tag="ACL3JB_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0686560.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(4501..4695)
                     /locus_tag="ACL3JB_001887"
     CDS             complement(4501..4695)
                     /locus_tag="ACL3JB_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686561.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(5106..5231)
                     /locus_tag="ACL3JB_001888"
     CDS             complement(5106..5231)
                     /locus_tag="ACL3JB_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0686562.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(5234..5464)
                     /gene="blpU"
                     /locus_tag="ACL3JB_001889"
     CDS             complement(5234..5464)
                     /gene="blpU"
                     /locus_tag="ACL3JB_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR0686563.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(5667..5957)
                     /locus_tag="ACL3JB_001890"
                     /pseudo
     CDS             complement(5667..5957)
                     /locus_tag="ACL3JB_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(6003..6236)
                     /locus_tag="ACL3JB_001891"
     CDS             complement(6003..6236)
                     /locus_tag="ACL3JB_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0686564.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(6242..7234)
                     /gene="plsX"
                     /locus_tag="ACL3JB_001892"
     CDS             complement(6242..7234)
                     /gene="plsX"
                     /locus_tag="ACL3JB_001892"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0686565.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(7231..8001)
                     /gene="recO"
                     /locus_tag="ACL3JB_001893"
     CDS             complement(7231..8001)
                     /gene="recO"
                     /locus_tag="ACL3JB_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0686566.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(7998..9167)
                     /locus_tag="ACL3JB_001894"
     CDS             complement(7998..9167)
                     /locus_tag="ACL3JB_001894"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0686567.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            9316..10326
                     /locus_tag="ACL3JB_001895"
     CDS             9316..10326
                     /locus_tag="ACL3JB_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0686568.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         3345 a         2196 c         1524 g         3316 t
ORIGIN      
        1 aatataagaa ttacaagtta acaaaaccga aatgatttca tatcattatt aagtaaagaa
       61 aaaaatttta gtatttctaa aaactattta taatagacat tatagcatta aataaaaatg
      121 gtacagaaaa cactactgtc aatcttaaat ttttaaatct cgcataattt gttatcccaa
      181 ttagtaatac tgtcaatacg ctgaaatagg caaactttat atccgatgga ttaaataaat
      241 aacaaagtaa aatgctaaaa cttaaggtta tatttttaga taaaagaata tctccaaagt
      301 tcctcttatt cttatcaaaa aataatgtaa tcagaaagag agaaaatcca tattcaataa
      361 gagttgctat aaatgtgaaa acaacagaaa tcactgtcaa tattgtttct attttaattg
      421 taaaaagatt agatagttca gataatttat caatttgttc atctaaaatt cccgacttca
      481 tcagtaaatc aataaacaaa tataaaagaa aaagataaat aatcagattc attaatttgt
      541 ataaactatt atttgtttga aatttcataa acccgtcctt cctctattaa aatcctttga
      601 gatttgctaa tcaattcttg attcaataaa ttatgagata catatataat agtagagctt
      661 tctttcatgg aaattaagcg tttagcaatc atatcaatac ttcttgcatc cactgttgat
      721 aaagtctcat caataaaaat ataatcccaa tttttagcaa aaattaagga taagcctaat
      781 ttgaattttg ttccagtaga tgctgtcata tagttatctc cgattttatt atcaaaaaaa
      841 gtattaattt gttctttatc ctcaaatgat agatggattt gaaaagaatc acacaacaac
      901 tgcaaatttt cttctatagt aaatggaaca accccaagct gattggtatc aaggtatagt
      961 acatctttgg agacacaatt ctttaaacca ctatcaaaag tctctagccc agctaaaagt
     1021 tgtagaaggg tgctctttcc tgaaccattc tctccttcaa ctctgtaaat tcccttatca
     1081 atctctagtg atatattttt caatatacat ttatcataac ttttagattc attttcaatt
     1141 ttcataattt aattccctct atcaacgctg ctaaaattaa taaaagataa gaaatgatat
     1201 accattttaa attacttttt atataaataa gtatattttt aattccccta tccttcaata
     1261 atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt atttcaataa
     1321 gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga ccagatatac
     1381 ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa atcggaaaac
     1441 agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat gtaaattgta
     1501 attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag cttaaaagta
     1561 aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa ccactttttc
     1621 tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata aaaccagaaa
     1681 actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct tataatagac
     1741 ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac tttttatatc
     1801 attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta agaaagagat
     1861 taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt tagaatgatt
     1921 aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat gattccctat
     1981 tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg gtatttttgt
     2041 gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa gaatactaat
     2101 caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca atataaatag
     2161 actgctacga aatctttttt gactcattcg actgctttta aaatagaaat tactcgcatg
     2221 attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat aaattacaac
     2281 ttgtccttgt tctatagaca atagtcctat agataaaaat aagaacaatt tacttataat
     2341 tgaaaacaaa ctaggtagaa ttaaagaaat aatttgaata gctatcaaac aaagagtaat
     2401 ggataaataa aaatatccaa taatatctag aaaatacaaa ataaataaat gaatgattgt
     2461 aaaatttgga aagaataata tttcttgaca atggcaagaa gatagagaaa aatatagttt
     2521 ttccttatat agaaagtatt tattttttta ctttggatag gcagtttcat attataacga
     2581 ttcaaagtag cgtaatctac taccaaaaaa agtaaaaata atttcccttg aaaaggaaga
     2641 tagcttttaa aatagattga caaacttatg ataacaaaaa acaaaagggt tatcccaata
     2701 aaattaagat aacctaaaat actttcacat tcttttttag aaagtatttt catctagttc
     2761 taccatagag ctgctttagc agcacctttc tttttcaata tataaagaac tgttgctgca
     2821 atacccgaac caatagaacc tactcctgtg attgcaccta caattgaaat tactgctgta
     2881 actgtactat aagcactaat caaattgact acagtagcag cagcttttgt cgaaattcct
     2941 aatgtcccag ccaacatagg aaaagaaaca acacctaagc ttaaccaact aatgactgct
     3001 aacattgctg aaacaataag aaatttatta tgaaattcca ttcttttaga tttcatttta
     3061 gtgtactcct tttgtatatt atgtatgttt tattgagagt taattcgcac atgttgtatt
     3121 cctaactctc ttcaaatgtt cgtctatatt ttatactact tttattaaca tatctataat
     3181 aaataaatta ctactacatt ttcctagatt atcaaattac ttttatatca ctaagactca
     3241 ataaaagata atgtctattt aacttttata cgattactac cttcttttta gtttacactt
     3301 cctacatcat aaataaacat actcaaccct cacaatctcc aaataactct tctatatcat
     3361 tgaaaattga gtttcatcct ctatactaat gtaggacatt cctttaatcc aatataagaa
     3421 taccttgttc cattaatctc tacccgatat tatagataga accaaattcc tatacttaaa
     3481 aggacaaata acgttccaac cataataaac ctcctttctt tttgagaacg ttttctttat
     3541 aggtttagta tagcaaaaac atgaaaaaaa caacatgact tagaagtcag gttgttggga
     3601 aatctatctg tttttctgct aaaattctct gaactaatac ctgatcgtct agcaattctg
     3661 ctagagaaat cgccttttca tagaaacttt ctgcctctaa aatattcttg tctacaaata
     3721 aagcatattt tgcctttagc aaaaatagat gaggtcggta aaaaacatgt cttgttttag
     3781 caataatttt ctcaaatgtt tgaatatata tcagactatc ttctgtctga atttggataa
     3841 ataggctcag aagaactttt tccatttgaa ctaggctagc cttatcttca tattctgaac
     3901 atagcaatac tttttgagct aactcctcaa aatgttcttt atcttctaat cccatagcac
     3961 aacaaaagaa atacaattca ataatcaaca aatcatttac agaaaaatat ttctttttta
     4021 ataactgctg gaaatattct tccactaacc ctaaaccgta ggtcacatct gaactaccat
     4081 aaatatcaaa acgagcttgt gtcacatcca caattaactg ctcttcctca ggcaaattct
     4141 cataatagtt ttcatatatt tcctcaagta tagcttcttt tcgttcgatt cttcccttat
     4201 cagcgtaggt ttgagaatga atcagctcat ctttgagttt taggaatcct tttggaatct
     4261 ctataacctt aacatccaca atattctgta atgatactcc aagtttatcc gcaatcaata
     4321 ataatttagg aagtgttgct aaagcttgcc cattttcaat acgtgctagc tgacgaatcg
     4381 tcaactctga ttcatcacca caaatatcta tctgagtttt tccacaagat cgcctaatag
     4441 ttttgatttt ataaccaatt tcacgtttca actcatccat agtaatactc cttaagttga
     4501 ttacaaagat ttctttttct tcctaattct tttgtcaatc atatataaaa cgataagcga
     4561 aaacagcggt agaacaatat aactcttttc actcattatc agctgaaatc ccagggttgc
     4621 tagtatctta aagatgaaaa tattcatcaa aaatagaaaa acaaatacta aaaaatattt
     4681 taaaaccttc ttcatttctt ttcttcaact ttcctaattt ctacacctat tttatcgaaa
     4741 atatatataa aactccaaat aaacacttca actgcacttt ttttggcaaa aaatagacag
     4801 aacaaacatc ctacctacta aaaatatgat atgaaaggaa aatgattttt tactgacacc
     4861 ctaggcaagc ttgggacaaa taaatcattg atagcaacat ttacgacatc ctatttaaag
     4921 ttccttcaat ttctaatgtc cccgctattt ctaagccacc tctggtatga tctattccta
     4981 gtcagaatag ataacaccgt tctaaattac gattcatagt tactcctttt ttgactcgtt
     5041 actataagac tcctatttac atgcgcaaaa taattttgat tcagattcat catttatagt
     5101 tttgattatt ttttaacaga tttttctgtt ttcttctccg aagactttaa aaattttttt
     5161 ctaattaaat catccatata aggaccaaat ataccaacta ctaaaccaat aataaaactt
     5221 ttaaaatcca taattaccac caacatgtcg ctgcataggc cacacctcca agtatagctc
     5281 ctcccacagc accagttgct gcaccttgcc atgttcttgt tttaattcct agctgaagac
     5341 ctcgtgctgc tcctcctcca acacctgctt tggcaaaatc tccccaattg catccgccac
     5401 cttcaacgca agcaagcatc tcagtatcca taatttcaaa ttgtgacatc gtttttgtat
     5461 tcataacgaa tacctctttt ttatttttaa tatttgtctt gttacaaact tgacaagttt
     5521 agtataacag tatctattaa tttttttcat ccaaatcttg aattggcatc gaaacgtctt
     5581 gaattagctt ttttgtttca aaatcatctc tatttttaaa aaagatgttt tctaatcact
     5641 tttttactat tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca
     5701 atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaaacatt
     5761 ttaaacgttt ttactttggc aaagatattc tcaaccttgc ttctctcctt agatagcgca
     5821 tgattacagg ctttatcttc aactgttagc ggcttgagtt tgctggattt acgtggagtt
     5881 tgtgcttgag gatatatctt catgagccct tgataaccac tgtcagccaa gattttacca
     5941 gcttgtccga tatttctcat ttctaaaaac catctacttc cgttgacttg gaactccgat
     6001 tgctattttc cttgaatgat tttaaccaca tctcctacgt tttggagttg gtcaatttct
     6061 tcatcgctga tttcgatact aaattcatct tccagagtca agataaactc catcaagtca
     6121 acagaatccg catccaaatc gtctttcaga ctcaaggatt ctgtcacgac aaagtcctct
     6181 ccctgtcgct cttggataat ggtcacaata cggtcaaaaa tttctttttc tgtcatctct
     6241 tttattctcc tgaaaattca cgcgcagtct gggcaactac gtctgtttct agcatggtac
     6301 gaatctggcg aatcgtacta taaacagcct tggcatcgct tgagccatga gtcttgacaa
     6361 caggtgcctt aacaccaaac aagaccgctc caccaacatc tgaataattg agctgttttt
     6421 tcaaacctct gaggctgtcc ttgagaagga gggcacctag tttcgctcga agaccaccac
     6481 ctgtaatagc tgtcttgagc aagcccatga ttcccatagc tgtcccttcg atggatttga
     6541 gcacagcgtt tcccgtgaaa ccatctgcca caacaacatc tgcaacgcca ttcatcaaat
     6601 cacgcgcttc cacatttccg ataaagttca aactttcatc agccactagt aattcataag
     6661 tttccttacg aagcggatcg cccttgctac tctctgttcc gttattgagc aagccaacac
     6721 gtggttgcgc aatgccacga acatttttag catagaagga tcctagaacc gcgtattgat
     6781 ggaggtgctg ggctgtattt tccgcattgg caccgaggtc tagcatgtca aatcccttcc
     6841 catctacagt cggcaaagtc gacataagcc caggacggtc gatattcttg atacgaccca
     6901 cgatgaagaa tccagcagcc aacaaggcac ctgtattccc agccgaaagg acagcgtctg
     6961 cttcaccatc tttgacagcc ttggctgcca ataccatact ggcatttttc ttattcctaa
     7021 tagctctcgt aggttcatca tccgaatcaa tcttctcatc cgtatggata atgctgacgc
     7081 gctctgtcgc tgtcagatat tgcttgattt tagcttcatc tccgtaaagt tgaacctcga
     7141 tatctgaaaa gtcagatagg gcttgattga caccctcaac aatggcctga ggtgcgtaat
     7201 cgccccccat ggcatctact gcgatttttt tcatttcttt tcctctttta gtaattgtcc
     7261 ccagtctgct agggaatcaa taaatttctt tgattttagg tgaatcccaa cgtactcttc
     7321 atataattga tccataaatt ggcgtagctc ttgcttgatt ccaggcttga gcgaaatggt
     7381 ctccaaagtc tcaaaatcaa tagcttgaaa ttgattgagc agatagggga tattgggatt
     7441 gagatgacaa cgtctcttat cctcatgata atgctctgga cagaggcagg ctccatattt
     7501 gaaagaaaag tcaaaagcct gaccaacccg atggcagaag acacactcat taaaattgag
     7561 gctgattcca aatcgagtca aaatttgaat ttcaaaaata ttggtcaaaa cctgataatc
     7621 caagcctgct tccatcaact ccaaagtctt ttgcaaaaaa gcaaacaagg gagcatcctg
     7681 ctgattgtcc tgcaaactag catctgcaag agctgccaca taggtcgcat aggccatgac
     7741 aaagaggtca ctattaatct tgggaaaagt catgacctca tgatagtctt cgatgtaact
     7801 gagtccgtca tcattgattc gcaagagaaa tcgtgccagc accaagggct gaataacagg
     7861 cgccagctta gactgaccag cgtgtttgac aaaaaacatg cgtttgccaa cctgctctgt
     7921 aaaaattttg acgagcttgt catcctcacg aaaattgcga ttgtaaagca ccaagccttg
     7981 actcgtgata gactgaatca tgcttctctc atgtactcct caagtcgttt catggcttct
     8041 ttgatagtct ccatgctggc tgcataagat aggcggacgt agccttcccc gtaacgtcca
     8101 aaggctgcac cagggataaa ggcaacggcc ttcttctgag caaaatcctt cagaaaagca
     8161 aaggagtctt gattgtagcc cgctggaatt ttagcaaaaa tatagaaggc accgtctggt
     8221 ttgataatct caaaaccaag agcagtcatt ttttcgatga tatagtcccg acgttggata
     8281 tattccttct tcatgggctc cgcatcgttt ttaccagccg tcaaggcttc taccgcagca
     8341 tgttgcgcca tggtatttgc ggcagtgacc aagtactggt gactcttgat taactgggct
     8401 gtgaaggtcg caggagcgaa aatcagcccc aaacgccaac ctgtcatggc atgcgattta
     8461 gacaaaccat tgataataat agcctggtct ctcaacatcg ttcctagaga cacatgggct
     8521 tcgcctgtgt aggtcaattc tgagtaaacc tcatcacaga caacaaaaat ttcgtacttg
     8581 cgtaaaacag ctgccaaggc ctctaactgc tctcgactgt aggtaattcc tgtcggattg
     8641 gctggatagt tgagaataac cgccttgagc ttatcaccct gctccaaaat ggccttctcc
     8701 aacatctcag gagtcaagac aaaaccattt tcagtcgtat caatctcaac aatttctgcc
     8761 ccaactaagt taacaatcgg ttcatagcct ggataagcag gagctggcaa aagtaccttg
     8821 tctccctctt ccaaaatagc cgtcaaagtc gcagataaag cctctgtcgc cccaattgta
     8881 accaagattt cattttcagg agcatagtcc agttggtact tttccttaac aaagtcactg
     8941 gctgcctgac gtagagtcag cagaccactc atccctgtat agtaggattg gttctgatca
     9001 atcgctcgct tggccgcctc cttgacatgg tctggcgttg taaaatcagg ttcccccaag
     9061 gtcaaacgca agaccccagg aatctccgaa ataacctggt caaactgacg aatcaacgaa
     9121 acttgaattt tatctaactg tttattaaag cgcttagtta agtccataga tacctcctac
     9181 tttcaaaacg tatctctatt atactacaaa agccccccga ccgcaaaaat acattagaga
     9241 atagctttcc actttctatt ttacttttcc tgtttatagg tctataatgg taatagattt
     9301 tatttggagg tttttatgtc atttctatca aaaaatggag caggtatctt ggcctgcctt
     9361 ctcatttcca tcctatcttg gtacttagga ggattcttcc ctgtgattgg cgcgcccgtt
     9421 tttgccattt tcataggcat gctcctacat ccctttctct cgtcctataa acaactggat
     9481 gctggtttga cctttagttc caagaagttg ctccaatatg ccgttgtctt gcttggtttt
     9541 ggtctcaata tctcgcaggt cttcgcagtt ggccaatctt cactccctgt catcctgtcc
     9601 actatctcaa tagctctgat tattgcctac ctcttccagc gtttctttgc actggataca
     9661 aaactggcta ccttggttgg agtaggttct tctatctgtg ggggttctgc cattgcagcg
     9721 acagcgcctg ttatccatgc taaggaaaag gaagtagccc aagccatttc cgttatcttt
     9781 ttcttcaatg tcttggctgc gctcatcttt ccaaccctcg gcacctggct tcatctatcc
     9841 aatgaaggct tcgccctctt tgcagggact gcggtcaacg acacttcctc tgtaacggct
     9901 gccgccagcg cttgggacag tctttaccaa agcaataccc tcgagtctgc aaccattgtt
     9961 aaactcacac gtactttggc cattatccct atcacgctct ttctatccta ctggcaaagt
    10021 cgccaacaag aaaacaagca aagcctacaa ctgaaaaaag tcttcccact ttttatcctt
    10081 tactttatcc ttgcctctct cctcactaca ctactcacct ctctaggtgt gtccagtagt
    10141 ttctttaccc ctctcaaaca actctctaaa ttccttattg tcatggccat gagtgctatc
    10201 ggtctcaaaa ccaatctggt cgctatggtc aaatccagtg gaaaatccat tcttcttgga
    10261 gccatctgct ggattgccat catcctcacc actcttggta tgcagaccct tatcggcatt
    10321 ttctaacact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtatatatgt
    10381 t
//
LOCUS       DBEJNA010000052        10057 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEJNA010000052 DBEJNA010000000
VERSION     DBEJNA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.52"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            197..1687
                     /gene="mgaSpn"
                     /locus_tag="ACL3JB_001896"
                     /gene_synonym="mgrA"
     CDS             197..1687
                     /gene="mgaSpn"
                     /locus_tag="ACL3JB_001896"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0686569.1"
                     /translation="MRDLLSKKSHRQLELLELLELLFEHKRWFHRSELAELLNCTERA
                     VKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNE
                     GCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQY
                     FSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGH
                     FMEIDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFID
                     ESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELF
                     TEFILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHT
                     KHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLE
                     DSSYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2049..3044
                     /locus_tag="ACL3JB_001897"
     CDS             2049..3044
                     /locus_tag="ACL3JB_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0686570.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            3171..4475
                     /locus_tag="ACL3JB_001898"
     CDS             3171..4475
                     /locus_tag="ACL3JB_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HGR0686571.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGGGYEDKVNAAITTNSLPDVITLDG
                     PNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYNKK
                     MFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYMPL
                     IWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYPML
                     LSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASEFV
                     KFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVAYP
                     QVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            4571..5473
                     /locus_tag="ACL3JB_001899"
     CDS             4571..5473
                     /locus_tag="ACL3JB_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686572.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            5475..6320
                     /locus_tag="ACL3JB_001900"
     CDS             5475..6320
                     /locus_tag="ACL3JB_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686573.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            6330..7649
                     /locus_tag="ACL3JB_001901"
     CDS             6330..7649
                     /locus_tag="ACL3JB_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0686574.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(7859..7931)
                     /locus_tag="ACL3JB_001902"
     tRNA            complement(7859..7931)
                     /locus_tag="ACL3JB_001902"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7896..7898),aa:Lys,seq:ctt)
     gene            complement(8196..9467)
                     /locus_tag="ACL3JB_001903"
     CDS             complement(8196..9467)
                     /locus_tag="ACL3JB_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0686575.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            9737..9976
                     /locus_tag="ACL3JB_001904"
     CDS             9737..9976
                     /locus_tag="ACL3JB_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686576.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
BASE COUNT         3283 a         1566 c         1987 g         3221 t
ORIGIN      
        1 ttagacttga atttgattct gtattcacgc cctcaataga cggtaaaata agaaaattgt
       61 ttatatattg tctccgtagt gttattatac gaaataaaag attttaggaa aagtcgttat
      121 atcatgctat acctattctt tgtggtataa ttgcaagagg tttaatccga taatttataa
      181 agagagaaag atattcatga gagatttatt atctaaaaaa agtcataggc aattagaatt
      241 attagaatta ttagaattat tatttgaaca taaacgttgg tttcatcgtt ctgaactagc
      301 agagttatta aattgtacag aacgtgcagt caaagatgat ctatcccatg ttaaatctgc
      361 ttttcctgac ttgatttttc attcttctac taatggtata cgcattatta ataccgatga
      421 tagtgatatt gaaatggttt accatcattt ctttaaacat tcaactcatt tttcgatttt
      481 agaattcatc ttctttaatg aaggttgtca agctgagagt atttgtaaag aattttatat
      541 cagttcatct tcgctctatc gtattattag ccaaatcaat aaagtgatta aaaggcaatt
      601 tcaatttgaa gtcagtctga cccctgttca aatcattgga aatgagagag acattcgtta
      661 cttttttgca caatattttt cagaaaaata ttatttccta gaatggccat ttgaaaattt
      721 ttcatcagag ccactatctc aattgttaga attggtttat aaggaaacaa gctttccaat
      781 gaatttgtca acgcatagaa tgctaaagtt gctcctagtt acgaacctat atagaataaa
      841 gtttggtcat tttatggaaa tagataaaga ttcttttaac gaccaaagtt tggatttttt
      901 aatgcaggca gaaggaatag aaggtgttgc tcagagtttt gaatcagaat acaatatctc
      961 tttagatgaa gaagttgttt gccaattatt tgtgtcttac tttcaaaaaa tgtttttcat
     1021 agatgaaagt ctctttatga aatgcgtaaa aaaggatagt tatgttgaaa aatcttacca
     1081 tctattgagt gattttattg atcagatttc agtcaagtat cagattgaaa tggagaataa
     1141 ggataatctg atttggcatc tgcataatac cgcacatctg tatcgtcaag agttgtttac
     1201 tgagtttatt ttatttgatc aaaaagggaa tacaatcagg aactttcaaa atatttttcc
     1261 aaaatttgtt tcagatataa aaaaagagct ttctcactat ttagagactc ttgaggtttg
     1321 ttctagttca atgatggtaa atcatctatc ttataccttc atcactcata ccaaacattt
     1381 ggtgattaat ttgctacaaa atcagcctaa actaaaggtt ttagttatga gtaattttga
     1441 tcagtatcat gcaaaattcg ttgcagagac actttcttat tactgtagca ataattttga
     1501 actggaagtt tggactgaat tagaattatc aaaggaatct ttagaagatt catcttatga
     1561 tatcattatt tctaatttta ttattcctcc tattgaaaat aagagactca tctattcaaa
     1621 taatataaac acggtctcac tcatatattt gttaaatgcc atgatgttta ttcgattaga
     1681 tgagtaacca aaaataacaa aaaaacgcta tttcgcgttt gaactgtacc tcaaaagtta
     1741 gacagaaaaa atctaatttt tggggtgttt ttgttaagaa aagaccttca atcatttaag
     1801 caaaatgtac atctagattt atagccctct aaaactcttg ctttttttgt agaagatacg
     1861 aaaaaagcca taaaaccaag gcttttcctg ttttatgtag atgtttacac atgaaaattg
     1921 aagtattttc aaaagctaat tggagtgatt ttattcatga tgggataaat gatctggcca
     1981 aaaatgattg agaaatagtt gcttaaaaag catttgcatg atactatata ttgaaaggag
     2041 gtgataatat ggtagaacaa agaaaatcaa ttaccatgaa agatgttgct ttagaagcag
     2101 gagttagtgt tggaactgtt tcacgtgtaa ttaataaaga aaaaggcatt aaagaagtaa
     2161 ctttaaggaa agttcaaagg gctataaaaa cattggacta tatccctgat aattatgctc
     2221 gaggtatgaa aaagaataga acagaaacta tcgctttgat tattccgagc atatggcatc
     2281 catttttttc ggagtttgcc tatcatgttg agaaagagtt attaaaatat aattataaat
     2341 tatttatttg taacgctgat agcgattcac aaaatgaaat cgaatatatc gaaatgttga
     2401 aacaaaataa agtggatgga attattggta ttacatattc tgatattgac aaatatattt
     2461 tatctgattt accgtttgta agtatagata gacatttttc ggaaaatgta tgctatgtta
     2521 cttcagcaaa ttacaaagga ggacaaactg cagcagagga actggttaga agggataata
     2581 agcaccttgc ttttattggt tcaattaata tgtatgagaa tgagactata ctcagaagta
     2641 aaggattcag agaaaaagct aaggaattag gagtagatgt ctataatttt gaaatgaaag
     2701 aacctttaat aaatcctgaa gatcagataa gaattttttt gcaatctcat aaagaaattg
     2761 atggtatatt tacaataaat gatatgatgg ctctgagagt tattagtgtt atgaaagaac
     2821 tggggaaaat agcacctgat gattaccaga taattgggtt tgatggttta aaaacttctg
     2881 tcgatcaatc ttatctagtg tctacaatag ttcaagatat tggtatgatg gcaaaagaat
     2941 ctgttgcaat gatactgaaa atgattaagc gagaagagat tctagaaaaa cgaatcgtaa
     3001 ttcccacata tttttgggga gataaaacaa caaaaaaaat ttaaaaagcg cttgacaatt
     3061 aatgaaagcg ctgttataat ataatcaaca aatgaaacgt ttcaaaaata ggctagaagc
     3121 ttgtttaaaa aataaataaa aaatgaaacg tttcaaaaag gaggaaaatg atgcgtaaag
     3181 gtacaatgtt atctgttgtt gcggggctat cgttagctat acttgcaggt tgtagtggag
     3241 gaactaactc aaaacaagcg agttcttcaa atgatattaa agtctgggta caattctctg
     3301 acgaaacaaa tgaaggaaaa gcttggcaaa aagttgttga taactttaat caatcaggaa
     3361 aaagtaagta caaggttgta actgagtata ttcctcgtag tggtggagga tatgaagaca
     3421 aggttaatgc tgctattacg actaatagtc ttccagatgt tattaccctt gatggaccaa
     3481 atacggcagc ttatgcaaaa tctaaagtaa ttactccgct agatgattat ctaaaagata
     3541 ataatatgga tgatgttttg gacagtatta aacaacaggg aacttataat gggaaattct
     3601 atgcatttgg attttctgaa tcgaatgttg gtgtttatta caataaaaaa atgttcaaag
     3661 aggccggaat tgcggaatca gagcttccaa cgctagaaaa gccatggaca tgggacgaat
     3721 ttaatacgat tgctaaaaaa ttgaaagatc attataacaa accagcaatt gattttcgta
     3781 ttaattcaaa cgatgaaatg ttgccatatg cttatatgcc gttgatttgg tcaaataatg
     3841 gttctgtcgt aaacgaagat ggaacaaagg cagaaggata cttcaactcc aaagagagtg
     3901 tagaagcagt tcaattcatt caaaatcttg taaaagaagg ctatacaact gttagtccag
     3961 tcgaaaaagg ttttgaaaca ggagagtatc caatgctttt gagtggttct tggacgattg
     4021 ctgacatgaa tacaaactac aaagatattg attttggtat ccttccttac ccagtatcta
     4081 gtaagacgaa aaaattagta tccccttcag gtagttggca attagctgtg acgacaaaat
     4141 ctgataaaaa agaggccgca tctgaatttg ttaaatttgc tacaaataca gaatcaagtg
     4201 aaattattag cttggggaat tcggtccttc caattcgtaa atctacaatt gaaaatatca
     4261 aagataaagt atccgaacca atgcgtttct tgatggaaca aaattcaaaa acagctcatg
     4321 ctcgcccagt tgttgtagca tatcctcagg tttctcgagc ttttcaacaa gcaatgcaag
     4381 atattagcta ttatgaagaa aatccaaatg tgcaaaaagt cttggatact cgtacaaaag
     4441 aaatgcaaac tgctattgat cagtcactca aataatctgt aaaaaagaag gtggaaggaa
     4501 aatgtttgga actaccttcc cctttcttgt taatagccta gtttgatata tatgattaaa
     4561 ggagatggat atgagtaaag aaactgttgt ggatacaaaa agacgtgaaa aaataaagga
     4621 taacatatta ggttatagtt ttttagctcc agctttaatt ttattaggta tctttttagt
     4681 aattccagtt ggaatggtca tttattacgc ttttacagat tattatttgt tgacaccaga
     4741 tgaaagaaaa tttgttggac ttgaaaattt tattcgatta acaaaagatc cgattttctt
     4801 aaagagcttc ttgaatactt tgaaatttgt tgtttggatt attccagttc aattgggagc
     4861 ggccttagga atggctttga ttgtcaataa aaagcgaaaa ggaaatatgt tttttaaagt
     4921 ggcttttttt gctccagttg tcatgtcctt ggtagttatt tctattcttt ggctttatct
     4981 tttaaatcca aatagtggct tattaaatgc tattttaaat aaggtaggta ttgcttctca
     5041 acctttcttg actagtccta aacaagctat gtatgcaatt gtttttgttt ctgcttggca
     5101 gggtgcaggt tatcagatgc ttttattttt aggaggaatg cagaatattc cacaagatgt
     5161 ctatgaagct gctgaattag atggattctc aaaatgggct cagtttcgtt atatcacgat
     5221 gcccctacta aaaccaacag ccctgtttgt attgttaaca actttaattt ctgcttttaa
     5281 gctgattgta caaccaatgg ttatgacgca aggtgggcca ttaaactcaa caattactat
     5341 ggtgtactat atttatcaac aaggttttac tgatcgtctt gtaggatatt ctagctcaat
     5401 cgctttagta tttacaacgt taattggtat gattagctta gtacaacgtc gcgttctgaa
     5461 ggaggatgac taagatgaaa cgatttaaac caacaacaat cttagaatat attctgttaa
     5521 ctttattggc aggactcttc ctttttccta tggtttggat ggtagtttca gctatgaagc
     5581 cagaagcaga tgtttataaa aatttgacta gttggcaagc cttcttacca agtttaaatc
     5641 ccgctgattg gtttaaacct tatcaggaag tatttgagcg ctttagtatt tttacatatc
     5701 tagggaacag cattttttat gctggaacgt ttgctattgg ttctattatt gtcaatgcac
     5761 tggccggttt cgcttttgca aaagtcaatt tttcaggtaa gaaaatttta tttggtttct
     5821 tacttgcttt acttattatt ccagtggaaa ctgtgttaat tccacaattt accattatca
     5881 attccttagg tttggtcaat aatcgtcttg cagttattat tccaggattg gcgagtgtat
     5941 ttaatattta cttatttagg aatttcttta ttgcaattcc agaagagatt cttgagtctg
     6001 caaagatgga cggagcaagt atcgttagaa ttttctttag aattatgctt ccaatgtcta
     6061 aacctgcagt tgctacagtt ggtgttttat catttatttc aagctggaat gattatatct
     6121 ggccattgat ggttttgaca gattcttcta aattttcaat gcaggttgca attacaacta
     6181 ttaatacaac tcaaccagtt tatatcaatc aggtaatggc tgtattaact atttcaacga
     6241 ttccgttgat tttggtctat gtagtcgctc agaaatatat tgttcaaggt ctgggtggtt
     6301 ccggaactgg aataaaatag gatatactta tgataaataa aacatttaca gtagaaaaag
     6361 ccaatcgttt tatagcagaa aataaacatc tcgttaatac tcaatataag cctgaagaac
     6421 atttttcagc tgagattggt tggatcaatg atccaaatgg atttgtttat tttcgtggag
     6481 aataccatct cttttatcaa ttctatccat atgatagtgt ttggggacct atgcactggg
     6541 gacatgctaa aagtaaggac ttggtgactt gggagcactt gccagtggca cttgctcctg
     6601 atcaagatta tgaccgaaat ggttgtttct caggctctgc cattgtcaag gatgatcgcc
     6661 tctggctcat gtacactggg catatcgaag aaaaaaccgg tgtccgccaa gtgcaaaata
     6721 tggcattttc agacgacggg attcactttg aaaagattga acaaaatcca gttgcaacag
     6781 gagcagactt gccagatgag ttgattgctg ctgatttccg tgatccaaaa ctctttgaaa
     6841 aagatggacg ctattactcc gtagtagctg ccaaacacaa ggataatgtg ggctgtatcg
     6901 ttctactagg gtccgataac ctagtagaat ggcagttcga atccatcttt ttaaaagggg
     6961 gagaacacca aggctttatg tgggaatgcc cagattactt cgagttagat gggaaagatt
     7021 gccttattat gtcacccatg cgttatcagc gtgagggaga ctcatatcat aacatcaact
     7081 catcgctttt gttcacgggt aaggtagatt ggggagaaaa acgttttatc ccagaatcag
     7141 ttcaagaaat tgatcatggc caagacttct atgcgcctca aacattgttg gacgatcaaa
     7201 atcgtcgtat cctgattgct tggatgcaga catgggggcg tacccttcca actcatgacc
     7261 aagaacacaa gtgggcatgt gccatgactt tacctagaat tctaagattg gaagatggca
     7321 aactaagaca attccctgtt aaaaaaggcc aatatcaaat ccaaatagat aaagattgtc
     7381 attaccactt aggaaatgat acagattatc ttgaatttgg ttatgacagt aatgtgcagc
     7441 aagtttacat tgatcgtagc catcttattc aaaaaattct aggtgaagaa gaacaggaca
     7501 ctagtcgacg gtatgtagat attgaagcta aagaattgga agttgttcta gataaaaatt
     7561 ccatcgagat ttttgtcaat caaggtgaag caagcttgac tgcaacttat tacttaacgg
     7621 tgccagctga gctatcacga attgattaaa aattaagtta tttctcctaa agaaaaagtt
     7681 ctctttctaa aatagtggaa agaggacttt ttgtgttttg ggtatataag cttagtttat
     7741 ggtatttgta aaattggtgt tggattatga tttaaactag ttttctaaag aatttgaaaa
     7801 aaattttatt taagcaaaaa aagccctata ttataagact tttcctgttg tatttatatg
     7861 ccccctacag ggatcgaacc tgtgacccac ggattaagag tccgctgctc tgccagctga
     7921 gctaaggagg caaagaaaaa agctgtattg gtgccgaaac ttcacggttt gtattgaacc
     7981 cgcgcaatta agcaggtggg caactcgctc taactgaagc tgtttccgtg tgagacggcc
     8041 tacatgctgt tagaagactt ttgtttccct aataatacaa aaaatagtcg gtcaacactt
     8101 aagtgtgaag tcgtacacca cagcgtttct atacttatat gataccactt tttcaaaaaa
     8161 aatcaagagg aaagtgcaat tttttgaaaa ggatttcaga tttttcgcaa acgatcgata
     8221 gcttcctttc tttgagccaa agcccgttca tatttaccag tatcttctgc ttggaaatag
     8281 tgatgattac gaattttttc tggcagatag tcttgcttga tccaatttcc aggatagttg
     8341 tgtggataga gatagtcttg ggcattcccc agttccttgc ttccactgta gtgcccatca
     8401 cgcaggtgtc gcggaatagg caagtgccct gatgttttga ggtcagcaag tgccttatcc
     8461 atagctacat aggctgagtt ggattttgga gaaagggcca aatcaatcac gacattggca
     8521 atgagaatgc gggcttctgg gaacccaatc ttctgggcag catccagagc agtcacggta
     8581 tgaatctggg cctcaggatt ggctaagccg atatcttcat aggcgataac agtcaagcga
     8641 cgagcgagac taggcagatc cccagcctca atcaagcggg cagtatagtg gagactggca
     8701 tccacatctg agccacgaat agacttttgc agggcagata gaacatcata gtgaccgtct
     8761 ccatccttgt ccatagtgat gtagcttctc tgaagactat tttccatgat gtctaaggtg
     8821 atgtggcgaa tgccctcgtc attctcaggg gtagagagaa cagccaagtc cagtgagtta
     8881 aaggcagagc gaaggtctcc gtttgtagag gttgcgatga aatccagcgc atcctcatct
     8941 agttctattg gaaaatcaaa accacgttca gggttactta gagctatctg cagggcctct
     9001 ttgacgtctt ggttagacag aggttccaac tcgaaaattt gaacacggct acgaatggca
     9061 ggagtgacag agaagaaagg attttcagtc gttgctccaa tcatgatgac cagtccactt
     9121 tccaagagag gcaagaggaa gtcttgcttg gtcttatcta gtcgatgaat ttcgtctagc
     9181 aataggacga gaccaccaga aaatttagct tcttccgaga tttcttgcag tcgcttttta
     9241 ctatcaactg tcgcattgaa agttcgaaag gcatacttgg tcgttccagc gatggcagag
     9301 gcaatactgg ttttgccgat tcccggaggg ccatatagaa tcatggagga caggcggttg
     9361 gcttccacca tgcggcggat gatttttcca ggtccgacca gatgctcctg accgatgacc
     9421 tggtcgatgg ttttagggcg catgcgaagc gcgagattgt ctggcatagc agtcctttct
     9481 aacgtggatt tgagtagaat gactcatcta ctatatctta ctatgtccat tctagcctat
     9541 tagttgtgat atttcaatgg ttttgtaata atcagggagt gagatagaat cttttttact
     9601 atttaattta atgaggagag gtatcagcat gagagatttg attttcctta aagctcaaaa
     9661 taggatagtt gagcctaaag aagtggaagt gctgacttga gaaataatat tgctgaatgt
     9721 cattgtatga actataatga aaagagaggt gataagcaat ggaaatgatg gaccaagtca
     9781 ggaaattttg atttttacaa aacaaattcg tcattggatt cttagtgatc aagttatttc
     9841 agggaaaaga aaacttttct tccgggaaga tactccaaaa gagattttag atttgtacga
     9901 aaacattaaa tctaaacttg attttgctta ccaagaagtt cattctaata atgggttgaa
     9961 aaaatatgaa aaatagaata attgatgttt tgaagtagta aatcgcctcc ttgtactaac
    10021 tgttgaaaat cctgatttcg aagacttgag agttaat
//
LOCUS       DBEJNA010000053         9604 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEJNA010000053 DBEJNA010000000
VERSION     DBEJNA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.53"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            229..324
                     /locus_tag="ACL3JB_001905"
                     /pseudo
     CDS             229..324
                     /locus_tag="ACL3JB_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(577..1197)
                     /locus_tag="ACL3JB_001906"
     CDS             complement(577..1197)
                     /locus_tag="ACL3JB_001906"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0686577.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1197..1679)
                     /locus_tag="ACL3JB_001907"
     CDS             complement(1197..1679)
                     /locus_tag="ACL3JB_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0686578.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKMSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1679..2521)
                     /locus_tag="ACL3JB_001908"
     CDS             complement(1679..2521)
                     /locus_tag="ACL3JB_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0686579.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2616..3416)
                     /locus_tag="ACL3JB_001909"
     CDS             complement(2616..3416)
                     /locus_tag="ACL3JB_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0686580.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPFYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3560..4939
                     /gene="glmU"
                     /locus_tag="ACL3JB_001910"
     CDS             3560..4939
                     /gene="glmU"
                     /locus_tag="ACL3JB_001910"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0686581.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVIVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4949..5494
                     /locus_tag="ACL3JB_001911"
     CDS             4949..5494
                     /locus_tag="ACL3JB_001911"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0686582.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5506..5820
                     /gene="macP"
                     /locus_tag="ACL3JB_001912"
     CDS             5506..5820
                     /gene="macP"
                     /locus_tag="ACL3JB_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0686583.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5837..6529
                     /locus_tag="ACL3JB_001913"
     CDS             5837..6529
                     /locus_tag="ACL3JB_001913"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0686584.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6606..7097
                     /gene="rocS"
                     /locus_tag="ACL3JB_001914"
     CDS             6606..7097
                     /gene="rocS"
                     /locus_tag="ACL3JB_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0686585.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7195..7785
                     /locus_tag="ACL3JB_001915"
     CDS             7195..7785
                     /locus_tag="ACL3JB_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0686586.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7794..9428
                     /locus_tag="ACL3JB_001916"
                     /pseudo
     CDS             7794..9428
                     /locus_tag="ACL3JB_001916"
                     /inference="COORDINATES: protein motif:HMM:NF021615.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
BASE COUNT         2974 a         1669 c         2055 g         2906 t
ORIGIN      
        1 agttcatgta cacctgatat gatgcgtttt ataattttaa agactttttg accagcctca
       61 tttttttaac ttgatactca gtgaaaagca aagattaaac taggaagcta gctgtaggct
      121 gctcaaagaa cagctttgag gttgcagata aaacttgtga ggtaaccaac atatataatg
      181 tgaagctgac gtggtttgaa tagattttag aagggtatga gtctggaagt tttaatggat
      241 aatgcaagat tccatagaat gggtaagcta gagttcttat gtgaagagtt tgggcataaa
      301 cttttacctt ttcctcccta ctcatcttag tatagaaaag tgaatctaaa atagtacata
      361 actgcttcta aaacattctt ataaattgat ttaaattctc aaatcatatt attcagttct
      421 tatttcattt tgctctacaa tcctgttgag aagacacgtg ttcatatcaa aaaggtattg
      481 gcaagttgca ataccttttt acaaggttct tttgtcttat ttttgtttca actgactata
      541 tctcctatgg ttctagttca gaaggctagg ctataattat gattgataag aagtatcatt
      601 ccaagtattg agagtgaatg tttcaaaatc atgggtttct ataatggtca ggctggcatt
      661 tgctagaccg ccatctttac gaagaagtgg ttctttatag cctaggagag tacgaagact
      721 ggcagtaaga ttggcgccgt gtccgacaat tagaatacgc tcagctggac tatcttttaa
      781 tgatttgata aattggatgg tccgctgagt tgtactatag agggattcgg ctccgaacat
      841 tcgagtgtca aattgagcaa gatttgaacg aaaagcctgg atttgttgcg ggtaaatagc
      901 ttccagggtt gcaattttca aaccttctaa cttcccaagt tgccattcac ggagattagg
      961 aacgatttct aaagaacagg gggtatggag ttgactttgg ataatctcag cagatttgac
     1021 cgctcgaggt aaatcacttg aataaatctg atcaaaagga atttccttga gatactggcc
     1081 aagtcgtttt agggtttcaa tggatccagg aagaagagga gaatcaccgc tagcaccttg
     1141 aaaacgacct tcttggttcc agagggtacg accgtggcgg acaaagtaga gtttcattac
     1201 ttgatgtcct ccaaaatatc tacaaagtct gcctttacaa agctagccaa gtcttgtggc
     1261 gcgacgataa tgctgtgtcc gacttcgcct gcagagacaa tcattcgatc caaatctaga
     1321 gcaattttat cgataaaaat gggataattg tgtttctgac gaattccgac aggattattg
     1381 gctccatgaa tgtaaccagt tgttttttct aagtcctttt gtggaatcat gctcattttt
     1441 ttattgccag aaattttagc tagtttcttt tcagacaagt gctgagtgat agggacaatt
     1501 ccgataatcg gtccggtctt gtctcccaaa agcgccaagg ttttgaaaat ctgatctcgt
     1561 tcataacctt gaggaagctc tccttctagg gcattgattt gaatcccctg atgagggata
     1621 gctgctttag ataggatttg ttccaccaat gtttttttga ttttaacttt ttttgccatt
     1681 atttatattt atcctccaat tgactcatcc aaataccaag ccagattccc agcgcaaaga
     1741 agaaggcgat gatgacataa ccgacaagtg aaagtcctgt gtattggata ctttcagcgt
     1801 ttcctgcatt tggaattaag atcaaaaggg tacttgatag gacgataccg atgatgaaat
     1861 gatagacgcg tgagtggtag ttgtttaagg cataatccat caattttgaa aaaacgatga
     1921 gagttgcacc tgcaccaatt ccaatcggaa agaaggttcc caagagatca aaagttttaa
     1981 aaccagtcaa cataggagca tagagtccca aaatcaaaag taaattcgat gggctgaggc
     2041 caggaaccaa gacgccaagg gccaatagtg cgcctgctag gacgaagtta agaaagctgg
     2101 cgcttaaggt tccaacgaca aaatttaagg catagagtcc taatccagaa atgataaagg
     2161 ttgtccataa ccaagctaaa tcaatcttgt ctcggtcaga ttctcgagtt gattctttga
     2221 ggaggctagg aactgtaccg ataatagctc ccgcaaagct ccataataca aagacctgat
     2281 aattttcaag caggtattca atcgggtagg aaaataagcc gattcccaga agcataccga
     2341 tggcaactgg aataaagtac aaaacatttt ctttaaagtc tttaaaggga tgggccagaa
     2401 agccaatcat tcgttcatag attcctaaga ttgctgctag aacccctccg gaaattcccg
     2461 gtaggataaa tccaagagca attacaatcc ctttaataac gcgtgctaac catgagagca
     2521 tatatttcct ccaactattt ctatttcaaa aaatccttac tatattgtat cacaatcaga
     2581 cacaaaaaga aaaagcaaat gataaacaaa tgcttttaag gttttaaaaa aagttttcga
     2641 aaggtttctt ctttattttt taagggagag ataacgttga tatctaaatc gtggtcaaag
     2701 ccggcaattt ttcctttaga tgtgtattgg tgaatatcat aatctaaatc agttttagga
     2761 ctgctttcca aaaatcctga gtctgagccg tagaacggaa tccaaacaga ggtaaacttg
     2821 cctgtatcaa tactgtgttc ttccatgaag tagacaccaa cgtagatgcc gatgttttta
     2881 gcacccagtg atgctagttt tgctcgaaag ttttcgacac cttcgttcat attagacatg
     2941 gttttgtctt ccacgtcaag ccaatagtaa ctagggctgt aaggagaggc agcattgtag
     3001 aaaacttcgg cagccttttc catttcttgg acactttttc cagctacata agcgtagaca
     3061 gcaactggga cattccgctt ttgaagttca gtgatatgac tcttataggc cttgtctatt
     3121 ccattgataa atgaagcatc attttctttt gtcgtttgag caccactgtg aacacgaaca
     3181 atagcacctg aaatattttg tgagagggca tcgtagttga tttcctcagg acgctgccag
     3241 ccagagaggt caataatcgg tttgtctaag tgtttcaaag cctgtgcttc aatctgtgct
     3301 atattggatt ttgttttaaa cgattggctg tcattaagtg ggcgattgat gattaaaatg
     3361 aacatcataa tcccaaaaaa actaaataaa ataagtggat gaatttgttt tctcatatct
     3421 tataattcta ccctaaaaat caaaaaaaat caaaaaaatg ggttaaggaa gagactttag
     3481 agcatttttt cattcaagag tgcggaatga tttgaaatat ggtataataa aagggaattt
     3541 ctacagaaaa gggaagatta tgtcaaattt tgccattatt ttagcagcgg gtaaagggac
     3601 tcgcatgaaa tctgatttgc caaaagtttt gcacaaggtt gcgggtattt ctatgttgga
     3661 acatgttttc cgtagtgtgg gagctatcca acctgaaaag acagtaacag ttgtaggaca
     3721 caaggcagaa ttggttgagg aggtcttggc tggacagaca gaatttgtga ctcaatctga
     3781 acagttggga actggtcatg cagttatgat gacagagcct atcttagaag gtttgtcagg
     3841 acacaccttg gtcattgcag gagatactcc tttaatcact ggtgaaagct tgaaaaactt
     3901 gattgatttc catatcaatc ataaaaatgt ggccactatc ttgactgctg aaacggataa
     3961 tccttttggt tatggacgaa ttgttcgtaa tgacaatgct gaggttcttc gtattgttga
     4021 gcagaaggat gctacagatt ttgaaaagca aatcaaggaa atcaacactg gaacatacgt
     4081 ctttgacaac gagcgtttgt ttgaggcttt gaaaaatatc aataccaata acgctcaagg
     4141 cgaatactat attacagacg tcattggtat tttccgtgaa actggtgaaa aagttggcgc
     4201 ttatactttg aaagattttg atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac
     4261 agctgagtca gttatgcgtc gtcgcatcaa tcataaacac atggtcaacg gtgttagctt
     4321 tgtcaatcca gaagcaactt atatcgatat tgatgttgag attgcttcgg aagttcaaat
     4381 cgaagccaat gttatcttga aagggcaaac gaaaattggt gctgagactg ttttgacaaa
     4441 cggtacttat gtagtggaca gcactatcgg agcaggagcg gtcattacca attctatgat
     4501 tgaggaaagt agtgttgcag acggtgtgat agtcggtcct tatgctcaca ttcgtccaaa
     4561 ttcaagtctg ggtgcccaag ttcatattgg taactttgtt gaggtgaaag gatcttcaat
     4621 cggtgagaat accaaggctg gtcatttgac ttatatcgga aactgtgaag tgggaagcaa
     4681 cgttaatttc ggtgctggaa ctattacagt caactatgac ggcaaaaaca aatacaagac
     4741 agtcattgga aacaatgtct ttgttggttc aaattcaacc attattgcac cagtagaact
     4801 tggtgacaat tccctcgttg gtgctggttc aactattact aaagacgtgc cagcagatgc
     4861 tattgctatt ggtcgcggtc gtcagatcaa taaagacgaa tatgcaacac gtcttcctca
     4921 tcatcctaag aaccagtagg agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa
     4981 agaaatctat caaggaccaa tatttaaact ggtccaagat caggttgaat taccagaagg
     5041 caagggaact gcccaacggg atttgatttt ccacaatggg gctgtctgtg ttttagcagt
     5101 aacggatgaa caaaaactta tcttggtcaa gcagtaccgc aaagctatcg aggctgtctc
     5161 ttacgaaatt ccagccggaa aattggaagt aggagaaaac acagcccctg tggcagctgc
     5221 ccttcgtgaa ttagaggaag aaacagccta tacagggaaa ttagaactct tgtacgattt
     5281 ttattcagct attggctttt gtaatgagaa gttaaaacta tatttagcaa gcgatttgac
     5341 aaaagtggaa aatccgcgtc cgcaggatga ggatgaaacc ttggaagtcc ttgaagtgag
     5401 cttagaagaa gcgaaagaat taatccaatc aggtcatatt tgtgatgcca agacaattat
     5461 ggctgttcag tattgggagt tgcagaaaaa atagaggagg tcagtatggg taaatcttta
     5521 ttaacggatg aaatgattga aagagctaat agaggcgaaa aaatttcagg tcctcctttg
     5581 ctagatgata atgaggaaac taagatttta ccaacctctt cttcccgttt tggttatgcc
     5641 aatcctaagg atcatggttt tagccaggaa accttgaaga ttcaggtcga accatctatt
     5701 cataaaagcc gtcgtattga aaataccaag agaaatgtct tcaattctaa gttgaataaa
     5761 atcttatttg cggtcatctt tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa
     5821 tagaaaagga attgaaatga aaataggaat tattgctgct atgccagaag aactggctta
     5881 tctggtccag catttagata atgcccagga gcaagttgtt ttggggaata cctatcatac
     5941 aggaaccatt gcttctcatg aagtcgttct tgtagaaagt ggaattggta aggtcatgtc
     6001 tgctatgagt gtggcgattt tggctgatca tttccaggtg gatgccctta ttaatacggg
     6061 ttcagctggg gcagtagcag aaggtatcgc tgttggggat gtcgtgattg ctgacaaatt
     6121 agcctatcat gacgtggatg tcacagcttt tggctatgct tatggacaaa tggcgcaaca
     6181 accgctttat ttcgaatcag acaaaacctt tgttgctcaa atccaagaga gtttatctca
     6241 attggaccaa aactggcatc ttggtttgat tgctacagga gatagttttg ttgcaggaaa
     6301 tgacaagata gaagcgatta agtcccattt cccagaagtt ttagccgtgg agatggaggg
     6361 ggcagctatt gctcaagcag cgcatgccct caatctccca gtcttagtca tccgagctat
     6421 gagtgacaat gccaaccatg aagcaaacat cttttttgat gagtttatta tcgaagctgg
     6481 acgtcgctct gcccaagtct tgttgacctt tttgaaggct ttagattaag cggaaatttg
     6541 acagtttttc tagcttatga taagatttaa gtaaagaaaa gctagaaaac gtttcagagg
     6601 atattatgag tattgaaatg accgtcagtg agattgcaga ggtcttagga ttatctcgcc
     6661 aagcaatcaa taaccgtgtc aaagaattac cagaagaaga cacagataaa aatgacaaag
     6721 gggtaacagt tgttaccaga agtggcttga ttaagctaga agaaatctat aaaaaaacga
     6781 tttttgaaga tgagcctgtc agtgaagatg tcaaacaacg tgaactgatg gagattctag
     6841 tggatgagaa gaatgcagaa attcttcgtc tttatgaaca attaaaagcc aaggatcgtc
     6901 agttatcaga aaaagacgag cagatgcgta tcaaagaccg tcagattgct gagaaagaca
     6961 aacaattaga tcagcaacaa caattgaccc ttcaagccat gaaggatcaa gaaaatctta
     7021 agctagagct ggaccaagca aaagaagaag tccaatccac taagaaaggc ttttttgctc
     7081 gtttatttgg aggataatca aggagctgtt taggttaaat gctaacctga tggcttcttt
     7141 tgtttgtgaa tagtatagtt gattagaaca gagacagtag aggagaggta cagaatggaa
     7201 cgattagaag attacattgc ttttgactta gaatttaatc agcacgaagg acaaacacac
     7261 ttgattcaag tatcggcagt gcgttttaga gatggtcggg aaatcgatgc ctatgattcc
     7321 tatgttcata ccagcgtccc tctaaaaagc tttatcaatg gtttgaccgg gattacagct
     7381 gagaccttaa aagatgctcc tccagttgag aaagtcttag aagaattcca agagtttgtg
     7441 ggttctttgc tgatgatagg ctacaatgct gctaaaagtg atttacctat tttagcagag
     7501 catggtttag actatagcca acagtacaag gtggatttgt atgatgaagc ttttgaacgt
     7561 cggagttcag atttacatgg tattgccaat ctcaaattgc aaactgttgc ctcatttctt
     7621 ggatttcaag gtcagtctca taatagttta gaggatgctc ggatgacggc gcgtgtttac
     7681 gaatccttct tagagtcgga tcaagctagg gaattgttag agacagaaag tagcttatca
     7741 aataatcctt ttggtggctt ggacttgtct caattatttg actaggagtg cctatgaaac
     7801 ctgaaaaacc taaaaaattg ggtcttaaac agatttacct caatcttgat aaaatcctct
     7861 ttctattttt cttgattttt atgatagtgg agtatttgtg ggtaccattc aattcatggt
     7921 tggctagctt cttattagat cagacaggtt atctttttat ttcctataac aatgtcttag
     7981 ccatccttac tcattctcca ttgattagtc tagctttttt agccttgatt gtaattaact
     8041 ttctggttgc ttattttcaa ataggactcc tctttattgg tgctcgtcat ctcctctata
     8101 atgaaaagcg aaggctaatt gagtatatcc gcaaggtttt ccatgaaagt tttgaattta
     8161 tgaaaaagct aactggcgct aaagccttgt ttatcttttt ctatatagct atgctgtttc
     8221 cttttatacg gaaaatgctg aagatttatt atcttaataa aatcgtcatt ccagagttta
     8281 tccaagctta tttagaagat aaatattgga tgtggtggct gagcatccta cttctatctc
     8341 ttatctttct ctatgtctct gtcagattga tgtttgccct tccgaagatt gtatatgatc
     8401 agctgactgt tcgagaagca gtgatgttta gcttggagaa aaccaagaag agagttactt
     8461 tttatgcttg gaatttattt tacatcttgc tcaaagcaca tttattattt tatcttcctt
     8521 tgattccttt attattggct caaactttgg tagatgatat cactcagaga gagtctctga
     8581 ttcttggtat tttgaatttt gttgtgatta aaaatctcta ttatatggct ctgacttatt
     8641 ttttggttaa atttgtttca tttttgacag gaaaggagct ggatatgctt cctaggagag
     8701 aaaaagatca catcgtgcga tggggtgtca tgacttgtgc cagtcttttc tttgccttag
     8761 aaggttatat ttatctggag gctcccatgg ttcatctacc tcaacttatt tctcaccgag
     8821 gggtttccaa tgcaaatggg attcaaaata cagtagagtc cttggaaact acagcacaac
     8881 tcaaaccaga cttggtggag acggacgtgc aggaaacaaa agatgggcag tttgtcatga
     8941 tgcatgatgc taacttgaaa aatctagcag gtatcaataa aagtcctcaa gacttaaact
     9001 tggaggagct taaagggatt gatatttttg aaaatggcta ccagactaaa atttcaagct
     9061 ttgaagatta tctcagtcga gccaacgaac ttggtcaaaa attactaatt gaaattaaaa
     9121 ccagtaaaaa agatagtcca gacatgatga accgcttttt agcccgttat gctgcaaagc
     9181 tcaagattta tggacatcaa atccagtctt tagactacca tgttgtcgaa aaagtaagac
     9241 agtatgatgc cgaactgcca gtttatttca tcatgcccta caattctgtc tttcctaaaa
     9301 caagagcgac aggatatact atggagtact caaccttgga tgaatatttt gtaagcaaac
     9361 tatggacaac ggatcagaaa ctttatgtct ggactgtcaa tgattcagaa gctatcagca
     9421 aatctcttca cttaggagta gatggagtga ttacagatga tttggaaaaa gttcagcggg
     9481 aaatagaagt agcccaagaa gatccagaat atacggattt gctcttgaaa aaagcattgg
     9541 aattctttga attttagtaa taaaaaagag gaacggttgt tcctcccatg ataggtaagt
     9601 attc
//
LOCUS       DBEJNA010000054         9352 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEJNA010000054 DBEJNA010000000
VERSION     DBEJNA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.54"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            168..854
                     /locus_tag="ACL3JB_001917"
     CDS             168..854
                     /locus_tag="ACL3JB_001917"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0686587.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="ACL3JB_001918"
     CDS             855..1787
                     /locus_tag="ACL3JB_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686588.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="ACL3JB_001919"
     CDS             1798..2727
                     /locus_tag="ACL3JB_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0686589.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLKNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="ACL3JB_001920"
     CDS             2741..4180
                     /locus_tag="ACL3JB_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686590.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="ACL3JB_001921"
     CDS             4249..5826
                     /locus_tag="ACL3JB_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0686591.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKPFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7346
                     /locus_tag="ACL3JB_001922"
     CDS             5886..7346
                     /locus_tag="ACL3JB_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGR0686592.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKIIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7368..7823
                     /locus_tag="ACL3JB_001923"
     CDS             7368..7823
                     /locus_tag="ACL3JB_001923"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0686593.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            8328..8777
                     /locus_tag="ACL3JB_001924"
     CDS             8328..8777
                     /locus_tag="ACL3JB_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0686594.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
     gene            complement(8822..>9352)
                     /locus_tag="ACL3JB_001925"
     CDS             complement(8822..>9352)
                     /locus_tag="ACL3JB_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0686595.1"
                     /translation="PFHKVRLMYQDEAGFGRISKLGSCWSPIGVGPHVHSHYIREFRY
                     CYGAVDAHTGESFFLIAGGCNTEWMNAFLEELSQAYPDDYLLLVMDNAIWHKSSILKI
                     PTNIGFAFIPPYTPEMNPIEQVWKEIRKCGFKNKAFRTLEDVMNQLQDVIQGLEKEVI
                     KSIVNRRWTRMLFENR"
BASE COUNT         3234 a         1260 c         1739 g         3119 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgaaaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aaccatttga ttggcagcca cttgtttatc cagaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tgttgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagat tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt ataaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaactt agatatatta tttacatggg
     7321 agttttctaa ttggattact gattaacaaa taataaggga atattaaatg aatgatacta
     7381 ataaaaatca atactttgtt tatgaatttg atactagctt tgtagaaatg tcttattctc
     7441 agttttttga aggatattgt attctttttt caaaagaacc ctatccttct ttatctgata
     7501 tgccaatgga atttagaaaa gaatttttaa tggaaatgag tatattaggt gatgcgatgc
     7561 ttgaagtgtt aaatgcctat agaattaatt atgatatctt aggaaattca acacctgtac
     7621 ttcatgctca tttatttccg agatacatgt gggaagagga agagagaaga aaaactgtag
     7681 ttcatagata tgattcttca gtttttagca atcctgagtt tgaatttact atagaaaagc
     7741 atggaccaat tattaaaaaa ctgaggtctg ctattgatag acattataga gagtatcaac
     7801 aattattaga tgattcaaac tgaactccac attttcgatt agatttaata ccttgtatat
     7861 tacaactagg ttgtggatga tataattttt cgaaaaatat attttaggaa tgacttataa
     7921 agtaattata tcagaggtta ttaaatcaat ggtccaagct tatgctcctt attcttattt
     7981 taaggttgga gctgcgttag aaactgaaga taaaaatttt tttctggatg taatatagaa
     8041 aatgttgctt ttctcctact tgctgtgcag aacgagtata tttttacaaa gctgtattta
     8101 aaggagaacg ttcgttttca aaaatatgta ttgtaggcgg aaaaaaaggt attttatcat
     8161 cttttatagc atcttgcagg gtgtcttgtc aggtaatgat agaattttgt aatcttgatt
     8221 catttgtagt tatattggct agtgatgttg atacttataa agtatataaa cttaaagaac
     8281 tactaccagt tagttttaat caagaaaatt tataacagga gggaactatg gaattagttg
     8341 aatttaaaaa tggacatgtt aatacggttc atgagcatat cgcaataacg aaagtaaaag
     8401 agtttctaaa taatcatgat ataccaaaag ataaaggtgg catacataaa atttctactg
     8461 atttctttta caatataatt gatatggaaa ctacaactga agaaaataga ccgtgggaaa
     8521 gtcataagga atattatgat gtccattatc tgttaaatgg agaagaaata attttatata
     8581 atttcttgtc tcaaatggaa ttgtctgaat ataaagtaga tgatgattgg caacaaatga
     8641 atgggacagc tttatttagt attaaattaa agaaagatat gttacttttg ttggaaccaa
     8701 acgatgcaca taaaacaggc ctattggttg aagaaccaat taatattaag aaagttgttt
     8761 ttaaggtaaa aatttaactg aaagtacttt cagggattaa gaattttaaa atatttaata
     8821 ctcatctgtt ttcaaaaagc attctagtcc atctccgatt aacgatggac tttatcacct
     8881 ccttctccag tccttgtatg acatcttgaa gttgattcat gacatcttcc aaagttcgaa
     8941 aggctttatt cttaaatcca catttacgaa tctctttcca cacttgttca atggggttca
     9001 tctctggtgt gtatggagga ataaatgcaa aaccaatatt agtcggaatc tttaagatac
     9061 ttgatttatg ccatatagca ttgtccataa cgagtaaaag ataatcatct ggataagctt
     9121 gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt acatccacca gctattaaga
     9181 aaaatgattc gcctgtatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat
     9241 agtgactatg gacatgtgga cctactccta ttggagacca acaagatccc agtttactga
     9301 ttctaccgaa accagcctca tcttggtaca tcaagcgaac cttatgaaaa gg
//
LOCUS       DBEJNA010000055         8974 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEJNA010000055 DBEJNA010000000
VERSION     DBEJNA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8974
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.55"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(286..1134)
                     /gene="dprA"
                     /locus_tag="ACL3JB_001926"
     CDS             complement(286..1134)
                     /gene="dprA"
                     /locus_tag="ACL3JB_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0686596.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPASILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1230..1919)
                     /locus_tag="ACL3JB_001927"
     CDS             complement(1230..1919)
                     /locus_tag="ACL3JB_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0686597.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1931..2809)
                     /locus_tag="ACL3JB_001928"
     CDS             complement(1931..2809)
                     /locus_tag="ACL3JB_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0686598.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2799..3668)
                     /gene="licA"
                     /locus_tag="ACL3JB_001929"
     CDS             complement(2799..3668)
                     /gene="licA"
                     /locus_tag="ACL3JB_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0686599.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDATSI
                     KTKFDKIVPILQTIHASGKELRGEFAPFEEIKKYESLIEEKIPYANYEAVREEVFSLE
                     KRLADLGVYRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3685..4707)
                     /locus_tag="ACL3JB_001930"
     CDS             complement(3685..4707)
                     /locus_tag="ACL3JB_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0686600.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4712..5419)
                     /locus_tag="ACL3JB_001931"
     CDS             complement(4712..5419)
                     /locus_tag="ACL3JB_001931"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0686601.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5755..7242
                     /gene="tacF"
                     /locus_tag="ACL3JB_001932"
     CDS             5755..7242
                     /gene="tacF"
                     /locus_tag="ACL3JB_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0686602.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYSYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7252..8055
                     /locus_tag="ACL3JB_001933"
     CDS             7252..8055
                     /locus_tag="ACL3JB_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0686603.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8057..8866
                     /locus_tag="ACL3JB_001934"
     CDS             8057..8866
                     /locus_tag="ACL3JB_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0686604.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2821 a         1816 c         1511 g         2826 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcgc aaactaggaa gcgagccaca
       61 ggttgctcaa aatactgttt tgaggttgca gatggaagct gacgtagttt gaagagattt
      121 tcgaagagta ttatatgaga aaaatcctct actctactaa tccacttaga aaaaacgcat
      181 attatcaagt gttaaaaact tgctaatatg cgttttatta tggaaatgtt gggttcattt
      241 tctcttaaaa ttgatttttt cttagaattc tagcttaggt catttttaaa attcaaattc
      301 cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct tcttgaatca aatgatggca
      361 accgtctgat agtccatcta aaatgctagc aggaatagca aagacatcgc gtccttcttc
      421 cattgctcgc tcacacgtaa tgagactacc tgaacgcatc ttagcctctg ctacaatcac
      481 accacgacaa agtccagcaa tgatgcgatt acgggcagga aaatgaaatt tcagaggttg
      541 ttcgccaggt ccatattcac ttaaaaccag atggtcattg ccgatgtagt cttgcaagcg
      601 tttattggct ttaggataaa acacatccag tcctgttcca atcactgcaa tggtttttcc
      661 gccattctga agagctgcca tatgagctgc tgtgtcaatg cccttggcca gaccactgac
      721 aataaccagt tcattttcca agccttgaat gactttttca actgatttag ctccctgttt
      781 gctacaagca cgactgccca cgaccgctac cttcgggaat ttcaggaggt caagatttcc
      841 cttgtaaaat aaaagtacag gcgcatcata tatttcactc aaatcccaag gataacagtc
      901 atctaaaata gagaaagatg gaaatttttg aaactctttc gacaaatgcg catcgtctat
      961 ctgaaaataa cgttccataa aaacggctgg attacggcaa cctgatatat ctgcaatatc
     1021 acccaacaaa agctcctgat caacattttc accgtattct agcactttca aaatctgttg
     1081 attggtcaaa cctgattttt ttaacttata gatttcatag tttgtgattt tcataaataa
     1141 ctccatttct ttttctactc atctatctat tcgtaaaagt tcgtaaaaaa tcaaaaaaca
     1201 tccgactatt ttgtcagatg ttggaatctt taattttcgt ttttaagaat ttcttctaat
     1261 ttacgatagt cttggacact atcgatctca taaatgctat tgccttctaa ttcttcaaca
     1321 tagacatcta gctctttgat attatcctta accatattgt cccagtagag atcaacaaat
     1381 tcgccacttg cataagcctt atcgataaag ctgacaatct tttctgcagt tggagcatcc
     1441 cagaaggata caccactaag gatgcgacct gccttgctat caacaataat gtcttgaacc
     1501 ttgtagtcat ctccatagac caagaaccat tcgttggtac aatcttcacg ataaacacta
     1561 aaataagtcg aacgagtcaa atcattgcgg aacatatttt taaagagata gttatctgca
     1621 tcaataacat agctgttggc caattcttct tttacaagat agagagagta aaagttattg
     1681 tagtcagcgt atttatcatt gaaaacgaga cgaacaccgt atttctcttt caagtaatcg
     1741 aattgttctt taagataacc aacaatgatg atgatgtcat tgattccttt ttctttgaga
     1801 aactcaattt ggtactcaat taagggtttt tgattaacct gaaccaaggc tttaggggta
     1861 ttttcagtca taggacgcaa gcgagttccc aatcccgctg ctaagataat ggctttcaca
     1921 cgaatctcct ttattcttta ataataatat aaactccagc aatgacgaca agtgacgtca
     1981 taatggtcag catatctagc ggtgcaccca agaaaacaac tgcaaacaag accgtccata
     2041 ctacatagct cacgttcaag cctgtagcct tggctggttg caagcgattg atagcgatat
     2101 aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac aatcatgaga cctagcaatt
     2161 gtccattggc tactgcagta aatgactgat gagagaagag cacaatcaca agataggaca
     2221 agaacgaagt tacttgacgg attaagaggg cttcgatttc actcaattca ctttccatgg
     2281 caaaagagct aagaacactc tcacttcccc atgcaatagc acaaaccaaa gcacaaagaa
     2341 tcccaatgta gaaagaatta acctgttcaa ccttataggt ctgggcaata atccctccaa
     2401 taatcaagac aatcccaaat acagtatttt tcgaaatctt gtgcttcaaa aagaagaaag
     2461 ccaatagaac tgaaatcgca gggtaaatag ccgatacaga tgaagctaaa gaacttccga
     2521 tatacttaac tgcataaaga ttggcctgca taccgatagg gcctgctagc aaggctccga
     2581 tgataacact gacattgcga atatttaaga aaattgagag gcgaactttc ccttctttta
     2641 ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc atgagctgca gccaccacaa
     2701 agggtgacaa atctgtaaaa atcgaaaaga tataagcact aaccgttaga cccaagcccc
     2761 agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt acttttcatc tgaacctcca
     2821 taagaagcca aacctttaac agctctttgg taacgattca caccatagta accaaaatct
     2881 gcaccttgct cttccttata gacagtccat agactccaaa tagtatcttg taaaatttta
     2941 taaatagcaa tcttttcatg agaaaccggt gtttggtcac tctcatagtg agataagaaa
     3001 gtttcttcct cttgggaagt gaattcagac tctaaaaaga gggcagccaa atcccacatt
     3061 ggatcattca ttgatgaata ttcccagtca atcaaataaa gtcgtccttg aggtgattcg
     3121 ataaagtttt caggcaccaa atcgatatga caagattttc tgtaaacacc taagtcagcc
     3181 agtcttttct ctaaggagaa gacttcttct cgaacagctt catagttggc ataagggatt
     3241 ttctcttcaa ttaaggattc atattttttg atttcttcaa aaggagcaaa ttctcctctt
     3301 aattccttgc cagaagcatg aatagtttgt aatattggaa caattttatc aaatttggtc
     3361 ttaattgaag tcgcatcaag cgtaatagca gattcgatat actcatttac tttgatacca
     3421 gcttcaatat caaaaagata attttttaca tctaagccta aatcctttag tagttcaaga
     3481 ttgtactttt catcttgtcg attgataagc ttttctgtcc ctttaccaaa gaatttaaca
     3541 atgtattgct tatttgttgt tttggccaaa tagttttgat tggtcattcc acccagttgt
     3601 tcaacactga ggacttcctc ttcttgacta agtaaggaag aaattttttc tttaatgatt
     3661 ttctccacaa ttaacctcca gtacttatac ttcccactta aacactgttt taaaggctgt
     3721 gtttaaatcg gttgcaaaga cacgatgaat atctttaatt tctcttacag gttcttctag
     3781 ataaaggata tttttaagac gattggcaaa tttcttgact tccatcattt ggatagcatt
     3841 ttcaaaatca atgcgaccag aacgagatga cccaaccaaa atcaagccct tttctaaggc
     3901 atcgcgagta ttgagattga ctttatattc gctaactccc atcatgagaa tcgttccctg
     3961 aggacgaatg tagcgaatca agtcattaat agctggtcca gtaccatcac caccacaaca
     4021 ttcaaaagca tggtcaaagg ccaaatcttc aggaatatta tccgtaatat agcattcttt
     4081 ggcaaatgag aagagttcca acttttccca atgacgacca ataaccacaa tctctgattc
     4141 tggcaaagta tagttgataa tattggcaac cacaaaagct aaacttccat ctccaataac
     4201 ggcgatccgc tcccgcttgc tatgagcaag agtcaataga cgattcatag cgtgcatgcc
     4261 cacactgaca aactctgtaa tggctgcaac cgtatcttca atagcatcat aagccaccac
     4321 acgatcttta gggagagaaa caaactctct cataaagcca tcaaatccac tagacaagaa
     4381 atgggtccct gtcatgtagt tttcatagaa ttcttcatca ctctgcatag gagactgatt
     4441 gggaatcatg acaacttttt gaccaacctc gtaggttccg gtcgggtcag aaatgacggt
     4501 tccacatgac tcgtgaatca ttgccattgg aagcttttta ttcaaaatct tgggatcacg
     4561 ttttccctga tagtaacgct gatccgcatg acagacagcc atgtagttgg gacggataag
     4621 gatatgattc tcttggtcaa tagcctcttc ctgatatttg acattgataa acttaggctt
     4681 agttagttga taaatttgat taatcatttt actagtcttt ctcaatcata ctttttgcaa
     4741 tcttcaaatc tgttacggtt gtaatcttca gatttgagta ttcacctttg gccaaggcca
     4801 catcttttcc tttgatcaca aagattttac atgcatctgt caagatttcc ttctcttcat
     4861 cagaaagaga tccataaagg tccatgaagt ccttgcaacg gaatgtttga ggtgtttgtc
     4921 cctgatagag gtgagcacga tttggaatac ctgtaatgaa ttgcccattg gtactttcaa
     4981 cgatagtatc cactgcttct accactgtgt ccactgcgtc atgattttgg gcaagttgga
     5041 tattgtcctg aatcatgcga agtgtaataa atggacgaac agaatcgtgg gtaacaacga
     5101 tatcctctga agtaagcgga cgataagcat caatggcttc aatgatgttc tcaatacttg
     5161 tattgcggtc agcaccaccc tttgtaatga tgatacgttc cttataaaga ggaagatatt
     5221 tatctacaag atcttctgca tgagaaaccc agtctccatg aacaccaact acaatttttt
     5281 caatacttgg ctccaagaca aatttttcaa ttgtatgaat caaaataggt cgatcaccta
     5341 gctctaaaaa ttgttttggc aagttactga tccccatgcg tgtgccagtt ccaccggcaa
     5401 gaattcctgc ataaatcatc tattttctcc tttgtcttac taaaaaaact tattctctct
     5461 attataccac aatctagtcc tatcataaaa gaaatactgg tcctcccctt ctagaatagg
     5521 agaattatgc agttctatta ttcaaagaaa ctagtccatt tctagtaatg actaggaatt
     5581 ctgtagcaat tactaataaa tgactgcgaa attttagagt ccttcagaat aatatacttt
     5641 ccttaaagaa aacttaaaat ttaagatttg aaacttcaaa gtgattgctt ggcttactgc
     5701 ccttcatttc ttattagcta actttatgat ataatgaaaa acgaggtaaa ttgaatgaaa
     5761 agtataaaat taaatgctct atcttacatg ggaattcgtg tcttgaatat tatttttccc
     5821 atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa ctgactatgg ttacttcaac
     5881 tcagtcgaca ctattttgtc atttttcttg ccctttgcaa cttatggtgt ctatagctac
     5941 ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag atcttaacag aaccttttct
     6001 agtctttttt atttgtgcat cgcttgtacg attttgacca ctgctgtcta tatcctagcc
     6061 tatcctctct tctttactga taatccaatc gtcaaaaagg tctaccttgt tatggggatt
     6121 caactcattg cccagatttt ttcaatcgaa tgggtcaatg aagctctgga aaattacagt
     6181 tttctctttt acaaaactgc cttcatccgt atcctgatgc tggtctctat tttcttattt
     6241 gttaaaaatg aacacgatat tgttgtctat acacttgtga tgagtttatc gacgctgatt
     6301 aactacctga ttagttattt ttggattaaa agagacatca aacttgttaa gattcaccta
     6361 agtgatttta aaccactctt tctccctctg acagccatgt tagtctttgc caatgccaat
     6421 atgctcttca cttttttaga tcgcctcttc ctcgttaaaa cagggattga tgtcaacgtt
     6481 agttactata ccatagctca gcgaattgtg accgttatag ctggggttgt aacaggtgca
     6541 attggagtga gtgtgcctcg tctcagttac tatctgggga aaggagacaa agaagcctat
     6601 gtttctctgg ttaatagagg tagtcgaatc tttaacttct ttatcattcc actgagtttt
     6661 ggactcatgg ttttaggacc aaatgccatc ctactttacg gtagtgaaaa atatatcgga
     6721 ggcggcatct tgacctctct cttcgctttt cgtacgatta tcctggcctt agataccatt
     6781 cttggttccc aaattctctt taccaatggc tatgaaaaac gtatcacagt ttatacagtc
     6841 tttgctgggc tactcaattt gggcttgaat agtctcctct ttttcaaccg tatcgtggct
     6901 cccgaatact acttactgac aactatgtta tcagaggctt ctctacttgt tttctatatc
     6961 attttcatcc atagaaaaca actcatccac ttgggacata tctttagcta tactgttcga
     7021 tactctctct tttcactttc ctttgtagca atttatttcc tgattaattt cgtgtatcct
     7081 gtggatatgg tcattaattt gccatttttg attaatactg gtttgattat cttgctatca
     7141 gctatctctt atattagtct acttgtcttc acaaaagata gcattttcta tgaattttta
     7201 aaccatgttc tagccttaaa aaataaattt aaaaaatcat aggagtttaa aatgaaacaa
     7261 ctaaccgttg aagatgccaa acaaattgaa ttagaaattt tggattatat tgatactctc
     7321 tgtaaaaagc acaatatcaa ctatattatt aactacggta ctctgattgg ggcggttcga
     7381 catgagggct ttatcccttg ggacgacgat attgatttat ccatgcctag agaagactac
     7441 caacgattta ttaacatttt tcaaaaggaa aaaagcaagt ataagctcct atccttagaa
     7501 actgataaga actactttaa caactttatc aagataaccg acagtacgac taaaattatt
     7561 gatactcgaa atacaaaaac ctatgagtct ggtatcttta tcgatatttt ccctatagat
     7621 cgctttgatg atcctaaggt cattgatact tgttataaac tggaaagctt caaactgctg
     7681 tctttcagta aacataaaaa tattgtctat aaggatagcc ttttaaaaga ttggatacga
     7741 acagcctttt ggttgctcct tcgaccggtt tctcctcgtt attttgcaaa taaaatcgag
     7801 aaagaaattc aaaaatatag tcgtgaaaat gggcagtata tggcttttat tccttcaaaa
     7861 tttaaggaaa aggaagtctt cccaagtggt acctttgata aaacaatcga tttacccttt
     7921 gagaatttaa gccttcctgc acctgaaaaa tttgatacta ttttgacaca attttatgga
     7981 gattatatga ccctaccacc agaagaaaaa cgcttctaca gtcatgaatt tcacgcttat
     8041 aaattggagg attaggatgc aatatttaga aaaaaaagaa attaaagaaa ttcaactagc
     8101 cctgctggac tatattgatg agacttgtaa gaaacatgat attccttatt ttctcagtta
     8161 tggaaccatg cttggagcca tccgccacaa aggtatgatt ccttgggatg atgatattga
     8221 tatttccctt tatcgtgagg attatgagcg tttactgaag attattgaag aagaaaatca
     8281 ccctcgctac aaggttcttt cctacgatac atcttcttgg tacttccata atttcgcatc
     8341 gattttggac acttctactg ttatagaaga ccatgttaag tacaagcgtc atgataccag
     8401 ccttttcatc gatgtcttcc caattgatcg atttacagac ttgagcattg tcgacaagag
     8461 ctataagtat gtagcccttc gtcaactagc ttatatcaaa aaatcacgag cagttcacgg
     8521 tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg tacgctctcc ggtttgtcaa
     8581 tcctcgctac ttttacaaga aaattgatca actagtcaaa aatgctgtaa ccaacactcc
     8641 tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg aaagaaatct tcccagttga
     8701 tacctttaaa gaactgattt taactgagtt tgagggccgt atgttgcctg ttcccaaaaa
     8761 atatgaccaa tttttaaccc agatgtatgg cgattatata acaccaccat caaaagaaat
     8821 gcaagagtgg tatagtcata gcattaaagc ttatcgcaaa aactgattga gggggattat
     8881 acaaactact aagatagagg ttattcaaaa acataatttt agtagaaaat gaaatacata
     8941 ttcccacaat aaaacgcatc atatcaaggt tttt
//
LOCUS       DBEJNA010000056         8777 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEJNA010000056 DBEJNA010000000
VERSION     DBEJNA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.56"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL3JB_001935"
     CDS             complement(394..1590)
                     /gene="tuf"
                     /locus_tag="ACL3JB_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0686605.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL3JB_001936"
     CDS             complement(2501..3370)
                     /gene="gla"
                     /locus_tag="ACL3JB_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0686606.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3594..4115)
                     /locus_tag="ACL3JB_001937"
                     /pseudo
     CDS             complement(3594..4115)
                     /locus_tag="ACL3JB_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4073..5179)
                     /locus_tag="ACL3JB_001938"
     CDS             complement(4073..5179)
                     /locus_tag="ACL3JB_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0686607.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5290..5544)
                     /locus_tag="ACL3JB_001939"
     CDS             complement(5290..5544)
                     /locus_tag="ACL3JB_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686608.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5538..5780)
                     /locus_tag="ACL3JB_001940"
     CDS             complement(5538..5780)
                     /locus_tag="ACL3JB_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686609.1"
                     /translation="MVQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5884..6728)
                     /locus_tag="ACL3JB_001941"
                     /pseudo
     CDS             complement(5884..6728)
                     /locus_tag="ACL3JB_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            6962..8680
                     /locus_tag="ACL3JB_001942"
     CDS             6962..8680
                     /locus_tag="ACL3JB_001942"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0686610.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
BASE COUNT         2504 a         1796 c         1650 g         2827 t
ORIGIN      
        1 ttgatttcat attactattg tataatgctt tttgatttta gtctagtatt atactcttcg
       61 aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg acttcgtcag
      121 ttctatctac aacctaaaaa cagtgttttg agcagtctgt agctaacttt ctatagtaaa
      181 atgaaataag aacaagacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
      241 gaagtagatg tgtactattc tagtttcaat atattatagt ttgctctttg attttcattg
      301 agtattagtt caatatctaa aaaaagaacc ttgccaagca agattctttt agtgtctgac
      361 ttaaataatt gttcttctgg gaactaaatc gaattaagct tcgatttctg taaccatacc
      421 tgaaccaaca gtacgtccac cctcacggat agagaatgta gtaccttgtt ctacggcgat
      481 tgggtgaatc aactcaacgt cgattgtcac gttatcacca ggcattacca tttcagtacc
      541 tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt gtggacggta
      601 gttgttgaag aatggagtgt gacgtccacc ttcttcttta gtaaggatgt agacttcacc
      661 tttgaattta gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc cacgttcgat
      721 ttcatcacgt tgaacaccac gaagaaggac acctacgtta tctccagcaa gaccttcgtc
      781 aagttgttta cggaacattt caacaccagt aacaactgct ttttgagttt cttctttgat
      841 accaacgatt tcgatttcgt cgttgacttt aacgatacca cggtcgatac gtcctgaagc
      901 aactgtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca atggtttgtc
      961 agtgtcacgt tctggttctg ggatatactc atcaactgtg ttcatcaatt ccataacgat
     1021 gtcttcgtat ttagagtcac cttcaagagc tttaagtgct gaaccttgga taactggaag
     1081 atcgtcacct gggaagtcgt attctgacaa taggtcacgg atttccattt caaccaattc
     1141 aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa ggtgtttaac
     1201 accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc cgtcagttga
     1261 agctactaca aggatagctc cgtccatttg agcagcacca gtgatcatgt ttttaacgta
     1321 gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac
     1381 gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct ggagcagcat cgatagacgc
     1441 atagtcttta ggttggttaa ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc
     1501 tgcagttagg gtagttttac cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg
     1561 tttactacga tcgtattttt cttttgccat ttgagtaaaa gcctccaata aaatatattt
     1621 tatagataga cagtaggcaa tacagtctaa ctttccttac tattttatca aatttcagct
     1681 aaattgcaag tgttttacaa cgtttttgtg aattattctt ggtaaaaatt taactaatta
     1741 atagaaagta ctaaatagac ttatccttca aggagttttc agcattatcc atccactcac
     1801 ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga atagggcaaa
     1861 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct
     1921 agtttcaatc tactatacaa cctcaaaact gtgttttgaa caacctgcgg ctagcttctt
     1981 agtttgccct ttgattttca ttgagtataa aattgcagat aaaacgataa caatcatagg
     2041 actcagcaga gtcaatgtag gtcgaagaat agccccccta atcgcttatt ttatagcaaa
     2101 atgaaataga aactgaacat tttgttgagg aaggtaaatc aattcctcac aatgtttgag
     2161 aaagaaggga ggactattcc aacttcaacc cactataaag cagacttaca agatagggaa
     2221 cccatctccg ataatatata gtagaatgaa aactgcacaa tttgattgga gaattcaaac
     2281 caatttctaa caatgtttta gaaacaaggg tctattattt caactgcaac ctactatagc
     2341 ccattgaagc tggaatagcc cactgagact tctaaaccac tgctggagag gagtttgttt
     2401 agagtttctt tcatttccct aaaaaatcaa aaagagagaa ccagtctgat cctctcttac
     2461 ttatagatgg tgctcactca aatgttaaag gagctatttc ttagagataa aggaatttga
     2521 atacagctac tgccgcaatt gctgctgcga taggtgctac tactggtacc caagaatacc
     2581 accattttga atcgccttta tgctcaccaa gaactgattt tggaaggaaa gcatgaagga
     2641 gacgtggtcc caagtcacgg gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg
     2701 ttaccaaagc cataacgagg aatccaagtg ccaagtgagc cacagaaagt cctgaagcag
     2761 tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt
     2821 ctattgcctt ttgtttcatg aattgaagca cttcagcacc aaagaagttt ttagtcaaac
     2881 caagagctgc aaagaacaaa acaaatgaac caacaaactc attaatcaaa ccattgacag
     2941 ttgctgcata gcgactttct tttgtaccat ggtcaatact tgaaatagtt gagaaagttc
     3001 ccaagatgtt atttgggttt tcagttttca agtagaatgg acggtatgtt gccacaacta
     3061 aggcttggcc aaagatagcc cccaagactt gcgcgataat gtaaggtacc acttgtgccc
     3121 aagggaaaag accgctaact gcaagcccta gagtgaaagc agggttgatg tgattcccag
     3181 atacgttacc aaacatcaag gctgggatca taacccccat accataacca acagcgatga
     3241 cgatccagcc actttggtga cctttcgtac ctttaagttc aacgttggca actgcaccat
     3301 tcccaagaat gatcaaaatg gcagttccca aaaattcagt ggcatacttc agtgcccatg
     3361 tgaaatccat ttgctagatt ctccttaaaa ttttttagat attccttatt ttatcaattt
     3421 ttaccctatt tagcaactga tttctggaaa tatttttaaa aaaataggat tcatagtttc
     3481 ccagttcaac ggacttgtaa gcgtttttat tcttcacgaa agacctcgtt ctcaaaacca
     3541 ggaaaaaagc ccacatctgt gagcttttcc ttgttcctag attctaaaat ctattatttt
     3601 tcatcttctt ttttcttgaa gaatcctaat cctagaccag ctaacaaggt catgatacca
     3661 gcactagcca aggtagcatt agcttctgta cctgtgtttg gcaattcctc tctcttacct
     3721 gtctcataag tcggaacttc tgggtctgga ttcactggag tttcagtttt tggagtacct
     3781 ggttctggag ttggtttatc tggtgttgat aaacggtcat accttaccgt tatttcttta
     3841 tcactagagt ctgacgtaac ttcttgtgat taaactgttg gaatatctgg agctttgtac
     3901 ttgtcaatct taccagatat aacctcgtcc cagtttcctg ttgtccattc accgtaggtt
     3961 acaactcccg tgaccttgtt ctcagttttt gtacggctta aggttacagg ttgaacaaca
     4021 tcttctttta cattttggtt cgtaacttta tcaacgtaat gaatgatacg cgttatagtc
     4081 ttcgtctcag tagaggttgc tgttttggga accactgttt cctcaacatt ctcacggtag
     4141 taatagtcaa ctgttgcacc gtcttctggt acgcatttgc aggagttgct accaaggtgt
     4201 atgttgtttt ccttgtgata actcggtctt ctttgtcctc agttgttgtt ttcccttcaa
     4261 tagtttttga ttctgtggta tactcagaac ctatcgctaa atcagctttt ataacagact
     4321 ctgccaactt ctcttggcta ccttctttat agtaattggc tgttactgta acagtggttg
     4381 gcgcttcgct ttctctataa actaaggtca ctgttctacc ttcgcttaca atattcccag
     4441 ttaaacttgc agaatttgta tctacttctt taaaagtata atattttccg tcagtagtag
     4501 tcatgctact gagtttttta tctgtgacat tgtagctggt accaatcagt tgttttttat
     4561 tggtaatgta ggttccgtca ctttcttttt ctccaattcc agtatcattt ttcaatgata
     4621 gcaaacgccc ttgttcatca acatagcgaa ctttcacatt ttctgagatt agttctgcca
     4681 attctgaagt ttttttcttt ttcttgattt cttcggttat tttccctttc tcttcttcgg
     4741 gaatatttag ttttggaatg attttttcaa caacggttcg tgatggttcc acagtatctt
     4801 ggatgactga aaagtcagct agaattggga gattatactg aacacggtga ctttgagtgt
     4861 ttactcctac tctttcatta ttctctgaaa atacttgtac ggtataagaa acaacatctt
     4921 ttcctaatag aacatcccca gtagagaaat agccgccttt tcctagtttg ctatctccag
     4981 agcccacttc tttcctaatc ttatcagata gttttttacc agtcagtaca ttcgttcgca
     5041 caatcccttt gtctacccct acaaagtggg agaacttttt gaactcttca gaaccagatc
     5101 tagcccaacc attattaagg gcatttgctt ttgtatttgt attctctctc aaaagtttgg
     5161 cgattagaat tatattcatc ggcacttaga gttgctgcta tatctgactc ttgaatacca
     5221 acttccttac taccatttct agcggcagta tatgtgtatt tatctgtttc tacttctagc
     5281 tgattatcct taacatgata ggtaattttc tcctggtata agagtcttca gtagtttata
     5341 tgctctgtca tcatctttag ctttagaagc agctgagttt agccaagttg gggtattagg
     5401 agtatcttta tcagcctgtt tcaagacatt attcaagtca tttgctagcc tattggttgt
     5461 cctcactgtg aaagttttct tccagtctga accactttta ttagacttag atatgctcat
     5521 gaaatcctgg tcaacattca acacaatatc gccttgtttt ttagcatctt ccgttgcttc
     5581 tgcttcaaat tgatcatgga gtttttgttg ctctggtgta tagttttttt atttacacga
     5641 tttaatgtac tattttttat tttagtatta agaactccat taatacgatt tttaaactct
     5701 gcttcaaaaa atcccttaat ttgttggtgc gcaagttcaa cattcaaacc ttttttatac
     5761 aagtcttcat tctgaacgat ttcggctaca cggtgaatgg tttgattgta taccgtcttc
     5821 tcttaaccag cagtatcctt agttttaatg actactcgat aggttccttt agaaccgtta
     5881 tagtcatcta gttttaaaaa agcattccaa acattcaaaa atagttggaa cttcccttaa
     5941 taaatccgtc actttctttt tcaagatagc ccaagcttgc tcaataggat tcaaatccgg
     6001 tgaataaggt ggtagaggta agaaaaagtg tttatcttgg atgcagagtt catccaaaat
     6061 gttcttggga tgaaaaccag cattgcccat gacaataaca tgaggtgtct tcaaagcagg
     6121 taggagttgc gttttgaacc actccacaaa gaaatcgctt gtcatgcttt tcttgtaaat
     6181 catgggagct ataaactctc cgtctacttg tcctgcaaca attgaagttc gctcaaaacg
     6241 acgtccgcta atcttttcat agactttctc ccctctagga gcccctgcat aaggacgata
     6301 gagatagcgg tcgattcctg tttcatcaat ataaacaggt gctaggtgct ttaaactatt
     6361 aaaattctta agaaataagg ctacttttct gggtcttgtt ccttaaagct cgtcatcttt
     6421 ttttaaagtg accttaatct gctttaaagc tgcccatact gaaggaacag cacaatcaaa
     6481 atgtgccgca atttcccgta aaaaagcatc tggatgagcc tctacaaagg ctttcaattc
     6541 ctctaaagga atctttcggt ttttgacgac tcgctttttc ctctctatgt gttcttgttc
     6601 acgtctttct tttcccacgt gaagagagtt ctgacgccaa caccaaaaaa cttggctgcc
     6661 tcgacatggc tgtgcccctc tttgatgtaa tctaatgctc gctgtttaaa atcagtacta
     6721 tatgccatag ctttattata atatgcttgt ttaaaactaa gtaactatat caatgttttg
     6781 ttatgagaag acttactttt tttactgaaa ttgaattttt cctagcctca acatcatata
     6841 accccaaaat tcaatctgac ctggtttgaa gagattttcg aagcagataa ggttttacta
     6901 aaactaaaaa aaatgatata atcaaactga ttaaatgttt taaaaataaa ggagaatttg
     6961 aatgtcttac caagaaaatt accagaaatg ggttgatttt gtggagcttc ctgactacct
     7021 tcgtcaagat ttggaaaata tggacgaaaa aactaaggaa gatgccttct atacaaatct
     7081 tgaatttggt actgcaggta tgcgtggctt ggttggtgct ggtacaaacc gtatcaacat
     7141 ctacgttgtt cgccaagcta ctgaaggatt ggctcgtttg attgagtcaa aaggtggaaa
     7201 cgagaaagaa cgcggtgtag caattgccta cgatagccgt cacttctcac ctgagtttgc
     7261 ctttgaatct gcggcagttc ttgctaaaca cggcatcaaa tcttacgtat ttgaaagcct
     7321 tcgtccaact ccagaactat catttgcagt tcgtcatctc aactgtttcg caggtatcat
     7381 ggtcacagcc agccacaacc ctgctccatt taacggttac aaggtttacg gtgaagacgg
     7441 tggacaaatg cctccacacg atgcggacgc tttgactact tatatccgtg caatcgaaaa
     7501 cccatttgca gttgaagttg ctgatgtgga aactgaaaaa gcttctggct tgattgaagt
     7561 tatcggcgaa gctgttgaca tagaatacct taaagaggtt aaggacataa acatcaaccc
     7621 agccttgatt gaagaatttg gtaaagacat gaagattgtc tacacaccac ttcatggtac
     7681 tggtgaaatg ttggctcgtc gtgctcttgc ccaagcagga tttgactctg ttcaagttgt
     7741 tgaagcgcaa gcaactgctg acccagactt ctcaactgta acatctccaa acccagaaag
     7801 ccaagcagcc tttgcccttg ctgaagaact tggtcgtcaa gttggtgcag atgttcttgt
     7861 cgcaactgac ccagacgctg accgtgttgg tgttgaagtt cttcaaaaag atggtagcta
     7921 cctcaacctt tcaggtaacc aaatcggtgc tatcatggct aaatacatct tggaagctca
     7981 caaaaacgct ggaactcttc ctgaaaatgc cgctctctgc aaatctatcg tttcaactga
     8041 cttggtaacg aagattgctg aaagctacgg cgcaactatg ttcaacgtct tgacaggttt
     8101 caaatttatc gctgaaaaaa tccaagaatt cgaagaaaaa cacaaccaca cttacatgat
     8161 gggatttgaa gaaagcttcg gttacttgat taaaccattt gtacgtgata aagatgccat
     8221 ccaagccgtt cttgtcgttg ctgaacttgc tgcctactac cgttctcgtg gtttgacact
     8281 tgctgacggt atcgaagaaa tctataaaga atatggctac tacgcagaaa aaacaatctc
     8341 tgttactctt tcaggtgtcg atggtgctga acaaatcaaa gcgattatgg ctaaattccg
     8401 caacaatgct ccaacagaat ggaacgcaac agctatcact gtcgtagaag acttcaaggc
     8461 acaaactgct actgttgctg acggtactgt tacaaacttg acaactcctc caagtgatgt
     8521 gttgaaatac acacttgctg acggttcatg gattgccgtt cgcccttcag gtacagaacc
     8581 aaaaatcaag ttctacattg cagttgtagg ggaaaccaac gaagaatcac aagctaagat
     8641 tgctaacatc gaagcagaaa tcaatgcatt tgtaaaataa agacctataa aagatggctt
     8701 tttgtcaact gtagtgggtt gaaaaaaagc taagcttgag aaaggacaaa tttcgtcctt
     8761 tcttttttga tattcag
//
LOCUS       DBEJNA010000057         8540 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEJNA010000057 DBEJNA010000000
VERSION     DBEJNA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.57"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..299
                     /locus_tag="ACL3JB_001943"
     CDS             <1..299
                     /locus_tag="ACL3JB_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686611.1"
                     /translation="NRLHNIYKGFTHYKYYRAENSHLIYADYFEMKLKKLLKDDTKVF
                     EKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(653..1186)
                     /locus_tag="ACL3JB_001944"
     CDS             complement(653..1186)
                     /locus_tag="ACL3JB_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0686612.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1275..2051)
                     /gene="recX"
                     /locus_tag="ACL3JB_001945"
     CDS             complement(1275..2051)
                     /gene="recX"
                     /locus_tag="ACL3JB_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0686613.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2089..3456
                     /gene="rlmD"
                     /locus_tag="ACL3JB_001946"
     CDS             2089..3456
                     /gene="rlmD"
                     /locus_tag="ACL3JB_001946"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0686614.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYNEAVKALDVNKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDIPYIQSVDMFPHTARTEAVVKLIKK
                     IRKSS"
     gene            3506..3577
                     /locus_tag="ACL3JB_001947"
     tRNA            3506..3577
                     /locus_tag="ACL3JB_001947"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3539..3541,aa:Glu,seq:ttc)
     gene            3830..5375
                     /locus_tag="ACL3JB_001948"
     rRNA            3830..5375
                     /locus_tag="ACL3JB_001948"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            5427..5499
                     /locus_tag="ACL3JB_001949"
     tRNA            5427..5499
                     /locus_tag="ACL3JB_001949"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5460..5462,aa:Ala,seq:tgc)
     gene            5624..8525
                     /locus_tag="ACL3JB_001950"
     rRNA            5624..8525
                     /locus_tag="ACL3JB_001950"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         2585 a         1617 c         2090 g         2248 t
ORIGIN      
        1 aaaataggct ccataatatc tataagggat ttacccacta caaatattat agagccgaaa
       61 attcacatct aatatatgca gactactttg aaatgaaatt aaaaaaatta ttaaaggatg
      121 acacaaaagt ttttgaaaaa tctacattca aatttgtaga aggatataaa atatacctga
      181 cagaatctaa agaatctgga attaaacaaa tggacaatgt cataaaatat tttgagttta
      241 ttgaatctaa aagtattgct ttatattttc aaaaacgatt aaatgagctg atagattaaa
      301 tagcattttc tctgttgaga tattgttttt aaaatattgt actaaatgat tgatgctatg
      361 tggaaataca aaaaaatgtt tttgatacga agttgacctg tattttttat actaatcatt
      421 ttcgtatttt ttgtattaaa cgatataagt ttgttgtaaa cttacaagga ataaagacat
      481 taaaaaataa cagtatatct atttgtttta tatattttac gaattctgca taaatctctt
      541 tctagtaatg tgttgtaact ctgctataat agatttattc ctttttgtgt ttacacaatt
      601 tattttatac taccaaaaaa ggtcaggatt ttgttcctga cctttgacaa ctttaccgat
      661 tctttagttc tacatagcgc ttgtaccaaa tgtttacata ggcttctgag aaaggaccac
      721 gtccattgtt aatccaatca acaagaattt tgacatgttc ttttaaaata tagtccaagt
      781 catcagaata attcattttg cgtttgtgac gctcgtactc ttcaacgtcc aagagacgtt
      841 tttccccatc tgtaaaaatt ttaacatcca aatcgtaatc aatatacttc agtgcttctt
      901 catccagata gtaggggcta gccatattgc aatagtaaga agttccatta tcacgaatca
      961 tggcaatgat attaaaccaa tatttcttgt gaaagtaaac aatagccggt tctcgagtga
     1021 cccaacgacg accatcactt tcggtaacaa gtgtatgatc gttgacacca ataatggcgt
     1081 tttctgttgt ttttagtacc atggtgtccc gccaagttcg gtggagactc ccatcatgct
     1141 tataactttg aattgtaata aagtcgcctt cttttggaag cttcataact aaccaacttt
     1201 ctacaattta taagtttatc atttactatt gtaccataaa attacccaaa atctgtgaat
     1261 ttcacttgga aatattaaag atattctcta agagcgcttg ctatatccga aaaatcgtag
     1321 ccctttcgtg ctaaaacttg agttaaacgc tgcttcagtt cgtatccttc atactttcgg
     1381 gcatacttag tatattgctt atcaagttcc ttgaagatga gttcctgagt cgtttcttca
     1441 tcaacttgac tatccaattc gtcaaaggca attttagcat caaaataaga gaagcccttg
     1501 ttagtcaagt tctggataat cttatcttgc agggcacgag ctggaagttt tccctcatat
     1561 tttttcaata gtttattggc tacacgttga gcaacttccg aaaaatcaaa atcattcaag
     1621 atttcttcta tagtagattt tgaaattcct ttttgtgcta atttctgagt cagtacataa
     1681 ggtcccttgt ctcctgaaag ttgattggca ttgatgatag cataagcgta ctggctatca
     1741 ttaatccact tctcttcttt aagattagca atgacttgag aaacgatgtt ttcattaata
     1801 tcatattttt tcagatattc tctgacctct ttttcagtac gtgctttaaa ggataagtgg
     1861 tagagggcca gattcttacc ataagaaaat tgagcaaagt cttgaatctc tttcaattcc
     1921 tcttcgctta tcaccttatc tctcgataac ataaaacgaa caattgtgtc ttcggtgata
     1981 tagcatttgt cgccattatc aagctccatc agatagagtc tttttttctt ttcaagtttt
     2041 gtgattttca tagctctatt ataactcaaa atgtgataag ataggggtat gaatctgaaa
     2101 gtgaaacaaa aaataccatt aaaaatcaag cgcatgggaa ttaacggtga gggaatcggc
     2161 ttttaccaaa aaacattagt ctttgtacca ggagctctca aaggcgaaga tatctattgt
     2221 cagattactt ctattagacg caactttgtt gaagcaaaat tactgaaggt caacaagaag
     2281 tctaaatttc gaattgtgcc atcttgtact atttataatg aatgcggagg ctgccaaatc
     2341 atgcacctgc attatgataa gcagctggag ttcaagacgg acttacttca tcaagcgctg
     2401 aaaaaatttg ctcctgcagg atatgaaaat tatgaaattc gtccaactat tggaatgcag
     2461 gaaccaaaat attacagagc taagttacaa tttcagactc gaaaatttaa aaatcaggtc
     2521 aaggcgggct tatatgcaca aaactctcac tatttagtag agttgaaaga ctgcctggta
     2581 caagataagg aaacccaagt gattgctaat cgcttagcag aattacttac ttatcaccag
     2641 attccaatca cggatgagag aaaagttcta ggtgtccgta ctattatggt ccgacgcgcg
     2701 agaaagaccg gacaggttca gattattatt gttacaaacc gccagcttaa tttaactcaa
     2761 ttggtaaaag agttggttaa agatttccca gaagttgtga cagtagctgt taatacaaat
     2821 acagctaaaa ccagtgagat atatggtgaa aagacagaga ttatctgggg gcaagagagt
     2881 attcaagaag gtgtactcaa ttatgaattt tcactatccc ctcgagcttt ttatcaacta
     2941 aatcctgaac aaacagaagt tctttataac gaggcggtaa aagccttgga tgttaataaa
     3001 gaagaccatt tgattgacgc ttattgtgga gttggaacga ttggttttgc ctttgcaaag
     3061 aaagttaaaa cacttagagg tatggatatt attccagaag ctattgaaga tgctaagcga
     3121 aatgctaaaa gaatgggatt tgacaacaca cattacgaag caggaacagc ggaagagatt
     3181 attcctcgct ggtataagga aggctaccga gcagatgctc tgattgtgga cccaccacgt
     3241 acaggtctgg atgataagtt attagatact attcttacct atgtaccaga aaaaatggtc
     3301 tatatttctt gcaatgtttc aactttggca agggatttgg taaggttagt agaagtctat
     3361 gatatccctt atattcagtc ggtcgatatg tttccacaca ctgctcgaac tgaagctgtt
     3421 gtaaaattaa ttaaaaaaat tagaaaaagt agttgacaaa acataaaaag gctgtataat
     3481 agtaagagtt gaaaataaca actcaggtcc gttggtcaag gggttaagac accgcctttt
     3541 cacggcggta acacgggttc gaatcccgta cggactatgg tatgttgcgg ttggaccact
     3601 tgatgaaaaa aagtttaaaa aagcttaaaa atcttcaaaa aagtgttgac aagtgaaagt
     3661 ggctgtgata tactaatata gttgtcgctt gagagaagca agtgacaaag acctttgaaa
     3721 actgaacaag acgaaccaat gtgcagggcg ctacaacgta agttgtagta ctgaacaatg
     3781 aaaaaaacaa taaatctgtc agtgacagaa atgagtgaga actcaaactt ttaatgagag
     3841 tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag tagaacgctg
     3901 aaggaggagc ttgcttctct ggatgagttg cgaacgggtg agtaacgcgt aggtaacctg
     3961 cctggtagcg ggggataact attggaaacg atagctaata ccgcataaga gtagatgttg
     4021 catgacattt gcttaaaagg tgcacttgca tcactaccag atggacctgc gttgtattag
     4081 ctagttggtg gggtaacggc tcaccaaggc gacgatacat agccgacctg agagggtgat
     4141 cggccacact gggactgaga cacggcccag actcctacgg gaggcagcag tagggaatct
     4201 tcggcaatgg acggaagtct gaccgagcaa cgccgcgtga gtgaagaagg ttttcggatc
     4261 gtaaagctct gttgtaagag aagaacgagt gtgagagtgg aaagttcaca ctgtgacggt
     4321 atcttaccag aaagggacgg ctaactacgt gccagcagcc gcggtaatac gtaggtcccg
     4381 agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggttagataa gtctgaagtt
     4441 aaaggctgtg gcttaaccat agtaggcttt ggaaactgtt taacttgagt gcaagagggg
     4501 agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac accggtggcg
     4561 aaagcggctc tctggcttgt aactgacgct gaggctcgaa agcgtgggga gcaaacagga
     4621 ttagataccc tggtagtcca cgctgtaaac gatgagtgct aggtgttaga ccctttccgg
     4681 ggtttagtgc cgtagctaac gcattaagca ctccgcctgg ggagtacgac cgcaaggttg
     4741 aaactcaaag gaattgacgg gggcccgcac aagcggtgga gcatgtggtt taattcgaag
     4801 caacgcgaag aaccttacca ggtcttgaca tccctctgac cgctctagag atagagtttt
     4861 ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt
     4921 gggttaagtc ccgcaacgag cgcaacccct attgttagtt gccatcattc agttgggcac
     4981 tctagcgaga ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa atcatcatgc
     5041 cccttatgac ctgggctaca cacgtgctac aatggctggt acaacgagtc gcaagccggt
     5101 gacggcaagc taatctctta aagccagtct cagttcggat tgtaggctgc aactcgccta
     5161 catgaagtcg gaatcgctag taatcgcgga tcagcacgcc gcggtgaata cgttcccggg
     5221 ccttgtacac accgcccgtc acaccacgag agtttgtaac acccgaagtc ggtgaggtaa
     5281 ccgtaaggag ccagccgcct aaggtgggat agatgattgg ggtgaagtcg taacaaggta
     5341 gccgtatcgg aaggtgcggc tggatcacct cctttctaag gataaggaac tgcgcattgg
     5401 tcttgtttag tcttgagagg tcttgtgggg ccttagctca gctgggagag cgcctgcttt
     5461 gcacgcagga ggtcagcggt tcgatcccgc taggctccat tggtgagaga tcaccaagta
     5521 atgcacattg aaaattgaat atctatatca aatagtaaca agaaaataaa ccgaaaacgc
     5581 tgtagtatta ataagagttt atgactgaaa ggtcagaaaa taaggttaag ttaataaggg
     5641 cgcacggtgg atgccttggc actaggagcc gacgaaggac gtgacaaacg acgatatgcc
     5701 ttgggtagct gtaagtaagc gatgatccag ggatttccga atgggggaac ccaacaggta
     5761 atacctgtta cccacatctg ttaaggatgt gaggaggaag acgcagtgaa ctgaaacatc
     5821 taagtagctg caggaagaga aagcaaaagc gattgcctta gtagcggcga gcgaaacggc
     5881 agaagggcaa accgaagagt ttactcttcg gggttgtagg actgcaatgt ggactcaaag
     5941 attatagaag aatgatttgg gaagatcagc caaagagagt aatagcctcg tatttaaaat
     6001 agtctttgta cctagcagta tcctgagtac ggcgggacac gtgaaatccc gtcggaatct
     6061 gggaggacca tctcccaacc ctaaatactc cctagtgacc gatagtgaac cagtaccgtg
     6121 agggaaaggt gaaaagcacc ccgggagggg agtgaaatag aacctgaaac cgtgtgccta
     6181 caacaagttc gagcccgtta atgggtgaga gcgtgccttt tgtagaatga accggcgagt
     6241 tacgttatga tgcgaggtta agttgaagag acggagccgt agggaaaccg agtctgaata
     6301 gggcgcctta gtatcatgac gtagacccga aaccatgtga cctacccatg agcaggttga
     6361 aggtgcggta agacgcactg gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac
     6421 ttgtgggtag cggagaaatt ccaaacgaac ttggagatag ctggttctct ccgaaatagc
     6481 tttagggcta gcgtcgacat tagagattct tggaggtaga gcactgtttg ggtgaggggt
     6541 ccatcccgga ttaccaatct cagataaact ccgaatgcca atgaattatg gtcggcagtc
     6601 agactgcgag tgctaagatc cgtagtcgaa agggaaacag cccagaccac cagctaaggt
     6661 cccaaaataa ttgttaagtg gaaaaggatg tggggttgca cagacaacta ggatgttagc
     6721 ttagaagcag ctattcattc aaagagtgcg taatagctca ctagtcgagt gaccctgcgc
     6781 cgaaaatgta ccggggctaa aacaatttac cgaagctgtg gataccttta taggtatggt
     6841 aggagagcgt tctatgtgtg atgaaggtat accgtgagga gtgctggaac gcatagaagt
     6901 gagaatgccg gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg
     6961 tttccagggg aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt
     7021 gtatccgatg gacaacaggt tgatattcct gtactagagt atgtagtgat ggagggacgc
     7081 agtaggctaa ctaaagcaga cgattggaag agtctgtcta agcagtgagg tgtgaattga
     7141 gtcaaatgct taattctata acattgagct gtgatgggga gcgaagttta gtagcgaagt
     7201 tagtgacgtc acactgccaa gaaaagcttc tagcgtttaa acatactcta cccgtaccgc
     7261 aaaccgacac aggtagtcga ggcgagtagc ctcaggtgag cgagagaact ctcgttaagg
     7321 aactcggcaa aatgaccccg taacttcggg agaaggggtg ctgactttaa gtcagccgca
     7381 gtgaataggc ccaagcaact gtttatcaaa aacacagctc tctgctaaat cgtaagatga
     7441 tgtatagggg gtgacgcctg cccggtgctg gaaggttaag aggagtgctt agcgtaagcg
     7501 aaggtatgaa ttgaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg
     7561 aaattccttg tcgggtaagt tccgacccgc acgaaaggcg taatgatttg ggcactgtct
     7621 caacgagaga ctcggtgaaa ttttagtacc tgtgaagatg caggttaccc gcgacaggac
     7681 ggaaagaccc catggagctt tactgcagtt tgatattgag tgtctgtacc acatgtacag
     7741 gataggtagg agtctaagag atcgggacgc cagtttcgaa ggagacgctg ttgggatact
     7801 acccttgtgt tatggccact ctaacccaga taggtgatcc ctatcggaga cagtgtctga
     7861 cgggcagttt gactggggcg gtcgcctcct aaaaggtaac ggaggcgccc aaaggttccc
     7921 tcagaatggt tggaaatcat tcgcagagtg taaaggtata agggagcttg actgcgagag
     7981 ctacaactcg agcagggacg aaagtcgggc ttagtgatcc ggtggttccg tatggaaggg
     8041 ccatcgctca acggataaaa gctaccctgg ggataacagg cttatctccc ccaagagttc
     8101 acatcgacgg ggaggtttgg cacctcgatg tcggctcgtc gcatcctggg gctgtagtcg
     8161 gtcccaaggg ttgggctgtt cgcccattaa agcggcacgc gagctgggtt cagaacgtcg
     8221 tgagacagtt cggtccctat ccgtcgcggg cgtaggaaat ttgagaggat ctgctcctag
     8281 tacgagagga ccagagtgga cttaccgctg gtgtaccagt tgtcttgcca aaggcatcgc
     8341 tgggtagcta tgtagggaag ggataaacgc tgaaagcatc taagtgtgaa acccacctca
     8401 agatgagatt tcccatgatt atatatcagt aagagccctg agagatgatc aggtagatag
     8461 gttagaagtg gaagtgtggc gacacatgta gcggactaat actaatagct cgaggactta
     8521 tccaaagtaa ctgagaatat
//
LOCUS       DBEJNA010000058         7868 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEJNA010000058 DBEJNA010000000
VERSION     DBEJNA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.58"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(116..391)
                     /locus_tag="ACL3JB_001951"
     CDS             complement(116..391)
                     /locus_tag="ACL3JB_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0686615.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="ACL3JB_001952"
     CDS             complement(498..1337)
                     /locus_tag="ACL3JB_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0686616.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="ACL3JB_001953"
     CDS             1479..2327
                     /locus_tag="ACL3JB_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0686617.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="ACL3JB_001954"
     CDS             complement(2420..3337)
                     /locus_tag="ACL3JB_001954"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0686618.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3816..3964
                     /locus_tag="ACL3JB_001955"
                     /pseudo
     CDS             3816..3964
                     /locus_tag="ACL3JB_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="ACL3JB_001956"
     CDS             complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="ACL3JB_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0686619.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4600..4944)
                     /locus_tag="ACL3JB_001957"
     CDS             complement(4600..4944)
                     /locus_tag="ACL3JB_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0686620.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="ACL3JB_001958"
     CDS             complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="ACL3JB_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0686621.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5310..5397)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5456..6160)
                     /locus_tag="ACL3JB_001959"
     CDS             complement(5456..6160)
                     /locus_tag="ACL3JB_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0686622.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6562..6861
                     /locus_tag="ACL3JB_001960"
     CDS             6562..6861
                     /locus_tag="ACL3JB_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0686623.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7043..7868
                     /locus_tag="ACL3JB_001961"
                     /pseudo
     CDS             7043..7868
                     /locus_tag="ACL3JB_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2493 a         1604 c         1300 g         2471 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg cactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgagataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 gttttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg caataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgttatgtat gaaaaagcaa tgcaactaac tcctgagaac tttaaattac
     3601 taattggtgc cgaaaaggta gaatttagaa tcgaggtaca cctatggctg taaaatttac
     3661 aaaatgagac aacttgggca agatgtttga agaatttcct aaactccctg atttgaagca
     3721 agtcactttc cctgatgaca aagaaaaaag ccaaaacagc aaagaaaaac tagatgactg
     3781 ctttccaaca actcccatct agtgtgcttc agactgggct atttttctct ccatctgtta
     3841 gcttggattc tcagaccgtt tcagctaaag aatatctttt cccttatcag aaggaacggc
     3901 tcaaaccatt cagacaagtg aagggatgac aagccaatat ttgaaaccag atagcagttc
     3961 ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg aaactcatat caatttttaa
     4021 cagtgttcta ttccagattc atactcaatg aaaattaaag tgcaaactag gaagttagcc
     4081 gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg tttgaatttg attttcgaag
     4141 agtatcaatc cactatacat attaaaaagt atgggtatca aaataaaaaa acaggctctc
     4201 cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt acatttcaag
     4261 gttcgggata aaaggttcaa tgaacctttt tattttgcga ttgggtaaac agaaacttgt
     4321 tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc gaacaaagta
     4381 tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg ttgacggtaa
     4441 aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag acgttttgct
     4501 tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa aagttgcaag
     4561 ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg tgataactct
     4621 ggtttggacg aactcagaag agttctccga taagtttgcc atacctaaga aaaatgattc
     4681 aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta tttcaaccat
     4741 cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg caaatttctc
     4801 aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga catctaagcc
     4861 gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc catcttcggc
     4921 tctctcaaag actgcctgta tcatgtgttc tccttaaaat taagcgttga ttgcgttgat
     4981 gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt ttttaggttt
     5041 gtacttgtaa gtaaccactt tcttttgttt tccttgtttt tcaacagttc caactacagt
     5101 agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa gaacaacttc
     5161 gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaacgtaaa ctgcttgacc
     5221 aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc tcattatgca
     5281 cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta gcatcgtggg
     5341 acgaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
     5401 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
     5461 atgaagcttt ttcttttact tttttctgcc aagaggcaaa aagcatgctg aggtaaaaaa
     5521 cgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc gtcaaatagg
     5581 ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg aatccttcac
     5641 gcaaaaaagg agtgtgcttg gttcggaaat aatctccaaa agccagcatg gtccgtttga
     5701 tattccctgt cataaaagcg ttattatagg caatacccga cacttctcca aaagcagttg
     5761 tcaccagtcc catacagaag gccaagggcg gcactagata gatattatcc acagtttgcg
     5821 gcacaaaagc aataatgatt gataagattg ccaagggaat caaggacaga ataggttttt
     5881 tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatc ataaacgcta
     5941 gcaaggtgag aaccttgtcc ctaacatccg aaacattatt tttaattaat tctactgaaa
     6001 gaaagacaac atttccagtt tgtccagcta caagggtatt cccgcgaaca ataaaagtgt
     6061 aagcatccac atatccagca caaaacgtca aaaaaagtgc taacctttta gactgacgtg
     6121 atatttttct tataggtaat aacctcattt tacctcccat tgtattttct cttagaaata
     6181 ttgtaccatt ttctttctaa aaaatcgtag gctaccattt agattttact attagcataa
     6241 aaataataat agacaactat ttatccaaaa atagatagat gtaacatgtt tgcaaacaaa
     6301 gcatacgaac ctttagtaaa atcatttcca tgaaactaga atagagccct cttagcaaaa
     6361 atcattattt taatttattt ctaatcactc cttgacataa ataactctca ccaataaaag
     6421 actatgtctt aaaaaaatgg tataataaaa tcaatacttg ggcttgatgg ctatgctact
     6481 aataacaatt aggagagaaa atcaggcact tgttaacaac aaggattatc cccttgagat
     6541 gaaaggaact ttagaaatct tatgatgaac atgcaaaaca tgatgcgtca agcacaaaaa
     6601 cttcaaaaac aaatggaaca aagccaagct gaacttgctg ctatgcaatt tgttggcaaa
     6661 tctgctcaag atcttgtcca agcgacctta actggcgata agaaagttgt cagcattgat
     6721 ttcaatccag ctgtcgttga cccagaggac cttgagactc tttctgatat gaccgttcaa
     6781 gccatcaact ctgctcttga acaaatcgat gaaactacca agaaaaaact gggtgctttc
     6841 gctgggaaat tacctttcta aaaacaagga gctagaacaa tgcttgtcga taacaaaggc
     6901 taagaaaggt gcaaaaatga ctctataata tttgtagtgg gtaaatccac tatagatatt
     6961 atggagccta ttttattgta gaaaaaaagt cccatatgac ctataatgaa aagcgacaaa
     7021 acaactcatt agaaagaatc atatggaaca attacatttt atcacaaaat tactagacat
     7081 taaagaccct aatatccaga ttttagacat catcaagaag gatacacaca aggaaatcat
     7141 cgccaaactg gactacgacg ccccatcttg ccctgagtgc ggaaaccaat tgaagaaata
     7201 tgactttcaa aaaccttcta aaattcctta tcttgaaaca actggtatgc ctactagaat
     7261 tctccttaga aagcgtcgtt tcaagtgcta tcattgttct aaaatgatgg ttgctgaaac
     7321 ttctatcgtc aagaagaatc accaaatccc tcgtattatc aaccaaaaaa ttgcgcaaaa
     7381 gttaattgaa aagatttcta tgaccgatat tgcccatcag ctttccatct caacttcaac
     7441 tgttattcgt aagctcaatg attttcactt taaacatgat ttttcttgtc ttcctgagat
     7501 tatgtcttgg gatgagtatg cttttacaaa aggaaagatg agcttcattg cgcaagattt
     7561 taacaatctc aatatcatca ctgttcttaa gggaagaaca caagctgtca tccgaaatca
     7621 ctttcttaaa tatgatagag ccgtccgatg tcgcgtcaaa atcattacta tggatatgtt
     7681 tagtccttac tatgacttag ctagacagct tcgctttcaa atttctaggc tcaggctgaa
     7741 acagtctccc agactgtttc actcccgaat gctaaaatcg ttctagatcg tttccatatt
     7801 atccaacatc tcagccgtgc tatgagtcgt gtgcgtgtcc aaatcatgaa tcagtttcat
     7861 cgaaaatc
//
LOCUS       DBEJNA010000059         7732 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEJNA010000059 DBEJNA010000000
VERSION     DBEJNA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.59"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..281
                     /locus_tag="ACL3JB_001962"
     CDS             <1..281
                     /locus_tag="ACL3JB_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686624.1"
                     /translation="EFNRLSNVFSEEHIYYAHSYASWERGTNENHNRLIRRWLPKGTK
                     KMTPKEVAFIEKWINNYPKKYLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            277..951
                     /locus_tag="ACL3JB_001963"
     CDS             277..951
                     /locus_tag="ACL3JB_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0686625.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFNI"
     gene            complement(993..2981)
                     /locus_tag="ACL3JB_001964"
     CDS             complement(993..2981)
                     /locus_tag="ACL3JB_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0686626.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFVKNDGLKGQKTLTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2983..3741)
                     /locus_tag="ACL3JB_001965"
     CDS             complement(2983..3741)
                     /locus_tag="ACL3JB_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686627.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4169..4360
                     /locus_tag="ACL3JB_001966"
     CDS             4169..4360
                     /locus_tag="ACL3JB_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686628.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4714..4986)
                     /locus_tag="ACL3JB_001967"
     CDS             complement(4714..4986)
                     /locus_tag="ACL3JB_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0686629.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5044..5493)
                     /locus_tag="ACL3JB_001968"
     CDS             complement(5044..5493)
                     /locus_tag="ACL3JB_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0686630.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(5480..7609)
                     /locus_tag="ACL3JB_001969"
     CDS             complement(5480..7609)
                     /locus_tag="ACL3JB_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0686631.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2307 a         1624 c         1509 g         2292 t
ORIGIN      
        1 cggaattcaa tcgcttgtct aatgtatttt ctgaggagca catttattat gcacattcct
       61 atgcctcttg ggaaagggga actaatgaga atcacaacag gctcattcgt agatggttac
      121 ctaagggaac caagaaaatg actcccaaag aagtcgcatt catcgaaaag tggatcaaca
      181 actatcctaa aaaatacttg gactacaagt cacccagaga agacttctgg atggctaact
      241 tgaacttgaa atttagcgtc agaaacaaat cacgaaattg attcaaattt tgcaggtcgt
      301 ttaaatatcc tgcgtgcggg tgttcttgat gctaacgatg gaattatttc cattgctggt
      361 gtggttatcg gagttgccag tgccacgacc aatatctgga ttatcttttt atcaggtttt
      421 gcggctatct tagctggtgc cttttcaatg gctggtggag aatatgtatc cgtttcaact
      481 ccaaaagata ccgaggaagc tgccgtttcg cgagaaaaac tcttgttaga ccaagatagg
      541 gaactagcca aaaaatccct ctatgctgct tatatccaaa atggagaatg caaaacttct
      601 gcccaactct tgaccaataa gatctttctt aaaaatccac tcaaggctct ggtagaggaa
      661 aaatatggga ttgagtatga agaatttacc aatccttggc acgctgccat ttctagcttc
      721 gttgcctttt tccttagaag tttgcctcca atgctgtcag tgaccatatt cccaagtgaa
      781 tatcgcatcc ctgctactgt ccttattgtc ggtgtggccc ttcttctcac tggttacact
      841 agtgccagac ttggaaagga tccgactaga acagctatga ttcggaacct tgctattggt
      901 ctcttgacca tgggagttac cttcctgctc gaacaacttt tcaacattta gaatacaaga
      961 aatacctcga ttttgaagtc gaggtatctt ttttacattt gcacaatctt gcgataactt
     1021 cttgaagtaa tcatgaaaat cagcacatag gcgatgagga agatagcgca gatagacaag
     1081 gtcacaatca acatcatagt cgtatccagt acaccaatca cttttaaaat caggctaagc
     1141 atatggtagg caaaggcgag atgtatgaag gcaaagagca aaggaaggaa gaaaacagtt
     1201 aaaacctgtt tgttgatggt ttgcttgatt tgcttttggt ccaaaccgac tttctgcaag
     1261 ataataaagc gttcacggtc ttcgtagcct tcagaaattt gtttgtagta gatgaccaga
     1321 acagttccga ccataaagat aatggatagg aaaataccga taaagaagac accaccaaag
     1381 agggcactca tctgagaact agcatctgct agattgctac cataaacata gctaccttct
     1441 gtgtctaatt gagcattaaa ttgattgagg tagttttcat actcctcagc gaccttgagt
     1501 tgttcttctt cgctggcatc tacattcata ccaccgtaaa actgattata gatagccgaa
     1561 tctgggaatt gatccaaaaa ggcttgtaaa tcaggaacaa caaggtaatt gtaatcagta
     1621 gtcaagatat taaacttatt tggaacatgg ttgacaatga aatctttatt aaattcttct
     1681 ttgacagaaa attgatgatc atttagagtt agagttttct gtcctttcag tccgtcattt
     1741 ttgacaaaga gaccgacctc atttcctgat agagacagtt tttgaccagt catattttca
     1801 taatcttttt ggtcaaatac catgaaaact gtttttggtt ggacacggtt ttgtcctttt
     1861 tcaaaaatag ttaacttggt tccttcttga ttcgcaacag caaagtaagt gtaacgaagc
     1921 acttctttct ctttaatctt ataacctttg tcacttgcaa actggctcaa gagtttgtcc
     1981 aaatcttctt tttcaacatt ttgccctgaa accccaaaat catgaggatt tagaactttt
     2041 ttaaaggatt ctgcggaatt gaaaatgctt gtcgctgctg acatggttac caaaaccatt
     2101 gttgacaaaa tagcgatagt tgctagtcca actgcatttt tcttcatacg gaaaatcagg
     2161 ttggaaacag agatgaggtt attaggttgg taatagtatt tcttgttttt cttcaagatt
     2221 tgaagaaaaa cggtaatccc tgcattgaac aaaagataag taccaaagat aaccagtaaa
     2281 acagctatga agaaggttgt taaggctgta agaggatctt ttaccgtaag ggcaagataa
     2341 tatccaatcc ctaaacttat ggaaccaaga atagtttgga gaggaaggaa gcgacctttt
     2401 ttctctccgc tagctttctc acgtgagagc tggagggcat tcatacgggc gattcgaagg
     2461 gcattcagga acatgaggcc taggaaaatc aaaccgaaga caagaagtac tgtaatgaca
     2521 actttcatct ggaaggtagc gaccagttcc accttcaatt tcatcagttt gagtaggaaa
     2581 gcgaaaatca acttgtcaaa caaggctcca ataccgattc ctgctccaac agttagaatc
     2641 ccaaatagca ctaactcctt aaaggtcata ctgattagat ggcgcttctc caagcctaac
     2701 atgccatata tacccagttc cttggaacgg tttttcatga caaaactatt ggcatagagg
     2761 acgataatgg ctgacgcaag ggtaacgaca aacataccaa atccaagtgt tgcttgaatg
     2821 gtggttcctc cacggatttc cgcaatcttg ggattgaagg ttagggagta aaagagatag
     2881 gtgatggtga ctgccaagag aacagccagt gcaaagggat agtagagctt gcggttttta
     2941 atcaagttcg ataccgctaa cttattggtt aatcgaaaca tactaattca cctcgcttgc
     3001 catgacagtc aaggtatcag agatttcttg gaacatctga cgctctgtct tctctccacg
     3061 gtagatttgg ttgtaaagaa tgccgtcttt gataaagaga acacgcttgg ccctgctagc
     3121 agctgctgtt gagtgggtta ccatgaggat ggtttgccca cgctcattga tttcattaaa
     3181 gacatcaagt aaggctgcag atgacttgga atcaagggct cctgttggct cgtccgcaag
     3241 gagaatttca ggttctgtga tgatggcgcg ggctactgct acacgctgtt tctgaccacc
     3301 agaaatctcg taagggtact tctcttgcaa ttggttgata cccagatttt cagctgtcat
     3361 caccaatttc ttcatcatct ccgttatagg tcttcttgac aagacaagcg gaagcaagat
     3421 attgtcctta acagacagag tatctagcaa gttaaagtct tggaagacaa atcctagctt
     3481 ttcacgccgg aaactagaag cctgtgaatt tttaatagtt gctgtatcag ttccatttaa
     3541 gtaaacctga ccacgacttg gtttgtccag catagctagg atattgagaa gagtggattt
     3601 accagaacca gactcaccca tgatggcaac atagtcaccc ttttctacgg taaagtgaat
     3661 atccttgagg gcctctactt ggttgccctg aaaacgtgtt ttataaattt tttgaacgtg
     3721 ttttacatct aaaagtgtca tgagaatctc ctttcttaat atcccatcaa atgaaatgta
     3781 gcttgcatca tagtgcatcc cagctgaacg cgctcaattt ctttgtgact tggttttcta
     3841 gttttcttat gtaagatttg tttcatgatg ttactccttt gttctttatg agtctagttt
     3901 acatcaaaaa aagaccgctt gccataacct aaccttacaa aagagacttt aatcttacat
     3961 ttttgtaaga ttgggtgaaa tataagcaaa attacttaga aaatgatttg atttcctatt
     4021 tttaaagttg taaaatataa gtgtgaaaag gcttactttg aaaaggagga agcgggaact
     4081 aacattttag taaggttacc tagataacat accattcaat ttaacacttg caagtcgttc
     4141 aacctataag gaaagaaggt gcgctttaat gaaacacaaa gaacatatac tcatcggact
     4201 tctctatctg ctctctccat tcatcggtca gctcttagtt gaacacacac actttatcag
     4261 tacagaattt accggcactg cttatgttat ttgctggtta tcagttgtta tcagcatcca
     4321 ccatttttcc aaaaatgtat tgtctcaaca gcaaaaatag attaaaaaac tgcgtttaaa
     4381 ttactgcttt tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtcaaatc
     4441 gatttctaac aattttttag aagtataggt gtcctattct agttccaatc cactatagtt
     4501 tgtggatgaa gctggcgaaa tattattaat actattcaaa aatcaaagtg caaactatat
     4561 caacttcaca ttgccgacta aattacagcc tgcggctggc ttcctagttt gcactttgat
     4621 ttttattgag tataaaagta aaaaagcttt aaatcaagca gtttagacta ttgatttaaa
     4681 gctttttgcg tattccaaat cttttgtaaa acctcaccaa aaccagcctt cattatcgtc
     4741 aatggcttga gcttctttgc gtttacgtgg gcctgttccg tacatttctg cttcgatttc
     4801 ttccttggtt ggcatgatag aagctaggat gatatagata atcaccccaa gtccaaagtt
     4861 tgcgactgta aaaatggcaa acagaaaacg tacaagggta acatcaaagt tccacttgtc
     4921 tgacagacct gctaaaactc ctgaaatcat gcgatttcgt ctcattttat aaaacttact
     4981 gttcatgata tttcctcttt ctgctaggtt agactagtat atcacggata ggctcggctt
     5041 tcatcagtcc tcaggctgat ttactaatag caactttcct cgacaaagtc cacagcgata
     5101 gcgtttggta tcaatcctac gcttacgctg ataagtttgc tggcaggatt ggcaacgata
     5161 gagcttgatt ggcttggagt tactattggg caaggatggt acaaaccgta atccatccac
     5221 tgctttcaac agttccttaa aatcccgatc cttgtgttga tagcctttcc cttgaaaata
     5281 gaggtgataa tgacagagtt catgtcggac aattttccta aaaacgtcca accccagttc
     5341 ctgataaacc ttgggattaa aatccaaatg cccatctttg gggaaaaatc gcccacctgt
     5401 cgaacgtaga cgcctattcc actggacatg atggataaaa ggtctgccga agtcttctag
     5461 tgaaacctgc ttgacgtaat cagtcagttt catttggagc taggagagac agattaactt
     5521 tttcacgttc agtatcaatt ttcttaaccc aaacgctcac caaatctcca actgccacca
     5581 cttgactagg gtgtttgata aacttgcgac tcatatggga aatatggatg agaccgtcct
     5641 catgaattcc gatatcaaca aaagcaccga aatcaacaac gttacgcacc actccttcta
     5701 gcttttgtcc aaccactaag tccttgatat ctaggacatc ttgacggaga actggagcat
     5761 caaaggaatc acggaaatct cgacctggtt tgagaagatc tgcaatgata tctttaagag
     5821 tttctggacc aaggtctaac tcttgcgcca tttccttgac tgaaagcgac ttgagtttgc
     5881 tttgggcctc ttcattcaga tccttaatgt ccaagcattt gaagagttcc ttaacggcag
     5941 cgtaattttc tgggtgaact cctgtattat caaggatatt gctactttca gggatacgga
     6001 ggaaaccagc agcctgttca aaagccttgg cccccaaacg aggaactttc ttgatttggg
     6061 agcgtgaagt gatttttccc tcttcctcac ggtatttgac gatattttca gaaatggttt
     6121 tattgagtcc agctacgtgt gaaagaagag ctgggctagc tgtattgaca ttgacaccaa
     6181 cttggttaac cactgtatcg acaacaaagt ccagactctc agatagtttc ttctgactga
     6241 catcgtgttg gtattgaccg acaccaattg acttaggatc gattttgacc aattccgcaa
     6301 gaggatcttg caaacgacgg gcgatagaaa tggcagagcg tttttcaacg gtcaagtctg
     6361 gaaactcctg acgagcaagt tcgctggcag aatagacaga agcaccactt tcattaacga
     6421 taacatagct gacttcaggg aaatctttca gaacttccgc tacaaaagct tcactttcac
     6481 gactggccgt tccatttcca atggcaataa tctctacacc gtattgacca attaaatctg
     6541 ctaaatcttt cttggcttct tcgatttgac gagctgatgc tggtttaaca ggataaataa
     6601 cctgagttgt cagcattttt cctgttgcat ccacgacagc tagcttggca cctgtacgaa
     6661 aggctgggtc aaacccaaga accacgcgcc ctttcagtgg agcaaccaag aggagattgc
     6721 gcagattgtc agaaaaaagt tggatagctc cctcttcagc tttctcagtt aattctgtcc
     6781 gaatacgacg ctcaatagca ggcaagacct ttttcttaac ggattgctga acaacttcat
     6841 caatataagc atttttcacc ttgaaacgag tagcaaagaa ggcaagaata cggtccgtcg
     6901 catgttcaaa accgatcttc aagacaccaa gtttctcccc acgattgaga gccaaggtac
     6961 gatagccttg catagttcca actgtctctg aaaaatcata ataaatctga aaaacctgct
     7021 tttcatcaag actttcatcc ttggcttgag aagtgagttt agagtgtctc agcacttcct
     7081 gataagtcat agcacgcaat gtcacatctt ccgataaggc ttcgaccaaa atatcaactg
     7141 caccggtcaa ggcttccttg ccagtcgcaa atccttcaca gacgaacttt tcagcttctt
     7201 tctctaagtc aactatattc tgcaaaatca agcgagcaag aggaaagagt ccagcttcac
     7261 gggcaatggt tgccttggta cgacgctttt ccttataagg aagatagagt tcttcaacgt
     7321 ctgctaattt ttcggcaact aagatagctt cttccaattc cttggtcaac ttaccttgtt
     7381 cttgaatctt agctaagaca gcttccttac ggtcattgag atttgtcaga cttttatcca
     7441 aatcaataat agccttaatc gccacctcat ccagactacc agtcatgtcc ttgcgataac
     7501 gcgcgataaa gggaatagtc gccccttcag ctgtcaaact tagaacggta tcaatttgct
     7561 ttaacgtcac tcccaaatcc tgagagattt tttcatattt tttatccata aatctattat
     7621 accacaagct ggaaggcttt ctccaatcct tttcatactc aatgaaaatc aaaaagcaaa
     7681 ctaggaagct agccgcaggc tgctcaaaat actgttttga ggttgtggat aa
//
LOCUS       DBEJNA010000060         7678 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEJNA010000060 DBEJNA010000000
VERSION     DBEJNA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.60"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..227
                     /locus_tag="ACL3JB_001970"
                     /pseudo
     CDS             1..227
                     /locus_tag="ACL3JB_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            380..580
                     /locus_tag="ACL3JB_001971"
     CDS             380..580
                     /locus_tag="ACL3JB_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686632.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            605..1022
                     /locus_tag="ACL3JB_001972"
                     /pseudo
     CDS             605..1022
                     /locus_tag="ACL3JB_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
     gene            1253..1960
                     /gene="ccdA2"
                     /locus_tag="ACL3JB_001973"
     CDS             1253..1960
                     /gene="ccdA2"
                     /locus_tag="ACL3JB_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0686633.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQERAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1971..2528
                     /gene="sdbB"
                     /locus_tag="ACL3JB_001974"
     CDS             1971..2528
                     /gene="sdbB"
                     /locus_tag="ACL3JB_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0686634.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDVPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2902..4293
                     /locus_tag="ACL3JB_001975"
     CDS             2902..4293
                     /locus_tag="ACL3JB_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0686635.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4436..5353
                     /gene="adcAII"
                     /locus_tag="ACL3JB_001976"
     CDS             4436..5353
                     /gene="adcAII"
                     /locus_tag="ACL3JB_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0686636.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5361..>7678
                     /locus_tag="ACL3JB_001977"
     CDS             5361..>7678
                     /locus_tag="ACL3JB_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0686637.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEEPSPQLTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHP
                     ERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWI
                     KKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRM
                     PYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHP
                     NERPHSDNGFGNASDHVRKNKADQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT         2388 a         1421 c         1626 g         2243 t
ORIGIN      
        1 tcgatactta tttttatcga gaatatggtc gctcattaaa aggtcagtta agaagaggca
       61 aagtatctgg aagaagatat cagaggattt ctttggttgc aggtctaaca aatggtgagt
      121 taatcgttcc aatgacttac gaagagacga tgacgagcga cttttttgaa gcttggtttc
      181 agaagttttt cttaccaaca ttaaacacac catcggttat tatagtaaaa tgaaataaga
      241 acaggacaat caaatcaatt tctagcaatg ttttagaagt ccatatgtac tattctagtt
      301 tcaatatacc ataactgctc ctagtcaacc tgcaagtcct gtcccagctc caagctcagc
      361 tccgactcaa gatcctagag tggtagtaag cgcttcggct agctcaacga gcacacaagc
      421 tcaagagcaa gttgacaagt ctgaacttcg tgccttgagt caagagttag accaacgctt
      481 gaaagctttg gcaacagtat ctgatccgaa aatcgatgca accaaggctg tcctcctaga
      541 tgctcaaaaa gctccggaag atagtgcctt gacagagtaa ggtctgcata ctgcagtaga
      601 gtctgtgaag actgccttgg actctctcaa agatgtgatg gcaaatgcta gcgacagcaa
      661 gcctacacag gacaagaagg atgcaaaaca aggaacggaa gatagtaagg attcagataa
      721 gatgactgaa acaaactcag ttccagcagg agtgattgtg gtcagtctac ttgccctcct
      781 aggcgtgatt gccttctggc taattcgccg taagaaagag tcagaaatcc agcaattaag
      841 cacggaattg accaaggttc taggacagct agatgcagaa aaaagcggat aaaaaagtcc
      901 ttgccaaagc ccaaaacctt ctccaagaaa cccttgattt cgtgaaataa gaaaatggct
      961 cagcagagac agaaactaaa ctagtagagg agcttaaagc aatccttgac aaactcaagt
     1021 aaaacatgat ttatgaaatg tcagacctaa aagacatttt cgttcacaaa agcagcgacg
     1081 agtaatcctt gtcgttgctt tttggctatt ttgggggata agatccgcct tgactagcaa
     1141 aagaaaagat tggtccaata gtgcccgata cgattttgcg tagcagaaag cttacaaata
     1201 aaattgaata tagtaaaata ggattagaat tattaagaaa gttggttctt tattggaaac
     1261 gatagtattt ttaatctctg tttttctagc aggtgtttta tccttttttt ctccttgtat
     1321 ttttcctctt ctgccagtct atgctgggat tttattggat gatcaagaaa gggcaaaaag
     1381 cttttctttg tttgggagaa aggttctctg gtcaggcttg attcgaacac tttgctttat
     1441 cgctggtatc tctctcattt tctttattct aggctttggt gctggttact ttggtcatat
     1501 tctctatgca aattggtttc gatatgtcat gggagctatt attatcattt tgggtcttca
     1561 ccagatggaa atttttcatt tgaagaaatt agaagttcaa aaaagtttta cctttaaaaa
     1621 atcagattct aatcgttatt ggtcagcttt tttacttggt attaccttta gctttggttg
     1681 gacaccttgt attggtccag ttttaagttc tgttttagca cttgcggctt ctggaggcaa
     1741 tggtgcttgg caaggagcga tttatactct catttacact ctgggcatgg cccttccttt
     1801 cttggtcttg gcactagctt caggtctagt catgccatat tttagtaaaa tcaagcgtca
     1861 tatgatgcta ctaaagaaaa ttggtggttt cctcattgtt ttaatgggaa ttttgttact
     1921 attaggacaa gtaaatgttc tagctggaat ttttgaataa aggaggacaa atgaaaaaag
     1981 taatgtttgc tggcttaagt ctcttgtcat tagttgtatt gatggcctgt ggtgaggaag
     2041 aaactaaaaa gactcaagca gcacaacagc caaaacaaca aacgactgta caacaaattt
     2101 ctgttggaaa agatgttcca gactttacat tgcaatccat ggatggcaaa gaagttaagt
     2161 tatctgattt taagggtaaa aaggtttact tgaagttttg ggcttcatgg tgtggtccat
     2221 gcaagaaaag tatgccagag ttgatggaac tagcggcgaa accagatcgt gatttcgaaa
     2281 ttcttactgt cattgcacca ggaattcaag gtgaaaaaac tgttgagcaa ttcccacaat
     2341 ggttccaaga acaaggatat aaggatatcc cagttcttta tgataccaaa gcaaccacct
     2401 tccaagctta tcaaattcga agcattccta cagaatattt aattgatagc caaggaaaga
     2461 ttggaaagat tcaatttggt gctatcagta atgcggatgc agaagcagca tttaaagaaa
     2521 tgaactagaa tcgataaaat ctgattacaa gatgtagtca gattttggta acttctaaaa
     2581 ctaacttcca gtttcccaca acctagcttt tagtatgaga aaaacgcgtg acatcagtgg
     2641 aaatccgtct tagactaact tccactggtt ttctttttct tgatatataa gggttcaaaa
     2701 gcgaaaagac tcagaaaaag tgcacgacaa atagccctaa aacagagtcg tcttagagta
     2761 acttccagtt ttgggagaga gatggaagtt actttgagaa gttacggtag tcagattttt
     2821 ttagaaaaac attttataaa tattcacata tctcctatat ttatggtaaa atagaattat
     2881 cagtttattt tggagtcaaa gatgaatata tttagaacaa agaatgttag tttagataaa
     2941 acagagatgc ataggcattt gaagttatgg gatttgattt tgctgggtat cggagccatg
     3001 gtagggacag gcgtctttac aatcacaggt actgcagctg caacacttgc tggcccagcc
     3061 ctagtgattt caatcgttat ttctgccttg tgtgtgggat tatcagccct cttttttgca
     3121 gaatttgcct cgcgagtacc cgctacagga ggtgcctata gttacctcta tgctatctta
     3181 ggagaattcc ctgcctggtt ggctggttgg ttaaccatga tggagttcat gacagccata
     3241 tcaggcgtag cttcgggttg ggcagcttat tttaaaggct tgctctctca atacgggata
     3301 gcctttcctc aggctttaaa tggtaccttt aatcctcaag cagggacatt tgttgattta
     3361 ttgcctattc ttgtcttggt cttggtgact tcgcttgttt tactaaatgc caaggcagcc
     3421 ttacgcttta attcgattct agttattttg aaattttccg ctttagctct ctttgtttta
     3481 gtaggaattt ggaatattaa gtttgataat tggagcaatt ttgctcctta cggttttgga
     3541 caaatctatg gagctagtac tggtattatg gctggtgcat ccttgatgtt cttcggtttt
     3601 ttgggatttg aatccatctc tatggctgta gatgaagtca agactcctca aaaaaatatt
     3661 cctagaggga ttgtcttatc gctttctatc gtaaccattc tctatgcctt ggtgaccctt
     3721 gttttgactg gtgtggttca ctatagtcat ttaaatgtcg atgatgccgt tgcctttgcc
     3781 cttcgtagtg ttgggattag ttgggcagcc aactatgtgt cattagtggc tatcttgacc
     3841 ttgattacag tttgtatttc gatgacctat gccctatcgc gtatgattta cagtttagca
     3901 cgtgacggct tagtgcctgc tgcctttaag gaactgacga agactagcaa gataccaaag
     3961 aatgctacta tcttgacagg tctagcttca gcagtagcag caggaatgtt cccactagcc
     4021 agtattgcag cctttttaaa tatttgtacc ttagcctact tgatcatgtt ggcttatggt
     4081 ctgattcgct tacggaaaga aaaaggaatg cccaaagctg gggaatttaa aacaccattg
     4141 gtacctctgt taccaatttt atcgatcatc atttgtttat ccttcatgtt acagtataat
     4201 atgaatacct ggattgcttt cctagttgcg ttgttagtag gaagtattat ttacttcact
     4261 tatggctata agcattctac catagaagaa taaagtgaaa gtctattgag ttgttgacac
     4321 tcagcagatt tttatatgtg aaagaaattt caaatttttt ctaaaaatat cttgacagat
     4381 taaattttca ggagtagaat atttactagt taattaaatg gttaaggagt tgttcatgaa
     4441 gaaacaaaat ttatttttag tcctgttaag tgtctttctt ttgtgcttgg gggcttgtgg
     4501 tcaaaaggaa agtcagacag gaaaggggat gaaaattgtg accagttttt atcctatcta
     4561 cgctatggtt aaggaagtat ctggtgactt gaatgatgtt cggatgattc agtcaagtag
     4621 tggtattcac tcctttgaac cttcggcaaa tgatatcgca gccatctatg atgcagatgt
     4681 ctttgtttac cattctcata cactcgaatc ttgggcagga agtctggatc caaatctaaa
     4741 aaaatccaaa gtgaaggtct tagaggcttc tgagggaatg accttggaac gtgtccctgg
     4801 actagaggat gtggaagcag gggatggagt tgatgaaaaa acgctctatg accctcacac
     4861 atggctagat cctgaaaaag ctggagaaga agcccaaatt atcgctgata aactttcaga
     4921 ggtggatagt gagcataaag agacttatca aaaaaatgcg caagccttta tcaaaaaagc
     4981 tcaggaattg actaagaaat tccaaccaaa atttgaaaaa gcgactcaga aaacatttgt
     5041 aacacaacat acagcctttt cttatctagc gaagagattt gggcttaatc aacttggtat
     5101 tgcaggtatc tctcctgaac aagaaccaag tccacgacaa ctaacagaaa ttcaggaatt
     5161 tgttaagacc tataaggtta aaacgatttt tacagaaagt aacgcttctt caaaagtagc
     5221 tgaaactctt gtcaaatcaa caggtgtggg tcttaaaact ctgaatcctt tagagtcaga
     5281 cccacaaaat gacaagacct atttagaaaa tcttgaagaa aatatgagta ttctagcaga
     5341 agaattaaag tgaggaaaga atgaaaatca ataaaaaata tctagcaggt tcagtggcag
     5401 tccttgccct aagtgtttgt tcctatgaac ttggtcgtca ccaagctggt caggttaaga
     5461 aagagtctaa tcgagtttct tatatagatg gtgatcaggc tggtcaaaag gcagaaaatt
     5521 tgacaccaga tgaagtcagt aagagggagg ggatcaacgc cgaacaaatc gtcatcaaga
     5581 ttacggatca aggttatgtg acctctcatg gagaccatta tcattactat aatggcaagg
     5641 tcccttatga tgccatcatc agtgaagagc tcctcatgaa agatccgaat tatcagttga
     5701 aggattcaga cattgtcaat gaaatcaagg gtggttatgt cattaaggta aacggtaaat
     5761 actatgttta ccttaaggat gcagctcatg cggataatat tcggacaaaa gaagagatta
     5821 aacgtcagaa gcaggaacgc agtcataatc ataactcaag agcagataat gctgttgctg
     5881 cagccagagc ccaaggacgt tatacaacgg atgatgggta tatcttcaat gcatctgata
     5941 tcattgagga cacgggtgat gcttatatcg ttcctcacgg cgaccattac cattacattc
     6001 ctaagaatga gttatcagct agcgagttag ctgctgcaga agcctattgg aatgggaagc
     6061 agggatctcg tccttcttca agttctagtt ataatgcaaa tacagctcaa ccaagattgt
     6121 cagagaacca caatctgact gtcactccaa cttatcatca aaatcaaggg gaaaacattt
     6181 caagcctttt acgtgaattg tatgctaaac ccttatcaga acgccatgtg gaatctgatg
     6241 gccttatttt cgacccagcg caaatcacaa gtcgaaccgc cagaggtgta gctgtccctc
     6301 atggtaacca ttaccacttt atcccttatg aacaaatgtc tgaattggaa aaacgaattg
     6361 ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca agaccagaag
     6421 aaccaagtcc acaactgact ccagaaccta gtccaagtcc gcaacctgca ccaaatcctc
     6481 aaccagctcc aagcaatcca attgatgaga aattggtcaa agaagctgtt cgaaaagtag
     6541 gcgatggtta tgtctttgag gagaatggag tttctcgtta tatcccagcc aaggatcttt
     6601 cagcagaaac agcagcaggc attgatagca aactggccaa gcaggaaagt ttatctcata
     6661 agctaggaac taagaaaact gacctcccat ctagtgatcg agaattttac aataaggctt
     6721 atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga caagttgatt
     6781 ttgaggcttt ggataacctg ttggaacgac tcaaggatgt ctcaagtgat aaagtcaagt
     6841 tagtggaaga tattcttgcc ttcttagctc cgattcgtca tccagaacgt ttaggaaaac
     6901 caaatgcgca aattacctac actgatgatg agattcaagt agccaagttg gcaggcaagt
     6961 acacaacaga agacggttat atctttgatc ctcgtgatat aaccagtgat gagggggatg
     7021 cctatgtaac tccacatatg acccatagcc actggattaa aaaagatagt ttgtctgaag
     7081 ctgagagagc ggcagcccag gcttatgcta aagagaaagg tttgacccct ccttcgacag
     7141 accatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgtga
     7201 aagcagctaa gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag
     7261 tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc aaatttgagt
     7321 ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga
     7381 ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcagataat ggttttggta
     7441 acgctagcga ccatgttcgt aaaaataagg cagaccaaga cagtaaacct gatgaagata
     7501 aggaacatga tgaagtaagt gagccaactc accctgaatc tgatgaaaaa gagaatcacg
     7561 ctggtttaaa tccttcagca gataatcttt ataaaccaag cactgatacg gaagagacag
     7621 aggaagaagc tgaagatacc acagatgagg ctgaaattcc tcaagtagag cattctgt
//
LOCUS       DBEJNA010000061         6997 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEJNA010000061 DBEJNA010000000
VERSION     DBEJNA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.61"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..1505)
                     /gene="glpK"
                     /locus_tag="ACL3JB_001978"
     CDS             complement(<1..1505)
                     /gene="glpK"
                     /locus_tag="ACL3JB_001978"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0686638.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1664..3091)
                     /locus_tag="ACL3JB_001979"
     CDS             complement(1664..3091)
                     /locus_tag="ACL3JB_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0686639.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3256..4128
                     /gene="hslO"
                     /locus_tag="ACL3JB_001980"
     CDS             3256..4128
                     /gene="hslO"
                     /locus_tag="ACL3JB_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0686640.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4115..5095
                     /gene="dusB"
                     /locus_tag="ACL3JB_001981"
     CDS             4115..5095
                     /gene="dusB"
                     /locus_tag="ACL3JB_001981"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0686641.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            5191..6539
                     /locus_tag="ACL3JB_001982"
                     /pseudo
     CDS             5191..6539
                     /locus_tag="ACL3JB_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(6718..>6997)
                     /locus_tag="ACL3JB_001983"
     CDS             complement(6718..>6997)
                     /locus_tag="ACL3JB_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0686642.1"
                     /translation="PQPEGKKPSVPAQPGTEDKKLSAPKPDMQPSPQPEGKKPSVPEI
                     NQEKEKAKLAVATEKKLPSTGVASNLVLEIIGLLGLIGTSFIAMKRRK"
BASE COUNT         2147 a         1552 c         1361 g         1937 t
ORIGIN      
        1 tcatcgattt ccgcaaagac ttgagttgct ttcacagcct tcttccagcc cttgtagagt
       61 tgttccttgc gagattcgtt catagatggc tcaaagagtt ctcctgtctc gttcaagagt
      121 ttcaactcgt ccaagtcttt ccagtaccct actgacaaac ctgctaggaa ggccgctcct
      181 agagctgttg tttccaggtt tttagcacgt gcaatgtcaa tgcctaaaat atccgcctgg
      241 aactgcatga ggaagttgtt catggctgca ccaccatcca ccttcagtac ttgaatggcg
      301 gtctgagtat ccacttgcat ggtgtcgatg atatcacgca cttgataagc aatagattgc
      361 aaagtcgcct tgataaagtc ttctttgctt gttccacgag tcaaaccaaa gacggaacca
      421 cgagcatttt ggttccagta tggagcgcct agacctgtaa aggctggaac gacataaact
      481 tcatcgttgt tgtgagaatc acgagcgtat ttttcagatt ctggtgaatt ttcaaccatg
      541 cgaagaccgt cacgaagcca ctgaatagca cttcctgcga tgaagataga accttccaag
      601 gcataataaa ccttaccgtt gattccgtaa ccaatggttg tcaagaggtt gttttcagac
      661 aactgcatct cttccccagt attcatgatg atgaaagagc ctgttccata agtattctta
      721 accatacctg gctcaaaagc caactgtcca aagagggctg cttgttggtc cccagccata
      781 cctgagattg gcacctctcc accgtagaaa tggaatggag ctgtcttgcc gtagatttcg
      841 gagttagaac gaacttctgg aagtatagcc ttcggaatgt taaggatttc caaaatctca
      901 tcatcccatt tgagttcttt aatgttataa agcatggtac gagctgcatt tgagtagtca
      961 gtcacgtgag ccgcaccgtc agtcaatttc caaaccaacc aagtatcgat agtaccaaag
     1021 agcaattccc ctttttctgc tcgctcttga gcaccttcta catgatccaa aatccaacga
     1081 accttggtag cagagaagta agcatcaata atcaaaccag tcttttcatg gaatttttcc
     1141 acataacctt ggctttttag ttgctcagcc aaaggtgctg tctggcgtga ctgccaaacg
     1201 atagcattgt agataggaag tcctgttttc ttatcccaga caaccgttgt ttcacgttgg
     1261 ttggtaatcc cgattgcctc gatttgattt ggcttgacac cactttcgat gaaagcaccc
     1321 gcaataactg actgaacaga gttccaaatt tcattggcat tgtgctcaac ccaacctgcc
     1381 tgagggaaaa tctgggtaaa ctctttttga ctcgagctaa ccttttcccc ttttttgttg
     1441 aaaatgatgg cacgagaact tgtagttccc tggtcaatgg ccatgatgta tttttcttgt
     1501 gacatgtact gtcctcctga taaagatctt gaggtatttc ctctttgcac ttactagtat
     1561 acaaaataaa gcgctttctt gtttatcaac tttttttaat ttttaaaaaa atgtgaggag
     1621 attgtgtgaa tttcacaaaa aagacctgga ttaaccaagc cttttaagtg aataataact
     1681 gacgaatccc tgccaaatct tccatatcca agtcattttt taaataatag actggggtct
     1741 gttccttctt atgaatcggg ttattggtaa ccagcaaatc ataatgccga ctagggtcat
     1801 aagcttcaat ggtaataaaa cgattgtatt ccaaataccg tttcaaaatg gctgccatcc
     1861 ttgaaaaaac aagaaaacca gatgtcaaat ccagaccaat ccgcatatgc tggccaccgt
     1921 tttcagccat atattcgatt aactggagcc attcccagag aatcttctta tctaaatctg
     1981 tcccctgttg aaaagcaggt agagcatgaa aaatctcctc tgctgtctct ttaaaatcat
     2041 gttccatcag taaatatgga tgacgattct ctaactggta cttgtagcga tcctgtaaaa
     2101 tatagccctt atagagatag acttgagcac aaagctgact gagttcatag gtgacatggt
     2161 cctctgtata atcccccaat agttcctcct tcttcatttc ttgaatcaat tgcgtcagta
     2221 aatctgccaa ctgccctcca aaaccaagaa tatactccat agtatgaaga ggaagaatgc
     2281 gatgagatag gagaaaagag aagaatatca tcatctcacc atcctcaact cctagtggaa
     2341 tatgttgccc agcaaaaaag gacggaacct ttctcagcaa acgaaggtag aaaatattgt
     2401 caaaataccc tcgcattttc tcttctatga cttgaaactg acaagcattg acccgaagac
     2461 gttgttgact gatgtgagcc cagagaacca agtccaattt ctgccccaca gacaaacttg
     2521 caccgcagat ttcctctaaa ttggcaatct cctgttttct ctctggtttc tgcatgtgac
     2581 cttcccattc ctgactcgac cagacctttc ggaaaagaca gaaatagaaa tagcgaatct
     2641 gatgctctgg acctcgccaa cgtccatttt ggatggataa atcaaattct gacaaaatct
     2701 gatttaaacc agccaagtga cgaccaagcg tagcctcgct aatcaccaat tcttgagcca
     2761 gctgatgggc taaaaactgt tggtggtaga gaagataaac caaaatctgg tatttaacag
     2821 cactctccaa aaacaagctc cgaatatctc tccccttggt agctgcaccg atagacagac
     2881 gcagattttc atcttctgag tgaatagtca gttctaagcc actatccaaa gccttgtcat
     2941 tgagcagggt gacatatttg gttagggttg cttttgaaaa tcctgtttct tccattacag
     3001 ccttgacggt cgtctgagac tcttgtaata gaaaggaaag gattgaaaat tgaccacact
     3061 cggctttctc catcaaatct cctaaataca tttgttaccc ctttcatttt ctaccttaag
     3121 catagcataa atcttacaaa tgctaaaata atctgtttct ctttttattt tcatgctgat
     3181 ttcctggtcc attatcctga aaatcagtaa acacacggct ccccctttgg gcatttttat
     3241 gctaaaatag tagctatgga taaaattatt aaaactatat cagaaagcgg agcctttcgt
     3301 gcttttgtcc ttgacagcac ggaaaccgtc cgcactgctc aagaaaaaca ccaaacccaa
     3361 gctagctcaa ctgtagcgct tggtcgaact cttatcgcta gccagattct cgcagccaat
     3421 gaaaaaggaa ataccaaact tacagttaag gtgttgggat ctagctctct aggtgctatt
     3481 atcaccgtcg ctgataccaa ggggaacgtc aaaggctacg ttcaaaatcc tggtgttgac
     3541 atcaaaaaga ctgcgactgg tgaagtccta gtcggacctt ttgttggaaa tggtcaattc
     3601 ctcgttatca cagactacgg tactggaaat ccttacaact ctataactcc cctcatctct
     3661 ggagaaatcg gtgaagacct tgccttttac cttactgaaa gccaacaaac gccttcagcg
     3721 gtcggcctca atgtcctttt ggacgaggaa gacaaggtca aggttgcagg tggtttccta
     3781 gttcaagtct tgccaggagc caagaaagaa gagattgctc gctttgaaaa acgcatccaa
     3841 gaaatgccag ctatctctac tcttctcgaa agcgacgacc atatcgaagc cctcctcaag
     3901 gctatctacg gggacgaagc ctacaagcgt ctttctgaag aagaaatccg tttccaatgt
     3961 gactgtagcc atgaacgctt tatgaacgct cttgccagcc ttccaagctc agacttacag
     4021 gaaatgaaag aggaagacca cggggcagaa atcacttgtc aattctgcca aactacttac
     4081 aactttgatg aaaaggacct ggaggaactc attcgtgaca aatcttaata caccttttat
     4141 gattggcaat gttgagattc ccaatcgtac cgttttagcg cctatggctg gcgtgaccaa
     4201 ctcagccttt cgtaccatcg caaaagagct cggagctgga ctcgttgtaa tggaaatggt
     4261 ctctgacaag ggaatccaat acaacaacga aaaaaccctg cacatgcttc atatcgatga
     4321 gggcgaaaac cctgtctcta tccaactttt tggtagcgat gaagacagcc tagcacgcgc
     4381 agcagaattc atccaagaaa acaccaagac cgatatcgtc gatatcaaca tgggctgccc
     4441 tgtcaacaaa atcgtgaaga acgaagctgg tgctatgtgg ctcaaggatc ctgacaagat
     4501 ctactctatc atcaacaagg tccagtctgt ccttgatatc ccacttactg tcaaaatgcg
     4561 taccggctgg gcggacccat ctctggcagt agaaaatgct ctcgctgctg aggctgcagg
     4621 tgtttctgcc ctcgccatgc atggccgtac ccgtgaacaa atgtatactg gccacgcaga
     4681 ccttgagacc ctttacaagg ttgcccaagc tctaaccaag attccattca tcgccaacgg
     4741 tgatatccgt actgtccaag aagccaagca acgcatcgaa gaagttggtg ctgacgcagt
     4801 catgattggc cgagctgcca tgggaaatcc ttacctcttc aaccaaatca accattactt
     4861 tgaaacagga gaaatcctac ctgatttgac ctttgaagac aagatgaaga tcgcctacga
     4921 acacttgaaa cgattgatta acctcaaagg agaaaacgtc gcagttcgtg aattccgcgg
     4981 cctcgctcct cactatctcc gtggaacatc tggcgctgcc aaactccgtg gagccatttc
     5041 gcaagctagc accctagcag agattgaagc cctcttgcaa ttggagaagg catagtctta
     5101 catctacaac tcagaaaaac ggcaaagctc aaaatgaact accccaaaaa agttagacag
     5161 aaaaaatcta acttttgggg tgtttttatt atgaaactaa cttatgatga taaagttcag
     5221 atctatgaac ttagaaaaca aggatatagc ttagagaagc tttcaaataa atttgggata
     5281 aataattcta atattaggta catgattaaa ttgattgatc gttacggaat agagttcgtc
     5341 aaaaaaggaa aaaatcgtta ctattttcct gatttaaaac aagaaatgat taataaagtc
     5401 ttacatgaag gctgaactaa agatagagtt tctcttgaat acggcctccc aagtcgtacg
     5461 atacttctta attggctagc acaatacaag aaaaacgggt atactattgt tgagaaaaca
     5521 agagggagag tacctaaaat gggacgtaag ccacaaaaga gacctgaaga gaggacagaa
     5581 ttagaacgtc ttcaagcaga aaatgagtac ctgagagcgg agaatgctat cctaaaaaag
     5641 ttaagagaac tccgatggaa ggaggaaaaa gagaaagaag aaagacagaa attgttcaag
     5701 aattaatgac tgagttttcg ttagatattc ttctaaaagc cattaaacta gctcgttgga
     5761 cctactacta tcacttgaaa cagctagaca aaacagataa ggaccaagag cttaaagctg
     5821 aaattcaatc catttttatc gaacacaagg gaaattatgc ttatcgccgg gttcatttag
     5881 aactaagaaa tcgtgcttat ctggtaaatc ataaaagagt tcaaggcttg ataaaagtac
     5941 tcaatttaca agctaaaatg cgacagaaac gaaaatattc ttctcataaa ggagacgttg
     6001 gcaagaaggc agagaatctc attcaaggcc aatttgaagg ctctaaaaca atggaaaagt
     6061 gctacacaga tgtgacagaa tttgccattc cagcaagtac tcaaaagctt tacttatcac
     6121 cagttttaga tggctttaac agcgaaatta tcgcctataa tctttcaact tcacccaatt
     6181 tagaacaagt acaaacaatg ttggaacagt cattcacaga gaagcactac gagaatacga
     6241 ttctccatag tgaccaaggc tggcaatatc aacacgattc ttatcatcag tttcttgagg
     6301 gtaagggaat tcaagcatcc atttcacgta agggtaacag cccagacaat ggtatgatgg
     6361 agtccttttt tgggattctg aaatcggaaa tgttttatgg ctatgagaaa acatttaaat
     6421 cacttaatcg attggaacaa gctattgtag actatattga ttactacaac aataaacgaa
     6481 ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc ttcggataaa
     6541 ttaattgtct aacttttgcg gttcactagc cttctctttt tatatcttag attcatctct
     6601 atatgaaatg acttataatt attagatacc aattataagt aaaatctttg ggatcttcaa
     6661 tggttaacca atcaaatgct aaatatcgaa agtggatatt tttaaaaaac tgaatcatta
     6721 ttttcttctt ttcatcgcga tgaatgaagt tccaatcaaa ccaaggagac caatgatctc
     6781 aagaactaga ttagacgcca ctcctgtaga tggcaatttc ttctctgttg ctacagcaag
     6841 cttagctttt tctttctcct gattaatctc tggtacactt ggtttcttac cctctggttg
     6901 agggcttggt tgcatatctg gttttggagc agatagcttt ttatcctcag taccgggttg
     6961 tgccggtaca cttggtttct tgccttctgg ttgagga
//
LOCUS       DBEJNA010000062         6826 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEJNA010000062 DBEJNA010000000
VERSION     DBEJNA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.62"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..339)
                     /locus_tag="ACL3JB_001984"
                     /pseudo
     CDS             complement(1..339)
                     /locus_tag="ACL3JB_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            537..2303
                     /gene="patB"
                     /locus_tag="ACL3JB_001985"
     CDS             537..2303
                     /gene="patB"
                     /locus_tag="ACL3JB_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0686643.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMIDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2442..3131
                     /locus_tag="ACL3JB_001986"
     CDS             2442..3131
                     /locus_tag="ACL3JB_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0686644.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3135..3314
                     /locus_tag="ACL3JB_001987"
     CDS             3135..3314
                     /locus_tag="ACL3JB_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686645.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNYDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3301..4650
                     /locus_tag="ACL3JB_001988"
     CDS             3301..4650
                     /locus_tag="ACL3JB_001988"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0686646.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4774..6234
                     /gene="gltX"
                     /locus_tag="ACL3JB_001989"
     CDS             4774..6234
                     /gene="gltX"
                     /locus_tag="ACL3JB_001989"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0686647.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGEHSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6248..6682
                     /locus_tag="ACL3JB_001990"
     CDS             6248..6682
                     /locus_tag="ACL3JB_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0686648.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2152 a         1302 c         1473 g         1899 t
ORIGIN      
        1 ttctaactta gtcttaagat aggccttaaa agcaggtgaa aagcgagggc atgctttggc
       61 agcttgtatg agtgcctacc gcagatgagg ggaaccccgt ttgatcattc ttccagctaa
      121 atcaatctga tctgactgat aaatagaaga atccagtcca gcgaaagctt gtaattgagc
      181 aagattatca aaggcatgaa tatttcgaat ctcggctaaa atgaccgccc ctaaacgatt
      241 cccaatccca gtaaccgtcg tgatgatcga gttgaactca gccatcaagt cattgacaca
      301 tgtttccgcc ttgtcaatga gcctcttgta atgtttgatg ttttcattac acgagataaa
      361 acgtttatgc gttatcaaac tcatgaccaa ttgaaacaaa aagctgtggt tagatccttt
      421 cggaaattgt caagcgattg gaggaaatga actaatccac agcggcttat tccaagtata
      481 ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg agtaaaatga
      541 agacagttca atttttttgg cattatttta aggtctacaa gttctcattt gtagttgtca
      601 tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt tctggacaag
      661 cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca gaacttgtat
      721 ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt ctatttatct
      781 ctagtgtaat atacatgtgt ctcatgacgc gcgtgattgc agaatcgacc aacgagatgc
      841 gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac cgtcgacaag
      901 atggcgatat cctgtctcat tttaccagtg atttggataa tatcctccaa gcctttaacg
      961 aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt cttgtcatgt
     1021 tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg gctttcctta
     1081 tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag aaagaggtag
     1141 ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg attgtgcaag
     1201 gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg cgcaaggcaa
     1261 cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg atgagcctga
     1321 ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat aagtctattg
     1381 aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag cagtactacc
     1441 agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt actggagctg
     1501 aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag gctccaacct
     1561 tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac ttgcctgata
     1621 aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca gcagttgttg
     1681 ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt tatgatgttg
     1741 atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta gatagtctta
     1801 gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg attagagaca
     1861 atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca gcaaaagcaa
     1921 cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt attgatgatg
     1981 accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga accctgatga
     2041 tagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg gtgacagaaa
     2101 gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc gtcattgccc
     2161 accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat ggagaagtca
     2221 ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca gaactctatc
     2281 acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct ttttcttgtc
     2341 cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc attttgagtg
     2401 atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga acggttgtag
     2461 gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat tcatctgtat
     2521 cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc attcctgttg
     2581 gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt ttgacaggag
     2641 gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc gatgattaca
     2701 atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt cagaataaac
     2761 caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt ggaaccctca
     2821 atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac tctattgaga
     2881 cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc aactcagtcc
     2941 atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt gattcaagag
     3001 accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt ttacagtggc
     3061 atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag tatttattga
     3121 atgaactgta acgattggaa catctggtcg ttctttcttt tattttttca aaatttttag
     3181 aatgtggcat tttacgcaaa cgtttgaatt atgataaaaa ttggagaaat tcgacaaaaa
     3241 aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg gaggaagaac
     3301 atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc accacatgaa
     3361 gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa aggaactggt
     3421 gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgatcg cgaagaattt
     3481 gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt ggttgtgatc
     3541 ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa tcaccatttt
     3601 gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc aggaaactca
     3661 atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga cttctcagta
     3721 aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg tgtctttaaa
     3781 gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta tgcaacaact
     3841 gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg aacatttgtt
     3901 gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt gcttccaatc
     3961 gcagcatcag gagctgacat caaagctctt atggaaggtg cgaatgcagc tcgcaaagac
     4021 tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt tcgtaacatc
     4081 ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc acttcaatac
     4141 ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca aaaaggtatc
     4201 tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt tatccaagaa
     4261 ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa aaacgtgctt
     4321 attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa agacgttgac
     4381 tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg tgatgtacca
     4441 aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac tatctacttc
     4501 ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt tgaccaacca
     4561 ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg atttgaagaa
     4621 ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg cccactcttt
     4681 ttactctctt tatccataga aattggactc agccaagact tgtgatataa tatagaaagc
     4741 aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg cgtacgttac
     4801 gcaccaagtc caacaggact actacacatc ggaaatgctc gtacagcatt gtttaattac
     4861 ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac tgaccgtaaa
     4921 cgccatgtcg aggatggtga acattcacaa cttgaaaacc ttcgctggtt aggcatggat
     4981 tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt ggacttgtat
     5041 caaaaataca ttgaccaact attagctgaa ggaaaagcct ataaatctta cgttacagaa
     5101 gaagagttgg cagctgaacg cgaacgccaa gaagtagctg gcgaaacacc acgctacatc
     5161 aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga acgtgaagca
     5221 gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta caagtggcat
     5281 gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga ctggattatc
     5341 caaaagaaag acggttaccc aacttacaac tttgccgttg ttatcgatga ccacgatatg
     5401 caaatctctc atgttatccg tggagatgac catattgcta atacaccaaa acagcttatg
     5461 gtctatgaag ctcttggttg ggaagctcca gagttcggtc acatgacctt gattatcaac
     5521 tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt tatcgaagat
     5581 taccgaaaga aaggttacct tccagaagca gtctttaatt ttattgctct tcttggttgg
     5641 aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact ttttgatgaa
     5701 aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg gatgagcaat
     5761 gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc attcttagag
     5821 gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa accacaaatg
     5881 aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt cccagaattg
     5941 acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct tgaagcattc
     6001 aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat cttcccacaa
     6061 attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat gcctattcgt
     6121 atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt cttgcttgga
     6181 cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa ataaagagga
     6241 tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat acaatccaca
     6301 tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag cagaagatgg
     6361 acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc tctgcgcaga
     6421 acgggcggcc ctcttcaata tgtaccaatt ttcaggacaa actaaggtta agaaagtatt
     6481 agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg gtgcttgtag
     6541 agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga tggactataa
     6601 tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag aagaacgtgc
     6661 ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt actataagtt
     6721 gaaaaaataa aaaaaaatta gaaaaagtag ttgacaaagt ttgaaaagac tgtataatag
     6781 taagagttga aaataacaac tcaggtccgt tggtcaaggg gttaag
//
LOCUS       DBEJNA010000063         6805 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEJNA010000063 DBEJNA010000000
VERSION     DBEJNA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.63"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..325
                     /locus_tag="ACL3JB_001991"
     CDS             <1..325
                     /locus_tag="ACL3JB_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686649.1"
                     /translation="TNGELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDNAR
                     FHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAFLS
                     CSCFN"
     gene            386..1348
                     /locus_tag="ACL3JB_001992"
     CDS             386..1348
                     /locus_tag="ACL3JB_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0686650.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1525..2532
                     /gene="gap"
                     /locus_tag="ACL3JB_001993"
     CDS             1525..2532
                     /gene="gap"
                     /locus_tag="ACL3JB_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0686651.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2600..3475)
                     /locus_tag="ACL3JB_001994"
     CDS             complement(2600..3475)
                     /locus_tag="ACL3JB_001994"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0686652.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINKKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3562..5757
                     /gene="pbp2a"
                     /locus_tag="ACL3JB_001995"
     CDS             3562..5757
                     /gene="pbp2a"
                     /locus_tag="ACL3JB_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0686653.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTSAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYTVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5810..5962
                     /gene="rpmG"
                     /locus_tag="ACL3JB_001996"
     CDS             5810..5962
                     /gene="rpmG"
                     /locus_tag="ACL3JB_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0686654.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5972..6148
                     /gene="secE"
                     /locus_tag="ACL3JB_001997"
     CDS             5972..6148
                     /gene="secE"
                     /locus_tag="ACL3JB_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0686655.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6203..6739
                     /gene="nusG"
                     /locus_tag="ACL3JB_001998"
     CDS             6203..6739
                     /gene="nusG"
                     /locus_tag="ACL3JB_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0686656.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2118 a         1191 c         1471 g         2025 t
ORIGIN      
        1 aacaaatggt gagttaatcg ctccaatgac ttacgaagag acgatgacga gcgacttttt
       61 tgaagtatgg tttcagaagt ttttcttacc aacattaacc acaccatcgg ttattattat
      121 ggataatgca agattccata gaatggggaa gctagaactc ttgtgtgaag agtttgggca
      181 taaactttta cctcttcctc cctactcacc tgagtacaat cctattgaga aaacatgggc
      241 tcatatcaaa aagcacctca aaaaggtatt accaagttgc aatacctttt acgaggcttt
      301 tttatcctgc tcttgtttca attgactata tatcacggat acagttggga aagaagctat
      361 taaatatttg gagagtcctt ttgggatgaa catgtcaaat attactatag atgggcaaga
      421 aatggatctg agtcaaacga tgccttctta tgctcaagta gtgagtcttt atgatgatac
      481 aagtatctct gttagtaata atgagacgga caaagtgttg gctggatccc tctatactga
      541 tacaaatgaa cagggattaa cgattccaag cagtttacta aaaaattgga atgaacagac
      601 aggaaaaaat ttgacagcta atgatcttat tggcaaatca gtctcagcca gcattgtaga
      661 aagtgctgcc gaaactagta agattgctca atttcaaacg aagattgtac gtgtaatcaa
      721 tgatgaagat gacatggagg acagcaacag tttcatgctg tctcatcaaa tggaaacgat
      781 tttgaaagag gctggattta cgaaagctgt atcttatttt atcttggaac tcaaagatcc
      841 atcacagaca aaagtagtaa cagaagaatt acagaaaaat aagaagtata ctgtgctttc
      901 tcaacagaga gttcttgata ttgtgattac ctttattcgt gttattcagg gattattgat
      961 tgtgctttca tcacaagcta ttgtggtagc agcggttatg attggtatca ttatttacat
     1021 caatatcatg caacgttcca aggaaatagg tgtcatgaaa gcagttggtt atcagaatcg
     1081 tgatgtcaaa ggaattttta tttacgaggc tatctggatt gtaggcatcg ccttgctgct
     1141 ggcatttttg gttgcacaag gggtgggaag tttggcgaat gcgattgtaa gtcactttta
     1201 cccatccatc actaaggttt ttgaattaaa tcttttatct gttttaggaa ctctagtttt
     1261 cgctctatta cttggttatg tctcagccta cttcccggcg cgtaagatta gtaaaatgga
     1321 tcctatagaa tcgttatgct atgaatagta agggattcct tggtttacag tcttaaaaag
     1381 aaactaacat agaaaaacaa tggccatact tgcaattcaa ctcaaatagt tgtataatag
     1441 gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa aaatttcatg
     1501 attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg tttcggacgt
     1561 atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt tacacgcatc
     1621 aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac aactcaaggt
     1681 cgtttcgacg gtactgttga agttaaagaa ggtggatttg aagttaacgg taaattcatc
     1741 aaagtttctg ctgaacgtga tccagaacaa atcgactggg ctactgacgg tgtagaaatc
     1801 gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca ccttaaaggt
     1861 ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac agttgtattc
     1921 aacactaacc acgacgttct tgacggtact gaaacagtta tctcaggtgc ttcatgtact
     1981 acaaactgct tggctccaat ggctaaagct cttcaagaca actttggtgt tgttgaagga
     2041 ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg accacaccgt
     2101 ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa ctcaactggt
     2161 gctgcaaaag ctatcggtct tgtaatccca gaattgaatg gtaaacttga tggatctgca
     2221 caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct tgaaaagaac
     2281 gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc atacggttac
     2341 acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc attgtttgac
     2401 gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt tgtatcatgg
     2461 tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata cttcgcaaag
     2521 attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc ttttttatat
     2581 ggaaaaatgg atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa
     2641 gggtagtgaa agttagcctc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat
     2701 gaagcataag ccggcttgtc tttgatttac tattatagag agggtctccc aggataggaa
     2761 gattatgatg caaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaat
     2821 gagccaagga agtcttgttt gagaattgct ttaatctgct tacatgcgtt tcagcatatt
     2881 gcccattttt tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt
     2941 ctctgaaaac aagttctttt ttgttgatat ttccatcaac tagagcccaa tattctctag
     3001 aaatctcttt tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa
     3061 agagaactaa gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa
     3121 cataggtact aacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca
     3181 taccctctgg tttgtttaca ataatcaagt gttgatcttg ataaacttcc tgcactaagt
     3241 ctgggttgcc ccaagggatc gtcttttggg gataatcttc ctcgtcaaaa gtcaactggc
     3301 aaacatctcc aggatttacg atttcgttcc agtggacttc ttcttgattt atcaaaatat
     3361 gtttcttgat tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta
     3421 attgctttac cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga
     3481 tattgtaaca aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga
     3541 tgaagatgat aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt
     3601 tttaaaaaag aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt
     3661 agtgatcgaa aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat
     3721 ctaacaaaga ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg
     3781 tttgctgtag ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa aactcggact
     3841 cttatttttg atcgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat
     3901 gttgagctga ctgatatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt
     3961 tctttctata aaaatgacgg gattaactat ggccgtttct tcttggctat tgtcactgct
     4021 ggacgttcag gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatca
     4081 caagatcaaa ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa
     4141 aaatatagta aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt
     4201 gtgtggggtg tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt
     4261 ctggatcaag ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg
     4321 aattccgtag aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca
     4381 ggatatattg ataaaaacca agaaaccgaa gctgctgaag ttgatatgac ttcgcaattg
     4441 cacgataagt atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg
     4501 gttaatgaag ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac
     4561 cgcatttaca cagagctgga ccaaaactac caagcaaata tgcagattgt ttatgaaaac
     4621 acatcgctat ttccgagggc agaggatgga acgtctgctc aatcaggaag tgtagctctc
     4681 gaaccgaaaa cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact
     4741 ggattccgga atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag
     4801 cctttagttg tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat
     4861 aaccatacca tgcagtatga cagctatacg gttgataact atgcagggat caaaacgagt
     4921 cgagaagttc ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccact
     4981 gttaatgatt tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg actcaacatg
     5041 gaaaaggtcg accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt
     5101 caaatggctc aagcatacgc tgcctttgca aatgaaggtt taatgcctga agctcatttt
     5161 attagtagaa ttgaaaatgc tagtggacaa gttattgcga atcataaaaa ttcacaaaaa
     5221 cgggtgattg ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc
     5281 aacggtaccg gtattagttc atcgcctgca gactatgtca tggcagggaa aactggaaca
     5341 actgaagcag ttttcaatcc ggagtacaca agtgaccagt gggtaattgg ttatactccg
     5401 gatgtagtga ttagccactg gcttggcttt ccgaccactg atgaaaatca ctatctagct
     5461 ggctctactt caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct
     5521 tatacgccag gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca
     5581 gccaatacaa aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct
     5641 gatattcgag ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg
     5701 aagattaagg aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat
     5761 gcttgtcaaa gcctagcttt cttgttataa tggataagat ggaggcgtta tggcactaaa
     5821 aaaagcaagc ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca agatcagcgg
     5881 aaaccccaag cctacacgac tagaagtaaa taaattttgt aagcattgtg gcaagtacac
     5941 tacacacaga gaaacgagat aggagagagc gatgcgtttt attggagata tttttagact
     6001 tcttaaagac acaacatggc caactcgcaa ggaaagctgg agagattttc gttctatcat
     6061 ggaatacaca gctttctttg tagtaattat ttacattttt gaccagttga ttgtttcagg
     6121 tttgattcga tttattaaca ttttttagaa gattagtgga gttaattaca ctagaaatct
     6181 tctatttatg aaaggaaata tcatggatag ttttgataaa ggatggtttg ttttacaaac
     6241 ttattctggt tatgaaaata aggtgaaaga aaatctatta caacgtgcac aaacctacaa
     6301 tatgttggat aatattctac gcgttgaaat tccaacacaa acagtgcaag ttgaaaaaaa
     6361 tggaaagaga aaagaagtag aagaaaatcg ctttccaggt tatgttcttg tagaaatggt
     6421 catgacagat gaagcttggt ttgttgttcg aaacacacca aatgttacag gatttgtcgg
     6481 atcacacggg aacagatcaa aaccaactcc attattggaa caagaaattc gtgacatttt
     6541 ggtatctatg ggacaaactg ttcaagaatt tgatttcgat gttgagattg gtcaaactgt
     6601 acgtattatt gatggtgctt ttgcagacta cactggtaag attacagaaa ttgataataa
     6661 caaagtgaaa atgattatct ctatgtttgg taatgacaca gttgcagaag taaacctaaa
     6721 ccaaatcgca gaattataat cctgagagag gctggagcct ctcttttttg tgcagtttag
     6781 gagctaaagg gaacagaatg gagaa
//
LOCUS       DBEJNA010000064         5899 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEJNA010000064 DBEJNA010000000
VERSION     DBEJNA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.64"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(98..1324)
                     /locus_tag="ACL3JB_001999"
     CDS             complement(98..1324)
                     /locus_tag="ACL3JB_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0686657.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1396..2061)
                     /locus_tag="ACL3JB_002000"
     CDS             complement(1396..2061)
                     /locus_tag="ACL3JB_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0686658.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2129..2326)
                     /locus_tag="ACL3JB_002001"
     CDS             complement(2129..2326)
                     /locus_tag="ACL3JB_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGR0686659.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2617..3480)
                     /locus_tag="ACL3JB_002002"
     CDS             complement(2617..3480)
                     /locus_tag="ACL3JB_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0686660.1"
                     /translation="MIERMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            complement(3875..5046)
                     /locus_tag="ACL3JB_002003"
                     /pseudo
     CDS             complement(3875..5046)
                     /locus_tag="ACL3JB_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(5059..5808)
                     /locus_tag="ACL3JB_002004"
     CDS             complement(5059..5808)
                     /locus_tag="ACL3JB_002004"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0686661.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
BASE COUNT         2050 a         1117 c          912 g         1820 t
ORIGIN      
        1 tataacacat tcagaaaaga gaaaaaagtc tgttgatttt gaccatcata aaaagactgg
       61 caatccagtc tcaaacatat attatagaaa ttctccacta aatactttca cgaatattca
      121 gaagcataac aaaggcaact agaagaaata gcaataaaac aaagctaact gccagagttc
      181 caaagctagt agcaatggtt accaaagcta ttgtaaataa gctaggtaaa acaaccgtaa
      241 tggcaccgat agaggattga actgctccca ttgactcctc aggtatttgt ttaaaaacga
      301 gttcttgcaa tctaggagag agaacacctg cgaaaaaggc atccaaggta ctaaagatga
      361 gaatccagtc aaaacgaact gtggcaaatc ctactagaag aagcaactgg atgacaagtg
      421 aggcatagag agctgttttt atggaaatgg tatgttgcag atagccactt acaaggcttc
      481 cgacaatcag ggctgacagt tcaaaagtgg atagcaaggc aagagattga cctgtttgta
      541 aattcaaaaa gggttgattc ctcaaaaata gagtagagac aggaactgta acatttatca
      601 ctgcttgact agtagagata ataaacaaaa ccaagagcac cttattcata ttccatatca
      661 atttcgatga ttggagcaaa tgctggcaaa aggattttac agagagtcct tcttgatagt
      721 taatcgtttt ttctactttc aagaggtcag tttttatgaa gaggatacct aaaaatgcga
      781 ttaaaaaggt aagagcgttc agcaaggaaa tgaactggat ggagagaatc cctagcaaga
      841 ctcctcctag aatattactg attgttttca ctaaactaac agttgactgt ttaaatccaa
      901 tagcttctgc cagatggtct tgcccaataa ttctaatgaa aatcggagtg agcatggctc
      961 ctgaaaagta actcaatgtg tcagacaaga ggttaagcag acaaataaat gctactagca
     1021 acaaggagaa agactgccct gaaagtgata aagaaacgat agagtaaagc aaaaattttg
     1081 caaaactaat gactgtgtat ttcaagacac gatgatgttg aaaatctgcc aaaactccca
     1141 gaaagatttg taaaatttgg ggaagggttt ctgaaatcgt aatgagtaaa atcgccaaag
     1201 gtgcaaaaga cgcatctgcc acataattca gaaaggccag ataaaaaatc gtatccccaa
     1261 gcgttgaaat ccactggttg atagttaatt gcctaaaatc tctattttga agaaatactt
     1321 tcatcacaac tccttcttaa gttcaaatgg gaatctttcc ccaaggatag accgcgatac
     1381 tactaacaac caaaattaca gtaacatcaa aagctgacca atgccattgt agactatatg
     1441 cagtccaata ggccaataaa ttgactttgt cattctaaat aagactgcaa atataagacc
     1501 tccacccata tagaagacaa agtctgtcaa gacccaaccg tgattactaa tgtgcgagac
     1561 cccaaataaa acagcggaac caagtacatc tagcccccat ttctttcctt tttccagagc
     1621 agtcatcact aatccacgat aaatcatgtc ttcaaaaatg ggacctgcaa tcacaggata
     1681 aaaaaaatac atcaaaaatg ccgtagctcc tgtaaaagta ggagcagcat gttgataaga
     1741 aatttcattt cgagtaggtg ggaaaagaaa aaaggtgaca aaattccaag caacaaaagc
     1801 aagcagagct aggaaggaat agaaaagata ggatccttta aactttctac tattgatttt
     1861 ctgccatttc cccgaccaaa tcatagcaat aagagcaaat aaaaccacaa gaaaattcaa
     1921 catcatatcc gacagataat aggcaaagtc agatagccca gcaacaaggt cgctgcgtaa
     1981 aactaaaaca ctgaacttct ggtcagcaat aactagtaga aaaactataa taaagtagcg
     2041 gtgtgagatt atctttttca ttctattttc tcctatacta tgaaataaag acagtcccta
     2101 cccaagaaaa aggcaaggac tctgaatatc aataatggcg acgattaaca gtggaagaat
     2161 catggttaaa atatttcttc cagaaattag tgattgacca agacgttcct aaacctcccc
     2221 aagcaccggc tgggataaca gcattattcc caaattcccc tccataaact gtctccaact
     2281 cagcttctgt caattccatt gtttctgcaa attgtaaatt taacatcttt tacactcctt
     2341 caattatctt catttgtaaa ccacttctgc gacctaggat ttgcttcaag tgctttacaa
     2401 gtacagtata acacgaaaat tggcttattt taaaaaatcg catatttgat attttttctt
     2461 atagaaattt cttatttgcg attttgatag atttgattat ttccctggta taataaagtt
     2521 attactaaca aggaggaata taatagatga agaaaagaaa aatccaactg atactcctac
     2581 ttatttcgga gtgggttatt gtcattccat ttttaactaa tctataagtt ctttatattg
     2641 ctgaaaacgc aattcaaaaa gggatgttaa ttgtggattt tctaatacct gcagagattg
     2701 aataaagcgt tcaatctctt tttgattgct tccctttgtt tgaagaaaga cactcatctt
     2761 ctttaaaaat tgccacgata ctttttcaaa aacatcatac ggtcgtaaca tcctctccaa
     2821 ctcggcttcg aagattggga tgtaggagaa aagttttcgc tccatgagtt ctgataagat
     2881 atttaagagt ccttgcttca tatacaatcg attgtgtact aactctttaa attctttgga
     2941 tttttcgagt aaggaggttg ataaaaaaat cagatcttga ttgctcaaga agggcatggt
     3001 attgcaaaag agatagagtt caaaccaggt ccaagactcg atagcataga gataggtggt
     3061 caaaaactcg ctatcctcct ctgctagtgg gtagctttta tttagtgaat ggatggcatc
     3121 tttaatcacg atggcattca aacgacgata ggtctgcgcc atctgttctt gatcgacttc
     3181 ctccaatagc tgctctaaag cagctatatc ctgatgggca aagcgattca caacctttcg
     3241 accgattcgc atatgtggag attcttgata gttgttgagc ttgtgcccaa actcatcaaa
     3301 ggtcacattt ataccttgga tagctagaat caacttatcc gcagacagca tagactgccc
     3361 tagttcaaac ttggacaact gagaagctgt tagaccctca caagccacat ctgtctgctt
     3421 aagctttctc gccaaacgta attccttgta aaattccccc agttccattc tctcaatcat
     3481 ctgaccacct cctagctttt gcatattata tcattattta caatcatttg tcaaaatatt
     3541 ctgatattta agagggcaaa aaagccagcc ttaagctgac tctaaaagga ccgagccttg
     3601 tacaatacag aactcaatcc tcgttctaaa tagaatgtct aacttttttg ggcagtacac
     3661 gagcttgggg aacagccact ggaacgatga ggtgtgagct caaaatatcc tccagttatg
     3721 tttttcctaa tagtataccg gaagagtgaa aggattttat aatggagcgg ttacaaagaa
     3781 cctactttct attaaacagt atactatgaa aatgtgaaaa tttaacattt ttttgtacaa
     3841 attttataaa ttattgcctt tttaatatca atagttaatc tcttatccag atcccccttg
     3901 tgtaaacttt atctttataa gcttcaaggc ccctatccca tctatttgca acaattagat
     3961 cactttgttt tgtaaatagt tcaaaattct tttcaataat tacgttatct atactaacgt
     4021 ttaaatttgg ttcatatact aaaattttta taccgacaat caatagttca ttaattatac
     4081 ttaaaatagc tgactctttg taattatctg aattatattt catccccaat ttatatattc
     4141 ctactatctt tggctttcgt tccaatattt gtttaactat gaactgtttt ctatttgtgt
     4201 ttgaaatatc aatcgcttct atcactgggg catttatttc tataaattct ttttttaatt
     4261 gtttagtatc tttgggaaga caatatcctc caaatccaaa agaaggatta ttataaaaat
     4321 ttccaattct tggatctaaa caaacacctt ttattacaac ttcagcattt aagcttctcc
     4381 tctcagcaaa agaatctagt tcattaaaaa agcaacacgg agagctaaga atgtgttaga
     4441 aaaaagctta attgcttctg cttcagtagg agaaactaac ataacatttt taatattggc
     4501 agtactatga gtactaatcg aaaggaacaa ctctgcaatt tttcttcctt caactgtctc
     4561 atctccaaca actatgcgac ttggatataa attatcatat atagaacaac cttctctcaa
     4621 aaattcaggg acaaaaatga tattttttgt atcaaacagc ctttttaatt tgtttgaaaa
     4681 gccgatcgga actgttgact ttaaaataat ctttccatta ggttttaccc tcagaatctt
     4741 cgataccgtt tgttcgattt catatgtatt aaaactacca attttctcat cataatctgt
     4801 cggaagcgca ataatataat aatcaatatt atttttaatt tcagaaaatg tatcaaaaaa
     4861 agtaatattt aagttattct cgcaaaaaaa cttcataagc tcttcatttt tagatggaag
     4921 aatgcccttt tttaaattat ttatttttac agaatctata tcatatgcaa caactttata
     4981 tttagatgca aatagtaacg cgtaggccag cccaacatgc cccaaaccaa ttactgctat
     5041 attcataaaa ctacttcctt atttcttaat ccaaaatata atagaataag ctgccccatt
     5101 ccttaaatac aactctttaa tattgtttaa aagtttttca actgatttcc agattatcaa
     5161 aatctgagat ttatagcaca atattgatga tattctatca atataatgtt tttcatcgag
     5221 ttcctcttga tacattttta attctttagt ttttcccata taactaacca tactactatc
     5281 acttacatat gggaaatcct cataatatat tactttataa cgcataaatt caagcgccct
     5341 tccaatacta ttcacaaaaa catgatcaac atggtcacca agtgaaagcg gacaatatac
     5401 gacacatttg tcgtctaaat gcattaacag ctcttttatg atatcattct ttaatgtgtc
     5461 ctcatttttt aattcactat agatatgacg gtatagaaaa ttgccatttc tatctttcct
     5521 atagagacat tcatagtacg ataagtgtct aaaatcacat tgtagacgtt cacaagctaa
     5581 cctatcttct ttcttccttt cttcaatcgg atatttccca aggttacaca acttatgaaa
     5641 ttgcttagca gagggctgta gctgttgact caaagggtaa ccagaaaata tagtaataac
     5701 aagtacaatt tctccttctg aagttaattt tgaaatataa tcaccacagg aaaaaattgc
     5761 gtcatctaaa tgtggagata aaaagatata cttagtattg ttactcataa ccattccctc
     5821 tacaatttat ctaaaaactc actaagtgtc tgattaaatt ccacatcatc aaaaaaattc
     5881 accttattct taataatga
//
LOCUS       DBEJNA010000065         5412 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEJNA010000065 DBEJNA010000000
VERSION     DBEJNA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.65"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..110
                     /locus_tag="ACL3JB_002005"
     CDS             <1..110
                     /locus_tag="ACL3JB_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0686662.1"
                     /translation="KLIQKGFSLLELTEETSMLSHLKKEVEIYYQAKER"
     gene            complement(426..818)
                     /locus_tag="ACL3JB_002006"
                     /pseudo
     CDS             complement(426..818)
                     /locus_tag="ACL3JB_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase domain-containing
                     protein"
     gene            complement(835..1641)
                     /locus_tag="ACL3JB_002007"
     CDS             complement(835..1641)
                     /locus_tag="ACL3JB_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0686663.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1847..2488)
                     /locus_tag="ACL3JB_002008"
     CDS             complement(1847..2488)
                     /locus_tag="ACL3JB_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0686664.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(2485..4593)
                     /locus_tag="ACL3JB_002009"
     CDS             complement(2485..4593)
                     /locus_tag="ACL3JB_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0686665.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(4645..4896)
                     /locus_tag="ACL3JB_002010"
     CDS             complement(4645..4896)
                     /locus_tag="ACL3JB_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0686666.1"
                     /translation="MVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHT
                     ATVKDGNKFSKDRAEAEAWARASLTKIPPTGMEYFYGFE"
     gene            5323..5412
                     /locus_tag="ACL3JB_002011"
                     /pseudo
     CDS             5323..5412
                     /locus_tag="ACL3JB_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT         1687 a         1196 c          863 g         1666 t
ORIGIN      
        1 cgaaacttat ccaaaaaggg ttctcactcc tagagctgac cgaggaaact tctatgctgt
       61 ctcatctcaa aaaagaagta gagatctatt accaagcgaa ggaaagataa aaaagccgag
      121 ggatttcctc gactctttac atattatttg ttcgttagtt cttaatacca gccattgtta
      181 aaccagaagt ttttagctct gccaagccac atagtgtgtt tactactatg tggccatgtc
      241 accatgaatc gccgaacaat ttaacgagaa agtatgactt ttacgtttat cccaactcaa
      301 ttatgacatt tttttcaaaa gtcaatatat ctcacttttt caacgacaag aaagaggctg
      361 ccaattgacc accctcttat tctgaaccca tcactccatc actttttagc ttcattcgct
      421 ttcttagcga ctgcaatctg gtattcgact tggtcattcc ccttacctgt acaaccatga
      481 gcaattgtag tcgctcctgt ctgatgcgct atttcaacca attttttaga aataagaggg
      541 cggctcaagg cagataccaa ggggtacttt tgttcatagt aggcatgtga ctggagagct
      601 actagcacat aatctgtagc aaattcgtcc ttaacatcaa tgacataaga ttcgactgcc
      661 ccaaccttaa gagccttatc atggatgaaa tctaagtctt tcccttcacc cacatccata
      721 caaactgcaa caacatcata gtctttcttc agccaggtaa tagcaactga tgtgtctaaa
      781 ccgccagaat aggccaaaat tactttttct ttactcatgt tcttttcctt ctttctattt
      841 ttcaatggac gctttaaagg catcctcaat gagtttgtct aattccccag actccttcaa
      901 cttttgaatg gttttatcga ctgcctcttt caattccttg ctatcttttt tcatggctac
      961 cgcataggaa tcatcttgct ctttttcaaa attgaggtct gcgattgcta aatcaggatt
     1021 attttccaca aatcccttgg caacgggttc ttcaaaaata acggcatcca cttgccctga
     1081 ttttaaatct gtgattaaat tcccattttt aggcagagat acgagggaag aattttgtag
     1141 caaatctttc gccatcgtct cttgaatcga acctttctgc gctccgacct ttttctgcgc
     1201 caaatcgttg acagactgat aagtggctaa atcagatttt ttgacaatga gtttattttt
     1261 tgcagtatag tagggagttg aaaaatcaaa caccttgctc cgttcatctg tcttagaaac
     1321 acctgatatg gcaaggtcag cttttcctga ttgaacgcta gccagtacat tgtcaaaact
     1381 cataggagat agttccaatt cgacacctag ttctgttgcg atagccttgg ctaattcgat
     1441 atctgaaccc acaatctgat ttttcccatc aaccactttt tgatattcaa atggagcaaa
     1501 atctggattg agggctacaa ccaattttcc tttggacttg atggcttcaa ttccagccga
     1561 ttgattgtta ctacaagcaa atagtagggg gagcatcact aaaccaaaca tcgtcatcaa
     1621 caccttcttc atcttattca taacaaagcc tcctttatgt ttattctttt ttattgtata
     1681 aataatactc ctatactcat cctttgtcaa gcctaaattg aaaaaatttt caatttgaaa
     1741 caaaaaaacc tagaaatact acataaaatg tcattcctag gcgtatttat gccatttttc
     1801 tctggaaaac atgagtattc agccagtcaa aaggagctga atgaactcat tttccctcgc
     1861 ccaattcaat gacacgatga cattgttggg ctacataagc atcgtgggtc acaataatga
     1921 ctgttttccc ttctcgattc atctctaaga gaaacttcaa gaccaaatct ctattttcag
     1981 gatccagcga acctgtaggt tcatcggcta aaatcagctg gctgggtttt aagatggctc
     2041 tagcaactgc aattcgttgt tgttcgcccc cagacaactc ggagaccctt tgatgcaaag
     2101 tagctgacaa acctactctc tctaaaatct cttccacctt tttgagcttg tctttcttag
     2161 gcaatttcac atatttcagc gccagcatga gattgtactc gaccgtttca tcatcaatca
     2221 gggcaaaatt ttgaaacaga taagagatat gttcacggat tattgtttgc gacttagcag
     2281 aattaaccgc tagatttgtc tgaccaaaaa tctcataccg tccgctataa tcaccatcta
     2341 tcaaacccaa taaatttaac aaggtcgact tcccactacc actcttacca acaatagcta
     2401 ccaaatcccc ctgatcaatc ctgagagata agttatccaa aatcactttt cccccaatgg
     2461 ttttggtaat atttttcaac tcaatcataa gatgccccct ttcaataact ctactagact
     2521 tcttttctcc atcctagaag ctaagcctag cacaaatagt atatccagac atgtaaaacc
     2581 tgcaaacagt agaagtggta agaacgcatg ggcaaagaaa atcaagacta gaagagggaa
     2641 actatagccc agcaagagca gaacgaggag aggacggtag cgatcgacca gtttccaccc
     2701 cataaacttc ttggtaatga tatccctgcg cttcaataag aaagttgtta ctagtaagaa
     2761 gtaggaaatc atcatgctaa ggagaccaaa caaagcaaag agtaggttaa aattccgaac
     2821 agcatctcta taagaatcca ctttctcttg ttgaatggct tgaatagatg aaaattttaa
     2881 ataatttcca tctgacaatt tctcaactaa ctctgtaatc tctttttgat gttgaaccgt
     2941 attttcaatt ttaatcggat tatttaagcc agttgttgac agggaggctt tctcatccca
     3001 catcatatca gaatcattga ccaagctaat aattggattg gagagatttt cctttcgctt
     3061 atcactatat gggaaaaatg accaatctcc ttcataatag gcaatctcga catccatctc
     3121 ctctatcgtt cgtttttgct gctcttcata cttcatcgaa tgaaaggcaa ttaacttccc
     3181 caagagctga tttttatctt cttcaccttt cgtacttgct ggcatcaaaa taactttttt
     3241 aataccggta tctggtagct tgaatccctt gctctttaga aaattgcgat tggcatagta
     3301 aacatccacc gtatctgtta actgatattg ctgaatctgt tctgattgga caaaattttt
     3361 tacaggaaga ctgctactct gcacatagcc cgcctgcgtt ttttctacca aatcctgata
     3421 aaatcgatag aaataatctg tagatttccc tgaccctgct agctcttctt gccacagatt
     3481 atcattgagt ttgaaggttt ctaaggtcag gtaattacct tgacttaccc actgttgctg
     3541 ataagcaagt tctttgtttt cttgttctaa acttctgccc accccaatca gtaaggccgt
     3601 cagtaaaata gttgtcccta ttttcatcac ataattgaag ataagaccaa atttgaaaga
     3661 tgaaaaacct ttcagcagag agctgattgt cattttttgg attaagaggt aagtcaacca
     3721 actgataaag agataaagct gcaacagcaa aaaatgagac aaccacagca taggaaacaa
     3781 atcttttggc ttataatcaa gcaagaaaaa cacgcctaga ttgatcacaa gagccccacc
     3841 taggaggagg taaaggttgc cttttacaac atcagctaaa acagccctat cttgaaaacc
     3901 aagtaatttt tgtaccccaa ctcttttcat ctccatcatc ggttgataca ctgtcactaa
     3961 cacaagaagc aaaatagcca agacaaaaac aatggcagat aaaagcaaat ctcgatttat
     4021 gacttccact gcacttttgt aggtcggctc tagcaaggta gcctggtcta tcttgaaaaa
     4081 atcgctccat ttctgtacaa tcctatcctt gtccatctct tgtgtagaag ttatcgtata
     4141 gcgaccattt aaactacgag atgtatcctt gatataggtt tgaaaagtca taagctgaat
     4201 aggtttggct tttagaaagg tcggaatcgt accaagttta ttggaaattt ctttattact
     4261 atagactcct tcaccatctg tggtaaaatc aagagaagaa atcccaaact cttggtaggg
     4321 gaaggtatct ttatcaaaaa caccagactt gaccacctca tcaccactgt ctgttttgat
     4381 gatggagact ttatactcct ttgatacatc ctcaaaaaat cgaagaacag acgctgcagg
     4441 ttcgttaata tctttcaaat acaaatccaa agaatctaca gtctttccca tttcttgaat
     4501 ccgaaccact tctcgtgtat agtttacatt aaaaacaaaa aaagtggtac acagaagcag
     4561 gagtaacata cagaaattac tgattttttt cataaaagtg cctccactac agttttccct
     4621 ctccaaatag gagagggaag aattttactc aaatccatag aaatattcca ttcctgttgg
     4681 cggaatcttg gtgagggaag ctctagccca tgcctcagct tctgcacgat ccttagagaa
     4741 tttatttcca tctttaacag ttgctgtatg agagcgagta gaatgtaaat aatcagaata
     4801 accaaaattt cctgaccatc ctactccata gttccattga ccaccatcaa cccatactgc
     4861 caaaacactt gtagaagcaa gtatactaca taccattaaa gatgcaacac taattttctc
     4921 atgatttatt tctcctatta tcgagagcta ttccgtagaa acagctatag taatttgtca
     4981 acaagtatcg tagtccattg gactcacctt ccttctatct catttcattt ttaaacaacg
     5041 aacttactct taactaggag aatagttctc ttctgtatca ggtctttgaa caaccagagt
     5101 agtattaatc acactctaac tattactcaa gaatcagccc aataaacaat atggatagcg
     5161 ctttcaaact tttaaactct tatcccatcc ttttatctat ataataagtg aaaatataat
     5221 aactgtcaag taatcgaagt gaattttata aaaaaaatta caagccaaat ttgcaaagtt
     5281 tacaataagc cgctagggca atcgtctatc agaatgtccg tttatttgtc aataatccga
     5341 gaaaatcttg caacgcttag aagtctataa aaactatcaa catttatatg acttgcgaat
     5401 agcaatcctg ct
//
LOCUS       DBEJNA010000066         5295 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEJNA010000066 DBEJNA010000000
VERSION     DBEJNA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.66"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            29..834
                     /locus_tag="ACL3JB_002012"
                     /pseudo
     CDS             29..834
                     /locus_tag="ACL3JB_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            856..1595
                     /locus_tag="ACL3JB_002013"
                     /pseudo
     CDS             856..1595
                     /locus_tag="ACL3JB_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            1608..2774
                     /locus_tag="ACL3JB_002014"
     CDS             1608..2774
                     /locus_tag="ACL3JB_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0686667.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYV
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            3282..4775
                     /locus_tag="ACL3JB_002015"
     CDS             3282..4775
                     /locus_tag="ACL3JB_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0686668.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            4788..>5295
                     /locus_tag="ACL3JB_002016"
     CDS             4788..>5295
                     /locus_tag="ACL3JB_002016"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686669.1"
                     /translation="MKKVKLGEILSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLL"
BASE COUNT         1686 a          936 c         1124 g         1549 t
ORIGIN      
        1 aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc taaaaatgaa
       61 agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc
      121 taaagattat gagaaagata cagaccgttc ttatcctgtt gtatactttc atgacgggca
      181 aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta tcccagctat
      241 caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg
      301 gcggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag ggcagcagtt
      361 tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga
      421 tgagacctat cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg
      481 aggcaatatt acccagttta tcggtttgga ataccaagac caaattggtt gcttgggcgt
      541 tttttcatct gcaaactggc tccaccaaga agcctttaac cgctatatcg agtgccagaa
      601 actatcgcct gaccagcgca tcttcatcta tgtaggaaca gaagaagcag atgatacaga
      661 caagaccttg atggatggca atatcaaaca agcctatatc gactcgtcgc tttgctatta
      721 ccatgatttg atagcagggg gagtacatct ggataatctt gtgccatcca tagtgaaatc
      781 ccttggtcag aaaatctacc agattgtctg agattttttg cagaaaaatg gtaagttaag
      841 aaaggaaaaa acgaaatgca tattgaacat cttagccact ggagtggtca tcctaaccgt
      901 gaaatgtacc ttaaccgtta tggacatggt gggattccag ttgtggtctt tgcttcatca
      961 ggtggtagtc acaacgaata ctatgatttt ggcatgattg atgcctgtgc ttcctttatc
     1021 gaggaaggcc gtgtccagtt ctttacccta tctagtgtgg atagtgagag ctggttggct
     1081 acttggaaaa atgctcatga ccaagcggaa atgcaccgtg cctacgaacg ttatgtgatt
     1141 gaggaggcca ttcttttatc aagcacaaga caggttggtt tgatggcatg atgacgacag
     1201 gttgctctat gggagcctat catgcactta atttcttcct ccagcatcca gatgtcttta
     1261 ccaaagtgat tgctctcagt ggtgtttacg acgcacgttt ctttgtcggt gattactaca
     1321 acgatgatgc tatttaccaa aactcgccag tagattatat ttggaaccaa aacgacggct
     1381 ggtttattga ccgttaccgt caggcagaga ttgtgctgtg tacggggctt ggagcctggg
     1441 aacaagatgg tttgccatcc ttttacaagc tcaaagaagc ctttgacaag aaacaaattc
     1501 cagcctggtt tgctgaatgg ggacatgatg tcgcccatga ctgggaatgg tggcgtaaac
     1561 aaatgcctta tttcctcggt aatctctatt tataaaagga gttacctatg aattaccttg
     1621 ttatttctcc ctactatcca caaaactttc aacagtttac catcgaacta gctaataaag
     1681 gcatcacagt cttgggaatt ggtcaagagt cttacgagca attggatgag cccttgcgca
     1741 atagcttgac cgagtatttt cgtgttgata atcttgagaa catagatgaa gtcaaacgtg
     1801 cagttgcttt tctcttttat aaacatggtc caattggccg catcgagtct cacaatgaat
     1861 actggcttga gctagacgca acactcagag aacaattcaa tgtttttggt gccaaaccag
     1921 aggatctcaa aaagacgaaa tataagtctg aaatgaagaa acttttcaaa aaagcaggtg
     1981 ttcctgtggt acctggagct gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag
     2041 aaatcggtct tccaatgatt gccaaacctg ataatggagt gggagcagcc gcaaccttta
     2101 aacttgagac agaagacgat atcaatcact tcaagcaaga atgggaccat tcaacccttt
     2161 atttctttga aaaatttgtc acttccagcg aaatctgtac ctttgacggg ctcgtggaca
     2221 aggatggaaa gattgtcttc tcaacaacct ttgactacgt ctatacaccg cttgacctca
     2281 tgatttataa gatggacaat tcttattatg tgctcaagga tatggatcct aaactgcgca
     2341 agtatgggga agcaattgtc aaagaatttg gtatgaaaga acggtttttc catattgagt
     2401 tcttccgtga gggggacgat tatattacca tcgagtacaa taaccgccct gcaggtggtt
     2461 ttaccattga tgtttataac tttgctcatt ccttggacct ttatcgtggc tatgcagcta
     2521 ttgtcgcagg agaggagttc ccggcgtcag actttgaaac tcagtattgt ttggctactt
     2581 ctcgccgtgc aaatgctcac tatgtttatt cagaagagga tttgcttgcc aaatatagcc
     2641 agcagttcaa ggttaaaaaa gtcatgccag ctgccttcgc ggaacttcaa ggagattacc
     2701 tgtatatgct gaccactccg agtcgacaag aaatggagca gatgattgca gatttcggac
     2761 aacgtcaaga ataagaacta tcggattaag gaaattcact cccttaatcc ttttgttttg
     2821 tctggtaaaa aataagagca tcctaacaag gtagctatca taaaacttgt tcgataacta
     2881 tttgaagcag gattaggtgg ctagaaattg aattttaaca tttcaattga gtcatagtat
     2941 tgtgttttcg tatccttaaa tcagctaaaa ggatccatga cgacacctat acgatatagt
     3001 tttcaggata ccaaacaagt ctattaatac tcaatgaaaa tcaaagagca aactaggaag
     3061 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cagagtcagt
     3121 atcatatacc tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
     3181 aatattcagg tgacgcatag atatagttaa ttgaagcttt gtttgaaatc tgataaaata
     3241 atgatattac taagttctaa aaactaaaga aaagggaaga tatgattaca ggcgaattaa
     3301 aaaataaaat cgatcagctg tgggaaattc tttggacaga aggaaacgca aatcctttaa
     3361 caaatattga acagttgact tatctcttat ttatgaaaga tttggatagt gtcgagcttg
     3421 gacgtgaaag tgatgctgaa tttctaggga ttccttatga gggagttttt ccaaaagata
     3481 aacctgaata ccgttggtca acttttaaaa atataggaga tgctcaggaa gtttatcgtt
     3541 taatgactca ggagattttt ccgtttatta aaaatctcaa gggggataca gatgatacag
     3601 ccttttcacg atatatgcga gaagctattt ttcaaataaa taaacctgct acgcttcaaa
     3661 aggcaatttc tatcttagat gtttttccaa ctaggggatt agatgtagat tttgataatg
     3721 acaaacaaag tattactgat atcggagata tctatgaata tctgttatca aaattgtcga
     3781 ccgcaggtaa aaatggacag ttccgtacac ctcgtcacat catcgatatg atggttgagt
     3841 tgatgcaacc gactatcaaa gatatcatct cagatcccgc tatgggttct gctggcttct
     3901 tagtatctgc tagccgttac ttaaagcgta agaaagatga atgggaaacc aatacagata
     3961 atatcaatca ttttcataat cagatgtttc atggaaatga tacggatacg actatgttga
     4021 gacttggggc gatgaacatg atgctacatg gagtagaaaa tccacaaatc agttaccttg
     4081 actcgctgtc tcaagataat gaagaagccg ataaatatac tttggtttta gcaaatcctc
     4141 cttttaaggg ctcacttgac tacaattcaa cctctaatga ccttcttgca accgtaaaaa
     4201 ccaaaaaaac agaattactc tttctttctc ttttcttgcg aactttaaaa ccaggtggac
     4261 gagcagcagt tatcgtacct gatggtgtcc tttttggttc gtctaaagct cataaaggaa
     4321 ttcgtcagga aattgtagag aatcataagc ttgatgctgt aatctcaatg cctagtggtg
     4381 tgttcaagcc ttatgctgga gtttcaactg ctattctcat ctttacaaaa actggtaatg
     4441 gtggtactga caaagtctgg ttttacgata tgaaagcgga tggtttaagt ttggatgata
     4501 agcgacaacc gattagcgac aatgatattc cagatattat cgaacgcttt catcatcttg
     4561 aaaaagaagc agaacgtcag agaacggatc aatctttctt tgttccagtt gctgagataa
     4621 aggaaaatga ttatgatttg tctatcaata aatataaaga gattgagtat gaaaaagttg
     4681 agtatgaacc aacagaggtc atcttaaaga aaatcaatga tttagaaaaa gaaattcaag
     4741 ctggcttggc tgaattagaa aaattactca agtagggagg tggctgtatg aaaaaagtga
     4801 agttggggga aatcttatct ctaaaaaaag gaaagaaagc cactgtactt gctgaacaaa
     4861 caactctaag ccaacgttat attcaaatag atgatttaag aaataataat aatttaaaat
     4921 tcactgaaag tttaaatatg actgaagcac tcccagatga tattctaata gcatgggatg
     4981 gtgctaatgc aggaacagtt ggttatggat tatcgggagc tgttggtagt acaattacgg
     5041 tcttaaaaaa gaatgagcga tacaaagaaa aaattatatc agattacttg ggagtctttt
     5101 tggaaagtaa atcgcagtat ttacgagatc attcaacagg tgcaacaatt cctcatttaa
     5161 acaagaatat attacttgat ttacaattag aattgctagg tatcgaagaa caagagaaca
     5221 ttatctgtat tcttaatacg attaaaaggc ttattactaa aagaaaattg cagttagatg
     5281 aactaaactt gctcg
//
LOCUS       DBEJNA010000067         5212 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEJNA010000067 DBEJNA010000000
VERSION     DBEJNA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.67"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(360..1088)
                     /locus_tag="ACL3JB_002017"
     CDS             complement(360..1088)
                     /locus_tag="ACL3JB_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0686670.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1246..2655
                     /locus_tag="ACL3JB_002018"
     CDS             1246..2655
                     /locus_tag="ACL3JB_002018"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0686671.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2673..3968
                     /locus_tag="ACL3JB_002019"
     CDS             2673..3968
                     /locus_tag="ACL3JB_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0686672.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3973..4281
                     /locus_tag="ACL3JB_002020"
     CDS             3973..4281
                     /locus_tag="ACL3JB_002020"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0686673.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4278..4586
                     /locus_tag="ACL3JB_002021"
     CDS             4278..4586
                     /locus_tag="ACL3JB_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0686674.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1756 a          879 c          949 g         1628 t
ORIGIN      
        1 tgggagattg aaattcattt ctagcaattt gttagaagtc acagtctact attctaacca
       61 cagtatacta tatgtgttac aagaaaagac tcaaaaactt ctcgtcagtg taagaatgtt
      121 tgaaacacta tttaaaacta aataactata agaagtagat caggtgaaca atttcagtac
      181 ctactctata agctatacga agatattttt caacatgatg gataaaacga tcactctttt
      241 aaagccatct tatttagaaa agagaaacca tttaagcata gatgggacct tcttgccctg
      301 ttttaaattt ttcttaaact agagtctgta aaagattggc ttcattttca cattttctcc
      361 taggaggaat gtcgtaatgc aaaagaatta aattcaaata aatcatagcg atgacgacta
      421 atcgagtact caaacggagt tccgttatcc aaataagcca cttgttctac ttcaaatacc
      481 ggttccgttg gaaggagctg caagtaatgt tgctcatttt ctgaactaga agaagctcgc
      541 aagatttttg tagcactggc aatatgcaat cctaactttc cttcaatgta attgtaaatc
      601 gatttttgta aaatatcttc agtaatacct ggaataacat cggtactcat ataagtttgt
      661 tccagaacat aaggtttacc gtcaataata cgcagacggt aaatattata aactggactc
      721 tgcaaagcga cctgtagttt ttctgctaaa aattcatttg caaattctaa tttgaagtga
      781 ataatcctcg agtcaattgt agaatgagca tcttcagata tttttgtcag tccccggata
      841 tctctttctg gaacgattaa ttttcttttt gagctgccac gagagagaac aaaggttccc
      901 tgcccacgtt ttctaaaaat taagccctca gaaactaaca agtctaaagc ttttttgatc
      961 gtcattcgac tacaggcaaa ctgtttagct aatgtcattt catcaggcaa ttgttcgttc
     1021 atggtatatt tattacaaag aatcttttca cgaatctcat tgtaaataaa taaatatttt
     1081 gtactcattt aatctggttc tctctataat attctaatag tagtataaca aagttcaaga
     1141 aatgaggcaa acacaagata tgtatcaaca atttttaaaa atgtctagac aaattttaaa
     1201 attatgctat actttatgta tagaataata gaaaggaggt tgagcatgaa aaaaaagtta
     1261 gtatttccta atctgttttg gtggggagct gcttctagcg gacctcagac agaaggtcaa
     1321 tatggaaaag tacatgaaaa tgtgatggac tactggttca aaacgcatcc agaagatttt
     1381 ttcgataatg tcggacctct tgtagccagt aacttttttc atacttacac cgaagatttc
     1441 cacttgatga aggaaattgg agttaattct ttccgcactt ccatccaatg gagtcgactc
     1501 atcaagaatt tagagacagg tgagcctgat ccaaaaggta ttgctttcta caatgccatc
     1561 attgaagaag ctaaaaagaa ccagatggat cttgtgatga atttacatca ttttgattta
     1621 ccagtggaac ttcttcaaaa atacggtggt tgggaaagca aacatgtagt ggagttattc
     1681 gtgaagtttg ccaagactgc tttcacatgc tttggagata aggttcatta ctggacaact
     1741 ttcaatgagc caatggtcat tccagaagca ggatacttat atgctttcca ttatccaaat
     1801 ctaaaaggaa agggaaaaga ggccgtacaa gtcatctata atctaaacct tgctagtgca
     1861 aaagtgattc aactatatcg ctcattagaa cttgatggaa agattgggat tattttaaac
     1921 ttgacacctg cttatccaag aagtaattct ccagaagact tagaagcaag tcgatttaca
     1981 gaagacttct ttaacaaagt cttcttgaat ccagctgtta aaggaacttt cccagaaaga
     2041 ttggtaaaac agctagagag agatggcgtg ttatggagtc ataccgaaaa agagcttcaa
     2101 ctgatgaaat caaatacggt tgattttctt ggagtaaact actaccatcc aaaacgtgtt
     2161 caagcacaag caaatcctga ggaatatcag acgccctgga tgccagacca atacttcaaa
     2221 gagtatgaat ggccggagcg tcgcatgaat ccatatcgtg gttgggaaat ttttccgaaa
     2281 gccatttatg atattgctat gattgtgaag gaagaatatg ataatattcc atggtttatc
     2341 agtgaaaacg gaatgggtgt tgaaaacgaa gcacggttta tcgatgaaaa tggagttatc
     2401 gatgacgtgt atcgtattga attttatgaa gaacatttaa gatggctaca taaagccatt
     2461 gaagagggaa gtcactgttt tggataccac gcttggaccg catttgattg ctggtcttgg
     2521 aataatgcat ataagaatcg ttacggattt atctccgttg atttagaaac gcaaaagaga
     2581 accatcaaga gctcaggaag atggtatcgc aaagtaagtg acaataacgg ttttgaagta
     2641 gaaattgagg agtaaagaga ggagatattc agatgaaaaa ctcaaaattt atagatcaat
     2701 ttgccacctt tgctggtaaa ctagggaacc aaattcattt aaaaacccta agagatgcat
     2761 tcgtaacagt aatgccatta tatattttgg caggtttaat cgttcttttg aacaacacgg
     2821 tatttaagtg gattttccaa ggggatacat taacaagatt ccaatattgg ggaataacaa
     2881 ttgcaaacgg tactttaagt atttcaggta tgattattgc tgtaatggtt ggttatttct
     2941 tagctaaaaa cagagatttc gaaaacccgt tagcagcatc aatgctatca ttagtttctt
     3001 taattgtgat gatgccaaat acagtttctg tagttcctga cggagcaaaa gatgcggtaa
     3061 acatttcagg tgttctttca ttcaacaaca caggtacagg cgcaatgttc gccggggtta
     3121 tcgtagcgat tattgcaaca gaattattca ttgaattatc aaacgttaaa gctttacaaa
     3181 tgaaccttgg tgaaaatatt ccaccagctg ttagtagatc atttagcgta ttacttccag
     3241 tcatgaccgt catctcctta tttggggttg tttcagcatt attattcaat ataactggaa
     3301 tgaacttaat ctcaatcatt acaatcttta ttcaagaacc aattcgtcat attggtacaa
     3361 gcttaatcgg ggtcattatt atttactctt taggaaatat gttatggcta tttggtattc
     3421 accaagcagt tatttacagt gccatcctag aaccattact attaattaac attactgaaa
     3481 acatcactgc agcaaataat ggacaagcca ttccacacat catcaaccta tcacaaatac
     3541 aaacattcgc tttaatgggt ggtagtggat ctacattatg tttattaata gcaacattct
     3601 tagtgagtcg caatgctgtc tctaaaaacg tggctaaatt atcttttgga cctggtatct
     3661 tcaatatcaa tgaaccagta ttattcggtt acccaatcgt ttataacatt tcattagcta
     3721 ttccatttat cacagttcca gtccttggta ttttaatcag ctacttagca acagttacag
     3781 gattcatgag tcctgcattt atacaagttc cttggactac accagtattc ttaaatgcat
     3841 ggttagcaac agcaggggac gtgagagcag ttctagttca attcatcatc tttgcacttg
     3901 gagttcttct atacattcca tttatcaaag ttaatgacaa agttgttgaa caagaaatgg
     3961 aaggttaaga ttatgaaaca aattttatta gtatgtaatg cgggaatgtc gacaagtatg
     4021 cttgttaaaa aaatgcaaca aagtgcgact gaacgtggga ttgaaatctc tatccaagca
     4081 aaatcaatga cagaagctaa aaagaatatc catgaagcag atgtcattct aattgggcca
     4141 caaattcgtt atgagttact tgctgtgaaa gaaattgcag gaaatatccc tgtagatacc
     4201 attgatatgc gggattacgg aatgatgaat ggagcaaaag ttctggaaca agcacttgca
     4261 tggataggag aaataagatg acagaagaaa tggaatatat ctgttttcag ctcattgcca
     4321 atagtggagc agccaaatca tcctttattg aagccatcca actagctaag gcaggaaatt
     4381 taaaagaagc gaaaattaaa gttgaagaag cggaagactc cttagtagaa gcgcacaaga
     4441 ttcactctaa tctcatacaa aaagaagcta ctggagaaaa aataggattc tccttgctat
     4501 ttatgcatgc agaagaccaa atggcttcaa cagagattat tcagttgcta tctaaagaat
     4561 tcatcgatct ctatcaaaat aaataggaac actgtcattc ccatctgtct ttattaatga
     4621 cgactacatt gtaggaacct ccaaaagttg gacaaaatga ttgaaaggat tggatcctgc
     4681 attacacaag atccaatcct tttcttttac tctagttttt ataatatgtt gaatctagaa
     4741 tagtccactg tagtttctaa aaaattgctg gaaatggatg ttaagctcca atttatttgt
     4801 ttatatctta tttcagttta ctatactagc ttattattct agtgaaaaat tgaatgagcc
     4861 actatttatt taatatgtat gatgagggaa tgactcaaaa acttcttgtc gatataagaa
     4921 tatctgagat agtattttaa aacgaaagga ctataaaagc tcatttcctt cgcacttatt
     4981 ttatagagat ctatcattat actctttaga aatcaaaaag caacacacct tgtcatcgtt
     5041 ttatcgtaaa tctgttaatg agggggctag tcttatctgc aatctcaaat cagtgttttg
     5101 agctgaatgg cactcgtttt ctagtttgct ctttgatttt aattgggcct tagtaaatac
     5161 tactcttaaa ttaaactata gtgaattgaa ataagatgtg aacaactcta tc
//
LOCUS       DBEJNA010000068         4774 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEJNA010000068 DBEJNA010000000
VERSION     DBEJNA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.68"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            41..1867
                     /gene="glpO"
                     /locus_tag="ACL3JB_002022"
     CDS             41..1867
                     /gene="glpO"
                     /locus_tag="ACL3JB_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0686675.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1937..2641
                     /locus_tag="ACL3JB_002023"
     CDS             1937..2641
                     /locus_tag="ACL3JB_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0686676.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2938..3141
                     /locus_tag="ACL3JB_002024"
     CDS             2938..3141
                     /locus_tag="ACL3JB_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686677.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3228..3836)
                     /locus_tag="ACL3JB_002025"
     CDS             complement(3228..3836)
                     /locus_tag="ACL3JB_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686678.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            3968..4159
                     /locus_tag="ACL3JB_002026"
     CDS             3968..4159
                     /locus_tag="ACL3JB_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686679.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNK"
BASE COUNT         1446 a          947 c         1049 g         1332 t
ORIGIN      
        1 actggcagaa taaagcgatt tagttagaaa gtgtgtaaat atggaatttt caaagaaaac
       61 acgtgaattg tcaattaaaa aaatgcagga acgcaccctg gacctcttga ttatcggtgg
      121 aggaatcaca ggagctggtg tagccttgca ggcggcagct agcggtcttg agactggttt
      181 gattgaaatg caagactttg cagaaggaac atctagtcgt tcaacaaaat tggttcacgg
      241 aggacttcgt tacctcaaac aatttgacgt agaagtggtc tcagatacgg tttctgaacg
      301 tgcagtggtt caacaaatcg ctccacacat tccaaaatca gatccaatgc tcttaccagt
      361 ttacgatgaa gatggagcaa cctttagcct cttccgtctt aaagtagcca tggacttgta
      421 cgacctttta gcaggtgtga gcaacacacc aactgcgaac aaggttttga gcaaggatca
      481 agtcttggaa cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct
      541 tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga
      601 cggtgccctc attgccaacc acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa
      661 gattacaggt gttgtagctc gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg
      721 tctggttatt aatacaacag gtccttggag tgataaagta cgtaatttgt ctaataaggg
      781 aacgcaattc tcacaaatgc gcccaactaa gggagttcac ttggtagtgg attcaagcaa
      841 aatcaaggtt tcacagccag tttactttga cacaggtttg ggtgacggtc gtatggtctt
      901 tgttctccca cgtgaaaaca agacttactt tggtacaact gatacagact acacaggtga
      961 tttggagcat ccaaaagtaa ctcaagaaga tgtagattat ctacttggca ttgtcaacaa
     1021 ccgctttcca gaatccaaca tcaccattga tgatatcgaa agcagctggg caggtcttcg
     1081 tccattgatt gcagggaaca gtgcctctga ctataatggt ggaaataacg gtaccatcag
     1141 tgatgaaagc tttgacaact tgattgcgac tgttgaatct tatctctcca aagaaaaaac
     1201 acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg agaaatattt
     1261 ggatccatct gcagtttctc gtgggtctag cttggaccgt gatgacaatg gtcttttgac
     1321 tcttgctggc ggtaaaatca cagactaccg taagatggct gaaggagcta tggagcgcgt
     1381 ggttgacatc ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt ctaaaactta
     1441 ccctgtttca ggtggagaat tgaacccagc aaatgtggat tcagaaatcg aagcctttgc
     1501 gcaacttgga gtatcacgtg gtttggatag caaggaagct cactatctgg caaatcttta
     1561 cggttcaaat gcaccgaaag tctttgcact tgctcacagc ttggaacaag cgccaggact
     1621 cagcttggca gataccttgt cccttcacta tgcaatgcgc aacgagttgg ctcttagccc
     1681 agttgacttc cttcttcgtc gtaccaacca tatgctcttt atgcgtgata gcttggatag
     1741 catcgttgag ccagttttgg atgaaatggg acgattctat gactggacag aagaagaaaa
     1801 agcaacttac cgtgctgatg tcgaagcagc tctcgctaac aacgatttag cagaattaaa
     1861 aaattaagaa aaaataaaag aggtggaggg cagcattcct tgtcgcccgt cccttctttt
     1921 taatggagac agaaagatga tgaatgaatt atttggagaa tttctaggga ctttaatcct
     1981 gattcttcta ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca agagcaatag
     2041 ctcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg cagtctttgt
     2101 atctggcaag ctcagtccag ctcatttaaa tccagctgtg acagttggtg tagctttaaa
     2161 aggtgacttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg caggggccat
     2221 gctgggtcag attttggttt ggttgcaatt caaacctcac tatgaggcag aagaaaatgc
     2281 aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg tatcaaactt
     2341 gattagcgaa atccttggaa cctttgtttt ggtgttgaca atctttgctt tgggtcttta
     2401 cgattttcag gcaggtatcg gaacctttgc agtgggaact ttgattgtcg gtatcggtct
     2461 atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg gacctcgtat
     2521 catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt acgcttggat
     2581 tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct cacttttcta
     2641 gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc gtactcaagt
     2701 acagcttgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaaaacaat
     2761 tattttgata gagcttgggc aagagcccaa tttcagcaaa aaatgaagta aatcttctca
     2821 taataaaacg catcatatca agcacgaaaa ttccacgagg tcaactacag tcagaaagct
     2881 gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc aagcacctgc aagcaacgtg
     2941 ccgaaatggt caaatcctga ttatgtcaac gaattagacc caaaaatcgt tgatatgcta
     3001 gtagaatttc acaagtcaca aggcactttg gaaactcccg aggcgcaagc agaaatcgcc
     3061 caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg aggataaaaa acaagagctt
     3121 ttgaaccgct tgaacaaata gagtttcgca agtattatgc ttacaaatta cttgagcaat
     3181 taactaaaat ataaaccctg cctttatatc taggcagggt ttatatttta gaaattcacg
     3241 taggttgtta cggtttttac atacccagta tagtttgagt ttctatagta ttcagtgata
     3301 aacttccatt ttctttgagc aacatggata taagtacttg ttatgtagta tggatatggg
     3361 ctttgtgaat ccaagtaaga ctgataagct tgtataccaa aatatgctcc accaattatt
     3421 gcaccccatg gaccccccaa taaagcacct atcctaccaa tcatataact gattccagca
     3481 ccagtcatga agttagcgaa tgtgttagct tgtttattcc catgtattgt gttgacgtaa
     3541 ttccaaacat taggatcgta tgatctaaaa gatatattta ggtcgatttc attcttttga
     3601 taagccatat aaaatgcccc attgatatag acgccgtcag cacgtcgttc aatagtgtct
     3661 acacttccat ctggattgac aacctcaaga acttcatcgc ttaaaatatt tacttgcgta
     3721 tctccgaacc gcactgatga gccattctca aactgagcct caccagatac aactttagag
     3781 tttgccgata agctatcatc agcaaaaaca acaagcgacg gggaaatgct agacatacag
     3841 aaaacagaca taactagcaa acacatgcat ttaaacatct tagacataac ggaaactctt
     3901 ttgtattttt gatttttttc aacttttatt atacaataaa accaaataaa aagaaagcgg
     3961 taacaatatg cttaatgcga aaatttttta tatattttta tgtttgatcg ttatcgaaac
     4021 tacaggcttg ttgttgttga aaagaggtct cgaaatgggt tatttagaca cagaagctat
     4081 tatcctcgca gttttttcat ttgcttttta caacctatgt tcattcgctt gggtctgctc
     4141 tacaataaaa aataaataga cgtattttca aaaaaaaaat gcatatttat attagcaaaa
     4201 tgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat ctgaggtgta
     4261 agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc ctgactatcg
     4321 tgaggtagca gggagaggaa gggatagcga aatcgtggct ctacgaacag gaacgtgata
     4381 gtaaggcgta tatagcggat aaggaggctt caaactctaa agtccaaaaa ggtagtcgta
     4441 acctatatgt gtaaatcacg agagtaattg aattcggact aaggtttgtg tgaaaaagat
     4501 aaatctttct agagtctaaa gactctgcgt cagatttcct attttcactg taacctttta
     4561 acgtcctcat atcttgtata aacgaggaaa gatgtacgac ttatcccgtg aggtttcatg
     4621 agcgctgaaa gcgtagtaac aacgaatcat gagaagtcag ccgagcccat agtagtgagg
     4681 aaacttctgt agtggaagtg gagcgaaggg gtgaatactc aaacagtctg gggagagact
     4741 gtttgaggtc tgtcgctaga aagagaaaac gaca
//
LOCUS       DBEJNA010000069         4552 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEJNA010000069 DBEJNA010000000
VERSION     DBEJNA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.69"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            450..1796
                     /gene="gdhA"
                     /locus_tag="ACL3JB_002027"
     CDS             450..1796
                     /gene="gdhA"
                     /locus_tag="ACL3JB_002027"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0686680.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHGGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVDQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2302..2472)
                     /locus_tag="ACL3JB_002028"
     CDS             complement(2302..2472)
                     /locus_tag="ACL3JB_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686681.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2485..3057)
                     /locus_tag="ACL3JB_002029"
                     /pseudo
     CDS             complement(2485..3057)
                     /locus_tag="ACL3JB_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3080..3885)
                     /locus_tag="ACL3JB_002030"
                     /pseudo
     CDS             complement(3080..3885)
                     /locus_tag="ACL3JB_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            4141..>4552
                     /locus_tag="ACL3JB_002031"
     CDS             4141..>4552
                     /locus_tag="ACL3JB_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0686682.1"
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIE
                     FLDCNQTTIWQNVKKYEEFGLDSLLQETRGGRNHAYMTVEEEKVFLARHLKATEAGEF
                     VTIDALFQAYKKELGRSYTRDAFYQLLKRHGWRNI"
BASE COUNT         1411 a          843 c          776 g         1522 t
ORIGIN      
        1 ttgtttcatt ttactataga acgatttgaa ggcgtttatg atatttagct gtactagagt
       61 tttttaaaag tgttttgatg gtttggattt cttctttaat tgatttcata ttactattat
      121 ataatgcttt ttgattttag tctggtataa atattgcttt cctccaaaat ggtcatagtt
      181 ttactggcaa atctaacata tcacggataa attaacaagt gatttctgaa ttactaaaca
      241 ttttcttttc ttatagcata ccatacttta agattttgtc tttaagaaag atatttccaa
      301 gaaaaacgtt cgttttttta tctattttca aaaaaaccaa aaactgaatt gaaagaattt
      361 ttagaaaatt tctgtttttt ctttacagtg aaaaaaaatt ctgctataat gtcttatgta
      421 ataaaatatg acaataaaag gagaacgata tgacatctgc taaagaatat atccaaagcg
      481 tgtttgaaac tgtgaaagct cgtaacgggc acgaggctga attcctccaa gctgttgaag
      541 aatttttcaa cactttagaa cctgtatttg aaaaacaccc tgagtatatc gaagaaaata
      601 tcttggcacg tattactgag cctgagcgcg tggtttcttt ccgtgttcct tgggttgacc
      661 gtgatggaaa aattcaagta aaccgtggtt accgtgttca attcaactca gctgttggac
      721 catacaaagg tggacttcgt ttccacccaa ctgtaaacca agggatcttg aaattcctcg
      781 gatttgaaca aatctttaaa aatgtcttga ctggacttcc tatcggtgga ggtaaaggtg
      841 gatcagactt cgatcctaaa ggtaaaacag atgctgaagt gatgcgcttc tgccaaagct
      901 tcatgactga attgcaaaaa cacatcggac catcacttga cgtacctgct ggtgatatcg
      961 gtgttggtgg acgtgagatt ggttaccttt acggtcaata caaacgtctt aaccaatttg
     1021 atgctggtgt cttgactggt aaacctcttg gatttggtgg tagcttgatt cgtccagaag
     1081 caactggtta cggtttggtt tactatactg aagaaatgct caaagctaac ggtaacagct
     1141 ttgctggtaa gaaagtcgtt atttcaggtt ctggtaacgt tgctcaatat gctcttcaaa
     1201 aagcaactga actcggtgca actgttattt ctgtttctga ctcaaatggt tatgtcatcg
     1261 atgaaaatgg tatcgacttc gatcttttgg ttgatgttaa agaaaaacgt cgtgctcgtt
     1321 tgactgagta tgcagctgaa aaagcaactg ctacttatca tggaggttct gtatggactt
     1381 acgctggtaa ctatgatatc gctcttccat gtgcgactca aaacgaaatc aacggtgaag
     1441 cagctaaacg tttggttgat caaggcgtta tctgtgtatc tgaaggtgcc aacatgccga
     1501 gcgaccttga tgccatcaaa gtttacaaag aaaatggtat cttctacgga cctgccaaag
     1561 ctgccaacgc tggtggtgta gccgtttcag cccttgaaat gagccaaaat agtcttcgcc
     1621 tctcatggac tcgtgaagaa gttgatggcc gtctcaaaga catcatgaca aacatcttca
     1681 acacagctaa aacgacttca gaaacatacg gtcttgataa agactacctt gcaggagcaa
     1741 acattgctgc ctttgaaaat gtagcaaatg ccatgattgc acaaggtatt gtttaagatt
     1801 tatttactca atcctcaatc actacgattg gggattttta gcttgaatta aaaaattgga
     1861 aaatctaatt aaataaaatg aaatgaaata aaaactgaac aaattgattg cggaattcaa
     1921 accaatttct aacatacttc tagaaattaa tttgactttt ctaatcgatt tgttcatatc
     1981 ttatttcaat ttactatact tacttaaccc tttttatact caatgaaaat caaagagcaa
     2041 actaggaagc gagccgcagg ctgtacttga gtacggcaag gcaaagctga cgtggtttga
     2101 agagattttc aaagagtatt aaacaaaaag aaaaaccgct actcctaaga atagcaattt
     2161 aatcatgttt ttaagctact actgtagttg ctctattatt taagtgttat gaataacttc
     2221 aatatcttta aagctttttg ttagatttat aatttcaact atagccatct ctactcctta
     2281 gtttacagca aaaaattatg cttaattctt attgtttttg taaacaatca gcgaacccaa
     2341 tactattcca ttcaacaagc ctaaagaaat accatattca actggaaaat ctaaaaaaat
     2401 tgcaaacact attccaatca tcacccctag tgaggctatt gttaaaatta catattcatt
     2461 ttctttcttc attttcttta cacctcattt cctttttgta tataagctgt agtactctcc
     2521 accaagagtt attaagtact tatgatttcc tgactcaaca atcttaccac ctttcattac
     2581 aaaaataata tccgcatcct taatcgttga caatctatga gctataatta tttgagtaca
     2641 accctgactt tgtatatact ttgttattct ttcctcatta atagtgtcta atgcactagt
     2701 tgcttcatct aaaattacaa tactaggatt atttattaat gcacgtgcca gtgctatccg
     2761 ttgcctttgc ccacctgaaa tatttgaccc catctctgag atgatagtat taaatttcat
     2821 cggcatagcc atgatttcat catagatttg aactgcttta caaacttcct ctatcttttg
     2881 tgaagtaact tcgtgcttta aagttatatt atcaagaata cttcggttca ataaaaatga
     2941 atcctgtgga actactccta aattttgact taatattttt ttatctattt gattaatatt
     3001 tataccataa aataaaactt ttcctgtatc aatcttatat aatcctgatg gtatttttga
     3061 taatagactt cctgcaaaac tagaatccta gttcatgatt gataatacca acaatcaaat
     3121 tcatccgtaa tccgaagcgt ttacgatgat ttcgataggt tgttgaaaac attttaagcg
     3181 tttttacttt ggcaaagatg ttctcaacct tgcttctctc cttagatagc acatggttac
     3241 aggctttatc ttcagctgtt agcggcttga gtttgctgga tttacgtgga gtttgtgctt
     3301 gaagatatat cttcatgagc ccttgataac cactgtcagc caagatttta ccagcttgtc
     3361 cgatatttct gcgactcatt ttgaacaact tcatatcatg acaatagttc acagcgatat
     3421 ccaaagaaat aattctccct tgacttgtga caatcgcttg agtcttcata gcgtgaaatt
     3481 tctttttacc agaataattc gctaattctt tttttaggtc gattgatttt tacttccgtc
     3541 gcatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgc aacaccacct
     3601 ttgaacaaga gttacttcaa cccattggct ccgacggatt aagttgcttt cgtgaatacc
     3661 aagatcagcc gaaatttctt cataagttcg atattctcgc acatattgaa gagtggccat
     3721 aagaaggtct tctaggctta atttaggttt tcgcccacct tttgcgtgtt taagttgata
     3781 agctgttttt aatacagcta acatctcttc aaaagtcgtg cgttgaacac caacaagacg
     3841 cttaaatcgt gcatcggtta gttgtttact tgcttcataa ttcatagaac tattatacca
     3901 tattttgttt cgcaggaagt ctattgaaaa atctccagac tagagaactc acggatagtt
     3961 cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca cggtaaatag
     4021 gcctctaaaa cctctttgtt tacgagagtt tcctcgtttg gaagacattc tagaagatag
     4081 gatagatatt tctcgctatt tatactagac taaaatcaaa aagcattata caatagtgat
     4141 atgaaatcaa ctaaagaaga aatccaaacc atcaaaacac ttttaaaaga ctctcgtaca
     4201 gctaaatatc ataaacgcct tcaaatcgtt ctatttcgtc tgatgggcaa atcttataaa
     4261 gagattatag agtttttaga ctgtaatcaa acaacgattt ggcaaaatgt aaaaaaatat
     4321 gaggagttcg gactcgactc tctccttcaa gaaacacgtg gtggtcgtaa ccatgcatat
     4381 atgacagttg aggaagagaa agtctttctt gcccgtcatt tgaaggctac agaggcagga
     4441 gaatttgtta caattgatgc cttatttcag gcttataaaa aggagttagg tcgttcctac
     4501 acacgtgatg ccttctatca actgttgaag cgccatggtt ggcgaaatat ta
//
LOCUS       DBEJNA010000070         4478 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEJNA010000070 DBEJNA010000000
VERSION     DBEJNA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.70"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            163..816
                     /gene="rr06"
                     /locus_tag="ACL3JB_002032"
     CDS             163..816
                     /gene="rr06"
                     /locus_tag="ACL3JB_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0686683.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            813..2153
                     /gene="hk06"
                     /locus_tag="ACL3JB_002033"
     CDS             813..2153
                     /gene="hk06"
                     /locus_tag="ACL3JB_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0686684.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            2236..2763
                     /locus_tag="ACL3JB_002034"
     CDS             2236..2763
                     /locus_tag="ACL3JB_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0686685.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            2842..>4478
                     /gene="pspC"
                     /locus_tag="ACL3JB_002035"
     CDS             2842..>4478
                     /gene="pspC"
                     /locus_tag="ACL3JB_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR0686686.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFLGGVVHAEGVRSEN
                     TPKVTSSGDEVDEYIKKMLSEIQLDKRKHTHNFALNLKLSRIKTEYLYKLKVNVLEEK
                     SKAELTSKTKKEVDAAFEKFKKDTLKLGEKVAEAQKKVEEAKKKAKDQKEEDHRNYPT
                     NTYKTLELEIAESDVKVKEAELELLKEEAKTRNEDTINQAKAKVKSEQAEATRLKKIK
                     TDREQAEATRLENIKTDREKAEEVKDKLKRRTKRAVPGEPATPDKKENDAKSSDSSVG
                     EETLPSPSLKSGKKVAEAQKKVAEAEKKAKDQKEEDRRNYPTNTYKTLDLEIAESDVK
                     VKEAELELVKEEAKESRNEEKVKQAKAKVESKKAEATRLENIKTDRKKAEEAKRRAAE
                     EDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPENPAEQPKAEKPADQQAEEDYA
                     RRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSW
                     YYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT         1608 a          673 c          953 g         1244 t
ORIGIN      
        1 agctgcaaga tgaatgattt tcttgtattg acgttgttgt tgacaaaaag tagcggataa
       61 atgaaatcca ttccattatc atagatgata ggctggtagg aaattttcaa atagcataca
      121 ggaaatagat gtatggagtt ctggtagtag aaagggagag agatgaacat tttagttgca
      181 gatgacgagg aaatgattag agaaggaatt gcagcatttc tgacagaaga gggttatcat
      241 gtcattatgg ctaaggatgg acaagaggtc ttggaaaaat ttcaagatct ccctatccat
      301 ctcatggtac tggatttaat gatgcctagg aagagtggtt ttgaagtgtt aaaagaaatc
      361 aatcaaaagc acgatattcc tgtcatcgtc ttgagtgctc tgggagatga aactactcag
      421 tcacaggtat ttgatctcta tgctgatgat catgtgacaa aacctttttc tttggtactg
      481 cttgtcaagc gtattaaggc gcttatcaga cgttactacg tcatagagga tctttggcga
      541 tatcaggatg taacagtgga ttttacctct tacaaagcac attataaaaa tgaagaaatt
      601 gatctcaaac caaaggaatt actggtacta aagtgtttga ttcagcataa aaatcaagtt
      661 ttaagtagag agcagatatt ggaagaaatt tcaaaagatg tagctgattt accttgtgat
      721 agggtcgttg atgtctatat tcgtactctt cgcaaaaaat tagctttaga ttgtatcgtg
      781 actgtgaaaa atgttgggta taagattagc ttatgataaa aaatcctaaa ttattaacca
      841 agtctttttt aagaagtttt gcaattctag gtggtgttgg tctagtcatt catatagcta
      901 tttatttgac ctttcctttt tattatattc aactggaggg ggaaaagttt aatgagagcg
      961 caagagtgtt tacggagtat ttaaagacta agacatctga tgaaattcca agcttactcc
     1021 agtcttattc aaagtccttg accatatctg ctcaccttaa aagagatatt gtagataagc
     1081 ggctccctct tgtgcatgac ttggatatta aagatggaaa gctatcaaat tatatcgtga
     1141 tgttagatat gtctgttagt acagcagatg gtaaacaggt aaccgtgcaa tttgttcacg
     1201 gggtggatgt ctacaaagaa gcaaagaata ttttgctttt gtatctccca tatacatttt
     1261 tggttacaat tgctttttcc tttgtttttt cttattttta tactaaacgc ttgctcaatc
     1321 ctctttttta catttcagaa gtgactagta aaatgcaaga tttggatgac aatattcgtt
     1381 ttgatgaaag taggaaagat gaagttggtg aagttggtga agttggaaaa cagattaatg
     1441 gtatgtatga gcacttgttg aaggttattc atgagttgga aagtcgtaat gagcaaattg
     1501 taaaattgca aaatcaaaag gtttcctttg tccgcggagc atcacatgag ttgaaaaccc
     1561 ctttagccag tcttagaatt atcctagaga atatgcagca taatattgga gattacaaag
     1621 atcatccaaa atatattgca aagagtataa ataagattga ccagatgagc cacttattgg
     1681 aagaagtact ggagtcttct aaattccaag agtggacaga gtgtcgtgag accttgactg
     1741 ttaagccagt tttagtagat attttatcac gttatcaaga attagctcat tcaataggtg
     1801 ttacaattga aaatcaattg acagatgcta ccagggtcgt catgagtctt agggcattgg
     1861 ataaggtttt gacaaacctg attagtaatg caattaaata ttcagataaa aatgggcgcg
     1921 taatcatatc cgagcaagat ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg
     1981 accaagaact agaacattta tttgatatat tctatcattc tcaaatcgtg acagataagg
     2041 atgaaagttc cggtttgggt ctttacattg tgaataatat tttagaaagc tatcaaatgg
     2101 actatagttt tctcccttat gaacacggta tggaatttaa gattagcttg tagacagatt
     2161 agttttttat taaagttcat atagggttaa cataagtgtg ttattctttg tgtagataaa
     2221 agaaaggata ctaatatggt attagcgatt attttagtaa cattccttat tcgattgatt
     2281 tttttaaagc gttcgataga gaatgagaaa cgaatcctta gcaatggcgg gaaagaattt
     2341 ggagttgaga atacaaaacg attaactatg gctcatattg ttttttatct ctcttgcttg
     2401 gttgaggcaa tggtgcacaa gacaattttt gatggcatgg gcatggttgg tttagtcttg
     2461 cttatttttt ctatgctgat gttgatgttg gtgattcact tgttgggaga tatttggaca
     2521 gtgaagctta tgcttgtcaa taatcacaaa tatgtagatc atatcttgtt taggacagta
     2581 aaacacccta attacttttt aaatatttta cctgagttga ttggcttgac cttgttgagt
     2641 catgcttatg tgacttttgt tttagttttt ccagtttatg cagttatttt gtatcgacga
     2701 atagctgaag aggaaaagct attacatgaa gttataatcc caaatggaag cataaagaga
     2761 taaatacaaa attcgattta tatacagttc atattgaagt gatatagtaa ggttaaagaa
     2821 aaaatataga aggaaataat tatgtttgca tcaaaaagcg aaagaaaagt acattattca
     2881 attcgtaaat ttagtattgg agtagctagt gtagctgttg ctagcttgtt cttaggagga
     2941 gtagtccatg cagaaggggt tagaagtgag aataccccca aggttacatc tagtggggat
     3001 gaagtcgatg aatatataaa aaaaatgttg agtgagatcc aattagataa aagaaaacat
     3061 acccacaatt tcgccttaaa cctaaagttg agcagaatta aaacggagta tttgtataaa
     3121 ttaaaagtta atgttttaga agaaaagtca aaagctgagt tgacgtcaaa aacaaaaaaa
     3181 gaggtagacg cagcttttga gaagtttaaa aaagatacat tgaaactagg agaaaaggta
     3241 gcagaagctc agaagaaggt tgaagaagct aagaaaaaag ccaaggatca aaaagaagaa
     3301 gatcaccgta actacccaac caatacttac aaaacgcttg aacttgaaat tgctgagtcc
     3361 gatgtgaaag ttaaagaagc ggagcttgaa ctattgaaag aggaagctaa aactcgaaac
     3421 gaggacacaa ttaaccaagc aaaagcgaaa gttaagagtg aacaagctga ggctacaagg
     3481 ttaaaaaaaa tcaagacaga tcgtgaacaa gctgaggcta caaggttaga aaacatcaag
     3541 acagatcgtg aaaaagcaga agaagttaaa gataaactaa agaggcggac aaaacgagca
     3601 gttcctggag agccagcaac acctgataaa aaagaaaatg atgcgaagtc ttcagattct
     3661 agcgtaggtg aagaaactct tccaagccca tccctgaaat caggaaaaaa ggtagcagaa
     3721 gctcagaaga aggtagcaga agctgagaaa aaagccaagg atcaaaaaga agaagatcgc
     3781 cgtaactacc caaccaatac ttacaaaacg cttgaccttg aaattgctga gtccgatgtg
     3841 aaagttaaag aagcggagct tgaactagta aaagaggaag ctaaggaatc tcgaaacgag
     3901 gaaaaagtta agcaagcaaa agcgaaagtt gagagtaaaa aagctgaggc tacaaggtta
     3961 gaaaacatca agacagatcg taaaaaagca gaagaagcta aacgaagagc agcagaagaa
     4021 gataaagtta aagaaaaacc agctgaacaa ccacaaccag cgccggctcc tcaaccagaa
     4081 aaaccaactg aagagcctga gaatccagct ccagctccaa aacctgagaa tccagctgaa
     4141 caaccaaaag cagaaaaacc agctgatcaa caagctgaag aagactatgc tcgtagatca
     4201 gaagaagaat ataatcgctt gactcaacag caaccgccaa aaactgaaaa accagcacaa
     4261 ccatctactc caaaaacagg ctggaaacaa gaaaacggta tgtggtactt ctacaatact
     4321 gatggttcaa tggcgacagg atggctccaa aacaatggct catggtacta cctaaacagc
     4381 aatggcgcta tggcgacagg atggctccaa aacaatggtt catggtacta tctaaacgct
     4441 aatggttcaa tggcaacagg atggctccaa tacaatgg
//
LOCUS       DBEJNA010000071         4171 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEJNA010000071 DBEJNA010000000
VERSION     DBEJNA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.71"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..164)
                     /locus_tag="ACL3JB_002036"
     CDS             complement(<1..164)
                     /locus_tag="ACL3JB_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR0686687.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADN"
     gene            complement(323..1930)
                     /locus_tag="ACL3JB_002037"
     CDS             complement(323..1930)
                     /locus_tag="ACL3JB_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0686688.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            2083..3567
                     /locus_tag="ACL3JB_002038"
     CDS             2083..3567
                     /locus_tag="ACL3JB_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0686689.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3662..4144
                     /locus_tag="ACL3JB_002039"
     CDS             3662..4144
                     /locus_tag="ACL3JB_002039"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0686690.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1216 a          954 c          798 g         1203 t
ORIGIN      
        1 atattatcag cgtaatagtc taatagatag ttaaatgtag ttggatttcc actaaaggtt
       61 gatgagtaag tttttgtatc tgaacctgat tggccgcaag cagctaaaag caaagcagat
      121 gcaaaagtca ggcctgcact aaggacacgc ttctttatgt tcatcttctt tctccttaat
      181 agtgggaatt tgtaaagtta attgaatttc aagaatgaaa gtttataaac tttggttata
      241 aaaaacaaag gatttctgtc ttttatacag tcctcccttg tttttatacg atttcaattt
      301 taaatttttc tgcaaaaaat atttatagta attccacaca gaaagcatcc catggagcca
      361 agacctgttt ttcaagtact tctttagccg cagtgttttc aatcaagaca gatttgactt
      421 ttccttctac tgtcaagtct tgctcttcat tggacaagtt agccacaact aggaagcgac
      481 ggtcgccatc cttacgtata taagcaaaga ccttatcagc cgtatcaagc aattcaaagt
      541 cagctcgaac tagccagcta ttctccttgc gaatttggac cagtttctga taggtataga
      601 aaatagaatc tggatttgcc agcgcttctt ggacattgat catctcgtaa tttggattaa
      661 ccgccaacca aggttgacct gttgagaaac cagcgttttt gctctcgtcc cattgcatag
      721 gggtacgggc attgtcacgt ccaataacac ggatactgtc catgatttct tcaatcggaa
      781 cacctttttc aagagcctca cgcgcatagt tgagagattc aatatcttct acttgatcca
      841 gtgtttcaaa cggatagttg gtcatcccaa tctcctcacc ttggtagata taaggagttc
      901 ctctcataag atgaagcaag attgcaaagg ctttggcaga tttttcgcgg tattcttggt
      961 catttcccca gattgagacg atacgaggga ggtcatgatt gttccagaag agggaattcc
     1021 aaccgtcctc aactcctaac tctgtctgcc atttgttgaa gatttctttt aacttagcga
     1081 tattcagctc tttttgatag tgccatttag gctgaccttc ctgatactga agaccgatat
     1141 gttcaaactg gaagaccata gacaattctt gcccctttgg atcagagtaa agcttggcaa
     1201 tctctggcgt tgctccccaa gtctccccta ctgtcaagag atccttatct ccaaaggtcg
     1261 cctgattcat ttccttgaga tagggatgga gcataggacc attattgact accttctcgt
     1321 caggaatttt gccaatcatg tcaataacat ccatacggaa accaccaata cctttatcaa
     1381 tccagaagtt catcatctca taaattttct ggcgaagttt ttcattttcc cagttgagat
     1441 ccggctgttt cttgctgaaa aagtggagat agtattgacc tgacttttca tcgtattccc
     1501 aagcagaccc actaaagata gaatctaggt cattgggttc atcgcgccag atatagtagt
     1561 ctcgctcagg gctgtcagta ttttcacagg cttcgacaaa ccaagcatgt tcatctgagg
     1621 tatgattaac caccaagtcc atgatgatac gaatgtcacg cttcttagct tctgcaatca
     1681 gctgatccat gtcctccatg gttccaaaaa tagccgcaat cgcttgataa tcagcaatat
     1741 catagccatt atcatccata gggctgtcat aaacgggaga aagccaaatt gctgtgattc
     1801 ctagcttggc tagatagtcc aacttactgg taatacctgg caaatcacca actccatctc
     1861 cattactatc cataaaactc tttggataga cttgatagac tacggcattg tgccaccatt
     1921 tttcttgcat ctgtttacct cattatttta ataatctata gtatatgata gcacttttta
     1981 aaattttgtg caagcgtttg cttaatcttt ttaatttatt ttttagctcc gtagtttcct
     2041 aacttccaat tttttattat aatagagtcc agaggtaaaa aaatgaaaaa acaagctttt
     2101 agttctgaac agtatttgaa tttacaacgc gaccatattt tggagcgcat taaccaattt
     2161 gacggcaagc tctacttaga gtttggcggt aaaatgttag aagatttcca cgctgctcgt
     2221 gtccttcctg gttatgaacc tgacaacaaa atcaagctct tgcaagaatt gaaagagcag
     2281 gttgaggttg tgattgccat taatgctagc aacattgaac attccaaagc acgtggcgac
     2341 ttgggcattt cttatgacca agaagttctt cgtttgattg acaaattcaa tgaattaggg
     2401 atttttgttg gttccgttgt cattacacaa tacgctggcc aacccgctgc agatgccttc
     2461 ctcaaccaac ttgagaaaaa cggaattgat tcttatcttc attatccaat caaaggatat
     2521 ccgacggata tggatcacat catttcccca gaaggcatgg gcaaaaacga ctacatcaaa
     2581 accagtcgca acttgattgt cgtaaccgct cctggacccg gttctggaaa attggcaacg
     2641 tgtatgtcca atatgtacca cgaccaaatc aatggcataa agtctggcta cgctaaattt
     2701 gaaaccttcc ctgtttggaa tcttcccctt catcatccag ttaacttggc ttatgaagct
     2761 gccacagctg accttgatga tgtcaacatg attgacccct tccatcttca aacctatgga
     2821 gaaaccactg tcaactacaa ccgtgatatc gaaatcttcc cagtgctcaa gcgcatgttg
     2881 gaacgtattc tcggaaaatc accatacgct tcaccgacag atatgggtgt caacatggtt
     2941 ggtttcgcta ttacagatga cgaggctgct gtcgaagctt ctaaacaaga aatcatccgc
     3001 cgttactatc aaacagttct tgacttcaaa gctgaaaaag ttggcgaagc tgccgtcaag
     3061 aaaattgagt tgctcatgaa cgacctcggt atcacacctg cagaccgtaa ggttgctgtc
     3121 gttgcgcgcc aaaaagcaga agaaactggt ggaccagccc tagcctttga attgccaaat
     3181 ggggaaatcg tcactggtaa gaactcagaa ctctttggcc ctacagccgc tgccttgatc
     3241 aacgccatca aaaaatcagc tgacatcgct aaagaagtaa aactaatcga gcctgaagtt
     3301 gttaagccaa tccaaggtct taaaatcgat catctcggta gccgcaatcc acgccttcat
     3361 tcaaatgaaa tcctgattgc acttgctatc acagctacag aaaatcctga tgctgcccgc
     3421 gctatggaag aactcggcaa cctcaaagga agcgaagccc actcaaccat catcttgact
     3481 gatgaagaca agaatgtcct tcgtaaactg ggtatcaacg taacctttga cccatactac
     3541 caatacgacc gcttatatcg taagtaaaga tttcaacctc tctagcctcg gagaggtttt
     3601 ctctctgtct caggaacaac ctttatgata taatgagaga agaaaactga aaggatttac
     3661 catgtcaaaa gaagttattg tcgaaagttt tgaacttgac cacaccattg tcaaagcacc
     3721 ctatgttcgc ttgattgggg aagaaacagg accaaaagga gacatcatct ccaattatga
     3781 tattcgcttg gtgcaaccaa acgaagactc tatccctact gccggccttc acactatcga
     3841 gcacctctta gccaaactca tccgtacccg cattgacggc atgattgact gttcaccatt
     3901 tggttgccgc acaggcttcc acatgattat gtggggacgt cacaccagtg ctaaaatcgc
     3961 agctgttatc aaggattcgc tcaaggaaat cgctgaaact actacttggg aagatgtccc
     4021 agggacaacc atcgaatctt gcggaaacta caaggaccac agcctcttct ctgctaaaga
     4081 atgggcaaaa ctcatcttgg aacaagggat ttcagatgat gcctttgaac gtcatgtgat
     4141 ttaaaatcga gtaggggata atctctagcc c
//
LOCUS       DBEJNA010000072         3463 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEJNA010000072 DBEJNA010000000
VERSION     DBEJNA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.72"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..174
                     /locus_tag="ACL3JB_002040"
     CDS             <1..174
                     /locus_tag="ACL3JB_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HGR0686691.1"
                     /translation="WVKDGDTWYYLEASGAMKASQWFKASDKWYYVNGSGALAVNTTV
                     DGYGVNANGEWVN"
     gene            complement(377..1642)
                     /locus_tag="ACL3JB_002041"
     CDS             complement(377..1642)
                     /locus_tag="ACL3JB_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0686692.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKIAVAETSLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSRLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIIQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRIHLTNKEILNKLLSYSEDLKHHYQLYQLYQLLLFHFQNKEPEKF
                     FGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFG
                     FRNFENFKKRIFIALNIKKERTNFVLSRA"
     gene            1845..>3463
                     /gene="pspC"
                     /locus_tag="ACL3JB_002042"
     CDS             1845..>3463
                     /gene="pspC"
                     /locus_tag="ACL3JB_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HGR0686693.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLVMGSVVHATENEGTT
                     QAPTSSNRGNESQAEQRRELDLERDKVKKEVREYKEKKVKELYSKSTKSRHKKTVDIV
                     NKLQNINNEYLNKIIQSTSTYEELQKLMMESQSEVDKAVSEFEKDLSSSSSSGSSTEP
                     EASDTAKPNKPTELEKKVAEAQQKVEEAEKKAKDQKEEDHRNYPTITYKTLELEIAEF
                     DVKVKEAELELLKVKAKESRDEKKIKQAEAEVESKQAEATRLKKIKTDRKKAEEEAKL
                     KEAVEKNAATSEQGKPKRRVKRGALGEQATPDKKDYFEKDFRPAFNKNQQMVAIQESL
                     NKLDDETKTVPDGAKLTGEAGNAYNEVRDYAIKVVSENKKLLSQTAVTMDELAMQLTK
                     LNDAMSKLKEAKAKLVPEVKPQPENPEHQKPTTPAPDTKPIPQPEGKKPSVPDINQEK
                     EKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDEFKKQALSEIDNVNTKVEI
                     ENTVHKIFADMDAVVTKFKKGLTQDTPKEPD"
BASE COUNT         1240 a          572 c          726 g          925 t
ORIGIN      
        1 tgggtgaaag atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc
       61 caatggttca aagcatcaga taaatggtac tatgtcaatg gctcaggtgc ccttgcagtc
      121 aacacaactg tagatggcta tggagtcaat gccaatggtg aatgggtaaa ctaaacctaa
      181 tataactagt taatactgac ttcctgtaag aactctttaa agtattccct acaaatacca
      241 tatcctttca gtagataata tacccttgta ggaagtttag attaaaaaat aactctgtaa
      301 tctctagccg gatttatagc gctagagact acggagtttt tttggctctt tgtcaactgt
      361 agtgggttga agtcagctaa gctcgagaaa ggacaaaatt tgtcctttct tttttgatat
      421 tcaaagcgat aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc
      481 gcttgataag tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt
      541 gaagggcgtt gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa
      601 taggatgaac ctgcttaaga ttgtcctcaa taagcccgaa aaatttctct ggttccttat
      661 tctggaagtg aaaaagcaag agctgataga gctgatagag ctgatagtgg tgtttcaagt
      721 cttccgaata actcaaaagc ttgtttaaaa tctctttatt ggttaaatgt atacgaaaag
      781 taggacgata aaatcgctta tcactcagtt tacggctatc ctgttgaatg agtttccagt
      841 agcgcttgat agccttgtat tcatgagact ttcgatccaa ttgattcatg atttgaacac
      901 gcacacgact catggcacgg ctgagatgtt ggataatatg gaaacgatct agaacgattt
      961 tagcacacgg gaaaagctgt ctagctaagt catagtaagg gctaaacata tccatagtaa
     1021 taattttgac gcgacatcgg acaactctat cgtagcgaag aaagtgattt cgaatgatag
     1081 cttgtgttct tccctcaaga acagtgatga tattgagatt gttaaaatct tgcgcaatga
     1141 agctcatctt tccctttgta aaagcatact catcccaaga cataatctca ggaagacgcg
     1201 aaaaatcatg tttaaagtga aaatcattga gcttacgaat aacagttgaa gttgagatgg
     1261 aaagctgatg ggcaatatca gtcatagaaa tcttttcaat caacttttga gcaatctttt
     1321 ggttgatgat acgagggatt tggtgatttt tcttgacgag ggaagtctca gcgaccgcta
     1381 tttttgagca ctgatagcac ttgaatcgac gctttctaag gagaattcta gtaggcatac
     1441 cagtcgtttc aagataagga attttagaag gtttttgaaa gtcatatttc ttcatttgac
     1501 ttccgcactc agggcaagat ggggcgtcgt agtccagttt ggcgatgatt tccttgtgtg
     1561 tatctttatt gatgatgtct aaaatctgga tattagggtc tttaatgtct agtaattttg
     1621 tgataaaatg taattgttcc atatgattct ttctaatgag ttgttttgtc gcttttcatt
     1681 ataggtcata tgggactttt tttctacaca aaataggctc cataatatcc ataggggatt
     1741 tacccactac aaatattata gagccaaata atgtagcaaa tttcatatac aattcatatt
     1801 agcaggatat actgtagtta attaaaatta tggagaatat agacatgttt aaatcaaatc
     1861 atgagcgaag aatgcgttat tccattcgta aatttagtgt aggagtagct agtgtagctg
     1921 ttgccagtct tgttatggga agtgtggttc atgcgacaga gaacgaggga actacccaag
     1981 cacccacttc ttctaatagg ggaaatgaaa gtcaggcaga acaacgtaga gaactcgatt
     2041 tagaacgaga taaggtaaag aaagaggtca gggaatataa agaaaaaaaa gtgaaagagc
     2101 tctattcaaa atcaactaaa agtcgacata agaagactgt agatatagtt aacaagttgc
     2161 aaaacattaa taacgagtat ttgaataaaa taattcaatc aacctcaaca tacgaagaac
     2221 tacagaaact gatgatggag agtcaatcag aagtagataa agctgtgtct gaatttgaaa
     2281 aggacttatc ttcttcgtca agttcaggct cttccacgga accggaagct tcagatacag
     2341 cgaagccaaa caagccgaca gaactagaaa aaaaggtagc agaagctcag cagaaggttg
     2401 aagaagctga gaaaaaagcc aaggatcaaa aagaagaaga tcaccgtaac tacccaacca
     2461 ttacttacaa aacgcttgaa cttgaaattg ctgagttcga tgtgaaagtt aaagaagcgg
     2521 agcttgaact attaaaagtg aaagctaagg aatctcgaga cgagaaaaaa attaagcaag
     2581 cagaagcgga agttgagagt aaacaagctg aggctacaag gttaaaaaaa atcaagacag
     2641 atcgtaaaaa agcagaagaa gaagctaagt tgaaggaagc tgttgaaaag aatgcagcga
     2701 cttcagagca aggtaaacca aagaggcggg taaaacgagg agctcttgga gagcaagcaa
     2761 cacctgataa aaaagattat tttgaaaaag acttccgtcc agctttcaat aaaaaccagc
     2821 agatggtagc cattcaagaa tccttgaaca aactagatga tgaaacaaaa actgttccag
     2881 atggggctaa actcacagga gaagctggaa atgcctataa tgaggtcaga gattatgcaa
     2941 taaaagttgt ttctgaaaac aagaaacttc tatcacagac agcagtgaca atggatgaac
     3001 tggcaatgca attaaccaaa ttgaacgatg ccatgtctaa attgaaagaa gctaaagcga
     3061 aattggtacc agaggttaaa ccgcagccgg aaaatccaga gcatcaaaaa ccaacaactc
     3121 cagctccgga taccaaacca atccctcaac cagagggtaa gaaaccaagc gtaccagata
     3181 ttaatcagga aaaagaaaaa gctaagcttg ctgtagcaac ctacatgagc aagattttag
     3241 atgatataca aaaacatcat ctgcagaaag aaaaacatcg tcagattgtt gctcttatta
     3301 aggagcttga tgagtttaaa aagcaagctc tttctgaaat tgataatgta aataccaaag
     3361 tagaaattga aaatacagtc cacaagatat ttgcagacat ggatgcagtt gtgactaaat
     3421 tcaaaaaagg cttaactcag gacacaccaa aagaaccaga taa
//
LOCUS       DBEJNA010000073         3173 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEJNA010000073 DBEJNA010000000
VERSION     DBEJNA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.73"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            24..218
                     /locus_tag="ACL3JB_002043"
     CDS             24..218
                     /locus_tag="ACL3JB_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0686694.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(324..493)
                     /locus_tag="ACL3JB_002044"
                     /pseudo
     CDS             complement(324..493)
                     /locus_tag="ACL3JB_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(571..1881)
                     /locus_tag="ACL3JB_002045"
     CDS             complement(571..1881)
                     /locus_tag="ACL3JB_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0686695.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2118..2990
                     /gene="nadC"
                     /locus_tag="ACL3JB_002046"
     CDS             2118..2990
                     /gene="nadC"
                     /locus_tag="ACL3JB_002046"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0686696.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          979 a          526 c          722 g          946 t
ORIGIN      
        1 atttttcatt acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt
       61 ttgctattag ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc
      121 atcgtatatt gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta
      181 ctggtaaaaa tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac
      241 acctctactt ctaaaatatt gttagaaatc gatttgactg tcctgttctt atttcatttt
      301 actacatctt aaattgagta tgaagaaagt gcgctcccat gtcctgggaa cgcactttct
      361 tcatattttt catattcttg aatccatcga taaagactat tgggatgaat ttttaaagtt
      421 gaactaatca tttttacagg atgaggttta cagcagagag tttgaaggct ttatcaaagg
      481 tttttcttgg cataatgact tttcctcgtt tccacttaat tttgtgtcta ctttattata
      541 ccaagtccac ccttaagtta gataataaat ctaacttaag gaagctaaaa ggatgagaat
      601 ccaggtggtc aagagtccca aacttaagct gatggggaca cccagaataa tttgcttttt
      661 gaaggcaagg ccgcgttcct ctatattggg aagtgagagt tgaatgagag aaccagctga
      721 tgaaaagggt gagatattag tagatagagc gccaataacg gtggctgttg tgagtaagtg
      781 aatatcaatc tgaggatttt gagcactgat gatagcaatg atgggaaaga gggctggagc
      841 tacaacggat agggtggaac taaagagtga catcactccg gctatcacac aaaagaacag
      901 aggtaaccag aaatgaggaa tggttgttgt catgaggtgc cctatcagtg tgactaaacc
      961 tgacttgacc gctagagaca ttagtaagct catgccgcag agcatgataa ttgtagccca
     1021 gggaacctta gctaaaatgg cttcttgctt ccctaatttg agccttaagg cgaggcagac
     1081 catgagtatt gagacaaagc caatatcaaa tgttttttga taagtagcta tccaggcgat
     1141 gtttgggaaa atgagatgca acaagggaaa aagccaaacc aaaaccatgc tgctgatcat
     1201 gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt ggttggtcaa tagtcaagga
     1261 tgagtttgtt cttcccttac tatagtgact gtaacaggat aataaaagca agacgatgag
     1321 tgggtagata atgctgacga taaagatatg attgccaagt gaaaaagctt gctcttccca
     1381 tcccatttgc ttaaacaggc cttgaaagac aatgcctgag ctactggtta tcaaattagc
     1441 ccctcctgaa gctccccaat tgacggcttg agctccaatc aaagggtgtt tgtccgcttt
     1501 ttgacagagg gtaatcgcta gaggacagca aacggccata gtagtgaaaa atccagcacc
     1561 taaagcagac aaaagggttg ccatcaggta taaaatcatg tagagggcgt tagggtgggt
     1621 gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga gtaccgttag ttgttgcaac
     1681 gttataaaag agagagacgc taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag
     1741 aagttctttg gggcttaatc ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc
     1801 cagcaggcca atattgattt tggtgcggta accaattcca atggctagag caatggcgct
     1861 aatcattatt aaatgaatca ttgaattgtc ctttcagtta gaatatggaa ataggttggc
     1921 aattttggcg ctcaaaagac cacctgtttc ctattggtac ttgactatta tacacaaaaa
     1981 aaatacaatt gtcttgacaa ttgtattgac acttgttaga attaaaaatg aggtattcag
     2041 gcttgtgatt tcctatggaa gttaatagtg attgcctcta atgcttacaa gtgatattaa
     2101 aaatagagga cctagtgatg tcaatcattt caactgattt aacccctttt caaatagatg
     2161 atacattgaa agcagccttg cgagaagatg ttcattccga agattacagt accaatgcca
     2221 tttttgatca tcatggccaa gccaaggtgt cgctttttgc caaggaagct ggtgttttag
     2281 cggggctaac cgtttttcaa agggttttta ccctatttga tgccgaggtg accttccaga
     2341 atcctcatca atttaaggat ggggatcgtt tgactagtgg cgatttggtt ttagaaatca
     2401 taggctcggt gagaagtctc ttaacatgtg aacgcgttgc cttgaatttt ttacaacatt
     2461 tatcagggat tgcttcgatg acagctgctt atgtagaagc cttaggcgat gattgcatta
     2521 aggtatttga tactcgaaaa actactccta atttacgtct ttttgagaaa tatgccgtga
     2581 gagttggcgg tggctataat catcgcttta atttatcaga tgctatcctg ctaaaagaca
     2641 atcacattgc ggcagtaggt agtgttcaaa aggcaattgc tcaagcgcgt gcctatgccc
     2701 cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc tgctgccgaa gaagctgcgg
     2761 cggcgggtgc tgatattatc atgttggata atatgtcatt ggaacagatt gaacaggcca
     2821 ttaccctaat tgcaggacgt tctcggattg aatgttctgg aaatattgat atgaccacta
     2881 ttagccgttt tcgtggttta gcgattgatt acgtctccag tggtagttta acccatagtg
     2941 ctaagagtct tgatttttcc atgaaggggt taacctacct tgatgtctaa gttgtaaaat
     3001 aaactaactt tttaaaggat gtctttcctc tagaacgagt tttatgtcag atagtttaaa
     3061 cgcctcttca aatatagtaa aatgaaccaa aaatagtaca caatgtggta taatcttttt
     3121 atggcatatt caatagattt tcgtaaaaaa gttctctctt attgtgagcg aac
//
LOCUS       DBEJNA010000074         2262 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEJNA010000074 DBEJNA010000000
VERSION     DBEJNA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.74"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..190
                     /locus_tag="ACL3JB_002047"
     CDS             <1..190
                     /locus_tag="ACL3JB_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686697.1"
                     /translation="TRYPNPQKRLEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQIE
                     IRNSLDKTIDFSYSLSFS"
     gene            complement(156..1631)
                     /locus_tag="ACL3JB_002048"
     CDS             complement(156..1631)
                     /locus_tag="ACL3JB_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0686698.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          670 a          497 c          415 g          680 t
ORIGIN      
        1 gacacgctac cctaatcctc agaaaaggct tgaggcagga tttgataagc tgatagaaat
       61 taagcgattg accgcttcta attcaagggc tttttgccgt gctctaaaat catcgccaaa
      121 tcatcaaatt gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc
      181 tttctcttaa taacgttgat atgattgacc tctggatctt ccgtcccttg gagggagcaa
      241 ccacgttcct tggcgaattg gatatagtcg acaatttctc gtgtaatgcg ttcaccagga
      301 gccaagatag gaatacctgg agggtaacac ataacaaatt ctccacagac ctgtccaaca
      361 gaatcatcca aagttaaact ttttctttct gaatagaagg cttcttgcgg agacagcact
      421 aactcgggct gaatatattc tcctgctatc aaatcttttc catctcttga atagagtctc
      481 ttaatatcag ccagagcacc aaccaagcgc tcgatgtctt ggatgcggtc gccgatggaa
      541 atataggcca agatattgcc gatatcacca aactcgatct gaatgtcgta ttcgtctcgc
      601 aagaggtcat aaacctcgat acctgttaag ccaataccct gagtgtaaac tgacagctta
      661 gttacgtcaa aatcgcaaac cgaaacaccg tctattaact cttttgagta ggcatagtag
      721 ccaccgatag cattgatttc acggcgggca tactcagata gctcaatgac tttctcaaac
      781 gactctttac cacgaagggc caagttgcga cgtgaaatat ccaaactagc catcaacaag
      841 taagaggcag atgtagactg ggtcaggtta attatctgac gaacgtattc agaattcatc
      901 tgctccccga taagtaaaat ggagctttgg gtcaaactcc caccagactt atgcatggaa
      961 actgctgcca tatcagcccc tgcatccata gcagaaattg gaagtttatc agtgaaatgc
     1021 aaatgcgctc cgtgggcttc atctactaaa accatcatgc cagcttcatg agccatttct
     1081 gtcaacccct ttaggtctga acagatgccg tagtaagtag gattgttgat taggatagcc
     1141 ttagcatctg gatggtcctt tatggcctgt gctactcggt cattttcaag acctaaagcg
     1201 ataccaatct taggatctac actcatctcg atatagatgg gaatggcacc acatagaacc
     1261 aacgcattga tagcagattt atggacattt cgtggcagaa taatcttatc tcctgccttg
     1321 caggttgcca gaatcatagt ctgcaccgat gaagttgttc caccaatcat tagaaaggca
     1381 tggctagctc caaaagcatc tgcagccagc tcctctgcat cacgaataat cgaaatagga
     1441 tggcctaaat tatccaaggg tttcatcgaa ttgacatcaa tgcctacaca tttttctcct
     1501 aagagttcga caagttctgg atttccccgt ccacgcttgt gacctggaac atcaaaggga
     1561 acaatccttt tcttgcgtaa cttcaccaag gcctcataaa ttggggcttg gttttgatct
     1621 aactctttca aaacatactc ctttcaatat ttttaggacc ttatgaaaac taaggaacta
     1681 aaggttgact catgaaaaaa gagcaggttt tcacctgctc tgcaatcttc tgacgtgttt
     1741 attttggttt ctgttgagta tgtctgttcc cgatgtttcc taactctcta gtagcaaata
     1801 ttacgtactt tattgatcgt ttcacaagat gacgtgtgct ttcaccacac taaaaattta
     1861 tgaattagaa caagtgtcct aacatcaact tataaaagta ggcttttaac cctatcaata
     1921 atgtggcttt tcaaccacgc ttcggcattc aaccctgcct gtccgtaggc attttttact
     1981 cgggtttata tttgctagaa aacatcatct cattttctaa gctttattac tatatcatgt
     2041 ttttaagaac ttgtaaagta ttttttgata aaaaataaaa atatagtaga ttgaaactag
     2101 aatagtacac ctctgcttct aaaacattgt tagaaataga ttttactgtc ctgatcgatt
     2161 tgttctgttc ttgtttcatt ttactatatg ttcgtaaatg aaagttctat aatgaagtta
     2221 gccacccagc cctcctaaaa attagatggt tcaactaacc ga
//
LOCUS       DBEJNA010000075         1878 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEJNA010000075 DBEJNA010000000
VERSION     DBEJNA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.75"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..1754)
                     /locus_tag="ACL3JB_002049"
     CDS             complement(<1..1754)
                     /locus_tag="ACL3JB_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_142291904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HGR0686699.1"
                     /translation="MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRG
                     GVDTTQVMTETVEDKVSHSITGLDILKGIVAAGAVISGTVATQTKVFTNESAVLEKTV
                     EKTDALATNDTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESA
                     STSASISISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRK
                     RSVDSIEQLLASIKAAVFSGNTTVNGAPAINASLNIAKSETKVYTGKGVDSVYHVPIY
                     YELTVINDGSKLTFTYTVTYVNPTTKTLGNISNMSNGYSIYNSGTSIQTMLTLGSDLG
                     IPSGVKNSITDKNGRQVRSYNTSTMTTQGSGYTWGNGAQMNGFFAKQGYGLTSSWTVP
                     INGTDTSFTFTPYAARTDRIGINYFNGGGKVVESSTTSQSLSQSKSLSVSASQSASAS
                     ASTSASASASTSASASASTSASESASTSASASASTSASASASTSASSSASTSASASAS
                     TSASASASTSASSSASTSASASASTSASVSASTSASASASTSASVSASTSASASASTS
                     ASESASTSASASASTSAS"
BASE COUNT          501 a          399 c          413 g          565 t
ORIGIN      
        1 tcagatgctg aggtacttgc tgaagctgag gcactggttg atgcggattc agacgcgctg
       61 gtgcttgctg aggccgacgc actggtgctt gctgagactg atgcactcgt tgatgctgaa
      121 gccgaggcgc tggtgcttgc tgagactgat gcactcgttg atgctgaagc cgaggcgctg
      181 gtgcttgctg aagacgacgc actggtactt gctgaagctg acgcactggt tgacgctgaa
      241 gctgaggcac tggttgatgc tgaagacgac gcactcgttg atgctgaagc cgacgcactc
      301 gttgatgctg aggctgaggc agacgttgat gcggattcag acgcacttgt tgatgctgaa
      361 gctgaggcac tcgttgatgc tgaagccgac gcacttgttg atgctgaagc tgaggcgctt
      421 tgactagcac ttactgagag tgacttagac tgtgaaagtg actgactggt cgtgctagat
      481 tcaactacct ttcctccacc attgaagtag ttaattccaa ttctatctgt tctagcagcg
      541 taaggggtaa atgtaaagga tgtatccgtt ccattaattg gtacagtcca agatgatgtt
      601 aatccatatc cttgcttagc aaagaaacca ttcatttggg caccatttcc ccaagtatac
      661 ccactaccct gcgtcgtcat tgtagatgta ttataggatc gaacctgtct accatttttg
      721 tcagtaatgg agttctttac acctgaaggg ataccaagat cactgccaag ggttaacatt
      781 gtttgtattg aagtacctga attatagata gaatatccat tactcatatt tgatatatta
      841 ccaagagtct ttgttgtagg attcacatac gtaaccgtat aggtaaaggt caattttgaa
      901 ccatcattta tcactgtcaa ttcatagtaa attggaacat gatataccga atctacacct
      961 ttacctgtat aaacttttgt ctcactttta gcaatgttta gacttgcatt aattgcaggg
     1021 gcgccattta cagtcgtatt gccagaaaaa acagcagctt ttatagaagc cagcaattgc
     1081 tcgatggaat ccactgaacg cttgcgtcgc ttagcataag attggagatt gacatttgta
     1141 actgatgcta cataatcact agctggtttc ttacgatctt cttcgacctt cttagcagtt
     1201 gcttctgtag cggcagctgt ttgtgatcct accacagtag atgatgcaga gatacttatc
     1261 gaagccgatg tacttgctga ttctgatgca cttgtactcg ctgaggtcga agcgctggtt
     1321 gaggctgact cagatgcaga tgtacttgcc gactctgaag ctgacaaact agttgaactc
     1381 gctgaattac ttgtagatat cgtacctaga actactgtat catttgttgc caaagcatcc
     1441 gttttctcta cagttttttc aagtactgcc gactcatttg taaatacctt cgtttgagtt
     1501 gcaacggttc cacttatgac agctcccgca gcaactatcc ccttgaggat atcaagccca
     1561 gtaattgaat gacttacttt atcttctacc gtttcggtca tgacctgagt agtatcaaca
     1621 ccaccacgca tgaccttaaa caagccaaaa agagaagtcg aggcccgtag ccaatgcttc
     1681 cctgatttga ttaatttgaa ccgagttact cggtctgttt ctctatattc acccttctga
     1741 cgtctaaaaa atattttgaa atttcctttc gagtattatt ttcatgtatg gatataaata
     1801 aattaccata ctataattat agaataggga acccaaaata gcaagaaact tgaggtattt
     1861 ttgctaaaaa aaaagcat
//
LOCUS       DBEJNA010000076         1851 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEJNA010000076 DBEJNA010000000
VERSION     DBEJNA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.76"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..959)
                     /gene="xerA"
                     /locus_tag="ACL3JB_002050"
     CDS             complement(<1..959)
                     /gene="xerA"
                     /locus_tag="ACL3JB_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR0686700.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKF"
     gene            complement(1077..1490)
                     /locus_tag="ACL3JB_002051"
     CDS             complement(1077..1490)
                     /locus_tag="ACL3JB_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR0686701.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1487..1723)
                     /locus_tag="ACL3JB_002052"
     CDS             complement(1487..1723)
                     /locus_tag="ACL3JB_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR0686702.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          538 a          363 c          274 g          676 t
ORIGIN      
        1 atgaattttt ggtgtgaatg cttgacatta ttttgattga ccatggcata ggccagggtt
       61 gtgtcaatct tgctatgacc tagcagtttt tggacttgtt cgataggcat acctttatca
      121 attgccttag tcgctaaagt tcttctgaac ttatgtgggt gaaccttttg tatgccgagt
      181 ttgtctccta actttcttaa gcgaatctct acaccagcaa ttccaagtct ctgggctttt
      241 ccaactagcg ttacaaaaag agcagggtga ctatcttttc tgtcgttaag ataatttctt
      301 aaatgaattt tcgtccgagc gtcaaaatat actggtctct ccttctttcc tttaccaaag
      361 acaacacact ctctgttttc aaaatcaata tctgaacgat tcaactgtac aagctcccct
      421 acacgcatac ctgtcgatgc tagtaggtct attattgcca aatctctcaa attttcacag
      481 ttatcacgca taatttccaa atgttcatca gtataagttt ccttcacatt ttgctcagtc
      541 ttaattttct ttatccgtcg aatgggattt ttaatgatat attcctcttg ctcaagccaa
      601 gcaaaaaaag aagacaatat acgcctaata ttgtctaaat ttgccttact acaatccttt
      661 tcagactggt aatttgctaa ataactcctt aaatcatctg ttgtgagttg tgtcacagac
      721 tctttaatag cattaaacaa gttttcaatc gtcctctggt aataacgaat tgtttttgag
      781 ctacagccct ctacctgctt ggcggtaata aatagttgca acaggttatt attcgaatac
      841 ttctgctgct tttttccgtc tactagatga tgttctaaac tctctctcaa cgctagtaat
      901 tgttcattat ttaaaagagg taacatttct tgcatgataa ttgtaacttt tgattccata
      961 atttctcact ttcttattca tcaataaaaa gagacaatat cagtttctgc attacagaat
     1021 tctaatattg tctgttcatt tattttcttg tgctcattca aatccagcat actaggttac
     1081 tttttgacct tttctctaac agaatgttca gaaacccatt tggagtagct tgtcattttt
     1141 tcatcagtta aagcttctac tgcgatggtt acacacattt ttactgcttc ttctaccgtt
     1201 acagaaaaac gatagccgtt taattgtaaa aatttgacca aaacgaagaa agcagttctt
     1261 ttattagcat tagcaaaaac atgcttcttt atcaattgga caaatagtat cgttgcttta
     1321 tcaaaaattg ttggataaag agacttccca aagacaaatt gttctggtaa gttcacaatc
     1381 atatttaagg cagaagaact aactgtttga attttctcat ttggagaata ccgttgaatt
     1441 gctaaagcat ttattttttc aatttgcttt tctgtcagat agattgtcat ttttccacca
     1501 aagctttgaa aacatcgtcg tattcgtcaa atattttatc taaatttaag tcaaaggcat
     1561 catcagatac ataagaaacc tgctgcccca attcttcagg agtaaagata atctcaccac
     1621 ttggtaacaa tttcgcttcg tatttaacac cacttggaat attaaattca cttggaatcg
     1681 taatggtgat tgaatttcct tgttttcttg tttttactac catctgattt cctcctttga
     1741 agtattataa caaatcatta ccgtaattac aatggcagaa tatcagccaa aatactcctg
     1801 catcagagat ttcttcaaag tttcaagttc ttccagagat ttttggattg c
//
LOCUS       DBEJNA010000077         1704 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEJNA010000077 DBEJNA010000000
VERSION     DBEJNA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.77"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            130..562
                     /locus_tag="ACL3JB_002053"
                     /pseudo
     CDS             130..562
                     /locus_tag="ACL3JB_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            751..1050
                     /locus_tag="ACL3JB_002054"
     CDS             751..1050
                     /locus_tag="ACL3JB_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0686703.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1311..1634
                     /gene="tnpB"
                     /locus_tag="ACL3JB_002055"
     CDS             1311..1634
                     /gene="tnpB"
                     /locus_tag="ACL3JB_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0686704.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          584 a          336 c          295 g          489 t
ORIGIN      
        1 gttcgctcac aataagagag aactttttta cgaaaatcta ttgaatatgc cataagaaga
       61 ttataccaca ttgtgtacta tttttggttc atttcactat aataataacg atactagata
      121 atgaggaaaa tgcaatggca aacccaactt tcggagaaaa aaagcgaata cagactatat
      181 tgctcgctat ggcgtatatg cagttatccc taatcctgaa caaaaacaaa ttgttcttgt
      241 tcaagaacca aatggtgctt ggttcctacc atgtggagaa attgaagcag gtgaaaatca
      301 tcaggaagcc ctaaagcgtg agttgattga agagcttggt ttcacagcag aaattggtac
      361 ctattacgga caagctgacg aatatttcta ttctcgtcat cgtgatacct actactacaa
      421 tcctgcctac ctctatgaag caactccttt caaagaagta caaaagccac tagaaaactt
      481 taatcatatt gcctggttcc ctattgacga ggctatcaaa aaccttaaac gtggtagcca
      541 taaatgggcc attgaatctt gaaaaaaaca gcataagatt gactaatact cttcgaaaat
      601 aaaattcaaa ccacatcagc gtcgccttac catactcaag tatagcctgc ggctagcttc
      661 ctagtttgct cttttatttt cattgagtat aaatcaagcg actttattca aaaagtgcta
      721 taatagaatt agaaaatcgg aggaaatatt atgaagctta tcaatacgac aaactcacac
      781 tcgcaacttg taaaaagtca gctagaaagt accgatgcaa cccttgttga ggtttattct
      841 gcagggaata cagatgttat ttttacccaa gctccgcttc actatgaaat cctcatctca
      901 aacaaacacc gtgctattcg tgagcctgaa atcgaaacca ttcaagaatt tttcttgaaa
      961 cgtaaaattg ataaggcctc tgttgatgaa gccaatatca agacactcta ctcagagaaa
     1021 ttaattggaa tttcaatccc aatcaagtaa gaaaattgag taaaaactcg atttgagaga
     1081 aagtccaata agtctttcca taataaaacg catagtagca agagtttcta cacccactat
     1141 tatacgtttt tatcattttg aaatctgctg ctaatcaatg aagaagcaaa gatcaaacta
     1201 ggcagctagt tacaagttac gtaagcgcgt cataacaagg tatctatcct aattccccaa
     1261 cttccagtat actagataaa aaataattat cggaggaaaa gtattgtact atgatgattc
     1321 aactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg atacaaggaa
     1381 tcgattcact ggcttatctc gttaaaaccc actttgaatt ggatcctttc tccggtcaag
     1441 tctttctctt ttgtggtgga cgtaaagacc gctttaaagc cctttactgg gatggtcaag
     1501 gattttggat actatataaa cgctttgaga acggaaaact gacttggccc agtacagaaa
     1561 aggatgtcaa agctctcgca cctgaacaag tagactggct tatgaagggc ttttctatca
     1621 ctccccaaat atagtggatt taaactagaa tagtacaccc ctacttctaa aacattgtta
     1681 gaaatcgatt tgactgtcct gatc
//
LOCUS       DBEJNA010000078         1583 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEJNA010000078 DBEJNA010000000
VERSION     DBEJNA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.78"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(67..675)
                     /locus_tag="ACL3JB_002056"
     CDS             complement(67..675)
                     /locus_tag="ACL3JB_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGR0686705.1"
                     /translation="MQIKFIDKVSNFIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            886..951
                     /locus_tag="ACL3JB_002057"
                     /pseudo
     CDS             886..951
                     /locus_tag="ACL3JB_002057"
                     /inference="COORDINATES: protein motif:HMM:NF013577.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1000..>1583
                     /locus_tag="ACL3JB_002058"
     CDS             1000..>1583
                     /locus_tag="ACL3JB_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0686706.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIA"
BASE COUNT          627 a          162 c          263 g          531 t
ORIGIN      
        1 ttattttatc gttgaaatta gttaaaaatt tttataaaat caagatgcaa ggctatgaga
       61 tgttctctag tttaattttt catacttcga gaatataaag ttatataaaa atgcattagc
      121 atattttgtt attgagggaa gtataaaaat cattaaagtt atccaaacta gtaattgatt
      181 ctgtaatata aagaagagta gaactgggat aatttcaata attctaataa gaacggcaat
      241 aaaaaaatgt ttataggcta acatgattga attgtgtaga gaatttttta aagtgttatt
      301 atatctaccg attaaaggaa ttagaaatgt tgttgctatt aaatgaagta tgatatatat
      361 tactccaata tgtcgtaaga tagaaatgat atatataggt aatggtatgt agggtaggaa
      421 gaacaaactg aataataaga ttaaaattgg taaattagat attaatgctg ctcctaaatt
      481 tttccaataa tctttaaaaa aactgtttgc gaagtctcta tagggatagg attcctcgtg
      541 tcgtacaatt tttattagag ttgctattag ggcactttca cctgatccga tagcaataac
      601 tgttactact gacgctacat agagtagatt taacattata aaatttgaaa ctttatcaat
      661 aaattttatc tgcatcttta actcctgctg tttttatact tataatatca catcatttga
      721 gtttcatcaa ctttgaatac attaagaaag aatataacta tgaggaaagg aaaaaattat
      781 tatgaataaa tccaaaaaat ataaagaaag aattcattat gaatacgata atcttactaa
      841 atcagagaaa aaattgctga ctatatttta gttagagata gtgaaatagt ttatgaaacg
      901 tcttcagaaa ttgttagtaa agtaaaagtt ggagagggaa ctcttaatcg attttgcaaa
      961 aagattggat actctggttt tcaggaacta aaattaaaaa tgacgaaaga tatattagag
     1021 ttagaatctc aaaaaatgag tagtgacaca tttattgatg aaataaaaaa taattattta
     1081 tctattgtgg aaagtacaag aaaattaatt gatggtagac aaatagaatt agctataaaa
     1141 ttaataagag aagcaaacca gattttaatg attggtgtgg gttctagtgg aaatgcggct
     1201 agagaatttg agagtagttt gttaagaatt ggaataataa gtaagacggt aattgatacc
     1261 cattttcaac tcatgcatac tgcgttattg aaagataatg atttgataat agcgtttagt
     1321 ttatctggtt ccacaaaaga agttgaggaa actttattaa acgcaaaaag aaaaaatgtt
     1381 aaaattattt caataacaaa ttattcgtcc agaaatatag caaaattatc tgactgcgtt
     1441 cttttgacat caaaaaaaga atcttattta gagggtggta gtttaatggc taaggcttct
     1501 caactattca taattgatgt aatatgcact agactctctt taataaatta tgaagatact
     1561 atatgtaaaa aagaagagat tgc
//
LOCUS       DBEJNA010000079         1455 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEJNA010000079 DBEJNA010000000
VERSION     DBEJNA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.79"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..559
                     /locus_tag="ACL3JB_002059"
     CDS             <1..559
                     /locus_tag="ACL3JB_002059"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686707.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYVWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="ACL3JB_002060"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="ACL3JB_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0686708.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          506 a          208 c          264 g          477 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgt
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DBEJNA010000080         1358 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEJNA010000080 DBEJNA010000000
VERSION     DBEJNA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.80"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..1242
                     /locus_tag="ACL3JB_002061"
     CDS             join(<1..332,332..1242)
                     /locus_tag="ACL3JB_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0686709.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYPKKVKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKEIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
BASE COUNT          484 a          225 c          287 g          362 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaagga aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaat
//
LOCUS       DBEJNA010000081         1352 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.81, whole genome shotgun sequence.
ACCESSION   DBEJNA010000081 DBEJNA010000000
VERSION     DBEJNA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.81"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(151..291)
                     /locus_tag="ACL3JB_002062"
     CDS             complement(151..291)
                     /locus_tag="ACL3JB_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686710.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(288..470)
                     /locus_tag="ACL3JB_002063"
     CDS             complement(288..470)
                     /locus_tag="ACL3JB_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686711.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(472..1251)
                     /locus_tag="ACL3JB_002064"
     CDS             complement(472..1251)
                     /locus_tag="ACL3JB_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686712.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKMLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT          441 a          296 c          201 g          414 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagttt tctgcgactt ggattaccat ctagataagt ttaaagaacc aatccaatat
      181 cttgtaaaac agcaattgaa ctgcaaaaga aatgatcatc caaaagaatt tcacaatccc
      241 aataatcggt ttgataaaaa taatggcaag aagtccccag aaaaatttca ttctctctcc
      301 tctggcttaa tgagccaccg agccgtatcc attaacttgt cggcaataaa aagtttcccc
      361 agaccgacaa cggcattatc atctttcttt atcgttttca ttacttttac accttgcacg
      421 gtcaaaaagt aattaccata aattttagct agagttttta tgagtcccat attactctcc
      481 ttcgatgatt tcagcctctt ttcggattgt ttcaacatct tcttgatatt gaacttcact
      541 atagttaact agcttggaca attctttctg caagctttca cccatcggtt tcatagttgc
      601 aaaggttaaa ccacctgaaa tgataccacc caagatagga ataaatttcc ccattccttt
      661 ggccagccct cccttggtaa gattcacacc aaatattctt aagacttttt tcaaaatagg
      721 ataccaaagc atctttgtta aagctttatt aggtactgtt ttcattacct gtttggcaat
      781 tgttatacca ccagcacgta gcaaagcagc agttccattc acccccaaca tgacgcctag
      841 ataaagcaaa agggtatttt gagcatcttc actcaactca tcgcgtgaag cccaaagatc
      901 ctcataacca taaatataac ctaattcttg ggccaatttc agagagaaac cataaaattg
      961 agccacatca gctggaatgg taattgccat agcaagccct ccaggtaatc ctgccaaaac
     1021 agaagtccca ctcgctaata aaacattatc cctaatacag gcattagcca ctcgatctaa
     1081 gatttcttga gataagagag acgttggacc ttgttccaat aaggtaggaa tgtcctgtgg
     1141 acccaattct ttggaaaact tatccactaa aaatttcgaa cgatcaacct taacaactgg
     1201 tagttttacc acttgttgta atacttgcat agctaagtct tgttcagcca tatacaaact
     1261 ccttatttct tttttacacc ttatcatatt atatttccta caaaaaaagc attttctaat
     1321 tagataacat taaaaaatac agaacccctt tt
//
LOCUS       DBEJNA010000082         1099 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.82, whole genome shotgun sequence.
ACCESSION   DBEJNA010000082 DBEJNA010000000
VERSION     DBEJNA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.82"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(29..1099)
                     /gene="ltrA"
                     /locus_tag="ACL3JB_002065"
                     /pseudo
     CDS             complement(29..1099)
                     /gene="ltrA"
                     /locus_tag="ACL3JB_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          290 a          251 c          181 g          377 t
ORIGIN      
        1 tttgttctat tcttatttca ttttactata attgatagtg gtcgccccag ccagatacct
       61 tatctgctat ccatttagga acccctaact taagcaatcc ccataatcgt ctcgatttct
      121 tcttccattg cttccagata atcactcgta ggcgagtatg caaacgctca tctatgctgg
      181 tgactatact tttcatattt cccaatgaga aatagtttat ccatcctcga atagacaaat
      241 tcagttgctc aatacgtctt gttaggtcta tactccattt cctctgtgtt agtttcttca
      301 atttaagctt aaatctccaa acactatctt gatgtggacg acttttccaa ccatctgatg
      361 atttccagaa cccgaaacct agatatttca actctcttgg tctggtaatc ttagtcttgg
      421 tcatgtttac tttcagacct agccgtttct caataaaacg actgactgaa tacatcacac
      481 gcttagcggc tgcctcgctt ccgaccgtaa tcacacaatc gtctgcgtag cgaacaaatc
      541 gaagccctat cttttctaat tccttgtcca attcattaag catgatattg gataagagag
      601 gagataaatt tcctccctgt ggcgtgccaa ctagcgtttt ataacgttga ccgttaatga
      661 taacacctga atgaagatat ttacgaatca aggattccgt atctccgtct tcgataatgt
      721 tatgtactaa ggacatcaat ctatcttgag gaactgtatc gaaaaatttc tctaggtcta
      781 tgtccactat ccactcatag ccgtcattta agtactctaa gagcttcatg atggcttttt
      841 cacatgacct atttggtctg aatccatagc tcgtatctga gaaatggggt tcacaaatag
      901 ggctaataac ttgaacaatg gcctgttgaa tcattctatc cataactgtt ggaattccta
      961 gttgacggat gcctccgtct ggtttaggta tctcaacttt aagaactggt tgaggcttat
     1021 attttctctg ttttatcagt tccttagtca agcgccagtt ttgtctgaga taattatcca
     1081 tctcttcgat agtcattcc
//
LOCUS       DBEJNA010000083         1058 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.83, whole genome shotgun sequence.
ACCESSION   DBEJNA010000083 DBEJNA010000000
VERSION     DBEJNA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.83"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..559
                     /locus_tag="ACL3JB_002066"
     CDS             <1..559
                     /locus_tag="ACL3JB_002066"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686713.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(513..>1058)
                     /locus_tag="ACL3JB_002067"
     CDS             complement(513..>1058)
                     /locus_tag="ACL3JB_002067"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686714.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT          380 a          169 c          154 g          355 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat tttcaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgctcagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgctac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcattatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ataggtat
//
LOCUS       DBEJNA010000084         1055 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.84, whole genome shotgun sequence.
ACCESSION   DBEJNA010000084 DBEJNA010000000
VERSION     DBEJNA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.84"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            66..230
                     /locus_tag="ACL3JB_002068"
     CDS             66..230
                     /locus_tag="ACL3JB_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0686715.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            309..1037
                     /gene="yaaA"
                     /locus_tag="ACL3JB_002069"
     CDS             309..1037
                     /gene="yaaA"
                     /locus_tag="ACL3JB_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0686716.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
BASE COUNT          337 a          186 c          229 g          303 t
ORIGIN      
        1 aaaaaggttt atttaataaa tatatgttat aataaggtaa attaagccta atggaggaca
       61 aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc gctttgaaga
      121 taggtttttc tcagttcaag gagaaaaaag ataaattctt atctatctta acaagtttag
      181 ctggcatagc ccttgttctc gcggctgtct ggttaggatg gcccaaataa atagaaaaac
      241 ctctgtcaaa ccgaggtttt tcaaatgaat ttcttggttg tggctaaaaa atatgctaca
      301 ctatcaatat gaaaatttta atcccaacag caaaagaaat gaacacagac ttgccaagta
      361 tcgaggcaat tcctttaaaa ccagaaagtc agaccgtgct tgatgccttg gctctctatt
      421 ctgccagtca attggagagt ttctacaagg tatcagctga gaaagcggcg gaagaatttc
      481 aaaatatcca agctttgaaa aggcaaactg ctcaacacta tccagccttg aaactttttg
      541 atgggcttat gtaccgcaac attaagagag ataagctgac cgaggcggaa caagattatc
      601 ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt tgttccagcc ttgtcaccca
      661 tggctcctca ccgtttggat tttttgatga aattaaaagt cgctggtaag actttgaaga
      721 gccattggaa ggcagtctat gatgaagctc tgaagaagga agaagtgatt ttctctctct
      781 tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg gtgaccttca
      841 aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc aagaaagcgc
      901 gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg gaagcacgtc
      961 gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag ggattggttt
     1021 ttgtaaagga agtatagaaa tcagataaga gaaaa
//
LOCUS       DBEJNA010000085          900 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.85, whole genome shotgun sequence.
ACCESSION   DBEJNA010000085 DBEJNA010000000
VERSION     DBEJNA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.85"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..900
                     /locus_tag="ACL3JB_002070"
                     /pseudo
     CDS             1..900
                     /locus_tag="ACL3JB_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          274 a          199 c          167 g          260 t
ORIGIN      
        1 tgctttatgt gggcattgat atcgctaaaa ataaacacga tgttacagcc ttgaatgttc
       61 caggaaaaac tgttcttaaa ccactcactt tttcaaataa taaagctggt tttgaactct
      121 tagatctgtc tcttcgacag ctcaaccaag actgtctcat cgctcttaaa cttctttctg
      181 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta
      241 gatatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
      301 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
      361 aactcttgac acgctaccct aatcctcaga aaaggattga ggcaggattt gataagctga
      421 tagaaattaa gcattgaccg cttctaaaat tcaggatatc ctctcagtcg cacctcgttc
      481 tatcggaaca acatctcctg ctcgtgaatt cgaaatcatc gaaatcatca aacattacaa
      541 gagactcatt gacaaggcgg aaacatgtgt caatgacttg atggctgagt tcaactcggt
      601 catcacgacg gttactggga ttgggaatcg tttaggggcg gtcattttag ccgagattcg
      661 aaatattcat gcctttgata atcctgctca attacaagct ttcgctggac tggattcttc
      721 tatttatcag tcaggtcaga ttgatttagc tggaagaatg atcaaacggg gttcccctca
      781 tctgcggtgg gcactcatac aagctgccaa agcatgcgct cgcttttcac ctgcttttaa
      841 ggcctatctt aagactaagt tagaacaagg aaaacattac aatgtagcca tcatccacct
//
LOCUS       DBEJNA010000086          851 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.86, whole genome shotgun sequence.
ACCESSION   DBEJNA010000086 DBEJNA010000000
VERSION     DBEJNA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.86"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(43..234)
                     /locus_tag="ACL3JB_002071"
     CDS             complement(43..234)
                     /locus_tag="ACL3JB_002071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686717.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVMDRTDVVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFEEIFKEY"
     gene            248..610
                     /locus_tag="ACL3JB_002072"
     CDS             248..610
                     /locus_tag="ACL3JB_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0686718.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          271 a          128 c          154 g          298 t
ORIGIN      
        1 cgaaatctag tggaatgaat ctggaatagt ccatcgagct ttctaatact ctttgaaaat
       61 ctcttcaaac cacgtcaacg tcgccttgcc gtgtgtatgg ttactgactt cgtcagttct
      121 atccacaacc tcaaaacagt gttttgagct gactacgtca gttctatcca taacttcaaa
      181 acagtgtttt gagcaacctg cggctagttt cctagtctgc tctttggttt tcattgagta
      241 taacacattg ttagaagttg gtttaaattc cctaatcagt ttgttcacat ttaccttcga
      301 tatattatat cccatagtta aggttggtca tacagatgat tatagtcatg gagccgtaaa
      361 acttagtgtt tctttagttg acaaagatgc catgaaaaaa atatctgtaa ctgtaatagg
      421 atattttgaa ataaatatag atgaaaatat caccgatatt ctatacgtaa atggtactgc
      481 tattctttat cattatttac gttctattgt ttcaatagtt tcggcaattg atagcagtga
      541 agcaatgttg ctacctacca ttaatgtttt agagttacta gataaatctc aaccttttga
      601 agaagaataa tttattagct cactaaattg agggtaagga aaagtaaaat cagtaagaaa
      661 aatgtcttgc attatacagc aaccttttgg gaatgagtag atggattgaa taaaatttta
      721 ttaagagtgg atgatttatc tgtagattat tattggacag ttagtcttga agtagtctaa
      781 gaattaggtt ataatcagta gaatccttgc taataatgag gaggttagtt tatgtatagt
      841 agactgaatc t
//
LOCUS       DBEJNA010000087          838 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.87, whole genome shotgun sequence.
ACCESSION   DBEJNA010000087 DBEJNA010000000
VERSION     DBEJNA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.87"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..838
                     /locus_tag="ACL3JB_002073"
                     /pseudo
     CDS             1..838
                     /locus_tag="ACL3JB_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          251 a          182 c          148 g          257 t
ORIGIN      
        1 ctagaattct ccttagaaag cgtcgtttca agtgctatca ttgttctaaa atgatggtcg
       61 ctgaaacttc tatcgtcaag aagaatcatc aaattcctcg tattatcaac caaaaaattg
      121 cgcaaaagtt gattgagaag atttctatga ccgatattgc ccatcagctg gccatttcaa
      181 cttcaactgt cattcgaaag ctcaatgatt ctcactttga gcatgatttt tcgcgtcttc
      241 ctgagattat gtcctgggac gttgaaacag tccggggagt gactgtttca atcgggagat
      301 ggagatgagc tttattgcgc aagattttaa caatctcaat atcatcactg ttcttgaagg
      361 tagaacacaa gctgtcatcc gagatcactt tcttaaatat gatagagccg tccgatgtcg
      421 cgtcaaaatc attactatgg atatgtttag cccttactat gacttagcta aacagcttcg
      481 ctttcaaatt tctaggctca ggctgaaaca gtctcccagg ctgtttcact cccgaatgct
      541 aaaatcgttc ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
      601 catgtccaaa tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgt
      661 tactggaaac tcattcaaca ggatagccgt aaactgagtg ataagcgatt ttatcgccct
      721 acttttcgca tgcacttaac aaataaagaa attcttgaca agattttaag ctattcagaa
      781 gacttgaaac accactatca gatctatcaa ctcttacttt ttcactttca gaacaaag
//
LOCUS       DBEJNA010000088          773 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.88, whole genome shotgun sequence.
ACCESSION   DBEJNA010000088 DBEJNA010000000
VERSION     DBEJNA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.88"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(8..81)
                     /locus_tag="ACL3JB_002074"
     tRNA            complement(8..81)
                     /locus_tag="ACL3JB_002074"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="ACL3JB_002075"
     tRNA            complement(95..168)
                     /locus_tag="ACL3JB_002075"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="ACL3JB_002076"
     tRNA            complement(174..247)
                     /locus_tag="ACL3JB_002076"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="ACL3JB_002077"
     tRNA            complement(263..336)
                     /locus_tag="ACL3JB_002077"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="ACL3JB_002078"
     tRNA            complement(346..431)
                     /locus_tag="ACL3JB_002078"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="ACL3JB_002079"
     tRNA            complement(439..510)
                     /locus_tag="ACL3JB_002079"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="ACL3JB_002080"
     tRNA            complement(533..605)
                     /locus_tag="ACL3JB_002080"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="ACL3JB_002081"
     tRNA            complement(624..705)
                     /locus_tag="ACL3JB_002081"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
BASE COUNT          203 a          225 c          173 g          172 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gag
//
LOCUS       DBEJNA010000089          575 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.89, whole genome shotgun sequence.
ACCESSION   DBEJNA010000089 DBEJNA010000000
VERSION     DBEJNA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.89"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..>575)
                     /locus_tag="ACL3JB_002082"
     CDS             complement(<1..>575)
                     /locus_tag="ACL3JB_002082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0686719.1"
                     /translation="ADALVLAEADALVEAEAEALVLAEADALVLAEADALVDAEADAL
                     VLADSDALVDAEADALVDAEAEALVDAEADALVDAEAEALVLAEADALVDAEADALVD
                     AEAEALVLAEADALVDADSDAEILAEADALVLAEADALVEAEADAEVLALAEADALVD
                     AEAEALVEADSEAEVLAEAEALVDAEAEALV"
BASE COUNT          130 a          201 c          138 g          106 t
ORIGIN      
        1 tcaaccagtg cttcagcttc agcatcaacc agcgcctcgg cctcagcaag cacctcagct
       61 tctgaatcgg cctcaaccag cgcctcagcc tcagcatcaa cgagtgcgtc ggcctcagca
      121 agcgcaagta cctcagcgtc agcttccgcc tcaaccagtg cgtcggcttc agcaagcaca
      181 agtgcgtcag cctcagcaag tatctcagcg tctgaatcgg catcaacgag tgcgtccgct
      241 tcagcaagta ctagcgcctc agcctcagcg tcaaccagtg cgtcggcttc agcgtcaacg
      301 agtgcgtccg cttcagcaag tactagcgcc tcagcctcag cgtcaaccag tgcgtcagcc
      361 tcagcatcga caagcgcctc agcttcagca tcaacgagtg catcggcttc ggcgtcaacc
      421 agtgcatcag agtcagcaag taccagtgcg tcagcttccg catcaacaag tgcatcggct
      481 tcagcaagca ccagtgcgtc ggcttcagca agtactagcg cctcagcctc agcctcaacc
      541 agtgcgtcag cttcagcaag taccagtgcg tcggc
//
LOCUS       DBEJNA010000090          544 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.90, whole genome shotgun sequence.
ACCESSION   DBEJNA010000090 DBEJNA010000000
VERSION     DBEJNA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.90"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..>544
                     /locus_tag="ACL3JB_002083"
     CDS             <1..>544
                     /locus_tag="ACL3JB_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGR0686720.1"
                     /translation="LLRKRRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEK
                     ISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDN
                     LNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDR
                     FHIIQHLSRAMSRFRVQIMNQ"
BASE COUNT          158 a          116 c           94 g          176 t
ORIGIN      
        1 ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt tgctgagact
       61 cccctggtaa agaaaaatca ccaaatccct cgtatcatca accaaaaaat tgctcaaaag
      121 ttaattgaaa aaatttctat gactgatatt gcccatcagc tggccatttc aacttcaact
      181 gtcattcgca agctcaatga ctttcacttt gagcatgatt tttctcggct tccaaagatt
      241 atgtcttggg atgagtatgc cttcactaag ggaaagatga gtttcattgc gcaagatttt
      301 gataatctta atattatcac tgttcttgaa ggcagaacac aagctgtcat ccgaaatcac
      361 tttcttcgct acgatagagc cgttcgttgt caagtgaaaa tcattacgat ggatatgttt
      421 agtccttact atgacttggc taaacagctt tttccgtgtg ctaaaatcgt tctagatcgt
      481 ttccatatta tccaacatct cagccgtgcc atgagtcgtt ttcgtgttca aattatgaat
      541 cagt
//
LOCUS       DBEJNA010000091          515 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.91, whole genome shotgun sequence.
ACCESSION   DBEJNA010000091 DBEJNA010000000
VERSION     DBEJNA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.91"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            10..>515
                     /locus_tag="ACL3JB_002084"
     CDS             10..>515
                     /locus_tag="ACL3JB_002084"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686721.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLV"
BASE COUNT          181 a           59 c          110 g          165 t
ORIGIN      
        1 ggtggttgca tgaagaaagt gaaattaggt gaagtggcta cttttatcaa tggctatgct
       61 tttaaacctc aagattggtc atctgaaggg aaagagatta tcagaataca gaatctgact
      121 aaaacttcaa cagagataaa ttattattcg ggtacgattg ataaaaaata cattgttgaa
      181 gctggtgata ttcttatttc gtggtcgggt acattagggg tttttcagtg gcgtggaaga
      241 tccgcagtgt taaatcagca catttttaaa gtggtttttg ataagataga tatagataaa
      301 tcgtatttta aatatgttgt tgaaaaaggt ttacaagatg ctgtaaaaca tactcatggt
      361 tccacaatga aacatttaac taaaaaatat tttgataata ttatggtttc atatacaaat
      421 ttgggagagc aacaaagaat tgcaagtgag ctggatttgt taagcaagct gattttaagg
      481 agacaagaac aacttgaaga gcttaatcta cttgt
//
LOCUS       DBEJNA010000092          500 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.92, whole genome shotgun sequence.
ACCESSION   DBEJNA010000092 DBEJNA010000000
VERSION     DBEJNA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.92"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..>500
                     /locus_tag="ACL3JB_002085"
     CDS             <1..>500
                     /locus_tag="ACL3JB_002085"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0686722.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVA"
BASE COUNT          190 a           75 c           82 g          153 t
ORIGIN      
        1 tttggggaaa ataaaatatt tgaaagcatt gataacttat ttgatattat agatggtgat
       61 aggggcaaaa attatcctaa atcagatgag ttgtttagtg aggagtactg tttattttta
      121 aatacaaaga atgttactaa aaacggattt tcattcgata caaagcaatt tatcactaaa
      181 acaaaggata aattacttcg aaaaggcaaa cttgagcgtt atgatatagt cttgacaaca
      241 agaggtactg ttggaaatgt agcgtactac gatgaattaa taaaatataa acatttacgt
      301 ataaattcag gtatggtaat attacgtccc aagacaccaa atctaaatca gaaatttatt
      361 atccatgttt taaggaataa taattatagt cgagtgatat caggaagtgc tcagcctcag
      421 ttaccaatta caaaattaaa aaaaatactt ctccctctcc cccctctagc cctccaaaat
      481 gagttcgcag actttgtagc
//
LOCUS       DBEJNA010000093          402 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.93, whole genome shotgun sequence.
ACCESSION   DBEJNA010000093 DBEJNA010000000
VERSION     DBEJNA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.93"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..>402
                     /locus_tag="ACL3JB_002086"
     CDS             1..>402
                     /locus_tag="ACL3JB_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0686723.1"
                     /translation="MPYVGIDVAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKKFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILAR"
BASE COUNT          134 a           90 c           62 g          116 t
ORIGIN      
        1 atgccttatg tgggcattga tgtcgctaaa aataaacacg atgttacagc cttgaatgtt
       61 caaggaaaaa ctgttcttaa accactcact ttttcaaata ataaagctgg ttttgaactc
      121 ttagatctgt ctcttcgaca gctcaaccaa gactgtctca tcgctcttga agatactgga
      181 cattatgcct ttaatctact gaacttcctg catgaacaag gatataaagt ttacacctac
      241 aatcctttgc tcatcaagaa atttgccaaa tcattatcac ttcgcaagac taaaacggat
      301 aagaaagacg ctcatggcat cgctcttaaa cttctttctg accccaatcg tgaacaattt
      361 caacacgata atcggcaagt agaactaaaa atactggcta ga
//
LOCUS       DBEJNA010000094          382 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC46 isolate 666387
            SAMN38261153-rid24870423.denovo.94, whole genome shotgun sequence.
ACCESSION   DBEJNA010000094 DBEJNA010000000
VERSION     DBEJNA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261153
            Sequence Read Archive: SRR26833600
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575984.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575984.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 16:24:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,087
            CDSs (total)                      :: 2,048
            Genes (coding)                    :: 1,899
            CDSs (with protein)               :: 1,899
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 149
            Pseudo Genes (ambiguous residues) :: 0 of 149
            Pseudo Genes (frameshifted)       :: 82 of 149
            Pseudo Genes (incomplete)         :: 68 of 149
            Pseudo Genes (internal stop)      :: 50 of 149
            Pseudo Genes (multiple problems)  :: 43 of 149
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261153-rid24870423.denovo.94"
                     /strain="GPSC46"
                     /isolate="666387"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..114
                     /locus_tag="ACL3JB_002087"
     CDS             <1..114
                     /locus_tag="ACL3JB_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0686724.1"
                     /translation="QLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWENC"
BASE COUNT          113 a           48 c           89 g          132 t
ORIGIN      
        1 caattagtat ctgttcaagt tgacgaaaca gatgaagttg atggaatgcg atttagtaca
       61 ttcagtacaa accgttgcgg taactggagt gcttttagtt gggaaaattg ttaattcatt
      121 taaattgtaa actttaggga ttctctgaag ttatggatgt cgttccaata tgtgtacgtt
      181 ggaatgttag tgcttatatg gggggaacag aatcctctct tgattgaaga caagttagcc
      241 attaggctgg tttgtctctt tgtcaactgt agtgggttga tataatagta ttagtgagtg
      301 ggataaaagt ttcatttagt ttattcagta caaatttaac gggtcaagat ttattgaact
      361 gcaccccaat agttagacag aa
//
